Jason A. Wiles

发表

Effects of Surface Modification and Moisture on the Rates of Charge Transfer between Metals and Organic Materials

G. Whitesides, Jason A. Wiles, M. Fiałkowski, 2004 .

A tool for studying contact electrification in systems comprising metals and insulating polymers.

Bartosz A Grzybowski, George M Whitesides, G. Whitesides, 2003, Analytical chemistry.

Electrostatic self-assembly of macroscopic crystals using contact electrification

George M. Whitesides, Bartosz A. Grzybowski, G. Whitesides, 2003, Nature materials.

New quinolone antibiotics: a survey of the literature from 2005 to 2010

Jason A. Wiles, M. Pucci, Michael J Pucci, 2010, Expert opinion on therapeutic patents.

Bacterial Topoisomerase Inhibitors: Quinolones and Beyond

Jason A. Wiles, M. Pucci, 2014 .

Selenophene-containing inhibitors of type IIA bacterial topoisomerases.

Jason A. Wiles, M. Deshpande, A. Phadke, 2011, Journal of medicinal chemistry.

Isothiazolopyridones: synthesis, structure, and biological activity of a new class of antibacterial agents.

Jason A. Wiles, M. Deshpande, C. Incarvito, 2006, Journal of medicinal chemistry.

Isothiazoloquinolones with enhanced antistaphylococcal activities against multidrug-resistant strains: effects of structural modifications at the 6-, 7-, and 8-positions.

Jason A. Wiles, M. Deshpande, M. Pucci, 2007, Journal of medicinal chemistry.

A Versatile and High-Yield Route to Active and Well-Defined Catalysts [Ru(bisphosphane)(H)(solvent)3 ](BF4 ).

Jason A. Wiles, S. Bergens, K. Vanhessche, 2001, Angewandte Chemie.

Ferrocene-based inhibitors of hepatitis C virus replication that target NS5A with low picomolar in vitro antiviral activity.

Jason A. Wiles, Wen-gang Yang, M. Deshpande, 2018, Bioorganic & medicinal chemistry letters.

Application of [Ru((R)-BINAP)(MeCN)(1-3:5,6-η-C8H11)](BF4) as a catalyst precursor for enantioselective hydrogenations

Jason A. Wiles, S. Bergens, C. J. Daley, 1998 .

Isothiazoloquinolones containing functionalized aromatic hydrocarbons at the 7-position: synthesis and in vitro activity of a series of potent antibacterial agents with diminished cytotoxicity in human cells.

Jason A. Wiles, M. Deshpande, M. Pucci, 2006, Bioorganic & medicinal chemistry letters.

Biological evaluation of isothiazoloquinolones containing aromatic heterocycles at the 7-position: In vitro activity of a series of potent antibacterial agents that are effective against methicillin-resistant Staphylococcus aureus.

Jason A. Wiles, M. Deshpande, M. Pucci, 2006, Bioorganic & medicinal chemistry letters.

Kinetics of contact electrification between metals and polymers.

Bartosz A Grzybowski, Marcin Fialkowski, Jason A. Wiles, 2005, The journal of physical chemistry. B.

Exploration of the activity of 7-pyrrolidino-8-methoxyisothiazoloquinolones against methicillin-resistant Staphylococcus aureus (MRSA).

Jason A. Wiles, M. Deshpande, M. Pucci, 2011, Journal of medicinal chemistry.

Practical Synthesis and Molecular Structure of a Potent Broad-Spectrum Antibacterial Isothiazoloquinolone

Jason A. Wiles, M. Deshpande, C. Incarvito, 2007 .

Substrate effects on the mechanism of enantioselective hydrogenation using ruthenium bis(phosphine) complexes as catalyst: A mechanistic investigation of the hydrogenation of α,β-unsaturated acids and esters based on deuterium labeling studies

Jason A. Wiles, S. Bergens, C. J. Daley, 2006 .

The First Structure Determination of a Diastereomeric Hydrido−Olefin Putative Intermediate in Catalytic Enantioselective Hydrogenation

Jason A. Wiles, S. Bergens, 1999 .

Mechanistic Investigations of an Enantioselective Hydrogenation Catalyzed by a Ruthenium−BINAP Complex. 1. Stoichiometric and Catalytic Labeling Studies

Jason A. Wiles, S. Bergens, 1998 .

845 PRECLINICAL CHARACTERISTICS OF ACH-3102: A NOVEL HCV NS5A INHIBITOR WITH IMPROVED POTENCY AGAINST GENOTYPE-1A VIRUS AND VARIANTS RESISTANT TO 1ST GENERATION OF NS5A INHIBITORS

Jason A. Wiles, M. Deshpande, A. Phadke, 2012 .

Discovery and Development of the Oral Complement Factor D Inhibitor ACH-4471.

Jason A. Wiles, M. Galvan, M. Geffner, 2019, Current medicinal chemistry.

Development of a Commercial Process for Odalasvir

Jason A. Wiles, A. Hashimoto, A. Phadke, 2021, Organic Process Research & Development.

Small molecule inhibitors of E. coli primase, a novel bacterial target.

Jason A. Wiles, S. Louise-May, A. Agarwal, 2007, Bioorganic & medicinal chemistry letters.

Preclinical Evaluation of Orally Bioavailable Small-Molecule Inhibitors of Complement Factor D as a Potential Treatment for Paroxysmal Nocturnal Hemoglobinuria

Jason A. Wiles, A. Agarwal, M. Deshpande, 2014 .

Novel Small-Molecule Inhibitors Targeting Complement Factor D for Therapy of Paroxysmal Nocturnal Hemoglobinuria

Jason A. Wiles, A. Agarwal, M. Deshpande, 2014 .

Dynamic self-assembly of rings of charged metallic spheres.

Bartosz A Grzybowski, George M Whitesides, G. Whitesides, 2003, Physical review letters.

Comparison of complement functional assays: Differential sensitivities of hemolysis and Wieslab assays to levels of complement proteins C5, factor B, and factor D

Jason A. Wiles, Wen-gang Yang, A. Phadke, 2016 .

Danicopan, an Oral Complement Factor D Inhibitor, Exhibits High and Sustained Exposure in Ocular Tissues in Preclinical Studies

Jason A. Wiles, Xiang Gao, M. Cartwright, 2022, Translational vision science & technology.

Tethered Diarenes as Four-Site Donors to SbCl3

Jason A. Wiles, J. Clyburne, N. Burford, 1996 .