J. Dearden

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QSPR prediction of physico-chemical properties for REACH

J. Dearden, P. Rotureau, G. Fayet, 2013, SAR and QSAR in environmental research.

MIS Is a Mirage.

J. Dearden, 1972 .

In silico prediction of aqueous solubility

J. Dearden, 2006, Expert opinion on drug discovery.

Predicting Fate-Related Physicochemical Properties

J. Dearden, G. Schüürmann, R. Kühne, 2007 .

QSAR modeling: where have you been? Where are you going to?

J. Dearden, R. Todeschini, R. Cramer, 2014, Journal of medicinal chemistry.

Assessment and modeling of the toxicity of organic chemicals to Chlorella vulgaris: development of a novel database.

J. Dearden, M. Cronin, R. Edwards, 2004, Chemical research in toxicology.

The History and Development of Quantitative Structure-Activity Relationships (QSARs)

J. Dearden, 2016 .

Design, synthesis, computational and biological evaluation of new anxiolytics.

J. Dearden, V. Poroikov, D. Filimonov, 2004, Bioorganic & medicinal chemistry.

Design of new cognition enhancers: from computer prediction to synthesis and biological evaluation.

J. Dearden, V. Poroikov, D. Filimonov, 2004, Journal of medicinal chemistry.

QSAR in Toxicology. 1. Prediction of Aquatic Toxicity

J. Dearden, M. Cronin, 1995 .

Effect of the structural factors of organic compounds on the acute toxicity toward Daphnia magna

J. Dearden, O. Tinkov, V. Grigorev, 2020, SAR and QSAR in environmental research.

Linear QSAR regression models for the prediction of bioconcentration factors by physicochemical properties and structural theoretical molecular descriptors.

J. Dearden, P. Gramatica, E. Papa, 2007, Chemosphere.

In Silico Prediction of Physicochemical Properties

J. Dearden, A. Worth, Andrew Paul Worth, 2007 .

How not to develop a quantitative structure–activity or structure–property relationship (QSAR/QSPR)

J. Dearden, M. Cronin, K. Kaiser, 2009, SAR and QSAR in environmental research.

The intrinsic aqueous solubility of indomethacin

J. Dearden, J. Goodman, J. Comer, 2014 .

Quantitative Structure-Activity Relationships (QSAR) in Drug Design

Mark T. D. Cronin, John C. Dearden, J. Dearden, 2005 .

Quantitative structure-activity relationships (QSAR) and odour

John C. Dearden, J. Dearden, 1994 .

QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIPS IN THE PREDICTION OF PENICILLIN IMMUNOTOXICITY

J. Dearden, A. Bartlett, P. Sibley, 1995 .

Guidelines for developing and using quantitative structure‐activity relationships

John C Dearden, Joanna Jaworska, John D. Walker, 2003, Environmental toxicology and chemistry.

The Use of Topological Indices in QSAR and QSPR Modeling

J. Dearden, 2017 .

QSAR studies on P-glycoprotein-regulated multidrug resistance and on its reversal by phenothiazines*

J. Dearden, S. A. Thomson, A. Al-Noobi, 2003, SAR and QSAR in environmental research.

The Measurement of Partition Coefficients

John C. Dearden, J. Dearden, G. Bresnen, 1988 .

The Use of Atomic Charges and Orbital Energies as Hydrogen‐bonding‐donor Parameters for QSAR Studies: Comparison of MNDO, AM1 and PM3 Methods

J. Dearden, T. Ghafourian, 2000, The Journal of pharmacy and pharmacology.

An Investigation of the Mechanism of Flux Across Polydimethylsiloxane Membranes by use of Quantitative Structure‐Permeability Relationships

G P Moss, J. Dearden, M. Cronin, 1998, The Journal of pharmacy and pharmacology.

Quantitative Structure-Biodegradability Studies: An Investigation of the Miti Aromatic Compound Data-Base

J. Dearden, M. Cronin, 1996 .

Partitioning and lipophilicity in quantitative structure-activity relationships.

J. Dearden, J C Dearden, 1985, Environmental health perspectives.

Managing computer-based information systems

F. Warren McFarlan, William M. Zani, John Dearden, 1971 .

QSAR modelling of bioconcentration factor using hydrophobicity, hydrogen bonding and topological descriptors

J. Dearden, M. Hewitt, 2010, SAR and QSAR in environmental research.

Quantitative structure-activity-activity and quantitative structure-activity investigations of human and rodent toxicity.

Andrew P Worth, John C Dearden, Mark T D Cronin, 2006, Chemosphere.

Quantitative structure‐property relationships for prediction of boiling point, vapor pressure, and melting point

John C Dearden, J. Dearden, 2003, Environmental toxicology and chemistry.

Prediction of physicochemical properties.

John C Dearden, J. Dearden, 2012, Methods in molecular biology.

Henry's law constant of hydrocarbons in air–water system: The cavity ovality effect on the non-electrostatic contribution term of solvation free energy

J. Dearden, H. Modarress, H. Modarresi, 2005, SAR and QSAR in environmental research.

QSAR study of some anti-hyperglycaemic sulphonylurea drugs

J. Dearden, M. Hewitt, P. Rowe, 2015, SAR and QSAR in environmental research.

Computer Regression Models for P-Glycoprotein Transport of Drugs

J. Dearden, S. Solodova, V. Grigorev, 2019, Pharmaceutical Chemistry Journal.

Six global and local QSPR models of aqueous solubility at pH = 7.4 based on structural similarity and physicochemical descriptors

J. Dearden, O. Raevsky, V. Grigor'ev, 2017, SAR and QSAR in environmental research.

Aqueous Drug Solubility: What Do We Measure, Calculate and QSPR Predict?

J. Dearden, V. Grigorev, O. Raevsky, 2019, Mini reviews in medicinal chemistry.

The importance of hydrophobicity and electrophilicity descriptors in mechanistically-based QSARs for toxicological endpoints

M T D Cronin, A P Worth, N Manga, 2002, SAR and QSAR in environmental research.

Management control systems : cases and readings

John Dearden, Robert Newton Anthony, Richard F. Vancil, 1965 .

Correspondence Analysis of the Skin Sensitization Potential of Organic Chemicals

J. Dearden, M. Cronin, 1997 .

Hydrogen Bonding Parameters for QSAR: Comparison of Indicator Variables, Hydrogen Bond Counts, Molecular Orbital and Other Parameters.

J. Dearden, T. Ghafourian, 1999 .

In silico Prediction of Aqueous Solubility: a Comparative Study of Local and Global Predictive Models

J. Dearden, V. Grigorev, O. Raevsky, 2015, Molecular informatics.

Contribution assessment of multiparameter optimization descriptors in CNS penetration

J. Dearden, V. Grigorev, O. Raevsky, 2018, SAR and QSAR in environmental research.

A DOUBLE‐PEAKED QUANTITIVE STRUCTURE‐ACTIVITY RELATIONSHIP (QSAR) IN A SERIES OF PARACETAMOL DERIVATIVES

J. Dearden, M. Townend, Mrs. J.H. O'Hara, 1980 .

Use of Molecular Similarity Indices for QSAR Training Set Selection

J. Dearden, M. Cronin, I. Cousins, 1995 .

Study of local anesthetic activity of some derivatives of 3-amino-BENZO-[d]-Isothiazole

J. Dearden, V. Poroikov, A. Lagunin, 2003, SAR and QSAR in environmental research.

The Development and Validation of Expert Systems for Predicting Toxicity

Romualdo Benigni, Robert D. Combes, Philip N. Judson, 1997 .

Computer modelling studies of time-variant biological response†

J. Dearden, M. Townend, 1979 .

Quantitative approaches to drug design : proceedings of the Fourth European Symposium on Chemical Structure-Biological Activity: Quantitative Approaches, Bath, U.K., September 6-9, 1982

J. Dearden, 1983 .

Management control systems : text and cases

John Dearden, Robert Newton Anthony, J. Dearden, 1976 .

THERMODYNAMICS OF PARTITIONING ‐ ABSENCE OF CONSTANT HYDROPHOBIC EFFECT OF INTRAMOLECULAR HYDROGEN BONDING

J. Dearden, Mrs. G.M. Bresnen, 1982 .

PARTITIONING RATE CONSTANT AS A PARAMETER IN QUANTITIVE STRUCTURE‐ACTIVITY RELATIONSHIPS (QSARS)

J. Dearden, Mrs. G.M. Bresnen, 1980 .

Stability of aspirin derivatives to hydrolysis.

J. Dearden, E. George, 1979, Pharmaceutica acta Helvetiae.

USE OF A PHYSICAL MULTI‐CELL MODEL TO CONFIRM THEORETICAL PREDICTIONS OF BIPHASIC STRUCTURE‐ACTIVITY RELATIONSHIPS

J. Dearden, K. Patel, 1978, The Journal of pharmacy and pharmacology.

QUANTITATIVE STRUCTURE‐ACTIVITY STUDY OF INHIBITION OF BLOOD PLATELET AGGREGATION BY ASPIRIN DERIVATIVES

J. Dearden, E. George, 1977 .

THE RAPID DETERMINATION OF PARTITION COEFFICIENTS DATA USING A CONTINUOUS SOLVENT EXTRACTION SYSTEM (AKUFVE)

J. Dearden, S. Davis, E. Tomlinson, 1976 .

Quantitative structure-analgesic activity studies of some alkyl derivatives of paracetamol (4-hydroxyacetanilide [proceeding].

J. Dearden, J. H. O'Hara, 1976, The Journal of pharmacy and pharmacology.

Proceedings: Steric enhancement of resonance: an explanation of the anomalously high partition coefficients of some phenoxyacetic acids.

J. Dearden, J. C. Wootton, 1975, The Journal of pharmacy and pharmacology.

Correlation of chromatographically obtained substituent constants and analgesic activity.

J. Dearden, E. Tomlinson, 1972, The Journal of pharmacy and pharmacology.

Management information systems : text and cases

F. Warren McFarlan, John Dearden, John Dearden, 1966 .

Computer Modelling and Information Technology

David Bawden, John C. Dearden, Michael S. Tute, 1991 .

QSAR studies of comparative toxicity in aquatic organisms.

J. Dearden, M. Cronin, A. J. Dobbs, 1991, The Science of the total environment.

Toxicological Evaluation and QSAR Modelling of Aromatic Amines to Chlorella vulgaris

J. Dearden, M. Cronin, R. Edwards, 2004, Bulletin of environmental contamination and toxicology.

Stretched and Sheared Microcatheter Retained after Onyx Embolization of Infantile Myofibromatosis

J. Dearden, D. Orbach, C. Lillehei, 2011, Interventional Neuroradiology.

Correlation between gastric irritancy and anti‐inflammatory activity of non‐steroidal anti‐inflammatory drugs

J. Dearden, R. M. Nicholson, 1984, The Journal of pharmacy and pharmacology.

Correlation of tumour-inhibiting activity with acute toxicity.

J. Dearden, S. Bradburne, 1991, The Science of the total environment.

Relationship of physicochemical properties of isometric trifluoromethylphenols with their bactericidal effect on Escherichia coli.

J. Dearden, G. Weeks, 1973, Journal of pharmaceutical sciences.

Prediction of Human Lethality of Psychoactive Drugs From Rodent LD50 Values

J. Dearden, 2019, International Journal of Quantitative Structure-Property Relationships.

Quantitative Cationic Activity Relationships for Predicting Toxicity of Metal Ions from Physicochemical Properties and Natural Occurrence Levels

John D. Walker, J. Dearden, M. Enache, 2007 .

Computer Regression Models for P-Glycoprotein Transport of Drugs

J. Dearden, V. Grigorev, O. Raevsky, 2019, Pharmaceutical Chemistry Journal.

Management control systems : text, cases, and readings

John Dearden, Robert Newton Anthony, Richard F. Vancil, 1972 .

Descriptors and techniques for quantitative structure-biodegradability studies.

J. Dearden, 1996, SAR and QSAR in environmental research.

Correlation of Biodegradability with Atomic Charge Difference and Superdelocalizability

J. Dearden, R. M. Nicholson, 1987 .

LIGHT ABSORPTION STUDIES: PART XIV. THE ULTRAVIOLET ABSORPTION SPECTRA OF PHENOLS

J. Dearden, W. Forbes, 1959 .

2-Heteroarylimino-5-benzylidene-4-thiazolidinones analogues of 2-thiazolylimino-5-benzylidene-4-thiazolidinones with antimicrobial activity: synthesis and structure-activity relationship.

J. Dearden, M. Hewitt, A. Geronikaki, 2008, Bioorganic & medicinal chemistry.

EFFECT OF LIPOPHILICITY OF IONISABLE DRUGS ON DEVIATIONS FROM EXPECTED PH‐PARTITION BEHAVIOUR

J. Dearden, E. George, 1978, The Journal of pharmacy and pharmacology.

Evaluation of the local anaesthetic activity of 3-aminobenzo[d]isothiazole derivatives using the rat sciatic nerve model.

J. Dearden, V. Poroikov, M. Hewitt, 2009, European journal of medicinal chemistry.

Design, synthesis and biological testing of a novel series of anti‐inflammatory drugs

J. Dearden, C. Rostron, J. Duffy, 2001, The Journal of pharmacy and pharmacology.

LIGHT ABSORPTION STUDIES: PART XII. ULTRAVIOLET ABSORPTION SPECTRA OF BENZALDEHYDES

J. Dearden, W. Forbes, 1958 .

Structure-based classification of antibacterial activity.

Gerrit Schüürmann, Konstantinos Voutzoulidis, J. Dearden, 2002, Journal of chemical information and computer sciences.

QSAR study of the toxicity of benzoic acids to Vibrio fischeri, Daphnia magna and carp.

J. Dearden, M. Cronin, Y. H. Zhao, 1998, The Science of the total environment.

Thermodynamics of Water-octanol and Water-cyclohexane Partitioning of some Aromatic Compounds

J. Dearden, G. Bresnen, 2005 .

Determination of anti-oxidant activity by electron spin resonance spectroscopy.

J. Dearden, M. Cronin, H. Morris, 2000 .

QSAR analysis of metal ion toxicity data in sunflower callus cultures (Helianthus annuus “Sunspot”)

John D. Walker, J. Dearden, M. Enache, 2003 .

QSAR modeling of soil sorption.

J. Dearden, M. Cronin, D. Livingstone, 2004 .

Quantitative structure-permeability relationships (QSPRs) for percutaneous absorption.

M T D Cronin, G P Moss, J. Dearden, 2002, Toxicology in vitro : an international journal published in association with BIBRA.

The prediction of melting point

J. Dearden, 1999 .

Quantitative Structure-Activity Relationships of Chemicals Acting by Non-polar Narcosis—Theoretical Considerations

Mark T. D. Cronin, John C. Dearden, J. Dearden, 1998 .

In silico prediction of drug toxicity

John C. Dearden, J. Dearden, 2003, J. Comput. Aided Mol. Des..

THE STUDY OF HYDROGEN BONDING AND RELATED PHENOMENA BY ULTRAVIOLET LIGHT ABSORPTION: PART IV. INTERMOLECULAR HYDROGEN BONDING IN ANILINES AND PHENOLS

J. Dearden, W. Forbes, 1960 .

LIGHT ABSORPTION STUDIES: PART XV. THE ULTRAVIOLET ABSORPTION SPECTRA OF ANISOLES

J. Dearden, W. Forbes, 1959 .

Quantitative cationic‐activity relationships for predicting toxicity of metals

John D. Walker, J. Dearden, M. Enache, 2003, Environmental toxicology and chemistry.

The Integrated Use of Alternative Approaches for Predicting Toxic Hazard

Alessandro Giuliani, Robert D. Combes, Peter Zbinden, 1995 .

INVESTIGATION OF THE SELF-ASSOCIATION OF PHENOLS AND ANILINES BY ULTRAVIOLET SPECTROSCOPY

J. Dearden, 1963 .

Use of artificial neural networks in the QSAR prediction of physicochemical properties and toxicities for REACH legislation.

John C Dearden, Philip H Rowe, J. Dearden, 2015, Methods in molecular biology.

Structural basis for the haemotoxicity of dapsone: the importance of the sulphonyl group.

J. Dearden, M. Cronin, B. K. Park, 1997, Toxicology.

Structure-Based Classification of Antibacterial Activity

Mark T. D. Cronin, Andrew P. Worth, T. Wayne Schultz, 2002, J. Chem. Inf. Comput. Sci..

Physicochemical property profile for brain permeability: comparative study by different approaches

Oleg A Raevsky, John C Dearden, Veniamin Y Grigorev, 2016, Journal of drug targeting.

Correlation between vitamin D levels, individual and socio-demographic characteristics and COVID-19 infection and death rates in 20 European countries: A modelling study

J. Dearden, P. Rowe, 2020 .

Cost accounting comes to service industries.

J. Dearden, J Dearden, 1978, Harvard business review.

QSPR Prediction of Henry’s Law Constant: Improved Correlation with New Parameters

J. Dearden, M. Cronin, Shazia A. Ahmed, 2000 .

In Silico Prediction of Aqueous Solubility: The Solubility Challenge

Judith C. Madden, David W. Roberts, Mark T. D. Cronin, 2009, J. Chem. Inf. Model..

The prediction of biodegradability by the use of quantitative structure–activity relationships: Correlation of biological oxygen demand with atomic charge difference†

Robert M. Nicholson, John C. Dearden, J. Dearden, 1986 .

In silico prediction of ADMET properties: how far have we come?

John C Dearden, J. Dearden, 2007, Expert opinion on drug metabolism & toxicology.

The aquatic toxicity of anionic surfactants to Daphnia magna--a comparative QSAR study of linear alkylbenzene sulphonates and ester sulphonates.

J. Dearden, D. Roberts, G. Hodges, 2006, Chemosphere.

QSAR Study of the α1‐Adrenoceptor Antagonist Activity of WB4101 Derivatives

J. Dearden, M. Cronin, D. Mottram, 1998 .

Mechanism-Based QSAR Modeling of Skin Sensitization.

Girinath G. Pillai, K R Przybylak, D W Roberts, 2015, Chemical research in toxicology.

Prediction of Potential Cross‐reactivity Between β‐Lactam Antibiotics and Anti‐benzylpenicillin Serum Antibodies

J. Dearden, A. Bartlett, P. Sibley, 1996 .

THE STUDY OF HYDROGEN BONDING AND RELATED PHENOMENA BY ULTRAVIOLET LIGHT ABSORPTION: PART VI. THE EFFECT OF STERIC INTERACTIONS ON THE INTRAMOLECULAR HYDROGEN BOND IN o-NITROPHENOL

J. Dearden, W. Forbes, 1960 .

QSAR Investigation of New Cognition Enhancers

J. Dearden, M. Hewitt, A. Geronikaki, 2009 .

QSAR Analysis of the Toxicity of Aromatic Compounds to Chlorella vulgaris in a Novel Short-Term Assay

Mark T. D. Cronin, Robert Edwards, John C. Dearden, 2004, J. Chem. Inf. Model..

QSPR Correlation of Melting Point for Drug Compounds Based on Different Sources of Molecular Descriptors

John C. Dearden, Hamid Modarress, Hassan Modarresi, 2006, J. Chem. Inf. Model..

The wear of steel rails and tyres in railway service

J. Dearden, J. Dearden, 1960 .

Improved correlation between animal and human potency of non-steroidal anti-inflammatory drugs using quantitative structure–activity relationships (QSARs)

J. Dearden, M. Hewitt, G. Bresnen, 2017, SAR and QSAR in environmental research.

QSAR Modeling of Bioaccumulation

John Dearden, J. Dearden, 2004 .

Quantitative structure-activity study of the toxicity of benzonitriles to the ciliate Tetrahymena pyriformis.

T W Schultz, J. Dearden, M. Cronin, 1995, SAR and QSAR in environmental research.

A NOTE OF CAUTION TO USERS OF ECOSAR

John C. Dearden, Klaus L.E. Kaiser, J. Dearden, 1999 .

QSPR model of Henry's law constant for a diverse set of organic chemicals based on genetic algorithm-radial basis function network approach.

John C Dearden, Hamid Modarress, Hassan Modarresi, 2007, Chemosphere.

The QSAR prediction of melting point, a property of environmental relevance.

J. Dearden, J C Dearden, 1991, The Science of the total environment.

Quantitative structure‐property relationships for predicting henry's law constant from molecular structure

Gerrit Schüürmann, John C Dearden, J. Dearden, 2003, Environmental toxicology and chemistry.

Correction for effect of dilution on diffusion through a membrane.

J. Dearden, E. Tomlinson, 1971, Journal of Pharmacy and Science.

Buccal absorption as a parameter of analgesic activity of some p‐substituted acetanilides

J. Dearden, E. Tomlinson, 1971, The Journal of pharmacy and pharmacology.

Quantitative structure‐activity relationships for human health effects: Commonalities with other endpoints

Andrew P Worth, John C Dearden, Mark T D Cronin, 2003, Environmental toxicology and chemistry.

Correlation of physico‐chemical parameters with toxicity of metal ions to plants

J. Dearden, N. Lepp, M. Enache, 2000 .

Prediction of Human Lethal Doses and Concentrations of MEIC Chemicals from Rodent LD50 Values: An Attempt to Make Some Reparation

J. Dearden, M. Hewitt, 2021, Alternatives to laboratory animals : ATLA.

Nature of acetaminophen-antipyrine complex.

J. Dearden, 1972, Journal of pharmaceutical sciences.

The Development and Validation of Expert Systems for Predicting Toxicity The Report and Recommendations of an ECVAM / ECB Workshop ( ECVAM Workshop 24 )

Romualdo Benigni, Andrew P. Worth, Robert D. Combes, 2002 .

QSAR in Toxicology. 3. Prediction of Chronic Toxicities

Mark T. D. Cronin, John C. Dearden, J. Dearden, 1995 .

Investigation of the mechanism of flux across human skin in vitro by quantitative structure-permeability relationships.

G P Moss, J. Dearden, M. Cronin, 1999, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

A Qsar Study Of Anti‐Inflammatory N‐Arylanthranilic Acids

J. Dearden, C. Rostron, J. Duffy, 1996, The Journal of pharmacy and pharmacology.

The use of molecular electrostatic potentials as hydrogen-bonding-donor parameters for QSAR studies.

Taravat Ghafourian, John C Dearden, J. Dearden, 2004, Farmaco.

Prediction of environmental toxicity and fate using quantitative structure-activity relationships (QSARs)

J. Dearden, 2002 .

Management accounting : text and cases

J. Dearden, 1988 .

In Silico Prediction of Physicochemical Properties

J. Dearden, Andrew Paul Worth, 2007 .

Thermodynamics of Water-octanol and Water-cyclohexane Partitioning of some Aromatic Compounds

J. Dearden, G. Bresnen, 2005 .

Interval estimation of the median effective dose for a logistic dose-response curve

J. Dearden, S. Kirby, M. Hann, 1999 .

THE STUDY OF HYDROGEN BONDING AND RELATED PHENOMENA BY SPECTROSCOPIC METHODS: PART IX. THE ULTRAVIOLET ABSORPTION SPECTRUM OF 3-TRIFLUOROMETHYL-2- NITROPHENOL

J. Dearden, W. Forbes, A. Balasubramanian, 1966 .

QSAR in Toxicology. 4. Prediction of Non‐lethal Mammalian Toxicological Endpoints, and Expert Systems for Toxicity Prediction

Mark T. D. Cronin, John C. Dearden, J. Dearden, 1995 .

Defining the toxic mode of action of ester sulphonates using the joint toxicity of mixtures.

Geoff Hodges, John C Dearden, David W Roberts, 2006, Chemosphere.

Physicochemical property profile for brain permeability: comparative study by different approaches

J. Dearden, S. Bachurin, V. Grigorev, 2016, Journal of drug targeting.

Hydrogen Bonding Parameters for QSAR: Comparison of Indicator Variables, Hydrogen Bond Counts, Molecular Orbital and Other Parameters

Taravat Ghafourian, John C. Dearden, J. Dearden, 1999, J. Chem. Inf. Comput. Sci..