D. Henze

发表

Quantitative measures of cluster quality for use in extracellular recordings

Jadin C. Jackson, A. Redish, K. Harris, 2005, Neuroscience.

Accuracy of tetrode spike separation as determined by simultaneous intracellular and extracellular measurements.

J. Csicsvari, G. Buzsáki, K. Harris, 2000, Journal of neurophysiology.

On the origin of the extracellular action potential waveform: A modeling study.

C. Koch, G. Buzsáki, D. Henze, 2006, Journal of neurophysiology.

Massively parallel recording of unit and local field potentials with silicon-based electrodes.

J. Csicsvari, G. Buzsáki, K. Harris, 2003, Journal of neurophysiology.

Intracellular features predicted by extracellular recordings in the hippocampus in vivo.

J. Csicsvari, G. Buzsáki, K. Harris, 2000, Journal of neurophysiology.

Temporal Interaction between Single Spikes and Complex Spike Bursts in Hippocampal Pyramidal Cells

G. Buzsáki, K. Harris, D. Henze, 2001, Neuron.

Spike train dynamics predicts theta-related phase precession in hippocampal pyramidal cells

G. Buzsáki, K. Harris, D. Henze, 2002, Nature.

Interneuron Diversity series: Circuit complexity and axon wiring economy of cortical interneurons

G. Buzsáki, D. Henze, Xiao-Jing Wang, 2004, Trends in Neurosciences.

Integration and Segregation of Activity in Entorhinal-Hippocampal Subregions by Neocortical Slow Oscillations

Sean M Montgomery, G. Buzsáki, D. Henze, 2006, Neuron.

Single granule cells reliably discharge targets in the hippocampal CA3 network in vivo

G. Buzsáki, D. Henze, L. Wittner, 2002, Nature Neuroscience.

Dendritic morphology and its effects on the amplitude and rise‐time of synaptic signals in hippocampal CA3 pyramidal cells

D. Henze, G. Barrionuevo, W. Cameron, 1996, The Journal of comparative neurology.

Single cell contributions to network activity in the hippocampus

György Buzsáki, Darrell A. Henze, G. Buzsáki, 2003 .

Revisiting the role of the hippocampal mossy fiber synapse

D. Henze, G. Barrionuevo, N. Urban, 2001, Hippocampus.

The multifarious hippocampal mossy fiber pathway: a review

D. Henze, G. Barrionuevo, N. Urban, 2000, Neuroscience.

Neuronal Diversity in GABAergic Long-Range Projections from the Hippocampus

P. Somogyi, G. Buzsáki, D. Henze, 2007, The Journal of Neuroscience.

Action potential threshold of hippocampal pyramidal cells in vivo is increased by recent spiking activity

G. Buzsáki, D. Henze, 2001, Neuroscience.

Antinociceptive effects of potent, selective and brain penetrant muscarinic M4 positive allosteric modulators in rodent pain models

D. Henze, H. Meziane, Sean M. Smith, 2020, Brain Research.

Ultra-slow oscillation (0.025 Hz) triggers hippocampal afterdischarges in Wistar rats

G Buzsáki, J. Csicsvari, G. Buzsáki, 1999, Neuroscience.

Selective reduction by dopamine of excitatory synaptic inputs to pyramidal neurons in primate prefrontal cortex

German Barrionuevo, D. Henze, D. Lewis, 2002, The Journal of physiology.

Dopamine modulation of neuronal function in the monkey prefrontal cortex

G. Barrionuevo, D. Henze, J. Seamans, 2002, Physiology & Behavior.

Dopamine increases excitability of pyramidal neurons in primate prefrontal cortex.

D. Henze, D. Lewis, G. Barrionuevo, 2000, Journal of neurophysiology.

Hippocampal Pyramidal Cell–Interneuron Spike Transmission Is Frequency Dependent and Responsible for Place Modulation of Interneuron Discharge

G. Buzsáki, D. Henze, H. Hirase, 2002, The Journal of Neuroscience.

MeasurementsIntracellular and Extracellular Accuracy of Tetrode Spike Separation as Determined by

J. Csicsvari, D. Henze, O. Paulsen, 2012 .

Waveform: A Modeling Study On the Origin of the Extracellular Action Potential

Christof Koch, György Buzsáki, Darrell A. Henze, 2006 .

Large Animal Models for Pain Therapeutic Development

D. Henze, M. Urban, 2010 .

Development of ProTx-II Analogues as Highly Selective Peptide Blockers of Nav1.7 for the Treatment of Pain.

D. Henze, S. Grauer, A. Palani, 2021, Journal of medicinal chemistry.

Association of respiratory failure with inhibition of NaV1.6 in the phrenic nerve

D. Henze, C. Regan, Yuxing Li, 2022, Channels.

Benzimidazole CB2 agonists: design, synthesis and SAR.

K. K. Nanda, D. Henze, Suzie Yeh, 2014, Bioorganic & medicinal chemistry letters.

Design, synthesis and SAR of substituted indoles as selective TrkA inhibitors.

D. Henze, Kartik Narayan, Tamara D. Cabalu, 2017, Bioorganic & medicinal chemistry letters.

Development of a pharmacodynamic biomarker to measure target engagement from inhibition of the NGF–TrkA pathway

K. K. Nanda, D. Henze, S. Stachel, 2017, Journal of Neuroscience Methods.

Homeostatic maintenance of neuronal excitability by burst discharges in vivo.

Jozsef Csicsvari, George Dragoi, György Buzsáki, 2002, Cerebral cortex.

Large amplitude miniature excitatory postsynaptic currents in hippocampal CA3 pyramidal neurons are of mossy fiber origin.

D. Henze, G. Barrionuevo, Y. Ben‐Ari, 1997, Journal of neurophysiology.

Imidazopyridine CB2 agonists: optimization of CB2/CB1 selectivity and implications for in vivo analgesic efficacy.

K. K. Nanda, D. Henze, Suzie Yeh, 2011, Bioorganic & medicinal chemistry letters.

Origin of the apparent asynchronous activity of hippocampal mossy fibers.

D. Henze, G. Barrionuevo, N. Urban, 1997, Journal of neurophysiology.

Hippocampal CA3 pyramidal cells selectively innervate aspiny interneurons

György Buzsáki, Lucia Wittner, László Záborszky, 2006, The European journal of neuroscience.

Recent Advances Toward Pain Therapeutics

D. Henze, P. Nantermet, 2011 .

Aspartate and glutamate mediate excitatory synaptic transmission in area CA1 of the hippocampus

D. Henze, G. Barrionuevo, MW Fleck, 1993, The Journal of neuroscience : the official journal of the Society for Neuroscience.

Hebbian modification of a hippocampal population pattern in the rat

G Buzsáki, G. Buzsáki, D. Henze, 1999, The Journal of physiology.

Giant miniature EPSCs at the hippocampal mossy fiber to CA3 pyramidal cell synapse are monoquantal.

K. Harris, D. Henze, G. Barrionuevo, 2002, Journal of neurophysiology.

Translational Pharmacokinetic–Pharmacodynamic Modeling of NaV1.7 Inhibitor MK-2075 to Inform Human Efficacious Dose

D. Henze, C. Gibson, R. Kraus, 2021, Frontiers in Pharmacology.

Application of Pharmacokinetic-Pharmacodynamic Modeling to Inform Translation of In Vitro NaV1.7 Inhibition to In Vivo Pharmacological Response in Non-human Primate

D. Henze, C. Gibson, Yuxing Li, 2020, Pharmaceutical Research.

Clozapine Potentiation of N-Methyl-d-aspartate Receptor Currents in the Nucleus Accumbens: Role of NR2B and Protein Kinase A/Src Kinases

D. Henze, P. Conn, G. Seabrook, 2005, Journal of Pharmacology and Experimental Therapeutics.

Structural characterization of nonactive site, TrkA-selective kinase inhibitors

D. Henze, H. Su, M. Ziebell, 2016, Proceedings of the National Academy of Sciences.

Maximizing diversity from a kinase screen: identification of novel and selective pan-Trk inhibitors for chronic pain.

Paul Zuck, K. K. Nanda, D. Henze, 2014, Journal of medicinal chemistry.

HC-030031, a TRPA1 selective antagonist, attenuates inflammatory- and neuropathy-induced mechanical hypersensitivity

D. Henze, M. Urban, S. R. Eid, 2008, Molecular pain.

Pharmacological validation of a novel nonhuman primate measure of thermal responsivity with utility for predicting analgesic effects

D. Henze, J. Uslaner, Joshua D. Vardigan, 2018, Journal of pain research.

Hilar mossy cells: functional identification and activity in vivo.

György Buzsáki, G. Buzsáki, D. Henze, 2007, Progress in brain research.

Three-dimensional reconstruction of the axon arbor of a CA3 pyramidal cell recorded and filled in vivo

György Buzsáki, Lucia Wittner, Darrell A. Henze, 2007, Brain Structure and Function.

The apical shaft of CA1 pyramidal cells is under GABAergic interneuronal control

G. Buzsáki, D. Henze, X. Leinekugel, 2001, Neuroscience.

Effects of a novel M4 muscarinic positive allosteric modulator on behavior and cognitive deficits relevant to Alzheimer's disease and schizophrenia in rhesus monkey

D. Henze, J. Uslaner, Joshua D. Vardigan, 2021, Neuropharmacology.

High concentration electrophysiology-based fragment screen: discovery of novel acid-sensing ion channel 3 (ASIC3) inhibitors.

Zhijian Zhao, James C Barrow, Scott T. Harrison, 2011, Bioorganic & medicinal chemistry letters.

Amplification of perforant-path EPSPs in CA3 pyramidal cells by LVA calcium and sodium channels.

D. Henze, G. Barrionuevo, N. Urban, 1998, Journal of Neurophysiology.

Nav1.7 target modulation and efficacy can be measured in nonhuman primate assays

D. Henze, Yuxing Li, R. Kraus, 2021, Science Translational Medicine.

Challenges faced in choosing novel targets to treat chronic pain.

D. Henze, 2009, Future medicinal chemistry.

Using extracellular action potential recordings to constrain compartmental models

Christof Koch, Carl Gold, Darrell A. Henze, 2007, Journal of Computational Neuroscience.

The role of amyloid-beta derived diffusible ligands (ADDLs) in Alzheimer's disease.

D. Henze, G. Krafft, J. Joyce, 2006, Current topics in medicinal chemistry.

High-Throughput Screen of GluK1 Receptor Identifies Selective Inhibitors with a Variety of Kinetic Profiles Using Fluorescence and Electrophysiology Assays

Michael F. Finley, D. Henze, M. Rudd, 2015, Journal of biomolecular screening.

Maintenance and Modification of Firing Rates and Sequences in the Hippocampus: Does Sleep Play a Role?

J. Csicsvari, G. Buzsáki, K. Harris, 2003 .

Decahydroquinoline amides as highly selective CB2 agonists: role of selectivity on in vivo efficacy in a rodent model of analgesia.

D. Henze, Suzie Yeh, G. Hartman, 2011, Bioorganic & medicinal chemistry letters.

Benzoxazolinone aryl sulfonamides as potent, selective Nav1.7 inhibitors with in vivo efficacy in a preclinical pain model.

Michael A Rossi, D. Henze, J. Majercak, 2017, Bioorganic & medicinal chemistry letters.

Maximizing diversity from a kinase screen: identification of novel and selective pan-Trk inhibitors for chronic pain.

K. K. Nanda, D. Henze, M. Rudd, 2014, Journal of medicinal chemistry.

Development of a pharmacodynamic biomarker to measure target engagement from inhibition of the NGF–TrkA pathway

K. K. Nanda, D. Henze, S. Stachel, 2017, Journal of Neuroscience Methods.