P. Reinemer

发表

Crystal structure of P22 tailspike protein: interdigitated subunits in a thermostable trimer.

S. Steinbacher, S. Miller, R. Seckler, 1994, Science.

Discovery of the novel antithrombotic agent 5-chloro-N-({(5S)-2-oxo-3- [4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)thiophene- 2-carboxamide (BAY 59-7939): an oral, direct factor Xa inhibitor.

Thomas Lampe, Elisabeth Perzborn, P. Reinemer, 2005, Journal of medicinal chemistry.

MPSA short communications

W. E. Moddeman, J. A. Lindquist, D. N. Perkins, 1988 .

Structure determination and refinement of human alpha class glutathione transferase A1-1, and a comparison with the Mu and Pi class enzymes.

G J Kleywegt, G L Gilliland, R. Huber, 1993, Journal of molecular biology.

Herbicide detoxification by glutathione S-transferases as implicated from X-ray structures†

R. Huber, P. Reinemer, L. Prade, 1999 .

Recognition of the tripeptide glutathione by cytosolic glutathione S-transferases: An X-ray crystallographic analysis

R. Huber, P. Reinemer, H. Dirr, 1994 .

Crystal structure of full length topoisomerase I from Thermotoga maritima.

P. Reinemer, D. Schomburg, G. Hansen, 2006, Journal of molecular biology.

Refined crystal structure of porcine class Pi glutathione S-transferase (pGST P1-1) at 2.1 A resolution.

R. Huber, P. Reinemer, H. Dirr, 1994, Journal of molecular biology.

Mutational substitution of residues implicated by crystal structure in binding the substrate glutathione to human glutathione S-transferase pi.

R. Huber, P. Reinemer, W. E. Fahl, 1992, Journal of molecular biology.

Unusual reactivity of Tyr-7 of GSH transferase P1-1.

R. Huber, P. Reinemer, B. Ketterer, 1993, The Biochemical journal.

Chemical modification of GSH transferase P1-1 confirms the presence of Arg-13, Lys-44 and one carboxylate group in the GSH-binding domain of the active site.

R. Huber, P. Reinemer, B. Ketterer, 1993, The Biochemical journal.

Crystals of a 1:1 complex between human interleukin-4 and the extracellular domain of its receptor alpha chain.

P. Reinemer, T. Hage, W. Sebald, 1998, European journal of biochemistry.

S-transferase incomplexwithglutathione sulfonate at 2.3A resolution

P. Reinemer, R. Ladenstein, O. Gallay, 2005 .

Equilibrium unfolding of class pi glutathione S-transferase.

P. Reinemer, H. Dirr, 1991, Biochemical and biophysical research communications.

Cinnabaramides A-G: analogues of lactacystin and salinosporamide from a terrestrial streptomycete.

P. Reinemer, Anke Mayer-Bartschmid, M. Stadler, 2007, Journal of natural products.

Development of a simple homogeneous assay to screen for inhibitors of N-acetylglucosamine-6-sulfotransferases.

P. Reinemer, A. Yamato, H. Togame, 2003, Analytical biochemistry.

A Versatile High-Throughput Screen for Inhibitors of Lipid Kinase Activity: Development of an Immobilized Phospholipid Plate Assay for Phosphoinositide 3-Kinase γ

P. Reinemer, F. Gantner, K. Bacon, 2002, Journal of biomolecular screening.

The metzincins — Topological and sequential relations between the astacins, adamalysins, serralysins, and matrixins (collagenases) define a super family of zinc‐peptidases

P. Reinemer, U. Baumann, W. Bode, 1995, Protein science : a publication of the Protein Society.

Crystal structure of the catalytic subunit of human protein phosphatase 1 and its complex with tungstate.

P. Reinemer, D. Barford, P. Cohen, 1995, Journal of molecular biology.

CRYSTAL AND MOLECULAR STRUCTURE OF 1-AMINO-BENZYLPHOSPHONOUS ACID MONOHYDRATE

P. Reinemer, G. Hägele, D. Mootz, 1992 .

X-ray crystal structures of cytosolic glutathione S-transferases. Implications for protein architecture, substrate recognition and catalytic function.

R. Huber, P. Reinemer, H. Dirr, 1994, European journal of biochemistry.

Macrocyclic Statine‐Based Inhibitors of BACE‐1

P. Reinemer, C. Renner, W. Bode, 2007, Chembiochem : a European journal of chemical biology.

Three-dimensional structure of glutathione S-transferase from Arabidopsis thaliana at 2.2 A resolution: structural characterization of herbicide-conjugating plant glutathione S-transferases and a novel active site architecture.

R. Huber, P. Reinemer, K. Palme, 1996, Journal of molecular biology.

The three‐dimensional structure of class pi glutathione S‐transferase in complex with glutathione sulfonate at 2.3 A resolution.

R. Huber, P. Reinemer, R. Ladenstein, 1991, The EMBO journal.

Electrostatic evidence for the activation of the glutathione thiol by Tyr7 in pi-class glutathione transferases.

R. Huber, P. Reinemer, A. Karshikoff, 1993, European journal of biochemistry.

Unexpected active-site flexibility in the structure of human neutrophil elastase in complex with a new dihydropyrimidone inhibitor.

Dietmar Schomburg, P. Reinemer, D. Schomburg, 2011, Journal of molecular biology.

Three-dimensional structure of class pi glutathione S-transferase from human placenta in complex with S-hexylglutathione at 2.8 A resolution.

M W Parker, R. Huber, P. Reinemer, 1992, Journal of molecular biology.

The metzincin-superfamily of zinc-peptidases.

P. Reinemer, U. Baumann, W. Bode, 1996, Advances in experimental medicine and biology.

[22] X-ray structure methods for glutathione binding

R. Huber, P. Reinemer, H. Dirr, 1995 .

Crystal Structure of the Interleukin-4/Receptor α Chain Complex Reveals a Mosaic Binding Interface

P. Reinemer, T. Hage, W. Sebald, 1999, Cell.

Kinetic and structural insights into the binding of histone deacetylase 1 and 2 (HDAC1, 2) inhibitors.

S. Steinbacher, P. Reinemer, S. Haggarty, 2016, Bioorganic & medicinal chemistry.

X-ray structures of human neutrophil collagenase complexed with peptide hydroxamate and peptide thiol inhibitors. Implications for substrate binding and rational drug design.

R. Huber, P. Reinemer, W. Bode, 1995, European journal of biochemistry.

X‐ray Structures of Human Neutrophil Collagenase Complexed with Peptide Hydroxamate and Peptide Thiol Inhibitors

R. Huber, P. Reinemer, W. Bode, 1995 .

Targeted proteomics in biomarker validation: Detection and quantification of proteins using a multi‐dimensional peptide separation strategy

P. Reinemer, D. Immler, Simone Greven, 2006, Proteomics.

Cloning, sequencing, crystallization and X-ray structure of glutathione S-transferase-III from Zea mays var. mutin: a leading enzyme in detoxification of maize herbicides.

R. Huber, P. Reinemer, L. Prade, 1997, Journal of molecular biology.

Plant glutathione S-transferases and herbicide detoxification.

P. Reinemer, T. Neuefeind, B. Bieseler, 1997, Biological chemistry.

The X‐ray crystal structure of the catalytic domain of human neutrophil collagenase inhibited by a substrate analogue reveals the essentials for catalysis and specificity.

R. Huber, P. Reinemer, W. Bode, 1994, The EMBO journal.

Inhibition of Matrix Metalloproteinases in Rheumatoid Arthritis and the Crystallographic Binding Mode of a Peptide Inhibitor

P. Reinemer, W. Bode, H. Tschesche, 1994, Annals of the New York Academy of Sciences.

Structural implications for the role of the N terminus in the ‘superactivation’ of collagenases

R. Huber, P. Reinemer, W. Bode, 1994, FEBS letters.

Function and Structure of Human Leucocyte Collagenase

P. Reinemer, W. Bode, H. Tschesche, 1995 .

Development of a simple and robust assay to screen for inhibitors of sphingosine kinases.

P. Reinemer, T. Inaoka, H. Togame, 2007, Assay and drug development technologies.

Class π glutathione S-transferase from pig lung

R. Huber, P. Reinemer, R. Ladenstein, 1991 .

INTERLEUKIN-4 / RECEPTOR ALPHA CHAIN COMPLEX

P. Reinemer, T. Hage, W. Sebald, 2000 .

Alkylation of rabbit muscle creatine kinase surface methionine residues inhibits enzyme activity in vitro

P. Reinemer, T. Gudermann, M. Siegert, 2021, Archives of Toxicology.

Structure determination and refinement of human alpha class glutathione transferase A1-1, and a comparison with the Mu and Pi class enzymes.

P. Reinemer, G. Kleywegt, G. Gilliland, 1993, Journal of molecular biology.