D. Alkon

D. Alkon, A. Favit, T. Nelson, 1998, Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.

POTASSIUM CHANNELS AND INTERNAL CALCIUM RELEASE: RELEVANCE FOR MEMORY STORAGE AND ALZHEIMER'S DISEASE

D. Alkon, R. Etcheberrigaray, 1995 .

Artificial neural networks - oscillations, chaos, and sequence processing

Lipo Wang, Daniel L. Alkon, D. Alkon, 1993 .

Imaging of memory-specific changes in the distribution of protein kinase C in the hippocampus.

D L Alkon, D. Alkon, M. Anderson, 1989, Science.

ABNORMAL CHOLESTEROL PROCESSING IN ALZHEIMER'S DISEASE PATIENT'S FIBROBLASTS

D. Alkon, Wei⁃qin Zhao, L. Ravindranath, 2003 .

Impairment of phosphatase 2A contributes to the prolonged MAP kinase phosphorylation in Alzheimer's disease fibroblasts

D. Alkon, Wei⁃qin Zhao, Christina Feng, 2003, Neurobiology of Disease.

cAMP-induced Cytoskeleton Rearrangement Increases Calcium Transients through the Enhancement of Capacitative Calcium Entry*

D. Alkon, A. Favit, M. Grimaldi, 1999, The Journal of Biological Chemistry.

Prevention of β‐Amyloid Neurotoxicity by Blockade of the Ubiquitin—Proteasome Proteolytic Pathway

D. Alkon, A. Favit, M. Grimaldi, 2000, Journal of neurochemistry.

Protein kinase C stimulates HuD‐mediated mRNA stability and protein expression of neurotrophic factors and enhances dendritic maturation of hippocampal neurons in culture

D. Alkon, C. Lim, 2012, Hippocampus.

PKCε Activation Restores Loss of PKCε, Manganese Superoxide Dismutase, Vascular Endothelial Growth Factor, and Microvessels in Aged and Alzheimer’s Disease Hippocampus

D. Alkon, Huaixing Wang, J. Hongpaisan, 2022, Frontiers in Aging Neuroscience.

Physiological levels of β-amyloid increase tyrosine phosphorylation and cytosolic calcium

D. Alkon, T. Sunderland, N. Hirashima, 1995, Brain Research.

Reply to Trewavas et al. and Calvo and Trewavas.

D. Alkon, A. Draguhn, A. Murphy, 2020, Trends in plant science.

Bryostatin extends tPA time window to 6 h following middle cerebral artery occlusion in aged female rats.

D. Alkon, C. Rosen, J. Simpkins, 2015, European journal of pharmacology.

Cerebral ischemia-induced difference in sensitivity to depression and potential therapeutics in rats

D. Alkon, Miao‐kun Sun, 2013, Behavioural pharmacology.

Early regulation of membrane excitability by ras oncogene proteins.

D. Alkon, D. Lowy, M. Sakakibara, 1990, Biophysical journal.

Calcium and cAMP as Synarchic Messengers

D. Alkon, J. Neary, 1983 .

Protein synthesis required for long-term memory is induced by PKC activation on days before associative learning.

D. Alkon, H. Epstein, A. Kuzirian, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Protection against beta-amyloid-induced apoptosis by peptides interacting with beta-amyloid.

D. Alkon, T. Nelson, 2007, The Journal of biological chemistry.

Characterization of a GTP-binding protein implicated in both memory storage and interorganelle vesicle transport.

D. Alkon, T. Yoshioka, T. Nelson, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Associative neural and behavioral change in Hermissenda: consequences of nervous system orientation for light and pairing specificity.

D L Alkon, D. Alkon, J. Farley, 1982, Journal of neurophysiology.

VOLTAGE-DEPENDENT POTASSIUM CURRENT

D. Alkon, J. Shoukimas, 2005 .

Primary neural substrates of learning and behavioral change

Daniel L. Alkon, Joseph Farley, D. Alkon, 1984 .

Neural modification by paired sensory stimuli

D. Alkon, 1976, The Journal of general physiology.

Larval rearing, metamorphosis, growth and reproduction of the eolid nudibranch hermissenda crassicornis (eschscholtz, 1831) (gastropoda: opisthobranchia).

D. Alkon, J. Harrigan, 1978, The Biological bulletin.

Associative Training of Hermissenda

D. Alkon, 1974, The Journal of general physiology.

Alzheimer's Disease Cerebrospinal Fluid and Neuroimaging Biomarkers: Diagnostic Accuracy and Relationship to Drug Efficacy.

D. Alkon, T. Khan, 2015, Journal of Alzheimer's disease : JAD.

Role of insulin and insulin receptor in learning and memory

D. Alkon, Wei⁃qin Zhao, Wei-Qin Zhao, 2001, Molecular and Cellular Endocrinology.

Time windows for effects of protein synthesis inhibitors on Pavlovian conditioning in Hermissenda: Behavioral aspects

D. Alkon, H. Epstein, A. Kuzirian, 2003, Neurobiology of Learning and Memory.

Pavlovian conditioning-specific increases of the Ca2+- and GTP-binding protein, calexcitin in identified Hermissenda visual cells

D. Alkon, H. Epstein, A. Kuzirian, 2001, Journal of neurocytology.

Spatial learning induced changes in expression of the ryanodine type II receptor in the rat hippocampus

D. Alkon, D. Alkon, A. Quattrone, 2000, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Arachidonic acid and diacylglycerol act synergistically through protein kinase C to persistently enhance synaptic transmission in the hippocampus

D. Alkon, C. Bramham, D. Lester, 1994, Neuroscience.

Outgrowths fromHermissenda photoreceptor somata are associated with activation of protein kinase C

D. Alkon, L. Matzel, I. Lederhendler, 1990, Brain Research.

Quantitative distribution of protein kinase C α, β, γ, and ϵ mRNAS in the hippocampus of control and nictitating membrane conditioned rabbits

D. Alkon, B. Schreurs, A. Scharenberg, 1993 .

C-kinase activation prolongs Ca2+-dependent inactivation of K+ currents.

D. Alkon, J. Neary, H. Rasmussen, 1986, Biochemical and biophysical research communications.

Learning and memory

Lucien T. Thompson, B. McNaughton, M. Mishkin, 1991, Brain Research Reviews.

Ryanodine receptor modulation of in vitro associative learning in Hermissenda crassicornis

Kim T Blackwell, D. Alkon, K. Blackwell, 1999, Brain Research.

Biological plausibility of artificial neural networks: learning by non-Hebbian synapses

Kim T. Blackwell, Thomas P. Vogl, Daniel L. Alkon, 1993 .

Biological plausibility of synaptic associative memory models

Kim T. Blackwell, Thomas P. Vogl, Garth S. Barbour, 1994, Neural Networks.

The interstimulus interval and classical conditioning in the marine snail Hermissenda crassicornis

Daniel L. Alkon, D. Alkon, I. Lederhendler, 1989, Behavioural Brain Research.

Classical conditioning and protein kinase C activation regulate the same single potassium channel in Hermissenda crassicornis photoreceptors.

D. Alkon, L. Matzel, I. Lederhendler, 1992, Proceedings of the National Academy of Sciences of the United States of America.

A Model Of Associative Learning In Hermissenda Crassicornis: Sensitin'ities To Temporal Relationships Of Stimuli

T. P. Vogl, D. Alkon, K. Blackwell, 1991, Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society Volume 13: 1991.

GABA-induced potentiation of neuronal excitability occurs during contiguous pairings with intracellular calcium elevation

D. Alkon, L. Matzel, 1991, Brain Research.

A MODEL OF ASSOCIATIVE LEARNING IN J-E- A CRASSICORN IS: SENSITIVITIES TO TEMPORAL RELATIONSHIPS OF STIMULI

T. P. Vogl, D. Alkon, K. Blackwell, 1991 .

Sequential changes of potassium currents in Hermissenda Type B photoreceptor during early stages of classical conditioning

Daniel L. Alkon, Carlos Collin, D. Alkon, 1990, Neuroscience Letters.

Associatively reduced withdrawal from shadows in Hermissenda: a direct behavioral analog of photoreceptor responses to brief light steps.

D. Alkon, I. Lederhendler, 1987, Behavioral and neural biology.

Sensory, interneuronal, and motor interactions within Hermissenda visual pathway.

D L Alkon, D. Alkon, Y Goh, 1984, Journal of neurophysiology.

Primary changes of voltage responses during retention of associative learning.

D L Alkon, D. Alkon, A West, 1982, Journal of neurophysiology.

Positive synaptic feedback in visual system of nudibranch mollusk Hermissenda crassicornis.

D. Alkon, M. Tabata, 1982, Journal of neurophysiology.

Associative Behavioral Modification in Hermissenda: Cellular Correlates

D. Alkon, T. Crow, D. L. Alkon, 1980, Science.

Long-lasting depolarization and hyperpolarization in eye of Hermissenda.

D. Alkon, Y. Grossman, 1978, Journal of neurophysiology.

Extinction of associative learning in Hermissenda: Behavior and neural correlates

Daniel L. Alkon, Joseph Farley, D. Alkon, 1984, Behavioural Brain Research.

Learning-induced activation of protein kinase C

D. Alkon, J. Loturco, B. Bank, 1989, Molecular Neurobiology.

Biophysical and behavioral correlates of memory storage, degradation, and reactivation.

D L Alkon, D. Alkon, C. Collin, 1992, Behavioral neuroscience.

Acquisition of conditioned associations in Hermissenda: additive effects of contiguity and the forward interstimulus interval.

D L Alkon, B G Schreurs, D. Alkon, 1990, Behavioral neuroscience.

Neural Mechanisms of Conditioning

C. Woody, D. Alkon, 2011, Springer US.

Changes of Membrane Currents and Calcium-Dependent Phosphorylation during Associative Learning

D. Alkon, 1986 .

Calcium-mediated decrease of a voltage-dependent potassium current.

D L Alkon, D. Alkon, J. Shoukimas, 1982, Biophysical journal.

Neural organization predicts stimulus specificity for a retained associative behavioral change.

D. Alkon, J. Farley, 1980, Science.

Calcium responses in human fibroblasts: A diagnostic molecular profile for Alzheimer's disease

Daniel L. Alkon, Giuliano Binetti, Marco Racchi, 1996, Neurobiology of Aging.

Peripheral biomarkers of Alzheimer's disease.

D. Alkon, Daniel L Alkon, T. Khan, 2015, Journal of Alzheimer's disease : JAD.

MAP Kinase Signaling Cascade Dysfunction Specific to Alzheimer's Disease in Fibroblasts

D. Alkon, C. Lyketsos, Wei⁃qin Zhao, 2002, Neurobiology of Disease.

Calcium Responses in Fibroblasts from Asymptomatic Members of Alzheimer's Disease Families

D. Alkon, R. Tanzi, M. Racchi, 1998, Neurobiology of Disease.

Peripheral markers in testing pathophysiological hypotheses and diagnosing Alzheimer's disease

D. Alkon, J. Blass, M. Trabucchi, 1998, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Potassium Channels and Calcium Release

D. Alkon, R. Etcheberrigaray, 1997 .

Alzheimer and beta-amyloid-treated fibroblasts demonstrate a decrease in a memory-associated GTP-binding protein, Cp20.

D. Alkon, T. Yoshioka, J. Olds, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Use of Cultured Fibroblasts in Elucidating the Pathophysiology and Diagnosis of Alzheimer's Disease a

D. Alkon, R. Martins, J. Blass, 1994, Annals of the New York Academy of Sciences.

Soluble beta-amyloid induction of Alzheimer's phenotype for human fibroblast K+ channels.

D L Alkon, D. Alkon, E. Ito, 1994, Science.

Potassium channel dysfunction in fibroblasts identifies patients with Alzheimer disease.

D. Alkon, K. Oka, G. Gibson, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Isolation of a G protein that is modified by learning and reduces potassium currents in Hermissenda.

D L Alkon, D. Alkon, C. Collin, 1990, Science.

Memory Traces in the Brain

Daniel L. Alkon, D. Alkon, 1987 .

Effects of noise in training patterns on the diluted Hopfield neural network

Lipo Wang, Daniel L. Alkon, D. Alkon, 1993 .

Processing temporal sequences with a biologically-based artificial network

Lipo Wang, Daniel L. Alkon, D. Alkon, 1993 .

Bryostatin Effects on Cognitive Function and PKCɛ in Alzheimer’s Disease Phase IIa and Expanded Access Trials

Daniel L. Alkon, Thomas J. Nelson, D. Alkon, 2017, Journal of Alzheimer's disease : JAD.

Bryostatin Placebo-Controlled Trials Indicate Cognitive Restoration Above Baseline for Advanced Alzheimer’s Disease in the Absence of Memantine

D. Alkon, A. Tuchman, Richard E. Thompson, 2022, Journal of Alzheimer's disease : JAD.

Neuro-regeneration Therapeutic for Alzheimer's Dementia: Perspectives on Neurotrophic Activity.

D. Alkon, Miao‐kun Sun, 2019, Trends in pharmacological sciences.

REPLICATION TRIAL TO CONFIRM REVERSAL OF COGNITIVE DECLINE WITH BRYOSTATIN FOR ADVANCED ALZHEIMER’S PATIENTS IN THE ABSENCE OF MEMANTINE

Richard E Thompson, D. Alkon, Lee-Jen Wei, 2019, Alzheimer's & Dementia.

SIGNIFICANT COGNITIVE IMPROVEMENT WITH BRYOSTATIN FOR ADVANCED ALZHEIMER’S PATIENTS IN THE ABSENCE OF MEMANTINE

Richard E Thompson, D. Alkon, Lee-Jen Wei, 2018, Alzheimer's & Dementia.

Rescue of Synaptic Phenotypes and Spatial Memory in Young Fragile X Mice

D. Alkon, Miao‐kun Sun, J. Hongpaisan, 2016, The Journal of Pharmacology and Experimental Therapeutics.

Molecular regulation of synaptogenesis during associative learning and memory

D. Alkon, T. Nelson, 2015, Brain Research.

Towards universal therapeutics for memory disorders.

D. Alkon, Miao‐kun Sun, T. Nelson, 2015, Trends in pharmacological sciences.

Identification of the PS1 Thr147Ile Variant in a Family with Very Early Onset Dementia and Expressive Aphasia

D. Alkon, B. Schreurs, Jun Fan, 2015, Journal of Alzheimer's disease : JAD.

ApoE4 and Aβ Oligomers Reduce BDNF Expression via HDAC Nuclear Translocation

D. Alkon, T. Nelson, Abhik Sen, 2015, The Journal of Neuroscience.

PKCε deficits in Alzheimer's disease brains and skin fibroblasts.

D. Alkon, T. Nelson, T. Khan, 2014, Journal of Alzheimer's disease : JAD.

Bryostatin-1 Restores Hippocampal Synapses and Spatial Learning and Memory in Adult Fragile X Mice

D. Alkon, Miao‐kun Sun, C. Lim, 2014, The Journal of Pharmacology and Experimental Therapeutics.

PKCε Promotes HuD-Mediated Neprilysin mRNA Stability and Enhances Neprilysin-Induced Aβ Degradation in Brain Neurons

D. Alkon, C. Lim, 2014, PloS one.

PKC activation during training restores mushroom spine synapses and memory in the aged rat

D. Alkon, Changqing Xu, T. Nelson, 2013, Neurobiology of Disease.

Apolipoprotein E3 (ApoE3) but Not ApoE4 Protects against Synaptic Loss through Increased Expression of Protein Kinase Cϵ

D. Alkon, T. Nelson, Abhik Sen, 2012, The Journal of Biological Chemistry.

PKC ε Activation Prevents Synaptic Loss, Aβ Elevation, and Cognitive Deficits in Alzheimer's Disease Transgenic Mice

D. Alkon, Miao‐kun Sun, J. Hongpaisan, 2011, The Journal of Neuroscience.

Protein Kinase C Activators as Synaptogenic and Memory Therapeutics

D. Alkon, Miao‐kun Sun, Miao-Kun Sun, 2009, Archiv der Pharmazie.

Reduction of β-Amyloid Levels by Novel Protein Kinase Cϵ Activators

D. Alkon, Yuan Luo, C. Cui, 2009, The Journal of Biological Chemistry.

A structural basis for enhancement of long-term associative memory in single dendritic spines regulated by PKC

D. Alkon, J. Hongpaisan, 2007, Proceedings of the National Academy of Sciences.

Bryostatin Enhancement of Memory in Hermissenda

D. Alkon, H. Epstein, M. Sakakibara, 2006, The Biological Bulletin.

Conservation of Cellular Mechanisms for Models of Learning and Memory

Daniel L. Alkon, D. Alkon, 1988 .

Transient and Persistent Depolarization‐Induced Changes of Protein Phosphorylation in a Molluscan Nervous System

D. Alkon, S. Naito, B. Bank, 1988, Journal of neurochemistry.

Ca2+/Diacylglycerol‐Activated, Phospholipid‐Dependent Protein Kinase in the Hermissenda CNS

D. Alkon, J. Neary, S. Naito, 1986, Journal of neurochemistry.

Modulation of calcium-mediated inactivation of ionic currents by Ca2+/calmodulin-dependent protein kinase II.

D. Alkon, J. Neary, M. Sakakibara, 1986, Biophysical journal.

Biochemical mechanisms of memory storage.

D. Alkon, S. Naito, 1986, Journal de physiologie.

Depolarization-induced effects of Ca2+-calmodulin-dependent protein kinase injection, in vivo, in single neurons of cat motor cortex

C. Woody, D. Alkon, B. Hay, 1984, Brain Research.

Light- and voltage-dependent increases of calcium ion concentration in molluscan photoreceptors.

D L Alkon, D. Alkon, J Connor, 1984, Journal of neurophysiology.

Change in a specific phosphoprotein band following associative learning in Hermissenda

D. Alkon, T. Crow, J. Neary, 1981, Nature.

Cellular memory in an invertebrate

D. Alkon, D. Lester, P. Huddie, 1992 .

Biochemistry of molluscan learning and memory

D. Alkon, T. Nelson, Daniel L. Alkon, 1997 .

Bryostatin-1 Restores Blood Brain Barrier Integrity following Blast-Induced Traumatic Brain Injury

D. Alkon, C. Rosen, B. Lucke-Wold, 2015, Molecular Neurobiology.

Synergistic effects of chronic bryostatin-1 and alpha-tocopherol on spatial learning and memory in rats.

D. Alkon, Miao‐kun Sun, 2008, European journal of pharmacology.

Signal transformation with pairing of sensory stimuli

D. Alkon, 1976, The Journal of general physiology.

Arachidonic acid and diacylglycerol act synergistically to activate protein kinase C in vitro and in vivo.

D L Alkon, D. Alkon, C. Collin, 1991, Biochemical and biophysical research communications.

Fluorophors formed from imidazoles.

D. Alkon, J. Green, K. Liao, 1971, Analytical biochemistry.

Activation of protein kinase C isozymes for the treatment of dementias.

D. Alkon, Miao‐kun Sun, Miao-Kun Sun, 2012, Advances in pharmacology.

Pharmacology of protein kinase C activators: cognition-enhancing and antidementic therapeutics.

D. Alkon, Miao‐kun Sun, 2010, Pharmacology & therapeutics.

Classical conditioning induces long-term translocation of protein kinase C in rabbit hippocampal CA1 cells.

D. Alkon, H. Rasmussen, A. Kuzirian, 1988, Proceedings of the National Academy of Sciences of the United States of America.

Protein Kinase Cϵ (PKCϵ) Promotes Synaptogenesis through Membrane Accumulation of the Postsynaptic Density Protein PSD-95*

D. Alkon, T. Nelson, Abhik Sen, 2016, The Journal of Biological Chemistry.

PKC epsilon Promotes Synaptogenesis through Membrane Accumulation of the Postsynaptic Density Protein PSD-95

D. Alkon, T. Nelson, Abhik Sen, 2016 .

Signaling Pathways Involved in Cognitive Enhancement

D. Alkon, Miao‐kun Sun, T. Nelson, 2015 .

Protein kinase C mediates memory consolidation of taste avoidance conditioning in Lymnaea stagnalis

D. Alkon, M. Sakakibara, K. Lukowiak, 2014, Neurobiology of Learning and Memory.

PKC activator therapeutic for mild traumatic brain injury in mice

D. Alkon, T. Nelson, C. Pick, 2011, Neurobiology of Disease.

PKC and Insulin Pathways in Memory Storage: Targets for Synaptogenesis, Anti-apoptosis, and the Treatment of AD

D. Alkon, Miao‐kun Sun, T. Nelson, 2010 .

Postischemic PKC activation rescues retrograde and anterograde long-term memory

D. Alkon, Miao‐kun Sun, J. Hongpaisan, 2009, Proceedings of the National Academy of Sciences.

Insulin, PKC signaling pathways and synaptic remodeling during memory storage and neuronal repair.

D. Alkon, Miao‐kun Sun, T. Nelson, 2008, European journal of pharmacology.

GTP-binding proteins and potassium channels involved in synaptic plasticity and learning

D. Alkon, T. Nelson, 2008, Molecular Neurobiology.

Dual effects of bryostatin-1 on spatial memory and depression.

D. Alkon, Miao‐kun Sun, Miao-Kun Sun, 2005, European journal of pharmacology.

Pattern-recognition by an artificial network derived from biologic neuronal systems

A. K. Rigler, T. P. Vogl, D. L. Alkon, 1990, Biological Cybernetics.

Hippocampal protein‐protein interactions in spatial memory

D. Alkon, T. Nelson, Peter S Backlund, 2004, Hippocampus.

Imaging learning and memory: Classical conditioning

D L Alkon, B G Schreurs, D. Alkon, 2001, The Anatomical record.

Time domains of neuronal Ca2+ signaling and associative memory: steps through a calexcitin, ryanodine receptor, K+ channel cascade

Sebastiano Cavallaro, Thomas J Nelson, D. Alkon, 1998, Trends in Neurosciences.

Molecular specificity of synaptic changes responsible for associative memory.

D L Alkon, D. Alkon, 1998, Advances in experimental medicine and biology.

Calexcitin: a signaling protein that binds calcium and GTP, inhibits potassium channels, and enhances membrane excitability.

D L Alkon, B G Schreurs, D. Alkon, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Protein kinase C in the hippocampus is altered by spatial but not cued discriminations: A component task analysis

M. Mishkin, D. Alkon, D. Olton, 1995, Brain Research.

Lateralization of membrane-associated protein kinase C in rat piriform cortex: Specific to operant training cues in the olfactory modality

James M. Bower, Upinder S. Bhalla, Daniel L. Alkon, 1994, Behavioural Brain Research.

Gated informational transfer within the mammalian hippocampus: a new hypothesis

D. Alkon, J. Olds, J. Sánchez-Andrés, 1993, Behavioural Brain Research.

Neural Correlates of Memory Storage

D. Alkon, C. Collin, 1992 .

Activation of protein kinase C phosphorylation pathways: a role for storage of associative memory.

D. Alkon, D. Lester, 1991, Progress in brain research.

Specificity of molecular changes in neurons involved in memory storage

D. Alkon, T. Nelson, 1990, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Specific protein changes during memory acquisition and storage

D L Alkon, D. Alkon, T J Nelson, 1989, BioEssays : news and reviews in molecular, cellular and developmental biology.

THE PHYSICAL REALITY OF MEMORY

D. Alkon, J. Olds, T. Nelson, 1989 .

Reduction of two voltage-dependent K+ currents mediates retention of a learned association.

D L Alkon, D. Alkon, I. Lederhendler, 1985, Behavioral and neural biology.

Analysis of long-term cognitive-enhancing effects of bryostatin-1 on the rabbit (Oryctolagus cuniculus) nictitating membrane response

D. Alkon, B. Schreurs, Desheng Wang, 2008, Behavioural pharmacology.

Pavlovian conditioning of distinct components of Hermissenda's responses to rotation.

D L Alkon, B G Schreurs, D. Alkon, 1990, Behavioral and neural biology.

PKC activators enhance GABAergic neurotransmission and paired-pulse facilitation in hippocampal CA1 pyramidal neurons

D. Alkon, Q.-Y. Liu, C. Xu, 2014, Neuroscience.

Common mechanisms of Alzheimer's disease and ischemic stroke: the role of protein kinase C in the progression of age-related neurodegeneration.

D. Alkon, C. Rosen, J. Simpkins, 2014, Journal of Alzheimer's disease : JAD.

PKC signaling deficits: a mechanistic hypothesis for the origins of Alzheimer's disease.

D. Alkon, Miao‐kun Sun, T. Nelson, 2007, Trends in pharmacological sciences.

Motile statocyst cilia transmit rather than directly transduce mechanical stimuli

D. Alkon, E. Stommel, R. Stephens, 1980, The Journal of cell biology.

Induction of photoresponse by the hydrolysis of polyphosphoinositides in the Hermissenda type B photoreceptor.

D L Alkon, D. Alkon, T. Yoshioka, 1994, Biochemical and biophysical research communications.

Regulation of Ca2+ stores in glial cells

D. Alkon, G. Scapagnini, T. Nelson, 2003 .

A new approach to hand-written character recognition

Kim T. Blackwell, Thomas P. Vogl, Garth S. Barbour, 1992, Pattern Recognit..

Gene expression profiles of apoptotic neurons.

D. Alkon, M. Ciotti, S. Cavallaro, 2004, Genomics.

Insulin receptor signaling in long-term memory consolidation following spatial learning.

D. Alkon, Wei⁃qin Zhao, J. Dou, 2005, Learning & memory.

Pharmacological enhancement of synaptic efficacy, spatial learning, and memory through carbonic anhydrase activation in rats.

D. Alkon, M. Sun, 2001, The Journal of pharmacology and experimental therapeutics.

Protection against β-Amyloid-induced Apoptosis by Peptides Interacting with β-Amyloid*

D. Alkon, T. Nelson, 2007, Journal of Biological Chemistry.

Early diagnostic accuracy and pathophysiologic relevance of an autopsy-confirmed Alzheimer's disease peripheral biomarker

D. Alkon, T. Khan, 2010, Neurobiology of Aging.

Induced depressive behavior impairs learning and memory in rats

D. Alkon, M. Sun, 2004, Neuroscience.

Orange Juice Classification with a Biologically Based Neural Network

Kim T. Blackwell, Thomas P. Vogl, Garth S. Barbour, 1996, Comput. Chem..

Synergistic activation of protein kinase C by arachidonic acid and diacylglycerols in vitro: generation of a stable membrane-bound, cofactor-independent state of protein kinase C activity.

D L Alkon, D. Alkon, D. Lester, 1996, Biochimica et biophysica acta.

Posttranscriptional regulation of gene expression in learning by the neuronal ELAV-like mRNA-stabilizing proteins

D. Alkon, P. Gusev, A. Quattrone, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Time-resolved imaging of protein kinase C activation during sea urchin egg fertilization.

D. Alkon, S. Kawahara, Y. Kirino, 1997, Experimental cell research.

Differential Gender-Related Vulnerability to Depression Induction and Converging Antidepressant Responses in Rats

D. Alkon, Miao‐kun Sun, Miao-Kun Sun, 2006, Journal of Pharmacology and Experimental Therapeutics.

An artificial neural network system for temporal-spatial sequence processing

Lipo Wang, Daniel L. Alkon, D. Alkon, 1995, Pattern Recognit..

An internally controlled peripheral biomarker for Alzheimer’s disease: Erk1 and Erk2 responses to the inflammatory signal bradykinin

D. Alkon, T. Khan, 2006, Proceedings of the National Academy of Sciences.

Ionic conductance determinants of synaptic memory nets and their implications for Alzheimer's disease

D. Alkon, 1999, Journal of neuroscience research.

Regional Rat Brain Distribution of Heme Oxygenase-1 and Manganese Superoxide Dismutase mRNA: Relevance of Redox Homeostasis in the Aging Processes

D. Alkon, V. Calabrese, G. Scapagnini, 2003, Experimental biology and medicine.

Cholesterol-enriched diet affects spatial learning and synaptic function in hippocampal synapses

D. Alkon, M. Atzori, P. Gusev, 2006, Brain Research.

"Either-or" two-slit interference: stable coherent propagation of individual photons through separate slits.

D. Alkon, D. L. Alkon, 2001, Biophysical journal.

Bryostatin-1 Restores Blood Brain Barrier Integrity following Blast-Induced Traumatic Brain Injury

D. Alkon, C. Rosen, B. Lucke-Wold, 2015, Molecular Neurobiology.

Translocation of protein kinase C‐βII in astrocytes requires organized actin cytoskeleton and is not accompanied by synchronous RACK1 relocation

D. Alkon, A. Pascale, M. Grimaldi, 2004, Glia.

Conditioning-Specific Biophysical Alterations in Rabbit Hippocampus

D. Alkon, J. Disterhoft, D. Coulter, 1988 .

GABA‐Mediated Synaptic Interaction Between the Visual and Vestibular Pathways of Hermissenda

D. Alkon, L. Matzel, I. Kapetanovic, 1993, Journal of neurochemistry.

Effects of α2‐Adrenergic Agonists and Antagonists on Photoreceptor Membrane Currents

D. Alkon, I. Lederhendler, M. Sakakibara, 1987 .

INDIVIDUAL VARIATION IN ASSOCIATIVE LEARNING OF THE NUDIBRANCH MOLLUSC HERMISSENDA CRASSICORNIS

D. Alkon, J. Harrigan, 1985 .

Voltage-dependent calcium and calcium-activated potassium currents of a molluscan photoreceptor.

D L Alkon, D. Alkon, J. Farley, 1984, Biophysical journal.

Protein kinase injection reduces voltage-dependent potassium currents.

D. Alkon, J. Acosta-Urquidi, J. Neary, 1983, Science.

Cholinergic features of photoreceptor synapses in Hermissenda.

D. Alkon, Y. Grossman, E. Heldman, 1979, Journal of neurophysiology.

Long-term synergistic regulation of ionic channels by C-kinase and Ca2+/CaM-type II kinase.

D. Alkon, S. Naito, 1987, Advances in experimental medicine and biology.

BEHAVIORAL, ELECTROPHYSIOLOGICAL, AND MORPHOLOGICAL INVESTIGATIONS OF STATOCYST FUNCTION IN THE NUDIBRANCH MOLLUSC HERMISSENDA CRASSICORNIS

D. Alkon, T. Crow, A. Kuzirian, 1986 .

A Biophysical Basis for Molluscan Associative Learning

D. Alkon, 1982 .

Membrane Channels, Conditioning-Induced Changes

D. Alkon, 1988 .

Protein kinase C substrate activators: potential as novel antidepressants

D. Alkon, Miao‐kun Sun, Miao-Kun Sun, 2005 .

Conditioning-specific modification of the rabbit's unconditioned nictitating membrane response.

D L Alkon, B G Schreurs, D. Alkon, 1995, Behavioral neuroscience.

GABA-induced responses in Purkinje cell dendrites of the rabbit cerebellar slice

D. Alkon, B. Schreurs, J. Sánchez-Andrés, 1992, Brain Research.

Different ionic conductances are modulated during the late receptor potential and the prolonged depolarizing afterpotential in Hermissenda type A photoreceptors

D. Alkon, H. Höpp, 1993, Journal of Comparative Physiology A.

Intracellular correlates of spatial memory acquisition in hippocampal slices: long-term disinhibition of CA1 pyramidal cells.

D. Alkon, P. Gusev, 2001, Journal of neurophysiology.

Cerebral hypoperfusion and amyloid-induced synergistic impairment of hippocampal CA1 synaptic efficacy and spatial memory in young adult rats.

D. Alkon, Miao‐kun Sun, 2004, Journal of Alzheimer's Disease.

Pharmacological protection of synaptic function, spatial learning, and memory from transient hypoxia in rats.

D. Alkon, Miao‐kun Sun, Hui Xu, 2002, The Journal of pharmacology and experimental therapeutics.

Enhancement of long-term memory retention and short-term synaptic plasticity in cbl-b null mice.

D. Alkon, N. Koshiya, Hua Gu, 2006, Proceedings of the National Academy of Sciences of the United States of America.

Functional switching of GABAergic synapses by ryanodine receptor activation.

D. Alkon, M. Sun, T. Nelson, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Inhibition of coactivator-associated arginine methyltransferase 1 modulates dendritic arborization and spine maturation of cultured hippocampal neurons

D. Alkon, C. Lim, 2017, The Journal of Biological Chemistry.

Differential expression of heme oxygenase isoforms in rat brain by endotoxin (LPS)

D. Alkon, N. Abraham, V. Calabrese, 2003 .

Morphometric imaging biomarker identifies Alzheimer’s disease even among mixed dementia patients

D. Alkon, J. Brandt, G. Nebe-von-Caron, 2022, Scientific Reports.

Reconstruction of ionic currents in a molluscan photoreceptor.

S Usui, D L Alkon, D. Alkon, 1993, Biophysical journal.

Theta rhythm of hippocampal CA1 neuron activity: gating by GABAergic synaptic depolarization.

D. Alkon, M. Sun, T. Nelson, 2001, Journal of neurophysiology.

Plants Neither Possess nor Require Consciousness.

D. Alkon, A. Draguhn, A. Murphy, 2019, Trends in plant science.

Gene expression profiles of heme oxygenase isoforms in the rat brain

D. Alkon, S. Cavallaro, V. D’Agata, 2002, Brain Research.

Gene Expression Profiles in a Transgenic Animal Model of Fragile X Syndrome

D. Alkon, S. Warren, Wei⁃qin Zhao, 2002, Neurobiology of Disease.

Memory-specific temporal profiles of gene expression in the hippocampus

D. Alkon, S. Cavallaro, V. D’Agata, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Impairment of Hippocampal CA1 Heterosynaptic Transformation and Spatial Memory by β-Amyloid25–35

D. Alkon, Miao‐kun Sun, Miao-Kun Sun, 2002 .

Impairment of Hippocampal CA 1 Heterosynaptic Transformation and Spatial Memory by-Amyloid 25 – 35

D. Alkon, Miao‐kun Sun, Miao-Kun Sun, 2002 .

Impairment of hippocampal CA1 heterosynaptic transformation and spatial memory by beta-amyloid(25-35).

D. Alkon, Miao‐kun Sun, Miao-Kun Sun, 2002, Journal of neurophysiology.

Increase of the RNA-binding protein HuD and posttranscriptional up-regulation of the GAP-43 gene during spatial memory.

D. Alkon, P. Gusev, A. Quattrone, 2004, Proceedings of the National Academy of Sciences of the United States of America.

A role for protein kinase C in associative learning.

D. Alkon, J. Olds, 1991, The New biologist.

Neurotransmitter synthesis in the nervous system of the mollusc Hermissenda.

D. Alkon, E. Heldman, 1978, Comparative biochemistry and physiology. C: Comparative pharmacology.

Cellular Mechanisms of Classical Conditioning

Bernard G. Schreurs, Daniel L. Alkon, D. Alkon, 2002 .

Calexcitin interaction with neuronal ryanodine receptors.

D L Alkon, D. Alkon, L. Pozzo-Miller, 1999, The Biochemical journal.

Mapping membrane potential transients in crayfish (Procambarus clarkii) optic lobe neuropils with voltage-sensitive dyes.

D L Alkon, D. Alkon, D. Sattelle, 1999, Journal of neurophysiology.

Alzheimer's-specific effects of soluble beta-amyloid on protein kinase C-alpha and -gamma degradation in human fibroblasts.

D. Alkon, A. Favit, T. Nelson, 1998, Proceedings of the National Academy of Sciences of the United States of America.

A method for measuring nanogram quantities of acetylcholine by pyrolysis-gas chromatography: the demonstration of acetylcholine in effluents from the rat phrenic nerve-diaphragm preparation.

D. Alkon, J. Green, D. Schmidt, 1970, Journal of Pharmacology and Experimental Therapeutics.

Programs of Gene Expression During the Laying Down of Memory Formation as Revealed by DNA Microarrays

D. Alkon, S. Cavallaro, V. D’Agata, 2002, Neurochemical Research.

Gene expression profiles during long‐term memory consolidation

D. Alkon, B. Schreurs, S. Cavallaro, 2001, The European journal of neuroscience.

Behavioral effects of dietary cholesterol in rats tested in experimental models of mild stress and cognition tasks

D. Alkon, F. Drago, G. Scapagnini, 2008, European Neuropsychopharmacology.

New developments in the search for a cure.

D. Alkon, 2011, West Virginia Medical Journal.

AHP reductions in rabbit hippocampal neurons during conditioning correlate with acquisition of the learned response

D. Alkon, H. Read, J. Disterhoft, 1988, Brain Research.

Protein kinase C redistribution within CA3 stratum oriens during acquisition of nictitating membrane conditioning in the rabbit.

D. Alkon, B. Schreurs, A. Scharenberg, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Links between Alzheimer's disease and diabetes.

D. Alkon, Miao‐kun Sun, 2006, Drugs of today.

Identification of faces obscured by noise: comparison of an artificial neural network with human observers

Michael A. Brown, Kim T. Blackwell, Thomas P. Vogl, 1997, J. Exp. Theor. Artif. Intell..

The role of neurochemical modulation in learning

D. Alkon, I. Lederhendler, M. Sakakibara, 1986, Neuroscience Research.

Secretion of Annexin II via Activation of Insulin Receptor and Insulin-like Growth Factor Receptor*

D. Alkon, Hui Chen, M. Quon, 2003, The Journal of Biological Chemistry.

Complex responses to light of the nudibranch Hermissenda crassicornis (Gastropoda: opisthobranchia)

D. Alkon, I. Lederhendler, E. Barnes, 1980 .

Insulin and cholesterol pathways in neuronal function, memory and neurodegeneration.

D L Alkon, Artur Emílio S. Reis, D. Alkon, 2005, Biochemical Society transactions.

Age‐dependent enhancement of inhibitory synaptic transmission in CA1 pyramidal neurons via GluR5 kainate receptors

D. Alkon, Changqing Xu, Daniel L. Alkon, 2009, Hippocampus.

Molecular mechanisms of associative memory and their clinical implications

Daniel L. Alkon, D. Alkon, 1995, Behavioural Brain Research.

Internal Ca 2 + mobilization is altered in fibroblasts from patients with Alzheimer disease

D. Alkon, K. Oka, D. McPhie, 2005 .

ApoE isoforms differentially regulates cleavage and secretion of BDNF

D. Alkon, T. Nelson, Abhik Sen, 2017, Molecular Brain.

TNF‐α induced over‐expression of GFAP is associated with MAPKs

D. Alkon, D. Rubinow, J. Barker, 2000, Neuroreport.

Isolation of Protein Subpopulations Undergoing Protein-Protein Interactions*

D. Alkon, A. Yergey, P. Backlund, 2002, Molecular & Cellular Proteomics.

Associative learning potentiates protein kinase C activation in synaptosomes of the rabbit hippocampus.

D. Alkon, B. Schreurs, D. Lester, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Enhancement of synaptic potentials in rabbit CA1 pyramidal neurons following classical conditioning.

D L Alkon, D. Alkon, D. Coulter, 1988, Proceedings of the National Academy of Sciences of the United States of America.

Responses of hair cells to statocyst rotation

D. Alkon, 1975, The Journal of general physiology.

Gene expression of α‐endosulfine in the rat brain: correlative changes with aging, learning and stress

D. Alkon, Wei⁃qin Zhao, J. Dou, 2003, Journal of neurochemistry.

Thermal imaging of receptor-activated heat production in single cells.

D L Alkon, D. Alkon, T. Yoshioka, 1998, Biophysical journal.

Responses of Photoreceptors in Hermissenda

Daniel L. Alkon, M. Fuortes, D. Alkon, 1972, The Journal of general physiology.

An infraciliary network in statocyst hair cells

D. Alkon, A. Kuzirian, L. Harris, 1981, Journal of neurocytology.

Autoradiographic measurement of tritiated agmatine as an indicator of physiologic activity inHermissenda visual and vestibular neurons

D. Alkon, J. Neary, E. Meyhöfer, 1986, Journal of neurocytology.

Contraction of neuronal branching volume: an anatomic correlate of Pavlovian conditioning.

D. Alkon, B. Schreurs, L. Matzel, 1990, Proceedings of the National Academy of Sciences of the United States of America.

Contraction ofneuronal branching volume: Ananatomic correlate ofPavlovian conditioning

D. Alkon, B. Schreurs, L. Matzel, 1990 .

Effects of age on susceptibility to the induction of depressive behavior and imipramine in rats

D. Alkon, Miao‐kun Sun, 2008, Behavioural pharmacology.

Stress: perspectives on its impact on cognition and pharmacological treatment

D. Alkon, Miao‐kun Sun, 2014, Behavioural pharmacology.

Calcium activates and inactivates a photoreceptor soma potassium current.

D L Alkon, D. Alkon, M. Sakakibara, 1985, Biophysical journal.

Intracellular calcium signals are enhanced for days after Pavlovian conditioning.

D L Alkon, B G Schreurs, D. Alkon, 2008, Journal of neurochemistry.

CALEXCITIN-LIKE IMMIJNOREACTIVITY IN THE POND SNAIL LYMNAEA STAGNALIS

D. Alkon, M. Sakakibara, E. Ito, 2004 .

Training alone, not the tripeptide RGD, modulates calexcitin in Hermissenda.

D. Alkon, H. Epstein, A. Kuzirian, 2003, The Biological bulletin.

Calcium-regulated GTPase activity in the calcium-binding protein calexcitin.

D. Alkon, A. Quattrone, A. Pacini, 2003, Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology.

Lead, learning, and calexcitin in Hermissenda.

D. Alkon, H. Epstein, A. Kuzirian, 1998, The Biological bulletin.

Secondary Structure and Ca2+-induced Conformational Change of Calexcitin, a Learning-associated Protein*

D. Alkon, P. Gusev, C. Bertucci, 1997, The Journal of Biological Chemistry.

c‐Src protein tyrosine kinase activity is required for muscarinic receptor‐mediated DNA synthesis and neurogenesis via ERK1/2 and c‐AMP‐responsive element‐binding protein signaling in neural precursor cells

D. Alkon, Wei⁃qin Zhao, Wu Ma, 2003, Journal of neuroscience research.

Voltage noise from hair cells during mechanical stimulation

D. Alkon, L. DeFelice, 1977, Nature.

Effects of chronic bryostatin‐1 on treatment‐resistant depression in rats

D. Alkon, Miao‐kun Sun, J. Hongpaisan, 2017, European journal of pharmacology.

The Economy of Photoreceptor Function in a Primitive Nervous System

D. Alkon, 1976 .

Inositol trisphosphate regulation of photoreceptor membrane currents.

D L Alkon, D. Alkon, J. Neary, 1986, Biophysical journal.

Ultrastructure of photoreceptors in the eye ofHermissenda labelled with intracellular injections of horseradish peroxidase

D L Alkon, D. Alkon, E. Heldman, 1979, Journal of neurocytology.

Running title : Rescuing synapses and spatial memory in young fragile X mice

D. Alkon, Miao‐kun Sun, J. Hongpaisan, 2016 .

Hair Cell Interactions in the Statocyst of Hermissenda

P. Detwiler, D. Alkon, 1973, The Journal of general physiology.

Hair Cell Generator Potentials

D. Alkon, A. Bak, 1973, The Journal of general physiology.

DETWILER AND ALKON Hair Cell Interactions in Statocyst of Hermissenda 619 Recently Alkon and Bak

P. Detwiler, D. Alkon, 2003 .

Posttranscriptional regulation of gene expression in learning by the neuronal ELAV-like mRNA-stabilizing proteins

D. Alkon, P. Gusev, A. Quattrone, 2001 .

Functional Characterization of the Squid Calexcitin-2, a Calcium and GTP-binding Protein

D. Alkon, T. Nelson, S. Park, 2000 .

Multiple components of learning and memory in Aplysiu : excitatory and inhibitory information processing in a restricted neural network

B. McNaughton, M. Mishkin, D. Alkon, 2011 .

Interaction of chemosensory, visual, and statocyst pathways in Hermissenda crassicornis

D. Alkon, J. Harrigan, T. Akaike, 1978, The Journal of general physiology.

Persistent Inactivation of Potassium Currents by Elevation of Intracellular Calcium

D. Alkon, 1986 .

Neural correlates of associative training in Hermissenda

D. Alkon, 1975, The Journal of general physiology.

Neural Organization of a Molluscan Visual System

D. Alkon, Daniel L. Alkon, 1973, The Journal of general physiology.

Calcium-dependent potassium conductance in the photoresponse of a nudibranch mollusk

D. Alkon, Y. Grossman, Jeffrey A. Schmidt, 1981 .

Discrimination learning alters the distribution of protein kinase C in the hippocampus of rats

D L Alkon, M Mishkin, M. Mishkin, 1990, The Journal of neuroscience : the official journal of the Society for Neuroscience.

Stress: perspectives on its impact on cognition and pharmacological treatment

D. Alkon, Miao‐kun Sun, Miao-Kun Sun, 2014, Behavioural pharmacology.

The ε-Isozyme of Protein Kinase C (PKCε) Is Impaired in ALS Motor Cortex and Its Pulse Activation by Bryostatin-1 Produces Long Term Survival in Degenerating SOD1-G93A Motor Neuron-like Cells

D. Alkon, E. Aronica, Grazia Maugeri, 2023, International journal of molecular sciences.

Reduction of β-Amyloid Levels by Novel Protein Kinase Cϵ Activators

D. Alkon, Yuan Luo, T. Nelson, 2009, The Journal of Biological Chemistry.

Mobilization of Calcium from Intracellular Stores, Potentiation of Neurotransmitter-Induced Calcium Transients, and Capacitative Calcium Entry by 4-Aminopyridine

D. Alkon, M. Atzori, M. Grimaldi, 2001, The Journal of Neuroscience.

Open space swimming test to index antidepressant activity

D. Alkon, Miao Sun, 2003, Journal of Neuroscience Methods.

Pharmacology of protein kinase C activators: cognition-enhancing and antidementic therapeutics.

D. Alkon, Miao‐kun Sun, Miao-Kun Sun, 2010, Pharmacology & therapeutics.

A quantum basis for the relativistic doppler effect for light

D. Alkon, 2000 .

Voltage-clamp analysis of the effects of classical conditioning on the hippocampus.

D L Alkon, D. Alkon, J V Sanchez-Andres, 1991, Journal of neurophysiology.

Voltage noise power spectra reflect ciliary movement frequencies in statocyst hair cells

D. Alkon, Y. Grossman, 1982, Neuroscience Letters.

Ocular and extraocular responses of identifiable neurons in pedal ganglia of Hermissenda crassicornis.

D. Alkon, T. P. Jerussi, 1981, Journal of neurophysiology.

The release of acetylcholine from the innervated and denervated diaphragm.

D. Alkon, J. Green, D. Schmidt, 1970, Journal of Pharmacology and Experimental Therapeutics.

Background Illumination Effects upon in Vitro Conditioning in Hermissenda

D. Alkon, D. Tomsic, 2000, Neurobiology of Learning and Memory.

Optical sectioning of HRP-stained molluscan neurons

D. Alkon, T. Crow, S. Senft, 1982, Journal of Neuroscience Methods.

Protein phosphorylation/dephosphorylation and the transient, voltage-dependent potassium conductance in Hermissenda crassicornis.

D. Alkon, J. Neary, 1983, The Journal of biological chemistry.

Regenerative changes of voltage-dependent Ca2+ and K+ currents encode a learned stimulus association.

D. Alkon, 1982, Journal de physiologie.

Sensory interactions in the nudibranch mollusk Hermissenda crassicornis.

D. Alkon, 1974, Federation proceedings.

Rescue of Synaptic Phenotypes and Spatial Memory in Young Fragile X Mice

D. Alkon, J. Hongpaisan, Miao-Kun Sun, 2016, The Journal of Pharmacology and Experimental Therapeutics.

Towards universal therapeutics for memory disorders.

D. Alkon, T. Nelson, Miao-Kun Sun, 2015, Trends in pharmacological sciences.