D. Moerman

发表

Assessing normal embryogenesis in Caenorhabditis elegans using a 4D microscope: variability of development and regional specification.

H. Schnabel, R. Schnabel, H. Hutter, 1997, Developmental biology.

The molecular signature and cis-regulatory architecture of a C. elegans gustatory neuron.

Steven J. M. Jones, Monica C. Sleumer, D. Moerman, 2007, Genes & development.

Determining the Sub-Cellular Localization of Proteins within Caenorhabditis elegans Body Wall Muscle

D. Moerman, B. Meissner, L. Ségalat, 2011, PloS one.

High-Throughput In Vivo Analysis of Gene Expression in Caenorhabditis elegans

Steven J. M. Jones, R. Schnabel, D. Moerman, 2007, PLoS biology.

Genome-scale analysis of in vivo spatiotemporal promoter activity in Caenorhabditis elegans

Albert-László Barabási, Marc Vidal, César A Hidalgo, 2007, Nature Biotechnology.

Gene expression profiling of cells, tissues, and developmental stages of the nematode C. elegans.

D L Riddle, D. Moerman, E. Sonnhammer, 2003, Cold Spring Harbor symposia on quantitative biology.

Using C. elegans Forward and Reverse Genetics to Identify New Compounds with Anthelmintic Activity

D. Moerman, G. Giaever, Mark D. Mathew, 2016, PLoS neglected tropical diseases.

The million mutation project: A new approach to genetics in Caenorhabditis elegans

Emily H Turner, J. Shendure, L. Hillier, 2013, Genome research.

Critical Residues of the Caenorhabditis elegans unc-2 Voltage-Gated Calcium Channel That Affect Behavioral and Physiological Properties

D. Moerman, E. Mathews, T. Snutch, 2003, The Journal of Neuroscience.

Remarkably Divergent Regions Punctuate the Genome Assembly of the Caenorhabditis elegans Hawaiian Strain CB4856

L. B. Snoek, L. Hillier, R. Waterston, 2015, Genetics.

Identification of genes expressed in the hermaphrodite germ line of C. elegans using SAGE

Steven J. M. Jones, D. Moerman, Kim Wong, 2009, BMC Genomics.

Whole-Genome Profiling of Mutagenesis in Caenorhabditis elegans

Steven J. M. Jones, Martin Hirst, Stephane Flibotte, 2010, Genetics.

Products of the unc-52 gene in Caenorhabditis elegans are homologous to the core protein of the mammalian basement membrane heparan sulfate proteoglycan.

D. Moerman, T. Rogalski, B. D. Williams, 1993, Genes & development.

Complex patterns of alternative splicing mediate the spatial and temporal distribution of perlecan/UNC-52 in Caenorhabditis elegans.

D. Moerman, J. Bush, T. Rogalski, 1999, Molecular biology of the cell.

Chromosome Movements Promoted by the Mitochondrial Protein SPD-3 Are Required for Homology Search during Caenorhabditis elegans Meiosis

D. Moerman, A. Villeneuve, S. Flibotte, 2013, PLoS genetics.

Identification of ciliary and ciliopathy genes in Caenorhabditis elegans through comparative genomics

L. Stein, D. Moerman, M. Marra, 2006, Genome Biology.

Efficient high-resolution deletion discovery in Caenorhabditis elegans by array comparative genomic hybridization.

D. Moerman, T. Richmond, S. Flibotte, 2007, Genome research.

C. elegans deletion mutant screening.

D. Moerman, R. Barstead, 2006, Methods in molecular biology.

Sarcomeres pattern the proprioceptive sensory dendritic endings through Perlecan/UNC-52 in C. elegans

D. Moerman, K. Shen, Xing Liang, 2016 .

New Tools for Investigating the Comparative Biology of C. briggsae and C. elegans

R. Waterston, D. Moerman, J. Murray, 2009 .

Oligonucleotide Array Comparative Genomic Hybridization (oaCGH) based characterization of genetic deficiencies as an aid to gene mapping in Caenorhabditis elegans

D. Moerman, S. Flibotte, D. Baillie, 2007, BMC Genomics.

ELT-2 is the predominant transcription factor controlling differentiation and function of the C. elegans intestine, from embryo to adult.

Steven J. M. Jones, D. Moerman, M. Marra, 2009, Developmental biology.

The ELT-2 GATA-factor and the global regulation of transcription in the C. elegans intestine.

Steven J. M. Jones, Monica C. Sleumer, D. Moerman, 2007, Developmental biology.

C. elegans ADAMTS ADT-2 regulates body size by modulating TGFβ signaling and cuticle collagen organization.

D. Moerman, S. Flibotte, A. Meléndez, 2011, Developmental biology.

PhenoMIP: High-Throughput Phenotyping of Diverse Caenorhabditis elegans Populations via Molecular Inversion Probes

R. Waterston, D. Moerman, M. Edgley, 2020, G3.

PhenoMIP: High Throughput Phenotyping of Diverse C. elegans Populations via Molecular Inversion Probes

R. Waterston, D. Moerman, M. Edgley, 2019, bioRxiv.

Random and targeted transgene insertion in C. elegans using a modified Mosl transposon

D. Moerman, M. Davis, E. Jorgensen, 2014, Nature Methods.

DIM-1, a novel immunoglobulin superfamily protein in Caenorhabditis elegans, is necessary for maintaining bodywall muscle integrity.

D. Moerman, T. Rogalski, D. Devenport, 2003, Genetics.

Mutations in the unc-52 gene responsible for body wall muscle defects in adult Caenorhabditis elegans are located in alternatively spliced exons.

D. Moerman, T. Rogalski, G. P. Mullen, 1995, Genetics.

DNA Synthesis Generates Terminal Duplications That Seal End-to-End Chromosome Fusions

D. Moerman, S. Flibotte, Shawn Ahmed, 2011, Science.

Chromoanasynthetic Genomic Rearrangement Identified in a N-Ethyl-N-Nitrosourea (ENU) Mutagenesis Screen in Caenorhabditis elegans

D. Moerman, S. Flibotte, O. Itani, 2015, G3: Genes, Genomes, Genetics.

CRISPR-Cas9 human gene replacement and phenomic characterization in Caenorhabditis elegans to understand the functional conservation of human genes and decipher variants of uncertain significance

D. Moerman, C. Rankin, T. A. McDiarmid, 2018, Disease Models & Mechanisms.

The C. elegans UNC-23 protein, a member of the BCL-2-associated athanogene (BAG) family of chaperone regulators, interacts with HSP-1 to regulate cell attachment and maintain hypodermal integrity

D. Moerman, T. Rogalski, Poupak Rahmani, 2015, Worm.

Sequence of an unusually large protein implicated in regulation of myosin activity in C. elegans

R. Waterston, D. Moerman, G. Benian, 1989, Nature.

The mec-8 gene of C. elegans encodes a protein with two RNA recognition motifs and regulates alternative splicing of unc-52 transcripts.

D. Moerman, T. Rogalski, R. K. Herman, 1996, Development.

An Integrated Strategy to Study Muscle Development and Myofilament Structure in Caenorhabditis elegans

Steven J. M. Jones, D. Moerman, B. Meissner, 2009, PLoS genetics.

The C. elegans CDK8 Mediator module regulates axon guidance decisions in the ventral nerve cord and during dorsal axon navigation.

H. Hutter, D. Moerman, R. Zapf, 2013, Developmental biology.

Rapid High Resolution Single Nucleotide Polymorphism–Comparative Genome Hybridization Mapping in Caenorhabditis elegans

R. Waterston, D. Moerman, S. Flibotte, 2009, Genetics.

Transcriptome analysis for Caenorhabditis elegans based on novel expressed sequence tags

Steven J. M. Jones, E. Mardis, D. Moerman, 2008, BMC Biology.

The Caenorhabditis elegans paxillin orthologue, PXL-1, is required for pharyngeal muscle contraction and for viability

D. Moerman, A. Warner, H. Qadota, 2011, Molecular biology of the cell.

C . elegans UNC-98 , a C 2 H 2 Zn finger protein , is a novel partner of UNC-97 / PINCH in muscle adhesion complexes

D. Moerman, H. Qadota, D. Flaherty, 2003 .

Large-Scale Screening for Targeted Knockouts in the Caenorhabditis elegans Genome

D. Moerman, 2012, G3: Genes | Genomes | Genetics.

A Strategy To Isolate Modifiers of Caenorhabditis elegans Lethal Mutations: Investigating the Endoderm Specifying Ability of the Intestinal Differentiation GATA Factor ELT-2

D. Moerman, J. Duanmu, S. Flibotte, 2018, G3: Genes, Genomes, Genetics.

Production of antisense RNA leads to effective and specific inhibition of gene expression in C. elegans muscle.

A. Fire, D. Moerman, D. Albertson, 1991, Development.

CPNA-1, a copine domain protein, is located at integrin adhesion sites and is required for myofilament stability in Caenorhabditis elegans

D. Moerman, T. Rogalski, A. Warner, 2013, Molecular biology of the cell.

Formaldehyde mutagenesis in the nematode Caenorhabditis elegans.

D. Moerman, D. Baillie, D G Moerman, 1981, Mutation research.

Genetic Organization in CAENORHABDITIS ELEGANS: Fine-Structure Analysis of the unc-22 Gene.

D. Moerman, D. Baillie, 1979, Genetics.

Mitochondrial Mutation Rate, Spectrum and Heteroplasmy in Caenorhabditis elegans Spontaneous Mutation Accumulation Lines of Differing Population Size

R. Waterston, D. Moerman, P. Keightley, 2017, Molecular biology and evolution.

New Tools for Investigating the Comparative Biology of Caenorhabditis briggsae and C. elegans

R. Waterston, D. Moerman, J. Murray, 2010, Genetics.

Copy number variation in the genomes of twelve natural isolates of Caenorhabditis elegans

Stephane Flibotte, D. Moerman, S. Flibotte, 2010, BMC Genomics.

Unexpected Role for Dosage Compensation in the Control of Dauer Arrest, Insulin-Like Signaling, and FoxO Transcription Factor Activity in Caenorhabditis elegans

D. Moerman, S. Flibotte, G. Csankovszki, 2013, Genetics.

Accelerating Gene Discovery by Phenotyping Whole-Genome Sequenced Multi-mutation Strains and Using the Sequence Kernel Association Test (SKAT)

D. Moerman, S. Flibotte, S. Rademakers, 2015, bioRxiv.

Identification and analysis of internal promoters in Caenorhabditis elegans operons.

Steven J. M. Jones, D. Moerman, E. Pleasance, 2007, Genome research.

Caenorhabditis Identification and analysis of internal promoters in

D. Moerman, E. Pleasance, M. Marra, 2007 .

John Sulston (1942–2018): a personal perspective

R. Waterston, D. Moerman, 2020, Journal of neurogenetics.

Functional Genomics of the Cilium, a Sensory Organelle

Keith A. Boroevich, D. Moerman, M. Marra, 2005, Current Biology.

Characterization of the astacin family of metalloproteases in C. elegans

H. Hutter, D. Moerman, R. Zapf, 2010, BMC Developmental Biology.

Caenorhabditis elegans UNC-98, a C2H2 Zn finger protein, is a novel partner of UNC-97/PINCH in muscle adhesion complexes.

D. Moerman, H. Qadota, D. Flaherty, 2003, Molecular biology of the cell.

UNC-97 / PINCH in muscle adhesion complexes

D. Moerman, H. Qadota, D. Flaherty, 2003 .

Essential genes and deficiencies in the unc-22 IV region of Caenorhabditis elegans.

D. Moerman, D. Baillie, T. Rogalski, 1982, Genetics.

Mutations in the unc-54 myosin heavy chain gene of caenorhabditis elegans that alter contractility but not muscle structure

R. Waterston, D. Moerman, D. Baillie, 1982, Cell.

UBR-5, a conserved HECT-Type E3 ubiquitin ligase, negatively regulates notch-type signaling in Caenorhabditis elegans

D. Moerman, S. Flibotte, V. Au, 2019 .

Identification of a nematode chemosensory gene family.

Zeynep F. Altun, Lincoln D Stein, Shraddha Pai, 2005, Proceedings of the National Academy of Sciences of the United States of America.

The meiotic phosphatase GSP-2/PP1 promotes germline immortality and small RNA-mediated genome silencing

D. Moerman, S. Flibotte, P. Sarkies, 2019, PLoS genetics.

Mutational and transcriptional landscape of spontaneous gene duplications and deletions in Caenorhabditis elegans

R. Waterston, D. Moerman, S. Flibotte, 2018, Proceedings of the National Academy of Sciences.

C. elegans PAT-4/ILK Functions as an Adaptor Protein within Integrin Adhesion Complexes

D. Moerman, H. Qadota, B. D. Williams, 2002, Current Biology.

Identification of essential genes in Caenorhabditis elegans through whole-genome sequencing of legacy mutant collections

R. Schnabel, D. Moerman, S. Flibotte, 2021, G3.

Identification of essential genes in Caenorhabditis elegans through whole genome sequencing of legacy mutant collections

R. Schnabel, D. Moerman, S. Flibotte, 2021, bioRxiv.

A Conserved LIM Protein That Affects Muscular Adherens Junction Integrity and Mechanosensory Function in Caenorhabditis elegans

Gary Ruvkun, Oliver Hobert, Mary C. Beckerle, 1999, The Journal of cell biology.

Experimental analysis of oligonucleotide microarray design criteria to detect deletions by comparative genomic hybridization

Stephane Flibotte, D. Moerman, S. Flibotte, 2008 .

The UNC-112 Gene in Caenorhabditis elegansEncodes a Novel Component of Cell–Matrix Adhesion Structures Required for Integrin Localization in the Muscle Cell Membrane

D. Moerman, T. Rogalski, B. D. Williams, 2000, The Journal of cell biology.

Mutations in the sup-38 gene of Caenorhabditis elegans suppress muscle-attachment defects in unc-52 mutants.

D. Moerman, E. Gilchrist, 1992, Genetics.

α spectrin is essential for morphogenesis and body wall muscle formation in Caenorhabditis elegans

D. Moerman, Kenneth R Norman, K. Norman, 2002, The Journal of cell biology.

A Network of HSPG Core Proteins and HS Modifying Enzymes Regulates Netrin-Dependent Guidance of D-Type Motor Neurons in Caenorhabditis elegans

D. Moerman, S. Flibotte, M. Hengartner, 2013, PloS one.

Muscle: Structure, Function, and Development

Andrew Fire, A. Fire, D. Moerman, 1997 .

16 Muscle: Structure, Function, and Development

Andrew Fire, A. Fire, D. Moerman, 1997 .

A Molecular Mechanism for the Requirement of PAT-4 (Integrin-linked Kinase (ILK)) for the Localization of UNC-112 (Kindlin) to Integrin Adhesion Sites*

D. Moerman, H. Qadota, G. Benian, 2012, The Journal of Biological Chemistry.

UNC-97/PINCH is involved in the assembly of integrin cell adhesion complexes in Caenorhabditis elegans body wall muscle.

D. Moerman, H. Qadota, Kenneth R Norman, 2007, Developmental biology.

Identification of a novel Cdc42 GEF that is localized to the PAT-3-mediated adhesive structure.

D. Moerman, K. Kaibuchi, H. Qadota, 2005, Biochemical and biophysical research communications.

eEF2K inhibition blocks Aβ42 neurotoxicity by promoting an NRF2 antioxidant response

D. Moerman, M. Hayden, I. Mackenzie, 2016, Acta Neuropathologica.

Identifying novel genes in C. elegans using SAGE tags

Matthew J. Nesbitt, D. Moerman, Nansheng Chen, 2010, BMC Molecular Biology.

The let-268 locus of Caenorhabditis elegans encodes a procollagen lysyl hydroxylase that is essential for type IV collagen secretion.

D. Moerman, Kenneth R Norman, K. Norman, 2000, Developmental biology.

Spectrum of variations in dog-1/FANCJ and mdf-1/MAD1 defective Caenorhabditis elegans strains after long-term propagation

D. Moerman, S. Flibotte, Nansheng Chen, 2015, BMC Genomics.

Cyclin B3 and dynein heavy chain cooperate to increase fitness in the absence of mdf-1/MAD1 in Caenorhabditis elegans

D. Moerman, S. Flibotte, Nansheng Chen, 2014, Cell cycle.

Interstrain crosses enhance excision of Tc1 transposable elements in Caenorhabditis elegans

R. Waterston, D. Moerman, I. Mori, 2004, Molecular and General Genetics MGG.

Rapid Increase in frequency of gene copy-number variants during experimental evolution in Caenorhabditis elegans

Kendra J. Lipinski, D. Moerman, S. Flibotte, 2015, BMC Genomics.

Towards a mutation in every gene in Caenorhabditis elegans.

D. Moerman, R. Barstead, Donald G Moerman, 2008, Briefings in functional genomics & proteomics.

, by array comparative genomic hybridizationelegans CaenorhabditisEfficient high-resolution deletion discovery in data

D. Moerman, T. Richmond, S. Flibotte, 2007 .

Sarcomere assembly in C. elegans muscle.

D. Moerman, B. D. Williams, Donald G Moerman, 2006, WormBook : the online review of C. elegans biology.

Membrane extensions are associated with proper anterior migration of muscle cells during Caenorhabditis elegans embryogenesis.

H. Hutter, D. Moerman, R. Viveiros, 2011, Developmental biology.

Improved detection of small deletions in complex pools of DNA.

D. Moerman, G. Moulder, R. Barstead, 2002, Nucleic acids research.

UNC-52/perlecan isoform diversity and function in Caenorhabditis elegans.

D. Moerman, J. Bush, T. Rogalski, 2001, Biochemical Society transactions.

Establishment of a tissue-specific RNAi system in C. elegans.

D. Moerman, K. Kaibuchi, M. Amano, 2007, Gene.

Cell autonomous expression of perlecan and plasticity of cell shape in embryonic muscle of Caenorhabditis elegans.

R. Schnabel, H. Hutter, D. Moerman, 1996, Developmental biology.

CRISPR/Cas9 Methodology for the Generation of Knockout Deletions in Caenorhabditis elegans

A. Rougvie, H. Hutter, D. Moerman, 2018, G3: Genes, Genomes, Genetics.

The Molecular Chaperone HSP90 Promotes Notch Signaling in the Germline of Caenorhabditis elegans

D. Moerman, Y. Liu, S. Flibotte, 2018, G3: Genes, Genomes, Genetics.

C. elegans PAT-6/Actopaxin Plays a Critical Role in the Assembly of Integrin Adhesion Complexes In Vivo

D. Moerman, H. Qadota, B. D. Williams, 2003, Current Biology.

Gap junctions in C. elegans

Christian C. Naus, D. Moerman, C. Naus, 2014, Front. Physiol..

Targeted gene deletions in C. elegans using transposon excision

Erik M. Jorgensen, Christian Frøkjær-Jensen, Paola Nix, 2010, Nature Methods.

The conserved phosphatase GSP-2/PP1 promotes germline immortality via small RNA-mediated genome silencing during meiosis

D. Moerman, S. Flibotte, P. Sarkies, 2018, bioRxiv.

MIP-MAP: High-Throughput Mapping of Caenorhabditis elegans Temperature-Sensitive Mutants via Molecular Inversion Probes

R. Waterston, R. Schnabel, D. Moerman, 2017, Genetics.

CPNA-1, a Copine Domain Protein, Is Located at Integrin Adhesion Sites, and Is Required for Myofilament Stability in C. elegans (P07.037)

D. Moerman, T. Rogalski, A. Warner, 2013 .

Sarcomeres Pattern Proprioceptive Sensory Dendritic Endings through UNC-52/Perlecan in C. elegans.

D. Moerman, K. Shen, Xing Liang, 2015, Developmental cell.

by array comparative genomic hybridization elegans Caenorhabditis Efficient high-resolution deletion discovery in

D. Moerman, T. Richmond, S. Flibotte, 2007 .

Rapid Increase in frequency of gene copy-number variants during experimental evolution in Caenorhabditis elegans

Kendra J. Lipinski, D. Moerman, S. Flibotte, 2015, BMC Genomics.

UBR-5, a Conserved HECT-Type E3 Ubiquitin Ligase, Negatively Regulates Notch-Type Signaling in Caenorhabditis elegans

D. Moerman, S. Flibotte, V. Au, 2016, G3: Genes, Genomes, Genetics.

Big Data in Caenorhabditis elegans: quo vadis?

H. Hutter, D. Moerman, 2015, Molecular biology of the cell.

MIP-MAP: High Throughput Mapping of Caenorhabditis elegans Temperature Sensitive Mutants via Molecular Inversion Probes

R. Waterston, R. Schnabel, D. Moerman, 2017, bioRxiv.

Spectrum of variations in dog-1/FANCJ and mdf-1/MAD1 defective Caenorhabditis elegans strains after long-term propagation

D. Moerman, S. Flibotte, Nansheng Chen, 2015, BMC Genomics.

Cis-regulatory Mutations in the Caenorhabditis elegans Homeobox Gene Locus cog-1 Affect Neuronal Development

D. Moerman, O. Hobert, S. Flibotte, 2009, Genetics.

Cis-regulatory mutations in the C . elegans homeobox gene locus cog-1 affect neuronal development

D. Moerman, O. Hobert, S. Flibotte, 2009 .

Molecular cloning of the muscle gene unc-22 in Caenorhabditis elegans by Tc1 transposon tagging.

R. Waterston, D. Moerman, G. Benian, 1986, Proceedings of the National Academy of Sciences of the United States of America.

Organ morphogenesis: A metalloprotease prepares the way

D. Moerman, 1999, Current Biology.

Peel-1 negative selection promotes screening-free CRISPR-Cas9 genome editing in Caenorhabditis elegans

D. Moerman, C. Rankin, T. McDiarmid, 2020, bioRxiv.

De Novo Identification of Single Nucleotide Mutations in Caenorhabditis elegans Using Array Comparative Genomic Hybridization

D. Moerman, S. Flibotte, H. M. Okada, 2009, Genetics.

Transcriptome analysis for Caenorhabditis elegansbased on novel expressed sequence tags

E. Mardis, D. Moerman, M. Marra, 2008, BMC Biology.

Genetic Control of Vulval Development in Caenorhabditis briggsae

R. Waterston, D. Moerman, S. Flibotte, 2012, G3: Genes | Genomes | Genetics.

De novo identification of single nucleotide mutations in C . elegans using array Comparative Genomic Hybridization

D. Moerman, S. Flibotte, H. M. Okada, 2009 .

The ELT-2 GATA-factor and the global regulation of transcription in the C. elegans intestine.

Monica C. Sleumer, D. Moerman, Kim Wong, 2007, Developmental biology.

Analysis of a mutator activity necessary for germline transposition and excision of Tc1 transposable elements in Caenorhabditis elegans.

R. Waterston, D. Moerman, I. Mori, 1988, Genetics.

Cis-regulatory Mutations in the Caenorhabditis elegans Homeobox Gene Locus cog-1 Affect Neuronal Development

D. Moerman, M. O'Meara, S. Flibotte, 2009, Genetics.

Identification and analysis of internal promoters in Caenorhabditis elegans operons.

D. Moerman, E. Pleasance, M. Marra, 2007, Genome research.

Genetic fine structure analysis of the myosin heavy chain gene unc-54 of Caenorhabditis elegans.

R. Waterston, D. Moerman, K. C. Smith, 1982, Journal of molecular biology.

α spectrin is essential for morphogenesis and body wall muscle formation in Caenorhabditis elegans

D. Moerman, Kenneth R Norman, 2002, The Journal of cell biology.

Optimizing guide RNA selection and CRISPR/Cas9 methodology for efficient generation of deletions in C. elegans

A. Rougvie, H. Hutter, D. Moerman, 2018, bioRxiv.

Germline excision of the transposable element Tc1 in C. elegans.

D. Moerman, R H Waterston, Jane E. Kiff, 1991, Nucleic acids research.