J. Rothberg

发表

An integrated semiconductor device enabling non-optical genome sequencing

Bernard P. Puc, J. Rothberg, W. Hinz, 2011, Nature.

A comprehensive analysis of protein–protein interactions in Saccharomyces cerevisiae

James R. Knight, J. Rothberg, T. Kalbfleisch, 2000, Nature.

Genome sequencing in microfabricated high-density picolitre reactors

James R. Knight, J. W. Simpson, Bernard P. Puc, 2005, Nature.

The complete genome of an individual by massively parallel DNA sequencing

J. Lupski, G. Weinstock, J. Rothberg, 2008, Nature.

A Protein Interaction Map of Drosophila melanogaster

James R. Knight, J. Rothberg, J. Bader, 2003, Science.

Gaining confidence in high-throughput protein interaction networks

J. Rothberg, J. Bader, J. Chant, 2004, Nature Biotechnology.

Sensitive mutation detection in heterogeneous cancer specimens by massively parallel picoliter reactor sequencing

Thomas LaFramboise, Levi A Garraway, Kwok-Kin Wong, 2006, Nature Medicine.

Droplet microfluidic technology for single-cell high-throughput screening

N. Perrimon, J. Rothberg, D. Marran, 2009, Proceedings of the National Academy of Sciences.

A Complete Neandertal Mitochondrial Genome Sequence Determined by High-Throughput Sequencing

Philip L. F. Johnson, Adrian W. Briggs, Michael F. Siebauer, 2008, Cell.

Patterns of nucleotide misincorporations during enzymatic amplification and direct large-scale sequencing of ancient DNA

J. Rothberg, J. Simons, W. He, 2006, Proceedings of the National Academy of Sciences.

The development and impact of 454 sequencing

J. Rothberg, J. Leamon, 2008, Nature Biotechnology.

Analysis of one million base pairs of Neanderthal DNA

Adrian W. Briggs, J. Rothberg, J. Simons, 2006, Nature.

Genome Sequencing in Open Microfabricated High Density Picoliter Reactors

Yong Wang, Wen He, Joel S. Bader, 2005 .

DNA transport by a micromachined Brownian ratchet device.

J. W. Simpson, J. Rothberg, J. Bustillo, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Overview: methods and applications for droplet compartmentalization of biology

J. Rothberg, J. Leamon, M. Egholm, 2006, Nature Methods.

HIGH-THROUGHPUT, MASSIVELY PARALLEL DNA SEQUENCING TECHNOLOGY FOR THE ERA OF PERSONALIZED MEDICINE

J. Rothberg, J. Leamon, Michael S. Braverman, 2007 .

Impaired Mitochondrial Dynamics and Mitophagy in Neuronal Models of Tuberous Sclerosis Complex.

J. Rothberg, F. Polleux, Tommy L. Lewis, 2016, Cell reports.

The characterization of PPARα ligand drug action in an in vivo model by comprehensive differential gene expression profiling

J. Rothberg, S. Sundseth, D. Winegar, 2001, Functional & Integrative Genomics.

Assessment of Brain Injury Using Portable, Low-Field Magnetic Resonance Imaging at the Bedside of Critically Ill Patients.

Jennifer A. Kim, Matthew M. Yuen, J. Rothberg, 2020, JAMA neurology.

Low-Abundance Drug-Resistant Viral Variants in Chronically HIV-Infected, Antiretroviral Treatment– Naive Patients Signiﬁcantly Impact Treatment Outcomes Low-Abundance Viral in Chronically HIV (cid:3) Patients

J. Rothberg, J. Simons, M. Egholm, 2009 .

The characterization of PPAR alpha ligand drug action in an in vivo model by comprehensive differential gene expression profiling.

J. Rothberg, S. Sundseth, D. Winegar, 2001, Functional & integrative genomics.

Portable, bedside, low-field magnetic resonance imaging for evaluation of intracerebral hemorrhage

Jennifer A. Kim, Matthew M. Yuen, J. Rothberg, 2021, Nature Communications.

Low-abundance drug-resistant viral variants in chronically HIV-infected, antiretroviral treatment-naive patients significantly impact treatment outcomes.

Gregory S Turenchalk, Birgitte B Simen, J. Rothberg, 2009, The Journal of infectious diseases.

PDGF-D, a new protease-activated growth factor

J. Rothberg, Meijia Yang, R. Shimkets, 2001, Nature Cell Biology.

slit: an extracellular protein necessary for development of midline glia and commissural axon pathways contains both EGF and LRR domains.

J. Rothberg, C. Goodman, S. Artavanis-Tsakonas, 1990, Genes & development.

Erratum: Sensitive mutation detection in heterogeneous cancer specimens by massively parallel picoliter reactor sequencing

J. Rothberg, J. Leamon, J. Simons, 2006, Nature Medicine.

slit: An EGF-homologous locus of D. melanogaster involved in the development of the embryonic central nervous system

J. Rothberg, S. Artavanis-Tsakonas, Spyros Artavanis-Tsakonas, 1988, Cell.

Map of the Laboratory Rat A High-Density Integrated Genetic Linkage and Radiation Hybrid

E. Lander, J. Rothberg, T. Matise, 1999 .

Assessment of whole genome amplification-induced bias through high-throughput, massively parallel whole genome sequencing

Mark B Gerstein, Robert Pinard, M. Gerstein, 2006, BMC Genomics.

Massively parallel ("next-generation") DNA sequencing.

J. Rothberg, B. G. Gould Rothberg, 2015, Clinical chemistry.

LAM-003, a Novel Oral Heat Shock Protein 90 Inhibitor for Treatment of Acute Myeloid Leukemia, Including Wild-Type and FMS-like Tyrosine Kinase 3 (FLT3)-Mutant Disease

J. Rothberg, Tian Xu, S. Halene, 2019, Blood.

Detection of oncogenic mutations in the EGFR gene in lung adenocarcinoma with differential sensitivity to EGFR tyrosine kinase inhibitors.

J. Rothberg, J. Simons, M. Meyerson, 2005, Cold Spring Harbor symposia on quantitative biology.

Prospective Genomic Characterization of the German Enterohemorrhagic Escherichia coli O104:H4 Outbreak by Rapid Next Generation Sequencing Technology

J. Rothberg, Yongmei Ji, P. Brzoska, 2011, PloS one.

Real-time dynamic single-molecule protein sequencing on an integrated semiconductor device

Matthew D. Dyer, Antoine M. van Oijen, J. Rothberg, 2022, bioRxiv.

Corrigendum: Genome sequencing in microfabricated high-density picolitre reactors

Yong Wang, Eugene W. Myers, Joel S. Bader, 2006, Nature.

DNA Sequencing and Genomics

J. Rothberg, J. Leamon, 2009 .

Progress in Ion Torrent semiconductor chip based sequencing

Barry Merriman, Ion Torrent R&D Team, Jonathan M. Rothberg, 2012, Electrophoresis.

Identification of apilimod as a first-in-class PIKfyve kinase inhibitor for treatment of B-cell non-Hodgkin lymphoma.

Paul Beckett, Jonathan Rothberg, J. Rothberg, 2017, Blood.

Modularity of the slit protein. Characterization of a conserved carboxy-terminal sequence in secreted proteins and a motif implicated in extracellular protein interactions.

J. Rothberg, S. Artavanis-Tsakonas, 1992, Journal of molecular biology.

LAM-003, a new drug for treatment of tyrosine kinase inhibitor-resistant FLT3-ITD-positive AML.

J. Rothberg, M. Andreeff, Tian Xu, 2019, Blood advances.

Simulation of neural nets with some applications to visual information processing.

J M Rothberg, J. Rothberg, 1968, Computers and biomedical research, an international journal.

Impaired Mitochondrial Dynamics And Mitophagy In Neuronal Models Of Tuberous Sclerosis Complex.

J. Rothberg, F. Polleux, Tommy L. Lewis, 2016, Cell reports.

New Paradigms in Droplet‐Based Microfluidics and DNA Amplification

J. Rothberg, J. Leamon, D. Mead, 2009 .

Cramming More Sequencing Reactions onto Microreactor Chips

J. Rothberg, J. Leamon, 2007 .

Identi fi cation of apilimod as a fi rst-in-class PIKfyve kinase inhibitor for treatment of B-cell non-Hodgkin lymphoma

J. Rothberg, Tian Xu, Meiling Zheng, 2017 .

Differential transport of DNA by a rectified Brownian motion device

J. Rothberg, J. Bustillo, J. Bader, 2000, Electrophoresis.

Gene expression analysis by transcript profiling coupled to a gene database query

J. W. Simpson, Andreas Windemuth, J. Rothberg, 1999, Nature Biotechnology.

A Brownian-ratchet DNA pump with applications to single-nucleotide polymorphism genotyping

Michael W. Deem, Joel S. Bader, Steven A. Henck, 2002 .

Point-of-Care MRI with Artificial Intelligence to Measure Midline Shift in Acute Stroke Follow-Up

Seyed Sadegh Mohseni Salehi, Matthew M. Yuen, J. Rothberg, 2022, medRxiv.

The Chediak-Higashi Protein Interacts with SNARE Complex and Signal Transduction Proteins

J. Rothberg, S. Kingsmore, K. Nandabalan, 2002, Molecular medicine.

Radiation resistance of sequencing chips for in situ life detection.

Gary Ruvkun, Christopher E Carr, Holli Rowedder, 2013, Astrobiology.

A transmission imaging spectrograph and microfabricated channel system for DNA analysis

J. W. Simpson, J. Rothberg, J. Berka, 2000, Electrophoresis.

Ultrasound-on-chip platform for medical imaging, analysis, and collective intelligence

J. R. Petrus, J. Rothberg, K. Thiele, 2021, Proceedings of the National Academy of Sciences.

A high-density integrated genetic linkage and radiation hybrid map of the laboratory rat.

R G Steen, E. Lander, J. Rothberg, 1999, Genome research.

A quantitative genomic expression analysis platform for multiplexed in vitro prediction of drug action

J. Rothberg, D. Stone, R. Gerwien, 2005, The Pharmacogenomics Journal.

34.1 An 8960-Element Ultrasound-on-Chip for Point-of-Care Ultrasound

Hamid Soleimani, Liewei Bao, Kailiang Chen, 2021, 2021 IEEE International Solid- State Circuits Conference (ISSCC).

An integrated semiconductor device enabling non-optical genome sequencing

Bernard P. Puc, J. Rothberg, W. Hinz, 2011, Nature.

Droplet microfluidic technology for single-cell high-throughput screening

N. Perrimon, J. Rothberg, D. Marran, 2009, Proceedings of the National Academy of Sciences.

Cramming more sequencing reactions onto microreactor chips.

J. Rothberg, J. Leamon, Jonathan M Rothberg, 2007, Chemical reviews.

Inaugural Article: Patterns of nucleotide misincorporations during enzymatic amplification and direct large-scale sequencing of ancient DNA

J. Rothberg, J. Simons, W. He, 2006 .

Development of the Ion Torrent CMOS chip for DNA sequencing

J. Rothberg, J. Bustillo, B. Merriman, 2013, 2013 IEEE International Electron Devices Meeting.

Introduction

J. Rothberg, B. Merriman, Gadareth Higgs, 2012, The Yale journal of biology and medicine.