D. Curtis

发表

nanos is an evolutionarily conserved organizer of anterior-posterior polarity.

D. Curtis, J. Apfeld, R. Lehmann, 1995, Development.

SMN2 splice modulators enhance U1-pre-mRNA association and rescue SMA mice.

Thomas M. Smith, D. Curtis, B. Tseng, 2015, Nature chemical biology.

Systematic generation of high-resolution deletion coverage of the Drosophila melanogaster genome

D. Curtis, T. Kaufman, M. Belvin, 2004, Nature Genetics.

Translational regulation in development

Phillip D Zamore, Ruth Lehmann, D. Curtis, 1995, Cell.

Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling

Marc W. Kirschner, Feng Cong, Craig Mickanin, 2009, Nature.

Antisense Oligonucleotide-Induced Amyloid Precursor Protein Splicing Modulation as a Therapeutic Approach for Dutch-Type Cerebral Amyloid Angiopathy

D. Curtis, M. Verbeek, W. V. van Roon-Mom, 2021, Nucleic acid therapeutics.

Identification of cis-acting sequences that control nanos RNA localization.

D. Curtis, R. Lehmann, E. R. Gavis, 1996, Developmental biology.

aph-1 and pen-2 Are Required for Notch Pathway Signaling, γ-Secretase Cleavage of βAPP, and Presenilin Protein Accumulation

Wei Xu, Mark E. Gurney, M. C. Ellis, 2002 .

Discovery of a Brain Penetrant ATP-competitive Inhibitor of the Mechanistic Target of Rapamycin (mTOR) for CNS disorders.

D. Curtis, F. Lombardo, Christopher J. Wilson, 2020, Journal of medicinal chemistry.

Corrigendum: SMN2 splice modulators enhance U1-pre-mRNA association and rescue SMA mice.

Thomas M. Smith, John A. Tallarico, D. Curtis, 2015, Nature chemical biology.

Discovery of Small Molecule Splicing Modulators of Survival Motor Neuron-2 (SMN2) for the Treatment of Spinal Muscular Atrophy (SMA).

D. Curtis, M. Hild, Yiping Shen, 2018, Journal of medicinal chemistry.

Presenilin-Based Genetic Screens in Drosophila melanogaster Identify Novel Notch Pathway Modifiers

M. C. Ellis, D. Curtis, F. Mapa, 2006, Genetics.

Genetic circuitry of Survival motor neuron, the gene underlying spinal muscular atrophy

D. Curtis, S. Brachat, D. Richardson, 2013, Proceedings of the National Academy of Sciences.

Integrated compound profiling screens identify the mitochondrial electron transport chain as the molecular target of the natural products manassantin, sesquicillin, and arctigenin.

J. D. Benson, D. Curtis, D. Selinger, 2013, ACS chemical biology.

Huntingtin cleavage product A forms in neurons and is reduced by gamma-secretase inhibitors

Dimitri Krainc, D. Curtis, D. Krainc, 2010, Molecular Neurodegeneration.

aph-1 and pen-2 are required for Notch pathway signaling, gamma-secretase cleavage of betaAPP, and presenilin protein accumulation.

M. C. Ellis, D. Curtis, J. Apfeld, 2002, Developmental cell.

Presenilin diversifies its portfolio.

D. Curtis, A. Parks, 2007, Trends in genetics : TIG.

A CCHC metal‐binding domain in Nanos is essential for translational regulation

D. Curtis, R. Lehmann, P. Zamore, 1997, The EMBO journal.

Unique Regulation of the DosR Regulon in the Beijing Lineage of Mycobacterium tuberculosis

D. Curtis, M. Reed, A. Averback, 2016, Journal of bacteriology.

Seizure reduction in TSC2-mutant mouse model by an mTOR catalytic inhibitor.

D. Curtis, Christopher J. Wilson, A. Rotenberg, 2023, Annals of clinical and translational neurology.

Identification of Brain-Penetrant ATP-Competitive mTOR Inhibitors for CNS Syndromes.

D. Curtis, Christopher J. Wilson, P. Furet, 2023, Journal of Medicinal Chemistry.

SMN2 splice modulators enhance U1-pre-mRNA association and rescue SMA mice.

Thomas M. Smith, John A. Tallarico, D. Curtis, 2015, Nature chemical biology.