B. Walker

Victor DeGruttola, Kaveh Maghsoudi, Nesli Basgoz, 2006, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

A Subset of Latency-Reversing Agents Expose HIV-Infected Resting CD4+ T-Cells to Recognition by Cytotoxic T-Lymphocytes

D. Irvine, B. Walker, A. Trocha, 2016, PLoS pathogens.

HIV-specific CD8⁺ T cells and HIV eradication.

R. Siliciano, B. Walker, R. B. Jones, 2016, The Journal of clinical investigation.

A Subset of Latency-Reversing Agents Expose HIV-Infected Resting CD 4 T-Cells to Recognition by Cytotoxic T-Lymphocytes Citation

Darrell, B. Walker, A. Trocha, 2016 .

IL-10 is up-regulated in multiple cell types during viremic HIV infection and reversibly inhibits virus-specific T cells.

H. Jessen, F. Pereyra, B. Walker, 2009, Blood.

HIV-1 superinfection despite broad CD8+ T-cell responses containing replication of the primary virus

Todd M. Allen, E. Rosenberg, M. Altfeld, 2002, Nature.

HIV-1 superinfection--a word of caution.

B. Walker, P. Goulder, 2002, The New England journal of medicine.

Factors Predicting Discordant Virological and Immunological Responses to Antiretroviral Therapy in HIV-1 Clade C Infected Zulu/Xhosa in South Africa

M. Altfeld, B. Walker, B. Julg, 2012, PloS one.

Role of HIV-specific CD8+ T cells in pediatric HIV cure strategies after widespread early viral escape

B. Walker, O. Pybus, T. Ndung’u, 2017, The Journal of experimental medicine.

Reconstitution of Virus-Specific CD4 Proliferative Responses in Pediatric HIV-1 Infection 1

B. Walker, M. Feeney, P. Goulder, 2003, The Journal of Immunology.

Comprehensive Screening Reveals Strong and Broadly Directed Human Immunodeficiency Virus Type 1-Specific CD8 Responses in Perinatally Infected Children

B. Walker, M. Feeney, P. Goulder, 2003, Journal of Virology.

HLA class I-restricted cytotoxic T lymphocytes specific for hepatitis C virus. Identification of multiple epitopes and characterization of patterns of cytokine release.

B. Walker, C. Rice, M. Houghton, 1995, The Journal of clinical investigation.

Selection, Transmission, and Reversion of an Antigen-Processing Cytotoxic T-Lymphocyte Escape Mutation in Human Immunodeficiency Virus Type 1 Infection

Alessandro Sette, Kenneth A. Freedberg, Philip J. R. Goulder, 2004, Journal of Virology.

Early virological suppression with three-class antiretroviral therapy in HIV-infected African infants

B. Walker, W. Mphatswe, P. Goulder, 2008, AIDS.

HIV-1 Antiviral Activity of Recombinant Natural Killer Cell Enhancing Factors, NKEF-A and NKEF-B, Members of the Peroxiredoxin Family*

J. Lieberman, B. Walker, M. Addo, 2003, The Journal of Biological Chemistry.

Impaired Hepatitis C Virus-Specific T Cell Responses and Recurrent Hepatitis C Virus in HIV Coinfection

Todd M. Allen, B. Walker, G. Lauer, 2006, PLoS medicine.

Comparison of overlapping peptide sets for detection of antiviral CD8 and CD4 T cell responses.

M. Altfeld, B. Walker, C. Brander, 2003, Journal of immunological methods.

Sustained Dysfunction of Antiviral CD8+ T Lymphocytes after Infection with Hepatitis C Virus

B. Walker, P. Klenerman, G. Lauer, 2001, Journal of Virology.

Immunopathogenesis and immunotherapy in AIDS virus infections

B. Walker, N. Letvin, 2003, Nature Medicine.

Viraemia suppressed in HIV-1-infected humans by broadly neutralizing antibody 3BNC117

Michael S. Seaman, Florian Klein, Anthony P. West, 2015, Nature.

HLA-C cell surface expression and control of HIV / AIDS correlate with a variant upstream of HLA-C

D. Ge, J. Goedert, M. Carrington, 2009 .

Differential Ability of Primary HIV-1 Nef Isolates To Downregulate HIV-1 Entry Receptors

H. Jessen, T. Miura, B. Walker, 2015, Journal of Virology.

HIV-1 Viral Escape in Infancy Followed by Emergence of a Variant-Specific CTL Response1

Philip J. R. Goulder, Todd M. Allen, Simon Mallal, 2005, The Journal of Immunology.

Frequent Detection of Escape from Cytotoxic T-Lymphocyte Recognition in Perinatal Human Immunodeficiency Virus (HIV) Type 1 Transmission: the Ariel Project for the Prevention of Transmission of HIV from Mother to Infant

B. Walker, B. Korber, Steven Wolinsky, 1999, Journal of Virology.

Evolution and Diversity of Immune Responses during Acute HIV Infection.

B. Walker, S. Kazer, A. Shalek, 2020, Immunity.

A Reproducibility-Based Computational Framework Identifies an Inducible, Enhanced Antiviral State in Dendritic Cells from HIV-1 Elite Controllers

B. Walker, S. Kazer, Kellie E Kolb, 2018, Genome Biology.

Cutting Edge: Prolonged Exposure to HIV Reinforces a Poised Epigenetic Program for PD-1 Expression in Virus-Specific CD8 T Cells

Todd M. Allen, T. Miura, B. Walker, 2013, The Journal of Immunology.

Prolonged Exposure to HIV Reinforces a Poised Epigenetic Program for PD-1 Expression in Virus-Specific CD8 T Cells

Rafi, Todd M. Allen, B. Walker, 2022 .

Impact of Kaposi sarcoma-associated herpesvirus (KSHV) burden and HIV coinfection on the detection of T cell responses to KSHV ORF73 and ORF65 proteins.

B. Walker, C. Brander, D. Scadden, 2005, The Journal of infectious diseases.

Defective Immune Function of Primary Effusion Lymphoma Cells is Associated with Distinct KSHV Gene Expression Profiles

Christian Brander, B. Walker, Yidong Chen, 2004, Leukemia & lymphoma.

Absence of biologically important Kaposi sarcoma-associated herpesvirus gene products and virus-specific cellular immune responses in multiple myeloma.

B. Walker, C. Brander, D. Scadden, 2002, Blood.

Modulation of host immune responses by clinically relevant human DNA and RNA viruses.

B. Walker, C. Brander, 2000, Current opinion in microbiology.

Perforin Expression Directly Ex Vivo by HIV-Specific CD8+ T-Cells Is a Correlate of HIV Elite Control

F. Pereyra, B. Walker, M. Lederman, 2010, PLoS pathogens.

HIV-1–specific cytotoxicity is preferentially mediated by a subset of CD8+ T cells producing both interferon-γ and tumor necrosis factor–α

Todd M. Allen, E. Rosenberg, M. Altfeld, 2004 .

β-Chemokines are released from HIV-1-specific cytolytic T-cell granules complexed to proteoglycans

B. Walker, O. Yang, S. Kalams, 1998, Nature.

Ex vivo analysis of human memory CD4 T cells specific for hepatitis C virus using MHC class II tetramers.

B. Walker, P. Klenerman, G. Lauer, 2003, The Journal of clinical investigation.

Concanamycin A counteracts HIV-1 Nef to enhance immune clearance of infected primary cells by cytotoxic T lymphocytes

B. Walker, J. Hurley, D. Sherman, 2020, Proceedings of the National Academy of Sciences.

Defining the directionality and quality of influenza virus-specific CD8+ T cell cross-reactivity in individuals infected with hepatitis C virus.

B. Walker, P. Klenerman, G. Lauer, 2008, The Journal of clinical investigation.

High Level of PD-1 Expression on Hepatitis C Virus (HCV)-Speciﬁc CD8 (cid:1) and CD4 (cid:1) T Cells during Acute HCV Infection, Irrespective of Clinical Outcome (cid:1)

Todd M. Allen, B. Walker, P. Klenerman, 2008 .

CD8 Epitope Escape and Reversion in Acute HCV Infection

Todd M. Allen, B. Walker, P. Klenerman, 2004, The Journal of experimental medicine.

Progress in Defining CD4 Helper Cell Responses in Chronic Viral Infections

B. Walker, C. Day, 2003, The Journal of experimental medicine.

T cell failure in hepatitis C virus infection.

B. Walker, P. Klenerman, G. Lauer, 2002, Viral immunology.

A hairpin turn in a class II MHC-bound peptide orients residues outside the binding groove for T cell recognition.

Philip J Norris, B. Walker, L. Stern, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Toward T Cell-Mediated Control or Elimination of HIV Reservoirs: Lessons From Cancer Immunology

B. Walker, M. Maus, G. Mylvaganam, 2019, Front. Immunol..

IL-21 induces antiviral microRNA-29 in CD4 T cells to limit HIV-1 infection

B. Walker, L. Glimcher, D. Kwon, 2015, Nature Communications.

Integrated Single-Cell Analysis of Multicellular Immune Dynamics during Hyper-Acute HIV-1 Infection

B. Walker, T. Ndung’u, C. Ziegler, 2019, bioRxiv.

Polymorphisms of large effect explain the majority of the host genetic contribution to variation of HIV-1 virus load

D. Goldstein, J. Goedert, M. Carrington, 2015, Proceedings of the National Academy of Sciences.

Human immunodeficiency virus type 1 evolution in vivo tracked by DNA heteroduplex mobility assays

B. Walker, J. Mullins, E. Delwart, 1994, Journal of virology.

The great escape – AIDS viruses and immune control

B. Walker, P. Goulder, Bruce D. Walker, 1999, Nature Medicine.

Potent Cell-Intrinsic Immune Responses in Dendritic Cells Facilitate HIV-1-Specific T Cell Immunity in HIV-1 Elite Controllers

B. Walker, Xu G. Yu, Zhengyu Ouyang, 2015, PLoS pathogens.

Constraints on HIV-1 evolution and immunodominance revealed in monozygotic adult twins infected with the same virus

Christos J. Petropoulos, Terri Wrin, Lidia Ruiz, 2006, The Journal of experimental medicine.

Cervicovaginal bacteria are a major modulator of host inflammatory responses in the female genital tract.

Melis N. Anahtar, C. Nusbaum, C. Huttenhower, 2015, Immunity.

Lactobacillus‐Deficient Cervicovaginal Bacterial Communities Are Associated with Increased HIV Acquisition in Young South African Women

Melis N. Anahtar, C. Huttenhower, B. Walker, 2017, Immunity.

Essential for Viral Replication Escape Associated with Targeting a Sequence Nonprogressor : Constraints on Immune Recognized from a Long-Term Conserved CTL Epitope in HIV-1 p 24 Molecular and Functional Analysis of a

B. Walker, T. Harrer, S. Buchbinder, 1999 .

Techniques in HIV Research

B. Walker, A. Aldovini, Bruce D. Walker, 1990, Palgrave Macmillan UK.

Innate Lymphoid Cells Are Depleted Irreversibly during Acute HIV-1 Infection in the Absence of Viral Suppression.

B. Walker, T. Ndung’u, S. Kazer, 2016, Immunity.

SARS-CoV-2 viral load is associated with increased disease severity and mortality

Michael D Healy, Kelsey K. Finn, David A. Drew, 2020, Nature Communications.

Analysis of Major Histocompatibility Complex-Bound HIV Peptides Identified from Various Cell Types Reveals Common Nested Peptides and Novel T Cell Responses

B. Walker, A. Riemer, S. Le Gall, 2016, Journal of Virology.

replication of the primary virus

Todd M. Allen, E. Rosenberg, M. Altfeld, 2002 .

Infection of CD127+ (Interleukin-7 Receptor+) CD4+ Cells and Overexpression of CTLA-4 Are Linked to Loss of Antigen-Specific CD4 T Cells during Primary Human Immunodeficiency Virus Type 1 Infection

E. Rosenberg, B. Walker, J. Kaldor, 2006, Journal of Virology.

Loss of Bcl-6-Expressing T Follicular Helper Cells and Germinal Centers in COVID-19

Kelsey K. Finn, B. Walker, Xu G. Yu, 2020, Cell.

A genome-wide CRISPR screen identifies a restricted set of HIV host dependency factors

Nir Hacohen, Nevan J Krogan, David M Sabatini, 2016, Nature Genetics.

HLA class-I-peptide stability mediates CD8+ T cell immunodominance hierarchies and facilitates HLA-associated immune control of HIV

B. Walker, E. Rossin, N. Singh, 2021, Cell reports.

HIV-infected macrophages resist efficient NK cell-mediated killing while preserving inflammatory cytokine responses.

B. Walker, H. Ploegh, K. Clayton, 2021, Cell host & microbe.

Latent HIV reservoirs exhibit inherent resistance to elimination by CD8+ T cells

R. Siliciano, B. Walker, D. Nixon, 2018, The Journal of clinical investigation.

Chimeric immune receptor T cells bypass class I requirements and recognize multiple cell types relevant in HIV-1 infection.

B. Walker, O. Yang, M. E. Severino, 2003, Virology.

Association between injectable progestin-only contraceptives and HIV acquisition and HIV target cell frequency in the female genital tract in South African women: a prospective cohort study.

Melis N. Anahtar, B. Walker, T. Ndung’u, 2016, The Lancet. Infectious diseases.

Relative Resistance of HLA-B to Downregulation by Naturally Occurring HIV-1 Nef Sequences

B. Walker, Y. Xiong, Z. Brumme, 2016, mBio.

Genetic interplay between HLA-C and MIR148A in HIV control and Crohn disease

F. Pereyra, M. Carrington, B. Walker, 2013, Proceedings of the National Academy of Sciences.

Immunogenetics of spontaneous control of HIV.

M. Carrington, B. Walker, 2012, Annual review of medicine.

Differential microRNA regulation of HLA-C expression and its association with HIV control

F. Pereyra, M. Carrington, B. Walker, 2011, Nature.

The immune response to AIDS virus infection: good, bad, or both?

B. Walker, S. Deeks, 2004, The Journal of clinical investigation.

HIV Controllers Exhibit Effective CD8+ T Cell Recognition of HIV-1-Infected Non-activated CD4+ T Cells

B. Walker, S. Le Gall, R. B. Jones, 2019, Cell reports.

HIV-specific cytotoxic T lymphocytes in seropositive individuals

B. Walker, R. Schooley, M. Hirsch, 1987, Nature.

Profound Treg perturbations correlate with COVID-19 severity

B. Walker, C. Benoist, Xu G. Yu, 2020, bioRxiv.

Hepatitis C virus (HCV)-specific cytotoxic T lymphocytes recognize epitopes in the core and envelope proteins of HCV

B. Walker, M. Houghton, D. Dudley, 1993, Journal of virology.

HLA tapasin independence: broader peptide repertoire and HIV control

J. Goedert, M. Carrington, B. Walker, 2020, Proceedings of the National Academy of Sciences.

HIV-1 DNA sequence diversity and evolution during acute subtype C infection

B. Walker, T. Ndung’u, Xu G. Yu, 2019, Nature Communications.

Selection of an HLA-C*03:04-Restricted HIV-1 p24 Gag Sequence Variant Is Associated with Viral Escape from KIR2DL3+ Natural Killer Cells: Data from an Observational Cohort in South Africa

Jaclyn K. Mann, M. Altfeld, M. Carrington, 2015, PLoS medicine.

Impact of HLA-driven HIV adaptation on virulence in populations of high HIV seroprevalence

Angela R. McLean, John Frater, Jonathan M. Carlson, 2014, Proceedings of the National Academy of Sciences.

Association Study of Common Genetic Variants and HIV-1 Acquisition in 6,300 Infected Cases and 7,200 Controls

Paul J. McLaren, Jacques Fellay, David B. Goldstein, 2013, PLoS pathogens.

Association of HLA-DRB1-restricted CD4+ T cell responses with HIV immune control

M. Carrington, B. Walker, Y. Qi, 2013, Nature Medicine.

Possession of HLA class II DRB1*1303 associates with reduced viral loads in chronic HIV-1 clade C and B infection.

M. Carrington, B. Walker, Y. Qi, 2011, The Journal of infectious diseases.

Adaptation of HIV-1 to human leukocyte antigen class I

David Heckerman, John Frater, Rodney Phillips, 2009, Nature.

Evidence of Differential HLA Class I-Mediated Viral Evolution in Functional and Accessory/Regulatory Genes of HIV-1

David Heckerman, Tanmoy Bhattacharya, Christian Brander, 2007, PLoS pathogens.

Control of HIV-1 viremia and protection from AIDS are associated with HLA-Bw4 homozygosity

E. Rosenberg, B. Walker, E. Vittinghoff, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Amino-Acid Co-Variation in HIV-1 Gag Subtype C: HLA-Mediated Selection Pressure and Compensatory Dynamics

Philip J. R. Goulder, David E. Heckerman, Christian Brander, 2010, PloS one.

Natural HIV-1 Nef Polymorphisms Impair SERINC5 Downregulation Activity

B. Walker, Nirmin Alsahafi, A. Finzi, 2019, Cell reports.

Dynamic range of Nef functions in chronic HIV-1 infection.

B. Walker, Z. Brumme, M. Brockman, 2013, Virology.

Nef-Mediated Resistance of Human Immunodeficiency Virus Type 1 to Antiviral Cytotoxic T Lymphocytes

B. Walker, O. Yang, S. Kalams, 2002, Journal of Virology.

Reactivation of latent HIV-1 by inhibition of BRD4.

A. Brass, S. Elledge, B. Walker, 2012, Cell reports.

Rev activity determines sensitivity of HIV-1-infected primary T cells to CTL killing.

Tracey M. Filzen, M. Altfeld, B. Walker, 2003, Immunity.

Structure-guided T cell vaccine design for SARS-CoV-2 variants and sarbecoviruses

B. Walker, E. Rossin, N. Singh, 2021, Cell.

Viral epitope profiling of COVID-19 patients reveals cross-reactivity and correlates of severity

N. Hacohen, S. Elledge, B. Walker, 2020, Science.

T cell reactivity to the SARS-CoV-2 Omicron variant is preserved in most but not all individuals

B. Walker, V. Naranbhai, A. Balazs, 2022, Cell.

CD8+ cells in human immunodeficiency virus type I pathogenesis: cytolytic and noncytolytic inhibition of viral replication.

B. Walker, O. Yang, 1997, Advances in immunology.

Recognition of HIV-1 Peptides by Host CTL Is Related to HIV-1 Similarity to Human Proteins

D. Heckerman, B. Walker, D. Nickle, 2007, PloS one.

HIV-1 Integration Landscape during Latent and Active Infection

Florian Klein, Gerald H. Learn, Clara Lehmann, 2015, Cell.

HIV-1-Specific Cytotoxic T Lymphocytes

B. Walker, 1990 .

Profound Treg perturbations correlate with COVID-19 severity

B. Walker, C. Benoist, Xu G. Yu, 2021, Proceedings of the National Academy of Sciences.

Association of TRIM22 with the Type 1 Interferon Response and Viral Control during Primary HIV-1 Infection

A. Brass, B. Walker, T. Ndung’u, 2010, Journal of Virology.

Association of TRIM 22 with the Type 1 Interferon Response and Viral Control during Primary HIV-1 Infection

A. Brass, B. Walker, J. Luban, 2010 .

Integrative genomic analysis of HIV-specific CD8+ T cells reveals that PD-1 inhibits T cell function by upregulating BATF

Björn Nilsson, Gordon J. Freeman, Quentin Eichbaum, 2010, Nature Medicine.

Distinct viral reservoirs in individuals with spontaneous control of HIV-1

R. Siliciano, A. Engelman, B. Walker, 2020, Nature.

A unique viral reservoir landscape in HIV-1 elite controllers

R. Siliciano, A. Engelman, B. Walker, 2020, Nature.

A unique viral reservoir landscape in HIV-1 elite controllers

R. Siliciano, A. Engelman, B. Walker, 2020, Nature.

Large-scale amplification, cloning and sequencing of near full-length HIV-1 subtype C genomes.

B. Walker, G. Learn, J. Mullins, 2006, Journal of virological methods.

HLA-B57-Restricted Cytotoxic T-Lymphocyte Activity in a Single Infected Subject toward Two Optimal Epitopes, One of Which Is Entirely Contained within the Other

B. Walker, P. Goulder, Yanhua Tang, 2000, Journal of Virology.

T lymphocyte responses in HIV-1 infection: implications for vaccine development.

B. Walker, C. Brander, Bruce D. Walker, 1999, Current opinion in immunology.

CD8+ T cells in HIV control, cure and prevention

B. Walker, G. Gaiha, D. Collins, 2020, Nature Reviews Immunology.

HIV-1 specific CD8+ T cells with an effector phenotype and control of viral replication

Todd M. Allen, E. Rosenberg, M. Altfeld, 2004, The Lancet.

Unravelling the mechanisms of durable control of HIV-1

B. Walker, Xu G. Yu, Bruce D. Walker, 2013, Nature Reviews Immunology.

Human immunodeficiency virus controllers: mechanisms of durable virus control in the absence of antiretroviral therapy.

B. Walker, S. Deeks, Steven G Deeks, 2007, Immunity.

Human Immunodeficiency Virus Type 1 Populations in Blood and Semen

B. Walker, D. Katzenstein, G. Learn, 1998, Journal of Virology.

Killer cell immunoglobulin–like receptor 3DL1 variation modifies HLA-B*57 protection against HIV-1

J. Goedert, M. Carrington, B. Walker, 2018, The Journal of clinical investigation.

Killer cell immunoglobulin – like receptor 3 DL 1 variation modifies HLA-B * 57 protection against HIV-1

J. Goedert, M. Carrington, B. Walker, 2018 .

Killer cell immunoglobulin – like receptor 3 DL 1 variation modifies HLA-B * 57 protection against HIV-1 Maureen

J. Goedert, M. Carrington, B. Walker, 2018 .

HLA-B*14:02-Restricted Env-Specific CD8+ T-Cell Activity Has Highly Potent Antiviral Efficacy Associated with Immune Control of HIV Infection

J. Goedert, M. Carrington, B. Walker, 2017, Journal of Virology.

HIV Molecular Immunology 2015

Karina Yusim, Bette T. Korber, Christian Brander, 2016 .

The Breadth of Expandable Memory CD8+ T Cells Inversely Correlates with Residual Viral Loads in HIV Elite Controllers

F. Pereyra, B. Walker, Z. Ndhlovu, 2015, Journal of Virology.

CD8+ TCR Bias and Immunodominance in HIV-1 Infection

B. Walker, T. Ndung’u, S. Buus, 2015, The Journal of Immunology.

High Frequency of Transmitted HIV-1 Gag HLA Class I-Driven Immune Escape Variants but Minimal Immune Selection over the First Year of Clade C Infection

Jaclyn K. Mann, B. Walker, T. Ndung’u, 2015, PloS one.

Anti-APOBEC3G Activity of HIV-1 Vif Protein Is Attenuated in Elite Controllers

H. Jessen, F. Pereyra, T. Miura, 2015, Journal of Virology.

Impaired Nef Function Is Associated with Early Control of HIV-1 Viremia

E. Rosenberg, H. Jessen, F. Pereyra, 2014, Journal of Virology.

Fitness Replicative Rare p24 Gag Mutation on HIV-1 Intersubtype Differences in the Effect of a

Jaclyn K. Mann, T. Miura, B. Walker, 2014 .

Early Control of HIV-1 Viremia Impaired Nef Function Is Associated with

E. Rosenberg, H. Jessen, F. Pereyra, 2014 .

The T-cell response to HIV.

B. Walker, A. McMichael, 2012, Cold Spring Harbor perspectives in medicine.

HIV and HLA class I: an evolving relationship.

B. Walker, P. Goulder, Bruce D Walker, 2012, Immunity.

Immune Responses Associated to Viral Control

F. Pereyra, B. Walker, 2012 .

Compensated CD8 Escape Mutations Transmission and Long-Term Stability of

E. Rosenberg, B. Walker, Yaoyu E. Wang, 2012 .

Definition of the viral targets of protective HIV-1-specific T cell responses

Todd M. Allen, D. Heckerman, B. Walker, 2011, Journal of Translational Medicine.

HLA-B*57 Micropolymorphism Shapes HLA Allele-Specific Epitope Immunogenicity, Selection Pressure, and HIV Immune Control

B. Walker, T. Ndung’u, S. Buus, 2011, Journal of Virology.

Factors associated with viral rebound in HIV-1-infected individuals enrolled in a therapeutic HIV-1 gag vaccine trial.

M. Carrington, B. Walker, R. Schooley, 2011, The Journal of infectious diseases.

Reduced Replication Capacity of NL4-3 Recombinant Viruses Encoding Reverse Transcriptase–Integrase Sequences From HIV-1 Elite Controllers

Todd M. Allen, D. Heckerman, F. Pereyra, 2011, Journal of acquired immune deficiency syndromes.

Spontaneous control of HCV is associated with expression of HLA-B 57 and preservation of targeted epitopes.

Raymond T Chung, Todd M. Allen, Todd M Allen, 2011, Gastroenterology.

HLA-Cw*03-Restricted CD8+ T-Cell Responses Targeting the HIV-1 Gag Major Homology Region Drive Virus Immune Escape and Fitness Constraints Compensated for by Intracodon Variation

B. Walker, T. Ndung’u, J. Prado, 2010, Journal of Virology.

Gag-Protease-Mediated Replication Capacity in HIV-1 Subtype C Chronic Infection: Associations with HLA Type and Clinical Parameters

David Heckerman, Carl M. Kadie, Elena Losina, 2010, Journal of Virology.

Impaired Replication Capacity of Acute/Early Viruses in Persons Who Become HIV Controllers

E. Rosenberg, H. Jessen, F. Pereyra, 2010, Journal of Virology.

Replicative Capacity of Human Immunodeficiency Virus Type 1 Transmitted from Mother to Child Is Associated with Pediatric Disease Progression Rate

B. Walker, T. Ndung’u, J. Prado, 2009, Journal of Virology.

Evolution of HLA-B*5703 HIV-1 escape mutations in HLA-B*5703–positive individuals and their transmission recipients

B. Walker, T. Ndung’u, J. Prado, 2009, The Journal of experimental medicine.

HLA-Associated Viral Mutations Are Common in Human Immunodeficiency Virus Type 1 Elite Controllers

F. Pereyra, T. Miura, B. Walker, 2009, Journal of Virology.

HLA FOOTPRINTS ON HIV-1 ARE ASSOCIATED WITH 1

Todd M. Allen, D. Heckerman, B. Walker, 2009 .

Transmission and Long-Term Stability of Compensated CD8 Escape Mutations

Todd M. Allen, E. Rosenberg, H. Jessen, 2008, Journal of Virology.

Deficiency of HIV-Gag-Specific T Cells in Early Childhood Correlates with Poor Viral Containment1

B. Walker, M. Feeney, Yanhua Tang, 2008, The Journal of Immunology.

Phylogenetic Dependency Networks: Inferring Patterns of CTL Escape and Codon Covariation in HIV-1 Gag

David Heckerman, Carl Myers Kadie, Bruce D. Walker, 2008, PLoS Comput. Biol..

HLA-Associated Alterations in Replication Capacity of Chimeric NL4-3 Viruses Carrying gag-protease from Elite Controllers of Human Immunodeficiency Virus Type 1

Todd M. Allen, D. Heckerman, F. Pereyra, 2008, Journal of Virology.

Human leukocyte antigen-specific polymorphisms in HIV-1 Gag and their association with viral load in chronic untreated infection

David Heckerman, Christian Brander, Nicole Frahm, 2008, AIDS.

Central Role of Reverting Mutations in HLA Associations with Human Immunodeficiency Virus Set Point

D. Heckerman, B. Walker, C. Kadie, 2008, Journal of Virology.

Increased Sequence Diversity Coverage Improves Detection of HIV-Specific T Cell Responses1

Todd M. Allen, T. Miura, B. Walker, 2007, The Journal of Immunology.

Human immunodeficiency virus type 1 specific cytotoxic T lymphocyte responses in Chinese infected with HIV-1 B'/C Recombinant (CRF07_BC)

M. Altfeld, B. Walker, Xu G. Yu, 2007, Retrovirology.

Escape and Compensation from Early HLA-B57-Mediated Cytotoxic T-Lymphocyte Pressure on Human Immunodeficiency Virus Type 1 Gag Alter Capsid Interactions with Cyclophilin A

Todd M. Allen, Cynthia A. Derdeyn, Eric Hunter, 2007, Journal of Virology.

Philip J. R. Goulder, Christian Brander, Eric Hunter, 2007, Journal of Virology.

Recognition of a Defined Region within p24 Gag by CD8+ T Cells during Primary Human Immunodeficiency Virus Type 1 Infection in Individuals Expressing Protective HLA Class I Alleles

E. Rosenberg, M. Altfeld, B. Walker, 2007, Journal of Virology.

Effective T-Cell Responses Select Human Immunodeficiency Virus Mutants and Slow Disease Progression

B. Walker, H. Günthard, C. Brander, 2007, Journal of Virology.

Control of Human Immunodeficiency Virus Type 1 Is Associated with HLA-B*13 and Targeting of Multiple Gag-Specific CD8+ T-Cell Epitopes

F. Pereyra, B. Walker, J. Mullins, 2007, Journal of Virology.

Improves Detection of HIV-Specific T Cell Increased Sequence Diversity Coverage

Todd M. Allen, T. Miura, B. Walker, 2007 .

Differential Selection Pressure Exerted on HIV by CTL Targeting Identical Epitopes but Restricted by Distinct HLA Alleles from the Same HLA Supertype1

B. Walker, J. Mullins, C. Brander, 2006, The Journal of Immunology.

the Same HLA Supertype but Restricted by Distinct HLA Alleles from HIV by CTL Targeting Identical Epitopes Differential Selection Pressure Exerted on

Gareth, B. Walker, J. Mullins, 2006 .

Dominant influence of HLA-B in mediating the potential co-evolution of HIV and HLA

Bette Korber, Michael Bunce, Philip J. R. Goulder, 2004, Nature.

HIV evolution: CTL escape mutation and reversion after transmission

Todd M. Allen, T A Roach, M. Altfeld, 2004, Nature Medicine.

Influence of HLA-B57 on clinical presentation and viral control during acute HIV-1 infection

Todd M. Allen, E. Rosenberg, M. Altfeld, 2003, AIDS.

Mutually Exclusive T-Cell Receptor Induction and Differential Susceptibility to Human Immunodeficiency Virus Type 1 Mutational Escape Associated with a Two-Amino-Acid Difference between HLA Class I Subtypes

Todd M. Allen, E. Rosenberg, F. Pereyra, 2006, Journal of Virology.

Lower Viral Loads and Slower CD4+ T-Cell Count Decline in MRKAd5 HIV-1 Vaccinees Expressing Disease-Susceptible HLA-B*58:02

B. Walker, J. Kublin, T. Ndung’u, 2016, Journal of Infectious Diseases.

HIV-Specific Cytolytic CD4 T Cell Responses During Acute HIV Infection Predict Disease Outcome

E. Rosenberg, H. Jessen, A. Brass, 2012, Science Translational Medicine.

Extended high viremics: a substantial fraction of individuals maintain high plasma viral RNA levels after acute HIV-1 subtype C infection

Victor De Gruttola, Vladimir Novitsky, Thumbi Ndung'u, 2011, AIDS.

Human Immunodeficiency Virus Type 1-Specific CD8+ T-Cell Responses during Primary Infection Are Major Determinants of the Viral Set Point and Loss of CD4+ T Cells

Anthony D. Kelleher, Hendrik Streeck, Eric S. Rosenberg, 2009, Journal of Virology.

Epidemiologically linked transmission of HIV-1 illustrates the impact of host genetics on virological outcome

Todd M. Allen, H. Jessen, M. Altfeld, 2009, AIDS.

Human Immunodeficiency Virus Type 1-Specific CD8+ T-Cell Responses during Primary Infection Are Major Determinants of the Viral Set Point and Loss of CD4+ T Cells

E. Rosenberg, H. Jessen, M. Altfeld, 2009, Journal of Virology.

Targeting of a CD8 T cell env epitope presented by HLA-B*5802 is associated with markers of HIV disease progression and lack of selection pressure.

D. Heckerman, B. Walker, D. Nickle, 2008, AIDS research and human retroviruses.

Treatment interruption to boost specific HIV immunity in acute infection

B. Walker, D. Kaufmann, 2007, Current opinion in HIV and AIDS.

Selective Escape from CD8+ T-Cell Responses Represents a Major Driving Force of Human Immunodeficiency Virus Type 1 (HIV-1) Sequence Diversity and Reveals Constraints on HIV-1 Evolution

Christian Brander, Eric S. Rosenberg, Todd M. Allen, 2005, Journal of Virology.

Persistent Recognition of Autologous Virus by High-Avidity CD8 T Cells in Chronic, Progressive Human Immunodeficiency Virus Type 1 Infection

Todd M. Allen, B. Walker, M. Addo, 2004, Journal of Virology.

Characteristics of the intrahepatic cytotoxic T lymphocyte response in chronic hepatitis C virus infection

B. Walker, M. Koziel, 2004, Springer Seminars in Immunopathology.

HIV-1-specific cytotoxic T lymphocytes and the control of HIV-1 replication

B. Walker, C. Jassoy, 2004, Springer Seminars in Immunopathology.

Immunologic control of HIV-1.

B. Walker, R. Gandhi, 2002, Annual review of medicine.

Human immunodeficiency virus pathogenesis and prospects for immune control in patients with established infection.

B. Walker, D. Cohen, Daniel E. Cohen, 2001, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Substantial Differences in Specificity of HIV-Specific Cytotoxic T Cells in Acute and Chronic HIV Infection

E. Rosenberg, M. Altfeld, B. Walker, 2001, The Journal of experimental medicine.

Immunopathogenesis of HIV-1 infection.

B. Walker, H. Cao, Huyen Cao, 2000, Clinics in dermatology.

Differential Narrow Focusing of Immunodominant Human Immunodeficiency Virus Gag-Specific Cytotoxic T-Lymphocyte Responses in Infected African and Caucasoid Adults and Children

E. Rosenberg, M. Altfeld, B. Walker, 2000, Journal of Virology.

Plasma RNA viral load as measured by the branched DNA and nucleic acid sequence-based amplification assays of HIV-1 subtypes A and D in Uganda.

B. Walker, A. Caliendo, D. Hom, 1999, Journal of acquired immune deficiency syndromes.

Improved CD4 lymphocyte outgrowth in response to effective antiretroviral therapy.

B. Walker, M. Hirsch, J. Martinez-Picado, 1999, The Journal of infectious diseases.

Lack of strong immune selection pressure by the immunodominant, HLA-A*0201-restricted cytotoxic T lymphocyte response in chronic human immunodeficiency virus-1 infection.

R P Johnson, B. Walker, B. Korber, 1998, The Journal of clinical investigation.

Human immunodeficiency virus type 1-specific cytotoxic T lymphocytes release gamma interferon, tumor necrosis factor alpha (TNF-alpha), and TNF-beta when they encounter their target antigens

B. Walker, T. Harrer, R. Johnson, 1993, Journal of virology.

Innate lymphoid cells and disease tolerance in SARS-CoV-2 infection

B. Walker, Xu G. Yu, J. Luban, 2021, medRxiv.

Longitudinal and cross-sectional analysis of cytotoxic T lymphocyte responses and their relationship to vertical human immunodeficiency virus transmission. ARIEL Project Investigators.

B. Walker, B. Korber, D. Ho, 1998, The Journal of infectious diseases.

Longitudinal and Cross-Sectional Analysis of Cytotoxic T Lymphocyte (CTL) Responses and their Relationship to Vertical HIV Transmission

B. Walker, B. Korber, D. Ho, 1998 .

Longitudinal and Cross-Sectional Analysis of Cytotoxic T Lymphocyte Responses and Their Relationship to Vertical Human Immunodeficiency Virus Transmission

B. Walker, B. Korber, D. Ho, 1998 .

Liver-derived CTL in hepatitis C virus infection: breadth and specificity of responses in a cohort of persons with chronic infection.

B. Walker, C. Rice, M. Houghton, 1998, Journal of immunology.

a Cohort of Persons with Chronic Infection in Infection: Breadth and Specificity of Responses Liver-Derived CTL in Hepatitis C Virus

B. Walker, C. Rice, M. Houghton, 1998 .

HIV-1 reverse transcriptase is a target for cytotoxic T lymphocytes in infected individuals.

B. Walker, R. Schooley, M. Hirsch, 1988, Science.

The role of IFN-γ Elispot assay in HIV vaccine research

Hendrik Streeck, Nicole Frahm, B. Walker, 2009, Nature Protocols.

High resolution analysis of cellular immune responses in resolved and persistent hepatitis C virus infection.

Todd M. Allen, B. Walker, P. Klenerman, 2004, Gastroenterology.

TCR clonotypes modulate the protective effect of HLA class I molecules in HIV-1 infection

Todd M. Allen, F. Pereyra, T. Miura, 2012, Nature Immunology.

Differences in the Selection Bottleneck between Modes of Sexual Transmission Influence the Genetic Composition of the HIV-1 Founder Virus

Sergei L. Kosakovsky Pond, Philip J Norris, Todd M. Allen, 2016, PLoS pathogens.

Upregulation of CTLA-4 by HIV-specific CD4+ T cells correlates with disease progression and defines a reversible immune dysfunction

E. Rosenberg, F. Pereyra, T. Miura, 2007, Nature Immunology.

Antigen-specific antibody Fc glycosylation enhances humoral immunity via the recruitment of complement

D. Lauffenburger, B. Walker, D. Richman, 2018, Science Immunology.

Temporal changes in T cell subsets and expansion of cytotoxic CD4+ T cells in the lungs in severe COVID-19

Han Liu, B. Walker, Xu G. Yu, 2022, Clinical Immunology.

T cell reactivity to the SARS-CoV-2 Omicron variant is preserved in most but not all prior infected and vaccinated individuals

B. Walker, V. Naranbhai, A. Balazs, 2022, medRxiv.

Allelic variation in class I HLA determines CD8+ T cell repertoire shape and cross-reactive memory responses to SARS-CoV-2

Michael D Healy, Kelsey K. Finn, Benjamin P. Roscoe, 2021, Science Immunology.

Nef-mediated down-regulation of CD4 and HLA class I in HIV-1 subtype C infection: association with disease progression and influence of immune pressure.

Jaclyn K. Mann, B. Walker, S. Omarjee, 2014, Virology.

T cell receptor clonotypes modulate the protective effect of HLA class I alleles in HIV-1 infection

Todd M. Allen, F. Pereyra, T. Miura, 2013 .

Aminopeptidase Substrate Preference Affects HIV Epitope Presentation and Predicts Immune Escape Patterns in HIV-Infected Individuals

B. Walker, J. Carlson, S. Le Gall, 2012, The Journal of Immunology.

Differential Neutralization of Human Immunodeficiency Virus (HIV) Replication in Autologous CD4 T Cells by HIV-Specific Cytotoxic T Lymphocytes

Todd M. Allen, F. Pereyra, T. Miura, 2009, Journal of Virology.

A viral CTL escape mutation leading to immunoglobulin-like transcript 4–mediated functional inhibition of myelomonocytic cells

Todd M. Allen, E. Rosenberg, F. Pereyra, 2007, The Journal of experimental medicine.

Portable flanking sequences modulate CTL epitope processing.

B. Walker, S. Le Gall, P. Stamegna, 2007, The Journal of clinical investigation.

Human Immunodeficiency Virus-Specific CD8+ T-Cell Activity Is Detectable from Birth in the Majority of In Utero-Infected Infants

B. Walker, W. Mphatswe, P. Goulder, 2007, Journal of Virology.

Selective Depletion of High-Avidity Human Immunodeficiency Virus Type 1 (HIV-1)-Specific CD8+ T Cells after Early HIV-1 Infection

Eric S. Rosenberg, Todd M. Allen, E. Rosenberg, 2007, Journal of Virology.

Identification of HLA-A11-restricted HIV-1-specific cytotoxic T-lymphocyte epitopes in China.

M. Altfeld, B. Walker, Xu G. Yu, 2007, Current HIV research.

HLA Alleles Associated with Delayed Progression to AIDS Contribute Strongly to the Initial CD8+ T Cell Response against HIV-1

Todd M. Allen, E. Rosenberg, H. Jessen, 2006, PLoS medicine.

The challenges of host and viral diversity in HIV vaccine design.

B. Walker, C. Brander, N. Frahm, 2006, Current opinion in immunology.

Relative Dominance of Gag p24-Specific Cytotoxic T Lymphocytes Is Associated with Human Immunodeficiency Virus Control

Bette T. Korber, Christian Brander, Todd M. Allen, 2006, Journal of Virology.

De Novo Generation of Escape Variant-Specific CD8+ T-Cell Responses following Cytotoxic T-Lymphocyte Escape in Chronic Human Immunodeficiency Virus Type 1 Infection

Galit Alter, Christian Brander, Eric S. Rosenberg, 2005, Journal of Virology.

The Majority of Currently Circulating Human Immunodeficiency Virus Type 1 Clade B Viruses Fail To Prime Cytotoxic T-Lymphocyte Responses against an Otherwise Immunodominant HLA-A2-Restricted Epitope: Implications for Vaccine Design

Todd M. Allen, E. Rosenberg, M. Altfeld, 2005, Journal of Virology.

Enhanced Detection of Human Immunodeficiency Virus Type 1-Specific T-Cell Responses to Highly Variable Regions by Using Peptides Based on Autologous Virus Sequences

Todd M. Allen, E. Rosenberg, M. Altfeld, 2003, Journal of Virology.

Consistent Patterns in the Development and Immunodominance of Human Immunodeficiency Virus Type 1 (HIV-1)-Specific CD8+ T-Cell Responses following Acute HIV-1 Infection

Philip J. R. Goulder, Eric S. Rosenberg, E. Rosenberg, 2002, Journal of Virology.

Mother-to-child transmission of HIV infection and CTL escape through HLA-A2-SLYNTVATL epitope sequence variation.

B. Walker, E. Holmes, C. Brander, 2001, Immunology letters.

Vpr Is Preferentially Targeted by CTL During HIV-1 Infection1

E. Rosenberg, M. Altfeld, B. Walker, 2001, The Journal of Immunology.

Evolution and transmission of stable CTL escape mutations in HIV infection

Michael Bunce, Robert Funkhouser, Christian Brander, 2001, Nature.

Efficient Processing of the Immunodominant, HLA-A*0201-Restricted Human Immunodeficiency Virus Type 1 Cytotoxic T-Lymphocyte Epitope despite Multiple Variations in the Epitope Flanking Sequences

W. Blattner, B. Walker, Steven Wolinsky, 1999, Journal of Virology.

Identification of overlapping HLA class I-restricted cytotoxic T cell epitopes in a conserved region of the human immunodeficiency virus type 1 envelope glycoprotein: definition of minimum epitopes and analysis of the effects of sequence variation

B. Walker, A. Trocha, R. Johnson, 1992, The Journal of experimental medicine.

Identifying HLA-Associated Polymorphisms in HIV-1

B. Walker, J. Carlson, A. Poon, 2016 .

Consistent Cytotoxic-T-Lymphocyte Targeting of Immunodominant Regions in Human Immunodeficiency Virus across Multiple Ethnicities

F. M. Marincola, Nicole Frahm, B. Walker, 2004, Journal of Virology.

Comprehensive Epitope Analysis of Human Immunodeficiency Virus Type 1 (HIV-1)-Specific T-Cell Responses Directed against the Entire Expressed HIV-1 Genome Demonstrate Broadly Directed Responses, but No Correlation to Viral Load

D. Strick, E. Rosenberg, M. Altfeld, 2003, Journal of Virology.

Tracking the culprit: HIV-1 evolution and immune selection revealed by single-genome amplification

B. Walker, Z. Brumme, 2009, The Journal of experimental medicine.

Antigen Load and Viral Sequence Diversification Determine the Functional Profile of HIV-1–Specific CD8+ T Cells

Todd M. Allen, E. Rosenberg, M. Altfeld, 2008, PLoS medicine.

Fully Differentiated HIV-1 Specific CD8+ T Effector Cells Are More Frequently Detectable in Controlled than in Progressive HIV-1 Infection

E. Rosenberg, M. Altfeld, B. Walker, 2007, PloS one.

Fluctuations of functionally distinct CD8+ T-cell clonotypes demonstrate flexibility of the HIV-specific TCR repertoire.

Joseph A Conrad, Coley B. Duncan, Todd M. Allen, 2006, Blood.

flexibility of the HIV-specific TCR repertoire T-cell clonotypes demonstrate + Fluctuations of functionally distinct CD 8

Joseph A Conrad, Coley B. Duncan, Todd M. Allen, 2006 .

Differential immunogenicity of HIV-1 clade C proteins in eliciting CD8+ and CD4+ cell responses.

M. Altfeld, B. Walker, Jason Harlow, 2005, The Journal of infectious diseases.

Limited Sequence Evolution within Persistently Targeted CD8 Epitopes in Chronic Human Immunodeficiency Virus Type 1 Infection

Todd M. Allen, Spyros A. Kalams, B. Walker, 2005, Journal of Virology.

Limited Durability of Viral Control following Treated Acute HIV Infection

E. Rosenberg, M. Altfeld, B. Walker, 2004, PLoS medicine.

Immune Escape Precedes Breakthrough Human Immunodeficiency Virus Type 1 Viremia and Broadening of the Cytotoxic T-Lymphocyte Response in an HLA-B27-Positive Long-Term-Nonprogressing Child

B. Walker, M. Feeney, P. Goulder, 2004, Journal of Virology.

Differences in the expressed HLA class I alleles effect the differential clustering of HIV type 1-specific T cell responses in infected Chinese and caucasians.

Todd M. Allen, M. Altfeld, B. Walker, 2004, AIDS research and human retroviruses.

HIV-1 Nef is preferentially recognized by CD8 T cells in primary HIV-1 infection despite a relatively high degree of genetic diversity

Bette Korber, Jessica Malenfant, Todd M. Allen, 2004, AIDS.

CD8+ T lymphocyte responses target functionally important regions of Protease and Integrase in HIV-1 infected subjects

E. Rosenberg, M. Altfeld, B. Walker, 2004, Journal of Translational Medicine.

Human Genetics and HIV-1 Infection

M. Altfeld, B. Walker, Xu G. Yu, 2004 .

CD 8 + T lymphocyte responses target functionally important regions of Protease and Integrase in HIV-1 infected subjects

E. Rosenberg, M. Altfeld, B. Walker, 2004 .

Gradual adaptation of HIV to human host populations: good or bad news?

B. Walker, C. Brander, 2003, Nature Medicine.

Impacts of Avidity and Specificity on the Antiviral Efficiency of HIV-1-Specific CTL 1

B. Walker, O. Yang, S. Kalams, 2003, The Journal of Immunology.

Antiviral Efficiency of HIV-1-Specific CTL Impacts of Avidity and Specificity on the

B. Walker, O. Yang, A. Trocha, 2003 .

Cytotoxic T-lymphocyte (CTL) responses directed against regulatory and accessory proteins in HIV-1 infection.

M. Altfeld, B. Walker, M. Addo, 2002, DNA and cell biology.

STI and beyond: the prospects of boosting anti-HIV immune responses.

Todd M. Allen, B. Walker, A. Kelleher, 2002, Trends in immunology.

Promises and pitfalls in the reconstitution of immunity in patients who have HIV-1 infection.

B. Walker, R. Gandhi, 2002, Current opinion in immunology.

Cellular immune responses against hepatitis C virus: the evidence base 2002

B. Walker, P. Klenerman, G. Lauer, 2002, Clinical and experimental immunology.

The HIV-1 regulatory proteins Tat and Rev are frequently targeted by cytotoxic T lymphocytes derived from HIV-1-infected individuals.

E. Rosenberg, M. Altfeld, B. Walker, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Identification of Novel HLA-A2-Restricted Human Immunodeficiency Virus Type 1-Specific Cytotoxic T-Lymphocyte Epitopes Predicted by the HLA-A2 Supertype Peptide-Binding Motif

John Sidney, Alessandro Sette, Brian Livingston, 2001, Journal of Virology.

During HIV-1 Infection Vpr Is Preferentially Targeted by CTL Rosenberg and

M. Altfeld, B. Walker, C. Brander, 2001 .

AIDS: Escape from the immune system

B. Walker, P. Goulder, 2000, Nature.

Immune control of HIV: the obstacles of HLA and viral diversity

Bette T. Korber, B. Walker, B. Korber, 2001, Nature Immunology.

A Microchip CD4 Counting Method for HIV Monitoring in Resource-Poor Settings

John T McDevitt, Bruce D Walker, Sanghamitra Mohanty, 2005, PLoS medicine.

Response Emergence of a Variant-Specific CTL HIV-1 Viral Escape in Infancy Followed by Altfeld ,

Todd M. Allen, M. Altfeld, B. Walker, 2005 .

Viral inhibition assay: a CD8 T cell neutralization assay for use in clinical trials of HIV-1 vaccine candidates.

B. Walker, E. Karita, O. Anzala, 2010, The Journal of infectious diseases.

High degree of inter-clade cross-reactivity of HIV-1-specific T cell responses at the single peptide level

Galit Alter, Christian Brander, M. Altfeld, 2005, AIDS.

Cellular immunity to human immunodeficiency virus type 1 (HIV-1) clades: relevance to HIV-1 vaccine trials in Uganda.

B. Walker, J. Ellner, R. Mugerwa, 2000, The Journal of infectious diseases.

Cytotoxic T-lymphocyte cross-reactivity among different human immunodeficiency virus type 1 clades: implications for vaccine development

B. Walker, B. Korber, S. Kalams, 1997, Journal of virology.

Efficient lysis of human immunodeficiency virus type 1-infected cells by cytotoxic T lymphocytes

R P Johnson, B. Walker, O. Yang, 1996, Journal of virology.

Immunological and virological impact of highly active antiretroviral therapy initiated during acute HIV-1 infection.

Todd M. Allen, H. Jessen, M. Altfeld, 2006, The Journal of infectious diseases.

Dendritic cells focus CTL responses toward highly conserved and topologically important HIV epitopes

B. Walker, B. Korber, J. Ananworanich, 2020, bioRxiv.

Saporin-conjugated tetramers identify efficacious anti-HIV CD8+ T-cell specificities

M. Altfeld, B. Walker, P. Klenerman, 2017, PloS one.

Magnitude and Kinetics of CD8+ T Cell Activation during Hyperacute HIV Infection Impact Viral Set Point.

K. Shekhar, B. Walker, A. Chakraborty, 2015, Immunity.

Tolerability and Efficacy of PI Versus NNRTI-Based Regimens in Subjects Receiving HAART During Acute or Early HIV Infection

B. Walker, J. Margolick, F. Vaida, 2009, Journal of acquired immune deficiency syndromes.

Fine specificity and cross-clade reactivity of HIV type 1 Gag-specific CD4+ T cells.

Todd M. Allen, E. Rosenberg, B. Walker, 2004, AIDS research and human retroviruses.

Ability of HIV-1 Nef to downregulate CD4 and HLA class I differs among viral subtypes

Rosemary M. McCloskey, Jaclyn K. Mann, B. Walker, 2013, Retrovirology.

Title Ability of HIV-1 Nef to downregulate CD 4 and HLA class I differs among viral subtypes Permalink

Rosemary M. McCloskey, Jaclyn K. Mann, B. Walker, 2013 .

Attenuation of multiple Nef functions in HIV-1 elite controllers

F. Pereyra, T. Miura, B. Walker, 2013, Retrovirology.

Virus-Specific CTL Responses Coinfection on the Immunodominance of Affinity , Functional Avidity , and Viral Impact of HLA-B Alleles , Epitope Binding Korber

D. Heckerman, B. Walker, B. Korber, 2006 .

Enhanced Anti-HIV Functional Activity Associated with Gag-Specific CD8 T-Cell Responses

M. Carrington, B. Walker, Y. Qi, 2010, Journal of Virology.

Characteristics and Outcomes of Initial Virologic Suppressors during Analytic Treatment Interruption in a Therapeutic HIV-1 gag Vaccine Trial

M. Carrington, B. Walker, R. Schooley, 2012, PloS one.

A high-throughput single-cell analysis of human CD8⁺ T cell functions reveals discordance for cytokine secretion and cytolysis.

J Christopher Love, Yvonne J Yamanaka, Navin Varadarajan, 2011, The Journal of clinical investigation.

A Novel Immunodominant CD8+ T Cell Response Restricted by a Common HLA-C Allele Targets a Conserved Region of Gag HIV-1 Clade CRF01_AE Infected Thais

Praphan Phanuphak, Christian Brander, Todd M. Allen, 2011, PloS one.

High-Functional-Avidity Cytotoxic T Lymphocyte Responses to HLA-B-Restricted Gag-Derived Epitopes Associated with Relative HIV Control

F. Pereyra, B. Walker, J. Sidney, 2011, Journal of Virology.

Mosaic HIV-1 Gag Antigens Can Be Processed and Presented to Human HIV-Specific CD8+ T Cells

B. Walker, T. Ndung’u, Z. Ndhlovu, 2011, The Journal of Immunology.

Immunodominant HIV-1-specific HLA-B- and HLA-C-restricted CD8+ T cells do not differ in polyfunctionality

M. Altfeld, B. Walker, T. Ndung’u, 2010, Virology.

Differential HIV epitope processing in monocytes and CD4 T cells affects cytotoxic T lymphocyte recognition.

B. Walker, S. Le Gall, E. Lazaro, 2009, The Journal of infectious diseases.

Loss of HIV-1–specific CD8+ T Cell Proliferation after Acute HIV-1 Infection and Restoration by Vaccine-induced HIV-1–specific CD4+ T Cells

Galit Alter, Eric S. Rosenberg, Daniel E. Kaufmann, 2004, The Journal of experimental medicine.

HIV-1-specific cytotoxicity is preferentially mediated by a subset of CD8(+) T cells producing both interferon-gamma and tumor necrosis factor-alpha.

Todd M. Allen, E. Rosenberg, M. Altfeld, 2004, Blood.

HLA-B57/B*5801 Human Immunodeficiency Virus Type 1 Elite Controllers Select for Rare Gag Variants Associated with Reduced Viral Replication Capacity and Strong Cytotoxic T-Lymphocyte Recognition

Todd M. Allen, F. Pereyra, T. Miura, 2009, Journal of Virology.

Genetic Characterization of Human Immunodeficiency Virus Type 1 in Elite Controllers: Lack of Gross Genetic Defects or Common Amino Acid Changes

Todd M. Allen, D. Heckerman, F. Pereyra, 2008, Journal of Virology.

Persistence of attenuated rev genes in a human immunodeficiency virus type 1-infected asymptomatic individual

E. G. Shpaer, B. Walker, M. Hirsch, 1995, Journal of virology.

CD4+ T cells from elite controllers resist HIV-1 infection by selective upregulation of p21.

E. Rosenberg, A. Brass, F. Pereyra, 2011, The Journal of clinical investigation.

Low Levels of Peripheral CD161++CD8+ Mucosal Associated Invariant T (MAIT) Cells Are Found in HIV and HIV/TB Co-Infection

B. Walker, T. Ndung’u, P. Klenerman, 2013, PloS one.

Low Levels of Peripheral CD161++CD8+ Mucosal Associated Invariant T (MAIT) Cells Are Found in HIV and HIV/TB Co-Infection

B. Walker, T. Ndung’u, P. Klenerman, 2013, PloS one.

Frequencies of Circulating Th1-Biased T Follicular Helper Cells in Acute HIV-1 Infection Correlate with the Development of HIV-Specific Antibody Responses and Lower Set Point Viral Load

B. Walker, T. Ndung’u, Z. Ndhlovu, 2018, Journal of Virology.

HIV-1 persistence in CD4+ T cells with stem cell-like properties

E. Rosenberg, F. Pereyra, B. Walker, 2014, Nature Medicine.

Functional impairment of HIV-specific CD8+ T cells precedes aborted spontaneous control of viremia.

Ruchi M. Newman, Todd M. Allen, B. Walker, 2021, Immunity.

Lack of Viral Escape and Defective In Vivo Activation of Human Immunodeficiency Virus Type 1-Specific Cytotoxic T Lymphocytes in Rapidly Progressive Infection

B. Walker, D. Montefiori, Steven Wolinsky, 1999, Journal of Virology.

CD8+ T Cell Breadth and Ex Vivo Virus Inhibition Capacity Distinguish between Viremic Controllers with and without Protective HLA Class I Alleles

B. Walker, T. Ndung’u, J. Prado, 2016, Journal of Virology.

Prolonged Antiretroviral Therapy Preserves HIV-1-Specific CD8 T Cells with Stem Cell-Like Properties

E. Rosenberg, B. Walker, Xu G. Yu, 2015, Journal of Virology.

Lentiviral Vectors Encoding Human Immunodeficiency Virus Type 1 (HIV-1)-Specific T-Cell Receptor Genes Efficiently Convert Peripheral Blood CD8 T Lymphocytes into Cytotoxic T Lymphocytes with Potent In Vitro and In Vivo HIV-1-Specific Inhibitory Activity

B. Walker, C. Brander, K. Sango, 2008, Journal of Virology.

Neutralizing Antibodies Associated with Viremia Control in a Subset of Individuals after Treatment of Acute Human Immunodeficiency Virus Type 1 Infection

E. Rosenberg, B. Walker, D. Montefiori, 2001, Journal of Virology.

Relative Dominance of Epitope-Specific Cytotoxic T-Lymphocyte Responses in Human Immunodeficiency Virus Type 1-Infected Persons with Shared HLA Alleles

E. Rosenberg, M. Altfeld, B. Walker, 2001, Journal of Virology.

Functionally Inert HIV-Specific Cytotoxic T Lymphocytes Do Not Play a Major Role in Chronically Infected Adults and Children

E. Rosenberg, M. Altfeld, B. Walker, 2000, The Journal of experimental medicine.

Identification of Dominant Optimal HLA-B60- and HLA-B61-Restricted Cytotoxic T-Lymphocyte (CTL) Epitopes: Rapid Characterization of CTL Responses by Enzyme-Linked Immunospot Assay

E. Rosenberg, M. Altfeld, B. Walker, 2000, Journal of Virology.

Recognition of two overlapping CTL epitopes in HIV-1 p17 by CTL from a long-term nonprogressing HIV-1-infected individual.

B. Walker, T. Harrer, S. Buchbinder, 1998, Journal of immunology.

IndividualLong-Term Nonprogressing HIV-1-Infected Epitopes in HIV-1 p17 by CTL from a Recognition of Two Overlapping CTL

Kalden, B. Walker, T. Harrer, 1998 .

Systematic Identiflcation of Optimal HIV-1 CTL Epitopes

B. Walker, C. Brander, 1997 .

Long-term culture and fine specificity of human cytotoxic T-lymphocyte clones reactive with human immunodeficiency virus type 1.

R. Young, B. Walker, R. Schooley, 1989, Proceedings of the National Academy of Sciences of the United States of America.

Title: A naturally arising broad and potent CD4-binding site antibody with low somatic mutation 1 Short Title: An HIV-1 bNAb with low somatic mutation

B. Walker, M. Nussenzweig, P. Bjorkman, 2022 .

Coexistence of potent HIV-1 broadly neutralizing antibodies and antibody-sensitive viruses in a viremic controller

B. Walker, D. Burton, Stuart A. Sievers, 2017, Science Translational Medicine.

HIV-1 antibody 3BNC117 suppresses viral rebound in humans during treatment interruption

Nico Pfeifer, Michael S. Seaman, Florian Klein, 2016, Nature.

Functional and genetic analysis of coreceptor usage by dualtropic HIV-1 subtype C isolates.

B. Walker, T. Ndung’u, L. Morris, 2009, Virology.

HLA-B*57 and IFNL4-related polymorphisms are associated with protection against HIV-1 disease progression in controllers.

B. Walker, C. Tural, M. Lichterfeld, 2017, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

CTL Responses of High Functional Avidity and Broad Variant Cross-Reactivity Are Associated with HIV Control

D. Heckerman, F. Pereyra, B. Walker, 2012, PloS one.

Molecular and functional analysis of a conserved CTL epitope in HIV-1 p24 recognized from a long-term nonprogressor: constraints on immune escape associated with targeting a sequence essential for viral replication.

B. Walker, T. Harrer, S. Buchbinder, 1999, Journal of immunology.

Longitudinal analysis of T cell receptor (TCR) gene usage by human immunodeficiency virus 1 envelope-specific cytotoxic T lymphocyte clones reveals a limited TCR repertoire

B. Walker, S. Kalams, A. Trocha, 1994, The Journal of experimental medicine.

The Role of CD4+ T Cell Help and CD40 Ligand in the In Vitro Expansion of HIV-1-Specific Memory Cytotoxic CD8+ T Cell Responses

B. Walker, M. Ostrowski, A. Fauci, 2000, The Journal of Immunology.

Envelope characteristics in individuals who developed neutralizing antibodies targeting different epitopes in HIV-1 subtype C infection.

B. Walker, T. Ndung’u, I. Georgiev, 2020, Virology.

Chapter 20 – AIDS Vaccines

B. Walker, 2016 .

Broad neutralization by a combination of antibodies recognizing the CD4 binding site and a new conformational epitope on the HIV-1 envelope protein

Lynn Morris, Yan Liu, Michael S. Seaman, 2012, The Journal of experimental medicine.

Continuous Viral Escape and Selection by Autologous Neutralizing Antibodies in Drug-Naïve Human Immunodeficiency Virus Controllers

F. Pereyra, T. Miura, B. Walker, 2008, Journal of Virology.

Toward an AIDS Vaccine

Dennis R. Burton, B. Walker, D. Burton, 2008, Science.

Loss of HIV-1-specific T-cell responses associated with very rapid HIV-1 disease progression.

Todd M. Allen, H. Jessen, M. Altfeld, 2007, AIDS.

Signatures of immune selection in intact and defective proviruses distinguish HIV-1 elite controllers

E. Rosenberg, B. Walker, M. Peluso, 2021, Science Translational Medicine.

Nonprogressing HIV-infected children share fundamental immunological features of nonpathogenic SIV infection

B. Walker, T. Ndung’u, P. Goulder, 2016, Science Translational Medicine.

An HLA-I signature favouring KIR-educated Natural Killer cells mediates immune control of HIV in children and contrasts with the HLA-B-restricted CD8+ T-cell-mediated immune control in adults

B. Walker, T. Ndung’u, J. Martinez-Picado, 2021, PLoS pathogens.

Acute HIV infection among patients tested for mononucleosis.

B. Walker, A. Caliendo, E. Rosenberg, 1999, The New England journal of medicine.

Augmentation of HIV-1-specific T helper cell responses in chronic HIV-1 infection by therapeutic immunization

E. Rosenberg, B. Walker, M. Addo, 2003, AIDS.

High‐resolution definition of humoral immune response correlates of effective immunity against HIV

Karen G. Dowell, B. Walker, C. Bailey-Kellogg, 2018, Molecular systems biology.

Correction: Antigen-Specific Antibody Glycosylation Is Regulated via Vaccination

B. Walker, H. Schuitemaker, G. Alter, 2016, PLoS pathogens.

Antigen-Specific Antibody Glycosylation Is Regulated via Vaccination

B. Walker, H. Schuitemaker, G. Alter, 2016, PLoS pathogens.

Polyfunctional HIV-Specific Antibody Responses Are Associated with Spontaneous HIV Control

Karen G. Dowell, B. Walker, C. Bailey-Kellogg, 2016, PLoS pathogens.

Nef-Specific CD8+ T Cell Responses Contribute to HIV-1 Immune Control

D. Heckerman, B. Walker, T. Ndung’u, 2013, PloS one.

Full-Breadth Analysis of CD8+ T-Cell Responses in Acute Hepatitis C Virus Infection and Early Therapy

Bin Li, Todd M. Allen, B. Walker, 2005, Journal of Virology.

Comprehensive Analysis of CD8+-T-Cell Responses against Hepatitis C Virus Reveals Multiple Unpredicted Specificities

B. Walker, P. Klenerman, G. Lauer, 2002, Journal of Virology.

Human Immunodeficiency Virus Type 1-Hepatitis C Virus Coinfection: Intraindividual Comparison of Cellular Immune Responses against Two Persistent Viruses

E. Rosenberg, B. Walker, P. Klenerman, 2002, Journal of Virology.

Ligand-Independent Exhaustion of Killer Immunoglobulin-Like Receptor-Positive CD8+ T Cells in Human Immunodeficiency Virus Type 1 Infection

F. Pereyra, M. Altfeld, B. Walker, 2008, Journal of Virology.

Ligand-Independent Exhaustion of Killer Immunoglobulin-Like Receptor-Positive CD8 (cid:1) T Cells in Human Immunodeﬁciency Virus Type 1 Infection (cid:1)

F. Pereyra, M. Altfeld, B. Walker, 2008 .

Differential Immunodominance Hierarchy of CD8+ T-Cell Responses in HLA-B*27:05- and -B*27:02-Mediated Control of HIV-1 Infection

M. Carrington, B. Walker, M. John, 2017, Journal of Virology.

Differential Immunodominance Hierarchy of CD8+ T-Cell Responses in HLA-B*27:05- and -B*27:02-Mediated Control of HIV-1 Infection

M. Carrington, B. Walker, M. John, 2017, Journal of Virology.

HIGH-FREQUENCY failure of combination antiretroviral therapy in paediatric HIV infection is associated with unmet maternal needs causing maternal NON-ADHERENCE

B. Walker, T. Ndung’u, D. Bonsall, 2020, EClinicalMedicine.

Lessons to be Learned from Natural Control of HIV – Future Directions, Therapeutic, and Preventive Implications

B. Walker, D. Shasha, 2013, Front. Immunol..

Long noncoding RNA MIR4435-2HG enhances metabolic function of myeloid dendritic cells from HIV-1 elite controllers.

B. Walker, Xu G. Yu, M. Lichterfeld, 2021, The Journal of clinical investigation.

Short communication: CD8(+) T cell polyfunctionality profiles in progressive and nonprogressive pediatric HIV type 1 infection.

M. Altfeld, B. Walker, T. Ndung’u, 2011, AIDS research and human retroviruses.

Programmed death-1 as a factor in immune exhaustion and activation in HIV infection

B. Walker, D. Kaufmann, 2008, Current opinion in HIV and AIDS.

Prolonged viral suppression with anti-HIV-1 antibody therapy

B. Walker, M. Nussenzweig, T. Chun, 2022, Nature.

Immunodominant HIV-1 Cd4+ T Cell Epitopes in Chronic Untreated Clade C HIV-1 Infection

B. Walker, D. Kaufmann, P. Goulder, 2009, PloS one.

CXCL13 is a plasma biomarker of germinal center activity

Mark M. Davis, B. Walker, B. Pulendran, 2016, Proceedings of the National Academy of Sciences.

A cell-intrinsic inhibitor of HIV-1 reverse transcription in CD4(+) T cells from elite controllers.

F. Pereyra, B. Walker, Xu G. Yu, 2014, Cell host & microbe.

Statistical Resolution of Ambiguous HLA Typing Data

David Heckerman, Jennifer Listgarten, Carl Myers Kadie, 2008, PLoS Comput. Biol..

Fine-mapping classical HLA variation associated with durable host control of HIV-1 infection in African Americans.

D. Heckerman, N. Lennon, F. Pereyra, 2012, Human molecular genetics.

Leukocyte Immunoglobulin-Like Receptors Maintain Unique Antigen-Presenting Properties of Circulating Myeloid Dendritic Cells in HIV-1-Infected Elite Controllers

F. Pereyra, B. Walker, Xu G. Yu, 2010, Journal of Virology.

The −1030/−862-linked TNF promoter single-nucleotide polymorphisms are associated with the inability to control HIV-1 viremia

B. Walker, E. Vittinghoff, Steven Wolinsky, 2003, Immunogenetics.

Induction of Robust Cellular and Humoral Virus-Specific Adaptive Immune Responses in Human Immunodeficiency Virus-Infected Humanized BLT Mice

Andrew D. Luster, Gordon J. Freeman, Christian Brander, 2009, Journal of Virology.

T-Cell Receptor (TCR) Clonotype-Specific Differences in Inhibitory Activity of HIV-1 Cytotoxic T-Cell Clones Is Not Mediated by TCR Alone

Mark M. Davis, B. Walker, E. Newell, 2017, Journal of Virology.

Increased HIV-specific CD8+ T-cell cytotoxic potential in HIV elite controllers is associated with T-bet expression.

F. Pereyra, B. Walker, R. Kaul, 2011, Blood.

HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes

David Heckerman, Jonathan M. Carlson, Charles E. DeZiel, 2014, Journal of Virology.

Impact of intrapeptide epitope location on CD8 T cell recognition: implications for design of overlapping peptide panels

M. Altfeld, B. Walker, C. Brander, 2004, AIDS.

Viral control in chronic HIV-1 subtype C infection is associated with enrichment of p24 IgG1 with Fc effector activity

B. Walker, T. Ndung’u, P. Goulder, 2018, AIDS.

The Fitness Landscape of HIV-1 Gag: Advanced Modeling Approaches and Validation of Model Predictions by In Vitro Testing

John P. Barton, Andrew L. Ferguson, Bruce D. Walker, 2014, PLoS Comput. Biol..

Gag-Specific Cellular Immunity Determines In Vitro Viral Inhibition and In Vivo Virologic Control following Simian Immunodeficiency Virus Challenges of Vaccinated Rhesus Monkeys

B. Walker, N. Michael, D. Barouch, 2012, Journal of Virology.

Gag-Specific Cellular Immunity Determines In Vitro Viral Inhibition and In 2

B. Walker, N. Michael, D. Barouch, 2012 .

Increased detection of HIV-specific T cell responses by combination of central sequences with comparable immunogenicity

Todd M. Allen, B. Walker, D. Nickle, 2008, AIDS.

THE HIV VACCINE PROBLEM : WHY HAVE PAST APPROACHES TO DEVELOP AN HIV VACCINE FAILED ?

Walker, A. Godzik, B. Walker, 2022 .

Comprehensive Analysis of Human Immunodeficiency Virus Type 1-Specific CD4 Responses Reveals Marked Immunodominance of gag and nef and the Presence of Broadly Recognized Peptides

E. Rosenberg, M. Altfeld, B. Walker, 2004, Journal of Virology.

Circulating CXCR5+CXCR3+PD-1lo Tfh-like cells in HIV-1 controllers with neutralizing antibody breadth.

B. Walker, Kellie E Kolb, A. Shalek, 2017, JCI insight.

Circulating CXCR5[superscript +]CXCR3[superscript +]PD-1[superscript lo] Tfh-like cells in HIV-1 controllers with neutralizing antibody breadth

B. Walker, Kellie E Kolb, A. Shalek, 2017 .

CD8 lymphocytes mitigate HIV-1 persistence in lymph node follicular helper T cells during hyperacute-treated infection

Jaclyn K. Mann, B. Walker, T. Ndung’u, 2022, Nature Communications.

Elite Controllers with Low to Absent Effector CD8+ T Cell Responses Maintain Highly Functional, Broadly Directed Central Memory Responses

F. Pereyra, B. Walker, Z. Ndhlovu, 2012, Journal of Virology.

HIV-Specific CD4 T Cell Responses to Different Viral Proteins Have Discordant Associations with Viral Load and Clinical Outcome

D. Heckerman, F. Pereyra, B. Walker, 2011, Journal of Virology.

Temporal effect of HLA-B*57 on viral control during primary HIV-1 infection

Todd M. Allen, E. Rosenberg, H. Jessen, 2013, Retrovirology.

A New Glycan-Dependent CD4-Binding Site Neutralizing Antibody Exerts Pressure on HIV-1 In Vivo

B. Walker, John P. Moore, Stuart A. Sievers, 2015, PLoS pathogens.

Motif Inference Reveals Optimal CTL Epitopes Presented by HLA Class I Alleles Highly Prevalent in Southern Africa1

B. Walker, C. Brander, P. Goulder, 2006, The Journal of Immunology.

Accelerating Next-Generation Vaccine Development for Global Disease Prevention

Philip R. Johnson, B. Walker, D. Burton, 2013, Science.

Expansion of HIV-specific CD4+ and CD8+ T cells by dendritic cells transfected with mRNA encoding cytoplasm- or lysosome-targeted Nef.

E. Rosenberg, B. Walker, E. Gilboa, 2006, Blood.

Overlapping epitopes in human immunodeficiency virus type 1 gp120 presented by HLA A, B, and C molecules: effects of viral variation on cytotoxic T-lymphocyte recognition

B. Walker, Steven Wolinsky, C. Wilson, 1997, Journal of virology.

HIV Patients Developing Primary CNS Lymphoma Lack EBV-Specific CD4+ T Cell Function Irrespective of Absolute CD4+ T Cell Counts

B. Walker, H. Günthard, C. Brander, 2007, PLoS medicine.

Telomerase activity of HIV-1-specific CD8+ T cells: constitutive up-regulation in controllers and selective increase by blockade of PD ligand 1 in progressors.

E. Rosenberg, F. Pereyra, B. Walker, 2008, Blood.

Frequent and Strong Antibody-Mediated Natural Killer Cell Activation in Response to HIV-1 Env in Individuals with Chronic HIV-1 Infection

Todd M. Allen, E. Rosenberg, F. Pereyra, 2012, Journal of Virology.

Spontaneous resolution of chronic hepatitis C virus disease after withdrawal of immunosuppression.

B. Walker, G. Lauer, R. Chung, 2003, Gastroenterology.

A Possible Sterilizing Cure of HIV-1 Infection Without Stem Cell Transplantation

R. Siliciano, B. Walker, Xu G. Yu, 2021, Annals of Internal Medicine.

Proliferative Capacity of Epitope-Specific CD8 T-Cell Responses Is Inversely Related to Viral Load in Chronic Human Immunodeficiency Virus Type 1 Infection

B. Walker, P. Klenerman, P. Goulder, 2006, Journal of Virology.

Lack of Detectable HIV-1–Specific CD8+ T Cell Responses in Zambian HIV-1–Exposed Seronegative Partners of HIV-1–Positive Individuals

M. Altfeld, B. Walker, M. Addo, 2011, The Journal of infectious diseases.

Differential regulation of toll-like receptor pathways in acute and chronic HIV-1 infection

Todd M. Allen, E. Rosenberg, F. Pereyra, 2012, AIDS.

Greater viral rebound and reduced time to resume antiretroviral therapy after therapeutic immunization with the ALVAC-HIV vaccine (vCP1452)

B. Walker, V. Calvez, B. Clotet, 2008, AIDS.

Erratum: HIV-1 superinfection despite broad CD8 + T-cell responses containing replication of the primary virus (Nature (2002) 420 (434-439))

Todd M. Allen, E. Rosenberg, M. Altfeld, 2003 .

Elite controller CD8+ T cells exhibit comparable viral inhibition capacity, but better sustained effector properties compared to chronic progressors

B. Walker, F. Porichis, D. Shasha, 2016, Journal of leukocyte biology.

Antiviral CD8+ T Cells Restricted by Human Leukocyte Antigen Class II Exist during Natural HIV Infection and Exhibit Clonal Expansion

Todd M. Allen, B. Walker, S. Kazer, 2016, Immunity.

Naturally processed viral peptides recognized by cytotoxic T lymphocytes on cells chronically infected by human immunodeficiency virus type 1

R. Young, B. Walker, R. Johnson, 1994, The Journal of experimental medicine.

and reversibly inhibits virus-specific T cells IL-10 is up-regulated in multiple cell types during viremic HIV infection

H. Jessen, B. Walker, D. Kwon, 2012 .

Quantitative Assays for Virus Detection

B. Walker, D. Ho, V. Johnson, 1990 .

Resistance of HIV-infected macrophages to CD8 T lymphocyte-mediated killing drives immune activation

J. Lieberman, B. Walker, K. Clayton, 2018, Nature Immunology.

Antagonism of HIV-specific CD4+ T cells by C-terminal truncation of a minimum epitope.

B. Walker, J. Stone, H. Moffett, 2006, Molecular immunology.

Clonal expansion of genome-intact HIV-1 in functionally polarized Th1 CD4+ T cells

E. Rosenberg, B. Walker, T. Ndung’u, 2017, The Journal of clinical investigation.

Epitope convergence of broadly HIV-1 neutralizing IgA and IgG antibody lineages in a viremic controller

B. Walker, F. Rey, J. Dimitrov, 2022, The Journal of experimental medicine.

IgG subclass profiles in infected HIV type 1 controllers and chronic progressors and in uninfected recipients of Env vaccines.

F. Pereyra, B. Walker, John P. Moore, 2010, AIDS research and human retroviruses.

Follicular Dendritic Cells Retain Infectious HIV in Cycling Endosomes

M. Altfeld, B. Walker, D. Kaufmann, 2015, PLoS pathogens.

T-cell responses targeting HIV Nef uniquely correlate with infected cell frequencies after long-term antiretroviral therapy

B. Walker, C. Kovacs, J. Mellors, 2017, PLoS pathogens.

Broad diversity of neutralizing antibodies isolated from memory B cells in HIV-infected individuals

Richard T. Wyatt, Michael S. Seaman, John R. Mascola, 2009, Nature.

Detection of polyfunctional Mycobacterium tuberculosis-specific T cells and association with viral load in HIV-1-infected persons.

B. Walker, P. Klenerman, Z. Mncube, 2008, The Journal of infectious diseases.

Phenotypic signatures of immune selection in HIV-1 reservoir cells

E. Rosenberg, B. Walker, Xu G. Yu, 2023, Nature.

CMV, MHC-E, and the quest for an unconventional AIDS vaccine

B. Walker, 2021, Science Immunology.

Histone Deacetylase Inhibitors Impair the Elimination of HIV-Infected Cells by Cytotoxic T-Lymphocytes

D. Irvine, B. Walker, A. Trocha, 2014, PLoS pathogens.

Dysfunctional HIV-specific CD8+ T cell proliferation is associated with increased caspase-8 activity and mediated by necroptosis.

A. Brass, B. Walker, E. Wherry, 2014, Immunity.

Immunotherapy for AIDS virus infections: Cautious optimism for cell-based vaccine

B. Walker, N. Bhardwaj, 2003, Nature Medicine.

Inhibition of Human Immunodeficiency Virus Type 1 Replication in Primary CD4+ T Lymphocytes, Monocytes, and Dendritic Cells by Cytotoxic T Lymphocytes

B. Walker, O. Yang, S. Kalams, 2000, Journal of Virology.

Inhibition of Human Immunodeficiency Virus Type 1 Replication in Primary CD 4 1 T Lymphocytes , Monocytes , and Dendritic Cells by Cytotoxic T Lymphocytes

B. Walker, O. Yang, S. Kalams, 2000 .

T cell receptor usage and fine specificity of human immunodeficiency virus 1-specific cytotoxic T lymphocyte clones: analysis of quasispecies recognition reveals a dominant response directed against a minor in vivo variant

W. Blattner, B. Walker, T. Harrer, 1996, The Journal of experimental medicine.

Transcriptional down-regulation of ccr5 in a subset of HIV+ controllers and their family members

B. Walker, D. Rimland, V. Marconi, 2019, eLife.

Preserved function of regulatory T cells in chronic HIV-1 infection despite decreased numbers in blood and tissue.

F. Pereyra, M. Altfeld, B. Walker, 2012, The Journal of infectious diseases.

Type 2 Bias of T cells expanded from the blood of melanoma patients switched to type 1 by IL-12p70 mRNA-transfected dendritic cells.

B. Walker, S. Adams, G. Alter, 2008, Cancer research.

HIV Molecular Immunology 2014

B. Walker, B. Korber, B. Haynes, 2015 .

An optimal viral peptide recognized by CD8+ T cells binds very tightly to the restricting class I major histocompatibility complex protein on intact cells but not to the purified class I protein.

B. Walker, H. Eisen, B D Walker, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Cytotoxic CD8+ T lymphocytes reactive with human immunodeficiency virus-1 produce granulocyte/macrophage colony-stimulating factor and variable amounts of interleukins 2, 3, and 4 following stimulation with the cognate epitope.

B. Walker, S. Kalams, R. Johnson, 1995, Clinical immunology and immunopathology.

T cell receptor cross-recognition of an HIV-1 CD8+ T cell epitope presented by closely related alleles from the HLA-A3 superfamily.

E. Rosenberg, M. Altfeld, B. Walker, 2006, International immunology.

Degenerate and promiscuous recognition by CTL of peptides presented by the MHC class I A3-like superfamily: implications for vaccine development.

B. Walker, J. Sidney, A. Sette, 1997, Journal of immunology.

HLA-Specific Intracellular Epitope Processing Shapes an Immunodominance Pattern for HLA-B*57 That Is Distinct from HLA-B*58:01

Greg J. Towers, Søren Buus, Mikkel Harndahl, 2013, Journal of Virology.

HIV-1 infection does not induce tumor necrosis factor-alpha or interferon-beta gene transcription.

B. Walker, R. Schooley, A. Goldfeld, 1991, Journal of acquired immune deficiency syndromes.

Recognition of the highly conserved YMDD region in the human immunodeficiency virus type 1 reverse transcriptase by HLA-A2-restricted cytotoxic T lymphocytes from an asymptomatic long-term nonprogressor.

B. Walker, T. Harrer, S. Buchbinder, 1996, The Journal of infectious diseases.

Identification of type-specific cytotoxic T lymphocyte responses to homologous viral proteins in laboratory workers accidentally infected with HIV-1.

W. Blattner, B. Walker, S. Kalams, 1997, The Journal of clinical investigation.

Cytotoxic T lymphocytes in human immunodeficiency virus infection: responses to structural proteins.

B. Walker, R. Johnson, R. Johnson, 1994, Current topics in microbiology and immunology.

Lysis of HIV-1-infected cells and inhibition of viral replication by universal receptor T cells.

B. Walker, O. Yang, S. Kalams, 1997, Proceedings of the National Academy of Sciences of the United States of America.

High Avidity CD8+ T Cells Efficiently Eliminate Motile HIV-Infected Targets and Execute a Locally Focused Program of Anti-Viral Function

Talitha L Forcier, D. Irvine, B. Walker, 2014, PloS one.

HIV-1 gag-specific cytotoxic T lymphocytes recognize multiple highly conserved epitopes. Fine specificity of the gag-specific response defined by using unstimulated peripheral blood mononuclear cells and cloned effector cells.

B. Walker, A. Trocha, R. Johnson, 1991, Journal of immunology.

Pathways in HIV Infection and the Potential PD-1 and CTLA-4 Inhibitory Cosignaling

B. Walker, D. Kaufmann, 2009 .

Epitopes du virus de l'hepatite c

B. Walker, G. Lauer, K. Ouchi, 2003 .

HIV-1 Vpu represents a minor target for cytotoxic T lymphocytes in HIV-1-infection.

E. Rosenberg, M. Altfeld, B. Walker, 2002, AIDS.

Characterization of the HIV-1-Specific T-Helper Cell Response

B. Walker, 2001 .

Two double-blinded, randomized, comparative trials of 4 human immunodeficiency virus type 1 (HIV-1) envelope vaccines in HIV-1-infected individuals across a spectrum of disease severity: AIDS Clinical Trials Groups 209 and 214.

B. Walker, R. Schooley, M. Hirsch, 2000, Journal of Infectious Diseases.

Immune control of HIV-1 replication.

B. Walker, O. Yang, E. Rosenberg, 1998, Advances in experimental medicine and biology.

Important contribution of p15 Gag-specific responses to the total Gag-specific CTL responses

E. Rosenberg, M. Altfeld, B. Walker, 2002, AIDS.

Anti-HIV cellular immunity: recent advances towards vaccine design.

B. Walker, S. Rowland-Jones, A. McMichael, 1999, AIDS.

HIV-1-specific cytotoxic T lymphocyte response in healthy, long-term nonprogressing seropositive persons.

B. Walker, T. Harrer, S. Buchbinder, 1994, AIDS research and human retroviruses.

Decreased CXCR3+ CD8 T Cells in Advanced Human Immunodeficiency Virus Infection Suggest that a Homing Defect Contributes to Cytotoxic T-Lymphocyte Dysfunction

B. Walker, C. Brander, N. Frahm, 2007, Journal of Virology.

Migration ofAntigen-Specific T Cells Away from CXCR4-Binding Human ImmunodeficiencyVirus Type 1gp120

B. Walker, R. Wyatt, A. Trocha, 2004, Journal of Virology.

Immunization of HIV-1-Infected Persons With Autologous Dendritic Cells Transfected With mRNA Encoding HIV-1 Gag and Nef: Results of a Randomized, Placebo-Controlled Clinical Trial

B. Walker, D. Kaufmann, T. Flynn, 2016, Journal of acquired immune deficiency syndromes.

Preferential CTL targeting of Gag is associated with relative viral control in long-term surviving HIV-1 infected former plasma donors from China

M. Altfeld, B. Walker, Xu G. Yu, 2012, Cell Research.

Detection of HIV type 1 gag-specific CD4(+) T cell responses in acutely infected infants.

B. Walker, W. Mphatswe, P. Goulder, 2008, AIDS research and human retroviruses.

A method for identification of HIV gp140 binding memory B cells in human blood.

F. Pereyra, B. Walker, J. Mascola, 2009, Journal of immunological methods.

Cytotoxic T lymphocytes and HIV-1 related neurologic disorders.

B. Walker, S. Kalams, 1995, Current topics in microbiology and immunology.

Retroviral immunology : immune response and restoration

B. Walker, G. Pantaleo, 2001 .

Innate lymphoid cells and COVID-19 severity in SARS-CoV-2 infection

B. Walker, Xu G. Yu, M. Betts, 2022, eLife.

T cell reactivity to the SARS-CoV-2 Omicron variant is preserved in most but not all individuals

B. Walker, V. Naranbhai, A. Balazs, 2022, Cell.

Immunological Fingerprints of Controllers Developing Neutralizing HIV-1 Antibodies

B. Walker, Kellie E Kolb, A. Shalek, 2020, Cell reports.

In Vitro Priming Recapitulates In Vivo HIV-1 Specific T Cell Responses, Revealing Rapid Loss of Virus Reactive CD4+ T Cells in Acute HIV-1 Infection

E. Rosenberg, B. Walker, D. Kaufmann, 2009, PloS one.

The AMP Trials - A Glass Half Full.

B. Walker, 2021, The New England journal of medicine.

Progressive reversion of human immunodeficiency virus type 1 resistance mutations in vivo after transmission of a multiply drug-resistant virus.

E. Rosenberg, B. Walker, M. Hirsch, 2003, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

The Duffy antigen receptor for chemokines null promoter variant does not influence HIV-1 acquisition or disease progression.

K. Shianna, D. Ge, D. Goldstein, 2009, Cell host & microbe.

Early proliferation of CCR5(+) CD38(+++) antigen-specific CD4(+) Th1 effector cells during primary HIV-1 infection.

E. Rosenberg, B. Walker, J. Kaldor, 2005, Blood.

The paradox of incomplete CD4+ cell count restoration despite successful antiretroviral treatment and the need to start highly active antiretroviral therapy early.

B. Walker, B. Julg, 2009, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Therapeutic vaccines against HIV need international partnerships

B. Walker, C. Katlama, B. Autran, 2003, Nature Reviews Immunology.

Persistent HIV-1-specific CTL clonal expansion despite high viral burden post in utero HIV-1 infection.

B. Walker, O. Yang, C. Brander, 1999, Journal of immunology.

Enhanced Inhibition of Human Immunodeficiency Virus Type 1 by Met-Stromal-Derived Factor 1β Correlates with Down-Modulation of CXCR4

B. Walker, O. Yang, M. Dziejman, 1999, Journal of Virology.

Epigenetic regulation of telomerase expression in HIV-1-specific CD8+ T cells

E. Rosenberg, F. Pereyra, B. Walker, 2010, AIDS.

Developing whole mycobacteria cell vaccines for tuberculosis: Workshop proceedings, Max Planck Institute for Infection Biology, Berlin, Germany, July 9, 2014.

Richard G. White, B. Walker, S. Kaufmann, 2015, Vaccine.

Pervasive Influence of Hepatitis C Virus on the Phenotype of Antiviral CD8+ T Cells1

B. Walker, P. Klenerman, G. Lauer, 2004, The Journal of Immunology.

Engineering modular intracellular protein sensor-actuator devices benefits you. Your matters

Liliana Wroblewska, B. Walker, Jin Huh, 2018 .

Programming CMV for vaccine vector design

B. Walker, S. Ranasinghe, 2013, Nature Biotechnology.

Metabolic pathway activation distinguishes transcriptional signatures of CD8+ T cells from HIV-1 elite controllers

B. Walker, Zhengyu Ouyang, M. Lichterfeld, 2018, AIDS.

Plasma CXCL13 but Not B Cell Frequencies in Acute HIV Infection Predicts Emergence of Cross-Neutralizing Antibodies

B. Walker, T. Ndung’u, L. Morris, 2017, Front. Immunol..

The Control of HIV After Antiretroviral Medication Pause (CHAMP) Study: Posttreatment Controllers Identified From 14 Clinical Studies

B. Walker, R. Schooley, S. Little, 2018, The Journal of infectious diseases.

CellsPD-1 Expression in Virus-Specific CD8 T Reinforces a Poised Epigenetic Program for Cutting Edge: Prolonged Exposure to HIV

T. Miura, B. Walker, J. Sidney, 2013 .

Regulatory T cell frequencies do not correlate with breadth or magnitude of HIV-1-specific T cell responses.

F. Pereyra, M. Altfeld, B. Walker, 2012, AIDS research and human retroviruses.

Association between the cytokine storm, immune cell dynamics, and viral replicative capacity in hyperacute HIV infection

Jaclyn K. Mann, B. Walker, T. Ndung’u, 2020, BMC Medicine.

Virus-driven Inflammation Is Associated With the Development of bNAbs in Spontaneous Controllers of HIV

D. Lauffenburger, F. Pereyra, B. Walker, 2017, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

HIV Molecular Immunology 2015

B. Walker, B. Korber, B. Haynes, 2016 .

Antiviral Activity of ANA773, an Oral Inducer of Endogenous Interferons that Acts Via TLR7, in Chronic Hepatitis C Patients

B. Walker, S. Akira, J. Kaldor, 2011 .

A Leucine Zipper Dimerization Strategy to Generate Soluble T Cell Receptors Using the Escherichia coli Expression System

B. Walker, A. Piechocka-Trocha, A. Zhang, 2022, Cells.

Integrated single-cell analysis of multicellular immune dynamics during hyperacute HIV-1 infection

J. C. Love, B. Walker, T. Ndung’u, 2020, Nature Network Boston.

Increased frequencies of CD8+CD57+ T cells are associated with antibody neutralization breadth against HIV in viraemic controllers

B. Walker, L. Chibnik, E. Scully, 2016, Journal of the International AIDS Society.

HIV-1 Antibody Neutralization Breadth Is Associated with Enhanced HIV-Specific CD4+ T Cell Responses

M. Carrington, B. Walker, D. Kaufmann, 2015, Journal of Virology.

Antiretroviral therapy in early HIV infection.

B. Walker, M. Hirsch, 2013, The New England journal of medicine.

Hypermethylation at the CXCR5 gene locus limits trafficking potential of CD8+ T cells into B-cell follicles during HIV-1 infection

B. Walker, T. Ndung’u, Z. Ndhlovu, 2022, Blood advances.

CD 4 + T cells from elite controllers resist HIV-1 infection by selective upregulation of p 21

E. Rosenberg, A. Brass, F. Pereyra, 2018 .

Curing HIV will require eliminating the reservoir of integrated, replication-competent proviruses

Richard H. Liang, B. Walker, A. Trocha, 2021 .

Immune reconstitution: is there a potential role for Filgrastim (r-metHuG-CSF).

B. Walker, 1999, Journal of hematotherapy & stem cell research.

Investigation of primary human immunodeficiency virus infection in patients who test positive for heterophile antibody.

E. Rosenberg, B. Walker, R. Walensky, 2001, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

CD8(+) T Cells and cART: A Dynamic Duo?

B. Walker, G. Gaiha, 2016, Immunity.

P09-19 LB. CTL escape mutations in gag epitopes restricted by protective HLA class I alleles cause substantial reductions in viral replication capacity

M. Altfeld, B. Walker, H. Streeck, 2009, Retrovirology.

High Level of PD-1 Expression on Hepatitis C Virus (HCV)-Specific CD8+ and CD4+ T Cells during Acute HCV Infection, Irrespective of Clinical Outcome

Todd M. Allen, B. Walker, P. Klenerman, 2011, Journal of Virology.

Moving ahead an HIV vaccine: Use both arms to beat HIV

B. Walker, R. Ahmed, S. Plotkin, 2011, Nature Medicine.

Is antiretroviral treatment of primary HIV infection clinically justified on the basis of current evidence?

E. Rosenberg, B. Walker, J. Kaldor, 2004, AIDS.

During HIV-1 Infection Vpr Is Preferentially Targeted by CTL Rosenberg and

M. Altfeld, B. Walker, C. Brander, 2001 .

ligand 1 in progressors up-regulation in controllers and selective increase by blockade of PD T cells : constitutive + specific CD 8 − Telomerase activity of HIV-1

E. Rosenberg, F. Pereyra, B. Walker, 2008 .

A Microchip CD 4 Counting Method for HIV Monitoring in Resource-Poor Settings

Sanghamitra Mohanty, John T. McDevitt, Nicolaos Christodoulides, 2005 .

Is an HIV Vaccine Possible?

B. Walker, M. McElrath, 2012, Journal of acquired immune deficiency syndromes.

HIV versus the immune system: another apparent victory for the virus.

B. Walker, N. Letvin, 2001, The Journal of clinical investigation.

Antiretroviral resistance during successful therapy of HIV type 1 infection.

E. Rosenberg, R. Siliciano, B. Walker, 2000, Proceedings of the National Academy of Sciences of the United States of America.

CCR5AS lncRNA variation differentially regulates CCR5, influencing HIV disease outcome

J. Goedert, M. Carrington, B. Walker, 2019, Nature Immunology.

HIV type 1-specific helper T cells: a critical host defense.

E. Rosenberg, B. Walker, B. Walker, 1998, AIDS research and human retroviruses.

HIV Molecular Immunology 2001

B. Walker, B. Korber, B. Haynes, 2001 .

Innate Lymphoid Cells Are Depleted in HIV Infection

B. Walker, T. Ndung’u, P. Goulder, 2014 .

Engineering modular intracellular protein sensor-actuator devices

Jacob Beal, Ron Weiss, Liliana Wroblewska, 2018, Nature Communications.

Differential Immunodominance Hierarchy of CD8 (cid:2) T-Cell Responses in HLA-B * 27:05- and -B * 27:02-Mediated Control of HIV-1 Infection

B. Walker, M. John, S. Mallal, 2018 .

Differential Immunodominance Hierarchy of CD8 (cid:2) T-Cell Responses in HLA-B * 27:05- and -B * 27:02-Mediated Control of HIV-1 Infection

B. Walker, M. John, S. Mallal, 2018 .

Approaches to the development of broadly protective HIV vaccines: challenges posed by the genetic, biological and antigenic variability of HIV-1: Report* from a meeting of the WHO-UNAIDS Vaccine Advisory Committee** Geneva, 21–23 February 2000

Guido Ferrari, N. Nathanson, Donald S. Burke, 2001, AIDS.

Comparison of CyTOF assays across sites: Results of a six-center pilot study

Lisa E. Wagar, Mark M. Davis, B. Walker, 2017, Journal of immunological methods.

Extrafollicular IgD−CD27−CXCR5−CD11c− DN3 B cells infiltrate inflamed tissues in autoimmune fibrosis and in severe COVID-19

B. Walker, M. Lichterfeld, S. Pillai, 2023, Cell reports.

Gag-specific cellular immunity determines in vitro viral inhibition and in vivo virologic control following SIV challenges of vaccinated monkeys

B. Walker, N. Michael, D. Barouch, 2012, Retrovirology.

IL-10 is up-regulated in multiple cell types during viremic HIV infection and reversibly inhibits virus-specific T cells.

H. Jessen, F. Pereyra, B. Walker, 2009, Blood.

Molecular basis of differential HLA class I-restricted T cell recognition of a highly networked HIV peptide

B. Walker, T. Huynh, R. Zhou, 2023, Nature communications.

Polymorphisms of large effect explain the majority of the host genetic contribution to variation of HIV-1 virus load

D. Goldstein, J. Goedert, M. Carrington, 2015, Proceedings of the National Academy of Sciences.

HLA-A*68: 02-restricted Gag-specific cytotoxic T lymphocyte responses can drive selection pressure on HIV but are subdominant and ineffective

B. Walker, T. Ndung’u, S. Buus, 2013, AIDS.

Central Role of Reverting Mutations in HLA Associations with Human Immunodeficiency Virus Set Point

D. Heckerman, B. Walker, C. Kadie, 2008, Journal of Virology.

Elite Controllers with Low to Absent Effector CD8+ T Cell Responses Maintain Highly Functional, Broadly Directed Central Memory Responses

F. Pereyra, B. Walker, Z. Ndhlovu, 2012, Journal of Virology.

Analysis of Successful Immune Responses in Persons Infected with Hepatitis C Virus

B. Walker, P. Klenerman, R. Chapman, 2000, The Journal of experimental medicine.

Viraemia suppressed in HIV-1-infected humans by broadly neutralizing antibody 3BNC117

B. Walker, M. Nussenzweig, A. West, 2015, Nature.

Extrafollicular IgD−CD27−CXCR5−CD11c− DN3 B cells infiltrate inflamed tissues in autoimmune fibrosis and in severe COVID-19

B. Walker, M. Lichterfeld, S. Pillai, 2023, Cell Reports.

CD161 expression on hepatitis C virus–specific CD8+ T cells suggests a distinct pathway of T cell differentiation

B. Walker, P. Klenerman, G. Lauer, 2008, Hepatology.

Possession of HLA class II DRB1*1303 associates with reduced viral loads in chronic HIV-1 clade C and B infection.

M. Carrington, B. Walker, Y. Qi, 2011, The Journal of infectious diseases.

Africa-specific human genetic variation near CHD1L associates with HIV-1 load

Andrew R. Bassett, J. Goedert, A. Trkola, 2023, Nature.

The Duffy antigen receptor for chemokines null promoter variant does not influence HIV-1 acquisition or disease progression.

K. Shianna, D. Ge, M. Carrington, 2009, Cell host & microbe.

Epitope specificity of MHC restricted cytotoxic T lymphocytes induced by candidate HIV-1 vaccine.

R. Siliciano, B. Walker, A. Trocha, 1994, AIDS research and human retroviruses.

Inter-clade cross-reactivity of HIV-1-specific T cell responses in human immunodeficiency virus type 1 infection in China.

M. Altfeld, B. Walker, Y. Zhuang, 2007, Current HIV research.

Resistance of HIV-infected macrophages to CD8 T lymphocyte-mediated killing drives immune activation

J. Lieberman, B. Walker, K. Clayton, 2018, Nature Immunology.

A method for identification of HIV gp140 binding memory B cells in human blood.

F. Pereyra, B. Walker, J. Mascola, 2009, Journal of immunological methods.

HLA-C levels impact natural killer cell subset distribution and function.

M. Altfeld, M. Carrington, B. Walker, 2016, Human immunology.

Naturally occurring dominant resistance mutations to hepatitis C virus protease and polymerase inhibitors in treatment‐naïve patients

Todd M. Allen, D. Heckerman, N. Lennon, 2008, Hepatology.

Uncommon Pathways of Immune Escape Attenuate HIV-1 Integrase Replication Capacity

D. Heckerman, E. Rosenberg, H. Jessen, 2012, Journal of Virology.

Early Selection in Gag by Protective HLA Alleles Contributes to Reduced HIV-1 Replication Capacity That May Be Largely Compensated for in Chronic Infection

Todd M. Allen, D. Heckerman, E. Rosenberg, 2010, Journal of Virology.

Tracking the culprit: HIV-1 evolution and immune selection revealed by single-genome amplification

B. Walker, Z. Brumme, 2009, The Journal of experimental medicine.

Expansion of pre-existing, lymph node-localized CD8+ T cells during supervised treatment interruptions in chronic HIV-1 infection.

M. Altfeld, B. Walker, J. van Lunzen, 2002, The Journal of clinical investigation.

Long-Term Antiretroviral Treatment Initiated at Primary HIV-1 Infection Affects the Size, Composition, and Decay Kinetics of the Reservoir of HIV-1-Infected CD4 T Cells

E. Rosenberg, F. Pereyra, B. Walker, 2014, Journal of Virology.

HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes

Charles E. DeZiel, D. Heckerman, F. Pereyra, 2014, Journal of Virology.

The Major Genetic Determinants of HIV-1 Control Affect HLA Class I Peptide Presentation

R. C. Rose, Todd M. Allen, David S. Rubin, 2010, Science.

Type 2 Bias of T cells expanded from the blood of melanoma patients switched to type 1 by IL-12p70 mRNA-transfected dendritic cells.

B. Walker, S. Adams, G. Alter, 2008, Cancer research.

Immune Selection for Altered Antigen Processing Leads to Cytotoxic T Lymphocyte Escape in Chronic HIV-1 Infection

M. Altfeld, B. Walker, E. Holmes, 2004, The Journal of experimental medicine.

Substantial Differences in Specificity of HIV-Specific Cytotoxic T Cells in Acute and Chronic HIV Infection

E. Rosenberg, M. Altfeld, B. Walker, 2001, The Journal of experimental medicine.

The rationale for immunotherapy in HIV-1 infection.

B. Walker, 1994, Journal of acquired immune deficiency syndromes.

Lactobacillus‐Deficient Cervicovaginal Bacterial Communities Are Associated with Increased HIV Acquisition in Young South African Women

Melis N. Anahtar, C. Huttenhower, B. Walker, 2017, Immunity.

Association of HLA-DRB1-restricted CD4+ T cell responses with HIV immune control

M. Carrington, B. Walker, Y. Qi, 2013, Nature Medicine.

Induction of HIV-1 replication in a chronically infected T-cell line by cytotoxic T lymphocytes.

B. Walker, T. Harrer, E. Harrer, 1993, Journal of acquired immune deficiency syndromes.

Coordinate linkage of HIV evolution reveals regions of immunological vulnerability

Todd M. Allen, V. Dahirel, K. Shekhar, 2011, Proceedings of the National Academy of Sciences.