U. Baxa

发表

Crystal structure of phage P22 tailspike protein complexed with Salmonella sp. O-antigen receptors.

S. Steinbacher, U. Baxa, S. Miller, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Vaccine-Induced Antibodies that Neutralize Group 1 and Group 2 Influenza A Viruses

Cinque S. Soto, U. Baxa, J. Mullikin, 2016, Cell.

Structure-Based Design of a Fusion Glycoprotein Vaccine for Respiratory Syncytial Virus

Cinque S. Soto, U. Baxa, G. Chuang, 2013, Science.

Crystal structure , conformational fixation , and entry-related interactions of mature ligand-free HIV-1 Env

Young Do Kwon, Tongqing Zhou, Baoshan Zhang, 2016 .

Niemann–Pick Disease Type C

U. Baxa, C. Austin, Wei Zheng, 2014, Journal of biomolecular screening.

Trimeric HIV-1-Env Structures Define Glycan Shields from Clades A, B, and G

Young Do Kwon, Tongqing Zhou, Baoshan Zhang, 2016, Cell.

The Tailspike Protein of Shigella Phage Sf6

Ulrich Baxa, U. Baxa, R. Seckler, 2003, The Journal of Biological Chemistry.

A Neutralizing Antibody Recognizing Primarily N‐Linked Glycan Targets the Silent Face of the HIV Envelope

U. Baxa, J. Mullikin, J. Mascola, 2018, Immunity.

Conformational switching in PolyGln amyloid fibrils resulting from a single amino acid insertion.

U. Baxa, O. Antzutkin, A. Steven, 2014, Biophysical journal.

Induced Pluripotent Stem Cells for Disease Modeling and Evaluation of Therapeutics for Niemann-Pick Disease Type A

U. Baxa, Wei Zheng, J. Marugan, 2016, Stem cells translational medicine.

Architecture of Ure2p Prion Filaments

U. Baxa, R. Wickner, A. Steven, 2003, Journal of Biological Chemistry.

Structural basis for early-onset neurological disorders caused by mutations in human selenocysteine synthase

U. Baxa, S. Subramaniam, D. Matthies, 2016, Scientific Reports.

Morphological development of cellulose fibrils of a bleached eucalyptus pulp by mechanical fibrillation

U. Baxa, Qianqian Wang, J. Y. Zhu, 2012, Cellulose.

Amyloid structure and assembly: insights from scanning transmission electron microscopy.

U. Baxa, A. Engel, A. Steven, 2011, Journal of structural biology.

Mito-Tempol and Dexrazoxane Exhibit Cardioprotective and Chemotherapeutic Effects through Specific Protein Oxidation and Autophagy in a Syngeneic Breast Tumor Preclinical Model

U. Baxa, S. Pizzo, B. Aryal, 2013, PloS one.

Structural and molecular basis for Ebola virus neutralization by protective human antibodies

U. Baxa, N. Sullivan, A. Lanzavecchia, 2016, Science.

The N-terminal prion domain of Ure2p converts from an unfolded to a thermally resistant conformation upon filament formation.

U. Baxa, R. Wickner, A. Steven, 2004, Journal of molecular biology.

Platelet-derived growth factor-α receptor is the cellular receptor for human cytomegalovirus gHgLgO trimer

U. Baxa, R. Geiger, F. Sallusto, 2016, Nature Microbiology.

A ketogenic diet increases brown adipose tissue mitochondrial proteins and UCP1 levels in mice

U. Baxa, Xiaoyuan Chen, G. Niu, 2013, IUBMB life.

Mitochondrial biogenesis and increased uncoupling protein 1 in brown adipose tissue of mice fed a ketone ester diet

U. Baxa, K. Clarke, Xiaoyuan Chen, 2012, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Structure of RSV Fusion Glycoprotein Trimer Bound to a Prefusion-Specific Neutralizing Antibody

U. Baxa, T. Zhou, P. Kwong, 2013, Science.

Erratum: Early steps in primary cilium assembly require EHD1/EHD3-dependent ciliary vesicle formation

U. Baxa, J. Lippincott-Schwartz, S. Caplan, 2015, Nature Cell Biology.

Parvovirus B19 does not bind to membrane-associated globoside in vitro.

U. Baxa, R. Seckler, M. Rossmann, 2005, Virology.

Structural basis of infectious and non-infectious amyloids.

U. Baxa, 2008, Current Alzheimer research.

Prion and non-prion amyloids of the HET-s prion forming domain.

U. Baxa, A. Steven, M. Maddelein, 2007, Journal of molecular biology.

Imaging of Polyethylene Glycol Layers on Nanoparticles

U. Baxa, Mackensie C. Smith, A. Patri, 2015, Microscopy and Microanalysis.

Approaching zero cellulose loss in cellulose nanocrystal (CNC) production: recovery and characterization of cellulosic solid residues (CSR) and CNC

U. Baxa, Qianqian Wang, R. Reiner, 2012, Cellulose.

Prions beget prions: the [PIN+] mystery!

U. Baxa, B. Roberts, R. Wickner, 2001, Trends in biochemical sciences.

Mass Analysis by Scanning Transmission Electron Microscopy and Electron Diffraction Validate Predictions of Stacked β-Solenoid Model of HET-s Prion Fibrils*

U. Baxa, A. Steven, J. Wall, 2007, Journal of Biological Chemistry.

Iterative structure-based improvement of a respiratory syncytial virus fusion glycoprotein vaccine

Cinque S. Soto, U. Baxa, J. Mascola, 2016 .

Design of a Multicompartment Hydrogel that Facilitates Time-Resolved Delivery of Combination Therapy and Synergized Killing of Glioblastoma.

U. Baxa, S. Walsh, J. Schneider, 2018, Angewandte Chemie.

A model for Ure2p prion filaments and other amyloids: the parallel superpleated beta-structure.

Andrey V Kajava, Alasdair C Steven, Ulrich Baxa, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Immunoelectron Microscopy for Visualization of Nanoparticles.

K. Nagashima, U. Baxa, Sarah R. Anderson, 2018, Methods in molecular biology.

Protection of calves by a prefusion-stabilized bovine RSV F vaccine

U. Baxa, J. Mascola, Y. Lai, 2017, npj Vaccines.

Enzymatic preparation of nanocrystalline and microcrystalline cellulose

U. Baxa, D. Esposito, S. McNeil, 2014 .

Characterization challenges for a cellulose nanocrystal reference material: dispersion and particle size distributions

Jeffrey D. Clogston, Ulrich Baxa, Wadood Y. Hamad, 2018, Journal of Nanoparticle Research.

A virus-like particle vaccine prevents equine encephalitis virus infection in nonhuman primates

U. Baxa, J. Mascola, S. Higgs, 2019, Science Translational Medicine.

In Sup35p filaments (the [PSI+] prion), the globular C‐terminal domains are widely offset from the amyloid fibril backbone

U. Baxa, A. Steven, J. Wall, 2011, Molecular microbiology.

Prions of yeast as epigenetic phenomena: high protein "copy number" inducing protein "silencing".

U. Baxa, B. Roberts, R. Wickner, 2002, Advances in genetics.

Phage P22 tailspike protein: crystal structure of the head-binding domain at 2.3 Å, fully refined structure of the endorhamnosidase at 1.56 Å resolution, and the molecular basis of O-antigen recognition and cleavage1

S. Steinbacher, U. Baxa, A. Weintraub, 1997, Journal of Molecular Biology.

Interactions of phage P22 tails with their cellular receptor, Salmonella O-antigen polysaccharide.

S. Steinbacher, U. Baxa, S. Miller, 1996, Biophysical Journal.

Rational Design of an Epstein-Barr Virus Vaccine Targeting the Receptor-Binding Site

U. Baxa, J. Mascola, M. Rossmann, 2015, Cell.

A Frizzled‐Like Cysteine‐Rich Domain in Glypican‐3 Mediates Wnt Binding and Regulates Hepatocellular Carcinoma Tumor Growth in Mice

U. Baxa, Mitchell Ho, Hongjun Bai, 2019, Hepatology.

δ-Tocopherol Reduces Lipid Accumulation in Niemann-Pick Type C1 and Wolman Cholesterol Storage Disorders*

Christopher P Austin, Noel Southall, Wei Sun, 2012, The Journal of Biological Chemistry.

Characterization of β-sheet structure in Ure2p1- 89 yeast prion fibrils by solid-state nuclear magnetic resonance

U. Baxa, D. E. Anderson, R. Tycko, 2007 .

Characterization of beta-sheet structure in Ure2p1-89 yeast prion fibrils by solid-state nuclear magnetic resonance.

U. Baxa, D. E. Anderson, R. Tycko, 2007, Biochemistry.

Prions of yeast are genes made of protein: amyloids and enzymes.

U. Baxa, R. Wickner, F. Shewmaker, 2004, Cold Spring Harbor symposia on quantitative biology.

β arcades: recurring motifs in naturally occurring and disease‐related amyloid fibrils

Ulrich Baxa, U. Baxa, A. Steven, 2010, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Fibril Structure of Human Islet Amyloid Polypeptide*♦

Ian S. Haworth, Ralf Langen, Ulrich Baxa, 2011, The Journal of Biological Chemistry.

Structure-based design of a quadrivalent fusion glycoprotein vaccine for human parainfluenza virus types 1–4

M. Beltramello, U. Baxa, J. Mascola, 2018, Proceedings of the National Academy of Sciences.

The crystal structure of human GlnRS provides basis for the development of neurological disorders

U. Baxa, S. Subramaniam, D. Matthies, 2016, Nucleic acids research.

The GB1 amyloid fibril: recruitment of the peripheral beta-strands of the domain swapped dimer into the polymeric interface.

U. Baxa, A. Gronenborn, J. Louis, 2005, Journal of molecular biology.

Orthogonal inactivation of influenza and the creation of detergent resistant viral aggregates: towards a novel vaccine strategy

U. Baxa, R. Blumenthal, Mathias Viard, 2012, Virology Journal.

Structure, function, and amyloidogenesis of fungal prions: filament polymorphism and prion variants.

Andrey V Kajava, Alasdair C Steven, Ulrich Baxa, 2006, Advances in protein chemistry.

Prions: proteins as genes and infectious entities.

U. Baxa, B. Roberts, R. Wickner, 2004, Genes & development.

Mechanism of inactivation on prion conversion of the Saccharomyces cerevisiae Ure2 protein

Alasdair C Steven, Ulrich Baxa, U. Baxa, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Prion generation in vitro: amyloid of Ure2p is infectious

U. Baxa, R. Wickner, A. Brachmann, 2005, The EMBO journal.

Structures of HIV-1-Env V1V2 with broadly neutralizing antibodies reveal commonalities that enable vaccine design

Jonathan R. McDaniel, Cinque S. Soto, U. Baxa, 2015, Nature Structural &Molecular Biology.

Mosaic nanoparticle display of diverse influenza virus hemagglutinins elicits broad B cell responses

U. Baxa, J. Mascola, R. Koup, 2018, Nature Immunology.

Early steps in primary cilium assembly require EHD1- and EHD3-dependent ciliary vesicle formation

U. Baxa, J. Lippincott-Schwartz, S. Caplan, 2015, Nature Cell Biology.

Filaments of the Ure2p prion protein have a cross-β core structure

Dennis C Winkler, U. Baxa, D. Davies, 2005 .

Filaments of the Ure2p prion protein have a cross-beta core structure.

Dennis C Winkler, U. Baxa, D. Davies, 2005, Journal of structural biology.

Interaction of Salmonella Phage P22 with Its O-Antigen Receptor Studied by X-Ray Crystallography

S. Steinbacher, U. Baxa, A. Weintraub, 1997, Biological chemistry.

Iterative structure-based improvement of a respiratory syncytial virus fusion glycoprotein vaccine

Cinque S. Soto, U. Baxa, J. Mascola, 2016, Nature Structural &Molecular Biology.

A Cysteine Zipper Stabilizes a Pre-Fusion F Glycoprotein Vaccine for Respiratory Syncytial Virus

Cinque S. Soto, U. Baxa, J. Mascola, 2015, PloS one.

Single-Chain Soluble BG505.SOSIP gp140 Trimers as Structural and Antigenic Mimics of Mature Closed HIV-1 Env

U. Baxa, J. Mascola, G. Chuang, 2015, Journal of Virology.

Scrambled Prion Domains Form Prions and Amyloid

Eric D. Ross, Ulrich Baxa, U. Baxa, 2004, Molecular and Cellular Biology.

PRION GENETICS: Ne wR ules for a New Kind of Gene 1

U. Baxa, R. Wickner, F. Shewmaker, 2004 .

Prion genetics: new rules for a new kind of gene.

U. Baxa, R. Wickner, F. Shewmaker, 2004, Annual review of genetics.

Is the prion domain of soluble Ure2p unstructured?

Ad Bax, Alasdair C Steven, Ulrich Baxa, 2005, Biochemistry.

Structural dependence of HET-s amyloid fibril infectivity assessed by cryoelectron microscopy

U. Baxa, A. Steven, N. Mizuno, 2011, Proceedings of the National Academy of Sciences.

Mosaic nanoparticle display of diverse influenza virus hemagglutinins elicits broad B cell responses

U. Baxa, J. Mascola, R. Koup, 2018, Nature Immunology.

Crystal Structure of a Virus-Encoded Putative Glycosyltransferase

U. Baxa, J. V. Van Etten, M. Rossmann, 2010, Journal of Virology.

Characterization of a Prefusion-Specific Antibody That Recognizes a Quaternary, Cleavage-Dependent Epitope on the RSV Fusion Glycoprotein

U. Baxa, B. Graham, Syed M. Moin, 2015, PLoS pathogens.

Detection of Phospholipidosis Induction

Ruili Huang, Christopher P Austin, Menghang Xia, 2014, Journal of biomolecular screening.

Carbohydrate binding of Salmonella phage P22 tailspike protein and its role during host cell infection.

U. Baxa, R. Seckler, Dorothee Andres, 2010, Biochemical Society transactions.

Biopolymer-connected liposome networks as injectable biomaterials capable of sustained local drug delivery.

U. Baxa, S. Raghavan, R. Blumenthal, 2012, Biomacromolecules.

Structural Basis for the Coordinated Regulation of Transglutaminase 3 by Guanine Nucleotides and Calcium/Magnesium*

U. Baxa, W. Idler, P. Steinert, 2004, Journal of Biological Chemistry.

Enthalpic barriers to the hydrophobic binding of oligosaccharides to phage P22 tailspike protein.

U. Baxa, A. Weintraub, R. Seckler, 2001, Biochemistry.

Tailspike Interactions with Lipopolysaccharide Effect DNA Ejection from Phage P22 Particles in Vitro*

U. Baxa, R. Seckler, Dorothee Andres, 2010, The Journal of Biological Chemistry.

Autophosphorylation-induced self-assembly and STIL-dependent reinforcement underlie Plk4’s ring-to-dot localization conversion around a human centriole

K. Nagashima, U. Baxa, Kyung S. Lee, 2020, Cell Cycle.

Soluble Prefusion Closed DS-SOSIP.664-Env Trimers of Diverse HIV-1 Strains.

U. Baxa, J. Mascola, G. Chuang, 2017, Cell reports.

Hyperthermia-triggered intracellular delivery of anticancer agent to HER2(+) cells by HER2-specific affibody (ZHER2-GS-Cys)-conjugated thermosensitive liposomes (HER2(+) affisomes).

U. Baxa, I. Lyakhov, R. Blumenthal, 2011, Journal of controlled release : official journal of the Controlled Release Society.

Two-Component Ferritin Nanoparticles for Multimerization of Diverse Trimeric Antigens.

U. Baxa, J. Mascola, I. Georgiev, 2018, ACS infectious diseases.

ArfGAP1 promotes COPI vesicle formation by facilitating coatomer polymerization

K. Nagashima, U. Baxa, E. Sztul, 2011, Cellular logistics.

Orthogonal inactivation of influenza and the creation of detergent resistant viral aggregates: towards a novel vaccine strategy

U. Baxa, R. Blumenthal, Mathias Viard, 2012, Virology Journal.

Roles of Calcium Ions in the Activation and Activity of the Transglutaminase 3 Enzyme*

Ulrich Baxa, U. Baxa, W. Idler, 2003, Journal of Biological Chemistry.

Mutations improving the folding of phage P22 tailspike protein affect its receptor binding activity.

S. Steinbacher, U. Baxa, A. Weintraub, 1999, Journal of molecular biology.

Imaging of Liposomes by Transmission Electron Microscopy.

U. Baxa, 2018, Methods in molecular biology.

A Conserved Mechanism for Centromeric Nucleosome Recognition by Centromere Protein CENP-C

U. Baxa, A. Straight, R. Ghirlando, 2013, Science.

Crystal structure, conformational fixation, and entry-related interactions of mature ligand-free HIV-1 Env

James B. Munro, Daniel S. Terry, Cinque S. Soto, 2015, Nature Structural &Molecular Biology.

Degradation of fungal prion HET-s(218-289) induces formation of a generic amyloid fold.

U. Baxa, S. Prusiner, G. Stubbs, 2012, Biophysical journal.

δ-Tocopherol Reduces Lipid Accumulation in Niemann-Pick Type C1 and Wolman Cholesterol Storage Disorders*

U. Baxa, W. Pavan, Noel Southall, 2012, Journal of Biological Chemistry.