Z. Oltvai

发表

Lethality and centrality in protein networks

A. Barabasi, H. Jeong, S. Mason, 2001, Nature.

Network biology: understanding the cell's functional organization

A. Barabasi, Z. Oltvai, A. Barabási, 2004, Nature Reviews Genetics.

Hierarchical Organization of Modularity in Metabolic Networks

A. Barabasi, Z. Oltvai, E. Ravasz, 2002, Science.

Functional and topological characterization of protein interaction networks

A. Barabasi, Z. Oltvai, S. Yook, 2004, Proteomics.

Bioinformatics analysis of experimentally determined protein complexes in the yeast Saccharomyces cerevisiae.

A. Barabasi, Z. Oltvai, Z. Dezső, 2003, Genome research.

The implications of human metabolic network topology for disease comorbidity

Krin A. Kay, A. Barabasi, Z. Oltvai, 2008, Proceedings of the National Academy of Sciences.

Blueprint for antimicrobial hit discovery targeting metabolic networks

A. Barabasi, Z. Oltvai, D. Lee, 2010, Proceedings of the National Academy of Sciences.

Serine Biosynthesis with One Carbon Catabolism and the Glycine Cleavage System Represents a Novel Pathway for ATP Generation

Z. Oltvai, Alexei Vazquez, E. Markert, 2011, PloS one.

Identifying Ligand Binding Conformations of the β2-Adrenergic Receptor by Using Its Agonists as Computational Probes

Z. Oltvai, G. Estiu, B. Isin, 2012, PloS one.

Targets Drug Genomes Identify Novel Antimicrobial Staphylococcus Aureus of Multiple Reconstruction and Flux Balance Analysis Comparative Genome-scale Metabolic Supplemental Material

A. Barabasi, Z. Oltvai, E. Almaas, 2009 .

The topology of the transcription regulatory network in the yeast

A. Barabasi, H. Jeong, T. Vicsek, 2002, cond-mat/0205181.

Experimental Determination and System Level Analysis of Essential Genes in Escherichia coli MG1655

J. W. Campbell, J. W. Campbell, A. Barabasi, 2003, Journal of bacteriology.

Comparable system-level organization of Archaea and Eukaryotes

A. Barabasi, H. Jeong, Z. Oltvai, 2001, Nature Genetics.

Intracellular crowding defines the mode and sequence of substrate uptake by Escherichia coli and constrains its metabolic activity

M. A. de Menezes, A. Barabasi, Z. Oltvai, 2007, Proceedings of the National Academy of Sciences.

Adjustment in tumbling rates improves bacterial chemotaxis on obstacle-laden terrains

Z. Oltvai, Z. Bar-Joseph, S. Navlakha, 2019, Proceedings of the National Academy of Sciences.

Cell-cell communication enhances bacterial chemotaxis toward external attractants

Z. Oltvai, Zhicheng Long, H. Salman, 2017, Scientific Reports.

Macromolecular crowding explains overflow metabolism in cells

Z. Oltvai, Alexei Vazquez, 2016, Scientific Reports.

Molecular Crowding Defines a Common Origin for the Warburg Effect in Proliferating Cells and the Lactate Threshold in Muscle Physiology

Z. Oltvai, Alexei Vazquez, 2011, PloS one.

THE CELL ’ S FUNCTIONAL ORGANIZATION

A. Barabasi, Z. Oltvai, A. Barabási, 2004 .

Identification of motions in membrane proteins by elastic network models and their experimental validation.

Kalyan C. Tirupula, Z. Oltvai, J. Klein-Seetharaman, 2012, Methods in molecular biology.

Characteristics of biological networks

Albert-László Barabási, Zoltán N. Oltvai, Stefan Wuchty, 2004 .

Significance of p53 dynamics in regulating apoptosis in response to ionizing radiation, and polypharmacological strategies

Bing Liu, Ivet Bahar, Zoltán N. Oltvai, 2014, Scientific Reports.

Stochastic modeling of p53-regulated apoptosis upon radiation damage

Z. Oltvai, I. Bahar, D. Bhatt, 2011, 1109.0743.

Carbon catabolite repression correlates with the maintenance of near invariant molecular crowding in proliferating E. coli cells

Yi Zhou, Ziv Bar-Joseph, Zoltán N. Oltvai, 2013, BMC Systems Biology.

Interleukin-3 Induces the Phosphorylation of a Distinct Fraction of Bcl-2*

Z. Oltvai, P. B. Poommipanit, B. Chen, 1999, The Journal of Biological Chemistry.

Identification of novel bacterial histidine biosynthesis inhibitors using docking, ensemble rescoring, and whole-cell assays.

Z. Oltvai, G. Estiu, O. Wiest, 2010, Bioorganic & medicinal chemistry.

Bcl-2 promotes premature senescence induced by oncogenic Ras.

Z. Oltvai, B. Tombor, K. Rundell, 2003, Biochemical and biophysical research communications.

Bcl-2 gene family and the regulation of programmed cell death.

Z. Oltvai, S. Korsmeyer, G. Linette, 1994, Cold Spring Harbor symposia on quantitative biology.

Utility of Select Gene Mutation Detection in Tumors by the Idylla Rapid Multiplex PCR Platform in Comparison to Next-Generation Sequencing

Z. Oltvai, C. Syposs, D. Nkosi, 2022, Genes.

Incidental discovery of acute myeloid leukemia during liquid biopsy of a lung cancer patient

Z. Oltvai, A. Jajosky, Caroline A. Miller, 2022, Cold Spring Harbor molecular case studies.

Sensing Your Surroundings: How Transcription-Regulatory Networks of the Cell Discern Environmental Signals

Z. Oltvai, G. Balázsi, 2005, Science's STKE.

Quantitative assessment of cell fate decision between autophagy and apoptosis

Z. Oltvai, I. Bahar, H. Bayır, 2017, bioRxiv.

Serine biosynthesis with one carbon catabolism represents a novel pathway for ATP generation in cells using alternative glycolysis with zero net ATP production

Z. Oltvai, A. Vazquez, 2011 .

Reactive oxygen species and the regulation of cell death by the Bcl-2 gene family.

Z. Oltvai, G. Linette, S. Korsmeyer, 1995, Biochimica et biophysica acta.

Osteopontin contributes to hepatocyte growth factor-induced tumor growth and metastasis formation.

Z. Oltvai, A. Rademaker, D. Solt, 2003, Experimental cell research.

Checkpoints of dueling dimers foil death wishes

Z. Oltvai, S. Korsmeyer, 1994, Cell.

Shift from stochastic to spatially-ordered expression of serine-glycine synthesis enzymes in 3D microtumors

Robin E. C. Lee, Z. Oltvai, J. Faeder, 2018, Scientific Reports.

Intracellular crowding of macromolecules defines the mode and sequence of substrate uptake by E . coli and constrains its metabolic activity and growth Supporting Information , Part 2 : Experimental protocols and microarray analyses

A. Barabasi, Z. Oltvai, Z. Bar-Joseph, 2007 .

Exploring Transcriptional Regulatory Networks in the Worm

I. Farkas, Z. Oltvai, Q. Beg, 2006, Cell.

The ability of Bcl-x(L) and Bcl-2 to prevent apoptosis can be differentially regulated.

Z. Oltvai, S. Korsmeyer, C. Thompson, 1996, Cell Death and Differentiation.

Exploration of inflammatory biomarkers in three depots of adipose tissue in women with endometrial cancer 2

Justin S. Weinbaum, M. Gladwin, Z. Oltvai, 2017 .

Alterations in the omics profiles in mevalonate pathway-inhibited cancer cells.

Z. Oltvai, K. Warita, Yaxuan Zhou, 2022, Life sciences.

The large-scale organization of metabolic networks

R. Albert, H. Jeong, B. Tombor, 2000, Nature.

Evolutionary conservation of motif constituents in the yeast protein interaction network

Z N Oltvai, A-L Barabási, S Wuchty, 2003, Nature Genetics.

Bcl-2 functions in an antioxidant pathway to prevent apoptosis

Z. Oltvai, S. Korsmeyer, Xiao-Ming Yin, 1993, Cell.

The Activity Reaction Core and Plasticity of Metabolic Networks

Albert-László Barabási, Zoltán N. Oltvai, Eivind Almaas, 2005, PLoS Comput. Biol..

Impact of Limited Solvent Capacity on Metabolic Rate, Enzyme Activities, and Metabolite Concentrations of S. cerevisiae Glycolysis

Albert-László Barabási, Zoltán N. Oltvai, Alexei Vazquez, 2008, PLoS Comput. Biol..

Multiple Bcl-2 family members demonstrate selective dimerizations with Bax.

Z. Oltvai, S. Korsmeyer, C. Thompson, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Statin drugs to reduce breast cancer recurrence and mortality

Z. Oltvai, A. Wells, A. Brufsky, 2018, Breast Cancer Research.

Rhapsody: predicting the pathogenicity of human missense variants

Luca Ponzoni, Ivet Bahar, Zoltán N Oltvai, 2020, Bioinform..

Rhapsody: Pathogenicity prediction of human missense variants based on protein sequence, structure and dynamics

Luca Ponzoni, Ivet Bahar, Zoltán N. Oltvai, 2019, bioRxiv.

Quantitative assessment of cell fate decision between autophagy and apoptosis

Z. Oltvai, I. Bahar, H. Bayır, 2017, bioRxiv.

Life's Complexity Pyramid

Albert-László Barabási, Zoltán N. Oltvai, A. Barabasi, 2002, Science.

A Semi-Supervised Method for Predicting Transcription Factor–Gene Interactions in Escherichia coli

Ziv Bar-Joseph, Zoltán N. Oltvai, Jason Ernst, 2008, PLoS Comput. Biol..

Heterodimerization with Bax is required for Bcl-2 to repress cell death.

Z. Oltvai, S. Korsmeyer, S. Korsmeyer, 1995, Current topics in microbiology and immunology.

BMC Systems Biology

Gilles Clermont, Boris S. Gutkin, Pablo Villoslada, 2022 .

BH1 and BH2 domains of Bcl-2 are required for inhibition of apoptosis and heterodimerization with Bax

Z. Oltvai, S. Korsmeyer, Xiao-Ming Yin, 1994, Nature.

Bcl-2 Counters Apoptosis by Bax Heterodimerization-dependent and -independent Mechanisms in the T-cell Lineage*

Z. Oltvai, S. Anderson, Eric G. St. Clair, 1997, The Journal of Biological Chemistry.

Aggregation of topological motifs in the Escherichia coli transcriptional regulatory network

Albert-László Barabási, Radu Dobrin, Zoltán N. Oltvai, 2004, BMC Bioinformatics.

Statins attenuate outgrowth of breast cancer metastases

Z. Oltvai, A. Wells, A. Clark, 2018, British Journal of Cancer.

Bcl-2/Bax: a rheostat that regulates an anti-oxidant pathway and cell death.

Z. Oltvai, S. Korsmeyer, J. Shutter, 1993, Seminars in cancer biology.

Contribution of serine, folate and glycine metabolism to the ATP, NADPH and purine requirements of cancer cells

Z N Oltvai, L G Boros, Z. Oltvai, 2013, Cell Death and Disease.

The topological relationship between the large-scale attributes and local interaction patterns of complex networks

A Vázquez, R Dobrin, D Sergi, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Genetic Dissection of Transcriptional Regulation in Budding Yeast

Albert-László Barabási, Z. N. Oltvai, Hawoong Jeong, 2002 .

Shift from stochastic to spatially-ordered expression of serine-glycine synthesis enzymes in 3D microtumors

Z. Oltvai, J. Faeder, S. Sant, 2018, Scientific Reports.

The metabolic demands of cancer cells are coupled to their size and protein synthesis rates

Jean Qiu, Zoltán N Oltvai, Leo Li-Ying Chan, 2013, Cancer & Metabolism.

Role of membrane anchor domain of Bcl-2 in suppression of apoptosis caused by E1B-defective adenovirus.

Z. Oltvai, S. Korsmeyer, P. Branton, 1994, The Journal of biological chemistry.

Genome-scale identification of conditionally essential genes in E. coli by DNA microarrays.

Gábor Balázsi, Zoltán N Oltvai, J. W. Campbell, 2004, Biochemical and biophysical research communications.

Experimental Determination and System Level Analysis of Essential Genes in Escherichia coli MG1655

J. W. Campbell, J. W. Campbell, A. Barabasi, 2003, Journal of Bacteriology.

Topological basis of signal integration in the transcriptional-regulatory network of the yeast, Saccharomyces cerevisiae

Illés J. Farkas, Chakra Chennubhotla, Ivet Bahar, 2006, BMC Bioinformatics.

Concomitant attenuation of HMGCR expression and activity enhances the growth inhibitory effect of atorvastatin on TGF-β-treated epithelial cancer cells

Z. Oltvai, K. Warita, Ken-ichi Ohta, 2021, Scientific Reports.

C1 inhibitor deficiency: molecular and immunologic basis of hereditary and acquired angioedema.

Z. Oltvai, K. Tung, J. Atkinson, 1991, Laboratory investigation; a journal of technical methods and pathology.

Neonatal respiratory failure due to novel compound heterozygous mutations in the ABCA3 lipid transporter

Z. Oltvai, K. Wikenheiser-Brokamp, A. Nelson, 2020, Cold Spring Harbor molecular case studies.

Cross-species queries of large gene expression databases

Ziv Bar-Joseph, Hai-Son Le, Zoltán N. Oltvai, 2010, Bioinform..

Systems biology. Life's complexity pyramid.

Albert-László Barabási, Zoltán N Oltvai, A. Barabasi, 2002, Science.

Spurious spatial periodicity of co-expression in microarray data due to printing design.

Albert-László Barabási, Gábor Balázsi, Zoltán N Oltvai, 2003, Nucleic acids research.

Catabolic efficiency of aerobic glycolysis: The Warburg effect revisited

Yi Zhou, Zoltán N. Oltvai, Alexei Vazquez, 2010, BMC Systems Biology.

Topological units of environmental signal processing in the transcriptional regulatory network of Escherichia coli

Z. N. Oltvai, A. Barabasi, Z. Oltvai, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Bioinformatics analysis of experimentally determined protein complexes in the yeast, S. cerevisiae

A. Barabasi, Z. Oltvai, Z. Dezső, 2003, q-bio/0310012.

Saccharomyces cerevisiaeComplexes in the Yeast Bioinformatics Analysis of Experimentally Determined Protein data

A. Barabasi, Z. Oltvai, Z. Dezső, 2003 .

Statin-induced mevalonate pathway inhibition attenuates the growth of mesenchymal-like cancer cells that lack functional E-cadherin mediated cell cohesion

Z. Oltvai, A. Vazquez, A. Wells, 2014, Scientific Reports.

Statin drugs to reduce breast cancer recurrence and mortality

Z. Oltvai, A. Wells, A. Brufsky, 2018, Breast Cancer Research.

BalestraWeb: efficient online evaluation of drug–target interactions

Ivet Bahar, Zoltán N. Oltvai, D. Lansing Taylor, 2014, Bioinform..

Predicting Drug–Target Interactions Using Probabilistic Matrix Factorization

Chang Liu, Ivet Bahar, Zoltán N. Oltvai, 2013, J. Chem. Inf. Model..

Concomitant attenuation of HMG-CoA reductase expression potentiates the cancer cell growth-inhibitory effect of statins and expands their efficacy in tumor cells with epithelial characteristics

Z. Oltvai, A. Wells, K. Warita, 2018, Oncotarget.

Clonal cytopenia of undetermined significance (CCUS)-associated reversion of donor-derived, transient αβ T-cell large granular clonal lymphocytosis, emerging post-transplant in a patient with a history of γδ T-cell large granular lymphocytic leukemia

Z. Oltvai, P. Rothberg, J. Liesveld, 2023, Cold Spring Harbor molecular case studies.

Biomarker identification for statin sensitivity of cancer cell lines

Alan Wells, Zoltán N Oltvai, Vineet K Raghu, 2017, bioRxiv.

Synchronous triple thyroid neoplasms with unique molecular alterations: A rare case report

Z. Oltvai, Dongwei Zhang, Xiaoyan Liao, 2023, Human Pathology Reports.

Networks in life: Scaling properties and eigenvalue spectra

Z. Neda, I. Farkas, T. Vicsek, 2002, cond-mat/0303106.

Impact of the solvent capacity constraint on E. coli metabolism

Ziv Bar-Joseph, Albert-László Barabási, Zoltán N. Oltvai, 2008, BMC Systems Biology.

Scale‐Free and Hierarchical Structures in Complex Networks

Albert-László Barabási, Zoltán N. Oltvai, Zoltán Dezső, 2003 .

The metabolic demands of cancer cells are coupled to their size and protein synthesis rates

Z. Oltvai, A. Vazquez, J. Bertino, 2013, Cancer & metabolism.

Shaping specificity in signaling networks

Z. Oltvai, R. Albert, 2007, Nature Genetics.

Assessing acquired resistance to IDH1 inhibitor therapy by full-exon IDH1 sequencing and structural modeling

Z. Oltvai, P. Mróz, D. Koes, 2021, Cold Spring Harbor molecular case studies.

Cell-cell communication enhances bacterial chemotaxis toward external attractants

Z. Oltvai, Zhicheng Long, H. Salman, 2017, Scientific Reports.

A Pitfall in Series of Microarrays

Zoltán N. Oltvai, Gábor Balázsi, Z. Oltvai, 2007 .

Efficient Lung Cancer Molecular Diagnostics by Combining Next Generation Sequencing with Reflex Idylla Genefusion Assay Testing

Z. Oltvai, M. Velez, Huijie Liu, 2023, Genes.

Distributed Gradient Descent in Bacterial Food Search

Ziv Bar-Joseph, Shashank Singh, Saket Navlakha, 2016, RECOMB 2016.

Quantitative assessment of cell fate decision between autophagy and apoptosis

Z. Oltvai, I. Bahar, H. Bayır, 2017, Scientific Reports.

HMG-CoA reductase degrader, SR-12813, counteracts statin-induced upregulation of HMG-CoA reductase and augments the anticancer effect of atorvastatin.

Z. Oltvai, K. Warita, Takuro Ishikawa, 2023, Biochemical and biophysical research communications.

Statins attenuate outgrowth of breast cancer metastases

Z. Oltvai, A. Wells, A. Clark, 2018, British Journal of Cancer.

Predicting Drug–Target Interactions Using Probabilistic Matrix Factorization

Z. Oltvai, I. Bahar, Chang Liu, 2013, J. Chem. Inf. Model..

Clinicopathologic and Molecular Characterization of Anorectal Neuroendocrine Carcinomas Reveals Human Papillomavirus, p53 and c-Myc as Alternative Mechanisms of Carcinogenesis.

Z. Oltvai, W. Crowe, Bin Zhang, 2023, Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc.

Matching experiments across species using expression values and textual information

Ziv Bar-Joseph, Zoltán N. Oltvai, Aaron Wise, 2012, Bioinform..

Network biology: understanding the cell's functional organization

Z. Oltvai, A. Barabási, 2004, Nature Reviews Genetics.

Impact of the solvent capacity constraint on E. coli metabolism

Z. Oltvai, Z. Bar-Joseph, A. Vazquez, 2008, BMC Systems Biology.

Impact of the Solvent Capacity Constraint on E. Coli Metabolism Impact of the Solvent Capacity Constraint on E. Coli Metabolism

Z. Oltvai, A. Vazquez, A. Barabási, 2022 .

Expression of housekeeping genes varies depending on mevalonate pathway inhibition in cancer cells

Z. Oltvai, K. Warita, Yaxuan Zhou, 2023, Heliyon.

Comparative Genome-Scale Metabolic Reconstruction and Flux Balance Analysis of Multiple Staphylococcus aureus Genomes Identify Novel Antimicrobial Drug Targets

Z. Oltvai, E. Almaas, V. Kapatral, 2009, Journal of bacteriology.

Distributed Gradient Descent in Bacterial Food Search

Z. Oltvai, Z. Bar-Joseph, S. Rashid, 2016, RECOMB 2016.

Impact of the solvent capacity constraint on E. coli metabolism

Z. Oltvai, Z. Bar-Joseph, A. Vazquez, 2008, BMC Systems Biology.

A Semi-Supervised Method for Predicting Transcription Factor–Gene Interactions in Escherichia coli

Jason B. Ernst, Krin A. Kay, Z. Oltvai, 2008, PLoS Comput. Biol..

Workflow organization in pathology.

Z. Oltvai, L. Pantanowitz, A. Parwani, 2012, Clinics in laboratory medicine.