J. Nevins

J. Nevins, M. Qumsiyeh, G. Leone, 2000, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

Cellular Targets for Activation by the E2F1 Transcription Factor Include DNA Synthesis- and G1/S-Regulatory Genes

J. Nevins, T. Kowalik, J. DeGregori, 1995 .

Disruption of cell-cycle control by viral oncoproteins.

J. Nevins, 1993, Biochemical Society transactions.

Mechanism of activation of early viral transcription by the adenovirus E1A gene product

J. Nevins, 1981, Cell.

Relative position and strengths of poly(A) sites as well as transcription termination are critical to membrane versus secreted mu-chain expression during B-cell development.

J. Nevins, M. McDevitt, P. Tucker, 1987, Genes & development.

Adenovirus gene expression: Control at multiple steps of mRNA biogenesis

J. Nevins, 1982, Cell.

Distinct Gene Expression Phenotypes of Cells Lacking Rb and Rb Family Members 1,2

M. West, H. Dressman, E. Huang, 2003 .

N-6-methyl-adenosine in adenovirus type 2 nuclear RNA is conserved in the formation of messenger RNA.

J. Nevins, J. Darnell, S. Chen‐Kiang, 1979, Journal of molecular biology.

Evidence from UV transcription mapping that late adenovirus type 2 mRNA is derived from a large precursor molecule

J. Nevins, J. Darnell, S. Goldberg, 1978, Journal of virology.

Groups of adenovirus type 2 mRNA's derived from a large primary transcript: probable nuclear origin and possible common 3' ends

J. Nevins, J. Darnell, 1978, Journal of Virology.

Retraction. Potti A, Bild A, Dressman HK, Lewis DA, Nevins JR, Ortel TL. Gene-expression patterns predict phenotypes of immune-mediated thrombosis. Blood. 2006;107(4):1391-1396.

H. Dressman, J. Nevins, A. Bild, 2011, Blood.

Alternative poly(A) site utilization during adenovirus infection coincides with a decrease in the activity of a poly(A) site processing factor

J. Nevins, E. Weiss, K. Mann, 1993, Molecular and cellular biology.

Poly(A) site cleavage in a HeLa nuclear extract is dependent on downstream sequences

J. Nevins, M. McDevitt, R. Hart, 1985, Cell.

Definition of essential sequences and functional equivalence of elements downstream of the adenovirus E2A and the early simian virus 40 polyadenylation sites

J. Nevins, M. McDevitt, R. Hart, 1985, Molecular and cellular biology.

THE ROLE OF POLY(A) IN MAMMALIAN GENE EXPRESSION11This work was supported by grants from the National Institutes of Health (CA 16006-09) and the American Cancer Society (CD 123).

J. Nevins, J. Darnell, M. Zeevi, 1982 .

Newly formed mRNA lacking polyadenylic acid enters the cytoplasm and the polyribosomes but has a shorter half-life in the absence of polyadenylic acid

J. Nevins, J. Darnell, M. Zeevi, 1982, Molecular and cellular biology.

Processing of late adenovirus nuclear RNA to mRNA. Kinetics of formation of intermediates and demonstration that all events are nuclear.

J. Nevins, 1979, Journal of molecular biology.

The major late adenovirus type-2 transcription unit: termination is downstream from the last poly(A) site.

J. Nevins, J. Darnell, E. Ziff, 1979, Journal of molecular biology.

Metabolism of mRNA from the transforming region of adenovirus 2.

J. Nevins, J. Darnell, J. Blanchard, 1980, Cold Spring Harbor symposia on quantitative biology.

Transcription units of adenovirus type 2. Termination of transcription beyond the poly(A) addition site in early regions 2 and 4.

J. Nevins, J. Darnell, J. Blanchard, 1980, Journal of molecular biology.

Identification of distinct roles for separate E1A domains in disruption of E2F complexes

J. Nevins, M. Ikeda, M. Ikeda, 1993, Molecular and cellular biology.

Regulation of the Primary Expression of the Early Adenovirus Transcription Units

J. Nevins, J. Darnell, J. Blanchard, 1979, Journal of virology.

Identification of a Novel E2F3 Product Suggests a Mechanism for Determining Specificity of Repression by Rb Proteins

J. Nevins, R. Sears, S. Ishida, 2000, Molecular and Cellular Biology.

Complex Transcriptional Regulatory Mechanisms Control Expression of the E2F3 Locus

J. Nevins, R. Sears, G. Leone, 2000, Molecular and Cellular Biology.

Selective induction of E2F1 in response to DNA damage, mediated by ATM-dependent phosphorylation.

J. Nevins, W. Lin, F. Lin, 2001, Genes & development.

Localization of the adenovirus E1Aa protein, a positive-acting transcriptional factor, in infected cells infected cells

J. Nevins, L. Feldman, 1983, Molecular and cellular biology.

Genomic analysis of response to lactic acidosis in human cancers

M. West, J. Nevins, M. Dewhirst, 2008 .

Collaborative role of E2F transcriptional activity and G1 cyclindependent kinase activity in the induction of S phase.

J. Nevins, J. Cook, G. Leone, 1999, Proceedings of the National Academy of Sciences of the United States of America.

The adenovirus-inducible factor E2F stimulates transcription after specific DNA binding

J. Nevins, P. Raychaudhuri, L. Jakoi, 1989, Molecular and cellular biology.

Adenovirus E1A-mediated negative control of genes activated during F9 differentiation

J. Nevins, R. Weigel, S. Hiebert, 1989, Molecular and cellular biology.

A factor discriminating between the wildtype and a mutant polyomavirus enhancer

J. Nevins, Yoshiaki Ito, I. Kovesdi, 1987, Nature.

A genetic analysis of the E2F1 gene distinguishes regulation by Rb, p107, and adenovirus E4

J. Nevins, W. D. Cress, D. Johnson, 1993 .

Promoter-specific trans-activation by the adenovirus E1A12S product involves separate E1A domains

J. Nevins, E. Moran, V. Kraus, 1992, Molecular and cellular biology.

DNA octamer element can confer E1A trans-activation, and adenovirus infection results in a stimulation of the DNA-binding activity of OTF-1/NFIII factor.

J. Nevins, S. Chellappan, 1990, Proceedings of the National Academy of Sciences of the United States of America.

E1A-dependent trans-activation of the c-fos promoter requires the TATAA sequence.

J. Nevins, N. Heintz, M. Simon, 1990, Proceedings of the National Academy of Sciences of the United States of America.

The hsp7O Gene CCAAT-Binding Factor Mediates Transcriptional Activation by the Adenovirus Ela Protein

J. Nevins, T. Mcclanahan, H. Kao, 2022 .

Identification of an E1A‐inducible cellular factor that interacts with regulatory sequences within the adenovirus E4 promoter.

J. Nevins, P. Raychaudhuri, R. Rooney, 1987, The EMBO journal.

Detection of an adenovirus E1A-like activity in mammalian cells.

J. Nevins, H. Kao, M. Imperiale, 1984, Current topics in microbiology and immunology.

Regulation of early adenovirus gene expression.

J. Nevins, Joseph R. NEVINSt, 1987, Microbiological reviews.

Alteration of cellular gene expression in adenovirus transformed cells by post-transcriptional mechanisms.

J. Nevins, H. Kao, 1986, Nucleic acids research.

Adenovirus 5E2Transcription Unit: an ElA-Inducible Promoter with an Essential Element ThatFunctions Independently ofPosition

J. Nevins, M. Imperiale, 1984 .

Activation of a preexisting cellular factor as a basis for adenovirus E1A-mediated transcription control.

J. Nevins, I. Kovesdi, R. Reichel, 1988, Proceedings of the National Academy of Sciences of the United States of America.

Transcription activation by viral and cellular oncogenes.

J. Nevins, 1986, Advances in cancer research.

Interactions of the p107 and Rb proteins with E2F during the cell proliferation response.

J. Nevins, S. Chellappan, L. Jakoi, 1993, The EMBO journal.

Promoter interaction of the E1A‐inducible factor E2F and its potential role in the formation of a multi‐component complex.

J. Nevins, A. Yee, I. Kovesdi, 1987, The EMBO journal.

Essential Element That Functions Independently of Position

J. Nevins, M. Imperiale, 2022 .

Interaction of YY1 with E2Fs, mediated by RYBP, provides a mechanism for specificity of E2F function

J. Nevins, M. Vidal, Joseph R Nevins, 2002, The EMBO journal.

Evaluation on star tree simulation data Supplementary material for Alignment Tool Evaluation

J. Nevins, U. Ohler, Weichun Huang, 2007 .

J. Nevins, E. J. Smith, 1995, Molecular and cellular biology.

Poly(A) site choice rather than splice site choice governs the regulated production of IgM heavy-chain RNAs.

J. Nevins, P. Tucker, J. Guise, 1988, Proceedings of the National Academy of Sciences of the United States of America.

Addition of poly(A) to nuclear RNA occurs soon after RNA synthesis

J. Nevins, J. Darnell, S. Sawicki, 1980, Journal of Cell Biology.

An integrated genomic-based approach to individualized treatment of patients with advanced-stage ovarian cancer (Journal of Clinical Oncology (2007) 25 (517-525))

M. West, H. Dressman, J. Nevins, 2012 .

Sensing and Integration of Erk and PI3K Signals by Myc

Guang Yao, Joseph Nevins, Lingchong You, 2008, PLoS Comput. Biol..

E2F1 overexpression in quiescent fibroblasts leads to induction of cellular DNA synthesis and apoptosis

J. Nevins, T. Kowalik, J. DeGregori, 1995, Journal of virology.

Adenovirus E1A, simian virus 40 tumor antigen, and human papillomavirus E7 protein share the capacity to disrupt the interaction between transcription factor E2F and the retinoblastoma gene product.

J. Nevins, P. Howley, K. Munger, 1992, Proceedings of the National Academy of Sciences of the United States of America.

DNA-binding activity of the adenovirus-induced E4F transcription factor is regulated by phosphorylation.

J. Nevins, P. Raychaudhuri, S. Bagchi, 1989, Genes & development.

Activation of early adenovirus transcription by the herpesvirus immediate early gene: evidence for a common cellular control factor.

J. Nevins, M. Imperiale, L. Feldman, 1982, Proceedings of the National Academy of Sciences of the United States of America.

Induction of the synthesis of a 70,000 dalton mammalian heat shock protein by the adenovirus E1A gene product

J. Nevins, 1982, Cell.

The pathway of eukaryotic mRNA formation.

J. Nevins, 1983, Annual review of biochemistry.

Mechanisms of viral-mediated trans-activation of transcription.

J. Nevins, 1989, Advances in virus research.

Nuclear RNA is spliced in the absence of poly(A) addition

J. Nevins, J. Darnell, M. Zeevi, 1981, Cell.

Role of an adenovirus E2 promoter binding factor in E1A-mediated coordinate gene control.

J. Nevins, I. Kovesdi, R. Reichel, 1987, Proceedings of the National Academy of Sciences of the United States of America.

Identification of a cellular transcription factor involved in E1A trans-activation

J. Nevins, I. Kovesdi, R. Reichel, 1986, Cell.

An enhancer-like element in the adenovirus E2 promoter contains sequences essential for uninduced and E1A-induced transcription.

J. Nevins, M. Imperiale, R. Hart, 1985, Proceedings of the National Academy of Sciences of the United States of America.

Isolation and partial characterization of the poly(A) polymerases from HeLa cells infected with vaccinia virus.

J. Nevins, W. Joklik, 1977, The Journal of biological chemistry.

An ordered pathway of assembly of components required for polyadenylation site recognition and processing.

J. Nevins, G. Gilmartin, 1989, Genes & development.

A Genomic Approach to Improve Prognosis and Predict Therapeutic Response in Chronic Lymphocytic Leukemia

Anil Potti, William T Barry, J. Nevins, 2009, Clinical Cancer Research.

Genetic heterogeneity of Myc-induced mammary tumors reflecting diverse phenotypes including metastatic potential

Jeffrey T. Chang, Michael L. Gatza, J. Nevins, 2009, Proceedings of the National Academy of Sciences.

The E2F1–3 transcription factors are essential for cellular proliferation

J. Nevins, M. Greenberg, S. Orkin, 2001, Nature.

E1A-dependent trans-activation of the human MYC promoter is mediated by the E2F factor.

M Lipp, J. Nevins, S. Hiebert, 1989, Proceedings of the National Academy of Sciences of the United States of America.

Author Correction: Division of labour between Myc and G1 cyclins in cell cycle commitment and pace control

J. Nevins, L. You, B. Mathey-Prevot, 2018, Nature Communications.

Division of labour between Myc and G1 cyclins in cell cycle commitment and pace control

J. Nevins, L. You, B. Mathey-Prevot, 2014, Nature Communications.

Gene Expression Signatures of Radiation Response Are Specific, Durable and Accurate in Mice and Humans

Joseph R. Nevins, H. Dressman, J. Nevins, 2008, PloS one.

Refocusing the War on Cancer: The Critical Role of Personalized Treatment

J. Nevins, R. Schilsky, A. Potti, 2010, Science Translational Medicine.

Insight into mammary gland development and tumor prevention in a newly developed metastatic mouse model of breast cancer

J. Nevins, E. Andrechek, Shams Reaz, 2021, bioRxiv.

A signalling pathway controlling c-Myc degradation that impacts oncogenic transformation of human cells

Joseph R. Nevins, William C. Hahn, P. Todd Stukenberg, 2004, Nature Cell Biology.

Retraction for Garman et al., A genomic approach to colon cancer risk stratification yields biologic insights into therapeutic opportunities

J. Nevins, Sayan Mukherjee, G. Ginsburg, 2011, Proceedings of the National Academy of Sciences.

A genomic approach to colon cancer risk stratification yields biologic insights into therapeutic opportunities

Elena Edelman, Jochen Gaedcke, Anil Potti, 2008, Proceedings of the National Academy of Sciences.

A role for E2F6 in distinguishing G1/S- and G2/M-specific transcription.

Seiichi Mori, Paloma H Giangrande, J. Nevins, 2004, Genes & development.

GATHER: a systems approach to interpreting genomic signatures

Jeffrey T. Chang, Joseph Nevins, J. Nevins, 2006, Bioinform..

Gene Expression Patterns That Characterize Advanced Stage Serous Ovarian Cancers

Jeffrey R Marks, H. Dressman, J. Nevins, 2004, The Journal of the Society for Gynecologic Investigation: JSGI.

Identification of positively and negatively acting elements regulating expression of the E2F2 gene in response to cell growth signals

J. Nevins, R. Sears, K. Ohtani, 1997, Molecular and cellular biology.

Using noisy gene expression mediated by engineered adenovirus to probe signaling dynamics in mammalian cells.

J. Nevins, Guang Yao, L. You, 2011, Methods in enzymology.

A Role for E2F Activities in Determining the Fate of Myc-Induced Lymphomagenesis

J. Nevins, S. Mori, M. Gasparetto, 2009, PLoS genetics.

A role for Myc in facilitating transcription activation by E2F1

J. Nevins, P. Giangrande, G. L. Ehmann, 2008, Oncogene.

The Rb / E 2 F pathway and cancer

J. Nevins, 2001 .

Balancing the decision of cell proliferation and cell fate

J. Nevins, T. Hallstrom, Joseph R Nevins, 2009, Cell cycle.

Specificity in the activation and control of transcription factor E2F-dependent apoptosis

J. Nevins, T. Hallstrom, Timothy C. Hallstrom, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Interacting domains of E2F1, DP1, and the adenovirus E4 protein

J. Nevins, W. D. Cress, W. Cress, 1994, Journal of virology.

Transactivation by the adenovirus E1A gene.

J. Nevins, P. Raychaudhuri, A. Yee, 1988, Biochemistry and cell biology = Biochimie et biologie cellulaire.

Temporal Control of Cell Cycle Gene Expression Mediated by E2F Transcription Factors

J. Nevins, P. Giangrande, Wencheng Zhu, 2005, Cell cycle.

Interaction of E2F7 Transcription Factor with E2F1 and C-terminal-binding Protein (CtBP) Provides a Mechanism for E2F7-dependent Transcription Repression*

J. Nevins, M. Gatza, I. Shats, 2013, The Journal of Biological Chemistry.

Developmental control of a promoter-specific factor that is also regulated by the E1A gene product

J. Nevins, I. Kovesdi, R. Reichel, 1987, Cell.

E2F6 Associates with BRG1 in Transcriptional Regulation

J. Nevins, J. Leung, 2012, PloS one.

Steps in the processing of Ad2 mRNA: Poly(A)+ Nuclear sequences are conserved and poly(A) addition precedes splicing

J. Nevins, J. Darnell, 1978, Cell.

Poly(A) site efficiency reflects the stability of complex formation involving the downstream element.

J. Nevins, G. Gilmartin, E. Weiss, 1991, The EMBO journal.

SIGNATURE: A workbench for gene expression signature analysis

William T. Barry, Joseph E. Lucas, Jeffrey T. Chang, 2011, BMC Bioinformatics.

E2Fs link the control of G1/S and G2/M transcription

J. Nevins, P. Giangrande, Wencheng Zhu, 2004, The EMBO journal.

FOXO transcription factors control E2F1 transcriptional specificity and apoptotic function.

Michael L. Gatza, Steven P. Angus, J. Nevins, 2013, Cancer research.

Multiple factors are required for poly(A) addition to a mRNA 3' end.

J. Nevins, M. McDevitt, G. Gilmartin, 1988, Genes & development.

E2F1-Mediated Induction of NFYB Attenuates Apoptosis via Joint Regulation of a Pro-Survival Transcriptional Program

J. Nevins, J. Chi, I. Shats, 2015, PloS one.

Prediction of optimal versus suboptimal cytoreduction of advanced-stage serous ovarian cancer with the use of microarrays.

M. West, H. Dressman, J. Nevins, 2004, American journal of obstetrics and gynecology.

Distinct DNA targets for trans-activation by HTLV-1 tax and adenovirus E1A.

J. Nevins, J. Nicholas, 1991, Virology.

Utilization of the Eμ-Myc Mouse to Model Heterogeneity of Therapeutic Response

J. Nevins, T. Tan, S. Mori, 2014, Molecular Cancer Therapeutics.

Companion Diagnostics and Cancer Biomarkers Utilization of the E l-Myc Mouse to Model Heterogeneity of Therapeutic Response

J. Nevins, T. Tan, S. Mori, 2014 .

Title : Utilization of the E μ-Myc Mouse to Model Heterogeneity of Therapeutic Response Running Title : Mouse model of human lymphoma therapy heterogeneity

J. Nevins, T. Tan, S. Mori, 2014 .

Combinatorial gene control involving E2F and E Box family members

J. Nevins, P. Giangrande, R. Rempel, 2004, The EMBO journal.

Identification of E-Box Factor TFE3 as a Functional Partner for the E2F3 Transcription Factor

Joseph R. Nevins, Paloma H. Giangrande, J. Nevins, 2003, Molecular and Cellular Biology.

Loss of E2F4 activity leads to abnormal development of multiple cellular lineages.

Seiichi Ishida, J. Nevins, J. Pipas, 2000, Molecular cell.

A role for a bent DNA structure in E2F-mediated transcription activation

J. Nevins, W. D. Cress, W. Cress, 1996, Molecular and cellular biology.

Compensation and specificity of function within the E2F family

J. Nevins, A. Bild, J. T. Chang, 2007, Oncogene.

Myc-induced microRNAs integrate Myc-mediated cell proliferation and cell fate.

J. Nevins, S. Mori, Jong Wook Kim, 2010, Cancer research.

Control of cellular and viral transcription during adenovirus infection.

J. Nevins, 1986, CRC critical reviews in biochemistry.

Regulation of early adenovirus transcription: a protein product of early region 2 specifically represses region 4 transcription.

J. Nevins, J. Winkler, 1980, Proceedings of the National Academy of Sciences of the United States of America.

Activation of gene expression by adenovirus and herpesvirus regulatory genes acting in trans and by a cis-acting adenovirus enhancer element

J. Nevins, M. Imperiale, L. Feldman, 1983, Cell.

The HTLV-I rex response element mediates a novel form of mRNA polyadenylation

Joseph R. Nevins, J. Nevins, W. Greene, 1991, Cell.

Utilization of pathway signatures to reveal distinct types of B lymphoma in the Emicro-myc model and human diffuse large B-cell lymphoma.

Jeffrey T. Chang, J. Nevins, Guang Yao, 2008, Cancer research.

Definition of multiple, functionally distinct TATA elements, one of which is a target in the hsp70 promoter for E1A regulation

J. Nevins, N. Heintz, M. Simon, 1988, Cell.

A genomic approach to identify molecular pathways associated with chemotherapy resistance

Anil Potti, Bala Balakumaran, Joseph Nevins, 2008, Molecular Cancer Therapeutics.

Distinct mechanisms control the accumulation of the Rb-related p107 and p130 proteins during cell growth.

J. Nevins, G. Leone, E. J. Smith, 1998, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

Retraction: A genomic strategy to refine prognosis in early-stage non-small-cell lung cancer. N Engl J Med 2006;355:570-80.

S. Mukherjee, M. West, H. Dressman, 2011, The New England journal of medicine.

Retraction. Pharmacogenomic strategies provide a rational approach to the treatment of cisplatin-resistant patients with advanced cancer. J Clin Oncol 25:4350–7, 2007.

H. Dressman, J. Nevins, P. Febbo, 2010, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

A randomized phase II trial evaluating the performance of genomic expression profiles to direct the use of preoperative chemotherapy for early-stage breast cancer.

J. Olson, J. Nevins, G. Ginsburg, 2010 .

Corrigendum: Genomic signatures to guide the use of chemotherapeutics

H. Dressman, J. Nevins, P. Febbo, 2008 .

Bayesian analysis of binary prediction tree models for retrospectively sampled outcomes.

Mike West, Quanli Wang, Joseph Nevins, 2004, Biostatistics.

Using a stem cell-based signature to guide therapeutic selection in cancer.

Igor Shats, Jeffrey T. Chang, Michael L. Gatza, 2011, Cancer research.

The interaction of RB with E2F coincides with an inhibition of the transcriptional activity of E2F.

J. Nevins, S. Chellappan, S. Chellappan, 1992, Genes & development.

Huntingtin Is Present in the Nucleus, Interacts with the Transcriptional Corepressor C-terminal Binding Protein, and Represses Transcription*

J. Nevins, Z. Qin, N. Aronin, 2002, The Journal of Biological Chemistry.

Utilization of genomic signatures to direct use of primary chemotherapy.

J. Nevins, A. Potti, 2008, Current opinion in genetics & development.

An E2F1-dependent gene expression program that determines the balance between proliferation and cell death.

Seiichi Mori, J. Nevins, S. Mori, 2008, Cancer cell.

Adenovirus E1A proteins can dissociate heteromeric complexes involving the E2F transcription factor: A novel mechanism for E1A trans-activation

J. Nevins, P. Raychaudhuri, S. Bagchi, 1990, Cell.

Gene expression profiles of tumor biology provide a novel approach to prognosis and may guide the selection of therapeutic targets in multiple myeloma.

J. Nevins, F. Zhan, B. Barlogie, 2009, Journal of Clinical Oncology.

Mouse models of cancers: opportunities to address heterogeneity of human cancer and evaluate therapeutic strategies

J. Nevins, E. Andrechek, 2010, Journal of Molecular Medicine.

Gene Expression Profiles of Multiple Breast Cancer Phenotypes and Response to Neoadjuvant Chemotherapy

Andrea Bild, Mike West, Zeljko Vujaskovic, 2006, Clinical Cancer Research.

Functional analysis of E2F transcription factor.

J. Nevins, G. Leone, J. DeGregori, 1997, Methods in enzymology.

Gene expression phenotypic models that predict the activity of oncogenic pathways

M. West, H. Dressman, E. Huang, 2003, Nature Genetics.

Stochastic E2F Activation and Reconciliation of Phenomenological Cell-Cycle Models

Joseph R. Nevins, Lingchong You, Tae J. Lee, 2010, PLoS biology.

Adenovirus 5 E2 transcription unit: an E1A-inducible promoter with an essential element that functions independently of position or orientation

J. Nevins, M. Imperiale, 1984, Molecular and cellular biology.

Isolation and properties of the vaccinia virus DNA-dependent RNA polymerase.

J. Nevins, W. Joklik, 1977, The Journal of biological chemistry.

Genomic strategies for personalized cancer therapy.

Anil Potti, J. Nevins, A. Potti, 2007, Human molecular genetics.

Sequences capable of restoring poly(A) site function define two distinct downstream elements.

R P Hart, J. Nevins, M. McDevitt, 1986, The EMBO journal.

Molecular evidence for arterial repair in atherosclerosis.

M. West, J. Nevins, E. Herderick, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Addition of poly(A) to nuclear RNA occurs soon after RNA synthesis

J. Nevins, J. Darnell, S. Sawicki, 1980, The Journal of cell biology.

Towards integrated clinico-genomic models for personalized medicine: combining gene expression signatures and clinical factors in breast cancer outcomes prediction.

Holly Dressman, Mike West, Jennifer Pittman, 2003, Human molecular genetics.

Role of the Rb/E2F pathway in cell growth control

J. Nevins, J. DeGregori, L. Jakoi, 1997, Journal of cellular physiology.

Sparse Statistical Modelling in Gene Expression Genomics

Carlos M. Carvalho, Quanli Wang, Andrea Bild, 2006 .

An Integrated Approach to the Prediction of Chemotherapeutic Response in Patients with Breast Cancer

Anil Potti, Sayan Mukherjee, Joseph R. Nevins, 2008, PloS one.

Novel tumor sampling strategies to enable microarray gene expression signatures in breast cancer: a study to determine feasibility and reproducibility in the context of clinical care

H. Dressman, J. Olson, J. Nevins, 2009, Breast Cancer Research and Treatment.

Adenovirus E1A: transcription regulation and alteration of cell growth control.

J. Nevins, 1995, Current topics in microbiology and immunology.

Domains of the adenovirus E1A protein required for oncogenic activity are also required for dissociation of E2F transcription factor complexes.

J. Nevins, E. Moran, P. Raychaudhuri, 1991, Genes & development.

Activation of the E2F transcription factor in adenovirus-infected cells involves E1A-dependent stimulation of DNA-binding activity and induction of cooperative binding mediated by an E4 gene product

J. Nevins, P. Raychaudhuri, S. D. Neill, 1990, Journal of virology.

An adenovirus E4 gene product trans-activates E2 transcription and stimulates stable E2F binding through a direct association with E2F.

J. Nevins, A. Virtanen, S. D. Neill, 1990, Proceedings of the National Academy of Sciences of the United States of America.

The adenovirus E4 gene, in addition to the E1A gene, is important for trans-activation of E2 transcription and for E2F activation

J. Nevins, P. Raychaudhuri, I. Kovesdi, 1989, Journal of virology.

Distinctions in the specificity of E2F function revealed by gene expression signatures.

Mike West, M. West, H. Dressman, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Genomic prediction of locoregional recurrence after mastectomy in breast cancer.

M. West, H. Dressman, E. Huang, 2006, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Phosphorylation-dependent activation of the adenovirus-inducible E2F transcription factor in a cell-free system.

J. Nevins, P. Raychaudhuri, S. Bagchi, 1989, Proceedings of the National Academy of Sciences of the United States of America.

Evolving strategies for targeted cancer therapy--past, present, and future.

J. Nevins, S. Wells, 2004, Journal of the National Cancer Institute.

A Combinatorial Mechanism for Determining the Specificity of E2F Activation and Repression

Jeffrey T. Chang, J. Nevins, L. Jakoi, 2009, Oncogene.

Transcriptional activation by viral regulatory proteins.

J. Nevins, 1991, TIBS -Trends in Biochemical Sciences. Regular ed.

Characterizing the developmental pathways TTF-1, NKX2–8, and PAX9 in lung cancer

H. Dressman, J. Nevins, Sayan Mukherjee, 2009, Proceedings of the National Academy of Sciences.

ABCA1 single nucleotide polymorphisms. Snipping at the pathogenesis of atherosclerosis.

J. Nevins, P. Goldschmidt-Clermont, C. Dong, 2001, Circulation research.

Snipping at the Pathogenesis of Atherosclerosis

J. Nevins, P. Goldschmidt-Clermont, Chunming Dong, 2001 .

Transcriptional activation by the adenovirus E1A proteins

J. Nevins, 1993 .

Activation of the E 2 F Transcription Factor in Adenovirus-Infected Cells Involves ElA-Dependent Stimulation of DNA-Binding Activity and Induction of Cooperative Binding Mediated by an E 4 Gene Product

J. Nevins, P. Raychaudhuri, S. D. Neill, 2022 .

Adenovirus E1A-dependent trans-activation of transcription.

J. Nevins, 1990, Seminars in cancer biology.

Utilization of cellular transcription factors for adenovirus-induced transcription.

J. Nevins, 1991, Virus research.

Genetic analysis of the adenovirus E4 6/7 trans activator: interaction with E2F and induction of a stable DNA-protein complex are critical for activity

J. Nevins, S. D. Neill, 1991, Journal of virology.

Gene Expression Profiles ofMultiple Breast Cancer Phenotypes and Response to Neoadjuvant Chemotherapy

H. Dressman, J. Olson, J. Nevins, 2006 .

Peripheral Blood Signatures of Lead Exposure

J. Nevins, J. Chute, Heather Labreche, 2011, PloS one.

Distinct roles of E2F proteins in vascular smooth muscle cell proliferation and intimal hyperplasia

J. Nevins, B. Sullenger, P. Giangrande, 2007, Proceedings of the National Academy of Sciences.

Gene-expression patterns predict phenotypes of immune-mediated thrombosis.

Anil Potti, Andrea Bild, H. Dressman, 2006, Blood.

Use of gene expression and pathway signatures to characterize the complexity of human melanoma.

J. Nevins, C. Augustine, D. Tyler, 2011, The American journal of pathology.

The definition of transcription units for mRNA.

J. Nevins, J. Darnell, E. Ziff, 1978, Cold Spring Harbor symposia on quantitative biology.

Interaction of the Dr1 inhibitory factor with the TATA binding protein is disrupted by adenovirus E1A.

J. Nevins, D. Reinberg, J. Inostroza, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Pathway-based classification of lung cancer: a strategy to guide therapeutic selection.

J. Nevins, 2011, Proceedings of the American Thoracic Society.

Inhibition of cell proliferation by an RNA ligand that selectively blocks E2F function

J. Nevins, B. Sullenger, J. Ishizaki, 1996, Nature Medicine.

Gene expression profiling for prediction of clinical characteristics of breast cancer.

Mike West, Erich Huang, M. West, 2003, Recent progress in hormone research.

Cell Cycle Targets of Viral Oncoproteins

J. Nevins, 1994 .

Author Correction: Division of labour between Myc and G1 cyclins in cell cycle commitment and pace control

J. Nevins, L. You, B. Mathey-Prevot, 2018, Nature Communications.

Isolation and analysis of nuclear RNA.

J. Nevins, 1987, Methods in enzymology.

Stem Cells of Aging Donors—Insufficient Capacity to Repair Causes Progression of Atherosclerosis in the Recipient Molecular Evidence for Arterial Repair in Atherosclerosis. Proc Natl Acad Sci U S A 102: 16789-16794, 2005

M. West, J. Nevins, E. Herderick, 2006 .

A methodology for utilization of predictive genomic signatures in FFPE samples

H. Dressman, J. Nevins, W. Barry, 2011, BMC Medical Genomics.

The interaction of RB with E 2 F coincides with an inhibition of the transcriptional activity of E 2 F

J. Nevins, S. Hiebert, J. Horowitz, 2007 .

E2F transcription factor is a target for the RB protein and the cyclin A protein.

J. Nevins, T. Hunter, S. Chellappan, 1991, Cold Spring Harbor symposia on quantitative biology.

In silico prediction of transcription factors that interact with the E2F family of transcription factors

Qing Zhou, Sheng Zhong, Wing Hung Wong, 2004, ICARCV 2004 8th Control, Automation, Robotics and Vision Conference, 2004..

Reply to 'Microarrays: retracing steps'

J. Nevins, A. Potti, 2007, Nature Medicine.

Prediction and uncertainty in the analysis of gene expression profiles

Mike West, Rainer Spang, Joseph Nevins, 2002, Silico Biol..

An integrated approach to the prediction of chemotherapeutic response in patients with breast cancer.

H. Dressman, J. Olson, J. Nevins, 2008, PLoS ONE.

Adenovirus infection of differentiated F9 cells results in a global shut-off of differentiation-induced gene expression.

J. Nevins, R. Weigel, 1990, Nucleic acids research.

DNA Microarray Data Analysis and Regression Modeling for Genetic Expression Profiling

Rainer Spang, Jeffrey R. Marks, Joseph R. Nevins, 2000 .

Using a stem cell-based signature to guide therapeutic selection in cancer.

Jeffrey T. Chang, Michael L. Gatza, J. Nevins, 2011, Cancer research.

Patterns of cell signaling pathway activation that characterize mammary development

Jeffrey T. Chang, J. Nevins, S. Mori, 2008, Development.

A genomic strategy to elucidate modules of oncogenic pathway signaling networks.

Jeffrey T. Chang, Michael L. Gatza, M. West, 2009, Molecular cell.

Utilization of pathway signatures to reveal distinct types of B lymphoma in the Emicro-myc model and human diffuse large B-cell lymphoma.

Jeffrey T. Chang, J. Nevins, Guang Yao, 2008, Cancer research.