E. Unanue

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Interleukin 1 is Potent Modulator of Insulin Secretion from Isolated Rat Islets of Langerhans

P. Comens, B. Wolf, E. Unanue, 1987, Diabetes.

Amino-terminal trimming of peptides for presentation on major histocompatibility complex class II molecules.

E. Unanue, C. Nelson, I. Vidavsky, 1997, Proceedings of the National Academy of Sciences of the United States of America.

T helper cell subsets require the expression of distinct costimulatory signals by antigen-presenting cells.

E. Unanue, C. Weaver, C. Hawrylowicz, 1988, Proceedings of the National Academy of Sciences of the United States of America.

The level of peptide‐MHC complex determines the susceptibility to autoimmune diabetes: studies in HEL transgenic mice

E. Unanue, R. DiPaolo, 2001, European journal of immunology.

Embryonic and adult-derived resident cardiac macrophages are maintained through distinct mechanisms at steady state and during inflammation.

Ansuman T. Satpathy, E. Unanue, D. Mann, 2014, Immunity.

Crystal structure of I-Ak in complex with a dominant epitope of lysozyme.

W A Hendrickson, E. Unanue, C. Nelson, 1998, Immunity.

Structural basis of peptide binding and presentation by the type I diabetes-associated MHC class II molecule of NOD mice.

E. Unanue, C. Nelson, D. Fremont, 2000, Immunity.

In APCs, the Autologous Peptides Selected by the Diabetogenic I-Ag7 Molecule Are Unique and Determined by the Amino Acid Changes in the P9 Pocket1

Emil R. Unanue, Osami Kanagawa, Michael L. Gross, 2002, The Journal of Immunology.

Natural peptides selected by diabetogenic DQ8 and murine I-A(g7) molecules show common sequence specificity.

James J Walters, Michael L Gross, Emil R Unanue, 2005, The Journal of clinical investigation.

Recombinant Listeria monocytogenes Expressing a Cell Wall-Associated Listeriolysin O Is Weakly Virulent but Immunogenic

E. Unanue, H. Vivanco-Cid, Javier A. Carrero, 2009, Infection and Immunity.

Presentation of Listeria monocytogenes to CD8+ T cells requires secretion of hemolysin and intracellular bacterial growth.

E. Unanue, D. Portnoy, L. Brunt, 1990, Journal of immunology.

Studies in listeriosis show the strong symbiosis between the innate cellular system and the T‐cell response

E. Unanue, 1997, Immunological reviews.

Quantitation of antigen-presenting cell MHC class II/peptide complexes necessary for T-cell stimulation

Emil R. Unanue, Clifford V. Harding, E. Unanue, 1990, Nature.

Class-switched anti-insulin antibodies originate from unconventional antigen presentation in multiple lymphoid sites

E. Unanue, James W. Thomas, Xiaoxiao Wan, 2016, The Journal of experimental medicine.

Why Listeriosis? A perspective on cellular immunity to infection

E. Unanue, 1997, Immunological reviews.

Macrophage-T cell interactions involving Listeria monocytogenes--role of the H-2 gene complex.

E. Unanue, J. Kíely, A. Farr, 1979, Journal of immunology.

Studies with Listeria monocytogenes lead the way.

E. Unanue, Javier A. Carrero, 2012, Advances in immunology.

REQUIREMENT OF THYMUS (T) LYMPHOCYTES FOR RESISTANCE TO LISTERIOSIS

E. Unanue, F. Lane, Emil R. Unanue, 1972, The Journal of experimental medicine.

Secretion of mediators following T lymphocyte-macrophage interaction is regulated by the major histocompatibility complex.

E. Unanue, M. Dorf, A. Farr, 1977, Proceedings of the National Academy of Sciences of the United States of America.

In Autoimmune Diabetes Unique Autoreactive T Cells Recognize Insulin Peptides Generated in the Islets of Langerhans

E. Unanue, B. Calderon, S. Petzold, 2010, Nature Immunology.

A mononuclear cell component in experimental immunological glomerulonephritis

E. Unanue, R. Cotran, V. Pardo, 1978, The Journal of experimental medicine.

The binding of clathrin triskelions to membranes from coated vesicles

E. Unanue, D. Branton, E. Ungewickell, 1981, Cell.

Position β57 of I-Ag7 controls early anti-insulin responses in NOD mice, linking an MHC susceptibility allele to type 1 diabetes onset

E. Unanue, A. Su, C. Mathews, 2019, Science Immunology.

Antigen presentation in the autoimmune diabetes of the NOD mouse.

E. Unanue, 2014, Annual review of immunology.

Unconventional recognition of peptides by T cells and the implications for autoimmunity

E. Unanue, James F. Mohan, 2012, Nature Reviews Immunology.

E. Unanue, S. Petzold, James F. Mohan, 2011, The Journal of experimental medicine.

T cells distinguish MHC-peptide complexes formed in separate vesicles and edited by H2-DM.

E. Unanue, Scott B. Lovitch, E. Bikoff, 2004, Immunity.

Hindering auxiliary anchors are potent modulators of peptide binding and selection by I-Ak class II molecules.

E. Unanue, R. Latek, S. Petzold, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Ligand-induced association of surface immunoglobulin with the detergent-insoluble cytoskeletal matrix of the B lymphocyte.

E. Unanue, P. Hochman, J. Braun, 1982, Journal of immunology.

Expression of membrane interleukin 1 by fibroblasts transfected with murine pro-interleukin 1 alpha cDNA.

E. Unanue, D. Chaplin, R. Fuhlbrigge, 1988, Proceedings of the National Academy of Sciences of the United States of America.

Corticosteroids inhibit murine macrophage Ia expression and interleukin 1 production.

E. Unanue, D. S. Snyder, D. Snyder, 1982, Journal of immunology.

THE MODULATION OF IMMUNOGLOBULIN IN B LYMPHOCYTES AND ITS RELEVANCE TO IMMUNE STIMULATION

E. Unanue, G. Schreiner, 1975 .

TCR-mediated adhesion of T cell hybridomas to planar bilayers containing purified MHC class II/peptide complexes and receptor shedding during detachment.

E. Unanue, C. Nelson, N. Viner, 1996, Journal of immunology.

Cutting Edge: Chemical Dominance Does Not Relate to Immunodominance: Studies of the CD4+ T Cell Response to a Model Antigen

E. Unanue, R. DiPaolo, 2002, The Journal of Immunology.

Immunity to Listeria infection.

E. Unanue, B. Edelson, 2000, Current opinion in immunology.

Identification of a major I-Ek-restricted determinant of hen egg lysozyme: limitations of lymph node proliferation studies in defining immunodominance and crypticity.

E. Unanue, C. Nelson, N. Viner, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Stimulation of nonlymphoid mesenchymal cell proliferation by a macrophage-derived growth factor.

E. Unanue, R. Cotran, B. Martin, 1981, Journal of immunology.

A ROLE OF POLYMORPHONUCLEAR LEUKOCYTES AND COMPLEMENT IN NEPHROTOXIC NEPHRITIS

E. Unanue, C. Cochrane, F. Dixon, 1965, The Journal of experimental medicine.

Interleukin-1 is linked to the respiratory epithelial cytopathology of pertussis

E. Unanue, W. Goldman, S. Moser, 1993, Infection and immunity.

Cutting Edge: H-2DM Is Responsible for the Large Differences in Presentation Among Peptides Selected by I-Ak During Antigen Processing 1

E. Unanue, Scott B. Lovitch, S. Petzold, 2003, The Journal of Immunology.

Decrease in macrophage antigen catabolism caused by ammonia and chloroquine is associated with inhibition of antigen presentation to T cells.

E. Unanue, H. Ziegler, Emil R. UNANUEt, 1982, Proceedings of the National Academy of Sciences of the United States of America.

Lymphocyte apoptosis as an immune subversion strategy of microbial pathogens.

E. Unanue, Javier A. Carrero, 2006, Trends in immunology.

MyD88-Dependent but Toll-Like Receptor 2-Independent Innate Immunity to Listeria: No Role for Either in Macrophage Listericidal Activity1

E. Unanue, B. Edelson, 2002, The Journal of Immunology.

Binding of photoreactive lysozyme peptides to murine histocompatibility class II molecules.

E. Unanue, P. Allen, I. Luescher, 1988, Proceedings of the National Academy of Sciences of the United States of America.

Analysis of the interaction of peptide hen egg white lysozyme (34-45) with the I-Ak molecule.

E. Unanue, L. Lambert, 1989, Journal of immunology.

Liposome-encapsulated antigens are processed in lysosomes, recycled, and presented to T cells

E. Unanue, J. Slot, H. Geuze, 1991, Cell.

LIGAND-INDUCED MOVEMENT OF LYMPHOCYTE MEMBRANE MACROMOLECULES

E. Unanue, M. Karnovsky, W. Perkins, 1972, The Journal of experimental medicine.

Calcium-sensitive modulation of Ig capping: evidence supporting a cytoplasmic control of ligand-receptor complexes

E. Unanue, G. Schreiner, 1976, The Journal of experimental medicine.

Redistribution of myosin accompanying capping of surface Ig

E. Unanue, T. Pollard, K. Fujiwara, 1977, The Journal of experimental medicine.

Two distinct mechanisms for redistribution of lymphocyte surface macromolecules. II. Contrasting effects of local anesthetics and a calcium ionophore

E. Unanue, T. Pollard, K. Fujiwara, 1978, The Journal of cell biology.

Two distinct mechanisms for redistribution of lymphocyte surface macromolecules. I. Relationship to cytoplasmic myosin

E. Unanue, T. Pollard, K. Fujiwara, 1978, The Journal of cell biology.

The basis for the immunoregulatory role of macrophages and other accessory cells.

E. Unanue, P. Allen, 1987, Science.

The regulatory role of macrophages in antigenic stimulation. Part Two: symbiotic relationship between lymphocytes and macrophages.

E. Unanue, 1981, Advances in immunology.

Binding of poly (Glu-60 Ala-30 Tyr-10) by thymic lymphocytes from genetic responder and non-responder mice: effect of antihistocompatibility serum.

E. Unanue, B. Benacerraf, M. Dorf, 1975, Journal of immunology.

Chronic Listeria infection in SCID mice: requirements for the carrier state and the dual role of T cells in transferring protection or suppression.

E. Unanue, P. Swanson, O. Kanagawa, 1998, Journal of immunology.

Liposome-encapsulated antigens engender lysosomal processing for class II MHC presentation and cytosolic processing for class I presentation.

E. Unanue, C. Harding, O. Kanagawa, 1991, Journal of immunology.

The immune response of mice to antigen in macrophages.

E. Unanue, B. Askonas, 1968, Immunology.

Presentation on class II MHC molecules of endogenous lysozyme targeted to the endocytic pathway.

E. Unanue, I. Vidavsky, M. Gross, 1997, Journal of immunology.

Cutting edge: negative selection of immature thymocytes by a few peptide-MHC complexes: differential sensitivity of immature and mature T cells.

E. Unanue, D. Peterson, R. DiPaolo, 1999, Journal of immunology.

The cellular niche of Listeria monocytogenes infection changes rapidly in the spleen

Mark J. Miller, E. Unanue, M. Miller, 2009, European journal of immunology.

Secretory function of mononuclear phagocytes: a review.

E. Unanue, 1976, The American journal of pathology.

The Insulin-Specific T Cells of Nonobese Diabetic Mice Recognize a Weak MHC-Binding Segment in More Than One Form1

E. Unanue, A. Suri, S. Petzold, 2007, The Journal of Immunology.

Regulation of macrophage populations. I. Preferential induction of Ia-rich peritoneal exudates by immunologic stimuli.

E. Unanue, J. Kíely, D. Beller, 1980, Journal of immunology.

IMMUNOGLOBULINS ON THE SURFACE OF LYMPHOCYTES

E. Unanue, H. Grey, S. Colon, 1971, The Journal of experimental medicine.

Identifying the Initiating Events of Anti-Listeria Responses Using Mice with Conditional Loss of IFN-γ Receptor Subunit 1 (IFNGR1)

E. Unanue, R. Schreiber, J. White, 2013, The Journal of Immunology.

The Secrets of the Class II MHC Peptidome Start To Be Revealed

E. Unanue, 2016, The Journal of Immunology.

Antigen Presentation Via MHC Class II Molecules

E. Unanue, 1998 .

The role of I-Ag7 beta chain in peptide binding and antigen recognition by T cells.

E. Unanue, J. Shimizu, O. Kanagawa, 1997, International immunology.

Appreciating the Complexity of MHC Class II Peptide Binding: Lysozyme Peptide and I‐Ak

E. Unanue, C. Nelson, N. Viner, 1996, Immunological reviews.

Cutting Edge: The Relative Distribution of T Cells Responding to Chemically Dominant or Minor Epitopes of Lysozyme Is Not Affected by CD40-CD40 Ligand and B7-CD28-CTLA-4 Costimulatory Pathways1

E. Unanue, R. DiPaolo, 2002, The Journal of Immunology.

Turnover of Ia-peptide complexes is facilitated in viable antigen-presenting cells: biosynthetic turnover of Ia vs. peptide exchange.

E. Unanue, C. Harding, R. W. Roof, 1989, Proceedings of the National Academy of Sciences of the United States of America.

Reduction of disulfide bonds within lysosomes is a key step in antigen processing.

E. Unanue, C. Harding, D. Collins, 1991, Journal of immunology.

Distinct antigen MHC class II complexes generated by separate processing pathways.

E. Unanue, R. Lindner, Emil R. Unanue, 1996, The EMBO journal.

Chemotaxis of rat lymphocytes.

E. Unanue, P. Ward, G. Schreiner, 1977, Journal of immunology.

The fate of anti-Ig-surface Ig complexes on B lymphocytes.

E. Unanue, H. Engers, Emil R. Unanue, 1973, Journal of immunology.

Endocytosis by lymphocytes of complexes of anti-Ig with membrane-bound Ig.

E. Unanue, M. Karnovsky, W. Perkins, 1972, Journal of immunology.

This information is current as Immature and Mature T Cells Complexes: Differential Sensitivity of Thymocytes by a Few Peptide-MHC Cutting Edge: Negative Selection of Immature

E. Unanue, D. Peterson, R. DiPaolo, 2013 .

Dendritic cells in islets of Langerhans constitutively present β cell-derived peptides bound to their class II MHC molecules

Mark J. Miller, E. Unanue, M. Miller, 2008, Proceedings of the National Academy of Sciences.

Phospholipids enhance the binding of peptides to class II major histocompatibility molecules.

E. Unanue, I. Luescher, R. W. Roof, 1990, Proceedings of the National Academy of Sciences of the United States of America.

Antigen processing and intracellular Ia. Possible roles of endocytosis and protein synthesis in Ia function.

E. Unanue, C. Harding, 1989, Journal of immunology.

Influence of saccharide size on the cellular immune response to glycopeptides.

E. Unanue, J. Kihlberg, P. Sjölin, 2003, Organic & biomolecular chemistry.

MHC-restricted, glycopeptide-specific T cells show specificity for both carbohydrate and peptide residues.

E. Unanue, J. Kihlberg, P. Sjölin, 1999, Journal of immunology.

Specificity of glycopeptide-specific T cells.

E. Unanue, J. Kihlberg, M. Elofsson, 1995, Journal of immunology.

common sequence specificity

E. Unanue, M. Gross, A. Suri, 2013 .

Cutting Edge: Unique T Cells That Recognize Citrullinated Peptides Are a Feature of Protein Immunization1

E. Unanue, Jeremy W. Herzog, Jamie M. Ireland, 2006, The Journal of Immunology.

Protein Immunization Citrullinated Peptides Are a Feature of Cutting Edge: Unique T Cells That Recognize

E. Unanue, Jeremy W. Herzog, Jamie M. Ireland, 2006 .

Activated antigen-presenting cells select and present chemically modified peptides recognized by unique CD4 T cells

E. Unanue, Y. Maekawa, Jeremy W. Herzog, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Conformational isomers of a peptide–class II major histocompatibility complex

E. Unanue, Scott B. Lovitch, 2005, Immunological reviews.

in the P9 Pocket and Determined by the Amino Acid Changes Molecule Are Unique g7 the Diabetogenic I-A In APCs, the Autologous Peptides Selected by

E. Unanue, I. Vidavsky, O. Kanagawa, 2002 .

Deamidation of Asparagine in a Major Histocompatibility Complex–Bound Peptide Affects T Cell Recognition but Does Not Explain Type B Reactivity

E. Unanue, Z. Pu, T. P. Cirrito, 2001, The Journal of experimental medicine.

Cells Show Specificity for Both Carbohydrate MHC-Restricted, Glycopeptide-Specific T

E. Unanue, P. Sjölin, M. Deck, 1999 .

Two Structural States of Complexes of Peptide and Class II Major Histocompatibility Complex Revealed by Photoaffinity-labeled Peptides*

E. Unanue, S. Petzold, E. Carrasco-Marín, 1999, The Journal of Biological Chemistry.

Effects of pH and polysaccharides on peptide binding to class II major histocompatibility complex molecules.

E. Unanue, P. Allen, C. Harding, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Insights into the chemistry and biology of the I-Ag7 class II molecule.

E. Unanue, O. Kanagawa, E. Carrasco-Marín, 1997, Research in immunology.

The sites in the I-Ak histocompatibility molecule photoaffinity labeled by an immunogenic lysozyme peptide.

E. Unanue, B. Schwartz, D. Crimmins, 1990, The Journal of biological chemistry.

The MHC-II peptidome of pancreatic islets identifies key features of autoimmune peptides

Cheryl F. Lichti, E. Unanue, A. Chervonsky, 2020, Nature Immunology.

Textbook of immunology

E. Unanue, B. Benacerraf, 1979 .

Experimental glomerulonephritis: immunological events and pathogenetic mechanisms.

E. Unanue, F. Dixon, Frank J. Dixon, 1967, Advances in immunology.

Origin of the rat mesangial phagocyte and its expression of the leukocyte common antigen.

E. Unanue, G. Schreiner, 1984, Laboratory investigation; a journal of technical methods and pathology.

Modulation of Ia and leukocyte common antigen expression in rat glomeruli during the course of glomerulonephritis and aminonucleoside nephrosis.

E. Unanue, R. Cotran, G. Schreiner, 1984, Laboratory investigation; a journal of technical methods and pathology.

Characterization of resident glomerular cells in the rat expressing Ia determinants and manifesting genetically restricted interactions with lymphocytes.

E. Unanue, R. Cotran, J. Kíely, 1981, The Journal of clinical investigation.

Glycopeptides bind MHC molecules and elicit specific T cell responses.

E. Unanue, J. Kihlberg, C. Harding, 1993, Journal of immunology.

Ito cells, stellate cells, and myofibroblasts: new actors in antigen presentation.

E. Unanue, 2007, Immunity.

Interferon-Mediated Induction of la Antigen Expression on Isolated Murine Whole Islets and Dispersed Islet Cells

E. Unanue, P. Lacy, J. Wright, 1986, Diabetes.

In CD4+ T-cell-induced diabetes, macrophages are the final effector cells that mediate islet beta-cell killing: studies from an acute model.

E. Unanue, B. Calderon, A. Suri, 2006, The American journal of pathology.

α-fetoprotein inhibits macrophage expression of Ia antigens

E. Unanue, Christopher Y. Lu, P. Changelian, 1984 .

Prostaglandins modulate macrophage Ia expression

E. Unanue, D. Beller, D. S. Snyder, 1982, Nature.

Regulation of autoimmune diabetes by non‐islet‐specific T cells — a role for the glucocorticoid‐induced TNF receptor

E. Unanue, J. Katz, J. Shimizu, 2004, European journal of immunology.

Control of B-lymphocyte function. I. Inactivation of mitogenesis by interactions with surface immunoglobulin and Fc-receptor molecules

E. Unanue, C. Sidman, 1976, The Journal of experimental medicine.

Intracellular pathogens and antigen presentation-new challenges with Legionella pneumophila.

E. Unanue, 2003, Immunity.

Antigen presentation.

E. Unanue, J. Cerottini, 1989, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Processing of lysozyme by macrophages: identification of the determinant recognized by two T-cell hybridomas.

E. Unanue, P. Allen, D. J. Strydom, 1984, Proceedings of the National Academy of Sciences of the United States of America.

Nitric oxide production in islets from nonobese diabetic mice: aminoguanidine-sensitive and -resistant stages in the immunological diabetic process.

E. Unanue, M. Mcdaniel, J. Corbett, 1993, Proceedings of the National Academy of Sciences of the United States of America.

The pancreas anatomy conditions the origin and properties of resident macrophages

E. Unanue, K. Murphy, G. Randolph, 2015, The Journal of experimental medicine.

Macrophages and dendritic cells in islets of Langerhans in diabetic autoimmunity: a lesson on cell interactions in a mini-organ.

E. Unanue, Javier A. Carrero, Stephen T. Ferris, 2016, Current opinion in immunology.

Regulation of macrophage Ia expression in mice with severe combined immunodeficiency: induction of Ia expression by a T cell-independent mechanism.

E. Unanue, G. Bancroft, G. Bosma, 1986, Journal of immunology.

Stimulation of Vascular Cell Growth by Macrophage Products

E. Unanue, R. Cotran, M. Gimbrone, 1982 .

Autoantibodies and CD4 T cells target a beta cell retroviral envelope protein in non-obese diabetic mice.

E. Unanue, I. Vidavsky, M. Gross, 2003, International immunology.

Despite ubiquitous autoantigen expression, arthritogenic autoantibody response initiates in the local lymph node

E. Unanue, P. Allen, L. Mandik-Nayak, 2002, Proceedings of the National Academy of Sciences of the United States of America.

A T cell-independent mechanism of macrophage activation by interferon-gamma.

E. Unanue, R. Schreiber, G. Bancroft, 1987, Journal of immunology.

Entry of diabetogenic T cells into islets induces changes that lead to amplification of the cellular response

Mark J. Miller, E. Unanue, M. Miller, 2011, Proceedings of the National Academy of Sciences.

Cellular and molecular events in the localization of diabetogenic T cells to islets of Langerhans

Mark J. Miller, E. Unanue, M. Miller, 2011, Proceedings of the National Academy of Sciences.

Regulation of gamma interferon production by natural killer cells in scid mice: roles of tumor necrosis factor and bacterial stimuli

E. Unanue, R. Schreiber, J. Wherry, 1991, Infection and immunity.

Cooperation between mononuclear phagocytes and lymphocytes in immunity.

E. Unanue, 1980, The New England journal of medicine.

CRITICAL ROLE OF DETERMINANT PRESENTATION IN THE INDUCTION OF SPECIFIC RESPONSES IN IMMUNO-COMPETENT LYMPHOCYTES

E. Unanue, D. Katz, D. H. Katz, 1973, The Journal of experimental medicine.

MHC-II neoantigens shape tumor immunity and response to immunotherapy

Maxim N. Artyomov, Cheryl F. Lichti, E. Unanue, 2019, Nature.

IFN-γ-Dependent Regulatory Circuits in Immune Inflammation Highlighted in Diabetes1

E. Unanue, J. Mills, B. Calderon, 2008, The Journal of Immunology.

Immunological Reversal of Autoimmune Diabetes Without Hematopoietic Replacement of ß Cells

E. Unanue, T. Esparza, B. Calderon, 2006, Science.

Immune complexes inhibit antimicrobial responses through interleukin-10 production. Effects in severe combined immunodeficient mice during Listeria infection.

E. Unanue, C. Tripp, K. Beckerman, 1995, The Journal of clinical investigation.

A T-cell dormant state in the autoimmune process of nonobese diabetic mice treated with complete Freund's adjuvant.

E. Unanue, P. Lacy, D. Kipnis, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Activated platelets express IL-1 activity.

E. Unanue, S. Santoro, C. Hawrylowicz, 1989, Journal of immunology.

T cell-independent macrophage activation in scid mice.

E. Unanue, R. Schreiber, G. Bancroft, 1989, Current topics in microbiology and immunology.

Two loci affecting B cell responses to B cell maturation factors

J. D. Marshall, E. Unanue, J. Nadeau, 1986, The Journal of experimental medicine.

The mouse mutant "motheaten." II. Functional studies of the immune system.

E. Unanue, L. Shultz, C. Sidman, 1978, Journal of immunology.

The mouse mutant "motheaten". I. Development of lymphocyte populations.

E. Unanue, L. Shultz, C. Sidman, 1978, Journal of immunology.

A minor subset of Batf3-dependent antigen-presenting cells in islets of Langerhans is essential for the development of autoimmune diabetes.

E. Unanue, K. Murphy, Javier A. Carrero, 2014, Immunity.

Including B Cells Concentrated in a Limited Number of APCs Following Immunization Antigen Becomes

E. Unanue, R. DiPaolo, S. Petzold, 2004 .

Listeriolysin O Is Strongly Immunogenic Independently of Its Cytotoxic Activity

E. Unanue, H. Vivanco-Cid, Javier A. Carrero, 2012, PloS one.

Listeria monocytogenes induces apoptosis of infected hepatocytes.

E. Unanue, M. Callery, B. Deck, 1996, Journal of immunology.

Stimulation of human monocyte/macrophage-derived growth factor (MDGF) production by plasma fibronectin.

E. Unanue, R. Cotran, B. Martin, 1983, The American journal of pathology.

The handling of Listeria monocytogenes by macrophages: the search for an immunogenic molecule in antigen presentation.

E. Unanue, P. Allen, J. Braun, 1984, Journal of immunology.

Specificity of the T cell receptor: two different determinants are generated by the same peptide and the I-Ak molecule.

E. Unanue, E. Haber, P. Allen, 1985, Journal of immunology.

Purification and photoaffinity labeling of the I-Ak histocompatibility molecule.

E. Unanue, I. Luescher, Emil R. Unanue, 1990, Journal of immunological methods.

Ita Askonas and her influence in the field of antigen presentation.

E. Unanue, A. McMichael, 2014, Current opinion in immunology.

From antigen processing to peptide-MHC binding

E. Unanue, 2006, Nature Immunology.

Antigen presentation: comments on its regulation and mechanism.

E. Unanue, P. Allen, Christopher Y. Lu, 1984, Journal of immunology.

Regulation of macrophage populations. II. Synthesis and expression of Ia antigens by peritoneal exudate macrophages is a transient event.

E. Unanue, D. Beller, 1981, Journal of immunology.

During ontogeny, Ia-bearing accessory cells are found early in the thymus but late in the spleen.

E. Unanue, D. Beller, C. Lu, 1980, Proceedings of the National Academy of Sciences of the United States of America.

A defect in the antigen-presenting function of macrophages from neonatal mice

E. Unanue, Christopher Y. Lu, E. G. Calamai, 1979, Nature.

Indomethacin in vivo increases the sensitivity to Listeria infection in mice. A possible role for macrophage thromboxane A2 synthesis.

E. Unanue, P. Needleman, C. Tripp, 1987, The Journal of clinical investigation.

Monocyte migration explains the changes in macrophage arachidonate metabolism during the immune response.

E. Unanue, P. Needleman, C. Tripp, 1986, Proceedings of the National Academy of Sciences of the United States of America.

Identification of a macrophage antigen-processing event required for I-region-restricted antigen presentation to T lymphocytes.

E. Unanue, K. Ziegler, 1981, Journal of immunology.

b cell apoptosis in T cell-mediated autoimmune diabetes

E. Unanue, 1997 .

Neutrophils control the magnitude and spread of the immune response in a thromboxane A2-mediated process

E. Unanue, Chiao-Wen Yang, 2013, The Journal of experimental medicine.

Dressing for the occasion: APCs make antigens presentable.

E. Unanue, J. McCluskey, 2008, Current opinion in immunology.

Activation of Type B T Cells after Protein Immunization Reveals Novel Pathways of In Vivo Presentation of Peptides1

E. Unanue, T. Esparza, Scott B. Lovitch, 2007, The Journal of Immunology.

Vivo Presentation of Peptides Immunization Reveals Novel Pathways of In Activation of Type B T Cells after Protein

E. Unanue, T. Esparza, Scott B. Lovitch, 2006 .

Non-Random Distribution of Surface Immunoglobulin on Murine B Lymphocytes

E. Unanue, A. Abbas, M. Karnovsky, 1975, The Journal of Immunology.

Immunogenicity of macrophage‐bound antigens: the requirement for hapten and carrier determinants to be on the same molecule for t and b lymphocyte collaboration

E. Unanue, D. Katz, M. Lewis, 1973, European journal of immunology.

Failure of lymphocytes to reexpress antigen receptors after brief interaction with a tolerogenic D-amino acid copolymer.

E. Unanue, D. Katz, B. Benacerraf, 1974, Proceedings of the National Academy of Sciences of the United States of America.

PERSISTENCE OF IMMUNOGENICITY OF ANTIGEN AFTER UPTAKE BY MACROPHAGES

E. Unanue, B. Askonas, 1968, The Journal of experimental medicine.

ZnT8-Reactive T Cells Are Weakly Pathogenic in NOD Mice but Can Participate in Diabetes Under Inflammatory Conditions

E. Unanue, D. Nayak, B. Calderon, 2014, Diabetes.

Macrophages and cellular immunity in experimental glomerulonephritis

E. Unanue, R. Cotran, G. Schreiner, 2005, Springer Seminars in Immunopathology.

Regulation of immunity and inflammation by mediators from macrophages.

E. Unanue, J. Kíely, M. Stadecker, 1976, The American journal of pathology.

A Role of Mononuclear Phagocytes in Immunologically Induced Glomerulonephritis

E. Unanue, R. Cotran, G. Schreiner, 1983 .

The costimulatory function of antigen-presenting cells.

E. Unanue, C. Weaver, 1990, Immunology today.

Regulation of interleukin 1 gene expression by adherence and lipopolysaccharide.

E. Unanue, D. Chaplin, J. Kíely, 1987, Journal of immunology.

Isolation of phagocytic cells from the rat renal glomerulus.

E. Unanue, S. Camazine, M. Karnovsky, 1976, Laboratory investigation; a journal of technical methods and pathology.

Properties and Some Uses of Anti-macrophage Antibodies

E. Unanue, 1968, Nature.

Demonstration of a soluble mediator that induces exudates rich in Ia- positive macrophages

E. Unanue, D. Beller, M. Scher, 1980, The Journal of experimental medicine.

EXPERIMENTAL GLOMERULONEPHRITIS

E. Unanue, F. Dixon, 1964, The Journal of experimental medicine.

Antigen presentation 1

E. Unanue, J. Cerottini, J. Cerottini, 1989, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Further Analysis of the Role of MHC Molecules in Antigen Presentation

E. Unanue, C. Harding, I. Luescher, 1989 .

Mechanisms of Antigen Processing

E. Unanue, C. Harding, F. Leyva-Cobián, 1988, Immunological reviews.

Intracellular interference with antigen presentation.

E. Unanue, F. Leyva-Cobián, 1988, Journal of immunology.

Early, transient depletion of plasmacytoid dendritic cells ameliorates autoimmunity in a lupus model

E. Unanue, M. Colonna, S. Rowland, 2014, The Journal of experimental medicine.

Release of IL-1 from mononuclear phagocytes.

E. Unanue, K. Hogquist, D. Chaplin, 1991, Journal of immunology.

Across A Range of Maturation States Dendritic Cells Process and Present Antigens

E. Unanue, M. Colonna, M. Cella, 2003 .

Autophagy in antigen-presenting cells results in presentation of citrullinated peptides to CD4 T cells

E. Unanue, Jamie M. Ireland, 2011, The Journal of experimental medicine.

Interferon-producing Cells Fail to Induce Proliferation of Naive T Cells but Can Promote Expansion and T Helper 1 Differentiation of Antigen-experienced Unpolarized T Cells

E. Unanue, M. Colonna, M. Cella, 2003, The Journal of experimental medicine.

Macrophage activation by IgE.

E. Unanue, A. Capron, M. Joseph, 1980 .

Neutrophils are involved in acute, nonspecific resistance to Listeria monocytogenes in mice

E. Unanue, H. Rogers, H. W. Rogers, 1993, Infection and immunity.

Neutrophils Influence the Level of Antigen Presentation during the Immune Response to Protein Antigens in Adjuvants

Mark J. Miller, E. Unanue, M. Miller, 2010, The Journal of Immunology.

in AdjuvantsResponse to Protein Antigens Antigen Presentation during the Neutrophils Influence the Level of

Mark J. Miller, E. Unanue, M. Miller, 2010 .

Protein Antigens in Adjuvants Presentation during the Immune Response to Neutrophils Influence the Level of Antigen

Mark J. Miller, E. Unanue, M. Miller, 2010 .

Low‐temperature inhibition of antigen processing and iron uptake from transferrin: Deficits in endosome functions at 18 °C

E. Unanue, C. Harding, Clifford V. Harding, 1990 .

T cell induction of membrane IL 1 on macrophages.

E. Unanue, C. Weaver, 1986, Journal of immunology.

The functional significance of the regulation of macrophage Ia expression by endogenous arachidonate metabolites in vitro.

E. Unanue, P. Needleman, C. Tripp, 1986, Journal of immunology.

In vivo and in vitro expression of macrophage membrane interleukin 1 in response to soluble and particulate stimuli.

E. Unanue, H. Virgin, E. Kurt-Jones, 1986, Journal of immunology.

Comment on the finding of Ia expression in nonlymphoid cells.

E. Unanue, P. Allen, 1986, Laboratory investigation; a journal of technical methods and pathology.

Relationship of macrophage Ia and membrane IL 1 expression to antigen presentation.

E. Unanue, H. Virgin, E. Kurt-Jones, 1985, Journal of immunology.

Conditions required for expression of membrane IL 1 on B cells.

E. Unanue, J. Kíely, E. Kurt-Jones, 1985, Journal of immunology.

Ia-bearing macrophages in athymic mice: antigen presentation and regulation.

E. Unanue, C. Lu, E. Peters, 1981, Journal of immunology.

Antigen-presenting function of alveolar macrophages: uptake and presentation of Listeria monocytogenes.

E. Unanue, D. Weinberg, 1981, Journal of immunology.

Nonspecific "lymphocyte activating" factors produced by macrophages.

E. Unanue, D. Rosenstreich, T. Diamantstein, 1979, Cellular immunology.

The modulation of lymphocyte functions by molecules secreted by macrophages. I. Description and partial biochemical analysis

E. Unanue, J. Kíely, J. L. Lefko, 1975, The Journal of experimental medicine.

Pathogenic CD4+ T cells recognizing an unstable peptide of insulin are directly recruited into islets bypassing local lymph nodes

Mark S. Anderson, E. Unanue, B. Calderon, 2013, The Journal of experimental medicine.

Weak Proinsulin Peptide–Major Histocompatibility Complexes Are Targeted in Autoimmune Diabetes in Mice

E. Unanue, A. Suri, M. Levisetti, 2008, Diabetes.

Weak proinsulin peptide-MHC complexes are targeted in autoimmune diabetes in mice

E. Unanue, A. Suri, M. Levisetti, 2008 .

Diabetes Is Predicted by the β Cell Level of Autoantigen1

E. Unanue, G. Schweitzer, C. Byersdorfer, 2005, The Journal of Immunology.

MACROPHAGE SECRETION OF MICROMOLECULES

E. Unanue, M. Stadecker, Emil R. Unanue, 1979, Annals of the New York Academy of Sciences.

Nonspecific "lymphocyte activating" factors produced by macrophages.

E. Unanue, D. Rosenstreich, T. Diamantstein, 1979, Clinical immunology and immunopathology.

Presentation of beta-cell antigens to CD4+ and CD8+ T cells of non-obese diabetic mice.

E. Unanue, J. Shimizu, O. Kanagawa, 1993, Journal of immunology.

Secretory Function of Mononuclear Phagocytes

E. Unanue, 2007 .

Batf3-Dependent CD11blow/− Peripheral Dendritic Cells Are GM-CSF-Independent and Are Not Required for Th Cell Priming after Subcutaneous Immunization

E. Unanue, K. Murphy, J. Russell, 2011, PloS one.

EXPERIMENTAL GLOMERULONEPHRITIS. VI. THE AUTOLOGOUS PHASE OF NEPHROTOXIC SERUM NEPHRITIS.

E. Unanue, F. Dixon, 1965 .

EXPERIMENTAL GLOMERULONEPHRITIS V. STUDIES ON THE INTERACTION OF NEPHROTOXIC ANTIBODIES WITH TISSUES OF THE RAT

E. Unanue, F. Dixon, 1965 .

Nephritogenic properties of cross-reacting kidney-fixing antibodies to heart, spleen and muscle.

E. Unanue, D. Katz, F. Dixon, 1967, Journal of immunology.

Regulation of antigen-presentation-I. IFN-gamma induces antigen-presenting properties on B cells.

E. Unanue, C. Hawrylowicz, 1988, Journal of immunology.

Synthesis and secretion of a mitogenic protein by macrophages: description of a superinduction phenomenon.

E. Unanue, J. Kíely, J. Kiely, 1977, Journal of immunology.

Tumor necrosis factor is involved in the T cell-independent pathway of macrophage activation in scid mice.

E. Unanue, R. Schreiber, G. Bancroft, 1989, Journal of immunology.

Granzymes Drive a Rapid Listeriolysin O-Induced T Cell Apoptosis1

E. Unanue, H. Vivanco-Cid, Javier A. Carrero, 2008, The Journal of Immunology.

O-Induced T Cell Apoptosis Granzymes Drive a Rapid Listeriolysin

E. Unanue, Javier A. Carrero, 2008 .

Macrophage Ontogeny: Implications for Host Defence, T-lymphocyte Differentiation, and the Acquisition of Self-tolerance

E. Unanue, Christopher Y. Lu, 1985, Clinics in Immunology and Allergy.

THE FUNCTION AND REGULATION OF MACROPHAGES BEARING I-REGION-ASSOCIATED MOLECULES

E. Unanue, Christopher Y. Lu, D. Beller, 1983 .

Symbiotic relationships between macrophages and lymphocytes.

E. Unanue, 1982, Advances in experimental medicine and biology.

Receptor-mediated inactivation of early B lymphocytes

E. Unanue, C. Sidman, 1975, Nature.

Cellular studies on antigen presentation by class II MHC molecules

E. Unanue, 1992, Current Biology.

Macrophage regulation of immunity.

E. Unanue, A. Rosenthal, 1980 .

Crosslinking by ligands to surface immunoglobulin triggers mobilization of intracellular 45Ca2+ in B lymphocytes

E. Unanue, J. Braun, R. Sha’afi, 1979, The Journal of cell biology.

Capping and the lymphocyte: models for membrane reorganization.

E. Unanue, G. Schreiner, 1977, Journal of immunology.

Genetic control of ligand-induced events in B lymphocytes.

E. Unanue, C. Sidman, R. Fram, 1976, Journal of immunology.

The modulation of spontaneous and anti-Ig-stimulated motility of lymphocytes by cyclic nucleotides and adrenergic and cholinergic agents.

E. Unanue, G. Schreiner, George F. Schreiner, 1975, Journal of immunology.

LIGAND-INDUCED MOVEMENT OF LYMPHOCYTE MEMBRANE MACROMOLECULES

E. Unanue, M. Karnovsky, H. Engers, 1973, The Journal of experimental medicine.

Ligand-induced movement of lymphocyte membrane macromolecules. II. Mapping of surface moieties.

E. Unanue, M. Karnovsky, M. Leventhal, 1972, The Journal of experimental medicine.

Release of nitric oxide during the T cell-independent pathway of macrophage activation. Its role in resistance to Listeria monocytogenes.

E. Unanue, M. Mcdaniel, R. Schreiber, 1993, Journal of immunology.

Processing and presentation of hen egg-white lysozyme by macrophages.

E. Unanue, P. Allen, 1984, Immunobiology.

ListericidalNo Role for Either in Macrophage : Listeria 2-Independent Innate Immunity to MyD 88-Dependent but Toll-Like Receptor

E. Unanue, B. Edelson, 2002 .

Processing of liposome-encapsulated antigens targeted to specific subcellular compartments.

E. Unanue, C. Harding, D. Collins, 1992, Research in immunology.

Cellular mechanisms of antigen processing and the function of class I and II major histocompatibility complex molecules.

E. Unanue, C. Harding, 1990, Cell regulation.

Ontogeny of murine macrophages: functions related to antigen presentation

E. Unanue, Christopher Y. Lu, C. Lu, 1982, Infection and immunity.

Mice lacking reduced nicotinamide adenine dinucleotide phosphate oxidase activity show increased susceptibility to early infection with Listeria monocytogenes.

E. Unanue, M. Dinauer, De Vries, 1997, Journal of immunology.

IMMUNOGLOBULINS ON THE SURFACE OF LYMPHOCYTES

E. Unanue, H. Grey, P. Campbell, 1971, The Journal of experimental medicine.

IMMUNOGLOBULINS ON THE SURFACE OF LYMPHOCYTES

E. Unanue, H. Grey, P. Campbell, 1971, Journal of Experimental Medicine.

Autoimmune diabetes mellitus--much progress, but many challenges.

E. Unanue, H. Mcdevitt, 2008, Advances in immunology.

Interleukin 12 and tumor necrosis factor alpha are costimulators of interferon gamma production by natural killer cells in severe combined immunodeficiency mice with listeriosis, and interleukin 10 is a physiologic antagonist.

E. Unanue, S. Wolf, C. Tripp, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Starting in immunology by way of immunopathology.

E. Unanue, 2011, Annual review of pathology.

Failure of B lymphocytes in human blood to regenerate surface immunoglobulin after its removal by antibody.

E. Unanue, K. Ault, 1977, Journal of immunology.

Extracellular Stimulation of Intracellular Killing

E. Unanue, M. Daha, R. Furth, 1980 .

13 – Antigen Presentation by Macrophages

E. Unanue, 1988 .

The immunoregulatory role of the macrophage.

E. Unanue, P. Allen, 1987, Hospital practice.

Antigen processing and presentation at a molecular level.

E. Unanue, P. Allen, 1987, Advances in experimental medicine and biology.

The Regulatory Role of Macrophages in Infection with Intracellular Pathogens

E. Unanue, B. Babbitt, P. Allen, 1986 .

Interferon- γ -dependent regulatory circuits in immune inflammation highlighted in diabetes 1

E. Unanue, J. Mills, B. Calderon, 2009 .

Beta cells transfer vesicles containing insulin to phagocytes for presentation to T cells

E. Unanue, F. Urano, B. Zinselmeyer, 2015, Proceedings of the National Academy of Sciences.

In Autoimmune Diabetes Unique Autoreactive T Cells Recognize Insulin Peptides Generated in the Islets of Langerhans

E. Unanue, B. Calderon, S. Petzold, 2010, Nature immunology.

Absence of lymph nodes in NOD mice treated with lymphotoxin-beta receptor immunoglobulin protects from diabetes.

E. Unanue, A. Suri, M. Levisetti, 2004, Diabetes.

Autoreactivity of T cells from nonobese diabetic mice: an I-Ag7-dependent reaction.

E. Unanue, O. Kanagawa, Steven M Martin, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Accessory cell requirement in the proliferative response of T lymphocytes to hemocyanin.

E. Unanue, G. Kammer, G. M. Kammer, 1980, Clinical immunology and immunopathology.

Macrophage production of IL12 is a critical link between the innate and specific immune responses to Listeria.

E. Unanue, C. Tripp, 1995, Research in immunology.

IMMUNE COMPLEXES SUPPRESS CELLULAR IMMUNITY a

E. Unanue, H. Virgin, Emil R. Unanue, 1984, Annals of the New York Academy of Sciences.

Antigen processing and presentation by macrophages.

E. Unanue, P. Allen, 1984, The American journal of anatomy.

Control of macrophage Ia expression in neonatal mice--role of a splenic suppressor cell.

E. Unanue, Christopher Y. Lu, D. S. Snyder, 1982, Journal of immunology.

Macrophages, NK cells and neutrophils in the cytokine loop of Listeria resistance.

E. Unanue, 1996, Research in immunology.

Resident macrophages of pancreatic islets have a seminal role in the initiation of autoimmune diabetes of NOD mice

E. Unanue, B. Zinselmeyer, D. McCarthy, 2017, Proceedings of the National Academy of Sciences.

The regulation of thymidine secretion by macrophages.

E. Unanue, M. Stadecker, 1979, Journal of immunology.

Suppression of immune response to Listeria monocytogenes: mechanism(s) of immune complex suppression

E. Unanue, H. Virgin, G. Bancroft, 1985, Infection and immunity.

IA antigens and antigen-presenting function of thymic macrophages.

E. Unanue, D. Beller, 1980, Journal of immunology.

SUBPOPULATIONS OF PERITONEAL MACROPHAGES IDENTIFIED WITH ANTI-Ia SERA

E. Unanue, M. Dorf, 1978 .

Antigen-Presenting Cells

E. Unanue, 1998 .

Cutting Edge: Thymic Positive Selection and Peripheral Activation of Islet Antigen-Specific T Cells: Separation of Two Diabetogenic Steps by an I-Ag7 Class II MHC β-Chain Mutant

E. Unanue, J. Katz, O. Kanagawa, 1998, The Journal of Immunology.

An inhibitor of cell proliferation released by cultures of macrophages.

E. Unanue, R. Williams, J. Calderón, 1974, Proceedings of the National Academy of Sciences of the United States of America.

Functional and ultrastructural evidence for intracellular formation of major histocompatibility complex class II-peptide complexes during antigen processing.

E. Unanue, J. Slot, H. Geuze, 1990, Proceedings of the National Academy of Sciences of the United States of America.

Antigen presentation events during the initiation of autoimmune diabetes in the NOD mouse.

E. Unanue, Javier A. Carrero, Stephen T. Ferris, 2016, Journal of autoimmunity.

EXPERIMENTAL ALLERGIC GLOMERULONEPHRITIS INDUCED IN THE RABBIT WITH HETEROLOGOUS RENAL ANTIGENS

E. Unanue, F. Dixon, 1967, The Journal of experimental medicine.

Lymphocyte apoptosis during early phase of Listeria infection in mice.

E. Unanue, P. Swanson, B. Edelson, 1997, The American journal of pathology.

Batf3 Deficiency Reveals a Critical Role for CD8α+ Dendritic Cells in Cytotoxic T Cell Immunity

E. Unanue, M. Diamond, Whitney E. Purtha, 2008, Science.

Binding of immunogenic peptides to Ia histocompatibility molecules. 1985.

E. Unanue, E. Haber, B. Babbitt, 2005, Journal of immunology.

The distribution of Ia antigens on the surfaces of lymphocytes.

E. Unanue, M. Dorf, A. Abbas, 1976, Journal of immunology.

Chromogranin A Deficiency Confers Protection From Autoimmune Diabetes via Multiple Mechanisms

E. Unanue, L. Teyton, K. Haskins, 2021, Diabetes.

Control of proliferation and differentiation in B lymphocytes by anti-Ig antibodies and a serum-derived cofactor.

E. Unanue, C. Sidman, Emil R. Unanue, 1978, Proceedings of the National Academy of Sciences of the United States of America.

Secondary response to Listeria infection requires IFN-gamma but is partially independent of IL-12.

E. Unanue, O. Kanagawa, C. Tripp, 1995, Journal of immunology.

Immune complex effects on murine macrophages. I. Immune complexes suppress interferon-gamma induction of Ia expression.

E. Unanue, H. Virgin, G. Wittenberg, 1985, Journal of immunology.

Regulation of macrophage populations. IV. Modulation of Ia expression in bone marrow-derived macrophages.

E. Unanue, D. Beller, E. G. Calamai, 1982, Journal of immunology.

Studies on the distribution of surface immunoglobulins of human B-lymphocytes.

E. Unanue, M. Karnovsky, K. Ault, 1973, The Journal of clinical investigation.

The modulation of lymphocyte functions by molecules secreted by macrophages. II. Conditions leading to increased secretion

E. Unanue, J. Kíely, J. Calderón, 1976, The Journal of experimental medicine.

Costimulatory Pathways CD40-CD40 Ligand and B7-CD28-CTLA-4 Minor Epitopes of Lysozyme Is Not Affected by Cells Responding to Chemically Dominant or Cutting Edge: The Relative Distribution of T

E. Unanue, R. DiPaolo, 2002 .

The resident macrophages in murine pancreatic islets are constantly probing their local environment, capturing beta cell granules and blood particles

E. Unanue, B. Zinselmeyer, B. Saunders, 2018, Diabetologia.

The concept of antigen processing and presentation

E. Unanue, 1995 .

Relationship between beta cell injury and antigen presentation in NOD mice.

E. Unanue, J. Shimizu, O. Kanagawa, 1995, Journal of immunology.

Antigen-binding cells. I. Their idenification and role in the immune response.

E. Unanue, 1971, Journal of immunology.

Endogenous IL-1 is required for neutrophil recruitment and macrophage activation during murine listeriosis.

E. Unanue, R. Schreiber, C. Tripp, 1994, Journal of immunology.

Thymic macrophages modulate one stage of T cell differentiation in vitro.

E. Unanue, D. Beller, 1978, Journal of immunology.

The presence of I-region-associated antigens on B cells in molecules distinct from immunoglobulin and H-2K and H-2D.

E. Unanue, B. Benacerraf, M. Dorf, 1974, Proceedings of the National Academy of Sciences of the United States of America.

EXPERIMENTAL GLOMERULONEPHRITIS. IV. PARTICIPATION OF COMPLEMENT IN NEPHROTOXIC NEPHRITIS.

E. Unanue, F. Dixon, 1964 .

Immunol . Lymphocytes . Region-Restricted Antigen Presentation to T Antigen-Processing Event Required for I-Pillars Article : Identification of a Macrophage

E. Unanue, K. Ziegler, 2001 .

Introduction of intravascular coagulation and focal tissue necrosis in rats by administration of anti-connective tissue antibodies.

E. Unanue, D. Katz, F. Dixon, 1968, The American journal of pathology.

Impact of lymphocyte apoptosis on the innate immune stages of infection

E. Unanue, Javier A. Carrero, 2007, Immunologic research.

Redistribution and Fate of Ig Complexes on Surface of B Lymphocytes: Functional Implications and Mechanisms

E. Unanue, M. Karnovsky, Emil R. Unanue, 1973, Transplantation reviews.

Synthesis and release of thymidine by macrophages.

E. Unanue, M. L. Karnovsky, M. Stadecker, 1977, Journal of immunology.

Spontaneous T-cell lymphokine production and enhanced macrophage Ia expression and tumoricidal activity in MRL-lpr mice.

E. Unanue, C. Lu, C. Lu, 1982, Clinical immunology and immunopathology.

Evidence that thymocytes require at least two distinct signals to proliferate.

E. Unanue, D. Beller, 1979, Journal of immunology.

Interleukin 1 participates in the development of anti-Listeria responses in normal and SCID mice.

E. Unanue, R. Schreiber, L. Brunt, 1992, Proceedings of the National Academy of Sciences of the United States of America.

QUANTITATION OF GENETICALLY RESTRICTED T CELL-MACROPHAGE BINDING1

E. Unanue, K. Ziegler, 1980 .

T CELL-MACROPHAGE INTERACTION IN INFECTION TO THE INTRACELLULAR PATHOGEN LISTERIA MONOCYTOGENES

E. Unanue, 1980 .

Multiple Interactions Between Listeria-Immune T Lymphocytes and Macrophages: Regulation by the Major Histocompatibility Gene Complex

E. Unanue, A. Farr, D. Mcclelland, 1980 .

The specific binding of Listeria monocytogenes-immune T lymphocytes to macrophages. I. Quantitation and role of H-2 gene products

E. Unanue, K. Ziegler, 1979, The Journal of experimental medicine.

Listeriolysin O from Listeria monocytogenes Is a Lymphocyte Apoptogenic Molecule1

E. Unanue, Javier A. Carrero, B. Calderon, 2004, The Journal of Immunology.

THE IMMUNOGENICITY OF ANTIGEN BOUND TO THE PLASMA MEMBRANE OF MACROPHAGES

E. Unanue, J. Cerottini, 1970, The Journal of experimental medicine.

Immune complex effects on murine macrophages. II. Immune complex effects on activated macrophages cytotoxicity, membrane IL 1, and antigen presentation.

E. Unanue, H. Virgin, E. Kurt-Jones, 1985, Journal of immunology.

Suppression of the immune response to Listeria monocytogenes. I. Immune complexes inhibit resistance.

E. Unanue, H. Virgin, 1984, Journal of immunology.

Pathology of Listeria infection in murine severe combined immunodeficiency. A study by immunohistochemistry and electron microscopy.

E. Unanue, G. Bancroft, G. Bosma, 1988, Laboratory investigation; a journal of technical methods and pathology.

A carbohydrate antigen linked to a T-cell immunogenic peptide induces T-cell clones selective for carbohydrate

E. Unanue, J. Kihlberg, C. Harding, 1993 .

Two biological activities regulating cell proliferation found in cultures of peritoneal exudate cells

E. Unanue, J. Calderón, 1975, Nature.

The macrophage as a regulator of lymphocyte function.

E. Unanue, 1979, Hospital practice.

Genetic and Pharmacologic Studies

E. Unanue, F. Rosen, J. Braun, 1980 .

Type I Interferon Sensitizes Lymphocytes to Apoptosis and Reduces Resistance to Listeria Infection

E. Unanue, Javier A. Carrero, B. Calderon, 2004, The Journal of experimental medicine.

A Membrane form of IL-1 — Identification and Control of Expression

E. Unanue, C. Weaver, D. Chaplin, 1987 .

Capping and adenosine metabolism. Genetic and pharmacologic studies

E. Unanue, F. Rosen, J. Braun, 1980, The Journal of experimental medicine.

Anti-Ig-triggered movements of lymphocytes-specificity and lack of evidence for directional migration.

E. Unanue, G. Schreiner, 1975, Journal of immunology.

Liga-nd-induced M O V E M E N T of v. Capping, Cell Movement, and Microtubular Function in Normal and Lectin-treated Lymphocytes*

E. Unanue, M. Karnovsky, Morris J. Karnovsky, 2022 .

Interleukin 1 is processed and released during apoptosis.

E. Unanue, K. Hogquist, D. Chaplin, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Mechanisms and immunological effects of apoptosis caused by Listeria monocytogenes.

E. Unanue, Javier A. Carrero, 2012, Advances in immunology.

Inter-relationship among macrophages, natural killer cells and neutrophils in early stages of Listeria resistance.

E. Unanue, Emil R. Unanue, 1997, Current opinion in immunology.

Membrane and cytoplasmic changes in B lymphocytes induced by ligand-surface immunoglobulin interaction.

E. Unanue, G. Schreiner, 1976, Advances in immunology.

Thymic maturation in vitro by a secretory product from macrophages.

E. Unanue, D. Beller, 1977, Journal of immunology.

Effects of bacterial products on lymphocytes and macrophages: their possible role in natural resistance to listeria infetion in mice.

E. Unanue, J. Petit, 1974, Journal of immunology.

The function of macrophages in the immune response.

E. Unanue, J. Cerottini, 1970, Seminars in hematology.

A role of macrophages in the stimulation of immune responses by adjuvants.

E. Unanue, A. Allison, B. Askonas, 1969, Journal of immunology.

Inhibition of surface capping of macromolecules by local anaesthetics and tranquillisers

E. Unanue, M. Karnovsky, G. Ryan, 1974, Nature.

Immunologic events during Listeria monocytogenes infection in mice: adjuvanticity and immunogenicity of macrophage-bound antigens.

E. Unanue, F. Lane, 1973, Journal of Immunology.

The Regulation of Lymphocyte Functions by the Macrophage

E. Unanue, 1978, Immunological reviews.

Activated macrophages induce vascular proliferation

E. Unanue, R. Cotran, M. Gimbrone, 1977, Nature.

Marked increase in Ia-bearing macrophages during Trypanosoma cruzi infection.

E. Unanue, K. Behbehani, S. Pan, 1981, Clinical immunology and immunopathology.

Induction of cytocidal macrophages after in vitro interactions between Listeria-immune T cells and macrophages--role of H-2.

E. Unanue, A. Farr, W. Wechter, 1979, Journal of immunology.

The release of antigen molecules from macrophages: characterization of the phenomena.

E. Unanue, J. Calderón, 1974, Journal of immunology.

The regulatory role of macrophages in antigenic stimulation.

E. Unanue, 1972, Advances in immunology.

Antigen-presenting function of the macrophage.

E. Unanue, 1984, Annual review of immunology.

Macrophage Activation by Interferon or Interferon Inducers

E. Unanue, M. Daha, M. Rabinovitch, 1980 .

Variations in MHC Class II Antigen Processing and Presentation in Health and Disease.

E. Unanue, J. Neefjes, V. Turk, 2016, Annual review of immunology.

TREM2 Maintains Microglial Metabolic Fitness in Alzheimer’s Disease

Maxim N. Artyomov, E. Unanue, D. Holtzman, 2017, Cell.

Quantitative analysis of the T cell repertoire that escapes negative selection.

E. Unanue, D. Peterson, R. DiPaolo, 1999, Immunity.

The lymphocyte cytoskeleton and its control of surface receptor functions.

E. Unanue, J. Braun, 1983, Seminars in hematology.

Spontaneous redistribution of surface immunoglobulin in the motile B lymphocyte

E. Unanue, J. Braun, G. Schreiner, 1976, The Journal of experimental medicine.

Development of B lymphocytes. I. Cell populations and a critical event during ontogeny.

E. Unanue, C. Sidman, 1975, Journal of immunology.

Genetic control of the immune response of mice to hemocyanin. I. Th role of macrophages.

E. Unanue, J. Cerottini, 1971, Journal of immunology.

Macrophages: Their Role in the Induction of Immunity

E. Unanue, M. Feldman, 1971 .

Persistence of Antigen on the Surface of Macrophages

E. Unanue, J. Cerottini, M. Bedford, 1969, Nature.

Diabetes is predicted by the beta cell level of autoantigen.

E. Unanue, G. Schweitzer, C. Byersdorfer, 2005, Journal of immunology.

The Effect of Complement on the Degradation of Soluble Immune Aggregates by Kupffer Cells and Peritoneal Macrophages in Vitro

E. Unanue, M. Daha, A. Kijlstra, 1980 .

A mAb recognizing a surface antigen of Mycobacterium tuberculosis enhances host survival.

E. Unanue, A. Casadevall, Bing Chen, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Alpha-fetoprotein inhibits macrophage expression of Ia antigens.

E. Unanue, P. Changelian, C. Lu, 1984, Journal of immunology.

AN ULTRASTRUCTURAL STUDY OF LYMPHOCYTES WITH SURFACE-BOUND IMMUNOGLOBULIN

E. Unanue, M. Karnovsky, W. Perkins, 1972, The Journal of experimental medicine.

The murine diabetogenic class II histocompatibility molecule I-Ag7: structural and functional properties and specificity of peptide selection.

E. Unanue, A. Suri, 2005, Advances in immunology.

Specificity of peptide selection by antigen-presenting cells homozygous or heterozygous for expression of class II MHC molecules: The lack of competition

E. Unanue, M. Gross, O. Kanagawa, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Blood leukocytes recapitulate diabetogenic peptide–MHC-II complexes displayed in the pancreatic islets

Cheryl F. Lichti, E. Unanue, A. Arbeláez, 2021, The Journal of experimental medicine.

The Immunoreactive Platform of the Pancreatic Islets Influences the Development of Autoreactivity

E. Unanue, Xiaoxiao Wan, 2019, Diabetes.

Antigen recognition in autoimmune diabetes: a novel pathway underlying disease initiation

E. Unanue, Xiaoxiao Wan, 2018, Precision clinical medicine.

Macrophages in Endocrine Glands, with Emphasis on Pancreatic Islets

E. Unanue, 2016, Microbiology spectrum.

and Determined by the Amino Acid Changes the Diabetogenic I-Ag7 Molecule Are Unique In APCs, the Autologous Peptides Selected by

Emil R. Unanue, Michael L. Gross, Anish Suri, 2013 .

Prediction of HLA-DQ8 β cell peptidome using a computational program and its relationship to autoreactive T cells

Emil R. Unanue, Kuan Y. Chang, E. Unanue, 2009, International immunology.

First Signature of Islet β-Cell-Derived Naturally Processed Peptides Selected by Diabetogenic Class II MHC Molecules1

E. Unanue, M. Gross, H. Rohrs, 2008, The Journal of Immunology.

Diabetogenic Class II MHC Molecules Naturally Processed Peptides Selected by-Cell-Derived β First Signature of Islet Gross and

E. Unanue, M. Gross, H. Rohrs, 2008 .

Perspective on antigen processing and presentation

E. Unanue, 2002, Immunological reviews.

Rous-Whipple Award Lecture. Chemical features of peptide selection by the class II histocompatibility molecules.

E. Unanue, Emil R. Unanue, 1999, The American journal of pathology.

Podocytes use FcRn to clear IgG from the glomerular basement membrane

Emil R. Unanue, Jeffrey H. Miner, Jeffrey B. Kopp, 2008, Proceedings of the National Academy of Sciences.

Some Old and Some New Findings on Antigen Processing and Presentation

E. Unanue, 2006 .

T‐Cell Recognition of Lysozyme: The Biochemical Basis of Presentation

E. Unanue, B. Babbitt, P. Allen, 1987, Immunological reviews.

Biochemistry and biology of antigen presentation by macrophages.

E. Unanue, P. Allen, 1986, Cellular immunology.

Molecular Nature of T Cell Recognition of Antigen

E. Unanue, P. Allen, E. Kurt-Jones, 1985 .

Intracellular antibody neutralizes Listeria growth.

E. Unanue, B. Edelson, Emil R. Unanue, 2001, Immunity.

Cutting edge: paradigm revisited: antibody provides resistance to Listeria infection.

E. Unanue, P. Cossart, B. Edelson, 1999, Journal of immunology.

Single-cell RNA sequencing of murine islets shows high cellular complexity at all stages of autoimmune diabetes

E. Unanue, Xiaoxiao Wan, Hao Hu, 2020, The Journal of experimental medicine.

Identification of a membrane-associated interleukin 1 in macrophages.

E. Unanue, S. Mizel, E. Kurt-Jones, 1985, Proceedings of the National Academy of Sciences of the United States of America.

CD8α(+) dendritic cells are an obligate cellular entry point for productive infection by Listeria monocytogenes.

Mark J. Miller, E. Unanue, R. Schreiber, 2011, Immunity.

Processing and Presentation of Antigen by the Class II Histocompatibility System

E. Unanue, 2010 .

Mechanisms and consequences of peptide selection by the I‐Ak class II molecule

E. Unanue, R. Latek, 1999, Immunological reviews.

Characterization and quantitation of peptide-MHC complexes produced from hen egg lysozyme using a monoclonal antibody.

E. Unanue, C. Nelson, G. Dadaglio, 1997, Immunity.

Amino acid residues on the I-Ak alpha-chain required for the binding and stability of two antigenic peptides.

E. Unanue, C. Nelson, N. Viner, 1996, Journal of immunology.

Monoclonal antibodies to murine IL-1 alpha. Production, characterization, and inhibition of membrane-associated IL-1 activity.

E. Unanue, R. Schreiber, D. Chaplin, 1988, Journal of immunology.

ROLE OF MACROPHAGES IN THE REGULATION OF THYMOCYTE PROLIFERATION AND DIFFERENTIATION1

E. Unanue, D. Beller, 1980 .

The MHCII peptidome of the pancreatic islet identifies key features of autoimmune peptides

Cheryl F. Lichti, E. Unanue, A. Chervonsky, 2020, Nature Immunology.

MHC-II neoantigens shape tumor immunity and response to immunotherapy

Cheryl F. Lichti, E. Unanue, T. Jacks, 2019, Nature.

Pancreatic islets communicate with lymphoid tissues via exocytosis of insulin peptides

Mark S. Anderson, Cheryl F. Lichti, E. Unanue, 2018, Nature.

Processing of proteins in autophagy vesicles of antigen-presenting cells generates citrullinated peptides recognized by the immune system

E. Unanue, Jamie M. Ireland, 2012, Autophagy.

Unique features in the presentation of insulin epitopes in autoimmune diabetes: an update.

E. Unanue, Xiaoxiao Wan, 2017, Current opinion in immunology.

A novel pathway of presentation by class II-MHC molecules involving peptides or denatured proteins important in autoimmunity.

E. Unanue, James F. Mohan, 2013, Molecular immunology.

CD2-Associated Protein Haploinsufficiency Is Linked to Glomerular Disease Susceptibility

E. Unanue, C. Winkler, A. Shaw, 2003, Science.

Cytocidal macrophages in symbiosis with CD4 and CD8 T cells cause acute diabetes following checkpoint blockade of PD-1 in NOD mice

E. Unanue, Orion J. Peterson, Hao Hu, 2020, Proceedings of the National Academy of Sciences.

TREM2 Modulation Remodels the Tumor Myeloid Landscape Enhancing Anti-PD-1 Immunotherapy

Maxim N. Artyomov, E. Unanue, C. Fronick, 2020, Cell.

Natural Immunity: A T‐Cell‐Independent Pathway of Macrophage Activation, Defined in the scid Mouse

E. Unanue, R. Schreiber, G. Bancroft, 1991, Immunological reviews.

Binding of immunogenic peptides to Ia histocompatibility molecules

E. Unanue, E. Haber, B. Babbitt, 1985, Nature.

Evaluation of the role of macrophages in immune induction.

E. Unanue, J. Calderón, 1975, Federation proceedings.

Respiratory Pathways of Macrophages — Cellular Localization and Relation to Cidal Activity

E. Unanue, M. Daha, J. A. Badwey, 1980 .

Listeria monocytogenes induces an interferon‐enhanced activation of the integrated stress response that is detrimental for resolution of infection in mice

E. Unanue, F. Urano, Javier A. Carrero, 2017, European journal of immunology.

Immunologic events in experimental hypersensitivity granulomas.

E. Unanue, B. Benacerraf, Emil R. Unanue, 1973, The American journal of pathology.

The disruption of immunoglobulin caps by local anesthetics.

E. Unanue, G. Schreiner, 1976, Clinical immunology and immunopathology.

The effects of beryllium and other adjuvants on Ia expression by macrophages.

E. Unanue, K. Behbehani, D. Beller, 1985, Journal of immunology.

Identification of two distinct properties of class II major histocompatibility complex-associated peptides.

E. Unanue, C. Nelson, S. Petzold, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Antigen binding cells. II. Effect of highly radioactive antigen on the immunologic function of bone marrow cells.

E. Unanue, 1971, Journal of immunology.

Regulation of lymphocyte proliferation and differentiation by macrophages.

E. Unanue, A. Farr, D. Beller, 1978, Federation proceedings.

Nephrotoxic serum nephritis in complement intact and deficient mice.

E. Unanue, M. Mardiney, F. Dixon, 1967, Journal of immunology.

Glomerular injury: functional and phenotypic characteristics of resident and infiltrating macrophages

E. Unanue, R. Cotran, G. Schreiner, 1985 .

Identification of the T-cell and Ia contact residues of a T-cell antigenic epitope

E. Unanue, G. Marshall, P. Allen, 1987, Nature.

The lack of consensus for I-A(g7)-peptide binding motifs: is there a requirement for anchor amino acid side chains?

E. Unanue, O. Kanagawa, E R Unanue, 1999, Proceedings of the National Academy of Sciences of the United States of America.

RNA sensor-induced type I IFN prevents diabetes caused by a β cell-tropic virus in mice.

E. Unanue, M. Diamond, M. Colonna, 2011, The Journal of clinical investigation.

Lymphocytes are detrimental during the early innate immune response against Listeria monocytogenes

E. Unanue, Javier A. Carrero, B. Calderon, 2006, The Journal of experimental medicine.

Mapping and migration of lymphocyte surface macromolecules.

E. Unanue, M. Karnovsky, 1973, Federation proceedings.

Antigenic competition at the level of peptide-Ia binding.

E. Unanue, E. Haber, B. Babbitt, 1986, Proceedings of the National Academy of Sciences of the United States of America.

Cutting Edge: A Single MHC Anchor Residue Alters the Conformation of a Peptide-MHC Complex Inducing T Cells That Survive Negative Selection1

E. Unanue, D. Peterson, R. DiPaolo, 2001, The Journal of Immunology.

The central role of antigen presentation in islets of Langerhans in autoimmune diabetes.

E. Unanue, Javier A. Carrero, B. Calderon, 2014, Current opinion in immunology.

ANTIGEN BINDING AND CAPPING BY LYMPHOCYTES OF GENETIC NONRESPONDER MICE

E. Unanue, B. Benacerraf, E. Dunham, 1972, Journal of Experimental Medicine.

Role of macrophages in the immune response.

E. Unanue, B. Askonas, I. Auzins, 1968, Bulletin de la Societe de chimie biologique.

Complexes generated by the binding of free peptides to class II MHC molecules are antigenically diverse compared with those generated by intracellular processing.

E. Unanue, C. Nelson, N. Viner, 1996, Journal of immunology.

Targeting proteins to distinct subcellular compartments reveals unique requirements for MHC class I and II presentation

E. Unanue, R. Belizaire, 2009, Proceedings of the National Academy of Sciences.

Neutralization of IL-12 decreases resistance to Listeria in SCID and C.B-17 mice. Reversal by IFN-gamma.

E. Unanue, M. Gately, C. Tripp, 1994, Journal of immunology.

The class II MHC I-Ag7 molecules from non-obese diabetic mice are poor peptide binders.

E. Unanue, J. Shimizu, O. Kanagawa, 1996, Journal of immunology.

Identification of naturally processed peptides bound to the class I MHC molecule H‐2Kd of normal and TAP‐deficient cells

E. Unanue, A. Suri, M. Levisetti, 2006, European journal of immunology.

Altered Peptide Ligands Make Their Entry

Emil R. Unanue, E. Unanue, 2011, The Journal of Immunology.

E V E N T S a F T E R T H E B I N D I N G of a N T I G E N to Removal and Regeneration of the Antigen Receptor*

E. Unanue, K. Ault, 2022 .

Interaction of macrophages and lymphocytes with surface immunoglobulin.

E. Unanue, J. Schmidtke, 1971, Nature: New biology.

The immune response of mice to keyhole limpet hemocyanin bound to macrophages.

E. Unanue, 1969, Journal of immunology.

The wide diversity and complexity of peptides bound to class II MHC molecules.

Emil R Unanue, E. Unanue, Scott B. Lovitch, 2006, Current opinion in immunology.

Interrelationships of surface immunoglobulin and Fc receptors on mouse B lymphocytes.

E. Unanue, A. Abbas, Abul K. Abbas, 1975, Journal of immunology.

Function of Surface Immunoglobulin of B Lymphocytes

E. Unanue, 1979 .

13 – Structure and function of surface immunoglobulin of lymphocytes

E. Unanue, G. Schreiner, 1977 .

Functional Redundancy between Thymic CD8α+ and Sirpα+ Conventional Dendritic Cells in Presentation of Blood-Derived Lysozyme by MHC Class II Proteins

E. Unanue, K. Murphy, D. F. Atibalentja, 2011, The Journal of Immunology.

Thymus-Blood Protein Interactions Are Highly Effective in Negative Selection and Regulatory T Cell Induction1

E. Unanue, C. Byersdorfer, D. F. Atibalentja, 2009, The Journal of Immunology.

Do the peptide-binding properties of diabetogenic class II molecules explain autoreactivity?

E. Unanue, A. Suri, M. Levisetti, 2008, Current opinion in immunology.

Antigen receptor engagement delivers a stop signal to migrating T lymphocytes.

D A Peterson, E. Unanue, S. Bromley, 1997, Proceedings of the National Academy of Sciences of the United States of America.

CTLA-4 suppresses the pathogenicity of self antigen–specific T cells by cell-intrinsic and cell-extrinsic mechanisms

E. Unanue, K. Murphy, Hyang-Mi Lee, 2010, Nature Immunology.

Regulation of macrophage Ia expression in vivo and in vitro.

E. Unanue, D. Beller, 1982, Advances in Experimental Medicine and Biology.

Characterization of accessory cell costimulation of Th1 cytokine synthesis.

E. Unanue, I. Williams, 1991, Journal of immunology.

Amino-Terminal Flanking Residues Determine the Conformation of a Peptide–Class II MHC Complex1

Zheng Pu, Emil R. Unanue, E. Unanue, 2006, The Journal of Immunology.

A negatively charged anchor residue promotes high affinity binding to the MHC class II molecule I-Ak.

E. Unanue, C. Nelson, N. Viner, 1996, Journal of immunology.

Identification of the naturally processed form of hen egg white lysozyme bound to the murine major histocompatibility complex class II molecule I-Ak.

E. Unanue, C. Nelson, D. McCourt, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Quantitation of Lysozyme Peptides Bound to Class II MHC Molecules Indicates Very Large Differences in Levels of Presentation1

E. Unanue, R. DiPaolo, C. Velazquez, 2001, The Journal of Immunology.

Large Differences in Levels of Presentation Class II MHC Molecules Indicates Very Quantitation of Lysozyme Peptides Bound to

E. Unanue, R. DiPaolo, C. Velazquez, 2001 .

Isolation and quantitation of a minor determinant of hen egg white lysozyme bound to I-Ak by using peptide-specific immunoaffinity.

E. Unanue, C. Nelson, I. Vidavsky, 1998, Journal of immunology.

Immunoaffinity by Using Peptide-Specific k Bound to I-A Determinant of Hen Egg White Lysozyme Isolation and Quantitation of a Minor

E. Unanue, C. Nelson, I. Vidavsky, 1998 .

Distinct recognition by two subsets of T cells of an MHC class II-peptide complex

E. Unanue, Javier A. Carrero, Z. Pu, 2002, Proceedings of the National Academy of Sciences of the United States of America.

EXPERIMENTAL ALLERGIC GLOMERULONEPHRITIS INDUCED IN THE RABBIT WITH HOMOLOGOUS RENAL ANTIGENS

E. Unanue, F. Dixon, J. D. Feldman, 1967, The Journal of experimental medicine.

Antigen presentation

E. Unanue, Scott B. Lovitch, Javier A. Carrero, 2005, Immunologic research.

Chemical Identification of a Low Abundance Lysozyme Peptide Family Bound to I-Ak Histocompatibility Molecules*

E. Unanue, I. Vidavsky, M. Gross, 2002, The Journal of Biological Chemistry.

Differential requirements for antigen processing by macrophages for lysozyme-specific T cell hybridomas.

E. Unanue, P. Allen, 1984, Journal of immunology.

Dendritic Cells Process and Present Antigens Across A Range of Maturation States1

E. Unanue, M. Colonna, M. Cella, 2003, The Journal of Immunology.

Costimulatory requirements of murine Th1 clones. The role of accessory cell-derived signals in responses to anti-CD3 antibody.

E. Unanue, I. Williams, 1990, Journal of immunology.

Regulation of macrophage populations. III. The immunologic induction of exudates rich in Ia-bearing macrophages is a radiosensitive process.

E. Unanue, D. Beller, M. Scher, 1982, Journal of immunology.

IL-1 gene expression in lymphoid tissues.

E. Unanue, L. M. Duncan, L. S. Meegan, 1991, Journal of immunology.

EXPERIMENTAL GLOMERULONEPHRITIS

E. Unanue, F. Dixon, 1965, The Journal of experimental medicine.

Phagocytosis in the retina promotes local insulin production in the eye

E. Unanue, J. Ambati, B. Kundu, 2023, Nature Metabolism.

Viral infections and nonspecific protection--good or bad?

E. Unanue, 2007, The New England journal of medicine.

Functional and structural studies on clathrin triskelions and baskets.

E. Unanue, D. Branton, E. Ungewickell, 1982, Cold Spring Harbor symposia on quantitative biology.

Endoplasmic Reticulum: An Interface Between the Immune System and Metabolism

E. Unanue, F. Urano, 2013, Diabetes.

Requirements for mitogenic stimulation of murine B cells by soluble anti-IgM antibodies.

E. Unanue, C. Sidman, 1979, Journal of immunology.

Pathogenesis of experimental allergic orchitis. II. The role of antibody.

E. Unanue, K. Tung, F. Dixon, 1971, Journal of immunology.

Pathogenesis of experimental allergic orchitis. I. Transfer with immune lymph node cells.

E. Unanue, K. Tung, F. Dixon, 1971, Journal of immunology.

Peptides determine the lifespan of MHC class II molecules in the antigen-presenting cell

Emil R. Unanue, E. Unanue, C. Nelson, 1994, Nature.

The islet-resident macrophage is in an inflammatory state and senses microbial products in blood

Maxim N. Artyomov, E. Unanue, M. Artyomov, 2017, The Journal of experimental medicine.

The immunopathology of experimental allergic orchitis.

E. Unanue, K. Tung, F. Dixon, 1970, The American journal of pathology.

Antigen recognition Editorial overview

E. Unanue, J. Cerottini, 1991 .

Depletion of islet resident macrophages protects mice from type 1 diabetes

E. Unanue, B. Zinselmeyer, D. McCarthy, 2018, Journal of Immunology.

Presentation of Type B Peptide–MHC Complexes from Hen Egg White Lysozyme by TLR Ligands and Type I IFNs Independent of H2-DM Regulation

E. Unanue, Beverly S. I. Strong, 2011, The Journal of Immunology.

Independent of H 2-DM Regulation by TLR Ligands and Type I IFNs Complexes from Hen Egg White Lysozyme MHC − Presentation of Type B Peptide

E. Unanue, Beverly S. I. Strong, 2011 .

Defining the Transcriptional and Cellular Landscape of Type 1 Diabetes in the NOD Mouse

E. Unanue, M. Artyomov, Javier A. Carrero, 2013, PloS one.

Results Examination of Islets of Langerhans Reveals a Progressive Entry of Leukocytes Subsets Throughout Diabetogenesis

E. Unanue, M. Artyomov, Javier A. Carrero, 2013 .

Antigen presentation events in autoimmune diabetes.

E. Unanue, B. Calderon, 2012, Current opinion in immunology.

Cell surface changes in capping studied by correlated fluorescence and scanning electron microscopy.

E. Unanue, M. Karnovsky, 1978, Laboratory investigation; a journal of technical methods and pathology.

Membrane IL-1: a key protein in antigen presentation.

E. Unanue, C. Weaver, D. Chaplin, 1987, Annales de l'Institut Pasteur. Immunology.

This information is current as Infection Listeria Provides Resistance to Cutting Edge : Paradigm Revisited : Antibody

E. Unanue, P. Cossart, B. Edelson, 1999 .

EXPERIMENTAL GLOMERULONEPHRITIS VII. THE ABSENCE OF AN AUTOIMMUNE ANTIKIDNEY RESPONSE IN NEPHROTOXIC SERUM NEPHRITIS

E. Unanue, F. Dixon, J. D. Feldman, 1965 .

The immune capacity of lymphocytes after cross-linking of surface immunoglobulin receptors by antibody.

E. Unanue, D. Katz, D. H. Katz, 1972, Journal of immunology.

LIGAND-INDUCED MOVEMENT OF LYMPHOCYTE MEMBRANE MACROMOLECULES

E. Unanue, M. Karnovsky, 1974, The Journal of experimental medicine.

Thymus dependency of the immune response to hemocyanin: an evaluation of the role of macrophages in thymectomized mice.

E. Unanue, 1970, Journal of immunology.

IFN-gamma-dependent regulatory circuits in immune inflammation highlighted in diabetes.

E. Unanue, J. Mills, B. Calderon, 2008, Journal of Immunology.

Following Immunization Antigen Becomes Concentrated in a Limited Number of APCs Including B Cells

E. Unanue, R. DiPaolo, S. Petzold, 2004, The Journal of Immunology.

I. Distribution and Quantitation*

E. Unanue, H. Grey, S. Colon, 2022 .

Is a Lymphocyte Apoptogenic Molecule Listeriolysin O from Listeria monocytogenes

E. Unanue, Javier A. Carrero, B. Calderon, 2013 .

Is a Lymphocyte Apoptogenic Molecule Listeria monocytogenes Listeriolysin O from

E. Unanue, Javier A. Carrero, B. Calderon, 2004 .

Proliferative response to anti-IgM antibodies of various B lymphocyte subpopulations isolated by cell sorting.

E. Unanue, C. Sidman, 1978, Journal of Immunology.

The Mouse Mutant “Motheaten”

E. Unanue, L. Shultz, C. Sidman, 1978, The Journal of Immunology.

APCs Present Aβk-Derived Peptides That Are Autoantigenic to Type B T Cells1

E. Unanue, M. Gross, Scott B. Lovitch, 2003, The Journal of Immunology.

APCs present A beta(k)-derived peptides that are autoantigenic to type B T cells.

E. Unanue, M. Gross, Scott B. Lovitch, 2003, Journal of immunology.

Thymic positive selection and peripheral activation of islet antigen-specific T cells: separation of two diabetogenic steps by an I-A(g7) class II MHC beta-chain mutant.

E. Unanue, J. Katz, O. Kanagawa, 1998, Journal of immunology.

Independent Selection by I-Ak Molecules of Two Epitopes Found in Tandem in an Extended Polypeptide Antigen1

E. Unanue, I. Vidavsky, K. van der Drift, 2000, The Journal of Immunology.

Extended Polypeptide Antigen Two Epitopes Found in Tandem in an Molecules ofkIndependent Selection

Koen van der Drift, E. Unanue, I. Vidavsky, 2000 .

EXPERIMENTAL GLOMERULONEPHRITIS

E. Unanue, F. Dixon, 1965, The Journal of experimental medicine.

Autoregulation of B cell growth by an immunoglobulin M autoantibody.

E. Unanue, J. Braun, J. Kiely, 1985, Journal of Immunology.

Propagation of B lymphocytes in vitro.

E. Unanue, J. Braun, J. Kiely, 1984, Current topics in microbiology and immunology.

EXPERIMENTAL GLOMERULONEPHRITIS

E. Unanue, F. Dixon, 1965, The Journal of experimental medicine.

Mechanisms and Functions of Capping in Lymphocytes

E. Unanue, K. Ault, 1980 .

EXPERIMENTAL GLOMERULONEPHRITIS

E. Unanue, F. Dixon, J. D. Feldman, 1965, The Journal of experimental medicine.

EXPERIMENTAL GLOMERULONEPHRITIS VII. TRE ABSENCE OF AN AIYT0rMMIYNE ANTIKIDNEY RESPONSE IN NEPIIROTOXIC SERUM NEPIIRITIS*, BY EMIL

E. Unanue, F. Dixon, 2003 .

Expression of membrane interleukin 1 by fibroblasts transfected with murine pro-interleukin la cDNA ( cytokines / gene transfer / protein processing / macrophages )

E. Unanue, R. Fuhlbrigge, Steven M. FINEt, 2022 .

Type I and II Interferon Receptors Differentially Regulate Type 1 Diabetes Susceptibility in Male Versus Female NOD Mice

E. Unanue, Javier A. Carrero, N. Benshoff, 2018, Diabetes.

Antigen-binding function of class II MHC molecules.

E. Unanue, C. Harding, I. Luescher, 1989, Cold Spring Harbor symposia on quantitative biology.

[Immunogenicity of two antigens completely endocytic in macrophages].

E. Unanue, A. Cruchaud, 1972, Schweizerische medizinische Wochenschrift.

Comparison of the two types of immunoglobulin-bearing lymphocytes in human blood with regard to capping and motility.

E. Unanue, K. Ault, 1977, Clinical immunology and immunopathology.

Immunology at 2000.

E. Unanue, R. Schreiber, K. Murphy, 1999, Immunity.

Innate Immunity in Bacterial Infections

E. Unanue, 2002 .

B Lymphocyte Biology Studied with Anti‐Ig Antibodies

E. Unanue, J. Braun, Emil R. Unanue, 1980, Immunological reviews.

Surface immunoglobulin and the lymphocyte cytoskeleton.

E. Unanue, J. Braun, 1983, Federation proceedings.

Predicting peptides bound to I‐Ag7 class II histocompatibility molecules using a novel expectation‐maximization alignment algorithm

Anish Suri, Kuan Y Chang, Emil R Unanue, 2007, Proteomics.

18 Interaction of Pathogens with the Innate and Adaptive Immune System

E. Unanue, E. D. Gregorio, 2004 .

The role of islet antigen presenting cells and the presentation of insulin in the initiation of autoimmune diabetes in the NOD mouse

E. Unanue, Javier A. Carrero, Stephen T. Ferris, 2016, Immunological reviews.

Identification of Cross Reactive Insulin Immunogenic Epitopes from Commensal Gut Microbes

E. Unanue, C. Kahn, Emrah Altindis, 2018, Diabetes.

LIGAND-INDUCED MOVEMENT OF LYMPHOCYTE MEMBRANE MACROMOLECITLES

E. Unanue, M. Karnovsky, M. Leventhal, 1972, The Journal of experimental medicine.

Low-temperature inhibition of antigen processing and iron uptake from transferrin: deficits in endosome functions at 18 degrees C.

E. Unanue, C. Harding, 1990, European journal of immunology.

Perspectives on anti-CD47 antibody treatment for experimental cancer

Emil R Unanue, E. Unanue, 2013, Proceedings of the National Academy of Sciences.

Batf3 Deficiency Reveals a Critical Role for CD8α+ Dendritic Cells in Cytotoxic T Cell Immunity

E. Unanue, M. Diamond, Whitney E. Purtha, 2008, Science.

The enhancement of a primary in vitro anti‐hapten response by carrier priming

E. Unanue, I. Trowbridge, H. J. Muller-Eberhard, 1972, European journal of immunology.

Dressing for the occasion: APCs make antigens presentable.

E. Unanue, J. McCluskey, 2008, Current opinion in immunology.

Antigen presentation in the autoimmune diabetes of the NOD mouse.

E. Unanue, 2014, Annual review of immunology.

RNA sensor-induced type I IFN prevents diabetes caused by a β cell-tropic virus in mice.

E. Unanue, M. Diamond, M. Colonna, 2011, The Journal of clinical investigation.

Fate and immunogenicity of antigens endocytosed by macrophages: a study using foreign red cells and immunoglobulin G.

E. Unanue, A. Cruchaud, 1971, Journal of immunology.

LIGAND-INDUCED MOVEMENT OF LYMPHOCYTE SURFACE MACROMOLECULES

E. Unanue, M. Karnovsky, K. Ault, 1974, The Journal of experimental medicine.

Antigen presentation events in autoimmune diabetes.

E. Unanue, B. Calderon, 2012, Current opinion in immunology.

Enhanced immunogenicity of a T cell immunogenic peptide by modifications of its N and C termini.

E. Unanue, P. Allen, J. Freeman, 1989, International immunology.

Antigen Recognition by Lymphocytes

E. Unanue, 1977 .

Cellular events folowing binding of antigen to lymphocytes.

E. Unanue, 1974, The American journal of pathology.

EVENTS AFTER THE BINDING OF ANTIGEN TO LYMPHOCYTES

E. Unanue, K. Ault, Emil R. Unanue, 1974, The Journal of experimental medicine.

SECRETION BY MACROPHAGES OF TWO MOLECULES MODULATING CELL PROLIFERATION

E. Unanue, J. Calderón, J. Kiely, 1975 .

Macrophage-antigen interaction: uptake, metabolism and immunogenicity of foreign albumin.

E. Unanue, J. Schmidtke, 1971, Journal of immunology.

As the main source of lymphocytes with detectable surface-bound immunoglobulin.

E. Unanue, P. Campbell, E. Rabellino, 1971 .

Antigen-binding thymic lymphocytes: specific binding of soluble antigen molecules and quantitation of surface receptor sites.

E. Unanue, H. Engers, 1974, Journal of immunology.

A minor subset of Batf3-dependent antigen-presenting cells in islets of Langerhans is essential for the development of autoimmune diabetes.

E. Unanue, K. Murphy, Javier A. Carrero, 2014, Immunity.

Brief Definitive Report Spontaneous Redistribution of Surface Immunoglobulin in the Motile B Lymphocyte* Materials and Methods the Journal of Experimental Medicine @bullet Volume

E. Unanue, J. Braun, G. Schreiner, 2003 .

The requirement for esterase activation in the anti-immunoglobulin-triggered movement of B lymphocytes.

E. Unanue, E. Becker, 1976, Journal of immunology.

ANTIGEN BINDING AND CAPPING BY LYMPHOCYTES OF GENETIC NONRESPONDER MICE

E. Unanue, B. Benacerraf, E. Dunham, 1972, The Journal of experimental medicine.

CYTOLOGICAL ANALYSIS OF HISTOCOMPATIBILITY MOLECULES

E. Unanue, 1976 .

Immunologic Events in Experimental Hypersensitivity Granulom~as

E. Unanue, B. Benacerraf, 2007 .

Publisher Correction: The MHC-II peptidome of pancreatic islets identifies key features of autoimmune peptides

Cheryl F. Lichti, E. Unanue, A. Chervonsky, 2020, Nature Immunology.

A novel pathway of presentation by class II-MHC molecules involving peptides or denatured proteins important in autoimmunity.

E. Unanue, James F. Mohan, 2013, Molecular immunology.

Opinions

E. Unanue, G. Schreiner, 1977, The Journal of Immunology.

Altered Peptide Ligands Make Their Entry

E. Unanue, 2011, The Journal of Immunology.

Response to Comment on Suri et al. on Diabetes Reversal in NOD Mice

E. Unanue, A. Suri, 2006, Science.