J. Dubochet

发表

Frozen aqueous suspensions

J. Dubochet, Jiin-Ju Chang, R. Freeman, 1982 .

Electrophoretic mobility of DNA knots

J. Dubochet, A. Stasiak, V. Katritch, 1996, Nature.

A new preparation method for dark-field electron microscopy of biomacromolecules.

J. Dubochet, M. Ducommun, M. Zollinger, 1971, Journal of ultrastructure research.

Electron microscopy of frozen biological suspensions

F P Booy, J. Dubochet, J. Lepault, 1983, Journal of microscopy.

Cryo-electron microscopy of viruses

J. Dubochet, J. Lepault, A. McDowall, 1984, Nature.

Beam damage to organic material is considerably reduced in cryo-electron microscopy.

J. Dubochet, E. Knapek, J Dubochet, 1980, Journal of molecular biology.

Cryo-electron microscopy of vitrified specimens

J. Dubochet, Jiin-Ju Chang, J. Lepault, 1988, Quarterly Reviews of Biophysics.

Cryo-negative staining.

J. Dubochet, J. Harris, S. Fuller, 1998, Micron.

Cryo‐electron microscopy of vitreous sections

J. Dubochet, Jiin-Ju Chang, A. McDowall, 2004, The EMBO journal.

Cutting artefacts and cutting process in vitreous sections for cryo-electron microscopy.

J. Dubochet, D. Studer, A. Al-Amoudi, 2005, Journal of structural biology.

Multifunctional lipid/quantum dot hybrid nanocontainers for controlled targeting of live cells.

Christophe Danelon, Michael Prummer, Horst Vogel, 2006, Angewandte Chemie.

Cryo-electron microscopy of vitreous sections of native biological cells and tissues.

J. Dubochet, A. Al-Amoudi, L. Norlén, 2004, Journal of structural biology.

Electron microscopy of frozen hydrated sections of vitreous ice and vitrified biological samples

C. A. Walter, J. Dubochet, R. Freeman, 1983, Journal of microscopy.

How to "read" a vitreous section.

J. Dubochet, M. Eltsov, A. Al-Amoudi, 2007, Methods in cell biology.

Cryo‐EM—the first thirty years

J. Dubochet, J. Dubochet, 2012, Journal of microscopy.

Luminal particles within cellular microtubules

J. Dubochet, W. Baumeister, F. Frischknecht, 2006, The Journal of cell biology.

VITRIFICATION OF PURE WATER FOR ELECTRON MICROSCOPY

J. Dubochet, A. McDowall, J. Dubochet, 1981 .

Analysis of cryo-electron microscopy images does not support the existence of 30-nm chromatin fibers in mitotic chromosomes in situ

Achilleas S Frangakis, Kazuhiro Maeshima, J. Dubochet, 2008, Proceedings of the National Academy of Sciences.

Ups and downs in early electron cryo-microscopy

J. Dubochet, E. Knapek, 2018, PLoS biology.

Determination of DNA persistence length by cryo-electron microscopy. Separation of the static and dynamic contributions to the apparent persistence length of DNA.

J. Dubochet, A. Stasiak, V. Katritch, 1995, Journal of molecular biology.

The twist, writhe and overall shape of supercoiled DNA change during counterion-induced transition from a loosely to a tightly interwound superhelix. Possible implications for DNA structure in vivo.

J. Dubochet, E. Egelman, A. Stasiak, 1994, Journal of molecular biology.

Electron microscopic localization of the binding sites of Escherichia coli RNA polymerase in the early promoter region of T7 DNA.

J. Dubochet, C. Bordier, C. Bordier, 1974, European journal of biochemistry.

Electron microscopy of frozen-hydrated bacteria

K G Lickfeld, J. Dubochet, A. McDowall, 1983, Journal of bacteriology.

Comparison of different methods for thin section EM analysis of Mycobacterium smegmatis

J. Dubochet, P. Walther, C. Bleck, 2010, Journal of microscopy.

Nanostructure of the epidermal extracellular space as observed by cryo-electron microscopy of vitreous sections of human skin.

J. Dubochet, A. Al-Amoudi, L. Norlén, 2005, The Journal of investigative dermatology.

Some progress in the use of a scanning transmission electron microscope for the observation of biomacromolecules.

J. Dubochet, A. Engel, E. Kellenberger, 1976, Journal of ultrastructure research.

Carbon loss during irradiation of T4 bacteriophages and E. coli bacteria in electron microscopes.

J. Dubochet, 1975, Journal of ultrastructure research.

High resolution dark‐field electron microscopy

J. Dubochet, 1973, Journal of microscopy.

Aggregation behavior of poly(ethylene glycol-bl-propylene sulfide) di- and triblock copolymers in aqueous solution.

J. Dubochet, J. Hubbell, M. Adrian, 2009, Langmuir : the ACS journal of surfaces and colloids.

Glass-forming microemulsions: vitrification of simple liquids and electron microscope probing of droplet-packing modes

Douglas R. MacFarlane, J. Dubochet, J. Teixeira, 1984 .

Life, Liquids and Cryo-Electron Microscopy

J. Dubochet, 1987 .

Length and shape variants of the bacteriophage T4 head: mutations in the scaffolding core genes 68 and 22

J. Dubochet, E. Kellenberger, M. Adrian, 1988, Journal of virology.

Properties of ideal composite knots

Wilma K. Olson, Andrzej Stasiak, J. Dubochet, 1997, Nature.

The apical localization of transcribing RNA polymerases on supercoiled DNA prevents their rotation around the template.

J. Dubochet, A. Stasiak, M. Adrian, 1992, The EMBO journal.

DNA at the entry-exit of the nucleosome observed by cryoelectron microscopy.

J. Dubochet, J. Bednar, A. Hamiche, 1995, Journal of structural biology.

Role of LBPA and Alix in Multivesicular Liposome Formation and Endosome Organization

Stefan Matile, Jean Gruenberg, Julien Chevallier, 2004, Science.

High resolution structural analysis of Helicobacter pylori VacA toxin oligomers by cryo-negative staining electron microscopy.

J. Dubochet, T. Cover, C. El-Bez, 2005, Journal of structural biology.

Multiple oligomeric states of the Helicobacter pylori vacuolating toxin demonstrated by cryo-electron microscopy.

J. Dubochet, T. Cover, M. Adrian, 2002, Journal of molecular biology.

Cryo‐electron microscopy of vitrified chromosomes in situ.

J. Dubochet, A. McDowall, J. M. Smith, 1986, The EMBO journal.

Twisting in a crowd.

J. Dubochet, 1993, Trends in cell biology.

Expression of chirality in columnar hexagonal phases or DNA and nucleosomes

J. Dubochet, A. Leforestier, K. Richter, 2008 .

The duck-globin messenger-ribonucleoprotein complex. Resistance to high ionic strength, particle gel electrophoresis, composition and visualisation by dark-field electron microscopy.

J. Dubochet, C. Morel, E. Gander, 1973, European journal of biochemistry.

High-pressure freezing for cryoelectron microscopy.

J. Dubochet, J. Dubochet, 1995, Trends in cell biology.

Structure of globin mRNA and mRNA-protein particles. Use of dark-field electron microscopy.

J. Dubochet, B. Lebleu, C. Morel, 1973, European journal of biochemistry.

An oscillating cryo‐knife reduces cutting‐induced deformation of vitreous ultrathin sections

J. Dubochet, D. Studer, A. Al-Amoudi, 2003, Journal of microscopy.

Amorphous solid water produced by cryosectioning of crystalline ice at 113 K

J. Dubochet, D. Studer, A. Al-Amoudi, 2002, Journal of microscopy.

Amorphous solid water produced by cryosectioning of crystalline ice at 113 K.

J. Dubochet, D. Studer, A. Al-Amoudi, 2002, Journal of microscopy.

Fine Structure of the Deinococcus radiodurans Nucleoid Revealed by Cryoelectron Microscopy of Vitreous Sections

J. Dubochet, M. Eltsov, 2005, Journal of bacteriology.

Organization of double‐stranded DNA in bacteriophages: a study by cryo‐electron microscopy of vitrified samples.

J. Dubochet, J. Lepault, E. Kellenberger, 1987, The EMBO journal.

Cryoelectron microscopy of vitrified sections: a new challenge for the analysis of functional nuclear architecture

J. Dubochet, S. Fakan, C. Bouchet-Marquis, 2005, Histochemistry and Cell Biology.

Cryo‐electron microscopy of vitrified SV40 minichromosomes: the liquid drop model.

J. Dubochet, M. Adrian, P. Schultz, 1986, The EMBO journal.

Conversion of a transmembrane to a water-soluble protein complex by a single point mutation

J. Dubochet, M. Parker, C. Morton, 2002, Nature Structural Biology.

Cryo-electron microscopy of vitreous sections of biological specimens

J. Dubochet, D. Studer, A. Al-Amoudi, 2003, Microscopy and Microanalysis.

Structure of intracellular mature vaccinia virus observed by cryoelectron microscopy

J. Dubochet, M. Adrian, K. Richter, 1994, Journal of virology.

Cryo-Electron Microscopy of DNA

J. Dubochet, A. Stasiak, J. Bednar, 1994 .

Cryoelectron microscopy of DNA molecules in solution.

J. Dubochet, A. Stasiak, M. Adrian, 1992, Methods in enzymology.

Freezing: facts and hypothesis.

J. Dubochet, A. McDowall, K. Richter, 1991, Scanning microscopy. Supplement.

High-resolution Study of DNA in Vitrified Sections

J. Dubochet, K. Richter, 1990 .

Cryoultramicrotomy: Study of ice crystals and freezing damage

J. Dubochet, A. McDowall, 1984 .

ELECTRON BEAM INDUCED “VITRIFIED ICE”

J. Dubochet, R. Freeman, J. Lepault, 1983 .

Amendment to: Electron beam damage to organic specimens at liquid helium temperature

J. Dubochet, J. Lepault, E. Knapek, 1983 .

Freezing, fracturing, and etching artifacts in particulate suspensions.

J. Dubochet, J. Lepault, 1980, Journal of Ultrastructure Research.

Selective adsorption of particles to the supporting film and its consequences on particle counts in electron microscopy.

J. Dubochet, E. Kellenberger, 1972, Microscopica acta.

Electron microscope observation of a fibre structure formed by non-specific binding of cAMP receptor protein to DNA.

J. Dubochet, J. Chang, M. Takahashi, 1981, Journal of molecular biology.

Geometry and physics of knots

J. Dubochet, R. Scharein, A. Stasiak, 1996, Nature.

On the preparation of cryosections for immunocytochemistry.

J. Dubochet, A. McDowall, G. Griffiths, 1984, Journal of ultrastructure research.

Thermodynamic and Kinetic Effects in the Aggregation Behavior of a Poly(ethylene glycol-b-propylene sulfide-b-ethylene glycol) ABA Triblock Copolymer

J. Dubochet, J. Hubbell, M. Adrian, 2005 .

Electron microscopy of frozen water and aqueous solutions

J. Dubochet, J. Dubochet, R. Freeman, 1982 .

Localization of breakage points in knotted strings

Giovanni Dietler, Sandor Kasas, J. Dubochet, 2001 .

Sulphur-bearing lipids for the covalent attachment of supported lipid bilayers to gold surfaces: a detailed characterisation and analysis

J. Dubochet, W. Knoll, H. Stahlberg, 1996 .

Comparison of slam‐freezing and high‐pressure freezing effects on the DNA cholesteric liquid crystalline structure

J. Dubochet, A. Leforestier, K. Richter, 1996, Journal of microscopy.

Nucleosome arcs and helices.

J. Dubochet, M. Noll, 1978, Science.

Sedimentation and electrophoretic migration of DNA knots and catenanes.

J. Dubochet, P. Pierański, N. J. Crisona, 1998, Journal of molecular biology.

Direct Visualization of the Outer Membrane of Mycobacteria and Corynebacteria in Their Native State

Mohamed Chami, J. Dubochet, M. Chami, 2008, Journal of bacteriology.

Cryo-Transmission Electron Microscopy of Frozen-Hydrated Sections of Escherichia coli and Pseudomonas aeruginosa

J. Dubochet, A. Al-Amoudi, T. Beveridge, 2003, Journal of bacteriology.

Granular Layer in the Periplasmic Space of Gram-Positive Bacteria and Fine Structures of Enterococcus gallinarum and Streptococcus gordonii Septa Revealed by Cryo-Electron Microscopy of Vitreous Sections

J. Dubochet, B. Zuber, M. Haenni, 2006, Journal of bacteriology.

Scaling of the average crossing number in equilateral random walks, knots and proteins

J. Dubochet, A. Stasiak, Y. Diao, 2005 .

Scaling behavior of random knots

Pierre-Edouard Sottas, Akos Dobay, J. Dubochet, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Predicting Optimal Lengths of Random Knots

J. Dubochet, P. Sottas, A. Stasiak, 2000, physics/0011061.

Tightness of random knotting.

J. Dubochet, W. Olson, V. Katritch, 2000, Physical review. E, Statistical physics, plasmas, fluids, and related interdisciplinary topics.

Knotted Fishing Line, Covalent Bonds, and Breaking Points

Giovanni Dietler, Akos Dobay, J. Dubochet, 1999 .

The mammalian central nervous synaptic cleft contains a high density of periodically organized complexes.

J. Dubochet, D. Muller, I. Nikonenko, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Self-assembly of beta-amyloid 42 is retarded by small molecular ligands at the stage of structural intermediates.

J. Dubochet, M. Adrian, W. Huber, 2000, Journal of structural biology.

Spatial visualization of DNA in solution.

J. Dubochet, E. Egelman, A. Stasiak, 1991, Journal of structural biology.

Brownian dynamics simulation of DNA condensation.

J. Dubochet, P. Sottas, A. Stasiak, 1999, Biophysical journal.

Electron microscopy of the chromosomes of dinoflagellates in situ: confirmation of Bouligand's liquid crystal hypothesis

J. Dubochet, A. McDowall, A. Gautier, 1986 .

A study of the structure of the T-layer of Bacillus brevis.

P R Smith, J. Dubochet, E. Kellenberger, 1973, Journal of supramolecular structure.

Interactions between Actin and Myosin Filaments, in Skeletal Muscle Visualized in Frozen-hydrated Thin Sections

M Unser, B L Trus, A C Steven, 2022 .

Citizen biologists

J. Dubochet, 2008, EMBO reports.

Visualization of cell microtubules in their native state

Achilleas S Frangakis, Anne-Marie Glynn, Kenneth N Goldie, 2007, Biology of the cell.

Direct visualization of supercoiled DNA molecules in solution.

J. Dubochet, M. Adrian, W. Wahli, 1990, The EMBO journal.

Are the light-harvesting I complexes from Rhodospirillum rubrum arranged around the reaction centre in a square geometry?

J. Dubochet, H. Stahlberg, R. Ghosh, 1998, Journal of molecular biology.

Bending modes of DNA directly addressed by cryo-electron microscopy of DNA minicircles

Eric J. Rawdon, John H. Maddocks, Andrzej Stasiak, 2009, Nucleic acids research.

3D reconstruction and comparison of shapes of DNA minicircles observed by cryo-electron microscopy

Mathews Jacob, Michael Unser, Andrzej Stasiak, 2006, Nucleic acids research.

3 D reconstruction and comparison of shapes of DNA minicircles observed by cryo-electron microscopy

Mathews Jacob, Michael Unser, John H. Maddocks, 2006 .

Geometry and physics of catenanes applied to the study of DNA replication.

J. Dubochet, A. Stasiak, V. Katritch, 1998, Biophysical journal.

ARC-LIKE AND HELICAL ARRANGEMENTS OF NUCLEOSOME CORES

J. Dubochet, M. Noll, 1979 .

Emerging techniques: Cryo-electron microscopy of vitrified biological specimens

J. Dubochet, J. Lepault, A. McDowall, 1985 .

Chromatin conformation and salt-induced compaction: three-dimensional structural information from cryoelectron microscopy

J. Dubochet, J. Bednar, C. Woodcock, 1995, The Journal of cell biology.

Bilayers of nucleosome core particles.

J. Dubochet, A. Leforestier, F. Livolant, 2001, Biophysical journal.

DETERMINATION OF THE DNA HELICAL REPEAT AND OF THE STRUCTURE OF SUPERCOILED DNA BY CRYO-ELECTRON MICROSCOPY

J. Dubochet, A. Stasiak, V. Katritch, 1996 .

Determination of the DNA helical repeat by cryo-electron microscopy

Andrzej Stasiak, J. Dubochet, A. Bolshoy, 1994, Nature Structural Biology.

Envelope structure of Semliki Forest virus reconstructed from cryo-electron micrographs

J. Dubochet, J. Dubochet, S. Provencher, 1986, Nature.

Study of the Deinococcus radiodurans Nucleoid by Cryoelectron Microscopy of Vitreous Sections: Supplementary Comments

J. Dubochet, M. Eltsov, 2006, Journal of bacteriology.

DNA in human and stallion spermatozoa forms local hexagonal packing with twist and many defects.

J. Dubochet, A. Leforestier, N. S. Blanc, 2001, Journal of structural biology.

Compression and crevasses in vitreous sections under different cutting conditions

J. Dubochet, B. Zuber, Han Han, 2008, Journal of microscopy.

Cryo-negative staining reduces electron-beam sensitivity of vitrified biological particles.

C El-Bez, J. Dubochet, C. Alvarez-Rúa, 2002, Journal of structural biology.

The physics of rapid cooling and its implications for cryoimmobilization of cells.

J. Dubochet, Jacques Dubochet, 2007, Methods in cell biology.

Extracellular matrix binding mixed micelles for drug delivery applications.

J. Dubochet, J. Hubbell, C. Wandrey, 2009, Journal of controlled release : official journal of the Controlled Release Society.

Head structure of bacteriophages T2 and T4.

L Landmann, J. Dubochet, E. Kellenberger, 1988, Journal of ultrastructure and molecular structure research.

Reduction of beam damage by cryoprotection at 4 K

J. Dubochet, E. Knapek, I. Dietrich, 1981 .

Switch-peptides: from conformational studies to Alzheimer's disease

J. Dubochet, M. Mutter, G. Tuchscherer, 2006 .

A Reminiscence about Early Times of Vitreous Water in Electron Cryomicroscopy.

J. Dubochet, Jacques Dubochet, 2016, Biophysical journal.

X-ray diffraction and electron microscope studies on the structure of bacterial F pili.

J. Dubochet, M. Achtman, A. Engel, 1979, Journal of molecular biology.

A simple method to measure resolution on micrographs

J. Dubochet, 1976, Journal of microscopy.

On the Development of Electron Cryo-Microscopy (Nobel Lecture).

J. Dubochet, Jacques Dubochet, 2018, Angewandte Chemie.

Evaporation during preparation of unsupported thin vitrified aqueous layers for cryo-electron microscopy.

J. Dubochet, M. Adrian, M. Cyrklaff, 1990, Journal of electron microscopy technique.

Electron beam radiation damage to organic inclusions in vitreous, cubic, and hexagonal ice

J. Dubochet, M. Adrian, Y. Talmon, 1986 .

Self-assembly of single and closely spaced nucleosome core particles

M. Noll, A. Engel, S. Zimmer, 1980, Nucleic Acids Res..

Electron beam‐induced changes in vitreous sections of biological samples

J. Dubochet, D. Studer, K. Ruhl, 1998, Journal of microscopy.

Low temperature electron microscopy.

F P Booy, C. A. Walter, J. Dubochet, 1981, Annual review of biophysics and bioengineering.

The cell in absence of aggregation artifacts.

J. Dubochet, N. S. Blanc, N. Sartori Blanc, 2001, Micron.

The reaction centre of the photounit of Rhodospirillum rubrum is anchored to the light-harvesting complex with four-fold rotational disorder

J. Dubochet, H. Stahlberg, R. Ghosh, 1998, Photosynthesis Research.

Electron microscopy of frozen hydrated specimens: preparation and characteristics.

J. Dubochet, J. Lepault, 1986, Methods in enzymology.

Cryo-electron microscopy of vitrified insect flight muscle.

J. Dubochet, J. Lepault, A. McDowall, 1984, Journal of molecular biology.

New EMBO Member's Review Cryo-electron microscopy of vitreous sections

J. Dubochet, Jiin-Ju Chang, A. McDowall, 2004 .

Molecular architecture of the presynaptic compartment studied by cryo-electron tomography

J. Dubochet, V. Lučić, W. Baumeister, 2008 .

Particle‐surface interaction in thin vitrified films for cryo‐electron microscopy

J. Dubochet, M. Cyrklaff, H. Gross, 1994 .

Freezing, sectioning and observation artefacts of frozen hydrated sections for electron microscopy

C. A. Walter, J. Dubochet, R. Freeman, 1983 .

Opposite effect of counterions on the persistence length of nicked and non-nicked DNA.

J. Dubochet, V. Katritch, J. Bednar, 1997, Journal of molecular biology.

Crystalline aggregation of a proteolytic fragment of the major head protein of bacteriophage T4.

J. Dubochet, A. Tsugita, U. Aebi, 1979, Journal of molecular biology.

Improved anticontaminator for cryo‐electron microscopy with a Philips EM 400

J. Dubochet, J. Lepault, J. Homo, 1984 .

Reduction of Radiation Damage by Imaging with a Superconducting Lens System

J. Dubochet, E. Knapek, R. Weyl, 1980 .

Extracellular matrix binding mixed micelles for drug delivery applications.

J. Dubochet, J. Hubbell, C. Wandrey, 2009, Journal of controlled release : official journal of the Controlled Release Society.

A model for cryosectioning based on the morphology of vitrified ultrathin sections

J. Dubochet, K. Richter, J Dubochet, 1991, Journal of microscopy.

Genomics for citizens

J. Dubochet, 2009, EMBO reports.