S. Tonegawa

发表

Somatic generation of immune diversity

S. Tonegawa, 1988, In Vitro Cellular & Developmental Biology.

Requirement for Hippocampal CA3 NMDA Receptors in Associative Memory Recall

M. Quirk, M. Wilson, S. Tonegawa, 2002, Science.

Optogenetic stimulation of a hippocampal engram activates fear memory recall

K. Deisseroth, S. Tonegawa, Xu Liu, 2012, Nature.

A clustered plasticity model of long-term memory engrams

S. Tonegawa, A. Govindarajan, R. J. Kelleher, 2006, Nature Reviews Neuroscience.

Creating a False Memory in the Hippocampus

S. Tonegawa, Xu Liu, S. Ramirez, 2013, Science.

Successful Execution of Working Memory Linked to Synchronized High-Frequency Gamma Oscillations

S. Tonegawa, Daigo Takeuchi, Junghyup Suh, 2014, Cell.

Somatic generation of antibody diversity.

S. Tonegawa, G. Matthyssens, N. Hozumi, 1976, Nature.

NMDA receptors, place cells and hippocampal spatial memory

M. Wilson, S. Tonegawa, K. Nakazawa, 2004, Nature Reviews Neuroscience.

Dentate Gyrus NMDA Receptors Mediate Rapid Pattern Separation in the Hippocampal Network

M. Wilson, S. Tonegawa, M. Fanselow, 2007, Science.

Impaired Hippocampal Representation of Space in CA1-Specific NMDAR1 Knockout Mice

K. I. Blum, M. Wilson, S. Tonegawa, 1996, Cell.

Preplay of future place cell sequences by hippocampal cellular assemblies

G. Dragoi, S. Tonegawa, 2011, Nature.

The Essential Role of Hippocampal CA1 NMDA Receptor–Dependent Synaptic Plasticity in Spatial Memory

S. Tonegawa, J. Tsien, P. Huerta, 1996, Cell.

Subregion- and Cell Type–Restricted Gene Knockout in Mouse Brain

David J. Anderson, E. Kandel, S. Tonegawa, 1996, Cell.

Impaired synapse elimination during cerebellar development in PKCγ mutant mice

S. Tonegawa, Masahiko Watanabe, M. Kano, 1995, Cell.

Deficient hippocampal long-term potentiation in alpha-calcium-calmodulin kinase II mutant mice.

Alcino J. Silva, S. Tonegawa, C. Stevens, 1992, Science.

Reduced hippocampal long-term potentiation and context-specific deficit in associative learning in mGluR1 mutant mice

S. Tonegawa, Christian Rosenmund, K. Herrup, 1994, Cell.

PKCγ mutant mice exhibit mild deficits in spatial and contextual learning

S. Tonegawa, J. Kim, A. Abeliovich, 1993, Cell.

Impaired motor coordination correlates with persistent multiple climbing fiber innervation in PKCγ mutant mice

Richard F. Thompson, S. Tonegawa, S. Bao, 1995, Cell.

Deficient cerebellar long-term depression and impaired motor learning in mGluR1 mutant mice

S. Tonegawa, T. Zwingman, M. Stanton, 1994, Cell.

Impaired spatial learning in alpha-calcium-calmodulin kinase II mutant mice.

Alcino J. Silva, S. Tonegawa, A. J. Silva, 1992, Science.

Modified hippocampal long-term potentiation in PKCγ-mutant mice

Alcino J. Silva, S. Tonegawa, Y. Goda, 1993, Cell.

Entorhinal Cortex Layer III Input to the Hippocampus Is Crucial for Temporal Association Memory

Alexander J. Rivest, S. Tonegawa, Junghyup Suh, 2011, Science.

Island Cells Control Temporal Association Memory

S. Tonegawa, Junghyup Suh, M. Pignatelli, 2014, Science.

Entorhinal Cortical Ocean Cells Encode Specific Contexts and Drive Context-Specific Fear Memory

Lacey J. Kitch, S. Tonegawa, M. Schnitzer, 2015, Neuron.

Memory Engram Cells Have Come of Age

S. Tonegawa, Xu Liu, S. Ramirez, 2015, Neuron.

Memory engram storage and retrieval

Dheeraj S. Roy, S. Tonegawa, M. Pignatelli, 2015, Current Opinion in Neurobiology.

Genetic analysis of the calcineurin pathway identifies members of the EGR gene family, specifically EGR3, as potential susceptibility candidates in schizophrenia

Susumu Tonegawa, Yoshio Minabe, Kazuo Yamada, 2007, Proceedings of the National Academy of Sciences.

Translational Control by MAPK Signaling in Long-Term Synaptic Plasticity and Memory

Hyejin Kang, Susumu Tonegawa, Hae-Yoon Jung, 2004, Cell.

Bidirectional switch of the valence associated with a hippocampal contextual memory engram

S. Tonegawa, Xu Liu, S. Ramirez, 2014, Nature.

Ventral CA1 neurons store social memory

Dheeraj S. Roy, S. Tonegawa, S. Itohara, 2016, Science.

Somatic generation of antibody diversity

S. Tonegawa, 1983, Nature.

NMDA Receptor-Dependent Ocular Dominance Plasticity in Adult Visual Cortex

M. Bear, S. Tonegawa, K. Nakazawa, 2003, Neuron.

Young Dentate Granule Cells Mediate Pattern Separation, whereas Old Granule Cells Facilitate Pattern Completion

S. Tonegawa, D. Buhl, M. Fanselow, 2012, Cell.

Cell type–specific genetic and optogenetic tools reveal hippocampal CA2 circuits

Ian R. Wickersham, Alexander J. Rivest, S. Tonegawa, 2013 .

Entorhinal–hippocampal neuronal circuits bridge temporally discontiguous events

S. Tonegawa, C. MacDonald, T. Kitamura, 2015, Learning & memory.

Basolateral to Central Amygdala Neural Circuits for Appetitive Behaviors

S. Tonegawa, S. Muralidhar, Joshua Kim, 2017, Neuron.

Activating positive memory engrams suppresses depression-like behaviour

S. Tonegawa, Xu Liu, S. Ramirez, 2015, Nature.

Brain-wide mapping of contextual fear memory engram ensembles supports the dispersed engram complex hypothesis

Dheeraj S. Roy, Sachie K. Ogawa, S. Tonegawa, 2019, bioRxiv.

Formation of Temporal Memory Requires NMDA Receptors within CA1 Pyramidal Neurons

M. Wilson, S. Tonegawa, Linus D. Sun, 2000, Neuron.

CA1-specific N-methyl-d-aspartate receptor knockout mice are deficient in solving a nonspatial transverse patterning task

S. Tonegawa, H. Eichenbaum, L. Rondi-Reig, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Retention of NMDA receptor NR2 subunits in the lumen of endoplasmic reticulum in targeted NR1 knockout mice

S. Tonegawa, Masahiko Watanabe, Akira Kato, 2003, Proceedings of the National Academy of Sciences of the United States of America.

In Search of Engram Cells

Dheeraj S. Roy, S. Tonegawa, 2017 .

Hippocampal CA3 NMDA Receptors Are Crucial for Memory Acquisition of One-Time Experience

M. Quirk, M. Wilson, S. Tonegawa, 2003, Neuron.

Cell type-specific genetic and optogenetic tools reveal novel hippocampal CA2 circuits

Ian R. Wickersham, Alexander J. Rivest, S. Tonegawa, 2013, Nature Neuroscience.

Reduced stress defense in heme oxygenase 1-deficient cells.

S. Tonegawa, K. Poss, Susumu Tonegawa, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Memory retrieval by activating engram cells in mouse models of early Alzheimer’s disease

Dheeraj S. Roy, S. Tonegawa, M. Pignatelli, 2016, Nature.

Locus coeruleus input to hippocampal CA3 drives single-trial learning of a novel context

S. Tonegawa, K. Abe, Chen Sun, 2017, Proceedings of the National Academy of Sciences.

A tissue-specific transcription enhancer element is located in the major intron of a rearranged immunoglobulin heavy chain gene

S. Tonegawa, S. Morrison, S. Gillies, 1983, Cell.

BDNF Regulates the Maturation of Inhibition and the Critical Period of Plasticity in Mouse Visual Cortex

L. Maffei, M. Bear, S. Tonegawa, 1999, Cell.

Distinct speed dependence of entorhinal island and ocean cells, including respective grid cells

Lacey J. Kitch, S. Tonegawa, M. Schnitzer, 2015, Proceedings of the National Academy of Sciences.

Antagonistic negative and positive neurons of the basolateral amygdala

Michele Pignatelli, Susumu Tonegawa, Shigeyoshi Itohara, 2016, Nature Neuroscience.

Molecular genetic analysis of synaptic plasticity, activity-dependent neural development, learning, and memory in the mammalian brain.

C Chen, S. Tonegawa, C. Chen, 1997, Annual review of neuroscience.

Impaired Sequential Egocentric and Allocentric Memories in Forebrain-Specific–NMDA Receptor Knock-Out Mice during a New Task Dissociating Strategies of Navigation

Alain Berthoz, Susumu Tonegawa, Laure Rondi-Reig, 2006, The Journal of Neuroscience.

Direct Medial Entorhinal Cortex Input to Hippocampal CA1 Is Crucial for Extended Quiet Awake Replay

Susumu Tonegawa, Jun Yamamoto, S. Tonegawa, 2017, Neuron.

RAG-1-deficient mice have no mature B and T lymphocytes

Susumu Tonegawa, Karl Herrup, Peter Mombaerts, 1992, Cell.

MHC class I expression and CD8+ T cell development in TAP1/beta 2-microglobulin double mutant mice.

S. Tonegawa, M. Sabatine, H. Ploegh, 1995, International immunology.

Inception of a false memory by optogenetic manipulation of a hippocampal memory engram

Susumu Tonegawa, Steve Ramirez, S. Tonegawa, 2014, Philosophical Transactions of the Royal Society B: Biological Sciences.

Hippocampal CA3 NMDA Receptors Are Crucial for Adaptive Timing of Trace Eyeblink Conditioned Response

S. Tonegawa, K. Nakazawa, M. Kano, 2006, The Journal of Neuroscience.

Abnormal fear response and aggressive behavior in mutant mice deficient for alpha-calcium-calmodulin kinase II.

S. Tonegawa, R. Greene, D. Rainnie, 1994, Science.

Dopamine D2 Long Receptor-Deficient Mice Display Alterations in Striatum-Dependent Functions

Susumu Tonegawa, S. Tonegawa, M. Kung, 2000, The Journal of Neuroscience.

Translational Regulatory Mechanisms in Persistent Forms of Synaptic Plasticity

Susumu Tonegawa, S. Tonegawa, A. Govindarajan, 2004, Neuron.

Enhancement of Learning and Memory by Elevating Brain Magnesium

Susumu Tonegawa, Min Zhuo, Guosong Liu, 2010, Neuron.

Transgenic Inhibition of Synaptic Transmission Reveals Role of CA3 Output in Hippocampal Learning

Susumu Tonegawa, Thomas J. McHugh, Derek L. Buhl, 2008, Science.

The Dendritic Branch Is the Preferred Integrative Unit for Protein Synthesis-Dependent LTP

Susumu Tonegawa, Inbal Israely, S. Tonegawa, 2011, Neuron.

Altered Cortical Synaptic Morphology and Impaired Memory Consolidation in Forebrain- Specific Dominant-Negative PAK Transgenic Mice

Susumu Tonegawa, Hae-Yoon Jung, Sumantra Chattarji, 2004, Neuron.

Amygdala Reward Neurons Form and Store Fear Extinction Memory

S. Tonegawa, Joshua Kim, X. Zhang, 2020, Neuron.

Restricted association of V and J-C gene segments for mouse lambda chains.

S. Tonegawa, T. Imanishi‐Kari, H. Eisen, 1984, Proceedings of the National Academy of Sciences of the United States of America.

Intestinal intraepithelial lymphocytes are a distinct set of γδ T cells

S. Tonegawa, C. Janeway, W. Haser, 1988, Nature.

Intestinal intraepithelial lymphocytes are a distinct set of gamma delta T cells.

S. Tonegawa, C. Janeway, W. Haser, 1988, Nature.

Homeostatic regulation of intestinal epithelia by intraepithelial gamma delta T cells.

S. Tonegawa, S. Itohara, P. Mombaerts, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Activation of a translocated human c-myc gene by an enhancer in the immunoglobulin heavy-chain locus

W. S. Hayward, S. Tonegawa, A. Hayday, 1984, Nature.

CD28 costimulation is crucial for the development of spontaneous autoimmune encephalomyelitis.

S. Tonegawa, T. Mak, J. Penninger, 1999, Journal of immunology.

Electrophoretically homogeneous myeloma light chain mRNA and its translation in vitro.

S. Tonegawa, I. Baldi, Susumu Tonegawa, 1973, Biochemical and biophysical research communications.

39th Annual European Brain and Behaviour Society Abstracts

Maria V. Sanchez-Vives, R. C. Honey, J. L. Moore, 2007, Neural Plasticity.

The molecules of the immune system.

S. Tonegawa, S Tonegawa, 1985, Scientific American.

Direct excitation of parvalbumin‐positive interneurons by M1 muscarinic acetylcholine receptors: roles in cellular excitability, inhibitory transmission and cognition

Kurt E. Stoll, John M. Ball, K. Deisseroth, 2014, The Journal of physiology.

Immunobiology of Murine T Cruzi Infection: The Predominance of Parasite‐nonspecific Responses and the Activation of TCRIT Cells

S. Tonegawa, S. Itohara, A. Coutinho, 1989, Immunological reviews.

Somatic reorganization of immunoglobulin genes during lymphocyte differentiation.

S. Tonegawa, Y. Kurosawa, H. Sakano, 1981, Cold Spring Harbor symposia on quantitative biology.

Identification of Novel Biomarker For Human Uterine Leiomyosarcoma

H. Aburatani, S. Tonegawa, Y. Kanai, 2014 .

Proteasome LMP2/β1i subunit as biomarker for human uterine leiomyosarcoma

H. Aburatani, S. Tonegawa, Y. Kanai, 2014 .

The Proteasome Subunit LMP2/b1i In the Female Genital System

H. Aburatani, S. Tonegawa, Y. Kanai, 2013 .

A differential-avidity model for T-cell selection.

S. Tonegawa, P. Ashton‐Rickardt, Susumu Tonegawa, 1994, Immunology today.

Creation of a large genomic deletion at the T-cell antigen receptor beta-subunit locus in mouse embryonic stem cells by gene targeting.

S. Tonegawa, P. Mombaerts, A. Clarke, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Differential attentional control mechanisms by two distinct noradrenergic coeruleo-frontal cortical pathways

S. Tonegawa, Daigo Takeuchi, M. Pignatelli, 2020, Proceedings of the National Academy of Sciences.

Profiling of Target Molecules for Immunotherapy in Mesenchymal Tumors

H. Aburatani, S. Tonegawa, Y. Kanai, 2019, Journal of clinical medicine research.

Molecular Pathology and Novel Clinical Therapy for Uterine Leiomyosarcoma.

H. Aburatani, S. Tonegawa, Y. Kanai, 2016, Anticancer research.

Highly restricted expression of the thymus leukemia antigens on intestinal epithelial cells

S. Tonegawa, S. Itohara, L. Van Kaer, 1991, The Journal of experimental medicine.

Transgenic mice demonstrate that epithelial homing of gamma/delta T cells is determined by cell lineages independent of T cell receptor specificity

S. Tonegawa, S. Itohara, M. Katsuki, 1990, The Journal of experimental medicine.

Linkage of the four v subclass heavy chain genes

S. Tonegawa, A. Traunecker, W. Roeder, 2003 .

Diagnostic Biomarker Candidates Including NT5DC2 for Human Uterine Mesenchymal Tumors

S. Tonegawa, N. Yaegashi, I. Konishi, 2021 .

Potential biomarkers associated with malignancy in uterine mesenchymal tumors

S. Tonegawa, N. Yaegashi, I. Konishi, 2021, European Journal of Gynaecological Oncology.

Contribution of α/β and γ/δ T lymphocytes to immunity against Mycobacterium bovis Bacillus Calmette Guérin: studies with T cell receptor‐deficient mutant mice

S. Tonegawa, S. Kaufmann, P. Mombaerts, 1995 .

Organization of four mouse lambda light chain immunoglobulin genes.

S. Tonegawa, B. Blomberg, H. Eisen, 1981, Proceedings of the National Academy of Sciences of the United States of America.

Tolerance Induction and Autoimmune Encephalomyelitis Amelioration After Administration of Myelin Basic Protein–derived Peptide

S. Tonegawa, S. Marusic, S. Marušić, 1997, The Journal of experimental medicine.

Structure, organization, and somatic rearrangement of T cell gamma genes

S. Tonegawa, A. Hayday, D. Kranz, 1985, Cell.

Expression of the T-cell-specific γ gene is unnecessary in T cells recognizing class II MHC determinants

S. Tonegawa, L. Glimcher, A. Maxam, 1985, Nature.

Functional expression of a microinjected Edα gene in C57BL/6 transgenic mice

S. Tonegawa, S. Akira, K. Yamamura, 1985, Nature.

Early expression of a T-cell receptor beta-chain transgene suppresses rearrangement of the V gamma 4 gene segment.

S. Tonegawa, S. Ryser, M. Bonneville, 1988, Proceedings of the National Academy of Sciences of the United States of America.

The T cell receptor repertoire of intestinal intraepithelial gammadelta T lymphocytes is influenced by genes linked to the major histocompatibility complex and to the T cell receptor loci.

S. Tonegawa, P. Pereira, D. Gerber, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Ontogenic Development and Tissue Distribution of V-yl-expressing y/b T Lymphocytes in Normal Mice

S. Tonegawa, P. Pereira, D. Gerber, 2003 .

gamma/delta T cell-deficient mice have impaired mucosal immunoglobulin A responses

S. Tonegawa, J. Mcghee, H. Kiyono, 1996, The Journal of experimental medicine.

Ontogenic development and tissue distribution of V gamma 1-expressing gamma/delta T lymphocytes in normal mice

S. Tonegawa, P. Pereira, D. Gerber, 1995, The Journal of experimental medicine.

Limited diversity of the rearranged T-cell gamma gene.

S. Tonegawa, D. Kranz, M. Heller, 1985, Nature.

A functional gamma gene formed from known gamma-gene segments is not necessary for antigen-specific responses of murine cytotoxic T lymphocytes.

S. Tonegawa, D. Kranz, H. Eisen, 1986, Nature.

Cell type-specific enhancer element associated with a mouse MHC gene, Eβ

S. Tonegawa, S. Gillies, V. Folsom, 1984, Nature.

Expression of cloned immunoglobulin genes introduced into mouse L cells.

S. Tonegawa, S. Gilles, 1983, Nucleic acids research.

Functional analysis of the TCR alpha- beta+ cells that accumulate in the pneumonic lung of influenza virus-infected TCR-alpha-/- mice.

S. Tonegawa, M. Eichelberger, P. Doherty, 1995, Journal of immunology.

Transgenic Mice Demonstrate That Epithelial Homing of Y/b T Cells Is Determined by Cell Lineages Independent of T Cell Receptor Specificity

S. Tonegawa, S. Itohara, M. Katsuki, 2022 .

Diversity, development, ligands, and probable functions of gamma delta T cells.

S. Tonegawa, S. Itohara, M. Katsuki, 1989, Cold Spring Harbor symposia on quantitative biology.

Blockage of αβ T-cell development by TCR γδ transgenes

S. Tonegawa, M. Katsuki, M. Bonneville, 1989, Nature.

T cell receptor-gamma and -delta genes preferentially utilized by adult thymocytes for the surface expression.

S. Tonegawa, I. Ishida, O. Kanagawa, 1989, Journal of immunology.

Diversity, Development, Ligands, and Probable Functions of γδ T Cells

S. Tonegawa, S. Itohara, C. Janeway, 1989 .

gammadelta T cells regulate mucosally induced tolerance in a dose-dependent fashion.

S. Tonegawa, J. Mcghee, H. Kiyono, 1999, International immunology.

Development and selection of γδ T cells

S. Tonegawa, W. Haas, 1992 .

Homing of a gamma delta thymocyte subset with homogeneous T-cell receptors to mucosal epithelia.

S. Tonegawa, S. Itohara, M. Bonneville, 1990, Nature.

Restoration of early thymocyte differentiation in T-cell receptor beta-chain-deficient mutant mice by transmembrane signaling through CD3 epsilon.

S. Tonegawa, C. Levelt, P. Mombaerts, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Genetic Origins of B and T Cell Antibodies

S. Tonegawa, Y. Kurosawa, H. Boehmer, 1983 .

ORGANIZATION AND EXPRESSION OF MOUSE λ LIGHT CHAIN IMMUNOGLOBULIN GENES

S. Tonegawa, B. Blomberg, 1982 .

Inhibition of intrathymic T cell development by expression of a transgenic antagonist peptide.

S. Tonegawa, C. Levelt, E. Mizoguchi, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Cytokine imbalance and autoantibody production in T cell receptor-alpha mutant mice with inflammatory bowel disease

S. Tonegawa, E. Mizoguchi, A. Bhan, 1996, The Journal of experimental medicine.

Complete primary structures of the E beta chain and gene of the mouse major histocompatibility complex.

S. Tonegawa, R. Maki, H. Saito, 1983, Proceedings of the National Academy of Sciences of the United States of America.

Regulation of T-cell receptor gene expression in human T-cell development.

S. Tonegawa, M. Collins, M. Ritter, 1985, Proceedings of the National Academy of Sciences of the United States of America.

Functional and inducible expression of a transfected murine class II major histocompatibility complex gene.

S. Tonegawa, P. Marrack, J. Kappler, 1984, Proceedings of the National Academy of Sciences of the United States of America.

Extrathymic origin of intestinal intraepithelial lymphocytes bearing T-cell antigen receptor gamma delta.

S. Tonegawa, S. Itohara, A. Coutinho, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Selection of gamma delta T cells with canonical T-cell antigen receptors in fetal thymus.

S. Tonegawa, S. Itohara, 1990, Proceedings of the National Academy of Sciences of the United States of America.

Altered cortical spine morphology and impaired memory consolidation in forebrain-specific dominant negative p21-activated Kinase (PAK) transgenic mice

S. Tonegawa, A. Kirkwood, S. Chattarji, 2004 .

Differential reactivity of residual CD8+ T lymphocytes in TAP1 and β2‐microglobulin mutant mice

S. Tonegawa, H. Ploegh, H. Ljunggren, 1995 .

YOSHIKAZU KUROSAWA AND SUSUMU TONEGAWA

S. Tonegawa, Y. Kurosawa, 2003 .

Blockage of alpha beta T-cell development by TCR gamma delta transgenes.

S. Tonegawa, M. Katsuki, M. Bonneville, 1989, Nature.

Activation of a translocated c-myc gene: role of structural alterations in the upstream region.

W. S. Hayward, S. Tonegawa, A. Hayday, 1984, Proceedings of the National Academy of Sciences of the United States of America.

Somatic Recombination and Structure of an Immunoglobulin Gene

S. Tonegawa, C. Brack, M. Hirama, 1979 .

V and C parts of immunoglobulin κ-chain genes are separate in myeloma

S. Tonegawa, G. Matthyssens, 1978, Nature.

Heme oxygenase 1 is required for mammalian iron reutilization.

S. Tonegawa, K. Poss, 1997, Proceedings of the National Academy of Sciences of the United States of America.

High- and low-affinity single-peptide/MHC ligands have distinct effects on the development of mucosal CD8alphaalpha and CD8alphabeta T lymphocytes.

S. Tonegawa, S. Simpson, C. Levelt, 1999, Proceedings of the National Academy of Sciences of the United States of America.

EncephalomyelitisDevelopment of Spontaneous Autoimmune CD28 Costimulation Is Crucial for the

S. Tonegawa, T. Mak, J. Penninger, 1999 .

Dynamics of Immunoglobulin Genes

S. Tonegawa, G. Matthyssens, N. Hozumi, 1977, Immunological reviews.

T cell receptor delta gene mutant mice: independent generation of alpha beta T cells and programmed rearrangements of gamma delta TCR genes.

S. Tonegawa, S. Itohara, P. Mombaerts, 1993, Cell.

TAP1‐independent loading of class I molecules by exogenous viral proteins

S. Tonegawa, H. Pircher, R. Zinkernagel, 1995, European journal of immunology.

Regulation of thymocyte development through CD3: Functional dissociation between p56lck and CD3ζ in early thymic selection

S. Tonegawa, P. Mombaerts, H. Kohler, 1995 .

Close linkage of the mouse and human CD3 gamma- and delta-chain genes suggests that their transcription is controlled by common regulatory elements.

S. Tonegawa, H. Clevers, W. Haser, 1987, Proceedings of the National Academy of Sciences of the United States of America.

Antibody and T-cell receptors.

S. Tonegawa, 1988, JAMA.

The human T-cell receptor α-chain gene maps to chromosome 14

S. Tonegawa, P. Goodfellow, M. Collins, 1985 .

NMDA Receptor-Dependent Refinement of Somatotopic Maps

S. Tonegawa, P. Huerta, T. Iwasato, 1997, Neuron.

A potential diagnostic biomarker: Proteasome LMP2/b1i-differential expression in human uterus neoplasm

H. Aburatani, S. Tonegawa, N. Yaegashi, 2012 .

Different gamma delta T-cell receptors are expressed on thymocytes at different stages of development.

S. Tonegawa, M. Bonneville, E. Krecko, 1989, Proceedings of the National Academy of Sciences of the United States of America.

Role of protein kinase C family in the cerebellum‐dependent adaptive learning of horizontal optokinetic response eye movements in mice

S. Tonegawa, S. Itohara, A. Katoh, 2003, The European journal of neuroscience.

T-cell receptor gamma delta and gamma transgenic mice suggest a role of a gamma gene silencer in the generation of alpha beta T cells.

S. Tonegawa, S. Itohara, M. Bonneville, 1990, Proceedings of the National Academy of Sciences of the United States of America.

Cloning and sequencing of murine T3 gamma cDNA from a subtractive cDNA library

S. Tonegawa, W. Haser, H. Saito, 1987, The Journal of experimental medicine.

Altered natural killer cell repertoire in Tap-1 mutant mice.

S. Tonegawa, H. Ploegh, H. Ljunggren, 1994, Proceedings of the National Academy of Sciences of the United States of America.

A third rearranged and expressed gene in a clone of cytotoxic T lymphocytes

S. Tonegawa, A. Hayday, D. Kranz, 1984, Nature.

A phosphorylated, disulfide-linked membrane protein in murine cytotoxic T lymphocytes.

S. Tonegawa, J. Lieberman, D. Kranz, 1986, Proceedings of the National Academy of Sciences of the United States of America.

Transcription of mouse kappa chain genes: implications for allelic exclusion.

S. Tonegawa, J. Seidman, P. Leder, 1980, Proceedings of the National Academy of Sciences of the United States of America.

The beta 1 domain of the mouse E beta chain is important for restricted antigen presentation to helper T-cell hybridomas.

S. Tonegawa, D. Gay, V. Folsom, 1985, Proceedings of the National Academy of Sciences of the United States of America.

Do all murine intraepithelial leukocytes (IEL) have T cell receptor rearrangements

S. Tonegawa, R. Stead, J. Bienenstock, 1990 .

Attachment of an anti-receptor antibody to non-target cells renders them susceptible to lysis by a clone of cytotoxic T lymphocytes.

S. Tonegawa, D. Kranz, H. Eisen, 1984, Proceedings of the National Academy of Sciences of the United States of America.

Phorbol ester effects at hippocampal synapses act independently of the gamma isoform of PKC.

S. Tonegawa, Y. Goda, C. Stevens, 1996, Learning & memory.

Expression of αv and β3 integrin chains on murine lymphocytes

S. Tonegawa, P. Pereira, D. Gerber, 1996 .

Intermediates in the assembly of φX174

S. Tonegawa, M. Hayashi, 1970 .

Functional Analysis of the TCRa ” + Cells That Accumulate in the Pneumonic Lung of Influenza Virus-Infected TCR-U-” Mice ’

S. Tonegawa, M. Eichelberger, P. Doherty, 2001 .

Different roles of alpha beta and gamma delta T cells in immunity against an intracellular bacterial pathogen.

S. Tonegawa, S. Kaufmann, P. Mombaerts, 1993, Nature.

Myelin Basic Protein–specific T Helper 2 (Th2) Cells Cause Experimental Autoimmune Encephalomyelitis in Immunodeficient Hosts Rather than Protect Them from the Disease

S. Tonegawa, C. Raine, J. Lafaille, 1997, The Journal of experimental medicine.

Complete primary structure of a heterodimeric T-cell receptor deduced from cDNA sequences

S. Tonegawa, A. Hayday, D. Kranz, 1984, Nature.

Recognition of a self major histocompatibility complex TL region product by y6 T-cell receptors

S. Tonegawa, S. Itohara, C. Janeway, 2022 .

High incidence of spontaneous autoimmune encephalomyelitis in immunodeficient anti-myelin basic protein T cell receptor transgenic mice

Susumu Tonegawa, S. Tonegawa, M. Katsuki, 1994, Cell.

Dopamine D1 receptor mutant mice are deficient in striatal expression of dynorphin and in dopamine-mediated behavioral responses

Ming Xu, Susumu Tonegawa, Ann M. Graybiel, 1994, Cell.

Preserved acute pain and reduced neuropathic pain in mice lacking PKCgamma.

S. Tonegawa, A. Basbaum, A. Malmberg, 1997, Science.

Cortex-restricted disruption of NMDAR1 impairs neuronal patterns in the barrel cortex

Susumu Tonegawa, Shigeyoshi Itohara, Thomas Knöpfel, 2000, Nature.

Susumu Tonegawa, Chong Chen, Reha S. Erzurumlu, 1994, Cell.

Modification of NMDA Receptor Channels and Synaptic Transmission by Targeted Disruption of the NR2C Gene

S. Tonegawa, D. Rossi, N. Slater, 1996, The Journal of Neuroscience.

CA1 long-term potentiation is diminished but present in hippocampal slices from alpha-CaMKII mutant mice.

S. Tonegawa, R. Malinow, H. Hinds, 1998, Learning & memory.

- CaMKII Mutant Mice α Hippocampal Slices from CA 1 Long-Term Potentiation Is Diminished but Present in

S. Tonegawa, R. Malinow, H. Hinds, 1998 .

The role of calcium–calmodulin kinase II in three forms of synaptic plasticity

Susumu Tonegawa, C. Stevens, S. Tonegawa, 1994, Current Biology.

Essential function of α-calcium/calmodulin-dependent protein kinase II in neurotransmitter release at a glutamatergic central synapse

S. Tonegawa, K. Nakazawa, V. Bolshakov, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Persistent Multiple Climbing Fiber Innervationof Cerebellar Purkinje Cellsin Mice Lacking mGluR1

Susumu Tonegawa, Masahiko Watanabe, Masanobu Kano, 1997, Neuron.

Targeted gene deletion of heme oxygenase 2 reveals neural role for carbon monoxide.

S. Tonegawa, S. Snyder, S. Jaffrey, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Hippocampal long-term potentiation is normal in heme oxygenase-2 mutant mice

Mark J. Thomas, S. Tonegawa, K. Poss, 1995, Neuron.

Skeletal and CNS Defects in Presenilin-1-Deficient Mice

S. Tonegawa, D. Selkoe, R. Bronson, 1997, Cell.

Forebrain-Specific Calcineurin Knockout Selectively Impairs Bidirectional Synaptic Plasticity and Working/Episodic-like Memory

Hongkui Zeng, Mark F. Bear, Susumu Tonegawa, 2001, Cell.

Control of CA3 Output by Feedforward Inhibition Despite Developmental Changes in the Excitation–Inhibition Balance

S. Tonegawa, C. Torborg, C. McBain, 2010, The Journal of Neuroscience.

Cellular / Molecular Control of CA 3 Output by Feedforward Inhibition Despite Developmental Changes in the Excitation – Inhibition Balance

S. Tonegawa, C. Torborg, C. McBain, 2010 .

Engram Cell Excitability State Determines the Efficacy of Memory Retrieval

Michele Pignatelli, Susumu Tonegawa, Tomás J. Ryan, 2019, Neuron.

Alpha calcium/calmodulin kinase II mutant mice: deficient long-term potentiation and impaired spatial learning.

C F Stevens, S. Tonegawa, C. Stevens, 1992, Cold Spring Harbor symposia on quantitative biology.

Spinocerebellar mossy fiber terminal topography in the NR2C/PKCγ double mutant cerebellum

S. Tonegawa, Z. Ji, M. Vogel, 1996 .

Short communication Spinocerebellar mossy fiber terminal topography in the NR2C/PKC3/ double mutant cerebellum

S. Tonegawa, Z. Ji, M. Vogel, 1996 .

The gene knockout technology for the analysis of learning and memory, and neural development.

Alcino J. Silva, S. Tonegawa, Y. Goda, 1995, Progress in brain research.

Bcl-2 promotes regeneration of severed axons in mammalian CNS

G. Schneider, S. Tonegawa, D. Chen, 1997, Nature.

Memory engrams: Recalling the past and imagining the future

Susumu Tonegawa, Sheena A. Josselyn, S. Tonegawa, 2020, Science.

Science Journals — AAAS

S. Tonegawa, S. Josselyn, 2018 .

Gamma/delta cells.

S. Tonegawa, P. Pereira, W. Haas, 1993, Annual review of immunology.

Homing of a γδ thymocyte subset with homogeneous T-cell receptors to mucosal epithelia

S. Tonegawa, S. Itohara, M. Bonneville, 1990, Nature.

Localization of gamma/delta T cells to the intestinal epithelium is independent of normal microbial colonization

S. Tonegawa, S. Itohara, A. Coutinho, 1990, The Journal of experimental medicine.

Different roles of αβ and γδ T cells in immunity against an intracellular bacterial pathogen

S. Tonegawa, S. Kaufmann, P. Mombaerts, 1993, Nature.

Evidence for somatic rearrangement of immunoglobulin genes coding for variable and constant regions.

S. Tonegawa, N. Hozumi, N Hozumi, 1976, Proceedings of the National Academy of Sciences of the United States of America.

Structure of a cytotoxic T-lymphocyte-specific gene shows a strong homology to fibrinogen beta and gamma chains.

S. Tonegawa, W. Haser, H. Saito, 1987, Proceedings of the National Academy of Sciences of the United States of America.

Exon shuffling generates an immunoglobulin heavy chain gene.

S. Tonegawa, H. Sakano, A. Traunecker, 1980, Proceedings of the National Academy of Sciences of the United States of America.

Engrams and circuits crucial for systems consolidation of a memory

Takashi Kitamura, Sachie K Ogawa, Dheeraj S Roy, 2017, Science.

Spontaneous development of inflammatory bowel disease in T cell receptor mutant mice

S. Tonegawa, L. Glimcher, P. Mombaerts, 1993, Cell.

Elimination of cocaine-induced hyperactivity and dopamine-mediated neurophysiological effects in dopamine D1 receptor mutant mice

S. Tonegawa, A. Graybiel, F. J. White, 1994, Cell.

B lineage--specific interactions of an immunoglobulin enhancer with cellular factors in vivo.

G. Church, S. Tonegawa, W. Gilbert, 1985, Science.

The Identification of Somatic Mutations in Interferon-g Signal Molecules in Human Uterine Leiomyosarcoma

H. Aburatani, S. Tonegawa, Y. Kanai, 2016 .

The somatic mutations in Interferon-γ signal molecules in human uterine leiomyosarcoma

H. Aburatani, S. Tonegawa, Y. Kanai, 2015 .

The Alzheimer-related gene presenilin 1 facilitates notch 1 in primary mammalian neurons.

B T Hyman, S. Tonegawa, B. Hyman, 1999, Brain research. Molecular brain research.

Evidence for a differential avidity model of T cell selection in the thymus

S. Tonegawa, H. Pircher, R. Zinkernagel, 1994, Cell.

Impaired Spatial Learning in L-Calcium-Calmodulin Kinase Mutant Mice

S. B. Kater, Alcino J. Silva, S. Tonegawa, 2022 .

Mutations in T-cell antigen receptor genes α and β block thymocyte development at different stages

S. Tonegawa, M. Rudnicki, R. Jaenisch, 1992, Nature.

Sequences of mouse immunoglobulin light chain genes before and after somatic changes

S. Tonegawa, O. Bernard, N. Hozumi, 1978, Cell.

Neural tube defects and abnormal brain development in F52-deficient mice.

S. Tonegawa, T. Sasaoka, M. Wu, 1996, Proceedings of the National Academy of Sciences of the United States of America.

CD3δ deficiency arrests development of the αβ but not the γδ T cell lineage

S. Tonegawa, B. Alarcón, A. De La Hera, 1997 .

Domains of the TCR beta-chain required for early thymocyte development

S. Tonegawa, A. Berns, J. Iacomini, 1996, The Journal of experimental medicine.

Characterization of immature thymocyte lines derived from T-cell receptor or recombination activating gene 1 and p53 double mutant mice.

S. Tonegawa, T. Jacks, P. Mombaerts, 1995, Proceedings of the National Academy of Sciences of the United States of America.

An activated lck transgene promotes thymocyte development in RAG-1 mutant mice.

S. Tonegawa, R. Perlmutter, T. Mak, 1994, Immunity.

Onset of TCR-beta gene rearrangement and role of TCR-beta expression during CD3-CD4-CD8- thymocyte differentiation.

S. Tonegawa, P. Mombaerts, A. Zlotnik, 1994, Journal of immunology.

Developmental regulation of T-cell receptor gene expression

S. Tonegawa, R. Garman, D. Raulet, 1985, Nature.

Sequences at the somatic recombination sites of immunoglobulin light-chain genes

Hitoshi Sakano, Susumu Tonegawa, S. Tonegawa, 1979, Nature.

Diversity, development, ligands, and probable functions of gamma delta T cells.

S. Tonegawa, S. Itohara, C. Janeway, 1991, Advances in experimental medicine and biology.

Unusual organization and diversity of T-cell receptor a-chain genes

S. Tonegawa, A. Hayday, J. Heilig, 1985, Nature.

Cell-type-specific contacts to immunoglobulin enhancers in nuclei

G. Church, S. Tonegawa, W. Gilbert, 1985, Nature.

Steve Ramirez Creating a False Memory in the Hippocampus

S. Tonegawa, Xu Liu, S. Ramirez, 2013 .

Mutant Mice and Neuroscience: Recommendations Concerning Genetic Background

Hee-Sup Shin, Susumu Tonegawa, Michael P. Stryker, 1997, Neuron.

Two types of somatic recombination are necessary for the generation of complete immunoglobulin heavy-chain genes

Hitoshi Sakano, Susumu Tonegawa, S. Tonegawa, 1980, Nature.

Domains and the hinge region of an immunoglobulin heavy chain are encoded in separate DNA segments

S. Tonegawa, H. Sakano, R. Wall, 1979, Nature.

Sequence of a mouse germ-line gene for a variable region of an immunoglobulin light chain.

S. Tonegawa, W. Gilbert, A. Maxam, 1978, Proceedings of the National Academy of Sciences of the United States of America.

Surface expression of alternative forms of the TCR/CD3 complex.

S. Tonegawa, D. Kappes, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Rescue of fragile X syndrome phenotypes in Fmr1 KO mice by the small-molecule PAK inhibitor FRAX486

S. Tonegawa, A. Govindarajan, Se-Young Choi, 2013, Proceedings of the National Academy of Sciences.

Inhibition of p21-activated kinase rescues symptoms of fragile X syndrome in mice

S. Tonegawa, S. Chattarji, Han-Seam Choi, 2007, Proceedings of the National Academy of Sciences.

Somatic mutation creates diversity in the major group of mouse immunoglobulin kappa light chains

S. Tonegawa, G. Heinrich, A. Traunecker, 1984, The Journal of experimental medicine.

Peptide contributes to the specificity of positive selection of CD8+ T cells in the thymus

S. Tonegawa, T. Schumacher, H. Ploegh, 1993, Cell.

Nobel laureates' letter to President Bush.

J. D. Watson, D. Hubel, T. Wiesel, 2001, The Washington post.

Hippocampal CA3 Output Is Crucial for Ripple-Associated Reactivation and Consolidation of Memory

Susumu Tonegawa, Thomas J. McHugh, Derek L. Buhl, 2009, Neuron.

Identification of D segments of immunoglobulin heavy-chain genes and their rearrangement in T lymphocytes

S. Tonegawa, Y. Kurosawa, H. Sakano, 1981, Nature.

Cloning of an immunoglobulin variable region gene from mouse embryo.

S. Tonegawa, N. Hozumi, C. Brack, 1977, Proceedings of the National Academy of Sciences of the United States of America.

Ordered rearrangement of immunoglobulin heavy chain variable region segments.

F. Alt, S. Tonegawa, R. Coffman, 1984, The EMBO journal.

An unusual clonotypic determinant on a cytotoxic T lymphocyte line is encoded by an immunoglobulin heavy chain variable region gene.

S. Tonegawa, D. Ucker, Y. Kurasawa, 1985, Journal of immunology.

Transcription of the SV40 Genome in Transformed Cells and during Lytic Infection

S. Tonegawa, R. Dulbecco, G. Walter, 1970 .

Identification and nucleotide sequence of a diversity DNA segment (D) of immunoglobulin heavy-chain genes

S. Tonegawa, Y. Kurosawa, H. Sakano, 1981, Nature.

A Complete Immunoglobulin Gene Is Created by Somatic Recombination

Susumu Tonegawa, S. Tonegawa, Christine Brack, 2004 .

A complete immunoglobulin gene is created by somatic recombination

Susumu Tonegawa, S. Tonegawa, Christine Brack, 1978, Cell.

The role of DNA rearrangement and alternative RNA processing in the expression of immunoglobulin delta genes

S. Tonegawa, R. Maki, M. Wabl, 1981, Cell.

DNA clones containing mouse immunoglobulin kappa chain genes isolated by in vitro packaging into phage lambda coats.

S. Tonegawa, B. Hohn, C. Brack, 1978, Proceedings of the National Academy of Sciences of the United States of America.

Junctional sequences of T cell receptor γδ genes: Implications for γδ T cell lineages and for a novel intermediate of V-(D)-J joining

Susumu Tonegawa, Marc Bonneville, S. Tonegawa, 1989, Cell.

Reiteration frequency of immunoglobulin light chain genes: further evidence for somatic generation of antibody diversity.

S. Tonegawa, 1976, Proceedings of the National Academy of Sciences of the United States of America.

Tγ protein is expressed on murine fetal thymocytes as a disulphide-linked heterodimer

S. Tonegawa, M. Heller, Kouichi Ito, 1987, Nature.

DNA sequences of the joining regions of mouse lambda light chain immunoglobulin genes.

S. Tonegawa, B. Blomberg, 1982, Proceedings of the National Academy of Sciences of the United States of America.

Why do mature CNS neurons of mammals fail to re-establish connections following injury–functions of Bcl-2

S. Tonegawa, D. Chen, 1998, Cell Death and Differentiation.

Somatic Generation of Immune Diversity (Nobel Lecture)

S. Tonegawa, 1988 .

Somatic generation of immune diversity

Susumu Tonegawa, S. Tonegawa, 1988 .

Linkage of the four gamma subclass heavy chain genes.

S. Tonegawa, A. Traunecker, W. Roeder, 1981, Proceedings of the National Academy of Sciences of the United States of America.

Recognition of MHC TL Gene Products by γδ T Cells

S. Tonegawa, M. Bonneville, L. Kaer, 1991, Immunological reviews.

On somatic recombination in the central nervous system of transgenic mice.

S. Tonegawa, A. Graybiel, M. Katsuki, 1992, Science.

RAG-l-Deficient Mice Have No Mature 8 and T Lymphocytes

S. Tonegawa, K. Herrup, P. Mombaerts, 1992 .

Positive selection of γδ T cells

S. Tonegawa, A. Coutinho, J. Lafaille, 1990 .

Diversity of γδ T-cell receptors on murine intestinal intraepithelial lymphocytes

S. Tonegawa, M. Bonneville, Y. Takagaki, 1989, Nature.

Chromosomal locations of the murine T-cell receptor alpha-chain gene and the T-cell gamma gene.

S. Tonegawa, C. Disteche, F. Ruddle, 1985, Science.

Limited diversity of the rearranged T-cell γ gene

S. Tonegawa, D. Kranz, M. Heller, 1985, Nature.

Diversity and joining segments of mouse immunoglobulin heavy chain genes are closely linked and in the same orientation: implications for the joining mechanism.

S. Tonegawa, C. Wood, 1983, Proceedings of the National Academy of Sciences of the United States of America.

Organization, structure, and assembly of immunoglobulin heavy chain diversity DNA segments

S. Tonegawa, Y. Kurosawa, 1982, The Journal of experimental medicine.

Immunoglobulin gene rearrangement in immature B cells.

S. Tonegawa, J. Kearney, C. Paige, 1980, Science.

Characterization of a mouse DNA clone containing an immunoglobulin variable region gene.

S. Tonegawa, V. Pirrotta, N. Hozumi, 1978, Nucleic acids research.

Variable and constant parts of the immunoglobulin light chain gene of a mouse myeloma cell are 1250 nontranslated bases apart.

S. Tonegawa, C. Brack, 1977, Proceedings of the National Academy of Sciences of the United States of America.

Somatic changes in the content and context of immunoglobulin genes.

S. Tonegawa, G. Matthyssens, N. Hozumi, 1977, Cold Spring Harbor symposia on quantitative biology.

Conditional calcineurin knockout mice exhibit multiple abnormal behaviors related to schizophrenia

Hongkui Zeng, Susumu Tonegawa, Marc G Caron, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Cell type-specific genetic and optogenetic tools reveal novel hippocampal CA 2 circuits

Michele Pignatelli, Susumu Tonegawa, Hae-Yoon Jung, 2014 .

Activation of the c-myc gene by translocation: a model for translational control.

W. S. Hayward, S. Tonegawa, A. Hayday, 1983, Proceedings of the National Academy of Sciences of the United States of America.

T cell receptor δ gene mutant mice: Independent generation of αβ T cells and programmed rearrangements of γδ TCR genes

Susumu Tonegawa, Shigeyoshi Itohara, Alan R. Clarke, 1993, Cell.

Development and selection of gamma delta T cells.

S. Tonegawa, W. Haas, 1992, Current opinion in immunology.

Hippocampal Neurons Express a Calcineurin-Activated Adenylyl Cyclase

S. Tonegawa, D. Storm, G. Chan, 2005, The Journal of Neuroscience.

Evidence for association of schizophrenia with genetic variation in the 8p21.3 gene, PPP3CC, encoding the calcineurin gamma subunit

Susumu Tonegawa, Maria Karayiorgou, Tsuyoshi Miyakawa, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Alteration of a polyclonal to an oligoclonal immune response to cecal aerobic bacterial antigens in TCR alpha mutant mice with inflammatory bowel disease.

S. Tonegawa, E. Mizoguchi, A. Bhan, 1996, International immunology.

TAP1 mutant mice are deficient in antigen presentation, surface class I molecules, and CD4−8+ T cells

S. Tonegawa, H. Ploegh, L. Kaer, 1992, Cell.

Repertoire‐Determining Role of Peptide in the Positive Selection of CD8+ T cells

S. Tonegawa, T. Schumacher, H. Ploegh, 1993, Immunological reviews.

TAP1-dependent peptide translocation in vitro is ATP dependent and peptide selective

S. Tonegawa, C. Janeway, T. Schumacher, 1993, Cell.

Differential roles of the dopamine 1-class receptors, D1R and D5R, in hippocampal dependent memory

S. Tonegawa, T. Kitamura, L. Sultzman, 2014, Proceedings of the National Academy of Sciences.

Dopamine D3 Receptor Mutant Mice Exhibit Increased Behavioral Sensitivity to Concurrent Stimulation of D1 and D2 Receptors

S. Tonegawa, A. Graybiel, F. J. White, 1997, Neuron.

Cellular responses to psychomotor stimulant and neuroleptic drugs are abnormal in mice lacking the D1 dopamine receptor.

A M Graybiel, S. Tonegawa, A. Graybiel, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Blockade of transgenic gamma delta T cell development in beta 2‐microglobulin deficient mice.

S. Tonegawa, R. Jaenisch, P. Pereira, 1992, The EMBO journal.

Presentation of endogenous viral proteins in association with major histocompatibility complex class II: On the role of intracellular compartmentalization, invariant chain and the TAP transporter system

S. Tonegawa, R. Zinkernagel, A. Oxenius, 1995, European journal of immunology.

Cre/loxP recombination‐activated neuronal markers in mouse neocortex and hippocampus

Susumu Tonegawa, S. Tonegawa, Z. J. Huang, 2002, Genesis.

Recognition of the product of a novel MHC TL region gene (27b) by a mouse γδ T cell receptor

S. Tonegawa, M. Bonneville, L. Kaer, 1990, Cell.

Somatic Mutation Creates Diversity in Major Group of Mouse Immunoglobulin K Chains the Light

S. Tonegawa, G. Heinrich, Elsasser Th, 2022 .

Contribution of alpha/beta and gamma/delta T lymphocytes to immunity against Mycobacterium bovis bacillus Calmette Guérin: studies with T cell receptor-deficient mutant mice.

S. Tonegawa, S. Kaufmann, P. Mombaerts, 1995, European journal of immunology.

Monoclonal antibodies specific to native murine T-cell receptor gamma delta: analysis of gamma delta T cells during thymic ontogeny and in peripheral lymphoid organs.

S. Tonegawa, S. Itohara, R. Kubo, 1989, Proceedings of the National Academy of Sciences of the United States of America.

Fear memories require protein synthesis in the amygdala for reconsolidation after retrieval

S. Tonegawa, S. Itohara, R. Erzurumlu, 2022 .

Recognition of a self major histocompatibility complex TL region product by gamma delta T-cell receptors.

S. Tonegawa, S. Itohara, C. Janeway, 1989, Proceedings of the National Academy of Sciences of the United States of America.

Secondary, tertiary, and quaternary structure of T-cell-specific immunoglobulin-like polypeptide chains.

S. Tonegawa, J. Novotný, D. Kranz, 1986, Proceedings of the National Academy of Sciences of the United States of America.

Thalamic Cav3.1 T-type Ca2+ channel plays a crucial role in stabilizing sleep.

Susumu Tonegawa, Matthew P. Anderson, Edmund M Talley, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Diversity of murine gamma genes and expression in fetal and adult T lymphocytes

S. Tonegawa, J. Heilig, 1986, Nature.

Revised nomenclature of mouseH-2 genes

S. Tonegawa, H. Mcdevitt, C. Benoist, 2005, Immunogenetics.

Nomenclature Revised nomenclature of mouse B-2 genes

L. Hood, S. Tonegawa, H. Mcdevitt, 1993 .

Potential Biomarker for Human Uterine Leiomyosarcoma

H. Aburatani, S. Tonegawa, Y. Kanai, 2014, Journal of clinical medicine research.

Candidate Molecules and ki-67/MIB1 as Novel Diagnostic Biomarker for Human Uterine Mesenchymal Tumors

S. Tonegawa, N. Yaegashi, I. Konishi, 2013 .

A Novel Diagnostic Marker: Proteasome LMP2/1i-Differential Expression in Human Uterus Mesenchymal Tumor

S. Tonegawa, N. Yaegashi, T. Shiozawa, 2013 .

Differences in the level of expression of class I major histocompatibility complex proteins on thymic epithelial and dendritic cells influence the decision of immature thymocytes between positive and negative selection.

S. Tonegawa, H. Eisen, S Tonegawa, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Transgenic brain-derived neurotrophic factor expression causes both anxiogenic and antidepressant effects

S. Tonegawa, A. Govindarajan, S. Chattarji, 2006, Proceedings of the National Academy of Sciences.

Diversity of gamma delta T-cell receptors on murine intestinal intra-epithelial lymphocytes.

S. Tonegawa, M. Bonneville, Y. Takagaki, 1989, Nature.

Recognition of the product of a novel MHC TL region gene (27b) by a mouse gamma delta T cell receptor.

S. Tonegawa, M. Bonneville, L. Van Kaer, 1990, Cell.

Selection of preconfigured cell assemblies for representation of novel spatial experiences

Susumu Tonegawa, George Dragoi, G. Dragoi, 2014, Philosophical Transactions of the Royal Society B: Biological Sciences.

Genetic neuroscience of mammalian learning and memory.

Susumu Tonegawa, Matthew A Wilson, M. Wilson, 2003, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.

That great time in Basel

S. Tonegawa, 2004, Cell.

Evidence for somatic generation of antibody diversity.

S. Tonegawa, C. Steinberg, S. Dube, 1974, Proceedings of the National Academy of Sciences of the United States of America.

CD4+ T Cells Prevent Spontaneous Experimental Autoimmune Encephalomyelitis in Anti–Myelin Basic Protein T Cell Receptor Transgenic Mice

S. Tonegawa, F. Van de Keere, 1998, The Journal of experimental medicine.

What is memory? The present state of the engram

Fred H. Gage, Michele Pignatelli, Tobias Bonhoeffer, 2016, BMC Biology.

Identification and Manipulation of Memory Engram Cells.

Roger L Redondo, Susumu Tonegawa, Xu Liu, 2014, Cold Spring Harbor symposia on quantitative biology.

Altered peptidase and viral-specific T cell response in LMP2 mutant mice.

S. Tonegawa, A. Goldberg, M. Eichelberger, 1994, Immunity.

Involvement of proteasome β1i subunit, LMP2, on development of uterin leiomyosarcma

H. Aburatani, S. Tonegawa, Y. Kanai, 2011, North American journal of medical sciences.

Molecular Approach to Uterine Leiomyosarcoma: LMP2-Deficient Mice as an Animal Model of Spontaneous Uterine Leiomyosarcoma

S. Tonegawa, Y. Kanai, N. Hiraoka, 2011, Sarcoma.

Molecular Approach to Uterine Leiomyosarcoma : LMP 2-Deficient Mice as an Animal Model of Spontaneous Uterine Leiomyosarcoma Citation

S. Tonegawa, Y. Kanai, N. Hiraoka, 2011 .

Mice-lacking LMP2, immuno-proteasome subunit, as an animal model of spontaneous uterine leiomyosarcoma

S. Tonegawa, Y. Kanai, N. Hiraoka, 2010, Protein & Cell.

Positive selection of self- and alloreactive CD8+ T cells in Tap-1 mutant mice.

S. Tonegawa, H. Ljunggren, L. Kaer, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Tap‐1変異マウスにおける自己およびアロ反応性CD8+T細胞の正の選択

S. Tonegawa, J. Forman, J. AldrichC., 1994 .

In Vivo Two-Photon Imaging Reveals a Role of Arc in Enhancing Orientation Specificity in Visual Cortex

Susumu Tonegawa, Mriganka Sur, Chengcheng Hu, 2006, Cell.

Increase in Positive Selection o f C D 8 + T Cells in TAPl-Mutant Mice by Human / ~ 2-Microglobul ln Transgene By Hisse

S. Tonegawa, H. Ploegh, L. Kaer, 2003 .

Increase in positive selection of CD8+ T cells in TAP1-mutant mice by human beta 2-microglobulin transgene

S. Tonegawa, H. Ploegh, A. Berns, 1995, The Journal of experimental medicine.

Increase in Positive Selection of CD8 + T Cells in TAPl-Mutant Mice by Human/~2-Microgl obulln Transgene By Hisse Martien van Santen,* Aaron Woolsey,*

S. Tonegawa, H. Ploegh, L. Kaer, 1995 .

Incorrect attribution of peptide source

S. Tonegawa, C. Janeway, T. Schumacher, 1993, Cell.

Visual cortex is rescued from the effects of dark rearing by overexpression of BDNF

L. Maffei, S. Tonegawa, Z. J. Huang, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Decreased ethanol sensitivity and tolerance development in gamma-protein kinase C null mutant mice is dependent on genetic background.

A. C. Collins, S. Tonegawa, A. Collins, 1999, Alcoholism, clinical and experimental research.

PAK Inactivation Impairs Social Recognition in 3xTg-AD Mice without Increasing Brain Deposition of Tau and Aβ

S. Tonegawa, D. Bennett, Y. de Koninck, 2013, The Journal of Neuroscience.

PAK Inactivation Impairs Social Recognition in 3 xTg-AD Mice without Increasing Brain Deposition of Tau and A Citation

S. Tonegawa, D. Bennett, Y. Koninck, 2013 .

An Important Role of Neural Activity-Dependent CaMKIV Signaling in the Consolidation of Long-Term Memory

M. Wilson, S. Tonegawa, Linus D. Sun, 2001, Cell.

The role of engram cells in the systems consolidation of memory

Mark D. Morrissey, S. Tonegawa, T. Kitamura, 2018, Nature Reviews Neuroscience.

A Role for Calcium-Permeable AMPA Receptors in Synaptic Plasticity and Learning

Brian J. Wiltgen, S. Tonegawa, S. Heinemann, 2010, PloS one.

Silent memory engrams as the basis for retrograde amnesia

Dheeraj S Roy, Lillian M Smith, Susumu Tonegawa, 2017, Proceedings of the National Academy of Sciences.

Impaired Hippocampal Ripple-Associated Replay in a Mouse Model of Schizophrenia

Matthew A. Wilson, Susumu Tonegawa, Heydar Davoudi, 2013, Neuron.

Conjunctive input processing drives feature selectivity in hippocampal CA1 neurons

Susumu Tonegawa, Katie C Bittner, Christine Grienberger, 2015, Nature Neuroscience.

Development of schemas revealed by prior experience and NMDA receptor knock-out

George Dragoi, Susumu Tonegawa, G. Dragoi, 2013, eLife.

Hippocampal neurons represent events as transferable units of experience

Chen Sun, Susumu Tonegawa, Wannan Yang, 2020, Nature Neuroscience.

Acceleration of visually cued conditioned fear through the auditory pathway

J. R. Newton, M. Sur, S. Tonegawa, 2004, Nature Neuroscience.

Crucial role for CA2 inputs in the sequential organization of CA1 time cells supporting memory

S. Tonegawa, C. MacDonald, 2021, Proceedings of the National Academy of Sciences.

Spatial exploration is required for the formation of contextual fear memory.

S. Tonegawa, T. McHugh, 2007, Behavioral neuroscience.

Distinct Neural Circuits for the Formation and Retrieval of Episodic Memories

Chen Sun, Susumu Tonegawa, Atsushi Yoshiki, 2017, Cell.

NMDA signaling in CA1 mediates selectively the spatial component of episodic memory.

Howard Eichenbaum, Susumu Tonegawa, Thomas J McHugh, 2012, Learning & memory.

CA1 pyramidal cells organize an episode by segmented and ordered events

Susumu Tonegawa, Chen Sun, Wannan Yang, 2019, bioRxiv.

Amygdala Reward Neurons Form and Store Fear Extinction Memory

X. Zhang, S. Tonegawa, Joshua Kim, 2019, Neuron.

Identification and optogenetic manipulation of memory engrams in the hippocampus

Susumu Tonegawa, Xu Liu, Steve Ramirez, 2014, Front. Behav. Neurosci..

Junctional sequences of T cell receptor gamma delta genes: implications for gamma delta T cell lineages and for a novel intermediate of V-(D)-J joining.

S. Tonegawa, M. Bonneville, J. Lafaille, 1989, Cell.

Importance of diagnostic methods for round ligament leiomyomas in clinical practice

S. Tonegawa, N. Yaegashi, I. Konishi, 2023, Quantitative imaging in medicine and surgery.

Organization of immunoglobulin genes.

S. Tonegawa, V. Pirrotta, N. Hozumi, 1978, Cold Spring Harbor symposia on quantitative biology.

Synaptic plasticity, place cells and spatial memory: study with second generation knockouts

Susumu Tonegawa, Matthew A Wilson, M. Wilson, 1997, Trends in Neurosciences.

A functional γ gene formed from known γ-gene segments is not necessary for antigen-specific responses of murine cytotoxic T lymphocytes

S. Tonegawa, D. Kranz, H. Eisen, 1986, Nature.

Gamma delta T cells differentiate into a functional but nonproliferative state during a normal immune response.

S. Tonegawa, P. Pereira, K. Migita, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Self-tolerance to transgenic γδ T cells by intrathymic inactivation

S. Tonegawa, S. Itohara, M. Bonneville, 1990, Nature.

Ejaculatory abnormalities in mice with targeted disruption of the gene for heme oxygenase-2

S. Tonegawa, S. Snyder, L. Schramm, 1998, Nature Medicine.

Psychotomimetic effects of drugs--a common pathway to schizophrenia?

S. Tonegawa, D. Gerber, 2004, The New England journal of medicine.

PKC gamma mutant mice exhibit mild deficits in spatial and contextual learning.

J J Kim, S. Tonegawa, J. J. Kim, 1993, Cell.

Modified hippocampal long-term potentiation in PKC gamma-mutant mice.

C F Stevens, S. Tonegawa, Y. Goda, 1993, Cell.

Limbic epilepsy in transgenic mice carrying a Ca2+/calmodulin-dependent kinase II alpha-subunit mutation.

S. Tonegawa, Y. Watanabe, J. McNamara, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Mutant mice lacking the gamma isoform of protein kinase C show decreased behavioral actions of ethanol and altered function of gamma-aminobutyrate type A receptors.

S. Tonegawa, R. Harris, A. Abeliovich, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Hybridization studies with an antibody heavy chain mRNA

S. Tonegawa, A. Bernardini, 1974, FEBS letters.

Reiteration frequency of antibody genes Studies with κ‐chain mRNA

S. Tonegawa, C. Steinberg, B. Weimann, 1974, FEBS letters.

Optogenetics 3.0

S. Tonegawa, Xu Liu, 2010, Cell.

Lack of Self-Administration of Cocaine in Dopamine D1 Receptor Knock-Out Mice

S. Tonegawa, S. B. Caine, G. Koob, 2007, The Journal of Neuroscience.

T-cell gamma gene is allelically but not isotypically excluded and is not required in known functional T-cell subsets.

S. Tonegawa, J. Heilig, 1987, Proceedings of the National Academy of Sciences of the United States of America.

Candidate molecules as diagnostic biomarker for human uterine mesenchymal tumors

S. Tonegawa, Y. Kanai, N. Yaegashi, 2020 .

Somatic mutations in IFN-γ-Signal molecules in human uterine leiomyosarcoma

H. Aburatani, S. Tonegawa, Y. Kanai, 2018, Annals of Biotechnology.

B Lineage-Specific Interactions of an Innnunogiobulin Enhancer with Cellular Factors in vivo STOR

S. Tonegawa, A. Ephrussi, 2011 .

CA3 NMDA receptors are required for experience‐dependent shifts in hippocampal activity

S. Tonegawa, S. Small, K. Kent, 2007, Hippocampus.

Gamma delta T cells contribute to immunity against the liver stages of malaria in alpha beta T-cell-deficient mice.

S. Tonegawa, P. Mombaerts, M. Tsuji, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Differentiation of forebrain and hippocampal dopamine 1‐class receptors, D1R and D5R, in spatial learning and memory

S. Tonegawa, Joshua Sariñana, 2015, Hippocampus.

Presynaptic m1 muscarinic receptors are necessary for mGluR long-term depression in the hippocampus

Susumu Tonegawa, Thomas J McHugh, S. Tonegawa, 2010, Proceedings of the National Academy of Sciences.

Brain‐derived neurotrophic factor over‐expression in the forebrain ameliorates Huntington’s disease phenotypes in mice

Susumu Tonegawa, S. Tonegawa, Baoji Xu, 2008, Journal of neurochemistry.

Differential gene expression between sensory neocortical areas: potential roles for Ten_m3 and Bcl6 in patterning visual and somatosensory pathways.

M. Sur, S. Tonegawa, C. Leamey, 2007, Cerebral cortex.

CA3 NMDA receptors are required for the rapid formation of a salient contextual representation

Susumu Tonegawa, S. Tonegawa, T. McHugh, 2009, Hippocampus.

Hippocampal CA1-region-restricted knockout of NMDAR1 gene disrupts synaptic plasticity, place fields, and spatial learning.

K. I. Blum, M. Wilson, S. Tonegawa, 1996, Cold Spring Harbor symposia on quantitative biology.

Cytotoxic and interferon gamma-producing activities of gamma delta T cells in the mouse intestinal epithelium are strain dependent.

S. Tonegawa, S. Kaufmann, A. Abeliovich, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Rearrangement and expression of Vγ1, Vγ2 and Vγ3 TCR γ genes in C57BL/6 mice

S. Tonegawa, P. Pereira, A. Coutinho, 1996 .

Identification of a T-cell-specific enhancer at the locus encoding T-cell antigen receptor gamma chain.

S. Tonegawa, D. Kappes, C. Browne, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Manipulating memory in space and time

Dheeraj S Roy, Susumu Tonegawa, Dheeraj S. Roy, 2017, Current Opinion in Behavioral Sciences.

Title : Memory engram Cells Have Come of Age

S. Tonegawa, Xu Liu, S. Ramirez, 2015 .

Lack of kainic acid‐induced gamma oscillations predicts subsequent CA1 excitotoxic cell death

M. Wilson, S. Tonegawa, K. Nakazawa, 2009, The European journal of neuroscience.

Hippocampal lesions impair contextual fear conditioning in two strains of mice.

S. Tonegawa, J. J. Kim, C. Chen, 1996, Behavioral neuroscience.

Rearrangement and expression of Vzeta1, Vzeta2 and Vzeta3 TCR zeta genes in C57BL/6 mice.

S. Tonegawa, P. Pereira, A. Coutinho, 1996, International Immunology.

Expression of the T-cell receptor gamma-chain gene products on the surface of peripheral T cells and T-cell blasts generated by allogeneic mixed lymphocyte reaction.

S. Tonegawa, K. Shitara, W. Haser, 1987, Proceedings of the National Academy of Sciences of the United States of America.

Impaired synapse elimination during cerebellar development in PKC gamma mutant mice.

S. Tonegawa, M. Kano, K. Hashimoto, 1995, Cell.

Biological Analyses for Characterization of the Uterine Sarcoma Using Mouse Model

S. Tonegawa, Y. Kanai, N. Yaegashi, 2017 .

t Brain-Derived Neurotrophic Factor Overexpression Induces Precocious Critical Period in Mouse Visual Cortex

Susumu Tonegawa, Michael P. Stryker, Z. Josh Huang, 1999, The Journal of Neuroscience.

Distinct preplay of multiple novel spatial experiences in the rat

George Dragoi, Susumu Tonegawa, G. Dragoi, 2013, Proceedings of the National Academy of Sciences.

Distribution of thymocytes expressing gamma delta receptors in the murine thymus during development.

S. Tonegawa, S. Itohara, S. Hosier, 1990, Journal of immunology.

Amino acid substitutions in the floor of the putative antigen-binding site of H-2T22 affect recognition by a gamma delta T-cell receptor.

S. Tonegawa, L. Van Kaer, Y. Ichikawa, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Self-tolerance to transgenic gamma delta T cells by intrathymic inactivation.

S. Tonegawa, S. Itohara, M. Bonneville, 1990, Nature.

alpha beta and gamma delta T cells in the immune response to the erythrocytic stages of malaria in mice.

S. Tonegawa, P. Mombaerts, J. Langhorne, 1995, International immunology.

V and C parts of immunoglobulin kappa-chain genes are separate in myeloma.

S. Tonegawa, G. Matthyssens, 1978, Nature.

Competition from newborn granule cells does not drive axonal retraction of silenced old granule cells in the adult hippocampus

Susumu Tonegawa, Chris J. McBain, Toshiaki Nakashiba, 2012, Front. Neural Circuits.

The Study of Somatic Mutations in Human Uterine Leiomyosarcoma

H. Aburatani, S. Tonegawa, Y. Kanai, 2017 .

Cytotoxic and interferon y-producing activities of y6T cells in the mouse intestinal epithelium are strain dependent

S. Tonegawa, A. Abeliovich, H. Ishikawa, 2005 .

Pathobiology of Human Uterine Leiomyosarcoma for Development of Novel Diagnosis and Clinical Therapy

S. Tonegawa, Y. Kanai, N. Yaegashi, 2017 .

CD3 delta deficiency arrests development of the alpha beta but not the gamma delta T cell lineage.

S. Tonegawa, B. Alarcón, A. De La Hera, 1997, The EMBO journal.

Biological Significance of the Proteasome Subunit LMP2/1i as a Tumor Suppressor in Human Uterine Leiomyosarcoma

H. Aburatani, S. Tonegawa, Y. Kanai, 2012 .

A diagnostic biomarker: differential expression of LMP2/β1i in human uterine neoplasms

H. Aburatani, S. Tonegawa, Y. Kanai, 2014 .

Proteasome Subunit LMP 2 / b 1 i As a Biomarker for Human Uterine Mesenchymal Tumors

H. Aburatani, S. Tonegawa, Y. Kanai, 2013 .

Deficient Hippocampal Long-Term Potentiation in oCa cium-Calmodulin Kinase Mutant Mice

Alcino J. Silva, S. Tonegawa, C. Stevens, 2009 .

Abstracts of the 15th Annual Meeting of the Israel Society for Neuroscience Eilat, Israel, December 3–5, 2006

Leslie G. Ungerleider, D. Amit, H. Seung, 2006, Neural Plasticity.

Intermediates in the assembly of phi X174.

S. Tonegawa, M. Hayashi, 1970, Journal of molecular biology.

Cortex Are Independent of Apical Dendrite Bundling Synaptic Connections between Layer 5B Pyramidal Neurons in Mouse Somatosensory

S. Nelson, M. Sur, B. Sakmann, 2008 .

Dentate Gyrus NMDA Receptors Mediate Rapid Pattern Separation in the Hippocampal Network

M. Wilson, S. Tonegawa, M. Fanselow, 2007, Science.

Importance of diagnostic methods for round ligament leiomyomas in clinical practice

S. Tonegawa, N. Yaegashi, I. Konishi, 2023, Quantitative imaging in medicine and surgery.

Impaired Hippocampal Representation of Space in CA1-Specific NMDAR1 Knockout Mice

K. I. Blum, M. Wilson, S. Tonegawa, 1996, Cell.

Molecular approaches of sarcomagenesis for establishment of clinical therapy

S. Tonegawa, Y. Kanai, N. Yaegashi, 2016 .

Erratum: NMDA receptor-dependent ocular dominance plasticity in adult visual cortex (Neuron (June 19, 2003) 38 (977-985))

M. Bear, S. Tonegawa, K. Nakazawa, 2003, Neuron.

The Ins and Outs of Hippocampal Circuits

Susumu Tonegawa, Thomas J. McHugh, S. Tonegawa, 2008, Neuron.

Molecular and Circuit Mechanisms for Hippocampal Learning

S. Tonegawa, T. McHugh, 2008 .

The human T-cell receptor alpha-chain gene maps to chromosome 14.

S. Tonegawa, P. Goodfellow, M. Collins, 1985, Nature.

Peptide length and sequence specificity of the mouse TAP1/TAP2 translocator

S. Tonegawa, P. A. Peterson, T. Schumacher, 1994, The Journal of experimental medicine.

Pillars article: High incidence of spontaneous autoimmune encephalomyelitis in immunodeficient anti-myelin basic protein T cell receptor transgenic mice. Cell. 1994. 78: 399-408.

S. Tonegawa, M. Katsuki, K. Nagashima, 2013, Journal of immunology.

Silent memory engrams as the basis for retrograde amnesia

Dheeraj S. Roy, S. Tonegawa, S. Muralidhar, 2017, Proceedings of the National Academy of Sciences.

Entorhinal Cortex Layer III Input to the Hippocampus Is Crucial for Temporal Association Memory

Alexander J. Rivest, S. Tonegawa, Junghyup Suh, 2011, Science.

Memory engram storage and retrieval

Dheeraj S. Roy, S. Tonegawa, T. Ryan, 2015, Current Opinion in Neurobiology.

Ventral CA1 neurons store social memory

Dheeraj S. Roy, S. Tonegawa, S. Itohara, 2016, Science.

Distinct Neural Circuits for the Formation and Retrieval of Episodic Memories

Dheeraj S. Roy, Sachie K. Ogawa, S. Tonegawa, 2017, Cell.

The role of engram cells in the systems consolidation of memory

Takashi Kitamura, Mark D Morrissey, Susumu Tonegawa, 2018, Nature Reviews Neuroscience.

gamma/delta T cell-deficient mice have impaired mucosal immunoglobulin A responses

S. Tonegawa, J. Mcghee, H. Kiyono, 1996, The Journal of experimental medicine.

Pillars Article: Evidence for somatic rearrangement of immunoglobulin genes coding for variable and constant regions

S. Tonegawa, N. Hozumi, 2004 .

Differentiation of Immunoglobulin Genes

S. Tonegawa, N. Hozumi, 1976 .

TRANSGENIC MICE DEMONSTRATE THAT EPITHELIAL HOMING OF y/b T CELLS IS DETERMINED BY CELL LINEAGES INDEPENDENT OF T CELL RECEPTOR SPECIFICITY

S. Tonegawa, S. Itohara, M. Katsuki, 2003 .

Lack of kainic acid‐induced gamma oscillations predicts subsequent CA1 excitotoxic cell death

M. Wilson, S. Tonegawa, K. Nakazawa, 2009, The European journal of neuroscience.

Cell type-specific genetic and optogenetic tools reveal novel hippocampal CA 2 circuits

Alexander J. Rivest, S. Tonegawa, Junghyup Suh, 2014 .