Z. Paroush

发表

Substrate-dependent control of MAPK phosphorylation in vivo

Yoosik Kim, Z. Paroush, K. Nairz, 2011, Molecular systems biology.

Groucho acts as a corepressor for a subset of negative regulators, including Hairy and Engrailed.

Z. Paroush, G. Jiménez, D. Ish-Horowicz, 1997, Genes & development.

MAPK Substrate Competition Integrates Patterning Signals in the Drosophila Embryo

Yoosik Kim, Z. Paroush, G. Jiménez, 2010, Current Biology.

Ras–Erk signaling induces phosphorylation of human TLE1 and downregulates its repressor function

Z. Paroush, E. Shaulian, R. Karni, 2017, Oncogene.

Transcriptional repression by AML1 and LEF-1 is mediated by the TLE/Groucho corepressors.

Z. Paroush, S. Stifani, Y. Bernstein, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Dynamics of demethylation and activation of the α-actin gene in myoblasts

Z. Paroush, H. Cedar, J. Yisraeli, 1990, Cell.

Novel interplay between JNK and Egfr signaling in Drosophila dorsal closure

Z. Paroush, T. Kushnir, R. Lange, 2017, PLoS genetics.

Demethylation of genes in animal cells.

Z. Paroush, A. Razin, H. Cedar, 1990, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.

Transcriptional repression by AML 1 and LEF-1 is mediated by the TLE y Groucho corepressors

Z. Paroush, S. Stifani, Hua Tang, 1998 .

Phosphorylation of Groucho Mediates RTK Feedback Inhibition and Prolonged Pathway Target Gene Expression

Z. Paroush, G. Jiménez, A. Orian, 2011, Current Biology.

Detection of RTK pathway activation in Drosophila using anti-dpERK immunofluorescence staining.

Z. Paroush, A. Helman, 2010, Methods in molecular biology.

Dynamics of demethylation and activation of the alpha-actin gene in myoblasts.

Z. Paroush, H. Cedar, I. Keshet, 1990, Cell.

EGFR signaling attenuates Groucho-dependent repression to antagonize Notch transcriptional output

Z. Paroush, S. Jia, A. Courey, 2005, Nature Genetics.

Groucho augments the repression of multiple Even skipped target genes in establishing parasegment boundaries.

Z. Paroush, M. Fujioka, J. B. Jaynes, 2001, Development.

Groucho Oligomerization Is Required for Repression In Vivo

Z. Paroush, A. Courey, Haiyun Song, 2004, Molecular and Cellular Biology.

Context-dependent regulation of Groucho/TLE-mediated repression.

Z. Paroush, Einat Cinnamon, 2008, Current opinion in genetics & development.

Origins of Context-Dependent Gene Repression by Capicua

Z. Paroush, G. Jiménez, N. Samper, 2015, PLoS genetics.

The Capicua repressor – a general sensor of RTK signaling in development and disease

Z. Paroush, G. Jiménez, S. Shvartsman, 2012, Journal of Cell Science.

Capicua DNA-binding sites are general response elements for RTK signaling in Drosophila

Z. Paroush, G. Jiménez, A. Courey, 2011, Development.

Drosophila Spidey/Kar Regulates Oenocyte Growth via PI3-Kinase Signaling

Z. Paroush, A. Gould, G. J. Blomquist, 2016, PLoS genetics.

Capicua controls Toll/IL-1 signaling targets independently of RTK regulation

Z. Paroush, G. Jiménez, J. Zeitlinger, 2018, Proceedings of the National Academy of Sciences.

A MAPK docking site is critical for downregulation of Capicua by Torso and EGFR RTK signaling

Z. Paroush, G. Jiménez, R. Grossman, 2007, The EMBO journal.

Cell cycle progression requires repression by Groucho during S-phase and its relief at G2-phase

Z. Paroush, Shaked Bar-Cohen, 2022, bioRxiv.

RTK signaling modulates the Dorsal gradient

Yoosik Kim, Z. Paroush, G. Jiménez, 2012, Development.

Conversion of dorsal from an activator to a repressor by the global corepressor Groucho.

Z. Paroush, J. Lengyel, T. Dubnicoff, 1997, Genes & development.

Groucho is required for Drosophila neurogenesis, segmentation, and sex determination and interacts directly with hairy-related bHLH proteins

Roger Brent, Russell L. Finley, David Ish-Horowicz, 1994, Cell.

Drosophila CK2 phosphorylates Hairy and regulates its activity in vivo.

C. P. Bishop, Z. Paroush, R. Allada, 2008, Biochemical and biophysical research communications.

Huckebein repressor activity in Drosophila terminal patterning is mediated by Groucho.

Z. Paroush, G. Jiménez, O. Cook, 1999, Development.

Multiple RTK pathways downregulate Groucho-mediated repression in Drosophila embryogenesis

Z. Paroush, G. Jiménez, A. Orian, 2008, Development.

A Myc–Groucho complex integrates EGF and Notch signaling to regulate neural development

Z. Paroush, J. Delrow, R. Eisenman, 2007, Proceedings of the National Academy of Sciences.

Torso signalling regulates terminal patterning in Drosophila by antagonising Groucho-mediated repression.

Z. Paroush, D. Ish-Horowicz, S. Wainwright, 1997, Development.

Capicua integrates input from two maternal systems in Drosophila terminal patterning

Z. Paroush, G. Jiménez, D. St Johnston, 2004, The EMBO journal.

An Activating Mutation in ERK Causes Hyperplastic Tumors in a scribble Mutant Tissue in Drosophila

Z. Paroush, D. Engelberg, T. Kushnir, 2019, Genetics.

Drosophila melanogaster Casein Kinase II Interacts with and Phosphorylates the Basic Helix-Loop-Helix Proteins m5, m7, and m8 Derived from the Enhancer of split Complex*

Z. Paroush, M. Kalive, A. Bidwai, 2001, The Journal of Biological Chemistry.

Phosphorylation of the Drosophila melanogaster RNA–Binding Protein HOW by MAPK/ERK Enhances Its Dimerization and Activity

Z. Paroush, Ronit Nir, R. Grossman, 2012, PLoS genetics.

Results and discussion Removal of endogenous MAPK substrates reduces MAPK phosphorylation in vivo

Yoosik Kim, Z. Paroush, K. Nairz, 2013 .

Phosphorylation of Ind by MAP kinase enhances Ind-dependent transcriptional repression.

Z. Paroush, T. Von Ohlen, A. Helman, 2011, Developmental biology.

An eh1-Like Motif in Odd-skipped Mediates Recruitment of Groucho and Repression In Vivo

Z. Paroush, O. Cook, Umesh C. Karandikar, 2005, Molecular and Cellular Biology.

Phosphorylated Groucho delays differentiation in the follicle stem cell lineage by providing a molecular memory of EGFR signaling in the niche

Z. Paroush, Shaked Bar-Cohen, T. Nystul, 2016, Development.

Phospholipase C and termination of G-protein-mediated signalling in vivo

Z. Paroush, B. Minke, Boaz Cook, 2000, Nature Cell Biology.

Crosstalk between the EGFR and other signalling pathways at the level of the global transcriptional corepressor Groucho/TLE

Z. Paroush, P. Hasson, 2006, British Journal of Cancer.

Brinker requires two corepressors for maximal and versatile repression in Dpp signalling

Z. Paroush, K. Basler, B. Müller, 2001, The EMBO journal.

High-Throughput In Vitro Identification of Direct MAPK/Erk Substrates.

Z. Paroush, R. Grossman, 2017, Methods in molecular biology.

RTK signaling modulates the Dorsal gradient

Yoosik Kim, Z. Paroush, G. Jiménez, 2012, Development.

Multiple RTK pathways downregulate Groucho-mediated repression in Drosophila embryogenesis

Z. Paroush, G. Jiménez, A. Orian, 2008, Development.

Detection of RTK pathway activation in Drosophila using anti-dpERK immunofluorescence staining.

Z. Paroush, A. Helman, 2010, Methods in molecular biology.

WntD RTK signaling modulates the Dorsal

Z. Paroush, Bomyi Lim, Maria Jose Andreu, 2012 .

Crosstalk between the EGFR and other signalling pathways at the level of the global transcriptional corepressor Groucho/TLE.

Z. Paroush, P. Hasson, 2007, British Journal of Cancer.