G. Flynn

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Substituent Constants for Correlation Analysis in Chemistry and Biology.

G. Flynn, 1980 .

Drug delivery from tropical formulations : theoretical prediction and experimental assessment

N. Weiner, G. Flynn, R. Curl, 1990 .

Drug absorption kinetics in goldfish.

G. Flynn, O. S. Carpenter, S. H. Yolkowsky, 1973, Journal of pharmaceutical sciences.

Permeation of hairless mouse skin I: Experimental methods and comparison with human epidermal permeation by alkanols.

G. Flynn, W. Higuchi, H. Durrheim, 1980, Journal of pharmaceutical sciences.

Physicochemical study of percutaneous absorption enhancement by dimethyl sulfoxide: kinetic and thermodynamic determinants of dimethyl sulfoxide mediated mass transfer of alkanols.

G. Flynn, W. Higuchi, T. Kurihara-Bergstrom, 1986, Journal of pharmaceutical sciences.

Physicochemical study of percutaneous absorption enhancement by dimethyl sulfoxide: dimethyl sulfoxide mediation of vidarabine (ara-A) permeation of hairless mouse skin.

G. Flynn, W. Higuchi, T. Kurihara-Bergstrom, 1987, The Journal of investigative dermatology.

Phase volume and partitioning effects on drug delivery from topical emulsions

G. Flynn, S. Y. Hou, 1990 .

Physical model evaluation of topical prodrug delivery--simultaneous transport and bioconversion of vidarabine-5'-valerate III: Permeability differences of vidarabine and n-pentanol in components of hairless mouse skin.

G. Flynn, J. Fox, W. Higuchi, 1980, Journal of Pharmacy and Science.

Mechanisms of topical delivery of liposomally entrapped drugs

N. Weiner, G. Flynn, N. Ho, 1985 .

Hydration and percutaneous absorption IV: influence of hydration on n-alkanol permeation through rat skin; comparison with hairless and Swiss mice.

G. Flynn, C. R. Behl, A. A. El-Sayed, 1983, Journal of pharmaceutical sciences.

Bioequivalence of Topical Dermatological Dosage Forms-Methods of Evaluation of Bioequivalence

H. Maibach, G. Flynn, L. Lesko, 1998, Pharmaceutical Research.

FDA and AAPS Report of the Workshop on Principles and Practices of In Vitro Percutaneous Penetration Studies: Relevance to Bioavailability and Bioequivalence

R. Guy, H. Maibach, G. Flynn, 1987, Pharmaceutical Research.

In Vivo Percutaneous Penetration/Absorption, Washington, D.C., May 1989

R. Guy, H. Maibach, G. Flynn, 1991, Pharmaceutical Research.

Workshop III Report: Scaleup of Liquid and Semisolid Disperse Systems

R. Guy, G. Flynn, L. Lesko, 1994, Pharmaceutical Research.

In vivo percutaneous penetration/absorption

R. Guy, H. Maibach, G. Flynn, 1991 .

Physicochemical characterization of the human nail: permeation pattern for water and the homologous alcohols and differences with respect to the stratum corneum *

G. Flynn, K. A. Walters, J. Marvel, 1983, The Journal of pharmacy and pharmacology.

Bioavailability assessment of topical delivery systems: effect of vehicle evaporation upon in vitro delivery of minoxidil from solution formulations

N. Weiner, G. Flynn, Chiang Chia-Ming, 1989 .

The Molecular Weight Dependence of Nasal Absorption: The Effect of Absorption Enhancers

G. Flynn, G. Amidon, M. Donovan, 1990, Pharmaceutical Research.

Absorption of Polyethylene Glycols 600 Through 2000: The Molecular Weight Dependence of Gastrointestinal and Nasal Absorption

G. Flynn, G. Amidon, M. Donovan, 1990, Pharmaceutical Research.

Transfollicular Drug Delivery

N. Weiner, G. Flynn, C. Ramachandran, 1995, Pharmaceutical Research.

Permeation of mouse skin and silicone rubber membranes by phenols: relationship to in vitro partitioning.

G. Flynn, N. Duraiswamy, N. Ho, 1986, Journal of pharmaceutical sciences.

The Dermal Barrier to Local and Systemic Drug Delivery

G. Flynn, J. Fox, K. Knutson, 1985 .

Some hydrodynamic boundary layer influences on mass transfer coefficients

G. Flynn, E. Williams, G. Amidon, 1984 .

Topical delivery of liposomally encapsulated interferon evaluated in a cutaneous herpes guinea pig model

N. Weiner, G. Flynn, C. Ramachandran, 1989, Antimicrobial Agents and Chemotherapy.

Permeability characteristics of the human nail plate

G. Flynn, K. A. Walters, 1983, International journal of cosmetic science.

Ether-water partitioning and permeability through nude mouse skin in vitro. I. Urea, thiourea, glycerol and glucose

G. Flynn, C. Ackermann, 1987 .

Physicochemical characterization of the human nail: solvent effects on the permeation of homologous alcohols *

G. Flynn, K. A. Walters, J. Marvel, 1985, The Journal of pharmacy and pharmacology.

Penetration of the human nail plate: the effects of vehicle pH on the permeation of miconazole

G. Flynn, K. A. Walters, J. Marvel, 1985, The Journal of pharmacy and pharmacology.

Physicochemical characterization of the human nail: I. Pressure sealed apparatus for measuring nail plate permeabilities.

G. Flynn, K. A. Walters, J. Marvel, 1981, The Journal of investigative dermatology.

Formulation factors affecting release of drug from topical vehicles. II. Effect of solubility on in vitro delivery of a series of n-alkyl p-aminobenzoates.

N. Weiner, G. Flynn, C. Lalor, 1995, Journal of pharmaceutical sciences.

Transdermal Delivery of Bioactive Peptides: The Effect of n-Decylmethyl Sulfoxide, pH, and Inhibitors on Enkephalin Metabolism and Transport

G. Flynn, G. Amidon, Hoo-Kyun Choi, 2004, Pharmaceutical Research.

Percutaneous absorption of corticosteroids: age, site, and skin-sectioning influences on rates of permeation of hairless mouse skin by hydrocortisone.

G. Flynn, C. R. Behl, E. Linn, 1984, Journal of pharmaceutical sciences.

Membrane diffusion. 3. Influence of solvent composition and permeant solubility on membrane transport.

G. Flynn, R. Smith, 1972, Journal of pharmaceutical sciences.

Structural approach to partitioning: Estimation of steroid partition coefficients based upon molecular constitution.

G. Flynn, 1971, Journal of pharmaceutical sciences.

Solvent effects on the harvesting of stratum corneum from hairless mouse skin through adhesive tape stripping in vitro

N. Weiner, G. Flynn, J. Ferry, 1991 .

Membrane diffusion. I. Design and testing of a new multifeatured diffusion cell.

G. Flynn, E. Smith, 1971, Journal of pharmaceutical sciences.

Solubility and Related Physicochemical Properties of Narcotic Analgesics

G. Flynn, Samir D. Roy, 1988, Pharmaceutical Research.

Transdermal Delivery of Narcotic Analgesics: pH, Anatomical, and Subject Influences on Cutaneous Permeability of Fentanyl and Sufentanil

G. Flynn, Gordon L. Flynn, Samir D. Roy, 1990, Pharmaceutical Research.

Inhibition of cell growth and DNA, RNA, and protein synthesis in vitro by fentanyl, sufentanil, and opiate analgesics.

G. Flynn, M. Nassiri, C. Shipman, 1991, Pharmacology & toxicology.

Solubility of nonelectrolytes in polar solvents III: Alkyl p-aminobenzoates in polar and mixed solvents.

S. Yalkowsky, G. Flynn, G. Amidon, 1975, Journal of pharmaceutical sciences.

Solubility of nonelectrolytes in polar solvents.

G L Amidon, S. Yalkowsky, G. Flynn, 1972, Journal of pharmaceutical sciences.

Cholesterol solubility in organic solvents.

W I Higuchi, G. Flynn, W. Higuchi, 1979, Journal of pharmaceutical sciences.

Solubility Behavior of Narcotic Analgesics in Aqueous Media: Solubilities and Dissociation Constants of Morphine, Fentanyl, and Sufentanil

G. Flynn, Samir D. Roy, 1989, Pharmaceutical Research.

Topical and Transdermal Drug Products

H. Maibach, G. Flynn, V. Shah, 2010 .

Percutaneous Delivery of Thalidomide and Its N-Alkyl Analogs

G. Flynn, T. Goosen, C. Goosen, 2002, Pharmaceutical Research.

Age and anatomical site influences on alkanol permeation of skin of the male hairless mouse

G. Flynn, W. Higuchi, N. Ho, 1984 .

Transdermal delivery of narcotic analgesics: comparative metabolism and permeability of human cadaver skin and hairless mouse skin.

G. Flynn, S. Roy, S. Y. Hou, 1994, Journal of pharmaceutical sciences.

Influence of liposomal drug entrapment on percutaneous absorption

N. Weiner, G. Flynn, N. Ho, 1984 .

Properties of adhesive tapes used for stratum corneum stripping

N. Weiner, G. Flynn, J. Ferry, 1991 .

A Solubility and Related Physicochemical Property Comparison of Buprenorphine and Its 3-Alkyl Esters

G. Flynn, R. Woodard, A. Paliwal, 2004, Pharmaceutical Research.

Penetration of minoxidil from ethanol/propylene glycol solutions: effect of application volume and occlusion.

N. Weiner, G. Flynn, S. Tata, 1995, Journal of pharmaceutical sciences.

Factors to be considered in the evaluation of bioavailability and bioequivalence of topical formulations.

G. Flynn, V. Shah, A. Ghanem, 1992, Skin pharmacology : the official journal of the Skin Pharmacology Society.

Scale-up of Adhesive Transdermal Drug Delivery Systems

Mario A. González, G. Flynn, A. Hussain, 1997, Pharmaceutical Research.

Mass transport phenomena and models: theoretical concepts.

S. Yalkowsky, G. Flynn, S H Yalkowsky, 1974, Journal of pharmaceutical sciences.

Percutaneous drug penetration: Choosing candidates for transdermal development

G. Flynn, Gordon L. Flynn, Barbra Stewart, 1988 .

Assessment of Value and Applications of In Vitro Testing of Topical Dermatological Drug Products

G. Flynn, V. Shah, T. Franz, 1999, Pharmaceutical Research.

Controlled transdermal delivery of fentanyl: characterizations of pressure-sensitive adhesives for matrix patch design.

G. Flynn, Saumendu Deb Roy, G. Cleary, 1996, Journal of pharmaceutical sciences.

An Explanation of the Minima in Surface Tension-Log Concentration Profiles

N. Weiner, G. Flynn, 1974 .

Vaginal drug absorption in rhesus monkeys I: development of methodology.

G. Flynn, C. R. Behl, S. Hwang, 1977, Journal of pharmaceutical sciences.

Systems approach to vaginal delivery of drugs II: In situ vaginal absorption of unbranched aliphatic alcohols.

G. Flynn, T. Yotsuyanagi, W. Higuchi, 1976, Journal of pharmaceutical sciences.

Permeation of hydrocortisone and hydrocortisone 21-alkyl esters through silicone rubber membranes — relationship to regular solution solubility behavior

G. Flynn, T. Hagen, 1987 .

Solubility of hydrocortisone in organic and aqueous media: evidence for regular solution behavior in apolar solvents.

G. Flynn, T. Hagen, 1983, Journal of pharmaceutical sciences.

Solubility of organic hydrochlorides.

G. Flynn, G L Flynn, S F Kramer, 1972, Journal of pharmaceutical sciences.

Systems approach to vaginal delivery of drugs III: Simulation studies interfacing steroid release from silicone matrix and vaginal absorption in rabbits.

G. Flynn, W. Higuchi, N. Ho, 1976, Journal of pharmaceutical sciences.

Hydration and percutaneous absorption: I. Influence of hydration on alkanol permeation through hairless mouse skin.

G. Flynn, W. Higuchi, N. Ho, 1980, The Journal of investigative dermatology.

Vaginal drug absorption in the rhesus monkey: Bioavailability method and assessment of estrogens

G. Flynn, W. Higuchi, M. Langworthy, 1979 .

Systems approach to vaginal delivery of drugs I: development of in situ vaginal drug absorption procedure.

G. Flynn, T. Yotsuyanagi, W. Higuchi, 1975, Journal of pharmaceutical sciences.

Permeability of thermally damaged skin III: Influence of scalding temperature on mass transfer of water and n-alkanols across hairless mouse skin

G. Flynn, W. Higuchi, K. A. Walters, 1981 .

Systems approach to vaginal delivery of drugs V: in situ vaginal absorption of 1-alkanoic acids.

G. Flynn, W. Higuchi, N. Ho, 1977, Journal of pharmaceutical sciences.

Systems approach to vaginal delivery of drugs IV: methodology for determination of membrane surface pH.

G. Flynn, W. Higuchi, N. Ho, 1977, Journal of pharmaceutical sciences.

Epidermal Kinetics and Skin Condition: I. Stripping Technique for Quantitating Stratum Corneum Turnover in Hairless Mouse Skin

G. Flynn, S. T. Han, Sie-Ta R. Han, 1989 .

Influence of 1-dodecylazacycloheptan-2-one (Azone) on the topical therapy of cutaneous herpes simplex virus type 1 infection in hairless mice with 2',3'-di-O-acetyl-9-beta-D-arabinofuranosyladenine and 5'-O-valeryl-9-beta-D-arabinofuranosyladenine.

G. Flynn, J. Fox, K. Sugibayashi, 1985, Journal of pharmaceutical sciences.

Topical Delivery of Antiviral Agents: In Vivo / In Vitro Correlations

G. Flynn, W. Higuchi, N. Ho, 1984 .

Absorption Rate Limit Considerations for Oral Phosphate Prodrugs

G. Flynn, J. Leppänen, D. Fleisher, 2003, Pharmaceutical Research.

Importance of chain length on physicochemical and crystalline properties of organic homologs.

S. Yalkowsky, G. Flynn, T. G. Slunick, 1972, Journal of pharmaceutical sciences.

Bioavailability assessment of topical delivery systems: effect of inter-subject variability on relative in vitro deliveries of minoxidil and hydrocortisone from solution and ointment formulations

N. Weiner, G. Flynn, G. J. Szpunar, 1989 .

Solid and Liquid Heat Capacities of n-Alkyl Para-aminobenzoates Near the Melting Point

G. Flynn, S. Neau, 1990, Pharmaceutical Research.

The influence of heat capacity assumptions on the estimation of solubility parameters from solubility data

S. Yalkowsky, G. Flynn, S. Neau, 1989 .

Influence of age on turnover times of normal, ultraviolet-irradiated, and tape-burned hairless mouse skin

G. Flynn, S. T. Han, M. Haberkamp, 1991 .

Correlation and prediction of mass transport across membranes. I. Influence of alkyl chain length on flux-determining properties of barrier and diffusant.

S. Yalkowsky, G. Flynn, S H Yalkowsky, 1972, Journal of pharmaceutical sciences.

Transdermal Delivery of Narcotic Analgesics: Comparative Permeabilities of Narcotic Analgesics Through Human Cadaver Skin

G. Flynn, Gordon L. Flynn, Samir D. Roy, 1989, Pharmaceutical Research.

Factors affecting diazepam infusion: solubility, administration-set composition, and flow rate.

G. Flynn, R. Berardi, N. Mason, 1981, American journal of hospital pharmacy.

Validation of a Flow-Through Diffusion Cell for Use in Transdermal Research

Norman Weiner, N. Weiner, G. Flynn, 1987, Pharmaceutical Research.

Drug Transport from Thin Applications of Topical Dosage Forms: Development of Methodology

N. Weiner, G. Flynn, W. Addicks, 1988, Pharmaceutical Research.

Monooctanoin, a dissolution agent for retained cholesterol bile duct stones: Physical properties and clinical application

G. Flynn, N. LaRusso, R. Maccarty, 1980 .

Membrane diffusion. II. Influence of physical adsorption on molecular flux through heterogeneous dimethylpolysiloxane barriers.

G. Flynn, T. J. Roseman, 1971, Journal of pharmaceutical sciences.

Relative influence of ethanol and propylene glycol cosolvents on deposition of minoxidil into the skin.

N. Weiner, G. Flynn, S. Tata, 1994, Journal of pharmaceutical sciences.

Drug and vehicle deposition from topical applications: use of in vitro mass balance technique with minoxidil solutions.

N. Weiner, G. Flynn, J. Ferry, 1992, Journal of pharmaceutical sciences.

Release of Hydrocortisone from a Cream Matrix: Dependency of Release on Suspension Concentration and Measurement of Solubility and Diffusivity

G. Flynn, V. Shah, L. Abriola, 2001, Pharmaceutical development and technology (Print).

Principles and criteria in the development and optimization of topical therapeutic products.

G. Flynn, V. Shah, W. Higuchi, 1992, Pharmaceutical research.

Principles and criteria in the development and optimization of topical therapeutic products.

G. Flynn, V. Shah, W. Higuchi, 1992, Journal of pharmaceutical sciences.

Permeation of Buprenorphine and Its 3-Alkyl-Ester Prodrugs Through Human Skin

G. Flynn, R. Woodard, A. Paliwal, 1996, Pharmaceutical Research.

Permeation of hairless mouse skin II: membrane sectioning techniques and influence on alkanol permeabilities.

G. Flynn, W. Higuchi, H. Dürrheim, 1981, Journal of pharmaceutical sciences.

Formulation factors affecting release of drug from topical formulations. 1. Effect of emulsion type upon in vitro delivery of ethyl p-aminobenzoate.

N. Weiner, G. Flynn, C. Lalor, 1994, Journal of pharmaceutical sciences.

Physicochemical Characterization and Solubility Analysis of Thalidomide and Its N-Alkyl Analogs

Timothy J. Laing, G. Flynn, T. Goosen, 2004, Pharmaceutical Research.

Cutaneous and Transdermal Delivery—Processes and Systems of Delivery

G. Flynn, 1996 .

General influence of physicochemical properties on drug-receptor combination.

N. Weiner, S. Yalkowsky, G. Flynn, 1974, Journal of Pharmacy and Science.

Transport of alkyl homologs across synthetic and biological membranes: a new model for chain length-activity relationships.

S. Yalkowsky, G. Flynn, 1973, Journal of pharmaceutical sciences.

Permeability of Thermally Damaged Skin: I. Immediate Influences of 60°C Scalding on Hairless Mouse Skin

G. Flynn, W. Higuchi, N. Ho, 1980 .

Effects of alkyl chain length on biological activity: alkyl p-aminobenzoate-induced narcosis in goldfish.

S. Yalkowsky, G. Flynn, T. G. Slunick, 1974, Journal of pharmaceutical sciences.

General Introduction and Conceptual Differentiation of Topical and Transdermal Drug Delivery Systems

G. Flynn, 1993 .

Topical drug absorption and topical pharmaceutical systems

G. Flynn, 1990 .

A mathematical model to describe drug release from thin topical applications

N. Weiner, G. Flynn, R. Curl, 1989 .

Bioavailability assessment of topical delivery systems: in vitro delivery of minoxidil from prototypical semi-solid formulations

N. Weiner, G. Flynn, W. Addicks, 1989 .

Total mathematical resolution of diffusion layer control of barrier flux.

S. Yalkowsky, G. Flynn, O. S. Carpenter, 1972, Journal of pharmaceutical sciences.

Permeation of water contaminative phenols through hairless mouse skin

G. Flynn, N. Ho, A. Huq, 1986, Archives of environmental contamination and toxicology.

In vivo percutaneous penetration / absorption Sponsored by the American Association of Pharmaceutical Scientists

R. Guy, H. Maibach, G. Flynn, 2002 .

Hydration and percutaneous absorption III: Influences of stripping and scalding on hydration alteration of the permeability of hairless mouse skin to water and n-alkanols.

G. Flynn, W. Higuchi, N. Ho, 1982, Journal of pharmaceutical sciences.

Percutaneous absorption and dermal delivery of cyclosporin A.

G. Flynn, G. Amidon, H. K. Choi, 1995, Journal of pharmaceutical sciences.

Topical ciclosporin for psoriasis: in vitro skin penetration and clinical study.

N. Weiner, G. Flynn, T. Annesley, 1988, Skin pharmacology : the official journal of the Skin Pharmacology Society.

Correlation and prediction of mass transport across membranes. II. Influence of vehicle polarity on flux from solutions and suspensions.

S. Yalkowsky, G. Flynn, 1974, Journal of pharmaceutical sciences.

Effect of minoxidil concentration on the deposition of drug and vehicle into the skin

N. Weiner, G. Flynn, J. Ferry, 1993 .

Influence of Physico-Chemical Properties of Drug and System on Release of Drugs from Inert Matrices

G. Flynn, 1974 .

Topical Drug Delivery from Thin Applications: Theoretical Predictions and Experimental Results

N. Weiner, G. Flynn, E. Topp, 1990, Pharmaceutical Research.

Technique for preparing appendage-free skin (scar) on hairless mouse.

G. Flynn, C. Pierson, A. Wittkowsky, 1981, Journal of pharmaceutical sciences.

Transdermal prodrug concepts: permeation of buprenorphine and its alkyl esters through hairless mouse skin and influence of vehicles.

G. Flynn, A. Stinchcomb, H. Imoto, 1996, Biological and Pharmaceutical Bulletin.

Factors influencing solvolysis of corticosteroid-21-phosphate esters.

G. Flynn, D. J. Lamb, 1970, Journal of pharmaceutical sciences.

Etorphine Is an Opiate Analgesic Physicochemically Suited to Transdermal Delivery

Hoo-Kyun Choi, G. Flynn, Hoo-Kyun Choi, 1992, Pharmaceutical Research.

Systemic uptake and clearance of chloroform by hairless rats following dermal exposure. I. Brief exposure to aqueous solutions.

G. Flynn, J. Mcdougal, M. S. Islam, 1995, Risk analysis : an official publication of the Society for Risk Analysis.

Monooctanoin, a dissolution agent for retained cholesterol bile duct stones: physical properties and clinical application.

G. Flynn, N. LaRusso, R. Maccarty, 1980, Gastroenterology.

Permeation of skin and eschar by antiseptics I: baseline studies with phenol.

G. Flynn, W. Higuchi, N. Ho, 1983, Journal of Pharmacy and Science.

Permeation of skin and eschar by antiseptics II: influence of controlled burns on the permeation of phenol.

G. Flynn, W. Higuchi, N. Ho, 1983, Journal of pharmaceutical sciences.

Bioequivalence of Topical Dermatological Dosage Forms – Methods of Evaluation of Bioequivalence

Howard I. Maibach, Charles Bon, Vinod P. Shah, 1998, Skin Pharmacology and Physiology.

Influences of 1-dodecylazacycloheptan-2-one on permeation of membranes by weak electrolytes. 1. Theoretical analysis of weak electrolyte diffusion through membranes and studies involving silicone rubber membranes.

G. Flynn, S. Y. Hou, 1997, Journal of pharmaceutical sciences.

Follicular (Pilosebaceous Unit) Deposition and Pharmacological Behavior of Cimetidine as a Function of Formulation

N. Weiner, G. Flynn, L. M. Lieb, 1994, Pharmaceutical Research.

Chemical Stabilities and Biological Activities of Thalidomide and Its N-Alkyl Analogs

G. Flynn, T. Goosen, C. Goosen, 2002, Pharmaceutical Research.

Principles and Criteria in the Development and Optimization of Topical Therapeutic Products

G. Flynn, V. Shah, W. Higuchi, 1992, Pharmaceutical Research.

Analysis of diffusion through concentric right circular cylinders and concentric spheres.

G. Flynn, W. Higuchi, N. Ho, 1976, Journal of pharmaceutical sciences.