H. Heng

发表

The murine Xe169 gene escapes X–inactivation like its human homologue

Jingshi Wu, E. Salido, P. Yen, 1994, Nature Genetics.

SEX REDUCES GENETIC VARIATION: A MULTIDISCIPLINARY REVIEW

H. Heng, R. Gorelick, 2011, Evolution; international journal of organic evolution.

Male mouse meiotic chromosome cores deficient in structural proteins SYCP3 and SYCP2 align by homology but fail to synapse and have possible impaired specificity of chromatin loop attachment

H. Heng, N. Kolas, C. Hoog, 2004, Cytogenetic and Genome Research.

Health and Disease—Emergent States Resulting From Adaptive Social and Biological Network Interactions

H. Heng, R. Melis, M. O. Olde Rikkert, 2019, Front. Med..

S. Scherer, H. Heng, L. Tsui, 1997, Genomics.

Abstracts from the 3rd Conference on Aneuploidy and Cancer: Clinical and Experimental Aspects

O. A. Kovaleva, Batoul Y. Abdallah, A. Cornish-Bowden, 2017, Molecular Cytogenetics.

Malignant fibrous histiocytoma two years after autologous stem cell transplant for Hodgkin lymphoma: Evidence for genomic instability

H. Heng, R. Rabah, A. Konski, 2011, Pediatric blood & cancer.

The human β-defensin-1 and α-defensins are encoded by adjacent genes : Two peptide families with differing disulfide topology share a common ancestry

H. Heng, T. Ganz, Lide Liu, 1997 .

Chromosomal instability (CIN): what it is and why it is crucial to cancer evolution

Henry H. Heng, Steven D. Horne, Guo Liu, 2013, Cancer and Metastasis Reviews.

Identification of Sonic hedgehog as a candidate gene responsible for holoprosencephaly

C. Helms, E. Belloni, E. Roessler, 1996, Nature Genetics.

DNA vaccination controls Her-2+ tumors that are refractory to targeted therapies.

H. Heng, M. Piechocki, Wei-Zen Wei, 2008, Cancer research.

Heterogeneous duplications in patients with Pelizaeus-Merzbacher disease suggest a mechanism of coupled homologous and nonhomologous recombination.

N. Carter, H. Heng, M. Ross, 2005, American journal of human genetics.

Simulation of Karyotype Evolution and Biodiversity in Asexual and Sexual Reproduction

Batoul Y. Abdallah, H. Heng, Hui Jiang, 2018, bioRxiv.

Detecting Chromosome Condensation Defects in Gulf War Illness Patients

Batoul Y. Abdallah, H. Heng, S. Horne, 2017, Current genomics.

Transient and stable vector transfection: Pitfalls, off-target effects, artifacts.

H. Heng, A. Stepanenko, 2017, Mutation research.

FISH detection on DAPI-banded chromosomes.

H. Heng, L. Tsui, 1994, Methods in molecular biology.

Comparison of mitotic cell death by chromosome fragmentation to premature chromosome condensation

Sarah M. Regan, Batoul Y. Abdallah, H. Heng, 2010, Molecular Cytogenetics.

Reductionism The Conflict Between Complex Systems and

H. Heng, 2008 .

Questions to guide cancer evolution as a framework for furthering progress in cancer research and sustainable patient outcomes

H. Heng, M. Gerlinger, A. Marusyk, 2022, Medical Oncology.

Physical mapping of receptor type protein tyrosine phosphatase sigma (PTPRS) to human chromosome 19p13.3.

H. Heng, A. Olsen, L. Gordon, 1996, Genomics.

Discovery of three novel G-protein-coupled receptor genes.

H. Heng, L. F. Kolakowski, B. O'dowd, 1998, Genomics.

Transcriptional signatures of unfolded protein response implicate the limitation of animal models in pathophysiological studies

H. Heng, Ze Zheng, Kezhong Zhang, 2016, Environmental disease.

Genomic organization and FISH mapping of human Pmel 17, the putative silver locus.

H. Heng, L. Tsui, B. Kwon, 1996, Pigment cell research.

SV40 T antigen interacts with Nbs1 to disrupt DNA replication control.

H. Heng, D. Livingston, T. Chiba, 2004, Genes & development.

Identification of the mouse β`-COP golgi component as a spermatocyte autoantigen in scleroderma and mapping of its gene Copb2 to mouse Chromosome 9

H. Heng, R. Pearlman, P. Moens, 1999, Cytogenetic and Genome Research.

Regulation of meiotic chromatin loop size by chromosomal position.

H. Heng, L. Tsui, P. Moens, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Cloning, expression, and chromosomal localization to 11p12-13 of a human LIM/HOMEOBOX gene, hLim-1.

H. Heng, L. Tsui, M. Minden, 1997, DNA and cell biology.

Challenges and new strategies for Gulf War illness research

H. Heng, 2016 .

Free chromatin mapping by FISH.

H. Heng, L. Tsui, 1994, Methods in molecular biology.

High-resolution mapping of mammalian genes by in situ hybridization to free chromatin.

H. Heng, L. Tsui, J. Squire, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Cloning of a DSS1 pseudogene (DSS1P1) and mapping to human Chromosome band 5ql4

S. Scherer, H. Heng, L. Tsui, 1997, Mammalian Genome.

Chromosomal mapping of the second humanCD8B gene locus

H. Heng, L. Tsui, J. Parnes, 2004, Immunogenetics.

Complexity of CNC Transcription Factors As Revealed by Gene Targeting of the Nrf3 Locus

H. Heng, N. Andrews, R. Ahmed, 2004, Molecular and Cellular Biology.

Modes of DAPI banding and simultaneous in situ hybridization

H. Heng, L. Tsui, 1993, Chromosoma.

Organization of heterologous DNA inserts on the mouse meiotic chromosome core

H. Heng, L. Tsui, P. Moens, 1994, Chromosoma.

Alternative promoters and polyadenylation regulate tissue‐specific expression of Hemogen isoforms during hematopoiesis and spermatogenesis

H. Heng, A. Gow, Li Li, 2003, Developmental dynamics : an official publication of the American Association of Anatomists.

Down-regulation of a novel actin-binding molecule, skeletrophin, in malignant melanoma.

H. Heng, Y. Ohtsuki, H. Sonobe, 2003, The American journal of pathology.

DNA-protein in situ covisualization for chromosome analysis.

H. Heng, P. Moens, B. Spyropoulos, 2000, Methods in molecular biology.

Overlapping and non-overlapping Ptch2 expression with Shh during mouse embryogenesis

H. Heng, L. Tsui, M. Crackower, 1998, Mechanisms of Development.

Chromosomal mapping and expression of the human B120 gene.

H. Heng, M. Furihata, Y. Ohtsuki, 1998, Gene.

Genomic organization and functional analysis of the murine protein phosphatase 1c gamma (Ppp1cc) gene.

H. Heng, M. Tyers, S. Trevisanato, 1997, Genomics.

Assignment of the human dUTPase gene (DUT) to chromosome 15q15-q21. 1 by fluorescence in situ hybridization.

H. Heng, L. Tsui, R. Pearlman, 1997, Genomics.

Localization of three novel zinc finger genes to the centromeric region of human chromosome 10 by fluorescencein situ hybridization

H. Heng, C. Liew, E. Cukerman, 1996, Somatic cell and molecular genetics.

Cloning, Expression, and Chromosomal Localization of the Human Uridine Nucleotide Receptor Gene (*)

J. T. Turner, H. Heng, B. O'dowd, 1995, The Journal of Biological Chemistry.

Cloning genes encoding receptors related to chemoattractant receptors.

H. Heng, L. F. Kolakowski, B. O'dowd, 1998, Genomics.

A novel human gene encoding a G-protein-coupled receptor (GPR15) is located on chromosome 3.

H. Heng, B. O'dowd, S. George, 1996, Genomics.

Mapping of a human LIM protein (CLP) to human chromosome 11p15.1 by fluorescence in situ hybridization.

H. Heng, C. Liew, Y. W. Fung, 1995, Genomics.

Mitotic cell death by chromosome fragmentation.

H. Heng, S. Krawetz, Yi Sun, 2007, Cancer research.

Cloning of human genes encoding novel G protein-coupled receptors.

H. Heng, L. Tsui, B. O'dowd, 1994, Genomics.

ER Stress and Micronuclei Cluster: Stress Response Contributes to Genome Chaos in Cancer

H. Heng, Kezhong Zhang, Guo Liu, 2021, Frontiers in Cell and Developmental Biology.

The Genes for the α and β Subunits of the Mitochondrial Trifunctional Protein Are Both Located in the Same Region of Human Chromosome 2p23

H. Heng, C. Roe, Bing-zhi Yang, 1996 .

Discovery of a novel human G protein-coupled receptor gene (GPR25) located on chromosome 1.

H. Heng, L. F. Kolakowski, B. O'dowd, 1997, Biochemical and biophysical research communications.

Identical megabase transgenes on mouse chromosomes 3 and 4 do not promote ectopic pairing or synapsis at meiosis.

H. Heng, J. Heddle, P. Moens, 1997, Genome.

Genes encoding general initiation factors for RNA polymerase II transcription are dispersed in the human genome.

H. Heng, L. Tsui, J. Greenblatt, 1994, Human molecular genetics.

Preface

H. Heng, 2013, Cytogenetic and Genome Research.

Editorial: Somatic genomic mosaicism & human disease

H. Heng, I. Iourov, 2022, Frontiers in genetics.

MLK-3: identification of a widely-expressed protein kinase bearing an SH3 domain and a leucine zipper-basic region domain.

H. Heng, L. Tsui, N. Lassam, 1994, Oncogene.

Questions to guide cancer evolution as a framework for furthering progress in cancer research and sustainable patient outcomes

H. Heng, M. Gerlinger, A. Marusyk, 2022, Medical Oncology.

Regional localization of 725 human chromosome 7-specific yeast artificial chromosome clones.

S. Scherer, H. Heng, L. Tsui, 1994, Genomics.

Localization of the human gene for inducible nitric oxide synthase (NOS2) to chromosome 17q11.2-q12.

H. Heng, L. Tsui, P. Marsden, 1994, Genomics.

The cloning and chromosomal mapping of two novel human opioid-somatostatin-like receptor genes, GPR7 and GPR8, expressed in discrete areas of the brain.

H. Heng, L. Tsui, B. O'dowd, 1995, Genomics.

Nuclear matrix association: switching to the invasive cytotrophoblast.

H. Heng, S. Krawetz, A. Platts, 2010, Placenta.

Fluorescence in situ hybridization mapping of the cystic fibrosis transmembrane conductance regulator (CFTR) gene to 7q31.3.

H. Heng, L. Tsui, X. Shi, 1993, Cytogenetics and cell genetics.

Chromosomal instability (CIN): what it is and why it is crucial to cancer evolution

H. Heng, S. Horne, B. Abdallah, 2013, Cancer and Metastasis Reviews.

The genome‐centric concept: resynthesis of evolutionary theory

H. Heng, 2009, BioEssays : news and reviews in molecular, cellular and developmental biology.

Genome chaos: Creating new genomic information essential for cancer macroevolution.

H. Heng, Julie Heng, 2020, Seminars in cancer biology.

From DNA structure to gene expression: mediators of nuclear compartmentalization and dynamics

H. Heng, S. Krawetz, C. Benham, 2004, Chromosome Research.

A Postgenomic Perspective on Molecular Cytogenetics

Henry H. Heng, Steven D. Horne, Sophia Chaudhry, 2017, Current genomics.

Why it is crucial to analyze non clonal chromosome aberrations or NCCAs?

Sarah M. Regan, H. Heng, Guo Liu, 2016, Molecular Cytogenetics.

Identification and cloning of three novel human G protein-coupled receptor genes GPR52, PsiGPR53 and GPR55: GPR55 is extensively expressed in human brain.

H. Heng, B. O'dowd, S. George, 1999, Brain research. Molecular brain research.

ATM and p21 cooperate to suppress aneuploidy and subsequent tumor development.

H. Heng, C. Deng, Yaolin Wang, 2005, Cancer research.

Re-defining the chromatin loop domain

H. Heng, S. Krawetz, S. Bremer, 2001, Cytogenetic and Genome Research.

FISH technology in chromosome and genome research.

H. Heng, P. Moens, B. Spyropoulos, 1997, BioEssays : news and reviews in molecular, cellular and developmental biology.

Somatic Genomic Mosaicism in Multiple Myeloma

H. Heng, Guo Liu, C. Ye, 2020, Frontiers in Genetics.

Imaging genome abnormalities in cancer research

H. Heng, Guo Liu, S. Bremer, 2004, Cell & chromosome.

Challenges and Opportunities for Clinical Cytogenetics in the 21st Century

H. Heng, Eric Heng, Sanjana Thanedar, 2023, Genes.

Unclassified Chromosome Abnormalities and Genome Behavior in Interphase

Sarah M. Regan, Batoul Y. Abdallah, H. Heng, 2020 .

Understanding aneuploidy in cancer through the lens of system inheritance, fuzzy inheritance and emergence of new genome systems

Sarah M. Regan, H. Heng, Guo Liu, 2018, Molecular Cytogenetics.

Karyotype Heterogeneity and Unclassified Chromosomal Abnormalities

Batoul Y. Abdallah, H. Heng, S. Horne, 2013, Cytogenetic and Genome Research.

Genetic and Epigenetic Heterogeneity in Cancer

H. Heng, S. Horne, B. Abdallah, 2011 .

Evolutionary mechanisms and diversity in cancer.

Batoul Y. Abdallah, H. Heng, B. Abdallah, 2011, Advances in cancer research.

Genetic and epigenetic heterogeneity in cancer: A genome‐centric perspective

H. Heng, Guo Liu, S. Bremer, 2009, Journal of cellular physiology.

Genome based cell population heterogeneity promotes tumorigenicity: The evolutionary mechanism of cancer

H. Heng, A. Jaiswal, S. Narayan, 2009, Journal of cellular physiology.

Patterns of Genome Dynamics and Cancer Evolution

H. Heng, Guo Liu, S. Bremer, 2008, Cellular oncology : the official journal of the International Society for Cellular Oncology.

The dynamics of cancer chromosomes and genomes

H. Heng, S. Bremer, C. Ye, 2007, Cytogenetic and Genome Research.

Cancer progression by non‐clonal chromosome aberrations

Joshua Stevens, Fred Miller, H. Heng, 2006, Journal of cellular biochemistry.

Stochastic cancer progression driven by non‐clonal chromosome aberrations

H. Heng, M. Tainsky, Gen Sheng Wu, 2006, Journal of cellular physiology.

Clonal and non-clonal chromosome aberrations and genome variation and aberration.

H. Heng, Guo Liu, S. Bremer, 2006, Genome.

Gene Mapping by Fluorescence In Situ Hybridization

H. Heng, B. Beatty, 2006 .

Combined multicolor-FISH and immunostaining

H. Heng, S. Bremer, J. Stevens, 2006, Cytogenetic and Genome Research.

The hyaluronidase gene HYAL1 maps to chromosome 3p21.2-p21.3 in human and 9F1-F2 in mouse, a conserved candidate tumor suppressor locus.

S. Scherer, H. Heng, A. Csoka, 1998, Genomics.

Stress, genomic adaptation, and the evolutionary trade-off

H. Heng, S. Horne, S. Chowdhury, 2014, Front. Genet..

Genomic instability and histone H3 phosphorylation induction by the Ras‐mitogen activated protein kinase pathway in pancreatic cancer cells

H. Heng, J. Davie, James R Davie, 2009, International journal of cancer.

Chromatin loops are selectively anchored using scaffold/matrix-attachment regions

Sandra Goetze, Stephen A Krawetz, Guo Liu, 2004, Journal of Cell Science.

Structure and mapping of the human beta-defensin HBD-2 gene and its expression at sites of inflammation.

H. Heng, T. Ganz, C. Zhao, 1998, Gene.

A novel gene codes for a putative G protein‐coupled receptor with an abundant expression in brain

H. Heng, L. F. Kolakowski, B. O'dowd, 1996, FEBS letters.

Understanding aneuploidy in cancer through the lens of system inheritance, fuzzy inheritance and emergence of new genome systems

Sarah M. Regan, H. Heng, Guo Liu, 2018, Molecular Cytogenetics.

Two-phased evolution: Genome chaos-mediated information creation and maintenance.

H. Heng, Julie Heng, 2021, Progress in biophysics and molecular biology.

Ovarian cancer evolution through stochastic genome alterations: defining the genomic role in ovarian cancer

Batoul Y. Abdallah, H. Heng, M. Kurkinen, 2014, Systems biology in reproductive medicine.

Single cell heterogeneity

H. Heng, S. Krawetz, B. Vanderhyden, 2013, Cell cycle.

Cancer genome sequencing: the challenges ahead.

H. Heng, 2007, BioEssays : news and reviews in molecular, cellular and developmental biology.

Amplification of CFTR exon 9 sequences to multiple locations in the human genome.

H. Heng, L. Tsui, J. Rommens, 1997, Genomics.

A human gene that shows identity with the gene encoding the angiotensin receptor is located on chromosome 11.

H. Heng, L. Tsui, J. Kennedy, 1993, Gene.

HDAC4, a Human Histone Deacetylase Related to Yeast HDA1, Is a Transcriptional Corepressor

H. Heng, Jiahuai Han, N. Bertos, 1999, Molecular and Cellular Biology.

Genome Chaos, Information Creation, and Cancer Emergence: Searching for New Frameworks on the 50th Anniversary of the “War on Cancer”

H. Heng, Julie Heng, 2021, Genes.

Origins and Consequences of Chromosomal Instability: From Cellular Adaptation to Genome Chaos-Mediated System Survival

H. Heng, C. Ye, Zachary J. Sharpe, 2020, Genes.

Heng Reductionism The Conflict Between Complex Systems and Correction

H. Heng, Henry H Q Heng, 2008 .

Pharmacological ER stress promotes hepatic lipogenesis and lipid droplet formation.

H. Heng, Kezhong Zhang, Roberto Mendez, 2012, American journal of translational research.

Why imatinib remains an exception of cancer research

Batoul Y. Abdallah, H. Heng, S. Horne, 2013, Journal of cellular physiology.

Karyotype coding: The creation and maintenance of system information for complexity and biodiversity

Henry H. Heng, Julie Heng, H. Heng, 2021, Biosyst..

Therapy Induced Genome Chaos: A Novel Mechanism of Rapid Cancer Drug Resistance

H. Heng, S. Horne, J. Ye, 2021, Frontiers in Cell and Developmental Biology.

What Is Karyotype Coding and Why Is Genomic Topology Important for Cancer and Evolution?

H. Heng, Guo Liu, C. Ye, 2019, Front. Genet..

Micronuclei and Genome Chaos: Changing the System Inheritance

Sarah M. Regan, Batoul Y. Abdallah, H. Heng, 2019, Genes.

Genotype, environment, and evolutionary mechanism of diseases

Sarah M. Regan, H. Heng, C. Ye, 2016 .

Genome chaos: Survival strategy during crisis

Batoul Y. Abdallah, David J. Chen, H. Heng, 2014, Cell cycle.

Genome constraint through sexual reproduction: application of 4D-Genomics in reproductive biology

Batoul Y. Abdallah, H. Heng, S. Horne, 2013, Systems biology in reproductive medicine.

Decoding the genome beyond sequencing: the new phase of genomic research.

Guo Liu, Batoul Y. Abdallah, H. Heng, 2011, Genomics.

Diverse system stresses: common mechanisms of chromosome fragmentation

Batoul Y. Abdallah, H. Heng, S. Krawetz, 2011, Cell Death and Disease.

Elimination of altered karyotypes by sexual reproduction preserves species identity.

H. Heng, 2007, Genome.

Identification of genes from a 500-kb region at 7q11.23 that is commonly deleted in Williams syndrome patients.

S. Scherer, H. Heng, L. Tsui, 1996, Genomics.

Differentiating Chromosome Fragmentation and Premature Chromosome Condensation

H. Heng, J. Stevens, 2013 .

Experimental Induction of Genome Chaos.

H. Heng, Guo Liu, C. Ye, 2018, Methods in molecular biology.

Chromosomal instability and transcriptome dynamics in cancer

Henry H. Heng, Steven D. Horne, Batoul Y. Abdallah, 2013, Cancer and Metastasis Reviews.

Chromosome cores and chromatin at meiotic prophase.

H. Heng, R. Pearlman, P. Moens, 1998, Current topics in developmental biology.

7 Chromosome Cores and Chromatin at Meiotic Prophase

H. Heng, R. Pearlman, P. Moens, 1997 .

Emerging Role of Chimeric RNAs in Cell Plasticity and Adaptive Evolution of Cancer Cells

H. Heng, S. Mukherjee, M. Frenkel-Morgenstern, 2021, Cancers.

Cloning and chromosomal mapping of three novel genes, GPR9, GPR10, and GPR14, encoding receptors related to interleukin 8, neuropeptide Y, and somatostatin receptors.

H. Heng, L. Tsui, A. Marchese, 1995, Genomics.

High resolution free chromatin/DNA fiber fluorescent in situ hybridization.

H. Heng, L. Tsui, 1998, Journal of chromatography. A.

High Resolution Fiber-Fluorescence In Situ Hybridization.

H. Heng, C. Ye, 2017, Methods in molecular biology.

High‐Resolution FISH Analysis

H. Heng, L. Tsui, B. Windle, 1995, Current protocols in human genetics.

Isolation of three novel human genes encoding G protein-coupled receptors.

H. Heng, L. Tsui, S. George, 1995, DNA and cell biology.

Interrogating the transgenic genome: development of an interspecies tiling array

H. Heng, S. Krawetz, A. Platts, 2011, Systems biology in reproductive medicine.

Cloning and expression analysis of a novel WD repeat gene, WDR3, mapping to 1p12-p13.

H. Heng, A. Stewart, R. Hawley, 1999, Genomics.

Identification and characterization of human genes encoding Hprp3p and Hprp4p, interacting components of the spliceosome.

H. Heng, L. Tsui, J. Woolford, 1997, Human molecular genetics.

Chapter 5 – The Genomic Landscape of Cancers

Henry H. Heng, H. Heng, 2017 .

The evolutionary mechanism of cancer

H. Heng, Guo Liu, S. Bremer, 2010, Journal of cellular biochemistry.

Sequence Analysis and Chromosomal Localization of Human Cap Z

S. Scherer, H. Heng, L. Tsui, 1995, The Journal of Biological Chemistry.

Dynamic stromal‐epithelial interactions during progression of MCF10DCIS.com xenografts

H. Heng, J. Rak, F. Miller, 2007, International journal of cancer.

Overexpression of Cyclin D1 Promotes Tumor Cell Growth and Confers Resistance to Cisplatin-Mediated Apoptosis in an Elastase-myc Transgene–Expressing Pancreatic Tumor Cell Line

H. Heng, Sanjeev Banerjee, F. Sarkar, 2005, Clinical Cancer Research.

Rad51 immunocytology in rat and mouse spermatocytes and oocytes

David J. Chen, H. Heng, Zhiyuan Shen, 1997, Chromosoma.

Human Chromosome 7: DNA Sequence and Biology

Junjun Zhang, Nazneen Rahman, Alexander K. Hudek, 2003, Science.

The gene‐centric concept: A new liability?

H. Heng, 2008, BioEssays : news and reviews in molecular, cellular and developmental biology.

Specific and redundant functions of Gli2 and Gli3 zinc finger genes in skeletal patterning and development.

H. Heng, L. Tsui, D. Zinyk, 1997, Development.

Structure and chromosomal localization of the human constitutive endothelial nitric oxide synthase gene.

S. Scherer, H. Heng, L. Tsui, 1993, The Journal of biological chemistry.

Heterogeneity-mediated cellular adaptation and its trade-off: searching for the general principles of diseases.

Henry H Heng, H. Heng, 2017, Journal of evaluation in clinical practice.

Recent segmental and gene duplications in the mouse genome

Junjun Zhang, Michael D. Wilson, Joseph Cheung, 2003, Genome Biology.

Molecular Cytogenetics: the first impact factor (2.36)

H. Heng, T. Liehr, Y. Yurov, 2013, Molecular Cytogenetics.

Assignment of the human homolog of mouse Dlx3 to Chromosome 17q21.3-q22 by analysis of somatic cell hybrids and fluorescence in situ hybridization

S. Scherer, H. Heng, L. Tsui, 1995, Mammalian Genome.

Further illusions: On key evolutionary mechanisms that could never fit with Modern Synthesis.

H. Heng, R. Crkvenjakov, 2021, Progress in biophysics and molecular biology.

Cloning and mapping of a cDNA for methionine synthase reductase, a flavoprotein defective in patients with homocystinuria.

Aaron D. Wilson, S. Scherer, H. Heng, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Identification of a human LIM-Hox gene, hLH-2, aberrantly expressed in chronic myelogenous leukaemia and located on 9q33-34.1.

H. Heng, L. Tsui, M. Minden, 1996, Oncogene.

Evolutionary mechanism unifies the hallmarks of cancer

H. Heng, S. Horne, Sarah A Pollick, 2015, International journal of cancer.

Structure of the murine MPTP-PEST gene: genomic organization and chromosomal mapping.

H. Heng, M. Tremblay, A. Charest, 1995, Genomics.

Direct detection of expanded trinucleotide repeats using PCR and DNA hybridization techniques.

H. Heng, L. Tsui, J. Kennedy, 1996, American journal of medical genetics.

Released chromatin or DNA fiber preparations for high-resolution fiber FISH.

H. Heng, 2000, Methods in molecular biology.

From free chromatin analysis to high resolution fiber FISH*

H. Heng, Xiao-Mei Shi, 1997, Cell Research.

Expression analysis and chromosomal assignment of the human SFRS5/SRp40 gene.

H. Heng, L. Tsui, R. Mcinnes, 1997, Genomics.

Discovery of three novel orphan G-protein-coupled receptors.

H. Heng, B. O'dowd, S. George, 1999, Genomics.

Localization of two metabotropic glutamate receptor genes, GRM3 and GRM8, to human chromosome 7q.

S. Scherer, H. Heng, L. Tsui, 1996, Genomics.

Missing heritability and stochastic genome alterations

H. Heng, 2010, Nature Reviews Genetics.

Heterogeneity of Cell Death

Batoul Y. Abdallah, H. Heng, M. Kurkinen, 2013, Cytogenetic and Genome Research.

Simultaneous Fluorescence Immunostaining and FISH

H. Heng, Guo Liu, S. Bremer, 2009 .

Refined localization of the asparagine synthetase gene (ASNS) to chromosome 7, region q21.3, and characterization of the somatic cell hybrid line 4AF/106/KO15.

S. Scherer, H. Heng, L. Tsui, 1994, Cytogenetics and cell genetics.

Isolation of P1 bacteriophage clones containing large contiguous segments of the human and mouse loci for the T-cell coreceptor molecule CD8.

H. Heng, L. Tsui, J. Parnes, 1994, Genetic analysis, techniques and applications.

Rad6 overexpression induces multinucleation, centrosome amplification, abnormal mitosis, aneuploidy, and transformation.

H. Heng, D. Visscher, A. Lyakhovich, 2002, Cancer research.

The human beta-defensin-1 and alpha-defensins are encoded by adjacent genes: two peptide families with differing disulfide topology share a common ancestry.

H. Heng, T. Ganz, C. Zhao, 1997, Genomics.

Chromosomal Instability (CIN) in Cancer

H. Heng, S. Horne, C. Ye, 2015 .

Cloning and chromosomal mapping of four putative novel human G-protein-coupled receptor genes.

H. Heng, L. F. Kolakowski, B. O'dowd, 1997, Gene.

A novel family of repeat sequences in the mouse genome responsive to retinoic acid

H. Heng, W. Wurst, A. Bernstein, 1996, Mammalian Genome.

Human microbiome and environmental disease

H. Heng, Gary Zhang, 2017 .

Sperm nuclear matrix association of the PRM1-->PRM2-->TNP2 domain is independent of Alu methylation.

H. Heng, C. Rubin, C. Ye, 2001, Molecular human reproduction.

Cloning and characterization of additional members of the G protein-coupled receptor family.

H. Heng, P. Seeman, B. O'dowd, 2000, Biochimica et biophysica acta.

Sequential molecular and cellular events during neoplastic progression: a mouse syngeneic ovarian cancer model.

Eva M. Schmelz, H. Heng, P. Roberts, 2005, Neoplasia.

The Mechanisms of How Genomic Heterogeneity Impacts Bio-Emergent Properties: The Challenges for Precision Medicine

Zachary Armstrong, Henry H.Q. Heng, Guo Liu, 2019, Embracing Complexity in Health.

Cancer genome evolution

Batoul Y. Abdallah, H. Heng, S. Horne, 2015 .

Localization of the human gene encoding the 13.3-kDa subunit of mitochondrial complex III (UQCRB) to 8q22 by in situ hybridization.

H. Heng, L. Tsui, B. Robinson, 1996, Cytogenetics and cell genetics.

Chromosomal localization of the human gene encoding the 51-kDa subunit of mitochondrial complex I (NDUFV1) to 11q13.

H. Heng, L. Tsui, K. Schappert, 1993, Genomics.

Unstable genomes elevate transcriptome dynamics

Batoul Y. Abdallah, H. Heng, S. Krawetz, 2014, International journal of cancer.

Chromosomal instability and transcriptome dynamics in cancer

Batoul Y. Abdallah, H. Heng, S. Horne, 2013, Cancer and Metastasis Reviews.

Genome in Development and Cloning

H. Heng, N. Kolas, C. Hoog, 2004 .

Rad 6 Overexpression Induces Multinucleation , Centrosome Amplification , Abnormal Mitosis , Aneuploidy , and Transformation 1

H. Heng, D. Visscher, A. Lyakhovich, 2002 .

Receptor-binding, tyrosine phosphorylation and chromosome localization of the mouse SH2-containing phosphotyrosine phosphatase Syp.

H. Heng, L. Tsui, T. Pawson, 1994, Oncogene.

Tissue distribution, genomic structure, and chromosome mapping of mouse and human eukaryotic initiation factor 4E-binding proteins 1 and 2.

H. Heng, S. Hanash, A. Gingras, 1996, Genomics.

Bio-Complexity: Challenging Reductionism

Henry H.Q. Heng, H. Heng, Henry H.Q. Heng, 2013 .

Genetic and epigenetic heterogeneity in cancer: the ultimate challenge for drug therapy.

H. Heng, S. Bremer, J. Stevens, 2010, Current drug targets.

Refined mapping of the GM2 activator protein (GM2A) locus to 5q31.3-q33.1, distal to the spinal muscular atrophy locus.

H. Heng, L. Tsui, D. Mahuran, 1993, Genomics.

Debating Cancer:The Paradox in Cancer Research

H. Heng, 2015 .

Linking Gulf War Illness to Genome Instability, Somatic Evolution, and Complex Adaptive Systems

Sarah M. Regan, H. Heng, Guo Liu, 2018 .

Heterogeneity Mediated System Complexity: The Ultimate Challenge for Studying Common and Complex Diseases

Batoul Y. Abdallah, H. Heng, Kezhong Zhang, 2016 .

Insights on processes of evolutionary tumor growth

H. Heng, S. Horne, J. Stevens, 2017 .

The contribution of genomic heterogeneity. Preface.

H. Heng, 2013, Cytogenetic and genome research.

The combination of SKY and specific loci detection with FISH or immunostaining

H. Heng, P. Moens, M. Hughes, 2001, Cytogenetic and Genome Research.

The genes for the alpha and beta subunits of the mitochondrial trifunctional protein are both located in the same region of human chromosome 2p23.

H. Heng, C. Roe, B. Z. Yang, 1996, Genomics.

Differential expression of a basic helix-loop-helix phosphoprotein gene, G0S8, in acute leukemia and localization to human chromosome 1q31.

H. Heng, L. Tsui, M. Minden, 1995, Leukemia.

Signal transducer and activator of transcription-3 is required in hypothalamic agouti-related protein/neuropeptide Y neurons for normal energy homeostasis.

H. Heng, M. Low, S. Akira, 2008, Endocrinology.

Assignment of mouse fibroblast growth factor 10 (Fgf10) gene to the telomeric region of chromosome 13.

H. Heng, L. Tsui, M. Crackower, 1998, Genomics.

Cancer genome sequencing: the challenges ahead.

H. Heng, 2007, BioEssays : news and reviews in molecular, cellular and developmental biology.

Cancer research meets evolutionary biology

Santa Fe Institute, T. Vincent, C. Findlay, 2009, Evolutionary applications.

Mapping of the human HPRP3 and HPRP4 genes encoding U4/U6-associated splicing factors to chromosomes 1q21.1 and 9q31-q33.

H. Heng, J. Hu, A. Wang, 1998, Genomics.

High‐Resolution FISH Analysis

H. Heng, L. Tsui, B. Windle, 1995 .

Spectral karyotyping (SKY) of mouse meiotic chromosomes.

H. Heng, P. Moens, M. Hughes, 2001, Genome.

Heng Reductionism The Conflict Between Complex Systems and Correction

H. Heng, 2008 .

Heterogeneity-mediated cellular adaptation and its trade-off: searching for the general principles of diseases.

H. Heng, 2017, Journal of evaluation in clinical practice.

SEX REDUCES GENETIC VARIATION: A MULTIDISCIPLINARY REVIEW

H. Heng, Root Gorelick, 2011, Evolution; international journal of organic evolution.