P. Tsao

P. Tsao, R. Robbins, L. Balsam, 2005, The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation.

Overexpression of Human Copper/Zinc Superoxide Dismutase (SOD1) Suppresses Ischemia–Reperfusion Injury and Subsequent Development of Graft Coronary Artery Disease in Murine Cardiac Grafts

P. Tsao, R. Robbins, T. Kofidis, 2004, Circulation.

Mononuclear cell adherence to cultured endothelium is enhanced by hypertension and insulin resistance in healthy nondiabetic volunteers.

P. Tsao, T. McLaughlin, C. Lamendola, 1999, Circulation.

Adhesiveness of mononuclear cells in hypercholesterolemic humans is normalized by dietary L-arginine.

P. Tsao, J. Cooke, G. Theilmeier, 1997, Arteriosclerosis, thrombosis, and vascular biology.

Anti-ischaemic and endothelial protective actions of recombinant human osteogenic protein (hOP-1).

A. M. Lefer, P. Tsao, X. Ma, 1992, Journal of molecular and cellular cardiology.

Cholesterol-induced upregulation of angiotensin II and its effects on monocyte-endothelial interaction and superoxide production

P. Tsao, J. Cooke, J. Niebauer, 2001, Vascular medicine.

Decoding the Genomics of Abdominal Aortic Aneurysm

P. Tsao, M. Snyder, R. Dalman, 2018, Cell.

Endothelial dysfunction: clinical strategies for treating oxidant stress.

P. Tsao, S. Rockson, Brett E Fenster, 2003, American heart journal.

Pharmacologic profile of lipoxins A5 and B5: new biologically active eicosanoids.

A. M. Lefer, P. Tsao, A. Lefer, 1989, European journal of pharmacology.

Novel Role for the Potent Endogenous Inotrope Apelin in Human Cardiac Dysfunction

Euan A Ashley, Zohar Yakhini, Anya Tsalenko, 2003, Circulation.

In vivo genetic profiling and cellular localization of apelin reveals a hypoxia-sensitive, endothelial-centered pathway activated in ischemic heart failure.

Ahmad Y. Sheikh, P. Tsao, Z. Ali, 2008, American journal of physiology. Heart and circulatory physiology.

Flow-responsive remodeling after angioplasty is enhanced by high cholesterol diet. Prevention with pyrrolidine dithiocarbamate.

P. Tsao, A. Yeung, M. Ward, 2003, Atherosclerosis.

Time course and mechanism of endothelial dysfunction in isolated ischemic- and hypoxic-perfused rat hearts.

A. M. Lefer, P. Tsao, A. Lefer, 1990, The American journal of physiology.

Protocol II : Development of an Ex Vivo Model of Apoptosis

P. Tsao, J. Cooke, G. Gibbons, 1999 .

Asymmetric dimethylarginine impairs fibrinolytic activity in human umbilical vein endothelial cells via p38 MAPK and NF-κB pathways.

P. Tsao, Qin Zhang, Hong Jin, 2011, Thrombosis research.

Chitinase 3 like 1 is a regulator of smooth muscle cell physiology and atherosclerotic lesion stability

P. Tsao, U. Hedin, N. Leeper, 2021 .

Minority-centric meta-analyses of blood lipid levels identify novel loci in the Population Architecture using Genomics and Epidemiology (PAGE) study

Stephanie A. Bien, C. Carlson, T. Assimes, 2020, PLoS genetics.

Influences of Aortic Motion and Curvature on Vessel Expansion in Murine Experimental Aneurysms

Charles A. Taylor, P. Tsao, C. Goergen, 2011, Arteriosclerosis, thrombosis, and vascular biology.

Regulatory variants in TCF7L2 are associated with thoracic aortic aneurysm.

P. Tsao, S. Leal, K. Eagle, 2021, American journal of human genetics.

Assessment of Elastase-Induced Murine Abdominal Aortic Aneurysms: Comparison of Ultrasound Imaging with In Situ Video Microscopy

P. Tsao, M. McConnell, R. Dalman, 2011, Journal of biomedicine & biotechnology.

Arginine: a new therapy for atherosclerosis?

P. Tsao, J. Cooke, 1997, Circulation.

Cytoprotective effects of nitric oxide.

P. Tsao, J. Cooke, P. Tsao, 1993, Circulation.

Chronic Nicotine Exposure Induces Murine Aortic Remodeling and Stiffness Segmentation—Implications for Abdominal Aortic Aneurysm Susceptibility

Anand K. Ramasubramanian, P. Tsao, M. Elvers, 2018, Front. Physiol..

Sphingosine-1-Phosphate Prevents Tumor Necrosis Factor-&agr;–Mediated Monocyte Adhesion to Aortic Endothelium in Mice

Michael D. Davis, P. Tsao, C. Hedrick, 2005, Arteriosclerosis, thrombosis, and vascular biology.

Synergism between superoxide dismutase and sodium nitrite in cardioprotection following ischemia and reperfusion.

A. M. Lefer, P. Tsao, G. Johnson, 1990, American heart journal.

Activated neutrophils aggravate endothelial dysfunction after reperfusion of the ischemic feline myocardium.

A. M. Lefer, P. Tsao, Xinliang Ma, 1992, American heart journal.

Anti-WC and Edothelialprotective Actions ofRecombinant Human Osteogenic Protein (hop-1)

A. M. Lefer, P. Tsao, Xinliang Ma, 1992 .

Neutrophil-mediated vasoconstriction and endothelial dysfunction in low-flow perfusion-reperfused cat coronary artery.

A. M. Lefer, P. Tsao, Xinliang Ma, 1991, Circulation research.

EXPERIMENTAL STUDIES Dietary i e Prevents Atherogenesils in the Coronary Artery of the er

P. Tsao, J. Cooke, H. Drexler, 2016 .

Dietary arginine prevents atherogenesis in the coronary artery of the hypercholesterolemic rabbit.

P. Tsao, J. Cooke, H. Drexler, 1994, Journal of the American College of Cardiology.

Hyperlipidemia does not affect development of elastase-induced abdominal aortic aneurysm in mice.

H. C. Beck, P. Tsao, J. Lindholt, 2020, Atherosclerosis.

Histopathology of restenosis

P. Tsao, A. Carter, 2005 .

Systemic Upregulation of IL-10 (Interleukin-10) Using a Nonimmunogenic Vector Reduces Growth and Rate of Dissecting Abdominal Aortic Aneurysm

P. Tsao, J. Hamming, P. Quax, 2018, Arteriosclerosis, thrombosis, and vascular biology.

The power of genetic diversity in genome-wide association studies of lipids

Christopher D. Brown, Aaron F. McDaid, Peter K. Joshi, 2021, Nature.

Publisher Correction: A multi-ethnic epigenome-wide association study of leukocyte DNA methylation and blood lipids

May E. Montasser, Min A. Jhun, S. Horvath, 2021, Nature communications.

Asymmetric dimethyl L-arginine (ADMA) is a critical regulator of myocardial reperfusion injury.

P. Tsao, J. Cooke, O. Pachinger, 2007, Cardiovascular research.

Cardioprotective effects of authentic nitric oxide in myocardial ischemia with reperfusion

A. M. Lefer, P. Tsao, G. Johnson, 1991, Critical care medicine.

Endothelial alterations in hypercholesterolemia: more than simply vasodilator dysfunction.

P. Tsao, J. Cooke, John P. Cooke, 1998, Journal of cardiovascular pharmacology.

Discordant Effects of Dietary L-Arginine on Vascular Structure and Reactivity in Hypercholesterolemic Rabbits

P. Tsao, D. Bloch, J. Cooke, 1995, Journal of cardiovascular pharmacology.

Shock- and ischemia-induced mechanisms of impairment of endothelium-mediated vasodilation.

P. Tsao, X. Ma, A. Lefer, 1991, Chest.

A Special Report on the NHLBI Initiative to Study Cellular and Molecular Mechanisms of Arterial Stiffness and Its Association With Hypertension

C. A. Figueroa, P. Tsao, J. Humphrey, 2017, Circulation research.

Creation of murine experimental abdominal aortic aneurysms with elastase.

P. Tsao, R. Dalman, J. Azuma, 2009, Journal of visualized experiments : JoVE.

Harmonizing Genetic Ancestry and Self-identified Race/Ethnicity in Genome-wide Association Studies.

Julie A. Lynch, Yan V. Sun, T. Assimes, 2019, American journal of human genetics.

Response to Letters Regarding Article, "Segmental Aortic Stiffening Contributes to Experimental Abdominal Aortic Aneurysm Development".

P. Tsao, E. Kuhl, R. Dalman, 2016, Circulation.

Monday, 27 August 2012

V. V. Ivanenko, E. A. Medvedeva, Michail I. Papafaklis, 2012 .

Fluid flow inhibits endothelial adhesiveness. Nitric oxide and transcriptional regulation of VCAM-1.

P. Tsao, J. Cooke, John P. Cooke, 1996, Circulation.

Loss of CDKN2B Promotes p53-Dependent Smooth Muscle Cell Apoptosis and Aneurysm Formation

Karen Cheng, Eric E Schadt, Yoko Kojima, 2013, Arteriosclerosis, thrombosis, and vascular biology.

Transcriptomic Profiling Maps Anatomically Patterned Subpopulations among Single Embryonic Cardiac Cells.

Bin Zhou, Stephen R Quake, Thomas Quertermous, 2016, Developmental cell.

Correction: A missense variant in Mitochondrial Amidoxime Reducing Component 1 gene and protection against liver disease

J. Danesh, P. Tsao, S. Gabriel, 2021, PLoS genetics.

Time course of endothelial dysfunction and myocardial injury during myocardial ischemia and reperfusion in the cat.

A. M. Lefer, P. Tsao, G. Johnson, 1990, Circulation.

High heritability of ascending aortic diameter and multi-ethnic prediction of thoracic aortic disease.

Manuel A. Rivas, Manuel A Rivas, P. Tsao, 2020, medRxiv.

Genome-wide association analysis of venous thromboembolism identifies new risk loci and genetic overlap with arterial vascular disease

Yan V. Sun, Donald R. Miller, Mary E. Haas, 2019, Nature Genetics.

Dichloroacetate prevents restenosis in preclinical animal models of vessel injury

P. Tsao, A. Yeung, S. Blankenberg, 2014, Nature.

Novel Vascular Molecule Involved in Monocyte Adhesion to Aortic Endothelium in Models of Atherogenesis

P. Tsao, J. Cooke, E. Butcher, 1997, The Journal of experimental medicine.

Mouse Strain–Specific Differences in Vascular Wall Gene Expression and Their Relationship to Vascular Disease

R. Tibshirani, B. Efron, P. Tsao, 2004, Arteriosclerosis, thrombosis, and vascular biology.

GWAS of epigenetic aging rates in blood reveals a critical role for TERT

M. Levine, S. Horvath, R. Marioni, 2018, Nature Communications.

Three-Dimensional Microstructural Changes in Murine Abdominal Aortic Aneurysms Quantified Using Immunofluorescent Array Tomography

Charles A. Taylor, P. Tsao, Stephen J. Smith, 2012, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

Dietary L-arginine supplementation normalizes platelet aggregation in hypercholesterolemic humans.

P. Tsao, J. Cooke, G. Theilmeier, 1997, Journal of the American College of Cardiology.

Atherosclerosis: Role of NO

P. Tsao, J. Cooke, 1999 .

Asymmetric dimethylarginine (ADMA): a novel risk factor for endothelial dysfunction: its role in hypercholesterolemia.

P. Tsao, J. Cooke, T. Blaschke, 1998, Circulation.

Involvement of Myeloid Cells and Noncoding RNA in Abdominal Aortic Aneurysm Disease

P. Tsao, J. Spin, H. Eckstein, 2020, Antioxidants & redox signaling.

Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals

Tom R. Gaunt, James M. Eales, Dajiang J. Liu, 2020, Nature Genetics.

DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases

Audrey Y. Chu, Min A. Jhun, S. Horvath, 2016, Genome Biology.

NOS inhibition accelerates atherogenesis: reversal by exercise.

P. Tsao, J. Cooke, J. Niebauer, 2003, American journal of physiology. Heart and circulatory physiology.

Genome-wide association analysis of venous thromboembolism identifies new risk loci and genetic overlap with arterial vascular disease

Yan V. Sun, Donald R. Miller, Mary E. Haas, 2019, Nature Genetics.

Pioglitazone Increases the Proportion of Small Cells in Human Abdominal Subcutaneous Adipose Tissue

P. Tsao, T. McLaughlin, C. Lamendola, 2010, Obesity.

Enhanced proportion of small adipose cells in insulin-resistant vs insulin-sensitive obese individuals implicates impaired adipogenesis

A. Sherman, P. Tsao, T. McLaughlin, 2007, Diabetologia.

Cloud-based interactive analytics for terabytes of genomic variants data

Michael Snyder, Jonathan Bingham, Cuiping Pan, 2017, Bioinform..

MicroRNA-Mediated Therapy Modulating Blood–Brain Barrier Disruption Improves Vascular Cognitive Impairment

P. Tsao, Ting-Ting Huang, J. Spin, 2018, Arteriosclerosis, thrombosis, and vascular biology.

Cross-trait analyses with migraine reveal widespread pleiotropy and suggest a vascular component to migraine headache

Katherine M. Siewert, N. Eriksson, A. Hofman, 2020, International journal of epidemiology.

A multi-ethnic epigenome-wide association study of leukocyte DNA methylation and blood lipids

May E. Montasser, Min A. Jhun, S. Horvath, 2021, Nature Communications.

MicroRNA-21 Blocks Abdominal Aortic Aneurysm Development and Nicotine-Augmented Expansion

P. Tsao, M. McConnell, R. Dalman, 2012, Science Translational Medicine.

Micromanaging Abdominal Aortic Aneurysms

P. Tsao, J. Spin, R. Toh, 2013, International journal of molecular sciences.

Dimethylarginine Dimethylaminohydrolase Regulates Nitric Oxide Synthesis: Genetic and Physiological Evidence

P. Tsao, J. Cooke, P. Vallance, 2003, Circulation.

Plasma concentrations of asymmetric dimethylarginine are increased in patients with type 2 diabetes mellitus.

J P Cooke, P. Tsao, T. McLaughlin, 2001, The American journal of cardiology.

The relationship between circulating lipids and breast cancer risk: A Mendelian randomization study

Katherine M. Siewert, T. Assimes, P. Tsao, 2020, PLoS medicine.

Assessing a causal relationship between circulating lipids and breast cancer risk via Mendelian randomization

Katherine M. Siewert, T. Assimes, P. Tsao, 2019 .

Cardiomyocyte-specific Bcl-2 overexpression attenuates ischemia-reperfusion injury, immune response during acute rejection, and graft coronary artery disease.

P. Tsao, S. Nakae, R. Robbins, 2004, Blood.

Interactive Analytics for Very Large Scale Genomic Data

Jonathan Bingham, Cuiping Pan, Nicole Deflaux, 2015, bioRxiv.

Coronary Artery Disease Risk of Familial Hypercholesterolemia Genetic Variants Independent of Historical Cholesterol Exposure

T. Assimes, P. Tsao, J. Knowles, 2020, medRxiv.

Genetic Variation in Blood Pressure and Lifetime Risk of Peripheral Artery Disease: A Mendelian Randomization Study

T. Assimes, P. Tsao, D. Rader, 2020, medRxiv.

Apelin and APJ orchestrate complex tissue-specific control of cardiomyocyte hypertrophy and contractility in the hypertrophy-heart failure transition.

P. Tsao, E. Ashley, D. Bernstein, 2018, American journal of physiology. Heart and circulatory physiology.

MicroRNA-29b regulation of abdominal aortic aneurysm development.

P. Tsao, J. Azuma, L. Maegdefessel, 2014, Trends in cardiovascular medicine.

Vascular smooth muscle cell phenotypic plasticity: focus on chromatin remodelling.

P. Tsao, J. Spin, L. Maegdefessel, 2012, Cardiovascular research.

Chromatin Remodeling Pathways in Smooth Muscle Cell Differentiation, and Evidence for an Integral Role for p300

P. Tsao, T. Quertermous, J. Spin, 2010, PloS one.

Pathogenesis of abdominal aortic aneurysms: microRNAs, proteases, genetic associations.

P. Tsao, R. Dalman, L. Maegdefessel, 2014, Annual review of medicine.

MicroRNAs in Abdominal Aortic Aneurysm.

P. Tsao, J. Spin, U. Raaz, 2015, Current vascular pharmacology.

accurately predict atherosclerosis in mice Proteomic profiles of serum inflammatory markers

P. Tsao, D. Tilley, T. Kurita-Ochiai, 2015 .

Prospective Transcriptomic Pathway Analysis of Human Lymphatic Vascular Insufficiency: Identification and Validation of a Circulating Biomarker Panel

P. Tsao, Shin Lin, S. Rockson, 2012, PloS one.

In Vivo Bioluminescence Imaging of Inducible Nitric Oxide Synthase Gene Expression in Vascular Inflammation

P. Tsao, M. McConnell, C. Contag, 2011, Molecular Imaging and Biology.

Apelin signaling antagonizes Ang II effects in mouse models of atherosclerosis.

Ahmad Y. Sheikh, P. Tsao, E. Ashley, 2008, The Journal of clinical investigation.

Proteomic profiles of serum inflammatory markers accurately predict atherosclerosis in mice.

P. Tsao, T. Quertermous, R. Wagner, 2006, Physiological genomics.

Plasma asymmetric dimethylarginine concentrations are elevated in obese insulin-resistant women and fall with weight loss.

P. Tsao, C. Lamendola, T. McLaughlin, 2006, The Journal of clinical endocrinology and metabolism.

miR-24 limits aortic vascular inflammation and murine abdominal aneurysm development

P. Tsao, M. McConnell, A. Hamsten, 2014, Nature Communications.

Epigenetic clock analysis of diet, exercise, education, and lifestyle factors

M. Levine, S. Horvath, Toshiko Tanaka, 2017, Aging.

Long-term effects of polymer-based, slow-release, sirolimus-eluting stents in a porcine coronary model.

P. Tsao, A. Yeung, A. Carter, 2004, Cardiovascular research.

Exposure to shear stress alters endothelial adhesiveness. Role of nitric oxide.

J P Cooke, P. Tsao, J. Cooke, 1995, Circulation.

Insulin resistance and compensatory hyperinsulinemia: the key player between cigarette smoking and cardiovascular disease?

P. Tsao, G. Reaven, 2003, Journal of the American College of Cardiology.

Using Pre-existing Microarray Datasets to Increase Experimental Power: Application to Insulin Resistance

Russ B. Altman, Margaret C. Cam, Samuel W. Cushman, 2010, PLoS Comput. Biol..

Role of endothelial dysfunction in the pathogenesis of reperfusion injury after myocardial ischemia

A. M. Lefer, P. Tsao, Xinliang Ma, 1991, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Evaluation of height as a disease risk factor through a phenome-wide association study of genetically-predicted height

Yan V. Sun, T. Assimes, P. Tsao, 2021, medRxiv.

Anti-CD43 inhibits monocyte-endothelial adhesion in inflammation and atherogenesis.

P. Tsao, J. Cooke, E. Butcher, 1997, Blood.

Genetic Determinants of Peripheral Artery Disease

P. Tsao, S. Damrauer, D. Klarin, 2021, Circulation research.

Multi-trait GWAS of atherosclerosis detects novel pleiotropic loci

T. Assimes, P. Tsao, D. Rader, 2021, medRxiv.

Genotyping Array Design and Data Quality Control in the Million Veteran Program.

Grant D. Huang, Teresa A. Webster, T. Assimes, 2020, American journal of human genetics.

Measuring genetic variation in the multi-ethnic Million Veteran Program (MVP)

Grant D. Huang, Teresa A. Webster, T. Assimes, 2020, bioRxiv.

Association of APOL1 Risk Alleles with Cardiovascular Disease in African Americans in the Million Veteran Program.

Yan V. Sun, Donald R. Miller, T. Assimes, 2019, Circulation.

Trellis for efficient data and task management in the VA Million Veteran Program

P. Tsao, Cuiping Pan, Paul Billing Ross, 2021, Scientific Reports.

Hummingbird: efficient performance prediction for executing genomic applications in the cloud

Frank Mueller, Amir Alavi, Cuiping Pan, 2021, Bioinform..

Genetics of Smoking and Risk of Atherosclerotic Cardiovascular Diseases

T. Assimes, P. Tsao, D. Rader, 2021, JAMA network open.

Stent-Based Delivery of Sirolimus Reduces Neointimal Formation in a Porcine Coronary Model

P. Tsao, G. Papandreou, A. Yeung, 2001, Circulation.

Mechanotransduction of endothelial oxidative stress induced by cyclic strain.

P. Tsao, David S Wang, D. Proffit, 2001, Endothelium : journal of endothelial cell research.

Cyclic strain induces reactive oxygen species production via an endothelial NAD(P)H oxidase

P. Tsao, H. Matsushita, Kuen‐ho Lee, 2001, Journal of cellular biochemistry. Supplement.

Genetic Evidence for Repurposing of GLP1R (Glucagon‐Like Peptide‐1 Receptor) Agonists to Prevent Heart Failure

P. Tsao, V. Zuber, B. Voight, 2021, Journal of the American Heart Association.

Molecular Signatures Determining Coronary Artery and Saphenous Vein Smooth Muscle Cell Phenotypes: Distinct Responses to Stimuli

P. Tsao, A. Tsalenko, L. Bruhn, 2006 .

Molecular signatures determining coronary artery and saphenous vein smooth muscle cell phenotypes: distinct responses to stimuli.

P. Tsao, A. Tsalenko, L. Bruhn, 2006, Arteriosclerosis, thrombosis, and vascular biology.

Red blood cells serve as intravascular carriers of myeloperoxidase.

P. Tsao, S. Blankenberg, V. Rudolph, 2014, Journal of molecular and cellular cardiology.

Inhibition of microRNA-29b reduces murine abdominal aortic aneurysm development.

Alicia Deng, Michael V McConnell, Philip S Tsao, 2012, The Journal of clinical investigation.

Identification and validation of N-acetyltransferase 2 as an insulin sensitivity gene.

T. Assimes, P. Tsao, J. Pankow, 2016, The Journal of clinical investigation.

Identification and validation of N-acetyltransferase 2 as an insulin sensitivity gene

T. Assimes, P. Tsao, J. Pankow, 2015 .

New options with dabigatran etexilate in anticoagulant therapy

P. Tsao, J. Spin, J. Azuma, 2010, Vascular health and risk management.

Modern role for clopidogrel in management of atrial fibrillation and stroke reduction

P. Tsao, J. Azuma, L. Maegdefessel, 2010, Vascular health and risk management.

Vascular Health and Risk Management Dovepress New Options with Dabigatran Etexilate in Anticoagulant Therapy Venous Thromboembolic Disease

P. Tsao, J. Spin, J. Azuma, 2022 .

Genetic analysis in European ancestry individuals identifies 517 loci associated with liver enzymes

Yan V. Sun, P. Elliott, A. Uitterlinden, 2021, Nature Communications.

A Phenome-Wide Association Study of genes associated with COVID-19 severity reveals shared genetics with complex diseases in the Million Veteran Program

P. Tsao, Hongyu Zhao, S. Luoh, 2021, medRxiv.

Hypertension-enhanced monocyte adhesion in experimental atherosclerosis.

P. Tsao, C. Zarins, P. Huie, 1996, Journal of vascular surgery.

Role of MicroRNAs in acceleration of vascular endothelial senescence

P. Tsao, M. Mogi, J. Spin, 2022, Biochemistry and biophysics reports.

Diabetic Cardiovascular Disease Induced by Oxidative Stress

P. Tsao, J. Spin, U. Raaz, 2015, International journal of molecular sciences.

Chitinase 3 like 1 (CHI3L1) is a regulator of smooth muscle cell physiology and atherosclerotic lesion stability.

P. Tsao, U. Hedin, N. Leeper, 2021, Cardiovascular research.

Apelin decreases lipolysis via G(q), G(i), and AMPK-Dependent Mechanisms.

P. Tsao, T. Quertermous, G. Reaven, 2011, Endocrinology.

Asymmetric dimethylarginine increases mononuclear cell adhesiveness in hypercholesterolemic humans.

P. Tsao, J. Cooke, T. Blaschke, 2000, Arteriosclerosis, thrombosis, and vascular biology.

MicroRNA‐26a is a novel regulator of vascular smooth muscle cell function

P. Tsao, T. Quertermous, H. Chun, 2011, Journal of cellular physiology.

Nitric oxide regulates monocyte chemotactic protein-1.

P. Tsao, J. Cooke, J. Shyy, 1997, Circulation.

Short polymers of arginine rapidly translocate into vascular cells: effects on nitric oxide synthesis.

P. Tsao, J. Cooke, J. Rothbard, 2002, Circulation journal : official journal of the Japanese Circulation Society.

Antioxidants from diet or supplements do not alter inflammatory markers in adults with cardiovascular disease risk. A pilot randomized controlled trial.

P. Tsao, C. Gardner, J. Rigdon, 2018, Nutrition research.

Low- and high-dose plant and marine (n-3) fatty acids do not affect plasma inflammatory markers in adults with metabolic syndrome.

P. Tsao, W. Harris, C. Gardner, 2011, The Journal of nutrition.

Relationship between insulin resistance and an endogenous nitric oxide synthase inhibitor.

P. Tsao, C. Lamendola, T. McLaughlin, 2002, JAMA.

Nitric Oxide and Vascular Disease

P. Tsao, J. Cooke, A. J. Maxwell, 2000 .

Regression of atherosclerosis: role of nitric oxide and apoptosis.

P. Tsao, J. Cooke, G. Gibbons, 1999, Circulation.

Circulating markers of abdominal aortic aneurysm presence and progression.

P. Tsao, J. Golledge, P. Norman, 2008, Circulation.

Erratum: miR-24 limits aortic vascular inflammation and murine abdominal aneurysm development

P. Tsao, M. McConnell, A. Hamsten, 2015, Nature Communications.

Distribution of asymmetric dimethylarginine among 980 healthy, older adults of different ethnicities.

P. Tsao, A. Go, M. Hlatky, 2010, Clinical chemistry.

Diabetes mellitus enhances vascular matrix metalloproteinase activity: role of oxidative stress.

P. Tsao, Wei Li, D. Harrison, 2001, Circulation research.

Development of a polygenic risk score to improve detection of peripheral artery disease

P. Tsao, E. Ross, N. Leeper, 2022, Vascular medicine.

Transcriptional profiling and network analysis of the murine angiotensin II-induced abdominal aortic aneurysm.

P. Tsao, J. Dyer, R. Dalman, 2011, Physiological genomics.

Induction of nitric oxide synthase in the human cardiac allograft is associated with contractile dysfunction of the left ventricle.

P. Tsao, S. Hunt, R. Johns, 1996, Circulation.

Unresolved Issues in RNA Therapeutics in Vascular Diseases With a Focus on Aneurysm Disease

P. Tsao, U. Raaz, K. Mattern, 2021, Frontiers in Cardiovascular Medicine.

Inhibition of heart transplant injury and graft coronary artery disease after prolonged organ ischemia by selective protein kinase C regulators.

P. Tsao, D. Mochly‐Rosen, R. Robbins, 2005, The Journal of thoracic and cardiovascular surgery.

University of Groningen Levosimendan displays anti-inflammatory effects and decreases MPO bioavailability in patients with severe heart failure

P. Tsao, J. Spin, V. Rudolph, 2017 .

Levosimendan displays anti-inflammatory effects and decreases MPO bioavailability in patients with severe heart failure

P. Tsao, J. Spin, V. Rudolph, 2015, Scientific Reports.

Does enhanced insulin sensitivity improve sleep measures in patients with obstructive sleep apnea: a randomized, placebo-controlled pilot study.

P. Tsao, C. Lamendola, C. Kushida, 2016, Sleep medicine.

A MUC5B gene polymorphism, rs35705950-T, confers protective effects in COVID-19 infection

P. Tsao, J. McGeary, P. Wilson, 2021, medRxiv.

Etiology and Pathogenesis of Atherosclerosis

P. Tsao, M. Stühlinger, 2003 .

Baseline Characterization and Annual Trends of Body Mass Index for a Mega-Biobank Cohort of US Veterans 2011–2017

Grant D. Huang, P. Tsao, J. Concato, 2018, Journal of health research and reviews in developing countries.

Low-and High-Dose Plant and Marine ( n-3 ) Fatty Acids Do Not Affect Plasma Inflammatory Markers in Adults with Metabolic Syndrome 1 – 4

P. Tsao, W. Harris, C. Gardner, 2011 .

Hemodynamic regulation of reactive oxygen species: implications for vascular diseases.

P. Tsao, J. Spin, R. Toh, 2014, Antioxidants & redox signaling.

E-Cigarettes and Cardiopulmonary Health.

P. Tsao, P. Hopke, J. Samet, 2021, Function.

Association Between Genetic Variation in Blood Pressure and Increased Lifetime Risk of Peripheral Artery Disease

Jacob M. Keaton, T. Assimes, P. Tsao, 2021, Arteriosclerosis, thrombosis, and vascular biology.

Apelin is necessary for the maintenance of insulin sensitivity.

P. Tsao, T. Quertermous, G. Reaven, 2009, American journal of physiology. Endocrinology and metabolism.

MicroRNA miR-29b regulates diabetic aortic remodeling and stiffening

P. Tsao, M. Stumvoll, G. Hasenfuss, 2021, Molecular therapy. Nucleic acids.

Effect of Pioglitazone on Cardiometabolic Risk in Patients With Obstructive Sleep Apnea.

P. Tsao, C. Lamendola, C. Kushida, 2017, The American journal of cardiology.

Endothelial Alterations in Atherosclerosis: The Role of Nitric Oxide

P. Tsao, J. Cooke, 1997 .

Stent-based immunosuppressive therapies for the prevention of restenosis.

P. Tsao, A. Yeung, A. Carter, 2003, Cardiovascular radiation medicine.

Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

Andrew D. Johnson, Yan V. Sun, Sara M. Willems, 2018, Nature Genetics.

Mendelian Randomization Analysis of Hemostatic Factors and Their Contribution to Peripheral Artery Disease—Brief Report

Yan V. Sun, Donald R. Miller, T. Assimes, 2020, Arteriosclerosis, thrombosis, and vascular biology.

Is NO an endogenous antiatherogenic molecule?

P. Tsao, J. Cooke, P. Tsao, 1994, Arteriosclerosis and thrombosis : a journal of vascular biology.

Phenome-wide association of 1809 phenotypes and COVID-19 disease progression in the Veterans Health Administration Million Veteran Program

P. Tsao, K. Liao, C. O’Donnell, 2021, PloS one.

Circulating chemokines accurately identify individuals with clinically significant atherosclerotic heart disease.

T. Assimes, P. Tsao, A. Go, 2007, Physiological genomics.

Coronary risk assessment among intermediate risk patients using a clinical and biomarker based algorithm developed and validated in two population cohorts

R. Tibshirani, T. Hastie, P. Tsao, 2012, Current medical research and opinion.

Therapeutic perspective on vascular cognitive impairment.

P. Tsao, M. Mogi, J. Spin, 2019, Pharmacological research.

Inflammation in subcutaneous adipose tissue: relationship to adipose cell size

P. Tsao, T. McLaughlin, C. Lamendola, 2010, Diabetologia.

Interaction of diabetes and hypertension on determinants of endothelial adhesiveness.

P. Tsao, J. Cooke, G. Reaven, 1998, Arteriosclerosis, thrombosis, and vascular biology.

Human Engineered Heart Muscles Engraft and Survive Long Term in a Rodent Myocardial Infarction Model.

Malte Tiburcy, Vincent C. Chen, Oscar J Abilez, 2015, Circulation research.

A human ferritin iron oxide nano‐composite magnetic resonance contrast agent

P. Tsao, M. McConnell, T. Douglas, 2008, Magnetic resonance in medicine.

Adherence of Mononuclear Cells to Endothelium In Vitro Is Increased in Patients With NIDDM

P. Tsao, J. Cooke, G. Reaven, 1997, Diabetes Care.

Differential adipogenic and inflammatory properties of small adipocytes in Zucker Obese and Lean rats

P. Tsao, A. Sherman, T. McLaughlin, 2010, Diabetes & vascular disease research.

A large-scale multi-ethnic genome-wide association study of coronary artery disease

Yan V. Sun, Donald R. Miller, T. Assimes, 2021 .

MENDELIAN RANDOMIZATION Urate , Blood Pressure , and Cardiovascular Disease Evidence From Mendelian Randomization and Meta-Analysis of Clinical Trials

P. Elliott, P. Tsao, V. Zuber, 2021 .

Urate, Blood Pressure, and Cardiovascular Disease

P. Elliott, P. Tsao, V. Zuber, 2020, Hypertension.

The Use of Immunofluorescent Array Tomography to Study the Three-Dimensional Microstructure of Murine Blood Vessels

Charles A. Taylor, P. Tsao, Stephen J. Smith, 2011 .

Exosome miR-501-3p Elevation Contributes to Progression of Vascular Stiffness

P. Tsao, M. Mogi, J. Spin, 2021, Circulation reports.

Increased aortic stiffness in the insulin-resistant Zucker fa/fa rat.

Charles A. Taylor, P. Tsao, G. Reaven, 2005, American journal of physiology. Heart and circulatory physiology.

Genome-wide Association Study of Peripheral Artery Disease in the Million Veteran Program

Patrick R. Alba, Olga V. Patterson, Yan V. Sun, 2019, Nature Medicine.

microRNA-based biomarker for dementia

P. Tsao, M. Mogi, Kensuke Toyama, 2019, Aging.

Building the case for mitochondrial transplantation as an anti-aging cardiovascular therapy

P. Tsao, Colwyn A. Headley, Colwyn A. Headley, 2023, Frontiers in Cardiovascular Medicine.

A statistical quality assessment method for longitudinal observations in electronic health record data with an application to the VA million veteran program

Mei-Chiung Shih, Philip S. Tsao, Ilana Belitskaya-Levy, 2021, BMC Medical Informatics and Decision Making.

Measurement of insulin-mediated glucose uptake: direct comparison of the modified insulin suppression test and the euglycemic, hyperinsulinemic clamp.

T. Assimes, P. Tsao, J. Knowles, 2013, Metabolism: clinical and experimental.

HIF-1 regulates hypoxia- and insulin-induced expression of apelin in adipocytes.

Ahmad Y. Sheikh, P. Tsao, T. Quertermous, 2007, American journal of physiology. Endocrinology and metabolism.

An Automated Algorithm to Quantify Collagen Distribution in Aortic Wall

Anand K. Ramasubramanian, P. Tsao, A. Ramasubramanian, 2018, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

A Missense Variant in the IL-6 Receptor and Protection from Peripheral Artery Disease.

T. Assimes, P. Tsao, B. Voight, 2021, Circulation research.

Anti-atherogenic effect of nuts: is the answer NO?

P. Tsao, J. Cooke, H. Drexler, 1993, Archives of internal medicine.

Go with the flow

P. Tsao, I. Procaccia, J. Cooke, 2001, Circulation.

Acute effects of unsaturated fatty acids in splanchnic artery occlusion shock.

P. Tsao, A. Lefer, N. Aoki, 1989, Prostaglandins, leukotrienes, and essential fatty acids.

GWAS of epigenetic aging rates in blood reveals a critical role for TERT

M. Levine, S. Horvath, R. Marioni, 2017, bioRxiv.

Hypercholesterolemia impairs exercise capacity in mice

P. Tsao, D. Bernstein, J. Cooke, 2009, Vascular medicine.

Using plasma proteomic analysis for venous thromboembolism risk stratification in patients with advanced gastrointestinal cancers.

P. Tsao, L. Hofmann, Haruka Itakura, 2012 .

Abstract 16004: Nicotine Accelerates the Expansion of Abdominal Aortic Aneurysms in Mice; A Potential Role for miR-21 and miR-26a

P. Tsao, M. McConnell, R. Dalman, 2010 .

From Zanius to ADMA: ADMA - a new ''adipocytokine'' and its potential role in metabolic syndrome.

P. Tsao, J. Kielstein, 2007, JN. Journal of Nephrology (Milano. 1992).

Magnetic resonance imaging of progressive cardiomyopathic changes in the db/db mouse.

Ahmad Y. Sheikh, P. Tsao, E. Ashley, 2007, American journal of physiology. Heart and circulatory physiology.

Reduced myocardial brain natriuretic peptide expression and collagen deposition following ventricular assist device support for heart failure

P. Tsao, A. Connolly, M. Fowler, 2003 .

Felodipine Inhibits Intimal Lesion Formation in the Hypercholesterolemic Rabbit: Differential Effects on Endothelial and Monocyte Determinants of Atherogenesis

P. Tsao, J. Cooke, J. Niebauer, 1996, Vascular medicine.

Effects of felodipine on vascular structure, function and monocyte-endothelial interaction in the hypercholesterolemic rabbit

P. Tsao, J. Cooke, J. Niebauer, 1996 .

The role of endothelial dysfunction in restenosis.

P. Tsao, J. Cooke, 1992, Revista Portuguesa de Cardiologia.

2022 ACC/AHA guideline for the diagnosis and management of aortic disease: A report of the American Heart Association/American College of Cardiology Joint Committee on Clinical Practice Guidelines.

Dave L Dixon, P. Tsao, B. Gorenek, 2023, The Journal of thoracic and cardiovascular surgery.

Extracellular Delivery of Functional Mitochondria Rescues the Dysfunction of CD4+ T Cells in Aging

P. Tsao, H. Zhang, Hong Cai, 2021, bioRxiv.

Human internal mammary artery (IMA) transplantation and stenting: a human model to study the development of in-stent restenosis.

P. Tsao, E. Michelakis, R. Erben, 2012, Journal of visualized experiments : JoVE.

Insulin resistance is associated with a modest increase in inflammation in subcutaneous adipose tissue of moderately obese women

A. Sherman, A. J. Connolly, P. Tsao, 2008, Diabetologia.

Author Correction: Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations

P. Tsao, Hongyu Zhao, J. Concato, 2019, Nature Communications.

Role of microRNAs on Blood Brain Barrier Dysfunction in Vascular Cognitive Impairment.

P. Tsao, J. Spin, Kensuke Toyama, 2017, Current drug delivery.

Abstract 314: H19 Induces Abdominal Aortic Aneurysm Development and Progression

P. Tsao, P. Eriksson, J. Roy, 2018 .

Poster session 2

Hugo A. Katus, V. V. Miroshnikova, Paolo Dario, 2004, EP Europace.

Preoperative Computed Tomography Angiography Reveals Leaflet-Specific Calcification and Excursion Patterns in Aortic Stenosis

Sachin B. Malik, P. Tsao, A. Marsden, 2021, Circulation. Cardiovascular imaging.

An epigenetic clock analysis of race/ethnicity, sex, and coronary heart disease

M. Levine, D. Absher, T. Assimes, 2016, Genome Biology.

Battle of the bulge: miR-195 versus miR-29b in aortic aneurysm.

P. Tsao, J. Spin, 2014, Circulation research.

Effects of stenting on adjacent vascular distensibility and neointima formation: role of nitric oxide

P. Tsao, A. Yeung, J. Cooke, 2001, Vascular medicine.

Protective actions of a leukotriene B4 antagonist in splanchnic ischemia and reperfusion in rats.

A. M. Lefer, P. Tsao, Xinliang Ma, 1991, American Journal of Physiology.

A multiancestry genome-wide association study of unexplained chronic ALT elevation as a proxy for nonalcoholic fatty liver disease with histological and radiological validation

Christopher D. Brown, Henry J. Lin, Yan V. Sun, 2022, Nature Genetics.

Transcription Factor Runx2 Promotes Aortic Fibrosis and Stiffness in Type 2 Diabetes Mellitus.

P. Tsao, G. Hasenfuss, M. Buerke, 2015, Circulation research.

Novel mechanism for endothelial dysfunction: dysregulation of dimethylarginine dimethylaminohydrolase.

P. Tsao, S. Adimoolam, M. Kimoto, 1999, Circulation.

Identification and validation of N-acetyltransferase 2 as an insulin sensitivity gene.

T. Assimes, P. Tsao, J. Pankow, 2016, The Journal of clinical investigation.

Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

Andrew D. Johnson, Peter K. Joshi, Sara M. Willems, 2018, Nature Genetics.

Loss of CDKN2B Promotes p53-Dependent Smooth Muscle Cell Apoptosis and Aneurysm Formation

Clint L. Miller, P. Tsao, E. Schadt, 2013, Arteriosclerosis, thrombosis, and vascular biology.

Segmental Aortic Stiffening Contributes to Experimental Abdominal Aortic Aneurysm Development

Alexander M. Zöllner, P. Tsao, E. Kuhl, 2015, Circulation.

Trans-ethnic association study of blood pressure determinants in over 750,000 individuals

Sara M. Willems, Jacob M. Keaton, Joshua C. Smith, 2018, Nature Genetics.

Author Correction: Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations

P. Tsao, Hongyu Zhao, J. Concato, 2019, Nature Communications.

Abstract 5551: Apelin is Necessary for the Maintenance of Insulin Sensitivity

P. Tsao, T. Quertermous, G. Reaven, 2009, Circulation.

Statin therapy: beyond cholesterol lowering and antiinflammatory effects.

P. Tsao, A. Yeung, 2002, Circulation.

Human Engineered Heart Muscles Engraft and Survive Long Term in a Rodent Myocardial Infarction Model.

Vincent C. Chen, P. Tsao, W. Zimmermann, 2015, Circulation research.

Abstract 239: Transcriptomic Profiling Maps Anatomically Patterned Subpopulations Among Single Embryonic Cardiac Cells

P. Tsao, S. Quake, J. Priest, 2017, Circulation Research.

DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases

Audrey Y. Chu, Min A. Jhun, S. Horvath, 2016, Genome Biology.

Segmental Aortic Stiffening Contributes to Experimental Abdominal Aortic Aneurysm Development Running title: Raaz et al.; Segmental aortic stiffening drives AAA formation

Alexander M. Zöllner, P. Tsao, J. Spin, 2015 .