D. Sackett

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Rules of evidence and clinical recommendations on the use of antithrombotic agents.

D. Cook, G. Guyatt, A. Laupacis, 1992, Chest.

Evidence-Based Medicine: How to Practice and Teach EBM

D. Sackett, 2018 .

Evidence based medicine: what it is and what it isn't

D. Sackett, R. Haynes, W. Richardson, 1996, BMJ.

Methodologic guidelines for systematic reviews of randomized control trials in health care from the Potsdam Consultation on Meta-Analysis.

D. Cook, D. Sackett, D. Cook, 1995, Journal of clinical epidemiology.

Evidence-based medicine. A new approach to teaching the practice of medicine.

A. Detsky, G. Guyatt, D. Cook, 1992, JAMA.

Beneficial effect of carotid endarterectomy in symptomatic patients with high-grade carotid stenosis.

D. Sackett, V. Hachinski, A. Fox, 1991, The New England journal of medicine.

Controversy in counting and attributing events in clinical trials.

D. Sackett, M. Gent, 1979, The New England journal of medicine.

Rational therapy in the neurosciences: the role of the randomized trial.

D. Sackett, 1986, Stroke.

Finding and applying evidence during clinical rounds: the "evidence cart".

D. Sackett, S. Straus, 1998, JAMA.

On the need for evidence-based medicine.

D. Sackett, W. Rosenberg, W. Rosenberg, 1995, Journal of public health medicine.

A proposal for structured reporting of randomized controlled trials. The Standards of Reporting Trials Group.

Curtis L. Meinert, David Moher, Kenneth F. Schulz, 1994, JAMA.

An assessment of clinically useful measures of the consequences of treatment.

D L Sackett, A Laupacis, A. Laupacis, 1988, The New England journal of medicine.

Compliance in Health Care

R. Brian Haynes, David L. Sackett, D. Sackett, 1979 .

The Ends of Human Life: Medical Ethics in a Liberal Polity

D. Sackett, Erich Groos, Erich Groos, 1992, Annals of Internal Medicine.

Evidence-based medicine.

D L Sackett, D. Sackett, 1997, Seminars in perinatology.

Evidence based medicine: what it is and what it isn't. 1996.

R Brian Haynes, David L Sackett, J A Muir Gray, 2007, Clinical orthopaedics and related research.

Evidence-based medicine: how to practice and teach EBM: 2nd ed

D. Sackett, 2000 .

Users' Guides to the Medical Literature: III. How to Use an Article About a Diagnostic Test: B. What Are the Results and Will They Help Me In Caring for My Patients?

G. Guyatt, D. Sackett, R. Jaeschke, 1994 .

Users' guides to the medical literature. III. How to use an article about a diagnostic test. B. What are the results and will they help me in caring for my patients? The Evidence-Based Medicine Working Group.

G. Guyatt, D. Sackett, R. Jaeschke, 1994, JAMA.

Transferring evidence from research into practice: 3. Developing evidence-based clinical policy

G. Guyatt, D. Cook, D. Sackett, 1997, Evidence Based Medicine.

The architecture of diagnostic research

D. Sackett, R. Haynes, 2002, BMJ : British Medical Journal.

Users ' Guides to the Medical Literature : III . How to Use an Article About a Diagnostic Test : A . Are the Results of the Study Valid ?

G. Guyatt, D. Sackett, R. Jaeschke, 2022 .

The measurement iterative loop: a framework for the critical appraisal of need, benefits and costs of health interventions.

D. Sackett, R. Haynes, P. Tugwell, 1985, Journal of chronic diseases.

Users' Guides to the Medical Literature: IX. A Method for Grading Health Care Recommendations

G. Guyatt, D. Cook, D. Sackett, 1995 .

Determining optimal therapy--randomized trials in individual patients.

G. Guyatt, D. Sackett, S. Pugsley, 1986, The New England journal of medicine.

Rules of evidence and clinical recommendations on the use of antithrombotic agents.

D. Sackett, David L. Sackett, 1989, Chest.

Benefit of carotid endarterectomy in patients with symptomatic moderate or severe stenosis. North American Symptomatic Carotid Endarterectomy Trial Collaborators.

D. Sackett, V. Hachinski, A. Fox, 1998, The New England journal of medicine.

Finding and Applying Evidence During Clinical Rounds

D. Sackett, S. Straus, 2011 .

How to Practice and Teach EBM

David L. Sackett, D. Sackett, P. Richardson, 2015 .

Why randomized controlled trials fail but needn't: 2. Failure to employ physiological statistics, or the only formula a clinician-trialist is ever likely to need (or understand!).

D L Sackett, D. Sackett, David L. Sackett, 2001, CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne.

On the need for evidence-based medicine.

D L Sackett, D. Sackett, W. Rosenberg, 1995, Therapie.

Users' guides to the medical literature. I. How to get started. The Evidence-Based Medicine Working Group.

G H Guyatt, A D Oxman, D L Sackett, 1993, JAMA.

Low-dose and high-dose acetylsalicylic acid for patients undergoing carotid endarterectomy: a randomised controlled trial

R Brian Haynes, David L Sackett, Vladimir Hachinski, 1999, The Lancet.

Users' guides to the medical literature. IX. A method for grading health care recommendations. Evidence-Based Medicine Working Group.

R J Cook, G H Guyatt, D L Sackett, 1995, JAMA.

The rational clinical examination. A primer on the precision and accuracy of the clinical examination.

D L Sackett, D. Sackett, 1992, JAMA.

Applying a Phase II Futility Study Design to Therapeutic Stroke Trials

Yuko Y Palesch, David L Sackett, Robert Woolson, 2005, Stroke.

Applying evidence to the individual patient.

D L Sackett, D. Sackett, S. Straus, 1999, Annals of oncology : official journal of the European Society for Medical Oncology.

Users' guides to the medical literature. II. How to use an article about therapy or prevention. A. Are the results of the study valid? Evidence-Based Medicine Working Group.

Gordon H. Guyatt, David L. Sackett, G. Guyatt, 1993, JAMA.

Users' Guides to the Medical Literature: II. How to Use an Article About Therapy or Prevention B. What Were the Results and Will They Help Me in Caring for My Patients?

Gordon H. Guyatt, Andrew D Oxman, Deborah J. Cook, 1994 .

Users' Guides to the Medical Literature: V. How to Use an Article About Prognosis

Gordon H. Guyatt, Andrew D Oxman, Deborah J. Cook, 1994 .

Users' Guides to the Medical Literature: III. How to Use an Article About a Diagnostic Test A. Are the Results of the Study Valid?

Gordon H. Guyatt, Andrew D Oxman, Deborah J. Cook, 1994 .

Users' guides to the medical literature. II. How to use an article about therapy or prevention. B. What were the results and will they help me in caring for my patients? Evidence-Based Medicine Working Group.

G H Guyatt, D L Sackett, G. Guyatt, 1994, JAMA.

Down with odds ratios!

Jonathan J. Deeks, David L. Sackett, D. Sackett, 1996, Evidence Based Medicine.

Users' Guides to the Medical Literature: XIX. Applying clinical trial results B. Guidelines for determining whether a drug is exerting (more than) a class effect.

D L Sackett, A Laupacis, A. Laupacis, 1999, JAMA.

Therapeutic priorities of Canadian internists.

A. Laupacis, D. Sackett, R. Roberts, 1990, CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne.

How should the results of clinical trials be presented to clinicians?

A. Laupacis, D. Sackett, C. Naylor, 1992, ACP Journal Club.

How the internet can help clinicians improve their clinical skills.

D. Sackett, 2000, MedGenMed : Medscape general medicine.

On some clinically useful measures of the accuracy of diagnostic tests

D. Sackett, S. Straus, 1998, Evidence Based Medicine.

What is the Evidence for Mentorship

D. Sackett, S. Straus, 2013 .

Clinical Validity of a Negative Venogram in Patients with Clinically Suspected Venous Thrombosis

D. Sackett, J. Hirsh, D. Taylor, 1981, Circulation.

The Need for Evidence-Based Medicine

D L Sackett, D. Sackett, W. Rosenberg, 1995, Health economics.

Why we need large, simple studies of the clinical examination: the problem and a proposed solution

D. Sackett, S. Straus, F. McAlister, 1999, The Lancet.

Replacement of venography in suspected venous thrombosis by impedance plethysmography and 125I-fibrinogen leg scanning: a less invasive approach.

D. Sackett, J. Hirsh, D. Taylor, 1981, Annals of internal medicine.

Hypertension in a family practice.

D. Sackett, K. Rudnick, S. Hirst, 1977, Canadian Medical Association journal.

Patients and therapies: getting the two together.

D. Sackett, 1978 .

How to detect and manage low patient compliance in chronic illness.

D. Sackett, R. Haynes, D. Taylor, 1980, Geriatrics.

A practical guide to informed consent to treatment

D. Sackett, A. Oxman, I. Chalmers, 2001, BMJ : British Medical Journal.

Commentaries on “First-Rank Symptoms or Rank-and-File Symptoms?”

T. Crow, D. Sackett, P. McGuffin, 1996, British Journal of Psychiatry.

Further conclusions from the extracranial-intracranial bypass trial.

Bruce D. Haynes, D. Sackett, V. Hachinski, 1986, Surgical neurology.

Outcome of patients discharged from a coronary care unit with a diagnosis of "chest pain not yet diagnosed".

R. Hunt, D. Sackett, E. Fallen, 1996, CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne.

Are the results of the extracranial-intracranial bypass trial generalizable?

D. Sackett, V. Hachinski, A. Fox, 1987, The New England journal of medicine.

Evaluation of the Hypertensive Patient with Emphasis on Detecting Curable Causes

D. Sackett, A. Chobanian, P. Levy, 1969 .

Manipulation of the therapeutic regimen to improve compliance: conceptions and misconceptions.

D. Sackett, R. Haynes, D. Taylor, 1977, Clinical pharmacology and therapeutics.

Hypertension control, compliance and science.

D. Sackett, R. Haynes, D. Taylor, 1977, American Heart Journal.

The Problem of Compliance with Antihypertensive Regimens

D. Sackett, R. Haynes, D. Taylor, 1983, Drugs.

Clinician trialist rounds: 28. When RCT participants are lost to follow-up. Part 1: Why even a few can matter

D. Sackett, P. Devereaux, M. Walsh, 2015, Clinical trials.

Turning a blind eye:Why we don't test for blindness at the end of our trials

D. Sackett, 2004, BMJ : British Medical Journal.

Quality-of-care appraisal in primary care: a quantitative method.

D. Sackett, W. Spitzer, J. Bell, 1975, Annals of internal medicine.

How Can You Evaluate the Impact of a Mentorship Program

D. Sackett, S. Straus, 2013 .

How Can You Initiate and Maintain a Mentorship Progam

D. Sackett, S. Straus, 2013 .

Clinical assessment of the reliability of the examination (CARE)

D. Sackett, S. Straus, F. McAlister, 2000, ACP journal club.

Evidence-based medicine

D. Sackett, G. Norman, P. Aveyard, 1995, The Lancet.

Hypertension V. Compliance with antihypertensive therapy.

D. Sackett, 1980, Canadian journal of public health = Revue canadienne de sante publique.

Using research findings in clinical practice

D L Sackett, D. Sackett, S. Straus, 1998, BMJ.

Effects of labelling on income, work and social function among hypertensive employees.

D. Sackett, R. Haynes, A. Gafni, 1984, Journal of chronic diseases.

The rational clinical examination. Does this patient have splenomegaly?

D. Sackett, A. Barkun, S. Grover, 1993, JAMA.

Does This Patient Have Splenomegaly

D. Sackett, A. Barkun, S. Grover, 1993 .

Screening for asymptomatic carotid stenosis should not be performed. Uses and abuses of diagnostic tests in asymptomatic people

D. Sackett, 2008 .

Longterm follow-up of absenteeism among working men following the detection and treatment of their hypertension.

D. Sackett, R. Haynes, E. Gibson, 1981, Clinical and investigative medicine. Medecine clinique et experimentale.

Clinical diagnosis and the clinical laboratory.

D. Sackett, 1978, Clinical and investigative medicine. Medecine clinique et experimentale.

19 2 The architecture of diagnostic research

D. Sackett, R. Haynes, 2001 .

2 The architecture of diagnostic research

D. Sackett, R. Haynes, 2001 .

Laboratory screening: a critique.

D. Sackett, 1975, Federation proceedings.

Prevention of functional impairment by endarterectomy for symptomatic high-grade carotid stenosis. North American Symptomatic Carotid Endarterectomy Trial Collaborators.

D. Sackett, R. Haynes, H. Barnett, 1994, JAMA.

The Family Physician And the Periodic Heath

D. Sackett, 2008 .

The Usefulness of LaboratoryTests in 366 CLINICAL CHEMISTRY

D. Sackett, 2004 .

Periodic health examinations and multiphasic screening.

D. Sackett, J. Mcclaran, C. Bombardier, 1973, Canadian Medical Association journal.

CONTROVERSY IN THE DETECTION OF DISEASE

D. Sackett, W. Holland, 1975, The Lancet.

Screening for early detection of disease: to what purpose?

D. Sackett, 1975, Bulletin of the New York Academy of Medicine.

One year mortality outcomes of all coronary and intensive care unit patients with acute myocardial infarction, unstable angina or other chest pain in Hamilton, Ontario, a city of 375,000 people.

D. Sackett, J. Singer, J. Cairns, 1989, The Canadian journal of cardiology.

Patient compliance with antihypertensive regimens.

D. Sackett, R. Haynes, D. Taylor, 1978, Patient counselling and health education.

The Burlington randomized trial of the nurse practitioner: health outcomes of patients.

D. Sackett, W. Spitzer, M. Gent, 1974, Annals of internal medicine.

Zlinkoff honor lecture

D. Sackett, D. Sackett, 1987, Journal of general internal medicine.

The rational clinical examination. A primer on the precision and accuracy of the clinical examination.

D. Sackett, 1992, JAMA.

Transferring evidence from research into practice: 4. Overcoming barriers to application

G. Guyatt, D. Cook, D. Sackett, 1997, Evidence Based Medicine.

Transferring evidence from research into practice: 2. Getting the evidence straight

G. Guyatt, D. Sackett, R. Haynes, 1997, Evidence-Based Medicine.

Summarising the effects of therapy: a new table and some more terms

D. Sackett, R. Haynes, 1997, Evidence Based Medicine.

Clinician-trialist rounds: 14. Ways to advance your career by saying ‘no’ – part 2: When to say ‘no’, and why

D. Sackett, A. Oxman, 2013, Clinical trials.

Process Versus Outcome in Hypertension: A Positive Result

D. Sackett, R. Haynes, D. Taylor, 1982, Circulation.

The Cochrane Collaboration.

D. Sackett, 1994, ACP journal club.

…so little time, and …

D. Sackett, 1997, Evidence Based Medicine.

Evidence-based medicine and treatment choices

D. Sackett, 1997, The Lancet.

Thrombolytic Agents: The Science of the Art of Choosing the Better Treatment

D. Sackett, M. Farkouh, J. Lang, 1994, Annals of Internal Medicine.

70 Choosing an appropriate dichotomous effect measure for meta-analysis: Empirical evidence of the appropriateness of the odds ratio and relative risk

D. Sackett, D. Altman, J. Deeks, 1997 .

Why we need large, simple studies of the clinical examination: the problem and a proposed solution. CARE-COAD1 group. Clinical Assessment of the Reliability of the Examination-Chronic Obstructive Airways Disease Group.

D. Sackett, S. Straus, F. McAlister, 1999, Lancet.

Clinician-trialist rounds: 17. Mind your explanatory and pragmatic attitudes! Part 2: How?

D. Sackett, 2013, Clinical trials.

How to Use Overviews of Prevention Trials to Treat Individual Patients

D. Sackett, W. Rosenberg, J. Mant, 1996 .

COMMENTARY A Science for the Art of Consensus

D. Sackett, 1997 .

Methodologic Guides for the Evaluation of Community Developmental Screening Programs

L. Chambers, D. Sackett, W. Feldman, 1985 .

Sample Size for Randomized Trials in Stroke Prevention. How Many Patients Do We Need?

D. Sackett, R. Haynes, D. Taylor, 1984, Stroke.

Clinician-trialist rounds: 6. Testing for blindness at the end of your trial is a mug's game

D. Sackett, 2011, Clinical trials.

Dealing with the media.

G. Guyatt, D. Sackett, P. Tugwell, 2006, Journal of clinical epidemiology.

A randomized trial of aspirin and sulfinpyrazone in patients with threatened stroke. Results and methodologic issues.

D. Sackett, H. Barnett, D. Taylor, 1980, Circulation.

Importance of and satisfaction with work and professional interpersonal issues: a survey of physicians practicing general internal medicine in Ontario.

D. Cook, D. Sackett, L. Griffith, 1995, CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne.

Clinician-trialist rounds: 26. Sabbaticals. Part 1: Should I take a sabbatical?

D. Sackett, S. Straus, 2015, Clinical trials.

The Qualification and Disqualification of Patients and Events in Long-Term Cardiovascular Clinical Trials

D. Sackett, M. Gent, 1979, Thrombosis and Haemostasis.

Teaching critical appraisal: no quick fixes.

D. Sackett, J. Parkes, 1998, CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne.

How to keep up with the medical literature: VI. How to store and retrieve articles worth keeping.

D Fitzgerald, G H Guyatt, C J Walker, 1986, Annals of internal medicine.

Determining causation--a case study: adrenocorticosteroids and osteoporosis. Should the fear of inducing clinically important osteoporosis influence the decision to prescribe adrenocorticosteroids?

G H Guyatt, D L Sackett, C E Webber, 1984, Journal of chronic diseases.

Combined use of leg scanning and impedance plethysmography in suspected venous thrombosis. An alternative to venography.

D. Sackett, J. Hirsh, P. Powers, 1977, The New England journal of medicine.

The value of adding impedance plethysmography to 125I-fibrinogen leg scanning for the detection of deep vein thrombosis in high risk surgical patients: a comparative study between patients undergoing general surgery and hip surgery.

D. Sackett, J. Hirsh, P. Powers, 1979, Thrombosis research.

Hypertension: The Family Physician's Role.

D. Sackett, K. Rudnick, S. Hirst, 1978, Canadian family physician Medecin de famille canadien.

Why Won't Hypertensive Patients Take Their Medicine?

D. Sackett, 1977, Canadian family physician Medecin de famille canadien.

The periodic health examination : 2. 1984 update

D. Sackett, R. Battista, I. McWhinney, 1984 .

How to keep up with the medical literature: V. Access by personal computer to the medical literature.

D Fitzgerald, G H Guyatt, C J Walker, 1986, Annals of internal medicine.

Fenoterol and fatal asthma

D. Sackett, H. Shannon, G. Browman, 1990, The Lancet.

The usefulness of laboratory tests in health-screening programs.

D. Sackett, 1973, Clinical chemistry.

The hypertensive patient: 5. Compliance with therapy.

D. Sackett, 1979, Canadian Medical Association journal.

OBSOLETE: Clinical Epidemiology

D. Sackett, 2017 .

Teaching critical appraisal

D. Sackett, 1990, Journal of general internal medicine.

Cardiovascular diseases.

D. Sackett, 1974, Lancet.

Aspirin - Effective in Males Threatened with Stroke

D. Sackett, H. Barnett, J. McDonald, 1978, Stroke.

13 steps, 100 people, and 1 000 000 thanks

D. Sackett, R. Haynes, 1997, Evidence Based Medicine.

Negative x-ray and CT studies in CNS disease.

D. Sackett, J. Meharchand, 1983, Hospital practice.

Some Effective Mentoring Strategies and Tactics: Part 4: Mentoring for Knowledge Dissemination*

D. Sackett, S. Straus, 2013 .

The Potential Role Of Single-Patient Randomized Controlled Trials (N-Of-1 RCTs) In Clinical Practice

D. Cook, D. Sackett, R. Jaeschke, 1992, The Journal of the American Board of Family Medicine.

Diagnosis and treatment of chronic arterial insufficiency of the lower extremities: a critical review.

D L Sackett, D. Sackett, D. Strandness, 1996, Circulation.

A 1955 clinical trial report that changed my career

D. Sackett, 2010, Journal of the Royal Society of Medicine.

Equipoise, a term whose time (if it ever came) has surely gone.

D. Sackett, David L. Sackett, 2000, CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne.

The hypertensive patient: 4. Stepped-care therapy.

D. Sackett, 1979, Canadian Medical Association journal.

Simplification of the sequential impedance plethysmograph technique without loss of accuracy.

D. Sackett, J. Hirsh, D. Taylor, 1980, Thrombosis research.

Randomized trial of therapy with platelet antiaggregants for threatened stroke. 2: Observations on the pathogenesis and natural history of threatened stroke.

D. Sackett, H. Barnett, D. Taylor, 1980, Canadian Medical Association journal.

Guidelines for improving meta-analysis

D. Sackett, W. Spitzer, 1994, The Lancet.

Continuous intravenous heparin compared with intermittent subcutaneous heparin in the initial treatment of proximal-vein thrombosis.

G. Raskob, D. Sackett, J. Hirsh, 1986, The New England journal of medicine.

Establishing therapeutic equivalency. What is a clinically significant difference?

A. Detsky, D. Sackett, 1986, Archives of internal medicine.

Rules of evidence and clinical recommendations on the use of antithrombotic agents.

D. Sackett, 1989, Chest.

Nutritional management of hypertension: controversies and frontiers.

D. Sackett, 1986, Canadian journal of physiology and pharmacology.

The diagnostic value of the fibrinogen/fibrin fragment E antigen assay in clinically suspected deep vein thrombosis.

D. Sackett, J. Hirsh, M. Gent, 1982, Blood.

Participants in research

D. Sackett, 2005, BMJ : British Medical Journal.

What is a health care trial?

D. Sackett, A. Feinstein, W. Spitzer, 1975, JAMA.

Compliance trials and the clinician.

D. Sackett, 1978, Archives of internal medicine.

Observer variation in the interpretation of lower limb venograms.

D. Sackett, D. Taylor, M. Mclachlan, 1979, AJR. American journal of roentgenology.

Coronary care unit utilization in Hamilton, Ontario, a city of 375,000 people.

D. Sackett, J. Singer, J. Cairns, 1988, The Canadian journal of cardiology.

Labeling of hypertensive patients.

D. Sackett, R. Haynes, D. W. Taylor, 1983, The New England journal of medicine.

Rules of evidence and clinical recommendations on the use of antithrombotic agents.

G. Guyatt, D. Cook, G. Guyatt, 1992, Chest.

Ratios of pleural fluid to serum immunoglobulins in malignant pleural effusions

D. Sackett, D. Sackett, S. D. Desai, 1983, Cancer.

High marks for the physical exam.

D. Sackett, S. Straus, F. McAlister, 2000, CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne.

The science of the art of the clinical examination.

D. Rennie, D. Sackett, 1992, JAMA.

Splenomegaly and Percussion: Is the Background Noise Due to Tongue in Cheek?-Reply

D. Sackett, A. Barkun, S. Grover, 1994 .

Meta-analytic methods for diagnostic test accuracy. Discussion

D. Sackett, 1995 .

A Surrealistic Mega-Analysis of Redisorganization Theories

D. Sackett, A. Oxman, I. Chalmers, 2005, Journal of the Royal Society of Medicine.

Mentorship in Academic Medicine: Straus/Mentorship in Academic Medicine

D. Sackett, S. Straus, 2013 .

POSSIBLE IMMUNOLOGICAL INFLUENCE ON SEX RATIO

D. Sackett, K. Dronamraju, 1967 .

A Classic Manuscript Reprinted in Celebration of 25 Years of Progress

D. Sackett, W. Spitzer, R. Roberts, 1990 .

Clinician-trialist rounds: 21. The presenting complaints, diagnoses and treatments of mentorships in trouble. Part 1: Dysfunctional mentorship meetings

D. Sackett, 2014, Clinical trials.

Educational package on hypertension for primary care physicians.

D. Sackett, R. Haynes, D. Taylor, 1984, Canadian Medical Association journal.

Evidence based medicine: What it is and what it isn't (reprinted from BMJ, vol 312, pg 71-72, 1996)

David L. Sackett, Wmc Rosenberg, Jam Gray, 2007 .

Rules of evidence and clinical recommendations for the management of patients.

D. Sackett, 1993, The Canadian journal of cardiology.

Evaluation of neonatal-intensive-care program.

D L Sackett, G W Torrance, M H Boyle, 1981, The New England journal of medicine.

Active-control equivalence trials and antihypertensive agents.

D. Sackett, F. McAlister, F. A. McAlister, 2001, The American journal of medicine.

Randomized clinical trials of antihypertensive drugs: all that glitters is not gold.

D. Sackett, S. Straus, F. A. McAlister, 1998, CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne.

Applying overviews and meta-analyses at the bedside.

D. Sackett, 1995, Journal of clinical epidemiology.

Dialyzer re-use--a multiple crossover study with random allocation to order of treatment.

D. Sackett, D. Churchill, D. Taylor, 1988, Nephron.

How to keep up with the medical literature: III. Expanding the number of journals you read regularly.

D Fitzgerald, G H Guyatt, C J Walker, 1986, Annals of internal medicine.

How to keep up with the medical literature: II. Deciding which journals to read regularly.

D Fitzgerald, G H Guyatt, C J Walker, 1986, Annals of internal medicine.

How to keep up with the medical literature: I. Why try to keep up and how to get started.

D Fitzgerald, G H Guyatt, C J Walker, 1986, Annals of internal medicine.

Analysis and reporting of factorial trials: a systematic review.

Douglas G Altman, Sharon E Straus, David L Sackett, 2003, JAMA.

Patient Compliance: A Multifaceted Problem With No Easy Solution

D. Sackett, R. Haynes, 1981 .

How to read clinical journals.

D L Sackett, D. Sackett, 1982, Canadian Medical Association journal.

Grades of recommendation for antithrombotic agents.

G. Guyatt, D. Cook, D. Sackett, 1998, Chest.

Multiplication of Vaccinia Virus in Serum-free and Serum-containing Cell Cultures

D. Sackett, L. Alfred, ROBERT W. PUMPER, 1960, Nature.

Design, Measurement and Analysis in Clinical Trials

D. Sackett, 1975 .

IMPROVEMENT OF MEDICATION COMPLIANCE IN UNCONTROLLED HYPERTENSION

D. Sackett, R. Haynes, R. Roberts, 1976, The Lancet.

Why Clinical Research

D. Sackett, B. Walters, 1991 .

When was a "negative" clinical trial big enough? How many patients you needed depends on what you found.

A. Detsky, D. Sackett, 1985, Archives of internal medicine.

Assessing the effectiveness of community screening programs.

L. Chambers, D. Sackett, D Cadman, 1984, JAMA.

Clinician-trialist rounds: 13. Ways to advance your career by saying ‘no’ – part 1: why to say ‘no’ (nicely), and saying ‘no’ to email

D. Sackett, A. Oxman, 2012, Clinical trials.

HARLOT plc: an amalgamation of the world's two oldest professions

Andrew D Oxman, David L Sackett, D. Sackett, 2003, BMJ : British Medical Journal.

What proportion of primary psychiatric interventions are based on evidence from randomised controlled trials?

D. Sackett, J. Geddes, D. Game, 1996, Quality in health care : QHC.

Criteria for evaluating evidence that laboratory abnormalities are associated with the development of venous thromboembolism.

D. Sackett, S. Straus, Jeffrey S. Ginsberg, 2000, CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne.

Functional status changes following medical or surgical treatment for cerebral ischemia. Results of the extracranial-intracranial bypass study.

D. Sackett, R. Haynes, H. Barnett, 1987, JAMA.

Effect of awareness of a randomized controlled trial on use of experimental therapy.

D. Sackett, A. Garg, W. Clark, 2003, JAMA.

Warfarin sodium versus low-dose heparin in the long-term treatment of venous thrombosis.

M Gent, E Genton, D. Sackett, 1979, The New England journal of medicine.

A randomized clinical trial of the Leboyer approach to childbirth.

D. Sackett, M. Enkin, S. Saigal, 1980, The New England journal of medicine.

Methods of Blinding in Reports of Randomized Controlled Trials Assessing Pharmacologic Treatments: A Systematic Review

D. Sackett, I. Boutron, A. Hrõbjartsson, 2006, PLoS medicine.

How to Use an Article About Therapy or Prevention

Gordon H. Guyatt, Deborah J. Cook, David L. Sackett, 1995 .

Clinical epidemiology. what, who, and whither.

D. Sackett, 2002, Journal of clinical epidemiology.

USERS' GUIDES TO THE MEDICAL LITERATURE. II: HOW TO USE AN ARTICLE ABOUT THERAPY OR PREVENTION A. ARE THE RESULTS OF THE STUDY VALID ?

G H Guyatt, D L Sackett, G. Guyatt, 1993 .

Commentary: Measuring the success of blinding in RCTs: don't, must, can't or needn't?

David L Sackett, D. Sackett, 2007, International journal of epidemiology.

The fall of "clinical research" and the rise of "clinical-practice research".

D. Sackett, 2000, Clinical and investigative medicine. Medecine clinique et experimentale.

Clinician-trialist rounds: 25. Designing an evidence-based introductory graduate course in clinical trials. Part 2: Applying the evidence to your RCT course design

D. Sackett, G. Norman, 2015, Clinical trials.

Clinician-trialist rounds: 7. Mentoring: why every clinician-trialist needs to get mentored

D. Sackett, S. Straus, 2011, Clinical trials.

Clinical recommendations using levels of evidence for antithrombotic agents.

D L Sackett, A Laupacis, G. Guyatt, 1995, Chest.

Users' Guides to the Medical Literature: IV. How to Use an Article About Harm

Gordon H. Guyatt, Andrew D Oxman, Deborah J. Cook, 1994 .

Inpatient general medicine is evidence based

D. Sackett, D. L Sackett, J Ellis, 1995, The Lancet.

Non-use and misuse of measles vaccine.

D. Sackett, W. Feldman, T. Nwe, 1973, Canadian family physician Medecin de famille canadien.

Failure of weight reduction to reduce mildly elevated blood pressure: a randomized trial.

D. Sackett, R. Haynes, A. Logan, 1984, Journal of hypertension.

Can We Learn Anything from Small Trials?

D L Sackett, D. Sackett, D J Cook, 1993, Annals of the New York Academy of Sciences.

Research Methods for Obtaining Primary Evidence

D. Sackett, R. Jaeschke, Roman Jaeschke, 1989, International Journal of Technology Assessment in Health Care.

The arrogance of preventive medicine.

David L Sackett, D. Sackett, 2002, CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne.

RANDOMISED CLINICAL TRIAL OF STRATEGIES FOR IMPROVING MEDICATION COMPLIANCE IN PRIMARY HYPERTENSION

D. Sackett, R. Haynes, D. Taylor, 1975, The Lancet.

Applying the results of trials and systematic reviews to Individual patients

Gordon H. Guyatt, Paul Glasziou, David L. Sackett, 1998, Evidence Based Medicine.

Superiority trials, non-inferiority trials, and prisoners of the 2-sided null hypothesis

D. Sackett, D. Sackett, 2004, ACP journal club.

Labelling in hypertension: a review of the behavioural and psychological consequences.

D. Sackett, R. Haynes, D. Taylor, 1984, Journal of chronic diseases.

Increased absenteeism from work after detection and labeling of hypertensive patients.

R B Haynes, D L Sackett, D. Sackett, 1978, The New England journal of medicine.

How to keep up with the medical literature: IV. Using the literature to solve clinical problems.

D Fitzgerald, G H Guyatt, C J Walker, 1986, Annals of internal medicine.

Can Simple Clinical Measurements Detect Patient Noncompliance?

D. Sackett, R. Haynes, B. Haynes, 1980, Hypertension.

Users' Guides to the Medical Literature: I. How to Get Started

Gordon H. Guyatt, Andrew D. Oxman, Andrew D Oxman, 1993 .

Need for expertise based randomised controlled trials

Gordon H Guyatt, S D Walter, Holger J Schünemann, 2005, BMJ : British Medical Journal.

A clinician's guide for conducting randomized trials in individual patients.

G. Guyatt, D. Sackett, R. Roberts, 1988, CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne.

The Burlington randomized trial of the nurse practitioner.

D. Sackett, W. Spitzer, M. Gent, 1974, The New England journal of medicine.

Persistence of reduction in blood pressure and mortality of participants in the Hypertension Detection and Follow-up Program. Hypertension Detection and Follow-up Program Cooperative Group.

D. Sackett, M. Blaufox, B. Davis, 1988, JAMA.

Haynes architecture of diagnostic research Evidence base of clinical diagnosis : The

D. Sackett, 2002 .

Why did I become a clinician-trialist?

D. Sackett, 2015, Journal of the Royal Society of Medicine.

How are we to determine whether dietary interventions do more good than harm to hypertensive patients?

D. Sackett, 1986, Canadian journal of physiology and pharmacology.

Why randomized controlled trials fail but needn't: 1. Failure to gain "coal-face" commitment and to use the uncertainty principle.

D. Sackett, David Sackett, 2000, CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne.

Lung cancer and air pollution in an industrial city--a geographical analysis.

D. Sackett, C. Hertzman, H. Shannon, 1988, Canadian journal of public health = Revue canadienne de sante publique.

Inpatient general medicine is evidence based. A-Team, Nuffield Department of Clinical Medicine.

D. Sackett, J. Ellis, J. Rowe, 1995, Lancet.

Cost effectiveness of clinical diagnosis, venography, and noninvasive testing in patients with symptomatic deep-vein thrombosis.

D L Sackett, D. Sackett, G. Stoddart, 1981, The New England journal of medicine.

The rational clinical examination. Does this patient have a clinically important carotid bruit?

A. Laupacis, D. Sackett, Truls Østbye, 1993, JAMA.

Clinician-trialist rounds: 24. Modernizing your introductory graduate course in clinical trials. Part 1: Commonsense meets evidence

D. Sackett, G. Norman, 2014, Clinical trials.

Problems in the handling of clinical and research evidence by medical practitioners.

R B Haynes, D L Sackett, P Tugwell, 1983, Archives of internal medicine.

A randomized trial of continuing medical education.

D L Sackett, D. Sackett, V Neufeld, 1982, The New England journal of medicine.

A controlled trial of teaching critical appraisal of the clinical literature to medical students.

D. Sackett, R. Haynes, P. Tugwell, 1987, JAMA.

The competing objectives of randomized trials.

D. Sackett, 1980, The New England journal of medicine.

Evidence base of clinical diagnosis: The architecture of diagnostic research

R B Haynes, D L Sackett, D. Sackett, 2002 .

Electrocardiographic Precordial Mapping in Anterior Myocardial Infarction

D. Sackett, J. Hirsh, D. Taylor, 1978, Circulation.

A cost-effectiveness analysis of alternative approaches for long-term treatment of proximal venous thrombosis.

G. Raskob, D. Sackett, J. Hirsh, 1984, JAMA.

Cost-effectiveness of primary and secondary prevention of fatal pulmonary embolism in high-risk surgical patients.

D. Sackett, G. Stoddart, J. Hirsh, 1982, Canadian Medical Association journal.

Clinician-trialist rounds: 5. Cointervention bias – how to diagnose it in their trial and prevent it in yours

D. Sackett, 2011, Clinical trials.

The accuracy of patient history, wheezing, and laryngeal measurements in diagnosing obstructive airway disease. CARE-COAD1 Group. Clinical Assessment of the Reliability of the Examination-Chronic Obstructive Airways Disease.

D. Sackett, S. Straus, F. McAlister, 2000, JAMA.

1 Evidence-based obstetrics and gynaecology

D. Sackett, I. Cooke, 1996 .

Clinical Epidemiology: How to Do Clinical Practice Research

Gordon H. Guyatt, Peter Tugwell, R. Brian Haynes, 1991 .

COMPLIANCE WITH ANTIHYPERTENSIVE DRUG THERAPY *

D. Sackett, R. Haynes, D. Taylor, 1978, Annals of the New York Academy of Sciences.

An empirical demonstration of Berkson's bias.

D. Sackett, W. Spitzer, R. Roberts, 1978, Journal of chronic diseases.

Pulmonary embolism in outpatients with pleuritic chest pain.

G. Raskob, D. Sackett, J. Hirsh, 1988, Archives of internal medicine.

Neuroimaging study of placebo analgesia in humans

D. Sackett, Y. Qiu, Hao Xu, 2009, Neuroscience Bulletin.

Explanatory and pragmatic clinical trials: a primer and application to a recent asthma trial.

D. Sackett, 2011, Polskie Archiwum Medycyny Wewnetrznej.

Possible risk factors in the development of venous thrombosis. Gastrointestinal disease, infection and dehydration.

D. Sackett, 1972, The Milbank Memorial Fund quarterly.

Transferring evidence from research into practice: 1. The role of clinical care research evidence in clinical decisions

G H Guyatt, R B Haynes, D L Sackett, 1996, Evidence Based Medicine.

The trials of Dr. Bernard Fisher: a European perspective on an American episode.

D. Sackett, O. Dalesio, R. Doll, 1997, Controlled clinical trials.

Accuracy of history, wheezing, and forced expiratory time in the diagnosis of chronic obstructive pulmonary disease

D. Sackett, S. Straus, F. McAlister, 2002, Journal of General Internal Medicine.

Evidence-based medicine

D. Sackett, B. Haynes, T. Marshall, 1995, The Lancet.

Clinician-trialist rounds: 10. Mentoring – part 4: attributes of an effective mentor

D. Sackett, S. Straus, 2012, Clinical trials.

Clinician-trialist rounds: 9. Mentoring – part 3: the structure and function of effective mentoring: advice and protection

D. Sackett, S. Straus, 2012, Clinical trials.

Clinician-trialist rounds: 8. Mentoring – part 2: the structure and function of effective mentoring linkage, resources, and academic opportunities

Sharon E Straus, David L Sackett, D. Sackett, 2012, Clinical trials.

Campaign to revitalise academic medicine: Don't believe us

D. Sackett, 2004, British medical journal.

The sins of expertness and a proposal for redemption

David L Sackett, D. Sackett, 2000, BMJ : British Medical Journal.

Clinician-trialist rounds: 16. Mind your explanatory and pragmatic attitudes! – part 1: what?

D. Sackett, 2013, Clinical trials.

Clinician-trialist rounds: 3. Priority setting for academic success

D. Sackett, 2011, Clinical trials.

On the determinants of academic success as a clinician-scientist.

D. Sackett, David L. Sackett, 2001, Clinical and investigative medicine. Medecine clinique et experimentale.

Guidelines and killer Bs

D. Sackett, A. Oxman, 1999, Evidence Based Medicine.

Evidence-based medicine.

D. Sackett, D Sackett, 1998, Lancet.

Bringing evidence to the clinic.

D. Sackett, S. Straus, 1998, Archives of dermatology.

Why randomized controlled trials fail but needn't: a new series is launched.

D L Sackett, D. Sackett, J. Hoey, 2000, CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne.

Heroin vs morphine for cancer pain?

D. Sackett, H. Bush, M. Levine, 1986, Archives of internal medicine.

Practical management of low compliance with antihypertensive therapy: a guide for the busy practitioner.

D. Sackett, R. Haynes, D. Taylor, 1978, Clinical and investigative medicine. Medecine clinique et experimentale.

Self-recording of blood pressure in the management of hypertension.

D. Sackett, C. Dunnett, D. W. Taylor, 1978, Canadian Medical Association journal.

Does a mailed continuing education program improve physician performance? Results of a randomized trial in antihypertensive care.

R B Haynes, D L Sackett, D. Sackett, 1986, JAMA.

Cancer risk in ulcerative colitis: scientific requirements for the study of prognosis.

D. Sackett, G. Whelan, 1980, Gastroenterology.

Clinician-trialist rounds: 19. Faux pas or fraud? Identifying centers that have fabricated their data in your multi-center trial

D. Sackett, J. Pogue, 2014, Clinical trials.

Time to put the Canadian Institutes of Health Research on trial.

D. Sackett, 1999, CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne.

Evidence-based Medicine: A Framework for Emotional Regulation, Intuition, and Conscious Engagement

D. Sackett, 2014 .

Controversy in neurology: the Canadian study on TIA and aspirin. A critique of the Canadian TIA study. Reply.

D. Sackett, H. Barnett, D. Taylor, 1979, Annals of Neurology.

The relationship between basic biomedical research and the design and analysis of clinical trials.

D. Sackett, D. Taylor, M. Gent, 1983, Thrombosis research. Supplement.

1. Design and main results of the trial.

H J Barnett, M Gent, D L Sackett, 1980, Canadian Medical Association journal.

THE MEDICAL UNDERGRADUATE PROGRAMME AT McMASTER UNIVERSITY: LEARNING EPIDEMIOLOGY AND BIOSTATISTICS IN AN INTEGRATED CURRICULUM

D. Sackett, S. Leeder, Stephen R. Leeder, 1976, The Medical journal of Australia.

How Can You Scale Up and Sustain a Mentorship Program

D. Sackett, S. Straus, 2013 .

Evidence-based medicine.

D. Sackett, 2005, Spine.

The periodic health examination.

D. Sackett, 1980, Canadian Medical Association journal.

A Randomized Trial of Aspirin and Sulfinpyrazone

D. Sackett, H. Barnett, D. Taylor, 2005 .

What drove the Evidence Cart? Bringing the library to the bedside

D. Sackett, S. Straus, A. Eisinga, 2016, Journal of the Royal Society of Medicine.

Screening in family practice: prevention, levels of evidence, and the pitfalls of common sense.

D. Sackett, 1987, Journal of Family Practice.

Derivation of the SLEDAI. A disease activity index for lupus patients. The Committee on Prognosis Studies in SLE.

D. Sackett, C. Bombardier, D. Gladman, 1992, Arthritis and rheumatism.

EBM: Savior or Scourge of Clinical Practice

D. Sackett, 2008, The American Journal of Gastroenterology.

Aspirin, sulfinpyrazone, or both in unstable angina. Results of a Canadian multicenter trial.

D. Sackett, J. Singer, J. Cairns, 1985, The New England journal of medicine.

Users' guides to the medical literature. IV. How to use an article about harm. Evidence-Based Medicine Working Group.

D. Sackett, M. Wilson, R. Hayward, 1994, JAMA.

How Can You Initiate Mentorship

D. Sackett, S. Straus, 2013 .

Clinical prediction guides

D. Sackett, T. McGinn, D Sackett, 1998, Evidence Based Medicine.

Hypertension control in two Canadian communities: evidence for better treatment and overlabelling.

D. Sackett, R. Haynes, D. Taylor, 1986, Journal of hypertension.

On the clinically important difference

Carol M. Ashton, Nelda P. Wray, David L. Sackett, 1992, ACP Journal Club.

What are the Characteristics and Behaviors of Effective Mentors and Mentees

D. Sackett, S. Straus, 2013 .

Reducing patient morbidity from high-efficiency hemodialysis: a double-blind crossover trial.

D. Sackett, D. Taylor, A. Shimizu, 1983, Transactions - American Society for Artificial Internal Organs.

Six pairs of things to celebrate on International Clinical Trials Day

D. Sackett, 2013, Trials.

The Potential Role Of Single-Patient Randomized Controlled Trials (N-Of-1 RCTs) In Clinical Practice

D. Sackett, R. Jaeschke, D. Cook, 1992, The Journal of the American Board of Family Medicine.

Users' Guides to the Medical Literature: V. How to Use an Article About Prognosis

G. Guyatt, D. Cook, A. Laupacis, 1994 .

The impact of continuing education on the quality of patient care.

D. Sackett, V. Neuféld, K. Rudnick, 1983, Canadian family physician Medecin de famille canadien.

Users ' Guides to the Medical Literature : IV . How to Use an Article About Harm

D. Sackett, M. Wilson, R. Hayward, 2010 .

Clinical Epidemiology: How to Do Clinical Practice Research

G. Guyatt, D. Sackett, R. Haynes, 1991 .

Prevalence survey of cytomegalovirus infection in children in Chengdu.

D. Sackett, T. Wu, Y. Huang, 1990, American journal of epidemiology.

The rational clinical examination. Does this patient have a clinically important carotid bruit?

A. Laupacis, D. Sackett, Truls Østbye, 1993, JAMA.