S. Sprang

发表

Structural basis for the activation of glycogen phosphorylase b by adenosine monophosphate.

S. Sprang, S. Withers, E. Goldsmith, 1991, Science.

Structure of the first C2 domain of synaptotagmin I: A novel Ca2+/phospholipid-binding fold

S. Sprang, A. Berghuis, R. Sutton, 1995, Cell.

The structure of the G protein heterotrimer Gi alpha 1 beta 1 gamma 2.

S. Sprang, A. Gilman, M. Wall, 1995, Cell.

The structure of the G protein heterotrimer Giα1 β 1 γ 2

S. Sprang, A. Gilman, M. Wall, 1995, Cell.

The structure of tumor necrosis factor-alpha at 2.6 A resolution. Implications for receptor binding.

S. Sprang, M. Eck, 1990, The Journal of biological chemistry.

The structure of human lymphotoxin (tumor necrosis factor-beta) at 1.9-A resolution.

S R Sprang, S. Sprang, M. Ultsch, 1992, The Journal of biological chemistry.

Three-Dimensional Structure of a Complex between the Death Domains of Pelle and Tube

S. Sprang, S. Wasserman, T. Xiao, 1999, Cell.

Crystallization of trimeric recombinant human tumor necrosis factor (cachectin).

S. Sprang, B. Beutler, M. Eck, 1988, The Journal of biological chemistry.

A Specific Interaction of Small Molecule Entry Inhibitors with the Envelope Glycoprotein Complex of the Junín Hemorrhagic Fever Arenavirus*

S. Sprang, D. Boger, D. Decamp, 2010, The Journal of Biological Chemistry.

Structure of RGS4 Bound to AlF4 −-Activated Giα1: Stabilization of the Transition State for GTP Hydrolysis

S. Sprang, A. Gilman, J. Tesmer, 1997, Cell.

G proteins, effectors and GAPs: structure and mechanism.

S R Sprang, S. Sprang, 1997, Current opinion in structural biology.

Crystal and cryo-EM structures of the cytosolic G protein alpha chaperone and guanine nucleotide exchange factor Ric-8A bound to Gαi1

S. Sprang, W. Chiu, J. Steyaert, 2020, bioRxiv.

Structure of the G protein chaperone and guanine nucleotide exchange factor Ric-8A bound to Gαi1

S. Sprang, W. Chiu, J. Steyaert, 2020, Nature Communications.

Ric-8A, a G protein chaperone with nucleotide exchange activity induces long-range secondary structure changes in Gα

S. Sprang, R. Kant, Celestine J. Thomas, 2016, eLife.

Invited review: Activation of G proteins by GTP and the mechanism of Gα‐catalyzed GTP hydrolysis

S. Sprang, 2016, Biopolymers.

C2 domains from different Ca2+ signaling pathways display functional and mechanistic diversity.

S. Sprang, K. Mikoshiba, J. Falke, 2001, Biochemistry.

Two crystal forms of the extracellular domain of type I tumor necrosis factor receptor.

S. Sprang, L. Rodseth, J. Naismith, 1994, Journal of molecular biology.

Cosolvent-induced transformation of a death domain tertiary structure

S. Sprang, K. Gardner, T. Xiao, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Structure of the rgRGS domain of p115RhoGEF

S. Sprang, C. Wells, P. Sternweis, 2001, Nature Structural Biology.

Kinetic isotope effects in Ras-catalyzed GTP hydrolysis: Evidence for a loose transition state

S. Sprang, Xinlin Du, P. Lecchi, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Transition state structures and the roles of catalytic residues in GAP-facilitated GTPase of Ras as elucidated by (18)O kinetic isotope effects.

S. Sprang, Xinlin Du, 2009, Biochemistry.

The divergent receptors for TNF.

S. Sprang, 1990, Trends in biochemical sciences.

Structure, Function, and Dynamics of the Gα Binding Domain of Ric-8A.

S. Sprang, T. Mou, G. Tall, 2019, Structure.

Tumor necrosis factor receptor superfamily.

S. Sprang, J. Naismith, 1995, Journal of inflammation.

Mechanism of GTP hydrolysis by G-protein alpha subunits.

S. Sprang, A. Gilman, E. Lee, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Structural biology: A receptor unlocked

S. Sprang, 2007, Nature.

Crystallization of the gene 45 protein from the DNA replication fork of bacteriophage T4.

B. Alberts, C. Thaller, S. Sprang, 1984, The Journal of biological chemistry.

GEFs: master regulators of G-protein activation.

S. Sprang, 2001, Trends in biochemical sciences.

Differential interactions of the catalytic subunits of adenylyl cyclase with forskolin analogs.

S. Sprang, R. Seifert, Cibele S. Pinto, 2009, Biochemical pharmacology.

Crystallization of complex between soluble domains of adenylyl cyclase and activated Gs alpha.

S. Sprang, R. Sunahara, A. Gilman, 2002, Methods in enzymology.

Structural and Biochemical Characterization of the GTP γ S-, GDP ‚ Pi-, and GDP-Bound Forms of a GTPase-Deficient Gly 42 f Val Mutant of Gi R 1 †

S. Sprang, A. Gilman, D. Coleman, 1997 .

Structure of a mitochondrial cytochrome c conformer competent for peroxidase activity

S. Sprang, B. Bowler, T. Mou, 2014, Proceedings of the National Academy of Sciences.

Contribution of E.S.R. analysis toward diagenic mechanisms in bituminous deposits

S. Sprang, T. Yen, 1977 .

The three-dimensional structure of Asn102 mutant of trypsin: role of Asp102 in serine protease catalysis.

R M Stroud, R J Fletterick, W. Rutter, 1988, Science.

Catalytic site of glycogen phosphorylase: structure of the T state and specificity for alpha-D-glucose.

R J Fletterick, S R Sprang, S. Sprang, 1982, Biochemistry.

Modeling the biochemical differences between rabbit muscle and human liver phosphorylase

R J Fletterick, S R Sprang, S. Sprang, 1987, Proteins.

Catalytic site of glycogen phosphorylase: structural changes during activation and mechanistic implications.

S. Sprang, S. Withers, R. Fletterick, 1982, Biochemistry.

Analysis of the surface topography of glycogen phosphorylase a: implications for metabolic interconversion and regulatory mechanisms.

S. Sprang, R. Fletterick, N. Madsen, 1979, Canadian journal of biochemistry.

Structural and biochemical characterization of the GTPgammaS-, GDP.Pi-, and GDP-bound forms of a GTPase-deficient Gly42 --> Val mutant of Gialpha1.

S. Sprang, A. Gilman, D. Coleman, 1997, Biochemistry.

Tertiary and quaternary structural changes in Gi alpha 1 induced by GTP hydrolysis.

S. Sprang, A. Gilman, A. Berghuis, 1995, Science.

The Nucleotide Exchange Factor Ric-8A Is a Chaperone for the Conformationally Dynamic Nucleotide-Free State of Gαi1

S. Sprang, J. Sumida, J. Hilmer, 2011, PloS one.

Structures of active conformations of Gi alpha 1 and the mechanism of GTP hydrolysis.

S. Sprang, A. Gilman, A. Berghuis, 1994, Science.

Broad Specificity of Mammalian Adenylyl Cyclase for Interaction with 2′,3′-Substituted Purine- and Pyrimidine Nucleotide Inhibitors

Roland Seifert, Andreas Gille, S. Sprang, 2006, Molecular Pharmacology.

Structural Basis for the Inhibition of Mammalian Membrane Adenylyl Cyclase by 2 ′(3′)-O-(N-Methylanthraniloyl)-guanosine 5 ′-Triphosphate*

Roland Seifert, Andreas Gille, S. Sprang, 2005, Journal of Biological Chemistry.

Multiple phosphate positions in the catalytic site of glycogen phosphorylase: Structure of the pyridoxal‐5′‐pyrophosphate coenzyme‐substrate analog

S. Sprang, S. Withers, N. Madsen, 1992, Protein science : a publication of the Protein Society.

The crystal structure and conformation of 2',3'‐O‐isopropylideneadenosine: the co‐existence of a planar and a puckered ribofuranose ring

S. Sprang, M. Sundaralingam, D. Rohrer, 1978 .

Structural changes in glycogen phosphorylase induced by phosphorylation

S. Sprang, E. Goldsmith, R. Fletterick, 1988, Nature.

Analysis of an allosteric binding site: the nucleoside inhibitor site of phosphorylase alpha.

S. Sprang, R. Fletterick, N. Madsen, 1982, Biochemistry.

Catalytic Mechanism of Mammalian Adenylyl Cyclase: A Computational Investigation.

S. Sprang, D. K. Hahn, X. Chu, 2015, Biochemistry.

Three-dimensional structure of human basic fibroblast growth factor, a structural homolog of interleukin 1β

S. Sprang, P. Barr, L. Cousens, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Three-dimensional structure of human basic fibroblast growth factor, a structural homolog of interleukin 1 beta.

S. Sprang, P. Barr, L. Cousens, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Molecular chaperoning function of Ric-8 is to fold nascent heterotrimeric G protein α subunits

S. Sprang, G. Tall, Pui-Yee Chan, 2013, Proceedings of the National Academy of Sciences.

G protein mechanisms: insights from structural analysis.

S R Sprang, S. Sprang, 1997, Annual review of biochemistry.

Crystal structure of the catalytic domains of adenylyl cyclase in a complex with Gsalpha.GTPgammaS.

S R Sprang, S. Sprang, R. Sunahara, 1997 .

Three-Dimensional Structure of a Complex between the Death Domains of Pelle and Tube The amino-terminal interaction modules of Pelle and Tube show limited amino acid sequence similarity to death domains , a family of folds identified in proteins

S. Sprang, S. Wasserman, T. Xiao, 1999 .

Solvent accessibility properties of complex proteins

S. Sprang, R. Fletterick, D. Yang, 1979, Nature.

Crystal structure of the major quadruplex formed in the promoter region of the human c-MYC oncogene

S. Sprang, T. Mou, H. Beall, 2018, PloS one.

Affinity panning of a library of peptides displayed on bacteriophages reveals the binding specificity of BiP

S. Sprang, J. Sambrook, M. Gething, 1993, Cell.

Cytokine structural taxonomy and mechanisms of receptor engagement

S. Sprang, J. Bazan, Stephen R. Sprang, 1993 .

Structural Basis for Negative Allosteric Modulation of GluN2A-Containing NMDA Receptors

S. Sprang, R. Volkmann, F. Menniti, 2016, Neuron.

Inhibitors of membranous adenylyl cyclases.

Roland Seifert, Andreas Gille, Gerald H Lushington, 2012, Trends in pharmacological sciences.

Structural and Molecular Characterization of a Preferred Protein Interaction Surface on G Protein βγ Subunits

S. Sprang, A. Smrcka, Tabetha M. Bonacci, 2005 .

Crystal structure of the adenylyl cyclase activator Gsalpha.

S. Sprang, R. Sunahara, A. Gilman, 1997, Science.

Interactive program for visualization and modelling of proteins, nucleic acids and small molecules

R J Fletterick, A Tramontano, H E Dayringer, 1986 .

Structures of the extracellular domain of the type I tumor necrosis factor receptor.

S R Sprang, S. Sprang, T. Kohno, 1996, Structure.

Tertiary and Quaternary Structural Changes in Giα1 Induced by GTP Hydrolysis

S. Sprang, A. Gilman, A. Berghuis, 1995, Science.

Structure of Giα1·GppNHp, Autoinhibition in a Gα Protein-Substrate Complex*

S. Sprang, D. Coleman, Stephen R. Sprang, 1999, The Journal of Biological Chemistry.

Structural basis of effector regulation and signal termination in heterotrimeric Galpha proteins.

S. Sprang, Xinlin Du, Zhe Chen, 2007, Advances in protein chemistry.

Conformational Display: A Role for Switch Polymorphism in the Superfamily of Regulatory GTPases

S. Sprang, 2000, Science's STKE.

GAP into the Breach

S. Sprang, 1997, Science.

proteins , effectors and GAPs : structure and mechanism

S. Sprang, 1997 .

Structural basis for inhibition of mammalian adenylyl cyclase by calcium.

S. Sprang, D. Cooper, T. Mou, 2009, Biochemistry.

Seeing double: Crystal structures of the type I TNF receptor

S. Sprang, J. Naismith, B. Brandhuber, 1996, Journal of molecular recognition : JMR.

Invasion of the Nucleotide Snatchers Structural Insights into the Mechanism of G Protein GEFs

S. Sprang, D. Coleman, 1998, Cell.

Mapping the Gα13 Binding Interface of the rgRGS Domain of p115RhoGEF*

S. Sprang, C. Wells, P. Sternweis, 2003, The Journal of Biological Chemistry.

Biochemical Reconstitution of Hemorrhagic-Fever Arenavirus Envelope Glycoprotein-Mediated Membrane Fusion

S. Sprang, J. York, J. Nunberg, 2012, PloS one.

How G proteins work: a continuing story.

S. Sprang, D. Coleman, 1996, Trends in biochemical sciences.

The structure of the cysteine-rich region from human histone-lysine N-methyltransferase EHMT2 (G9a)

S. Sprang, T. Mou, K. M. Kerchner, 2021, Journal of structural biology: X.

Differential Inhibition of Various Adenylyl Cyclase Isoforms and Soluble Guanylyl Cyclase by 2′,3′-O-(2,4,6-Trinitrophenyl)-Substituted Nucleoside 5′-Triphosphates

S. Sprang, R. Seifert, T. Mou, 2009, Journal of Pharmacology and Experimental Therapeutics.

Structures, mechanism, regulation and evolution of class III nucleotidyl cyclases.

S. Sprang, S. Sinha, Sangita C. Sinha, 2006, Reviews of physiology, biochemistry and pharmacology.

Two-metal-Ion catalysis in adenylyl cyclase.

S R Sprang, S. Sprang, R. Sunahara, 1999, Science.

35 – Subunit Interactions and the Function of Tumor Necrosis Factor

S. Sprang, M. Eck, 1990 .

Structure of maltoheptaose by difference Fourier methods and a model for glycogen.

S. Sprang, E. Goldsmith, R. Fletterick, 1982, Journal of molecular biology.

Chapter 48 - Structure and Function of Tumor Necrosis Factor at the Cell Surface

S. Sprang, 2003 .

Atypical activation of the G protein Gαq by the oncogenic mutation Q209P

S. Sprang, Anthony Leyme, Marcin Maziarz, 2018, The Journal of Biological Chemistry.

Redesigning trypsin via genetic engineering

W. Rutter, S. Sprang, R. Fletterick, 1987, Journal of cellular biochemistry.

Modularity in the TNF-receptor family.

S R Sprang, S. Sprang, J. Naismith, 1998, Trends in biochemical sciences.

Intron–exon splice junctions map at protein surfaces

Robert Fletterick, William J. Rutter, Charles S. Craik, 1982, Nature.

Exchange of Substrate and Inhibitor Specificities between Adenylyl and Guanylyl Cyclases*

S. Sprang, R. Sunahara, A. Gilman, 1998, The Journal of Biological Chemistry.

Cytochrome c Can Form a Well-Defined Binding Pocket for Hydrocarbons.

S. Sprang, B. Bowler, T. Mou, 2016, Journal of the American Chemical Society.

THE RELATIONSHIP OF GENE STRUCTURE TO PROTEIN STRUCTURE

W. Rutter, S. Sprang, R. Fletterick, 1982 .

Molecular basis for P-site inhibition of adenylyl cyclase.

S R Sprang, S. Sprang, R. Sunahara, 2000, Biochemistry.

A Peptide Core Motif for Binding to Heterotrimeric G Protein α Subunits*

S. Sprang, R. Roberts, W. Ja, 2005, Journal of Biological Chemistry.

The interactions of adenylate cyclases with P-site inhibitors.

S. Sprang, C. Dessauer, A. Gilman, 1999, Trends in pharmacological sciences.

Identification of a Giα Binding Site on Type V Adenylyl Cyclase*

S. Sprang, C. Dessauer, A. Gilman, 1998, The Journal of Biological Chemistry.

Crystal structures of the G protein Gi alpha 1 complexed with GDP and Mg2+: a crystallographic titration experiment.

S. Sprang, D. Coleman, 1998, Biochemistry.

Ric-8A Catalyzes Guanine Nucleotide Exchange on Gαi1 Bound to the GPR/GoLoco Exchange Inhibitor AGS3*

S. Sprang, G. Tall, A. Adhikari, 2008, Journal of Biological Chemistry.

The structure, catalytic mechanism and regulation of adenylyl cyclase.

S. Sprang, J. Tesmer, 1998, Current opinion in structural biology.

Cell signalling: Binding the receptor at both ends

S. Sprang, Stephen R. Sprang, 2011, Nature.

Structure of the nucleotide activation switch in glycogen phosphorylase a.

S. Sprang, E. Goldsmith, R. Fletterick, 1987, Science.

Domain separation in the activation of glycogen phosphorylase a.

S. Sprang, E. Goldsmith, R. Fletterick, 1989, Science.

Studies of specificity and catalysis in trypsin by structural analysis of site-directed mutants.

W. Rutter, S. Sprang, R. Fletterick, 1988, Critical reviews in biotechnology.

Structures of Heterotrimeric G Proteins and Their Complexes

S. Sprang, 2010 .

CHAPTER 22 – Structures of Heterotrimeric G Proteins and Their Complexes

S. Sprang, 2003 .

Recognition of the activated states of Galpha13 by the rgRGS domain of PDZRhoGEF.

Shahab M. Danesh, S. Sprang, P. Sternweis, 2008, Structure.

Structure of the p115RhoGEF rgRGS domain–Gα13/i1 chimera complex suggests convergent evolution of a GTPase activator

S. Sprang, P. Sternweis, Zhe Chen, 2005, Nature Structural &Molecular Biology.

Uncoupling conformational change from GTP hydrolysis in a heterotrimeric G protein α-subunit

S. Sprang, E. Ross, Pilong Li, 2004 .

Structural basis of activity and subunit recognition in G protein heterotrimers.

S. Sprang, M. Wall, B. Posner, 1998, Structure.

Structural Origins of Receptor Bias

S. Sprang, Jackson Chief Elk, 2012, Science.

Studies of specificity and catalysis in trypsin by structural analysis of site-directed mutants

W. Rutter, S. Sprang, R. Fletterick, 1987 .

Crystallographic Evidence for Dimerization of Unliganded Tumor Necrosis Factor Receptor (*)

S R Sprang, S. Sprang, J. Naismith, 1995, The Journal of Biological Chemistry.

Modulation of a GEF switch: Autoinhibition of the intrinsic guanine nucleotide exchange activity of p115‐RhoGEF

S. Sprang, P. Sternweis, Liang Guo, 2011, Protein science : a publication of the Protein Society.

The structure of glycogen phosphorylase a at 2.5 Å resolution

S. Sprang, R. Fletterick, 1979 .

[4] Reaction dynamics of G-protein catalyzed hydrolysis of GTP as viewed by X-ray crystallographic snapshots of Giα1

S. Sprang, D. Coleman, 1999 .

Structure of the GDP–Pi complex of Gly203→Ala Giα1: a mimic of the ternary product complex of Gα-catalyzed GTP hydrolysis

S. Sprang, A. Gilman, A. Berghuis, 1996 .

Structure of the G protein chaperone and guanine nucleotide exchange factor Ric-8A bound to Gαi1

S. Sprang, W. Chiu, J. Steyaert, 2020, Nature Communications.

Nanosecond Dynamics of Gαi1 Bound to Nucleotides or Ric-8A, a Gα Chaperone with GEF Activity.

S. Sprang, J. Ross, L. Black, 2016, Biophysical journal.

Structure-activity relationships for the interactions of 2'- and 3'-(O)-(N-methyl)anthraniloyl-substituted purine and pyrimidine nucleotides with mammalian adenylyl cyclases.

S. Sprang, R. Seifert, Cibele S. Pinto, 2011, Biochemical pharmacology.

Structural Basis for the High-Affinity Inhibition of Mammalian Membranous Adenylyl Cyclase by 2′,3′-O-(N-Methylanthraniloyl)-Inosine 5′-Triphosphate

S. Sprang, A. Dixit, R. Seifert, 2011, Molecular Pharmacology.

Structure of Gialpha1.GppNHp, autoinhibition in a galpha protein-substrate complex.

S. Sprang, D. Coleman, 1999, The Journal of biological chemistry.

Glycogen phosphorylase structures and function

S. Sprang, R. Fletterick, 1982 .

Subunit interactions and the allosteric response in phosphorylase.

S. Sprang, R. Fletterick, 1980, Biophysical journal.

Uncoupling conformational change from GTP hydrolysis in a heterotrimeric G protein alpha-subunit.

S. Sprang, E. Ross, Pilong Li, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Structure of the GDP-Pi complex of Gly203-->Ala gialpha1: a mimic of the ternary product complex of galpha-catalyzed GTP hydrolysis.

S. Sprang, A. Gilman, A. Berghuis, 1996, Structure.

A Bull's Eye for Targeted Lung Cancer Therapy

S. Sprang, J. Minna, A. Gazdar, 2004, Science.

Cancer. A bull's eye for targeted lung cancer therapy.

S. Sprang, J. Minna, A. Gazdar, 2004, Science.

The latent tendencies of PAI-1.

S. Sprang, 1992, Trends in biochemical sciences.

Distinct Interactions of GTP, UTP, and CTP with GsProteins*

S. Sprang, Hui-yu Liu, R. Seifert, 2002, The Journal of Biological Chemistry.

A method to determine 18 O kinetic isotope effects in the hydrolysis of nucleotide triphosphates.

S. Sprang, Xinlin Du, R. Gregory, 2008, Analytical biochemistry.

Thermodynamic Characterization of the Binding of Activator of G Protein Signaling 3 (AGS3) and Peptides Derived from AGS3 with Gαi1*

S. Sprang, A. Adhikari, Anirban Adhikari, 2003, Journal of Biological Chemistry.

The A326S Mutant of Giα1 as an Approximation of the Receptor-bound State*

S. Sprang, A. Gilman, M. Wall, 1998, Journal of Biological Chemistry.

Activation of p115-RhoGEF Requires Direct Association of Gα13 and the Dbl Homology Domain*

S. Sprang, P. Sternweis, Liang Guo, 2012, The Journal of Biological Chemistry.

Activated RhoA Binds to the Pleckstrin Homology (PH) Domain of PDZ-RhoGEF, a Potential Site for Autoregulation*♦

Zhe Chen, S. Sprang, P. Sternweis, 2010, The Journal of Biological Chemistry.

Gia1: Stabilization of the Transition State for GTP Hydrolysis

S. Sprang, A. Gilman, J. Tesmer, 1997 .

Alternative binding modes for maltopentaose in the activation site of glycogen phosphorylase a

S. Sprang, E. Goldsmith, R. Fletterick, 1989 .

Structure of the protein kinase Cbeta phospholipid-binding C2 domain complexed with Ca2+.

S. Sprang, R B Sutton, 1998, Structure.

Conformational analysis of 8-azanucleosides. Crystal and molecular structure of 8-azatubercidin monohydrate, a nucleoside analog exhibiting the "high anti" conformation

S. Sprang, M. Sundaralingam, D. Rohrer, 1978 .

Faculty Opinions recommendation of NMR analysis of G-protein betagamma subunit complexes reveals a dynamic G(alpha)-Gbetagamma subunit interface and multiple protein recognition modes.

S. Sprang, 2010 .

Crystal structure of the catalytic domains of adenylyl cyclase in a complex with Gsalpha.GTPgammaS.

S. Sprang, R. Sunahara, A. Gilman, 1997, Science.

Origin of asymmetry in adenylyl cyclases: structures of Mycobacterium tuberculosis Rv1900c

S. Sprang, J. Schultz, S. Sinha, 2005, The EMBO journal.

How Ras works: structure of a Rap-Raf complex.

S. Sprang, 1995, Structure.

Crystal structure of the major quadruplex formed in the promoter region of the human c-MYC oncogene

S. Sprang, T. Mou, H. Beall, 2018, PloS one.

The guanine nucleotide exchange factor Ric-8A induces domain separation and Ras domain plasticity in Gαi1

S. Sprang, W. Hubbell, N. Van Eps, 2015, Proceedings of the National Academy of Sciences.

Structure of a rat α1‐macroglobulin receptor‐binding domain dimer

S. Sprang, D. Decamp, T. Xiao, 2000, Protein science : a publication of the Protein Society.

The crystallographic structure of a G protein heterotrimer

S. Sprang, A. Gilman, M. Wall, 1996 .

Cytochrome c Can Form a Well-Defined Binding Pocket for Hydrocarbons.

S. Sprang, B. Bowler, T. Mou, 2016, Journal of the American Chemical Society.

Differential Inhibition of Various Adenylyl Cyclase Isoforms and Soluble Guanylyl Cyclase by 2′,3′-O-(2,4,6-Trinitrophenyl)-Substituted Nucleoside 5′-Triphosphates

S. Sprang, R. Seifert, T. Mou, 2009, Journal of Pharmacology and Experimental Therapeutics.

Crystal structure of 2-chloro-1-(β-d-ribofuranosyl)benzimidazole. Hydrogen bonding to the furanose ring oxygen

S. Sprang, M. Sundaralingam, 1973 .

Crystallization and preliminary crystallographic studies of Giα1 and mutants of Giα1 in the GTP and GDP-bound states

S. Sprang, A. Gilman, A. Berghuis, 1994 .

References and Notes Materials and Methods Figs. S1 to S6 Tables S1 and S2 References Computational Constraints on Syntactic Processing in a Nonhuman Primate

W. Fitch, M. Hauser, S. Sprang, 2022 .

Heterotrimeric G Proteins

S. Sprang, D. Decamp, 2014 .

Structural and molecular characterization of a preferred protein interaction surface on G protein beta gamma subunits.

S. Sprang, A. Smrcka, Tabetha M. Bonacci, 2005, Biochemistry.