B. Strulovici

发表

Genome-scale RNAi screen for host factors required for HIV replication.

Amy S. Espeseth, Honglin Zhou, Min Xu, 2008, Cell host & microbe.

Induced pluripotent stem cells — opportunities for disease modelling and drug discovery

B. Strulovici, G. Daley, A. Javaherian, 2011, Nature Reviews Drug Discovery.

Miniaturization of Intracellular Calcium Functional Assays to 1536-Well Plate Format Using a Fluorometric Imaging Plate Reader

B. Strulovici, P. Hodder, R. Mull, 2004, Journal of biomolecular screening.

Median Absolute Deviation to Improve Hit Selection for Genome-Scale RNAi Screens

Marc Ferrer, Berta Strulovici, Peter S Linsley, 2008, Journal of biomolecular screening.

Application of real-time cell electronic sensing (RT-CES) technology to cell-based assays.

Wei Zheng, Berta Strulovici, Kelli Solly, 2004, Assay and drug development technologies.

Miniaturization of Whole Live Cell-Based GPCR Assays Using Microdispensing and Detection Systems

James Inglese, Oleg Kornienko, Berta Strulovici, 2004, Journal of biomolecular screening.

Miniaturization of a hepatitis C virus RNA polymerase assay using a -102 degrees C cooled CCD camera-based imaging system.

B. Strulovici, James Inglese, L. Howells, 2001, Analytical biochemistry.

Identification of metabotropic glutamate receptor antagonists using an automated high-throughput screening system.

B. Strulovici, C. Bayly, James Inglese, 2003, Analytical biochemistry.

Compounds that bind APP and inhibit Abeta processing in vitro suggest a novel approach to Alzheimer disease therapeutics.

Amy S. Espeseth, Min Xu, Qian Huang, 2005, The Journal of biological chemistry.

A high-precision fluorogenic cholesteryl ester transfer protein assay compatible with animal serum and 3456-well assay technology.

Gregory T O'Donnell, M. Ferrer, B. Strulovici, 2007, Analytical biochemistry.

Ultra-high-throughput screening for antagonists of a Gi-coupled receptor in a 2.2-microl 3,456-well plate format cyclicAMP assay.

Oleg Kornienko, Berta Strulovici, Lalitha Muthusubramaniam, 2007, Assay and drug development technologies.

A 1,536-well [(35)S]GTPgammaS scintillation proximity binding assay for ultra-high-throughput screening of an orphan galphai-coupled GPCR.

M. Ferrer, B. Strulovici, P. Kunapuli, 2008, Assay and drug development technologies.

Constitutive presence of a catalytic fragment of protein kinase C epsilon in a small cell lung carcinoma cell line.

B. Strulovici, S. Daniel-Issakani, G. Baxter, 1992, The Journal of biological chemistry.

High-throughput screening of 11beta-hydroxysteroid dehydrogenase type 1 in scintillation proximity assay format.

B. Strulovici, Wei Zheng, K. Solly, 2005, Assay and drug development technologies.

Penazetidine A, an alkaloid inhibitor of protein kinase C

B. Strulovici, M. Jaspars, P. Crews, 1994 .

Characterization of Protein Kinase C Isoforms in a Small Cell Lung Carcinoma Cell Line: Regulation of PKCε and its Catalytic Fragment

B. Strulovici, G. Baxter, 1991 .

An automated high throughput filtration assay: application to polymerase inhibitor identification.

B. Strulovici, S. Daniel-Issakani, K. Lamarco, 1997, Analytical biochemistry.

Desensitization of the beta-adrenergic receptor of frog erythrocytes. Recovery and characterization of the down-regulated receptors in sequestered vesicles.

B. Strulovici, M. Caron, R. Lefkowitz, 1983, The Journal of biological chemistry.

Direct demonstration of impaired functionality of a purified desensitized beta-adrenergic receptor in a reconstituted system.

B. Strulovici, M. Caron, R. Lefkowitz, 1984, Science.

Differential expression of protein kinase C epsilon protein in lung cancer cell lines by ionising radiation.

B. Strulovici, A. Giaccia, J. Brown, 1992, British Journal of Cancer.

Stimulation by cyclic GMP of prostaglandin E production in isolated Graafian follicles.

B. Strulovici, U. Zor, H. R. Lindner, 1977, Biochemical and biophysical research communications.

Adenylate-Cyclase-Coupled β- Adrenergic Receptors

B. Strulovici, R. Lefkowitz, J. Stadel, 1985 .

A miniaturized cell-based fluorescence resonance energy transfer assay for insulin-receptor activation.

Shane D. Marine, Erica M. Stec, M. Ferrer, 2006, Analytical biochemistry.

A chemiluminescent microtiter plate assay for sensitive detection of protein kinase activity.

B. Strulovici, S. Daniel-Issakani, C. Lehel, 1997, Analytical biochemistry.

Differential regulation of protein kinase C isoforms in isolated neonatal and adult rat cardiomyocytes.

B. Strulovici, L. Brunton, M. Pucéat, 1994, The Journal of biological chemistry.

A fluorescence-based thiol quantification assay for ultra-high-throughput screening for inhibitors of coenzyme A production.

Erica M. Stec, M. Ferrer, B. Strulovici, 2008, Assay and drug development technologies.

Identification of small molecule antagonists of the human mas-related gene-X1 receptor.

B. Strulovici, M. Simon, Wei Zheng, 2006, Analytical biochemistry.

Transmembrane signaling by interferon

B. Strulovici, L. Pfeffer, B. Eisenkraft, 2022 .

A Multiplexed siRNA Screening Strategy to Identify Genes in the PARP Pathway

Erica M. Stec, M. Ferrer, B. Strulovici, 2012, Journal of biomolecular screening.

Miniaturizable homogenous time-resolved fluorescence assay for carboxypeptidase B activity.

M. Ferrer, B. Strulovici, James Inglese, 2003, Analytical biochemistry.

Purification, characterization and reconstitution of the adenylate cyclase-coupled β-adrenergic receptor

B. Strulovici, M. Caron, G. Stiles, 1984 .

Functional integrity of desensitized beta-adrenergic receptors.

B. Strulovici, R. Lefkowitz, J. Stadel, 1983, The Journal of biological chemistry.

Phosphorylation substrates for protein kinase C in intact pituitary cells: characterization of a receptor-mediated event using novel gonadotropin-releasing hormone analogues.

B. Strulovici, J. Nestor, R. Tahilramani, 1987, Biochemistry.

Effects of enprostil on platelets, endothelial cells, and other cell types, and second messenger systems by which these effects are mediated.

B. Strulovici, A. Allison, W. J. Kowalski, 1986, The American journal of medicine.

Pure β-adrenergic receptor: the single polypeptide confers catecholamine responsiveness to adenylate cyclase

B. Strulovici, M. Caron, R. Lefkowitz, 1983, Nature.

Stimulation by cyclic nucleotides of prostaglandin E production in isolated graafian follicles.

B. Strulovici, U. Zor, H. R. Lindner, 1977, Prostaglandins.

Reconstitution of beta-adrenergic receptors in lipid vesicles: affinity chromatography-purified receptors confer catecholamine responsiveness on a heterologous adenylate cyclase system.

B. Strulovici, C. Strader, M. Caron, 1983, Proceedings of the National Academy of Sciences of the United States of America.

Development of an oxazolopyridine series of dual thrombin/factor Xa inhibitors via structure-guided lead optimization.

Lawrence C Kuo, Berta Strulovici, Daniel R McMasters, 2005, Bioorganic & medicinal chemistry letters.

2-aryl-indolyl maleimides - novel and potent inhibitors of protein kinase C

B. Strulovici, C. Broka, D. Sherman, 1995 .

SCREENING FOR ANTICANCER LEADS FROM MARINE ORGANISMS IN A MECHANISM-BASED DRUG DISCOVERY PROGRAM

B. Strulovici, W. Gerwick, P. Crews, 1994 .

Follicle-stimulating hormone-induced prostaglandin E formation in isolated rat ovarian theca.

B. Strulovici, U. Zor, H. R. Lindner, 1983, The Journal of endocrinology.

Distinct mechanisms of regulation of protein kinase C epsilon by hormones and phorbol diesters.

B. Strulovici, H. Cherwinski, D. Webb, 1991, The Journal of biological chemistry.

Effect of modulators of cytoskeletal function on desensitization and recovery of PGE2-responsive ovarian adenylate cyclase.

B. Strulovici, U. Zor, H. R. Lindner, 1979, Prostaglandins.

Implication of microtubules and microfilaments in the response of the ovarian adenylate cyclase-cyclic AMP system to gonadotropins and prostaglandin E2.

B. Strulovici, U. Zor, H. R. Lindner, 1978, Biochemical and biophysical research communications.

Desensitization and recovery of PGE2-responsive ovarian adenylate cyclase modulated by agents affecting cytoskeletal function.

B. Strulovici, U. Zor, H. R. Lindner, 1979, Advances in experimental medicine and biology.

An Efficient and Fully Automated High-Throughput Transfection Method for Genome-Scale siRNA Screens

Kevin W. Huff, M. Ferrer, B. Strulovici, 2008, Journal of biomolecular screening.

Stimulation of prostaglandin E production by concanavalin A in isolated Graafian follicles.

B. Strulovici, U. Zor, Y. Weinstein, 1981, Prostaglandins.

B. Strulovici, M. Omary, C. Chou, 1992, The Journal of cell biology.

Small Interfering RNA Screens Reveal Enhanced Cisplatin Cytotoxicity in Tumor Cells Having both BRCA Network and TP53 Disruptions

Peter S. Linsley, Marc Ferrer, Stephen H. Friend, 2006, Molecular and Cellular Biology.

Small Interfering RNA Screens Reveal Enhanced Cisplatin Cytotoxicity in Tumor Cells Having both BRCA Network and TP 53 Disruptions ‡

Peter S. Linsley, Marc Ferrer, Stephen H. Friend, 2006 .

Activation of distinct protein kinase C isozymes by phorbol esters: correlation with induction of interleukin 1 beta gene expression.

B. Strulovici, A. Tsou, S. Daniel-Issakani, 1989, Biochemistry.

Interferon alpha induces protein kinase C-epsilon (PKC-epsilon) gene expression and a 4.7-kb PKC-epsilon-related transcript.

B. Strulovici, L. Dekker, S. Constantinescu, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Transmembrane signaling by interferon alpha involves diacylglycerol production and activation of the epsilon isoform of protein kinase C in Daudi cells.

B. Strulovici, N. Reich, L. Pfeffer, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Insulin stimulates the activity of a novel protein kinase C, PKC-epsilon, in cultured fetal chick neurons.

B. Strulovici, K. Heidenreich, L. Brunton, 1990, The Journal of biological chemistry.

Interferon-alpha selectively activates the beta isoform of protein kinase C through phosphatidylcholine hydrolysis.

B. Strulovici, L. Pfeffer, A. Saltiel, 1990, Proceedings of the National Academy of Sciences of the United States of America.

Development of an intact cell reporter gene beta-lactamase assay for G protein-coupled receptors for high-throughput screening.

James Inglese, Peter Hodder, Berta Strulovici, 2003, Analytical biochemistry.

The Use of Strictly Standardized Mean Difference for Hit Selection in Primary RNA Interference High-Throughput Screening Experiments

Marc Ferrer, Joseph F Heyse, Berta Strulovici, 2007, Journal of biomolecular screening.

LRRTM3 promotes processing of amyloid-precursor protein by BACE1 and is a positional candidate gene for late-onset Alzheimer's disease

Shane D. Marine, Amy S. Espeseth, Min Xu, 2006, Proceedings of the National Academy of Sciences.

Activation, desensitization, and recycling of frog erythrocyte beta-adrenergic receptors. Differential perturbation by in situ trypsinization.

B. Strulovici, R. Lefkowitz, 1984, The Journal of biological chemistry.

Immunocharacterization of β‐ and ζ‐subspecies of protein kinase C in bovine neutrophils

B. Strulovici, E. Chambaz, P. Vignais, 1990 .

Automated Application of a Novel High Yield, High Performance Tissue Culture Flask

Eric N. Johnson, Justin Murray, Berta Strulovici, 2008 .

Miniaturization of absorbance assays using the fluorescent properties of white microplates.

Gregory T O'Donnell, M. Ferrer, B. Strulovici, 2005, Analytical biochemistry.

Miniaturization and automation of an ubiquitin ligase cascade enzyme-linked immunosorbent assay in 1,536-well format.

Marc Ferrer, Jason Cassaday, Tarak Shah, 2007, Assay and drug development technologies.

Application of division arrest technology to cell-based HTS: comparison with frozen and fresh cells.

Wei Zheng, Berta Strulovici, Kelli Solly, 2005, Assay and drug development technologies.

Lipopolysaccharide response is linked to the GTP binding protein, Gi2, in the promonocytic cell line U937.

B. Strulovici, A. Spiegel, S. Daniel-Issakani, 1989, The Journal of biological chemistry.

A rational utilization of high-throughput screening affords selective, orally bioavailable 1-benzyl-3-carboxyazetidine sphingosine-1-phosphate-1 receptor agonists.

M. Ferrer, B. Strulovici, S. A. Parent, 2004, Journal of medicinal chemistry.

Elevation of apparent membrane viscosity in ovarian granulosa cells by follicle-stimulating hormone.

B. Strulovici, U. Zor, M. Shinitzky, 1981, Biochimica et biophysica acta.

A β-Lactamase-Dependent Gal4-Estrogen Receptor β Transactivation Assay for the Ultra-High Throughput Screening of Estrogen Receptor β Agonists in a 3,456-Well Format

M. Ferrer, B. Strulovici, L. Mitnaul, 2003 .

A fully automated [35S]GTPgammaS scintillation proximity assay for the high-throughput screening of Gi-linked G protein-coupled receptors.

M. Ferrer, B. Strulovici, James Inglese, 2003, Assay and drug development technologies.

A cell-based β-lactamase reporter gene assay for the identification of inhibitors of hepatitis C virus replication

James Inglese, Marc Ferrer, Berta Strulovici, 2004 .

A Cell-Based Ultra-High-Throughput Screening Assay for Identifying Inhibitors of D-Amino Acid Oxidase

Wei Zheng, Oleg Kornienko, Berta Strulovici, 2006, Journal of biomolecular screening.

Multiplexed Assays by High-Content Imaging for Assessment of GPCR Activity

M. Ferrer, B. Strulovici, V. Reiser, 2008, Journal of biomolecular screening.

INTERNALIZED RECEPTORS RECONSTITUTE CATECHOLAMINE-STIMULATED ADENYLATE CYCLASE ACTIVITY*

B. Strulovici, Robert, Lefkowitz, 2001 .

Hit selection with false discovery rate control in genome-scale RNAi screens

Min Xu, Marc Ferrer, Pei Fen Kuan, 2008, Nucleic acids research.

A 1,536-well ultra-high-throughput siRNA screen to identify regulators of the Wnt/beta-catenin pathway.

Berta Strulovici, Louis Locco, Anthony Kreamer, 2010, Assay and drug development technologies.

Integrating Experimental and Analytic Approaches to Improve Data Quality in Genome-wide RNAi Screens

Xiaohua Douglas Zhang, Marc Ferrer, Joseph F Heyse, 2008, Journal of biomolecular screening.

A cell-based beta-lactamase reporter gene assay for the identification of inhibitors of hepatitis C virus replication.

James Inglese, Marc Ferrer, Berta Strulovici, 2004, Analytical biochemistry.

Identification of Small-Molecule Modulators of Mouse SVZ Progenitor Cell Proliferation and Differentiation Through High-Throughput Screening

Marc Ferrer, Jason Cassaday, Berta Strulovici, 2009, Journal of biomolecular screening.

Activity profile-based siRNA screen to explore the functional genomics of Alzheimer's disease

Shane D. Marine, Amy S. Espeseth, Min Xu, 2007 .

Identification of Small-Molecule Modulators of Mouse SVZ Progenitor Cell Proliferation and Differentiation Through High-Throughput Screening

M. Ferrer, B. Strulovici, Yaping Liu, 2009, Journal of biomolecular screening.

A 1536-well cAMP assay for Gs- and Gi-coupled receptors using enzyme fragmentation complementation.

M. Ferrer, B. Strulovici, Wei Zheng, 2004, Assay and drug development technologies.

Prevention of prostaglandin E2-induced desensitization of rat ovarian cyclic AMP response by concanavalin A.

B. Strulovici, Y. Weinstein, U. Zor,, 1981, Biochemical and biophysical research communications.