D. Crothers

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Climate change and the integrity of science.

G. B. Dalrymple, W. R. Gardner, R. Rivest, 2010, Science.

Improved estimation of secondary structure in ribonucleic acids.

D. Crothers, I. Tinoco, O. Uhlenbeck, 1973, Nature: New biology.

Free energy of imperfect nucleic acid helices. I. The bulge defect.

D. Crothers, T. R. Fink, J. Gralla, 1973, Journal of molecular biology.

Does 5S RNA function by a switch between two secondary structures?

D. Crothers, H. Weidner, R. Yuan, 1977, Nature.

Free energy of imperfect nucleic acid helices. II. Small hairpin loops.

D. Crothers, J. Gralla, 1973, Journal of molecular biology.

Free energy of imperfect nucleic acid helices. 3. Small internal loops resulting from mismatches.

D. Crothers, J. Gralla, Donald M. Crothers, 1973, Journal of molecular biology.

Is there a discriminator site in transfer RNA?

D. Crothers, D. Söll, T. Seno, 1972, Proceedings of the National Academy of Sciences of the United States of America.

Kinetics of the daunomycin--DNA interaction.

D. Crothers, J. Chaires, N. Dattagupta, 1985, Biochemistry.

Equilibria and kinetics of lac repressor-operator interactions by polyacrylamide gel electrophoresis.

D. Crothers, M. Fried, M. Fried, 1981, Nucleic acids research.

29 Structural and binding properties of DNA response elements bound to p53 proteins and the role of spacer sequences in p53-DNA interactions

D. Crothers, M. Kitayner, Z. Shakked, 2015, Journal of biomolecular structure & dynamics.

Transmission of allosteric effects in DNA

D. Crothers, N. Dattagupta, M. Hogan, 1979, Nature.

Transmission of long-range effects in DNA.

D. Crothers, M. Fried, 1983, Cold Spring Harbor symposia on quantitative biology.

Intrinsically bent DNA.

D M Crothers, D. Crothers, T. Haran, 1990, The Journal of biological chemistry.

DNA bending, flexibility, and helical repeat by cyclization kinetics.

D. Crothers, J. Kahn, J. Drak, 1992, Methods in enzymology.

Nucleic Acids: Structures, Properties, and Functions

D. Crothers, I. Tinoco, V. Bloomfield, 2000 .

The kinetics of ligand binding by an adenine-sensing riboswitch.

D. Crothers, R. Breaker, M. Cheah, 2005, Biochemistry.

The speed of RNA transcription and metabolite binding kinetics operate an FMN riboswitch.

D. Crothers, R. Breaker, W. Winkler, 2005, Molecular cell.

Bent helix formation between RNA hairpins with complementary loops.

D. Crothers, J. Marino, R. Gregorian, 1995, Science.

The molecular mechanism of thermal unfolding of Escherichia coli formylmethionine transfer RNA.

D. Crothers, C. W. Hilbers, R. Shulman, 1974, Journal of molecular biology.

Solution structural studies of the Ag(I)-DNA complex.

D. Crothers, N. Dattagupta, 1981, Nucleic acids research.

The solution structure of an RNA loop-loop complex: the ColE1 inverted loop sequence.

D. Crothers, A. J. Lee, 1998, Structure.

The dimensions of DNA in solution.

J. G. Elias, D. Crothers, M. Mandelkern, 1981, Journal of molecular biology.

DNA sequence determinants of CAP-induced bending and protein binding affinity

Donald M. Crothers, D. Crothers, M. Gartenberg, 1988, Nature.

The locus of sequence-directed and protein-induced DNA bending

Hen-Ming Wu, Donald M. Crothers, D. Crothers, 1984, Nature.

DNA bending at adenine · thymine tracts

Hen-Ming Wu, Donald M. Crothers, D. Crothers, 1986, Nature.

A stressed intermediate in the formation of stably initiated RNA chains at the Escherichia coli lac UV5 promoter.

D. Crothers, D. Straney, 1987, Journal of molecular biology.

Intermediates in transcription initiation from the E. coli lac UV5 promoter

Donald M. Crothers, D. Crothers, D. Straney, 1985, Cell.

SIMPLIFIED ROTATING CYLINDER VISCOMETER FOR DNA.

D M Crothers, D. Crothers, B. Zimm, 1962, Proceedings of the National Academy of Sciences of the United States of America.

Determining RNA solution structure by segmental isotopic labeling and NMR: application to Caenorhabditis elegans spliced leader RNA 1.

D. Crothers, J. Xu, J. Lapham, 1996, Proceedings of the National Academy of Sciences of the United States of America.

31P nmr spin‐lattice relaxation studies of deoxyoligonucleotides

D. Crothers, P. Davanloo, I. Armitage, 1979 .

Interactions of heteroaromatic compounds with nucleic acids. 1. The influence of heteroatoms and polarizability on the base specificity of intercalating ligands.

D. Crothers, W. Müller, 1975, European journal of biochemistry.

The position of site-directed cleavage of RNA using RNase H and 2'-O-methyl oligonucleotides is dependent on the enzyme source.

J. Steitz, D. Crothers, M. Shu, 1997, RNA.

Helical repeat and chirality effects on DNA gel electrophoretic mobility.

D. Crothers, J. Drak, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Singlet-singlet energy transfer studies of the internal organization of nucleosomes.

D. Crothers, C. Cantor, H. Eshaghpour, 1980, Biochemistry.

Influence of DNA-binding drugs on chromatin condensation.

D. Crothers, D. Sen, 1986, Biochemistry.

Simultaneous measurement of binding constants and unwinding angles by gel electrophoresis.

D. Crothers, S. Zeman, 2001, Methods in enzymology.

Simultaneous determination of helical unwinding angles and intrinsic association constants in ligand-DNA complexes: the interaction between DNA and calichearubicin B.

D. Crothers, S. Danishefsky, K. Depew, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Unfolding of 175-base-pair nucleosomes.

D. Crothers, N. Dattagupta, F. Schlessinger, 1982, Biochemistry.

Structural changes of nucleosomes in low-salt concentrations.

D. Crothers, N. Dattagupta, M. Hogan, 1979, Biochemistry.

Functional linkage in biomolecular systems

F. O. Schmitt, D. Crothers, D. Schneider, 1975 .

DNA-binding domains of Fos and Jun do not induce DNA curvature: an investigation with solution and gel methods.

D. Crothers, A. Sitlani, 1998, Proceedings of the National Academy of Sciences of the United States of America.

DNA cross-linking by intermediates in the mitomycin activation cascade.

D. Crothers, S. Danishefsky, C. Cera, 1989, Biochemistry.

DNA sequence specificity of mitomycin cross-linking.

D. Crothers, S. Woodson, S. Teng, 1989, Biochemistry.

Anthracycline antibiotics. Interaction with DNA and nucleosomes and inhibition of DNA synthesis.

D. Crothers, J. Chaires, N. Dattagupta, 1987, Biochemistry.

A bent helix in kinetoplast DNA.

D. Crothers, S. Levene, P. T. Englund, 1983, Cold Spring Harbor symposia on quantitative biology.

Higher order structure of chromatin: evidence from photochemically detected linear dichroism.

D. Crothers, D. Sen, S. Mitra, 1986, Biochemistry.

Kinin receptors on epithelial cells and smooth muscle of the trachea.

D. Crothers, K. Bhoola, C. Figueroa, 1989, Advances in experimental medicine and biology.

High-resolution transcription assay for probing drug-DNA interactions at individual drug sites.

D. Crothers, S. Cutts, C. Cullinane, 2001, Methods in enzymology.

An in vitro transcription assay for probing drug-DNA interactions at individual drug sites

D. Crothers, C. Cullinane, D. Phillips, 1998, Molecular biotechnology.

Equilibrium studies of ethidium--polynucleotide interactions.

D. Crothers, J. L. Bresloff, 1981, Biochemistry.

Comparative gel electrophoresis measurement of the DNA bend angle induced by the catabolite activator protein

D. Crothers, S. Zinkel, 1990, Biopolymers.

Rate of unwinding small DNA.

D. Crothers, R. J. Cohen, Donald M. Crothers, 1971, Journal of molecular biology.

Phased psoralen cross-links do not bend the DNA double helix.

D. Crothers, T. Haran, 1988, Biochemistry.

Sliding and intermolecular transfer of the lac repressor: kinetic perturbation of a reaction intermediate by a distant DNA sequence.

D. Crothers, T. Ruusala, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Conversion of B DNA between solution and fiber conformations.

D. Crothers, M. Mandelkern, N. Dattagupta, 1981, Proceedings of the National Academy of Sciences of the United States of America.

Upsetting the balance of forces in DNA.

D. Crothers, 1994, Science.

Comparison of Analyses of DNA Curvature

D. Crothers, Andrej Barbič, 2003, Journal of biomolecular structure & dynamics.

Studies of the optical properties of the proflavine–DNA complex

D. Crothers, Hsueh Jei Li, 1969 .

A proton magnetic resonance study of single-stranded and double-helical deoxyribooligonucleotides.

A. D. Cross, D. Crothers, 1971, Biochemistry.

Prediction of the stability of DNA triplexes.

D. Crothers, R. Roberts, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Orientation of nucleosomes and linker DNA in calf thymus chromatin determined by photochemical dichroism

D. Crothers, D. Sen, S. Mitra, 1984, Nature.

Molecular characterization of the GCN4-DNA complex.

D. Crothers, T. Steitz, C. Ampe, 1990, Proceedings of the National Academy of Sciences of the United States of America.

Solution structural studies of the A and Z forms of DNA.

D. Crothers, N. Dattagupta, H. M. Wu, 1981, Proceedings of the National Academy of Sciences of the United States of America.

Solution structural studies of chromatin fibers.

D. Crothers, M. Mandelkern, K. S. Lee, 1981, Biochemistry.

Transient electric dichroism studies of nucleosomal particles.

D. Crothers, N. Dattagupta, M. Hogan, 1978, Biochemistry.

Effects of DNA sequence and histone-histone interactions on nucleosome placement.

D. Crothers, T. E. Shrader, 1990, Journal of molecular biology.

Chemical determinants of DNA bending at adenine-thymine tracts.

D. Crothers, H. Koo, 1987, Biochemistry.

Ring closure probabilities for DNA fragments by Monte Carlo simulation.

D. Crothers, S. Levene, Donald M. Crothers, 1986, Journal of molecular biology.

Calibration of DNA curvature and a unified description of sequence-directed bending.

D. Crothers, H. Koo, 1988, Proceedings of the National Academy of Sciences of the United States of America.

The rate of DNA unwinding.

D. Crothers, H. Spatz, 1969, Journal of molecular biology.

Thermodynamic and kinetic properties of short RNA helices: the oligomer sequence AnGCUn.

D. Crothers, J. Gralla, J. Ravetch, 1974, Nucleic acids research.

Decreased imino proton exchange and base-pair opening in the IHF-DNA complex measured by NMR.

D. Crothers, J. Lapham, S. Yang, 1999, Journal of molecular biology.

THE KINETICS OF DNA DENATURATION.

D. Crothers, D M CROTHERS, Donald M. Crothers, 1964, Journal of molecular biology.

Nuclear magnetic resonance investigation of lysine–oligopeptides and a complex with d(pA)3pGpC(pT)3

D. Crothers, P. Davanloo, 1979 .

Electrostatic contributions to oligonucleotide transitions

C. DeLisi, D. Crothers, Charles Delisi, 1971, Biopolymers.

Preparation and characterization of monodisperse, cross-linked low molecular weight deoxyribonucleic acid.

D. Crothers, R. J. Cohen, 1970, Biochemistry.

Studies of the binding of actinomycin and related compounds to DNA.

D M Crothers, D. Crothers, W. Müller, 1968, Journal of molecular biology.

Predicting indirect readout effects in protein-DNA interactions.

Yongli Zhang, D. Crothers, Z. Shakked, 2004, Proceedings of the National Academy of Sciences of the United States of America.

DNA bend direction by phase sensitive detection

D. Crothers, S. Zinkel, 1987, Nature.

Bent helical structure in kinetoplast DNA.

D M Crothers, D. Crothers, S. Levene, 1982, Proceedings of the National Academy of Sciences of the United States of America.

RNA binding assays for Tat-derived peptides: implications for specificity.

D. Crothers, K. Weeks, Kevin M. Weeks, 1992, Biochemistry.

Studies on interaction of anthracycline antibiotics and deoxyribonucleic acid: equilibrium binding studies on interaction of daunomycin with deoxyribonucleic acid.

D. Crothers, J. Chaires, N. Dattagupta, 1982, Biochemistry.

Relaxation studies of the proflavine-DNA complex: the kinetics of an intercalation reaction.

H. J. Li, D. Crothers, H. Li, 1969, Journal of molecular biology.

The major adduct of the antitumor drug cis-diamminedichloroplatinum(II) with DNA bends the duplex by approximately equal to 40 degrees toward the major groove.

D. Crothers, S. Lippard, A. L. Pinto, 1988, Proceedings of the National Academy of Sciences of the United States of America.

The carbohydrate domain of calicheamicin gamma I1 determines its sequence specificity for DNA cleavage.

D. Crothers, J. Drak, S. Danishefsky, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Monte-Carlo simulation of multisite echinomycin-DNA interactions detected by in vitro transcription analysis.

D. Crothers, D. Phillips, R. White, 1990, Biochemistry.

Kinetics and sequence specificity of drug-DNA interactions: an in vitro transcription assay.

D. Crothers, D. Phillips, 1986, Biochemistry.

Kinetic and hydrodynamic studies of the complex of proflavine with poly A·poly U

D. Crothers, D. E. V. Schmechel, 1971, Biopolymers.

Relaxation kinetics of dimer formation by self complementary oligonucleotides.

D M Crothers, D. Crothers, P. Doty, 1971, Journal of molecular biology.

Fragments of the HIV-1 Tat protein specifically bind TAR RNA.

D M Crothers, D. Crothers, T. Steitz, 1990, Science.

Binding of daunomycin to calf thymus nucleosomes.

D. Crothers, J. Chaires, N. Dattagupta, 1983, Biochemistry.

Unfolding of nucleosomes by ethidium binding.

D. Crothers, N. Dattagupta, M. Hogan, 1980, Biochemistry.

Calculation of binding isotherms for heterogeneous polymers

D. Crothers, 1968, Biopolymers.

THE MELTING TRANSITION OF LOW-MOLECULAR-WEIGHT DNA: THEORY AND EXPERIMENT.

D. Crothers, B. Zimm, N. Kallenbach, 1965, Journal of molecular biology.

High‐resolution nmr studies of A‐ and G‐containing oligonucleotides

D. Crothers, B. W. Shum, 1983, Biopolymers.

Transient electric dichroism studies of the structure of the DNA complex with intercalated drugs.

D. Crothers, N. Dattagupta, M. Hogan, 1979, Biochemistry.

Self-association of daunomycin.

D. Crothers, J. Chaires, N. Dattagupta, 1982, Biochemistry.

Studies concerning the behavior of actinomycin in solution.

D. Crothers, S. Sabol, W. Müller, 1968, Biochemistry.

Statistical thermodynamics of nucleic acid melting transitions with coupled binding equilibria

D. Crothers, 1971, Biopolymers.

Orientation of nucleosomes in the thirty-nanometer chromatin fiber.

D. Crothers, N. Dattagupta, H. Yabuki, 1982, Biochemistry.

Viscosity and sedimentation of the DNA from bacteriophages T2 and T7 and the relation to molecular weight.

D. Crothers, B. Zimm, 1965, Journal of molecular biology.

Physical Chemistry: with Applications to the Life Sciences

Donald M. Crothers, D. Crothers, D. Eisenberg, 1979 .

A non-intercalating proflavine derivative.

D. Crothers, M. Waring, W. Müller, 1973, European journal of biochemistry.

Statistical-mechanical theory of DNA looping.

Yongli Zhang, D. Crothers, S. Levene, 2006, Biophysical journal.

Relaxation kinetics of DNA–ligand binding including direct transfer

D. Crothers, Dennis P. Ryan, 1984, Biopolymers.

DNA-ethidium reaction kinetics: demonstration of direct ligand transfer between DNA binding sites.

D. Crothers, J. L. Bresloff, Donald M. Crothers, 1975, Journal of molecular biology.

Stability and properties of double and triple helices: dramatic effects of RNA or DNA backbone composition.

D. Crothers, R. Roberts, 1992, Science.

On the kinetics of distamycin binding to its target sites on duplex DNA.

D M Crothers, D. Crothers, R Baliga, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Binding affinity and site selectivity of daunomycin analogues.

D. Crothers, S. Danishefsky, G. Sulikowski, 1994, Biochemistry.

Calculation of melting curves for DNA

D. Crothers, 1968, Biopolymers.

An ethidium-induced double helix of poly(dA)-poly(rU).

D. Crothers, E. A. Lehrman, 1977, Nucleic acids research.

Three-Dimensional Triple-Resonance 1H, 13C, 31P Experiment: Sequential Through-Bond Correlation of Ribose Protons and Intervening Phosphorus along the RNA Oligonucleotide Backbone

D. Crothers, H. Schwalbe, C. Anklin, 1994 .

Transient electric dichroism of rod-like DNA molecules.

D M Crothers, D. Crothers, N. Dattagupta, 1978, Proceedings of the National Academy of Sciences of the United States of America.

Specificity and stringency in DNA triplex formation.

D M Crothers, D. Crothers, R. Roberts, 1991, Proceedings of the National Academy of Sciences of the United States of America.

In vivo structural analysis of spliced leader RNAs in Trypanosoma brucei and Leptomonas collosoma: a flexible structure that is independent of cap4 methylations.

D. Crothers, E. Ullu, K. Harris, 1995, RNA.

The Leptomonas collosoma spliced leader RNA can switch between two alternate structural forms.

D M Crothers, D. Crothers, K A LeCuyer, 1993, Biochemistry.

NMR of enzymatically synthesized uniformly 13C15N-labeled DNA oligonucleotides.

D. Crothers, D. Zimmer, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Analysis of RNA secondary structure by photochemical reversal of psoralen crosslinks.

D. Crothers, D. Rabin, 1979, Nucleic acids research.

Studies of the complex between transfer RNAs with complementary anticodons. I. Origins of enhanced affinity between complementary triplets.

D. Crothers, D. Söll, H. Grosjean, 1976, Journal of molecular biology.

Kinetics of the stages of transcription initiation at the Escherichia coli lac UV5 promoter.

D. Crothers, S. B. Straney, 1987, Biochemistry.

Structural modifications of camptothecin and effects on topoisomerase I inhibition.

D. Crothers, R. Crow, 1992, Journal of medicinal chemistry.

Simplified methods for large scale enzymatic synthesis of oligoribonucleotides.

D. Crothers, B. W. Shum, 1978, Nucleic Acids Research.

Structural origins of adenine-tract bending

D. Crothers, Donald M Crothers, D. Zimmer, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Studies on interaction of anthracycline antibiotics and deoxyribonucleic acid: geometry of intercalation of iremycin and daunomycin.

H. Triebel, D. Crothers, J. Chaires, 1982, Biochemistry.

31P NMR studies of the solution structure and dynamics of nucleosomes and DNA.

D. Crothers, I. Armitage, L. Klevan, 1979, Nucleic acids research.

Major groove accessibility of RNA.

D. Crothers, K. Weeks, Donald M. Crothers, 1993, Science.

Specific chemical labeling of DNA fragments.

D. Crothers, D. Söll, H. Eshaghpour, 1979, Nucleic acids research.

Interaction of the aryl tetrasaccharide domain of calicheamicin .gamma.1I with DNA: influence on aglycon and methidiumpropyl-EDTA.cntdot.iron(II)-mediated DNA cleavage

D. Crothers, S. Danishefsky, J. Aiyar, 1992 .

RNase H cleavage for processing of in vitro transcribed RNA for NMR studies and RNA ligation.

D. Crothers, J. Lapham, Donald M. Crothers, 1996, RNA.

Bending and flexibility of kinetoplast DNA.

D. Crothers, S. Levene, H. M. Wu, 1986, Biochemistry.

A computer graphics study of sequence-directed bending in DNA.

D. Crothers, S. Levene, 1983, Journal of biomolecular structure & dynamics.

Rapid high-performance liquid chromatography of nucleic acids with polystyrene-based micropellicular anion exchangers.

D. Crothers, C. Horváth, Y. Maa, 1990, Journal of chromatography.

Preparative separation of the complementary strands of DNA restriction fragments by alkaline RPC-5 chromatography

Hubert Eshaghpour, Donald M. Crothers, D. Crothers, 1978, Nucleic Acids Res..

Kinetic discrimination in the folding of intramolecular triple helices.

D. Crothers, R. Roberts, 1996, Journal of molecular biology.

A PHAGE INFECTING SAPROSPIRA GRANDIS.

D. Crothers, R. Lewin, D. Correll, 1964, Canadian journal of microbiology.

Sequential correlation of anomeric ribose protons and intervening phosphorus in RNA oligonucleotides by a 1H,13C,31P triple resonance experiment: HCP-CCH-TOCSY

D. Crothers, H. Schwalbe, C. Anklin, 1995, Journal of biomolecular NMR.

On the physical basis for ambiguity in genetic coding interactions.

D. Crothers, H. Grosjean, S. Henau, 1978, Proceedings of the National Academy of Sciences of the United States of America.

Condensation of chromatin: role of multivalent cations.

D. Crothers, D. Sen, 1986, Biochemistry.

Equilibrium studies of the cyclic AMP receptor protein-DNA interaction.

D. Crothers, M. Fried, 1984, Journal of molecular biology.

Kinetics of an RNA conformational switch.

D M Crothers, D. Crothers, K A LeCuyer, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Characterization of covalent adriamycin-DNA adducts.

D. Crothers, D. Phillips, S. Zeman, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Statistical mechanics of sequence-dependent circular DNA and its application for DNA cyclization.

D. Crothers, Yongli Zhang, 2003, Biophysical journal.

Bending and flexibility of methylated and unmethylated EcoRI DNA.

D. Crothers, Dafna Nathan, Donald M Crothers, 2002, Journal of molecular biology.

Kinetics and mechanism in the reaction of gene regulatory proteins with DNA.

M G Fried, D M Crothers, D. Crothers, 1984, Journal of molecular biology.

The influence of polyvalency on the binding properties of antibodies.

D M Crothers, D. Crothers, H. Metzger, 1972, Immunochemistry.

RNA recognition by Tat-derived peptides: Interaction in the major groove?

D. Crothers, K. Weeks, 1991, Cell.

High-throughput approach for detection of DNA bending and flexibility based on cyclization

Donald M. Crothers, Yongli Zhang, D. Crothers, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Interaction of human immunodeficiency virus type 1 Tat-derived peptides with TAR RNA.

D. Crothers, K. Long, 1995, Biochemistry.

RNA targeting by the HIV-1 Tat protein

D. Crothers, K. Weeks, 1993 .

Physical studies of nucleosome assemble.

D. Crothers, N. Dattagupta, M. Hogan, 1978, Biochemistry.

Isolation and characterization of a spacerless dinucleosome from Hl-depleted chromatin

D. Crothers, L. Klevan, 1977 .

Localization of the structural change induced in tRNA fMET (Escherichia coli) by acidic pH.

D. Crothers, M. Bina-Stein, 1975, Biochemistry.

Inhibition of topoisomerase I by anthracycline antibiotics: evidence for general inhibition of topoisomerase I by DNA-binding agents.

D. Crothers, R. Crow, 1994, Journal of medicinal chemistry.

Site selectivity of daunomycin.

D. Crothers, J. Thomson, Camille J. Roche, 1994, Biochemistry.

The 3' terminus of 16S rRNA: secondary structure and interaction with ribosomal protein S1.

J. Steitz, D. Crothers, R. Yuan, 1979, Nucleic acids research.

Fos and Jun do not bend the AP-1 recognition site.

D. Crothers, A. Sitlani, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Equilibrium binding of magnesium(II) by Escherichia coli tRNAfMet.

D M Crothers, D. Crothers, A. Stein, 1976, Biochemistry.

Artificial nucleosome positioning sequences.

D M Crothers, D. Crothers, T E Shrader, 1989, Proceedings of the National Academy of Sciences of the United States of America.

Calculation of binding isotherms for heterogenous polymers.

D. Crothers, 1968, Biopolymers.

DNA bending in protein-DNA complexes.

D M Crothers, D. Crothers, M. Gartenberg, 1991, Methods in enzymology.

Lac repressor is a transient gene-activating protein

Donald M. Crothers, D. Crothers, Susan B. Straney, 1987, Cell.

Identification and characterization of genomic nucleosome-positioning sequences.

D M Crothers, D. Crothers, J. Kahn, 1997, Journal of molecular biology.

The homeo domain of a murine protein binds 5' to its own homeo box.

D. Crothers, F. Ruddle, A. Fainsod, 1986, Proceedings of the National Academy of Sciences of the United States of America.

Stepwise binding and bending of DNA by Escherichia coli integration host factor

D. Crothers, Sawako Sugimura, 2006, Proceedings of the National Academy of Sciences.

Analysis of In-Vivo LacR-Mediated Gene Repression Based on the Mechanics of DNA Looping

Donald M. Crothers, Yongli Zhang, Stephen D. Levene, 2006, PloS one.

Sequence elements responsible for DNA curvature.

D M Crothers, D. Crothers, J. Kahn, 1994, Journal of molecular biology.

THEORY OF THE MELTING TRANSITION OF SYNTHETIC POLYNUCLEOTIDES: EVALUATION OF THE STACKING FREE ENERGY.

D. Crothers, B. Zimm, D M CROTHERS, 1964, Journal of molecular biology.

Measurement of the DNA bend angle induced by the catabolite activator protein using Monte Carlo simulation of cyclization kinetics.

D. Crothers, J. Kahn, 1998, Journal of molecular biology.

Synergy between Escherichia coli CAP protein and RNA polymerase in the lac promoter open complex.

D M Crothers, D. Crothers, D. Straney, 1989, Journal of molecular biology.

The DNA binding domain and bending angle of E. coli CAP protein

D. Crothers, M. Gartenberg, Huei-Nin Liu-Johnson, 1986, Cell.

Protein-induced bending and DNA cyclization.

D M Crothers, D. Crothers, J. Kahn, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Interaction of netropsin and distamycin with deoxyribonucleic acid: electric dichroism study.

D. Crothers, N. Dattagupta, M. Hogan, 1980, Biochemistry.

Intermediates in transcription initiation and propagation.

D. Crothers, D. Straney, 1986, Biochemical Society transactions.

Global structure and mechanical properties of a 10-bp nucleosome positioning motif.

D. Crothers, J. Lapham, A. Sitlani, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Characterization of the ATF/CREB site and its complex with GCN4.

D. Crothers, J. Kahn, S. C. Hockings, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Determination of the extent of DNA bending by an adenine-thymine tract.

D. Crothers, J. Drak, H. Koo, 1990, Biochemistry.

Comparison of several calculations of helix–coil transitions in hetergeneous polymers

D. Crothers, T. R. Fink, 1968, Biopolymers.

Effect of drug-DNA interactions upon transcription initiation at the lac promoter.

D. Crothers, D. Straney, 1987, Biochemistry.

Kinetic consequences of covalent linkage of DNA binding polyamides.

D M Crothers, D. Crothers, P. Dervan, 2001, Biochemistry.

Conformational changes of transfer RNA. The role of magnesium(II).

D. Crothers, A. Stein, Crothers Dm, 1976, Biochemistry.

Theory of the influence of oligonucleotide chain conformation on double helix stability

C. DeLisi, D. Crothers, 1971 .

Mechanism of deoxyribonucleic acid unwinding

D. Crothers, 1969 .

Influence of ionic strength on the dichroism properties of polynucleosomal fibers

D. Crothers, Keun Su Lee, Donald M. Crothers, 1982, Biopolymers.

Architectural elements in nucleoprotein complexes

D. Crothers, 1993, Current Biology.

The contribution of proximity and orientation to catalytic reaction rates

C. DeLisi, D. Crothers, 1973 .

Conformation of a bulge‐containing oligomer from a hot‐spot sequence by NMR and energy minimization

D. Crothers, S. Woodson, 1989, Biopolymers.

DNA bending by the bulge defect.

D. Crothers, J. A. Rice, J. Rice, 1989, Biochemistry.

Structural model for an oligonucleotide containing a bulged guanosine by NMR and energy minimization.

D. Crothers, S. Woodson, 1988, Biochemistry.

Proton nuclear magnetic resonance studies on bulge-containing DNA oligonucleotides from a mutational hot-spot sequence.

D M Crothers, D. Crothers, S. Woodson, 1987, Biochemistry.

CAP binding to B and Z forms of DNA.

D. Crothers, M. Fried, H. M. Wu, 1983, Nucleic acids research.

Concerted binding and bending of DNA by Escherichia coli integration host factor.

D. Crothers, M. Chance, M. Brenowitz, 2002, Journal of molecular biology.

Binding kinetics of mercury(II) TO POLYRIBONUCLEOTIDES.

M. N. Williams, D. Crothers, 1975, Biochemistry.

Detection of localized DNA flexibility

D. Crothers, J. Kahn, Elizabeth Yun, 1994, Nature.

Nucleic Acid Hybridization: A Rapid Method for the Diagnosis of Infectious Diseases

D. Crothers, N. Dattagupta, P. Rae, 1989 .

Thermodynamic studies of a model system for hydrophobic bonding.

D. Crothers, D. I. Ratner, 1968, Biochemistry.

The role of nucleotide cofactor binding in cooperativity and specificity of MutS recognition.

D. Crothers, Shar-yin N. Huang, 2008, Journal of molecular biology.

Novel insights on the DNA interaction of calicheamicin γ1I

D. Crothers, S. Moro, C. Sissi, 2015, Biopolymers.

DNA curvature and deformation in protein-DNA complexes: a step in the right direction.

D M Crothers, D. Crothers, 1998, Proceedings of the National Academy of Sciences of the United States of America.

On the Helix—Coil Transition in Heterogeneous Polymers

D. Crothers, N. Kallenbach, 1966 .

On the DNA Recognition Role of the Carbohydrate Sector in Calicheamicin: A Comparison of DNA Cleaving Capacity of Enantiomeric Calicheamicinones

D. Crothers, S. Hitchcock, K. Liu, 1994 .

Conformational changes of transfer ribonucleic acid. Comparison of the early melting transition of two tyrosine-specific transfer ribonucleic acids.

D. Crothers, S. K. Yang, 1972, Biochemistry.

Theory of friction‐limited DNA unwinding

Hanns-Christof Spatz, Donald M. Crothers, D. Crothers, 1971 .

Direct physical evidence for secondary structure in an isolated fragment of R17 bacteriophage mRNA

J. Steitz, D. Crothers, J. Gralla, 1974, Nature.

Comparison of the open complexes formed by RNA polymerase at the Escherichia coli lac UV5 promoter.

D. Crothers, D. Straney, 1987, Journal of molecular biology.

An in vitro transcription assay for probing drug-DNA interactions during active transcription of DNA.

D. Crothers, D. Phillips, 1995, Methods in molecular biology.

Catabolite activator protein-induced DNA bending in transcription initiation.

D. Crothers, S. Zinkel, 1991, Journal of molecular biology.

Gel electrophoresis of protein–DNA complexes

D. Crothers, 1987, Nature.

Direct observation of DNA bending/unbending kinetics in complex with DNA-bending protein IHF

Donald M. Crothers, D. Crothers, A. Ansari, 2006, Proceedings of the National Academy of Sciences.

Topological distributions and the torsional rigidity of DNA. A Monte Carlo study of DNA circles.

D. Crothers, S. Levene, 1986, Journal of molecular biology.

Binding of 9-aminoacridine to bulged-base DNA oligomers from a frame-shift hot spot.

D. Crothers, S. Woodson, 1988, Biochemistry.

Modulation of mitomycin cross-linking by DNA bending in the Escherichia coli CAP protein-DNA complex.

D. Crothers, C. Cera, 1989, Biochemistry.

Structural basis for DNA bending.

D. Crothers, J. G. Nadeau, 1989, Proceedings of the National Academy of Sciences of the United States of America.

Site-specific cleavage of transcript RNA.

D. Crothers, J. Lapham, 2000, Methods in enzymology.

Measurement of diffusion constants for nucleic acids by NMR

D. Crothers, P. Moore, J. P. Rife, 1997, Journal of biomolecular NMR.

Sequence-dependent contribution of distal binding domains to CAP protein-DNA binding affinity.

D. Crothers, M. Gartenberg, D. Dalma‐Weiszhausz, 1991, Nucleic acids research.

Physical characterization of a ribosomal nucleoprotein complex.

D. Crothers, T. Tritton, 1976, Biochemistry.

Conformational changes of transfer ribonucleic acid. Equilibrium phase diagrams.

D. Crothers, P. E. Cole, S. K. Yang, 1972, Biochemistry.

New insight into drug-DNA interactions at individual drug binding sites probed by RNA polymerase during active transcription of the DNA.

D. Crothers, C. Cullinane, D. Phillips, 1990, Anti-cancer drug design.

Kinetic studies of drug-dinucleotide complexes.

D. Crothers, P. Davanloo, 1976, Biochemistry.

Phase partition studies of actinomycin-nucleotide complexes.

D. Crothers, P. Davanloo, 1976, Biochemistry.

4 – RNA Conformational Dynamics

D. Crothers, 2001 .

Interaction of calicheamicin γ1I and its related carbohydrates with DNA–protein complexes

D. Crothers, S. Danishefsky, C. Sissi, 1999 .

RNA Folding Pathways

D. Crothers, 2000, Current protocols in nucleic acid chemistry.

Cooperativity in A-tract structure and bending properties of composite TnAn blocks.

D. Crothers, T. Haran, 1989, Biochemistry.

High‐resolution NMR of exchangeable protons in arginine, oligoarginines, and the arginine‐rich histone tetramer

D. Crothers, Leonard Klavan, 1979 .

Determinants of RNA hairpin loop-loop complex stability.

D. Crothers, R. Gregorian, Donald M. Crothers, 1995, Journal of molecular biology.

Global features of DNA structure by comparative gel electrophoresis.

D M Crothers, D. Crothers, J. Drak, 1992, Methods in enzymology.

Synthetic DNA bending sequences increase the rate of in vitro transcription initiation at the Escherichia coli lac promoter.

D. Crothers, M. Gartenberg, 1991, Journal of molecular biology.

Anomalous DNA binding by E2 regulatory protein driven by spacer sequence TATA

D. Crothers, Z. Shakked, R. Hegde, 2010, Nucleic acids research.

Fine Tuning Gene Regulation

D. Crothers, 2013, Science.

Correlation of adenine H2/H8 resonances in uniformly 13C labeled RNAs by 2D HCCH-TOCSY : a new tool for 1H assignment

D. Crothers, J. Prestegard, J. Marino, 1994 .

Synthesis and a Preliminary DNA Binding Study of Hybrids of the Carbohydrate Domain of Calicheamicin γ 1I and the Aglycone of Daunorubicin: Calichearubicins A and B

D. Crothers, S. Danishefsky, K. Depew, 1996 .

Modulation of the stability of a gene-regulatory protein dimer by DNA and cAMP.

D. Crothers, A. Brown, 1989, Proceedings of the National Academy of Sciences of the United States of America.

Characterization of the solution conformations of unbound and Tat peptide-bound forms of HIV-1 TAR RNA.

D. Crothers, K. Long, 1999, Biochemistry.

Nuclear magnetic resonance study of hydrogen-bonded ring protons in Watson-Crick base pairs.

D. Crothers, C. W. Hilbers, R. Shulman, 1973, Proceedings of the National Academy of Sciences of the United States of America.

CAP and RNA polymerase interactions with the lac promoter: binding stoichiometry and long range effects

M G Fried, D M Crothers, D. Crothers, 1983, Nucleic Acids Res..

Cooperativity in A-tract structure and the bending properties of composite TnAn blocks [Erratum to document cited in CA110(17):149972R]

D. Crothers, T. Haran, 1989 .

The preparation, preservation, and properties of high molecular weight polyadenylic acid.

D. Crothers, D. Hennage, D. Ludlum, 1969, Biochemistry.

On the form of the partition function for the helix–coil transition of random copolymers

D. Crothers, 1966 .

Calculation of kinetic curves for the helix–coil transition of polypeptides

D. Crothers, M. E. Craig, 1968, Biopolymers.

Preferential location of bulged guanosine internal to a G.C tract by 1H NMR.

D. Crothers, S. Woodson, 1988, Biochemistry.

Conformational changes of transfer ribonucleic acid. Relaxation kinetics of the early melting transition of methionine transfer ribonucleic acid (Escherichia coli).

D. Crothers, P. E. Cole, 1972, Biochemistry.

Physical Studies of tRNA in Solution

D. Crothers, 1979 .

Nucleic acid aggregation geometry and the possible evolutionary origin of ribosomes and the genetic code.

D. Crothers, 1982, Journal of molecular biology.

Characterization of the ATF y CREB site and its complex with GCN 4

D. Crothers, J. Kahn, S. C. Hockings, 1998 .

In memory of Julian Munson Sturtevant.

D. Crothers, 2007, Biophysical chemistry.

Local effects of partial adenine‐N1‐oxidation on poly A · poly U and poly A · 2 poly U helix conformations

D. Crothers, T. R. Fink, 1972, Biopolymers.

DNA Bending and Protein-DNA Interactions

D. Crothers, S. Levene, Hen-Ming Wu, 1983 .

Computation of molecular weight averages for DNA molecules containing both preformed and randomly induced single‐strand breaks

D. Crothers, E. Elson, H. Spatz, 1969, Biopolymers.

Interpretation of the kinetics of helix formation.

D. Crothers, N. Kallenbach, R. Mortimer, 1963, Biochemical and biophysical research communications.

Selective repression of transcription by base sequence specific synthetic polymers.

D. Crothers, N. Dattagupta, L. D. Kosturko, 1979, Biochemistry.