B. Migeon

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Adrenoleukodystrophy: evidence for X linkage, inactivation, and selection favoring the mutant allele in heterozygous cells.

B. Migeon, H. Moser, A. Moser, 1981, Proceedings of the National Academy of Sciences of the United States of America.

Sex difference in methylation of single-copy genes in human meiotic germ cells: Implications for X chromosome inactivation, parental imprinting, and origin of CpG mutations

D. J. Driscoll, B. Migeon, 1990, Somatic cell and molecular genetics.

Studies of X-chromosome inactivation in trisomies.

B. Migeon, P. Jacobs, 1989, Cytogenetics and cell genetics.

Females Are Mosaics: X Inactivation and Sex Differences in Disease

B. Migeon, 2007 .

Short arm deletions in group E and chromosomal "deletion" syndromes.

B. Migeon, 1966, The Journal of pediatrics.

Clusters of CpG dinucleotides implicated by nuclease hypersensitivity as control elements of housekeeping genes

B. Migeon, S. Wolf, 1985, Nature.

Asynchronous replication of homologous loci on human active and inactive X chromosomes.

B. Migeon, M. Schmidt, 1990, Proceedings of the National Academy of Sciences of the United States of America.

Studies of X chromosome DNA methylation in normal human cells

B. Migeon, S. Wolf, Barbara R. Migeon, 1982, Nature.

Comparison of factor IX methylation on human active and inactive X chromosomes: implications for X inactivation and transcription of tissue‐specific genes.

B. Migeon, D. Kaslow, C. Cullen, 1986, The EMBO journal.

Expression of the G6PD locus on the human X chromosome is associated with demethylation of three CpG islands within 100 kb of DNA.

B. Migeon, D. Toniolo, G. Martini, 1988, The EMBO journal.

DNA methylation: Molecular biology and biological significance

B. Migeon, Barbara R. Migeon, 1993 .

Quantitation of contact-feeding between somatic cells in culture.

B. Migeon, C. Corsaro, C. M. Corsaro, 1975, Experimental cell research.

Effect of ouabain resistance on human diploid fibroblasts carrying other genetic variants.

B. Migeon, C. Corsaro, 1975, Experimental Cell Research.

Comparison of contact-mediated communication in normal and transformed human cells in culture.

B. Migeon, C. Corsaro, C. M. Corsaro, 1977, Proceedings of the National Academy of Sciences of the United States of America.

Deficient transcription of XIST from tiny ring X chromosomes in females with severe phenotypes.

B. Migeon, J. Axelman, P. Jacobs, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Genomic imprinting (development 1990 supplement)

B. Migeon, D. Parkin, 1991 .

X inactivation, female mosaicism, and sex differences in renal diseases.

B. Migeon, 2008, Journal of the American Society of Nephrology : JASN.

Reflections on the history of genetic medicine at Johns Hopkins University

B. Migeon, H. Kazazian, 2021, American journal of medical genetics. Part A.

Signal sequence and DNA-mediated expression of human lysosomal alpha-galactosidase A.

B. Migeon, S. Tsuji, E. Ginns, 1987, European journal of biochemistry.

Frequent derepression of G6PD and HPRT on the marsupial inactive X chromosome associated with cell proliferation in vitro.

B. Migeon, J. Axelman, S. Jan de Beur, 1989, Experimental cell research.

Human X inactivation center induces random X chromosome inactivation in male transgenic mice.

B. Migeon, R. Reeves, L. Call, 1999, Genomics.

Genetic disorders of male sexual differentiation.

B. Migeon, C. Migeon, K. Fichman, 1980, Advances in human genetics.

Interferon Production and Action in Mouse, Hamster, and Somatic Hybrid Mouse-Hamster Cells

B. Migeon, D. H. Carver, D. Seto, 1968, Science.

Molecular studies of marsupial X chromosomes reveal limited sequence homology of mammalian X-linked genes.

B. Migeon, D. Kaslow, M. Zollo, 1987, Genomics.

Selection against lethal alleles in females heterozygous for incontinentia pigmenti.

B. Migeon, J. Axelman, G. Mitchell, 1989, American journal of human genetics.

D-valine as a selective agent for normal human and rodent epithelial cells in culture

S. Gilbert, B. Migeon, 1975, Cell.

The XIST locus replicates late on the active X, and earlier on the inactive X based on FISH DNA replication analysis of somatic cell hybrids

B. Torchia, B. Migeon, B. Torchia, 1995, Somatic cell and molecular genetics.

Translocation of the nucleolus organizer region to the human X chromosome.

B. Migeon, J. Axelman, G. Stetten, 1986, American journal of human genetics.

DNA restriction endonuclease analysis for localization of human beta- and delta-globin genes on chromosome 11.

B. Migeon, A. F. Scott, J. Phillips, 1979, Proceedings of the National Academy of Sciences of the United States of America.

Differential X reactivation in human placental cells: implications for reversal of X inactivation.

B. Migeon, J. Axelman, P. Jeppesen, 2005, American journal of human genetics.

Low-copy-number human transgene is recognized as an X inactivation center in mouse ES cells, but fails to induce cis-inactivation in chimeric mice.

B. Migeon, P. Jeppesen, A. Chowdhury, 2001, Genomics.

Characterization of a cloned DNA sequence that is present at centromeres of all human autosomes and the X chromosome and shows polymorphic variation.

B. Migeon, E. Jabs, S. Wolf, 1984, Proceedings of the National Academy of Sciences of the United States of America.

The severe phenotype of females with tiny ring X chromosomes is associated with inability of these chromosomes to undergo X inactivation.

B. Migeon, P. Jeppesen, S. Luo, 1994, American journal of human genetics.

Somatic cell hybrids: applications relevant to genetic disease.

B. Migeon, 1971, The Journal of pediatrics.

Genetic Inactivation of the α-Galactosidase Locus in Carriers of Fabry's Disease

B. Migeon, G. Romeo, 1970, Science.

Genetic inactivation of the alpha-galactosidase locus in carriers of Fabry's disease.

B. Migeon, G. Romeo, 1970, Science.

Barton Childs 1916–2010

B. Migeon, 2010, Nature Genetics.

Centromeric inactivation in a dicentric human Y;21 translocation chromosome

C. Tyler-Smith, B. Migeon, J. Axelman, 1997, Chromosoma.

ANDROGEN RECEPTORS AND METABOLISM IN CULTURED HUMAN FETAL FIBROBLASTS

B. Migeon, C. Sultan, C. Migeon, 1980, Pediatric Research.

Species differences in TSIX/Tsix reveal the roles of these genes in X-chromosome inactivation.

B. Migeon, A. Chowdhury, Catherine H. Lee, 2002, American journal of human genetics.

Studies of the locus for androgen receptor: localization on the human X chromosome and evidence for homology with the Tfm locus in the mouse.

B. Migeon, J. Axelman, C. Migeon, 1981, Proceedings of the National Academy of Sciences of the United States of America.

X chromosome inactivation: theme and variations

B. Migeon, 2003, Cytogenetic and Genome Research.

Human and mouse hypoxanthine-guanine phosphoribosyltransferase: dimers and tetramers.

B. Migeon, G. Johnson, L. R. Eisenberg, 1979, Science.

X inactivation in triploidy and trisomy: the search for autosomal transfactors that choose the active X

B. Migeon, P. Jacobs, G. Stetten, 2008, European Journal of Human Genetics.

Complex chromosome rearrangements:Report of a new case and literature review

B. Migeon, G. Thomas, G. Pai, 1980, Clinical genetics.

Incomplete X chromosome dosage compensation in chorionic villi of human placenta.

B. Migeon, J. Axelman, D. Kaslow, 1985, Proceedings of the National Academy of Sciences of the United States of America.

Fragile X syndrome: search for phenotypic manifestations at loci for hypoxanthine phosphoribosyltransferase and glucose-6-phosphate dehydrogenase.

B. Migeon, C. Mareni, Cristina Mareni, 1981, American journal of human genetics.

Genetic complementation after fusion of Tay-Sachs and Sandhoff cells

B. Migeon, J. Axelman, C. Miller, 1974, Nature.

Assignment of the haemophilia B (Factor IX) locus to the q26‐qter region of the X chromosome

B. Migeon, I. Craig, Y. Boyd, 1984, Annals of human genetics.

Severe hemophilia A in a female by cryptic translocation: order and orientation of factor VIII within Xq28.

B. Migeon, J. Axelman, S. Antonarakis, 1993, Genomics.

Localization of loci for hypoxanthine phosphoribosyltransferase and glucose-6-phosphate dehydrogenase and biochemical evidence of nonrandom X chromosome expression from studies of a human X-autosome translocation.

B. Migeon, C. Mareni, G. Pai, 1980, Proceedings of the National Academy of Sciences of the United States of America.

Mechanism of origin of complete hydatidiform moles

Patricia A. Jacobs, B. Migeon, P. Jacobs, 1980, Nature.

Selection and cell communication as determinants of female phenotype.

B. Migeon, 1978, Basic life sciences.

HYBRIDIZATION OF MAMMALIAN CELLS *

B. Migeon, 1970 .

Gene expression in euploid human hybrid cells: Ouabain resistance is codominant

B. Migeon, C. Corsaro, C. M. Corsaro, 1978, Somatic cell genetics.

Locus on human X chromosome for dihydrotestosterone receptor and androgen insensitivity.

B. Migeon, C. Migeon, W. Meyer, 1975, Proceedings of the National Academy of Sciences of the United States of America.

Human Thymidine Kinase Gene Locus: Assignment to Chromosome 17 in a Hybrid of Man and Mouse Cells

B. Migeon, D. Miller, W. R. Breg, 1971, Science.

Artefactual Chromatid Aberrations in Untreated and X-ray-treated Human Lymphocytes

B. Migeon, T. Merz, 1964, Nature.

Second trimester prenatal diagnosis of epignathus teratoma in ring X chromosome mosaicism with inactive ring X chromosome.

B. Migeon, J. Fryns, P. Moerman, 2001, Annales de genetique.

Stability of X Chromosomal Inactivation in Human Somatic Cells

B. Migeon, 1972, Nature.

X-Linked Hypoxanthine-Guanine Phosphoribosyl Transferase Deficiency: Heterozygote Has Two Clonal Populations

B. Migeon, B. Childs, W. Nyhan, 1968, Science.

X-linked hypoxanthine-guanine phosphoribosyl transferase deficiency: Detection of heterozygotes by selective medium

B. Migeon, 1970, Biochemical Genetics.

Methylation of the hypoxanthine phosphoribosyltransferase locus on the human X chromosome: implications for X-chromosome inactivation.

B. Migeon, T. Friedmann, D. Jolly, 1984, Proceedings of the National Academy of Sciences of the United States of America.

Phenotypic heterogeneity within clones of fetal human cells.

S. Gilbert, B. Migeon, J. Axelman, 1981, American journal of human genetics.

The Prenatal Diagnosis of Adrenoleukodystrophy. Demonstration of Increased Hexacosanoic Acid Levels in Cultured Amniocytes and Fetal Adrenal Gland

B. Migeon, H. Moser, A. Moser, 1982, Pediatric Research.

Renal enzymes in kidney cells selected by D‐valine medium

S. Gilbert, B. Migeon, 1977, Journal of cellular physiology.

Differential expression of steroid sulphatase locus on active and inactive human X chromosome

T. Mohandas, L. Shapiro, B. Migeon, 1982, Nature.

Clonal evolution in human lymphoblast cultures.

B. Migeon, J. Axelman, G. Stetten, 1988, American journal of human genetics.

An overview of X inactivation based on species differences.

B. Migeon, 2016, Seminars in cell & developmental biology.

Chromatin loop structure of the human X chromosome: relevance to X inactivation and CpG clusters

B. Migeon, A. Beggs, 1989, Molecular and cellular biology.

Chromatin LoopStructure oftheHumanX Chromosome: Relevance toX Inactivation andCpGClusters

B. Migeon, Alan H. BEGGStAND, 1989 .

INSIGHTS INTO G6PD REGULATION FROM STUDIES OF X DOSAGE COMPENSATION

B. Migeon, 1986 .

Localization of glucose-6-phosphate dehydrogenase in mouse and man by in situ hybridization: evidence for a single locus and transposition of homologous X-linked genes.

B. Migeon, D. Toniolo, G. Martini, 1985, Cytogenetics and cell genetics.

Complete concordance between glucose-6-phosphate dehydrogenase activity and hypomethylation of 3' CpG clusters: implications for X chromosome dosage compensation.

B. Migeon, J. Axelman, D. Toniolo, 1984, Nucleic acids research.

Derepression with decreased expression of the G6PD locus on the inactive X chromosome in normal human cells

B. Migeon, J. Axelman, C. Mareni, 1982, Cell.

Stability of the “two active X” phenotype in triploid somatic cells

B. Migeon, J. A. Sprenkle, T. T. Do, 1979, Cell.

Evidence for two active X chromosomes in germ cells of female before meiotic entry

B. Migeon, K. Jelalian, 1977, Nature.

Familial skewed X inactivation and X-linked mutations: unbalanced X inactivation is a powerful means to ascertain X-linked genes that affect cell proliferation.

B. Migeon, C. Haisley-Royster, 1998, American journal of human genetics.

Is Tsix repression of Xist specific to mouse?

B. Migeon, 2003, Nature Genetics.

Human-Mouse Somatic Cell Hybrids with Single Human Chromosome (Group E): Link with Thymidine Kinase Actvity

B. Migeon, C. Miller, 1968, Science.

X-chromosome inactivation: molecular mechanisms and genetic consequences.

B. Migeon, 1994, Trends in genetics : TIG.

Insights into X chromosome inactivation from studies of species variation, DNA methylation and replication, and vice versa.

B. Migeon, 1990, Genetical research.

Severe phenotypes associated with inactive ring X chromosomes.

B. Migeon, G. Raymond, J. Giltay, 2000, American journal of medical genetics.

Molecular characterization of tiny ring X chromosomes from females with functional X chromosome disomy and lack of cis X inactivation.

B. Migeon, G. Pai, M. Jani, 1995, Genomics.

Identification of TSIX, encoding an RNA antisense to human XIST, reveals differences from its murine counterpart: implications for X inactivation.

B. Migeon, A. Chowdhury, I McIntosh, 2001, American journal of human genetics.

DNA replication analysis of FMR1, XIST, and factor 8C loci by FISH shows nontranscribed X-linked genes replicate late.

B. Migeon, L. Call, B. Torchia, 1994, American journal of human genetics.

Evidence for a relationship between DNA methylation and DNA replication from studies of the 5-azacytidine-reactivated allocyclic X chromosome.

B. Migeon, S. Wolf, M. Schmidt, 1985, Experimental cell research.

Methylation status of genes flanking the fragile site in males with the fragile-X syndrome: a test of the imprinting hypothesis.

B. Migeon, A. Reiss, M. Khalifa, 1990, American journal of human genetics.

DNA methylation stabilizes X chromosome inactivation in eutherians but not in marsupials: evidence for multistep maintenance of mammalian X dosage compensation.

B. Migeon, D. Kaslow, 1987, Proceedings of the National Academy of Sciences of the United States of America.

Signal sequence and DNA-mediated expression of human lysosomal alpha-galactosidase A.

B. Migeon, S. Tsuji, E. Ginns, 1987, European journal of biochemistry.

The single active X in human cells: evolutionary tinkering personified

B. Migeon, 2011, Human Genetics.

The Barr body is a looped X chromosome formed by telomere association.

B. Migeon, C. Cargile, C. B. Cargile, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Effect of intercellular communication on the selection of intraspecific human hybrids in HAT and ouabain

B. Migeon, C. Corsaro, C. M. Corsaro, 1978, Somatic cell genetics.

Inactivation: Studies of Fetal Membranes Heterozygous for Glucose-6-Phosphate Dehydrogenase

B. Migeon, T. T. Do, 2006 .

In search of nonrandom X inactivation: studies of the placenta from newborns heterozygous for glucose-6-phosphate dehydrogenase.

B. Migeon, T. T. Do, 1978, Basic life sciences.

Lack of X inactivation associated with maternal X isodisomy: evidence for a counting mechanism prior to X inactivation during human embryogenesis.

D. J. Driscoll, B. Migeon, J. Axelman, 1996, American journal of human genetics.

BLOOD-GROUP CHIMÆRISM WITH DOWN'S SYNDROME

B. Migeon, W. Bias, 1967 .

Selected bibliography of Susumu Ohno

C. Disteche, B. Migeon, B. Kerem, 1998, Cytogenetic and Genome Research.

The role of X inactivation and cellular mosaicism in women's health and sex-specific diseases.

B. Migeon, 2006, JAMA.

The Hunter syndrome in females: is there an autosomal recessive form of iduronate sulfatase deficiency?

B. Migeon, C. Epstein, I. Liebaers, 1977, American journal of human genetics.

X-linked diseases: susceptible females

B. Migeon, 2020, Genetics in Medicine.

Studies of X inactivation and isodisomy in twins provide further evidence that the X chromosome is not involved in Rett syndrome.

B. Migeon, S. Naidu, B. Schmeckpeper, 1995, American journal of human genetics.

RECIPROCAL (D;E) TRANSLOCATION: EUPLOID TRANSMISSION IN THREE GENERATIONS.

B. Migeon, W. Young, 1964, Bulletin of the Johns Hopkins Hospital.

Molecular characterization of a deleted X chromosome (Xq13.3-Xq21.31) exhibiting random X inactivation

B. Migeon, J. Axelman, D. Dungy, 1995, Somatic cell and molecular genetics.

X-linked Hunter syndrome: the heterozygous phenotype in cell culture.

B. Migeon, I. Liebaers, E. Neufeld, 1977, American Journal of Human Genetics.

Enrichment of human heterokaryons by ficoll gradient for complementation analysis of iduronate sulfatase deficiency

B. Migeon, L. R. Eisenberg, Barbara R. Migeon, 1979, Somatic cell genetics.

The occurrence of new mutants in the X-linked recessive Lesch-Nyhan disease.

B. Migeon, J. Felsenstein, U. Francke, 1976, American journal of human genetics.

Silencing XIST on the future active X: Searching human and bovine preimplantation embryos for the repressor.

B. Migeon, M. Aksit, B. Roelen, 2022, European journal of human genetics : EJHG.

Silencing XIST on the future active X: Searching human and bovine preimplantation embryos for the repressor

B. Migeon, M. Aksit, B. Roelen, 2021, bioRxiv.

Non-random X chromosome inactivation in mammalian cells

B. Migeon, 1998, Cytogenetic and Genome Research.

Embryonic loss of human females with partial trisomy 19 identifies region critical for the single active X

Michael A. Beer, B. Migeon, M. Beer, 2017, bioRxiv.

The Non-random Location of Autosomal Genes That Participate in X Inactivation

B. Migeon, 2019, bioRxiv.

Choosing the Active X: The Human Version of X Inactivation.

B. Migeon, 2017, Trends in genetics : TIG.

Why females are mosaics, X-chromosome inactivation, and sex differences in disease.

B. Migeon, 2007, Gender medicine.

The human NTT gene: identification of a novel 17-kb noncoding nuclear RNA expressed in activated CD4+ T cells.

R. Siliciano, B. Migeon, B. Torchia, 1997, Genomics.

Effect of ageing on reactivation of the human X-linked HPRT locus

B. Migeon, J. Axelman, A. Beggs, 1988, Nature.

Complete reactivation of X chromosomes from human chorionic villi with a switch to early DNA replication.

B. Migeon, J. Axelman, M. Schmidt, 1986, Proceedings of the National Academy of Sciences of the United States of America.

Titles and abstracts of scientific reports ignore variation among species

B. Migeon, 2014, eLife.

Isolation and characterization of cloned DNA sequences that hybridize to the human X chromosome

B. Migeon, C. Mareni, S. Wolf, 1980, Cell.

In search of non-random X inactivation: studies of fetal membranes heterozygous for glucose-6-phosphate dehydrogenase.

B. Migeon, T. T. Do, 1979, American journal of human genetics.

Stochastic gene expression and chromosome interactions in protecting the human active X from silencing by XIST

B. Migeon, 2020, Nucleus.

Studies of skin fibroblasts from 10 families with HGPRT deficiency, with reference in X-chromosomal inactivation.

B. Migeon, 1971, American journal of human genetics.

Non–random loss of human markers from man–mouse somatic cell hybrids

B. Migeon, R. Norum, 1974, Nature.

XIST expression is repressed when X inactivation is reversed in human placental cells: A model for study ofXIST regulation

B. Torchia, B. Migeon, Shengyuan Luo, 1995, Somatic cell and molecular genetics.

DNA methylation of the fragile X locus in somatic and germ cells during fetal development: Relevance to the fragile X syndrome and X inactivation

B. Migeon, A. Reiss, Shengyuan Luo, 1993, Somatic cell and molecular genetics.

Concerning the role of X-inactivation and DNA methylation in fragile X syndrome.

B. Migeon, 1992, American journal of medical genetics.

B. Migeon, W. Earnshaw, 2004, Chromosoma.

TheBarrbodyisalooped X chromosome formedby telomere association

B. Migeon, 1991 .

The nature of thymidine kinase in the human-mouse hybrid cell

B. Migeon, Sara W. Smith, Cheryl L. Leddy, 1969, Biochemical Genetics.

Role of DNA methylation in X inactivation and the fragile X syndrome

B. Migeon, 1993 .

Characterization of reiterated human DNA with respect to mammalian X chromosome homology

B. Migeon, E. Jabs, S. Wolf, 1984, Somatic cell and molecular genetics.

FAMILIAL VARIANT AUTOSOMES: NEW HUMAN CYTOGENETIC MARKERS.

B. Migeon, 1965, Bulletin of the Johns Hopkins Hospital.

Programmed demethylation in CpG islands during human fetal development

D. J. Driscoll, B. Migeon, M. Holland, 1991, Somatic cell and molecular genetics.

X-linked diseases: susceptible females

B. Migeon, 2020, Genetics in Medicine.

Theme 2

B. Migeon, 2006 .

Evidence for the inactivation of an X chromosome early in the development of the human female.

B. Migeon, J. F. Kennedy, 1975, American journal of human genetics.

Adrenoleukodystrophy: studies of the phenotype, genetics and biochemistry.

B. Migeon, H. Moser, A. Moser, 1980, The Johns Hopkins medical journal.

Sex Differences in Disease

B. Migeon, 2013 .

Hybridization of somatic cells derived from mouse and Syrian hamster: Evolution of karyotype and enzyme studies

B. Migeon, 1968, Biochemical Genetics.

Unusual (CGG)n expansion and recombination in a family with fragile X and DiGeorge syndrome.

B. Migeon, K. Davies, J. Crolla, 1995, Journal of medical genetics.

Haptoglobin: a locus on the D1 chromosome?

B. Migeon, W. Bias, 1967, American journal of human genetics.

Familial nonrandom inactivation linked to the X inactivation centre in heterozygotes manifesting haemophilia A

B. Migeon, F. Corsolini, M. Bicocchi, 2005, European Journal of Human Genetics.

Contact-mediated communication of ouabain resistance in mammalian cells in culture

B. Migeon, C. Corsaro, 1977, Nature.

Biochemical and genetic aspects of mental retardation.

B. Migeon, J. Menkes, 1966, Annual Review of Medicine.

Reactivation of X-linked genes in human fibroblasts transformed by origin-defective SV40

B. Migeon, J. Axelman, A. Beggs, 1986, Somatic cell and molecular genetics.

Studies of human-mouse cell hybrids with respect to X-chromosome inactivation.

B. Migeon, J. A. Sprenkle, T. T. Do, 1978, Basic life sciences.

Heredity under the microscope: Chromosomes and the study of the human genomeSorayadeChadarevianUniversity of Chicago Press, 2020

B. Migeon, 2020, The FASEB Journal.

Implications for X-chromosome regulation from studies of human X-chromosome DNA.

B. Migeon, S. Wolf, 1983, Cold Spring Harbor symposia on quantitative biology.

Localization of G6PD and HPRT to different arms of the X chromosome of the North American marsupial (Didelphis virginiana) by in situ hybridization and deletion mapping: evolutionary significance.

D. J. Driscoll, B. Migeon, 1988, Genomics.

Unreliability of the microcomplement fixation method for Xga typing of cultured fibroblasts.

B. Migeon, W. Bias, S. H. Hsu, 1976, Birth defects original article series.

Selection of epithelial cells in culture by D-valine medium.

B. Migeon, 1980, Birth defects original article series.

Thyroxin, Satellite Association and Trisomy

B. Migeon, T. Merz, T. Prempree, 1966, Nature.

Hybridization of mammalian somatic cells.

B. Migeon, B. Childs, 1970, Progress in medical genetics.

The postulated X-inactivation center at Xq27 is most reasonably explained by ascertainment bias: heterozygous expression of recessive mutations is a powerful means of detecting unbalanced X inactivation.

B. Migeon, 1993, American journal of human genetics.