I. König

I. König, P. Reinke, D. Stippel, 2017, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

Passive rotary dynamic sitting at the workplace by office-workers with lumbar pain: a randomized multicenter study.

I. König, A. Ziegler, M. Lengsfeld, 2007, The spine journal : official journal of the North American Spine Society.

Sepsis syndrome and death in trauma patients are associated with variation in the gene encoding tumor necrosis factor*

I. König, A. Ziegler, P. Vos, 2008, Critical care medicine.

Machine learning and data mining in complex genomic data—a review on the lessons learned in Genetic Analysis Workshop 19

I. König, E. Holzinger, Hsin-Chou Yang, 2016, BMC Genetics.

Predicting functional outcome and survival after acute ischemic stroke

I. König, A. Ziegler, H. Diener, 2002, Journal of Neurology.

New susceptibility locus for coronary artery disease on chromosome 3q22.3

Benjamin J. Wright, A. Peters, P. Deloukas, 2009, Nature Genetics.

Genome-wide association study identifies a new locus for coronary artery disease on chromosome 10p11.23.

C. Gieger, A. Peters, C. Loley, 2011, European heart journal.

Large-scale association analysis identifies new risk loci for coronary artery disease

J. Danesh, R. Collins, D. Absher, 2013 .

A comprehensive 1000 Genomes-based genome-wide association meta-analysis of coronary artery disease

J. Danesh, R. Collins, C. Gieger, 2016 .

Genetically determined height and coronary artery disease.

J. Danesh, R. Collins, T. Assimes, 2015, The New England journal of medicine.

Association analyses of 249,796 individuals reveal eighteen new loci associated with body mass index

Henrik, Tanya M. Teslovich, Jennie, 2012 .

Risky behaviors and Parkinson disease

I. König, C. Lill, C. Klein, 2019, Neurology.

A Mendelian randomization study of glycemic and anthropometric traits and Parkinson’s disease

I. König, N. Brüggemann, Manu Sharma, 2020, bioRxiv.

Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease

Thomas W. Mühleisen, Benjamin J. Wright, C. Gieger, 2011, Nature Genetics.

What is precision medicine?

I. König, G. Hansen, E. von Mutius, 2017, European Respiratory Journal.

Spinocerebellar ataxia type 5

I. König, A. Ziegler, J. Dichgans, 2004, Neurology.

A prospective evaluation of psychosocial outcomes following ear reconstruction with rib cartilage in microtia.

I. König, H. Frenzel, B. Wollenberg, 2010, Journal of plastic, reconstructive & aesthetic surgery : JPRAS.

Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study

John Spertus, Markus Perola, Eric Boerwinkle, 2012, The Lancet.

Role of ethnicity on the association of MAPT H1 haplotypes and subhaplotypes in Parkinson's disease

I. König, P. Vieregge, V. Kostic, 2007, European Journal of Human Genetics.

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

Christian Gieger, Jianxin Shi, Inês Barroso, 2013, Nature Genetics.

Inactivating mutations in NPC1L1 and protection from coronary heart disease.

John Spertus, Thomas Meitinger, Joshua C Denny, 2014, The New England journal of medicine.

SNP-Based Analysis of Genetic Substructure in the German Population

Thomas Meitinger, Kathryn Roeder, Michael Krawczak, 2006, Human Heredity.

Group Sequential Study Designs in Genetic-Epidemiological Case-Control Studies

Andreas Ziegler, Inke R. König, I. König, 2003, Human Heredity.

Statistical Genetics — Present and Future

I. König, A. Ziegler, H. Schäfer, 2003 .

Presidential address: Six open questions to genetic epidemiologists

Inke R König, I. König, 2019, Genetic epidemiology.

Evaluating diagnostic accuracy of genetic profiles in affected offspring families

Andreas Ziegler, Inke R König, Jörg Hager, 2010, Statistics in medicine.

Polymorphisms of the NADPH Oxidase p22phox Gene in a Caucasian Population with Intracranial Aneurysms

I. König, A. Ziegler, G. Schackert, 2003, Cerebrovascular Diseases.

Can we predict cognitive decline after initial diagnosis of multiple sclerosis? Results from the German National early MS cohort (KKNMS)

I. König, F. Paul, U. Ziemann, 2018, Journal of Neurology.

Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure

Christian Gieger, Jingyuan Fu, Thomas Meitinger, 2011, Nature Genetics.

Repeated Replication and a Prospective Meta-Analysis of the Association Between Chromosome 9 p 21 . 3 and Coronary Artery Disease

Ludwig A Hothorn, Nilesh J Samani, Andreas Ziegler, 2008 .

The large non-coding RNA ANRIL, which is associated with atherosclerosis, periodontitis and several forms of cancer, regulates ADIPOR1, VAMP3 and C11ORF10.

Philip Rosenstiel, Stefan Schreiber, Robert Häsler, 2013, Human molecular genetics.

Two Models for Outcome Prediction

A Ziegler, S J Pöppl, I R König, 2006, Methods of Information in Medicine.

Brain Regional Differences in Hexanucleotide Repeat Length in X-Linked Dystonia-Parkinsonism Using Nanopore Sequencing

I. König, N. Brüggemann, C. Klein, 2021, Neurology: Genetics.

Statistical learning approaches in the genetic epidemiology of complex diseases

Marvin N. Wright, A. Boulesteix, I. König, 2019, Human Genetics.

A roadmap to multifactor dimensionality reduction methods

Kristel Van Steen, Jestinah M. Mahachie John, Damian Gola, 2015, Briefings Bioinform..

Cytokine gene polymorphisms in allergiccontact dermatitis

I. König, A. Ziegler, A. Schnuch, 2003, Contact dermatitis.

Polymorphisms in the Mitochondrial Genome Are Associated With Bullous Pemphigoid in Germans

I. König, J. Erdmann, W. Lieb, 2019, Front. Immunol..

Correction: Lifelong Reduction of LDL-Cholesterol Related to a Common Variant in the LDL-Receptor Gene Decreases the Risk of Coronary Artery Disease—A Mendelian Randomisation Study

C. Gieger, F. Kronenberg, A. Peters, 2008, PLoS ONE.

Identification of interactions using model-based multifactor dimensionality reduction

I. König, D. Gola, 2016, BMC Proceedings.

Analysis of the base excision repair genes MTH1, OGG1 and MUTYH in patients with squamous oral carcinomas.

I. König, A. Ziegler, H. Schackert, 2007, Oral oncology.

Combined-modality 125J-seed-brachytherapy, external beam radiation and androgen deprivation therapy of unfavorable-risk prostate cancer: report of outcomes and side-effects

I. König, A. Boehle, K. Katic, 2019, World Journal of Urology.

Comparison of outcome endpoints in intermediate- and high-risk prostate cancer after combined-modality radiotherapy.

I. König, A. Boehle, K. Katic, 2019, Brachytherapy.

Genome-wide exploration identifies sex-specific genetic effects of alleles upstream NPY to increase the risk of severe periodontitis in men.

C. Gieger, I. König, W. Lieb, 2014, Journal of clinical periodontology.

TNF polymorphisms in psoriasis: association of psoriatic arthritis with the promoter polymorphism TNF*-857 independent of the PSORS1 risk allele.

I. König, A. Reis, K. Reich, 2007, Arthritis and rheumatism.

Early Skin-to-Skin Contact Does Not Affect Cerebral Tissue Oxygenation in Preterm Infants <32 Weeks of Gestation

I. König, W. Göpel, C. Härtel, 2022, Children.

The effect of less invasive surfactant administration on cerebral oxygenation in preterm infants

I. König, W. Göpel, C. Härtel, 2020, Acta paediatrica.

The psychosocial consequences of reconstruction of severe ear defects or third-degree microtia with rib cartilage.

I. König, H. Frenzel, A. Steffen, 2008, Aesthetic surgery journal.

The Use of Vitamin K2 in Patients With Parkinson's Disease and Mitochondrial Dysfunction (PD-K2): A Theranostic Pilot Study in a Placebo-Controlled Parallel Group Design

I. König, N. Brüggemann, S. Schmid, 2021, Frontiers in Neurology.

Inferior vena cava ultrasound in acute decompensated heart failure: design rationale of the CAVA‐ADHF‐DZHK10 trial

I. König, H. Thiele, M. Borggrefe, 2020, ESC heart failure.

Age at Onset of LRRK2 p.Gly2019Ser Is Related to Environmental and Lifestyle Factors

I. König, M. Farrer, C. Klein, 2020, Movement disorders : official journal of the Movement Disorder Society.

Health of VLBW infants in Germany at five years of age: What do parents describe?

I. König, W. Göpel, J. Spiegler, 2017, Early human development.

Radiosurgery for ventricular tachycardia: preclinical and clinical evidence and study design for a German multi-center multi-platform feasibility trial (RAVENTA)

I. König, V. Budach, A. Schweikard, 2020, Clinical Research in Cardiology.

Interleukin-6-174-genotype, sepsis and cerebral injury in very low birth weight infants

I. König, W. Göpel, H. Segerer, 2006, Genes and Immunity.

Predicting recovery after intracerebral hemorrhage – An external validation in patients from controlled clinical trials

I. König, A. Ziegler, R. Sacco, 2009, Journal of Neurology.

Development and reliability of the histological THROMBEX-classification rule for thrombotic emboli of acute ischemic stroke patients

I. König, G. Royl, F. Roessler, 2021, Neurological Research and Practice.

No Association of Coronary Artery Disease with X-Chromosomal Variants in Comprehensive International Meta-Analysis

R. Collins, T. Assimes, E. Mihailov, 2016, Scientific Reports.

Impact of guideline changes on adoption of hypofractionation and breast cancer patient characteristics in the randomized controlled HYPOSIB trial

I. König, S. Dinges, J. Dunst, 2020, Strahlentherapie und Onkologie.

Efficacy of Bifidobacterium animalis subsp. lactis (BB-12), B. infantis and Lactobacillus acidophilus (La-5) probiotics to prevent gut dysbiosis in preterm infants of 28+0–32+6 weeks of gestation: a randomised, placebo-controlled, double-blind, multicentre trial: the PRIMAL Clinical Study Protocol

P. Bork, I. König, W. Göpel, 2019, BMJ Open.

Preferred reporting items of systematic review and meta-analyses: the PRISMA statement

I. König, G. Antes, A. Ziegler, 2011 .

Tissue Destruction in Bullous Pemphigoid Can Be Complement Independent and May Be Mitigated by C5aR2

I. König, D. Zillikens, J. Köhl, 2018, Front. Immunol..

Comparison of Six Different Allergen Extracts for Subcutaneous Specific Immunotherapy in Children: An Open-Labelled, Prospective, Controlled Observational Trial

I. König, B. Niggemann, M. Kopp, 2019, International Archives of Allergy and Immunology.

Rhinovirus infections change DNA methylation and mRNA expression in children with asthma

I. König, K. Rabe, A. Franke, 2018, PloS one.

Risky behaviors and Parkinson’s disease: A Mendelian randomization study in up to 1 million study participants

I. König, C. Lill, C. Klein, 2018, bioRxiv.

The “Shiny and Thick High Heel Sign”

I. König, J. Küchler, C. Ditz, 2021, Clinical Neuroradiology.

Pregnancy risk factors for very premature delivery: what role do hypertension, obesity and diabetes play?

I. König, W. Göpel, B. Bohnhorst, 2013, Archives of Gynecology and Obstetrics.

Applications of AI / ML approaches in cardiovascular medicine : A systematic review 1 with recommendations 2

I. König, T. Friede, M. Bahls, 2021 .

Association of angiotensin-converting enzyme 2 (ACE2) gene polymorphisms with parameters of left ventricular hypertrophy in men

I. König, J. Erdmann, C. Hengstenberg, 2005, Journal of Molecular Medicine.

Effects of common atopy-associated amino acid substitutions in the IL-4 receptor alpha chain on IL-4 induced phenotypes

I. König, A. Ziegler, H. Hackstein, 2005, Immunogenetics.

IgA+ memory B-cells are significantly increased in patients with asthma and small airway dysfunction

I. König, D. DeLuca, H. Watz, 2022, European Respiratory Journal.

Preformed Donor-Specific HLA Antibodies in Living and Deceased Donor Transplantation: A Multicenter Study.

I. König, A. Rahmel, P. Reinke, 2019, Clinical journal of the American Society of Nephrology : CJASN.

Evaluation of Individualized Multi‐Disciplinary Inpatient Treatment for Functional Movement Disorders

I. König, G. Ebersbach, A. Münchau, 2021, Movement disorders clinical practice.

Genome‐wide association study identifies new susceptibility loci for cutaneous lupus erythematosus

J. Kere, I. König, A. Ziegler, 2015, Experimental dermatology.

Alcohol and colorectal cancer: the role of alcohol dehydrogenase 1C polymorphism.

I. König, S. Mueller, F. Stickel, 2009, Alcoholism, clinical and experimental research.

Investigation of the DCDC2 intron 2 deletion/compound short tandem repeat polymorphism in a large German dyslexia sample

M. Nöthen, J. Kere, I. König, 2008, Psychiatric genetics.

Genotype‐phenotype relations for the Parkinson's disease genes SNCA, LRRK2, VPS35: MDSGene systematic review

I. König, K. Lohmann, C. Lill, 2018, Movement disorders : official journal of the Movement Disorder Society.

Identifying rare variants from exome scans: the GAW17 experience

R. Cantor, N. Laird, I. König, 2011, BMC proceedings.

Association of allergic contact dermatitis with a promoter polymorphism in the IL16 gene.

I. König, A. Ziegler, A. Schnuch, 2003, The Journal of allergy and clinical immunology.

Evaluation of Aerobic Exercise Intensity in Patients with Coronary Artery Disease and Type 2 Diabetes Mellitus

I. König, M. Schütt, B. Schwaab, 2020, Journal of clinical medicine.

Biostatistical Aspects of Genome‐Wide Association Studies

John R Thompson, Andreas Ziegler, Inke R König, 2008, Biometrical journal. Biometrische Zeitschrift.

Discordant Monozygotic Parkinson Disease Twins: Role of Mitochondrial Integrity

I. König, K. Lohmann, P. Urban, 2020, Annals of neurology.

Identification of representative trees in random forests based on a new tree-based distance measure

I. König, A. Westenberger, Björn-Hergen Laabs von Holt, 2022, bioRxiv.

Biological effects of the PINK1 c.1366C>T mutation: implications in Parkinson disease pathogenesis

I. König, F. Binkofski, H. Siebner, 2007, Neurogenetics.

Mitochondrial damage-associated inflammation highlights biomarkers in PRKN/PINK1 parkinsonism

I. König, P. Rosenstiel, K. Wasner, 2020, Brain : a journal of neurology.

Relationship of Genotype, Phenotype, and Treatment in Dopa‐Responsive Dystonia: MDSGene Review

I. König, H. Huppertz, N. Brüggemann, 2021, Movement disorders : official journal of the Movement Disorder Society.

Influence of L-dopa on subtle motor signs in heterozygous Parkin- and PINK1 mutation carriers.

I. König, N. Brüggemann, K. Lohmann, 2017, Parkinsonism & related disorders.

Variations in the genes encoding the peroxisome proliferator-activated receptors α and γ in psoriasis

I. König, A. Ziegler, R. Kaiser, 2004, Archives of Dermatological Research.

Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease.

J. Danesh, M. Waldenberger, A. Reiner, 2016, The New England journal of medicine.

A Genome-Wide Association Study for Coronary Artery Disease Identifies a Novel Susceptibility Locus in the Major Histocompatibility Complex

Nilesh J Samani, Muredach P Reilly, Jeanette Erdmann, 2012, Circulation. Cardiovascular genetics.

A Genome-Wide Association Study Identifies LIPA as a Susceptibility Gene for Coronary Artery Disease

Olli Saarela, Frank Kee, Kaisa Silander, 2011, Circulation. Cardiovascular genetics.

Sex in basic research: concepts in the cardiovascular field.

I. König, V. Regitz-Zagrosek, J. Erdmann, 2017, Cardiovascular research.

Genetic Predisposition to Higher Blood Pressure Increases Coronary Artery Disease Risk

Michael J Pencina, Eric Boerwinkle, Themistocles L Assimes, 2013, Hypertension.

Variations in the genes encoding the peroxisome proliferator-activated receptors alpha and gamma in psoriasis.

I. König, A. Ziegler, R. Kaiser, 2004, Archives of dermatological research.

Genotype‐Phenotype Relations for the Parkinson's Disease Genes Parkin, PINK1, DJ1: MDSGene Systematic Review

I. König, K. Lohmann, L. Bertram, 2018, Movement disorders : official journal of the Movement Disorder Society.

Identification of representative trees in random forests based on a new tree-based distance measure

I. König, A. Westenberger, Björn-Hergen Laabs von Holt, 2022, bioRxiv.

Systematic review of Mendelian randomization studies on Parkinson’s disease

I. König, A. Caliebe, F. Del Greco M, 2022, Medizinische Genetik : Mitteilungsblatt des Berufsverbandes Medizinische Genetik e.V.

Impact of Anesthesia Strategy and Valve Type on Clinical Outcomes After Transcatheter Aortic Valve Replacement.

Astrid E. Berggreen, I. König, H. Thiele, 2021, Journal of the American College of Cardiology.

Evaluating predictive biomarkers for a binary outcome with linear versus logistic regression – Practical recommendations for the choice of the model

I. König, A. Ziegler, M. Schwaninger, 2018, bioRxiv.

Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants

Alberto Piazza, William Matthai, Flora Peyvandi, 2009, Nature Genetics.

A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium

Christian Gieger, Uwe Völker, Mario Falchi, 2009, Nature Genetics.

A survey of genome-wide association studies, polygenic scores and UK Biobank highlights resources for autoimmune disease genetics

I. König, H. Busch, I. Wohlers, 2022, Frontiers in Immunology.

Association of angiotensin-converting enzyme 2 (ACE2) gene polymorphisms with parameters of left ventricular hypertrophy in men. Results of the MONICA Augsburg echocardiographic substudy.

I. König, J. Erdmann, C. Hengstenberg, 2006, Journal of molecular medicine.

Comprehension of the description of side effects in drug information leaflets: a survey of doctors, pharmacists and lawyers.

I. König, A. Ziegler, Anka Hadlak, 2013, Deutsches Arzteblatt international.

Genome editing in induced pluripotent stem cells rescues TAF1 levels in X‐linked dystonia‐parkinsonism

I. König, N. Brüggemann, A. Rolfs, 2018, Movement disorders : official journal of the Movement Disorder Society.

Genetic Polymorphisms of Hemostasis Genes and Primary Outcome of Very Low Birth Weight Infants

I. König, W. Göpel, H. Segerer, 2006, Pediatrics.

Association of the T8590C Polymorphism of CYP4A11 With Hypertension in the MONICA Augsburg Echocardiographic Substudy

I. König, H. Hense, J. Erdmann, 2005, Hypertension.

' s response to reviews Title : TGFB 1 genetic polymorphisms and coronary heart disease risk : a meta-analysis

I. König, J. Boer, E. Feskens, 2011 .

Lack of Association Between the MEF2A Gene and Myocardial Infarction Genetics

I. König, A. Ziegler, J. Erdmann, 2008 .

Lack of Association Between the MEF 2 A Gene and Myocardial Infarction

I. König, A. Ziegler, J. Erdmann, 2007 .

Novel genetic variation of human interleukin-21 receptor is associated with elevated IgE levels in females

I. König, H. Hackstein, G. Bein, 2003, Genes and Immunity.

Extracorporeal Shock Wave Therapy in the Treatment of Lateral Epicondylitis: A Randomized Multicenter Trial

M. Loew, I. König, A. Betthäuser, 2002, The Journal of bone and joint surgery. American volume.

Manganese superoxide dismutase (MnSOD) polymorphism, alcohol, cigarette smoking and risk of oesophageal cancer.

I. König, N. Homann, L. Sun, 2009, Alcohol and alcoholism.

A Mendelian randomization study investigating the causal role of inflammation on Parkinson’s disease

I. König, L. Foco, C. Klein, 2022, Brain : a journal of neurology.

Comparison of newer generation self-expandable vs. balloon-expandable valves in transcatheter aortic valve implantation: the randomized SOLVE-TAVI trial.

I. König, H. Thiele, H. Ince, 2020, European heart journal.

General Versus Local Anesthesia With Conscious Sedation in Transcatheter Aortic Valve Implantation

Astrid E. Berggreen, I. König, H. Thiele, 2020, Circulation.

Predicting Long-Term Outcome After Acute Ischemic Stroke: A Simple Index Works in Patients From Controlled Clinical Trials

Christian Weimar, Andreas Ziegler, Inke R König, 2008, Stroke.

On Confidence Intervals for Genotype Relative Risks and Attributable Risks from Case Parent Trio Designs for Candidate-Gene Studies

I. König, A. Ziegler, A. Philippi, 2005, Human Heredity.

Sample Size Calculations for Controlled Clinical Trials Using Generalized Estimating Equations (GEE)

I. König, J. Rochon, G. Dahmen, 2004, Methods of Information in Medicine.

Genetic Regulation of Serum Phytosterol Levels and Risk of Coronary Artery Disease

C. Gieger, I. König, N. Samani, 2010, Circulation. Cardiovascular genetics.

Insomnia affects patient‐reported outcome in sleep apnea treated with hypoglossal nerve stimulation

I. König, E. Ebner, A. Steffen, 2022, Laryngoscope investigative otolaryngology.

Spectrum of binge eating symptomatology in patients treated with clozapine and olanzapine

I. König, J. Hebebrand, H. Remschmidt, 2003, Journal of Neural Transmission.

Genetic Distance and Mapping Functions

I. König, A. Ziegler, 2006 .

Compound effect of PHOX2B and RET gene variants in congenital central hypoventilation syndrome combined with Hirschsprung disease

I. König, A. Ziegler, H. Schackert, 2008, American journal of medical genetics. Part A.

Genetic Association Study Identifies HSPB7 as a Risk Gene for Idiopathic Dilated Cardiomyopathy

I. König, L. Fauchier, V. Regitz-Zagrosek, 2010, PLoS genetics.

FRET–CLSM and double-labeling indirect immunofluorescence to detect close association of proteins in tissue sections

I. König, W. Kummer, C. Arens, 2006, Laboratory Investigation.

Large-Scale Gene-Centric Analysis Identifies Novel Variants for Coronary Artery Disease

Simon C. Potter, Thomas W. Mühleisen, Benjamin J. Wright, 2011, PLoS genetics.

Electric field aspects in hypoglossal nerve stimulation for obstructive sleep apnea: A bilateral electrophysiological evaluation of unilateral electrode configuration changes.

I. König, N. Brüggemann, A. Steffen, 2022, Journal of sleep research.

The commercial genetic testing landscape for Parkinson's disease.

I. König, C. Blauwendraat, M. Farrer, 2021, Parkinsonism & related disorders.

Sonothrombolysis With Transcranial Color-Coded Sonography and Recombinant Tissue-Type Plasminogen Activator in Acute Middle Cerebral Artery Main Stem Occlusion: Results From a Randomized Study

I. König, G. Seidel, J. Eggers, 2008, Stroke.

Lifelong Reduction of LDL-Cholesterol Related to a Common Variant in the LDL-Receptor Gene Decreases the Risk of Coronary Artery Disease—A Mendelian Randomisation Study

C. Gieger, F. Kronenberg, A. Peters, 2008, PloS one.

Reply: Ovarian response and its prediction are relevant.

I. König, M. Scheinhardt, G. Griesinger, 2019, Human reproduction.

Self-examination low-cost full-field OCT (SELFF-OCT) for patients with various macular diseases

I. König, D. Theisen-Kunde, C. Ehlken, 2020, Graefe's Archive for Clinical and Experimental Ophthalmology.

Do little interactions get lost in dark random forests?

Marvin N. Wright, I. König, A. Ziegler, 2016, BMC Bioinformatics.

Coffee, smoking and aspirin are associated with age at onset in idiopathic Parkinson’s disease

I. König, C. Klein, J. Trinh, 2022, Journal of Neurology.

Biological, Clinical, and Population Relevance of 95 Loci for Blood Lipids

Tanya M. Teslovich, Y. J. Kim, M. Rieder, 2010, Nature.

Brief review of regression‐based and machine learning methods in genetic epidemiology: the Genetic Analysis Workshop 17 experience

Abhijit Dasgupta, Joan E Bailey-Wilson, James D Malley, 2011, Genetic epidemiology.

Allelic and copy-number variations of FcγRs affect granulocyte function and susceptibility for autoimmune blistering diseases.

I. König, W. Lieb, S. Möller, 2015, Journal of autoimmunity.

The revival of the Gini importance?

Stefano Nembrini, Marvin N. Wright, Inke R. König, 2018, Bioinform..

Bullous pemphigoid and cancer in Taiwan

I. König, C. Hammers, 2019, The British journal of dermatology.

Prospective study in bullous pemphigoid: association of high serum anti‐BP180 IgG levels with increased mortality and reduced Karnofsky score

H. Williams, I. König, D. Zillikens, 2018, The British journal of dermatology.

EDITOR Comments on ‘Practical experiences on the necessity of external validation’

A Ziegler, J D Malley, I R König, 2008 .

Incidence of pemphigoid diseases in Northern Germany in 2016 – first data from the Schleswig‐Holstein Registry of Autoimmune Bullous Diseases

I. König, D. Zillikens, A. Katalinic, 2021, Journal of the European Academy of Dermatology and Venereology : JEADV.

Identification of two novel bullous pemphigoid- associated alleles, HLA-DQA1*05:05 and -DRB1*07:01, in Germans

W. Peitsch, I. König, J. Erdmann, 2021, Orphanet Journal of Rare Diseases.

Serum autoantibody reactivity in bullous pemphigoid is associated with neuropsychiatric disorders and the use of antidiabetics and antipsychotics: a large, prospective cohort study

I. König, D. Zillikens, M. Worm, 2022, Journal of the European Academy of Dermatology and Venereology : JEADV.

Genetic Determinants of Circulating Sphingolipid Concentrations in European Populations

Thomas Meitinger, Gerd Schmitz, Igor Rudan, 2009, PLoS genetics.

Effect of ultrasound on thrombolysis of middle cerebral artery occlusion

I. König, G. Seidel, J. Eggers, 2003, Annals of neurology.

Overview of random forest methodology and practical guidance with emphasis on computational biology and bioinformatics

Anne-Laure Boulesteix, Silke Janitza, Jochen Kruppa, 2012, WIREs Data Mining Knowl. Discov..

Performance of prognostic modelling of high and low ovarian response to ovarian stimulation for IVF

I. König, M. Scheinhardt, G. Griesinger, 2018, Human reproduction.

Edinburgh Research Explorer Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function

Tom R. Gaunt, Andrew D. Johnson, Nicholette D. Palmer, 2022 .

Population‐Based Association and Gene by Environment Interactions in Genetic Analysis Workshop 18

Charalampos Papachristou, Glen A Satten, Inke R König, 2014, Genetic epidemiology.

Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis

Judy H. Cho, Nadezhda T. Doncheva, O. Andreassen, 2013, Nature Genetics.

Genetic evidence of assortative mating in humans

Tanya M. Teslovich, Ross M. Fraser, Brendan P. Zietsch, 2017, Nature Human Behaviour.

Lack of Association Between the Trp 719 Arg Polymorphism in Kinesin-Like Protein-6 and Coronary Artery Disease in 19 Case-Control

Alexander F. Wilson, A. F. Wilson, D. Absher, 2017 .

Protein-6 and Coronary Artery Disease in 19 Case-Control Studies Lack of Association Between the Trp719Arg Polymorphism in Kinesin-Like

Alexander F. Wilson, A. F. Wilson, D. Absher, 2012 .

P Lack of Association Between the Trp 719 Arg Polymorphism in Kinesin-Like Protein-6 and Coronary Artery Disease in 19 Case-Control Studies

Alexander F. Wilson, A. F. Wilson, D. Absher, 2010 .

Polymorphisms in the human surfactant protein-D (SFTPD) gene: strong evidence that serum levels of surfactant protein-D (SP-D) are genetically influenced

I. König, A. Ziegler, L. Gortner, 2005, Immunogenetics.

Variations in the peroxisome proliferator-activated receptor-γ gene and melanoma risk

C. Berking, I. König, A. Ziegler, 2007 .

Assessment of transmission distortion on chromosome 6p in healthy individuals using tagSNPs

I. König, P. Schlattmann, A. Ziegler, 2009, European Journal of Human Genetics.

Promoter polymorphisms of the genes encoding tumor necrosis factor-alpha and interleukin-1beta are associated with different subtypes of psoriasis characterized by early and late disease onset.

I. König, A. Ziegler, K. Reich, 2002, The Journal of investigative dermatology.

Data mining, neural nets, trees — Problems 2 and 3 of Genetic Analysis Workshop 15

Xin Li, Jing Li, Dumitru Brinza, 2007, Genetic epidemiology.

Shared Genetic Susceptibility to Ischemic Stroke and Coronary Artery Disease: A Genome-Wide Analysis of Common Variants

Pankaj Sharma, Sudha Seshadri, Cathie Sudlow, 2014, Stroke.

Assessment of Imputation Quality: Comparison of Phasing and Imputation Algorithms in Real Data

I. König, D. Gola, Katharina Stahl, 2021, Frontiers in Genetics.

How to Include Chromosome X in Your Genome‐Wide Association Study

Andreas Ziegler, Jeanette Erdmann, Christina Loley, 2014, Genetic epidemiology.

Rare Occurrence of PHOX2b Mutations in Sporadic Neuroblastomas

I. König, H. Schackert, R. Kappler, 2008, Journal of pediatric hematology/oncology.

Bilateral subthalamic stimulation in Parkin and PINK1 parkinsonism

G. Deuschl, A. Lozano, I. König, 2008, Neurology.

Genotype–Phenotype Relations for Isolated Dystonia Genes: MDSGene Systematic Review

I. König, K. Lohmann, C. Klein, 2021, Movement disorders : official journal of the Movement Disorder Society.

The role of genetic variation of human metabolism for BMI, mental traits and mental disorders

I. König, I. Heid, R. Adan, 2018, Molecular metabolism.

Coding variation in ANGPTL4, LPL, and SVEP1 and the risk of coronary disease

Dermot F. Reilly, J. Danesh, M. Waldenberger, 2018 .

Risk estimation and risk prediction using machine-learning methods

I. König, A. Ziegler, J. Kruppa, 2012, Human Genetics.

Identifying genetic modifiers of age-associated penetrance in X-linked dystonia-parkinsonism

Trisha J. Multhaupt-Buell, I. König, P. Bauer, 2021, Nature Communications.

Empowering individual trait prediction using interactions for precision medicine

Damian Gola, Inke R. König, I. König, 2019, BMC Bioinformatics.

Modified entropy-based procedure detects gene-gene-interactions in unconventional genetic models

Jörg Malten, Inke R. König, I. König, 2020, BMC Medical Genomics.

Empowering individual trait prediction using interactions for precision medicine pdf

Damian Gola, Inke R. König, I. König, 2019, BMC Bioinformatics.

Probability estimation with machine learning methods for dichotomous and multicategory outcome: Applications

Christian Weimar, Andreas Ziegler, Yufeng Liu, 2014, Biometrical journal. Biometrische Zeitschrift.

Mining data with random forests: current options for real‐world applications

Andreas Ziegler, Inke R. König, I. König, 2014, WIREs Data Mining Knowl. Discov..

Validation in Genetic Association Studies

Inke R. König, I. König, 2011, Briefings Bioinform..

On safari to Random Jungle: a fast implementation of Random Forests for high-dimensional data

Andreas Ziegler, Daniel F. Schwarz, Inke R. König, 2010, Bioinform..

A Statistical Approach to Genetic Epidemiology: With Access to E-Learning Platform by Friedrich Pahlke

Andreas Ziegler, Inke R. König, I. König, 2010 .

ACPA: automated cluster plot analysis of genotype data

I. König, A. Ziegler, S. Szymczak, 2009, BMC proceedings.

Evaluation of single-nucleotide polymorphism imputation using random forests

Silke Szymczak, Andreas Ziegler, Inke R König, 2009, BMC proceedings.

Patient-centered yes/no prognosis using learning machines

I R König, J D Malley, S Pajevic, 2008, Int. J. Data Min. Bioinform..

Runs of Homozygosity: Association with Coronary Artery Disease and Gene Expression in Monocytes and Macrophages.

Mingyao Li, C. Loley, I. König, 2015, American journal of human genetics.

Effect of comorbid pulmonary disease on the severity of COVID‐19: A systematic review and meta‐analysis

I. König, U. Jappe, D. Drömann, 2021, Respirology.

Mendelian randomization: Progressing towards understanding causality

I. König, F. Greco, 2018, Annals of neurology.

Human genetic resistance to Onchocerca volvulus: evidence for linkage to chromosome 2p from an autosome-wide scan.

I. König, N. Brattig, M. Vens, 2008, The Journal of infectious diseases.

Metamizole and the risk of drug-induced agranulocytosis and neutropenia in statutory health insurance data

I. König, M. Schwaninger, R. Linder, 2019, Naunyn-Schmiedeberg's Archives of Pharmacology.

A Genome-Wide Association Study Reveals Variants in ARL15 that Influence Adiponectin Levels

Toshiko Tanaka, D. Melzer, T. Spector, 2009, PLoS genetics.

Design of the Coronary ARtery DIsease Genome-Wide Replication And Meta-Analysis (CARDIoGRAM) Study: A Genome-Wide Association Meta-analysis Involving More Than 22 000 Cases and 60 000 Controls

D. Absher, T. Assimes, K. Stefánsson, 2010, Circulation. Cardiovascular genetics.

Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease

He Zhang, Thomas Meitinger, Raimund Erbel, 2017, Journal of the American College of Cardiology.

Developmental Dyslexia – Recurrence Risk Estimates from a German Bi-Center Study Using the Single Proband Sib Pair Design

Bertram Müller-Myhsok, Andreas Ziegler, Andreas Warnke, 2005, Human Heredity.

Metastases-directed Radiotherapy in Addition to Standard Systemic Therapy in Patients with Oligometastatic Breast Cancer: Study protocol for a randomized controlled multi-national and multi-center clinical trial (OLIGOMA)

I. König, W. Klapper, J. Richter, 2021, Clinical and translational radiation oncology.

HLA‐DRB3*01:01 is a predictor of immunization against human platelet antigen‐1a but not of the severity of fetal and neonatal alloimmune thrombocytopenia

I. König, H. Hackstein, G. Bein, 2017, Transfusion.

Support Vector Machines for Survival Analysis with R

Claus Weihs, Marvin N. Wright, Inke R. König, 2018, R J..

Exploring Uncharted Territory: Genetically Determined Sex Differences in Parkinson's Disease

I. König, C. Klein, 2021, Annals of neurology.

Functional haplotypes of the RET proto-oncogene promoter are associated with Hirschsprung disease (HSCR).

Dietmar Roesner, Andreas Ziegler, Inke R König, 2003, Human molecular genetics.

A comprehensive evaluation of collapsing methods using simulated and real data: excellent annotation of functionality and large sample sizes required

Andreas Ziegler, Inke R. König, Mary V. Relling, 2014, Front. Genet..

Comparison of collapsing methods for the statistical analysis of rare variants

I. König, A. Ziegler, C. Hemmelmann, 2011, BMC proceedings.

Vitamin D and the Risk of Depression: A Causal Relationship? Findings from a Mendelian Randomization Study

I. König, J. Hebebrand, A. Hinney, 2019, Nutrients.

No association of vitamin D metabolism-related polymorphisms and melanoma risk as well as melanoma prognosis: a case–control study

C. Berking, I. König, J. Kruppa, 2012, Archives of Dermatological Research.

Genetic variants associated with cardiac structure and function: a meta-analysis and replication of genome-wide association data.

Thomas Meitinger, Uwe Völker, Reinhold Schmidt, 2009, JAMA.

Association Tests for X-Chromosomal Markers – A Comparison of Different Test Statistics

Andreas Ziegler, Christina Loley, Inke R. König, 2011, Human Heredity.

Current Developments of Clinical Sequencing and the Clinical Utility of Polygenic Risk Scores in Inflammatory Diseases

I. König, J. Erdmann, A. Franke, 2021, Frontiers in Immunology.

Polygenic risk scores outperform machine learning methods in predicting coronary artery disease status

Bertram Müller-Myhsok, Heribert Schunkert, Damian Gola, 2020, Genetic epidemiology.

A hexanucleotide repeat modifies expressivity of X‐linked dystonia parkinsonism

I. König, P. Bauer, N. Brüggemann, 2019, Annals of neurology.

Large‐scale determination of SNP allele frequencies in DNA pools using MALDI‐TOF mass spectrometry

Matthias Wjst, Thomas Illig, I. König, 2002, Human mutation.

What Do We Mean by ‘Replication’ and ‘Validation’ in Genome-Wide Association Studies?

Andreas Ziegler, Inke R. König, I. König, 2008, Human Heredity.

Microbiota-based analysis reveals specific bacterial traits and a novel strategy for the diagnosis of infectious infertility

I. König, J. Baines, J. Rupp, 2018, PloS one.

Variations of the melanocortin-1 receptor and the glutathione-S transferase T1 and M1 genes in cutaneous malignant melanoma

C. Berking, I. König, A. Ziegler, 2006, Archives of Dermatological Research.

Impact of imposed social isolation and use of face masks on asthma course and mental health in pediatric and adult patients with recurrent wheeze and asthma

Adan Chari Jirmo, I. König, D. DeLuca, 2021, Allergy, Asthma & Clinical Immunology.

Cytokine levels in children and adults with wheezing and asthma show specific patterns of variability over time

I. König, K. Rabe, G. Hansen, 2020, Clinical and experimental immunology.

Polymorphisms in the Renin-Angiotensin System and Outcome of Very-Low-Birthweight Infants

I. König, W. Göpel, H. Segerer, 2009, Neonatology.

Robotic stereotactic body radiotherapy for localized prostate cancer: final analysis of the German HYPOSTAT trial.

I. König, A. Muacevic, C. Rödel, 2023, Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al].

Extended Single Nucleotide Polymorphism and Haplotype Analysis of the elastin Gene in Caucasians with Intracranial Aneurysms Provides Evidence for Racially/Ethnically Based Differences

I. König, A. Ziegler, G. Schackert, 2004, Cerebrovascular Diseases.

Do little interactions get lost in dark random forests?

Andreas Ziegler, Marvin N. Wright, Inke R. König, 2016, BMC Bioinformatics.

Male-specific association between MT-ND4 11719 A/G polymorphism and ulcerative colitis: a mitochondria-wide genetic association study

I. König, A. Franke, D. Ellinghaus, 2016, BMC Gastroenterology.

Validity and Prognostic Value of a Polygenic Risk Score for Parkinson’s Disease

Ulrike M. Krämer, I. König, W. Lieb, 2021, Genes.

Evidence for linkage of restless legs syndrome to chromosome 9p

I. König, A. Ziegler, U. Stephani, 2008, Neurology.

Alcohol dehydrogenase 1C*1 allele is a genetic marker for alcohol‐associated cancer in heavy drinkers

I. König, K. Junghanns, D. Schuppan, 2006, International journal of cancer.

Optimized group sequential study designs for tests of genetic linkage and association in complex diseases.

A Ziegler, I R König, I. König, 2001, American journal of human genetics.

Strong genetic evidence of DCDC2 as a susceptibility gene for dyslexia.

Andreas Ziegler, Andreas Warnke, Sven Cichon, 2006, American journal of human genetics.

Rheumatoid Arthritis and Coronary Artery Disease: Genetic Analyses Do Not Support a Causal Relation

C. Loley, I. König, N. Samani, 2017, The Journal of Rheumatology.

Mosaic divergent repeat interruptions in XDP influence repeat stability and disease onset

I. König, N. Brüggemann, C. Depienne, 2022, Brain : a journal of neurology.

Principals about principal components in statistical genetics

Kristel Van Steen, Fentaw Abegaz, Jestinah M. Mahachie John, 2018, Briefings Bioinform..

Ceramide accumulation induces mitophagy and impairs β-oxidation in PINK1 deficiency

I. König, M. Vos, T. Lohnau, 2021, Proceedings of the National Academy of Sciences.

[German-language questionnaires for the standardized assessment of fecal incontinence and quality of life].

I. König, A. Ziegler, T. Schwandner, 2009, Deutsche medizinische Wochenschrift.

Triple Target Treatment (3T) Is More Effective Than Biofeedback Alone for Anal Incontinence: The 3T-AI Study

I. König, A. Ziegler, R. Bouchard, 2010, Diseases of the colon and rectum.

[3T-AI: a new treatment algorithm for anal incontinence with a higher evidence level].

I. König, W. Padberg, R. Bouchard, 2012, Zentralblatt fur Chirurgie.

Co-occurrence of affective and schizophrenia spectrum disorders with PINK1 mutations

I. König, R. Lencer, C. Klein, 2006, Journal of Neurology, Neurosurgery & Psychiatry.

Assessment of 3 xeroderma pigmentosum group C gene polymorphisms and risk of cutaneous melanoma: a case-control study.

Sikandar G. Khan, C. Berking, I. König, 2005, Carcinogenesis.

No association between three xeroderma pigmentosum group C and one group G gene polymorphisms and risk of cutaneous melanoma

Sikandar G. Khan, I. König, A. Ziegler, 2005, European Journal of Human Genetics.

Mendelian Randomization versus Path Models: Making Causal Inferences in Genetic Epidemiology

I. König, A. Ziegler, H. Mwambi, 2015, Human Heredity.

Angiography after Out-of-Hospital Cardiac Arrest without ST-Segment Elevation.

I. König, H. Thiele, M. Joner, 2021, The New England journal of medicine.

Linkage analyses of chromosomal region 18p11-q12 in dyslexia

M. Nöthen, I. König, A. Ziegler, 2006, Journal of Neural Transmission.

Challenges in disentangling the genetic background of Parkinson's disease

I. König, 2019, The Lancet Neurology.

DNA Methylation as a Potential Molecular Mechanism in X‐linked Dystonia‐Parkinsonism

I. König, C. Klein, R. Rosales, 2020, Movement disorders : official journal of the Movement Disorder Society.

Fluorescence Lifetime Imaging Unravels C. trachomatis Metabolism and Its Crosstalk with the Host Cell

Gereon Hüttmann, Inke R. König, Werner Solbach, 2011, PLoS pathogens.

Risk for antipsychotic-induced extrapyramidal symptoms: influence of family history and genetic susceptibility

I. König, R. Lencer, N. Brüggemann, 2011, Psychopharmacology.

C-Reactive Protein Stimulates Nicotinic Acetylcholine Receptors to Control ATP-Mediated Monocytic Inflammasome Activation

I. König, W. Padberg, W. Kummer, 2018, Front. Immunol..

Tissue Inhibitor of Metalloproteinases-1, −2, and −3 Polymorphisms in a White Population With Intracranial Aneurysms

I. König, A. Ziegler, G. Schackert, 2003, Stroke.

The all age asthma cohort (ALLIANCE) - from early beginnings to chronic disease: a longitudinal cohort study

I. König, H. Watz, K. Rabe, 2018, BMC Pulmonary Medicine.

Sleep apnoea in patients after treatment of head neck cancer

I. König, H. Graefe, B. Wollenberg, 2009, Acta oto-laryngologica.

Association of polymorphisms in the human surfactant protein‐D (SFTPD) gene and postnatal pulmonary adaptation in the preterm infant

I. König, A. Ziegler, L. Gortner, 2009, Acta paediatrica.

Patient selection for upper airway stimulation: is concentric collapse in sleep endoscopy predictable?

I. König, H. Frenzel, B. Wollenberg, 2015, Sleep and Breathing.

Immediate unselected coronary angiography versus delayed triage in survivors of out‐of‐hospital cardiac arrest without ST‐segment elevation: Design and rationale of the TOMAHAWK trial

I. König, H. Thiele, S. Fichtlscherer, 2019, American heart journal.

Tongue motion variability with changes of upper airway stimulation electrode configuration and effects on treatment outcomes

I. König, B. Hofauer, A. Steffen, 2018, The Laryngoscope.

Towards complete and accurate reporting of studies of diagnostic accuracy: the STARD initiative. Standards for Reporting of Diagnostic Accuracy.

I R König, D. Rennie, I. König, 2003, Clinical chemistry.

Genome-wide association study identifies a new locus for coronary artery disease on chromosome 10 p 11 . 23

C. Gieger, A. Peters, C. Loley, 2010 .

A Digital Health Application Allowing a Personalized Low-Glycemic Nutrition for the Prophylaxis of Migraine: Proof-of-Concept Data from a Retrospective Cohort Study

I. König, C. Gaul, C. Sina, 2022, Journal of clinical medicine.

Impulse Configuration in Hypoglossal Nerve Stimulation in Obstructive Sleep Apnea: The Effect of Modifying Pulse Width and Frequency.

I. König, R. Soose, A. Steffen, 2021, Neuromodulation : journal of the International Neuromodulation Society.

Home Sleep Testing to Direct Upper Airway Stimulation Therapy Optimization for Sleep Apnea

I. König, A. Steffen, P. Baptista, 2020, The Laryngoscope.

A novel biomarker-based prognostic score in acute ischemic stroke

A. Luft, I. König, G. D. De Marchis, 2019, Neurology.

Genetic variants associated with celiac disease and the risk for coronary artery disease

I. König, N. Samani, J. Erdmann, 2015, Molecular Genetics and Genomics.

GT-repeat extension in the IL11 promoter is associated with Hirschsprung's disease (HSCR).

I. König, M. Haase, S. Grover, 2018, Gene.

Preliminary report on elective preterm delivery at 34 weeks and primary abdominal closure for the management of gastroschisis.

I. König, A. Serra, G. Fitze, 2008, European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie.

Genetic variants primarily associated with type 2 diabetes are related to coronary artery disease risk.

C. Gieger, T. Assimes, A. Peters, 2015, Atherosclerosis.

Genetic background of high blood pressure is associated with reduced mortality in premature neonates

I. König, W. Göpel, A. Franke, 2019, Archives of Disease in Childhood: Fetal and Neonatal Edition.

Matrix Metalloproteinase-9 Coding Sequence Single-nucleotide Polymorphisms in Caucasians with Intracranial Aneurysms

I. König, A. Ziegler, G. Schackert, 2004, Neurosurgery.

THE D216H VARIANT IN THE DYT1 GENE: A SUSCEPTIBILITY FACTOR FOR DYSTONIA IN FAMILIAL CASES?

I. König, A. Ziegler, E. Altenmüller, 2009, Neurology.

Parkin Deficiency Appears Not to Be Associated with Cardiac Damage in Parkinson's Disease

I. König, N. Brüggemann, K. Lohmann, 2021, Movement disorders : official journal of the Movement Disorder Society.

Mean corpuscular volume and ADH1C genotype in white patients with alcohol-associated diseases.

I. König, K. Junghanns, H. Seitz, 2005, Alcoholism, clinical and experimental research.

Association of polymorphisms in the mannose-binding lectin gene and pulmonary morbidity in preterm infants

I. König, A. Ziegler, L. Gortner, 2007, Genes and Immunity.

RNA‐seq–based profiling of extracellular vesicles in plasma reveals a potential role of miR‐122‐5p in asthma

I. König, H. Watz, K. Rabe, 2020, Allergy.

Supine position and REM dependence in obstructive sleep apnea

I. König, A. Steffen, L. Maibücher, 2016, HNO.

Challenges in planning and conducting diagnostic studies with molecular biomarkers

I. König, P. Schulz-Knappe, A. Ziegler, 2013, Deutsche Medizinische Wochenschrift.

Effect of Electrode Configuration and Impulse Strength on Airway Patency in Neurostimulation for Obstructive Sleep Apnea

I. König, E. Thaler, A. Steffen, 2021, The Laryngoscope.

Evaluation of body position in upper airway stimulation for obstructive sleep apnea—is continuous voltage sufficient enough?

I. König, B. Hofauer, A. Steffen, 2018, Sleep and Breathing.

Association of a functional polymorphism in the CYP4A11 gene with systolic blood pressure in survivors of myocardial infarction

I. König, A. Ziegler, H. Hense, 2006, Journal of hypertension.

Genome-Wide Association Study of L-Arginine and Dimethylarginines Reveals Novel Metabolic Pathway for Symmetric Dimethylarginine

M. Fornage, K. Lunetta, C. Gieger, 2014, Circulation. Cardiovascular genetics.

Measurement of Midregional Pro-Atrial Natriuretic Peptide to Discover Atrial Fibrillation in Patients With Ischemic Stroke.

A. Luft, I. König, A. von Eckardstein, 2022, Journal of the American College of Cardiology.

p53 Mutations in Carcinoma of the Esophagus and Gastroesophageal Junction

I. König, D. Rades, M. Duchrow, 2009, Cancer investigation.

MDR1 variants and risk of Parkinson disease

I. König, A. Ziegler, N. Brüggemann, 2009, Journal of Neurology.

Genotype–Phenotype Relations for the Atypical Parkinsonism Genes:MDSGene Systematic Review

I. König, H. Huppertz, M. Stamelou, 2021, Movement disorders : official journal of the Movement Disorder Society.

[Evidence of positive care effects by digital health apps-methodological challenges and approaches].

I. König, M. Möckel, C. Sina, 2022, Innere Medizin.

Comments on ‘Mendelian randomization: using genes as instruments for making causal inferences in epidemiology’ by Debbie A. Lawlor, R. M. Harbord, J. A. Sterne, N. Timpson and G. Davey Smith, Statistics in Medicine, DOI: 10.1002/sim.3034

Andreas Ziegler, Inke R König, Friedrich Pahlke, 2008, Statistics in Medicine.

Effect of Chloride - Administration in the Therapy of Acute Pancreatitis - A Retrospective Analysis of 493 Cases

I. König, F. Bär, J. Büning, 2019 .

Candidate gene studies in focal dystonia

I. König, A. Ziegler, M. Vidailhet, 2003, Neurology.

Substantia nigra hyperechogenicity correlates with clinical status and number of Parkin mutated alleles

G. Seidel, B. Becker, I. König, 2007, Journal of Neurology.

Life-long increase of substantia nigra hyperechogenicity in transcranial sonography

Inke R. König, Johann Hagenah, Jürgen Sperner, 2010, NeuroImage.

Mendelian randomization analysis does not support causal associations of birth weight with hypertension risk and blood pressure in adulthood

A. Hofman, A. Peters, D. Mozaffarian, 2020, European Journal of Epidemiology.

An omics-based strategy using coenzyme Q10 in patients with Parkinson’s disease: concept evaluation in a double-blind randomized placebo-controlled parallel group trial

I. König, A. Ziegler, D. Berg, 2019, Neurological Research and Practice.

Mitochondrial DNA Deletions Discriminate Affected from Unaffected LRRK2 Mutation Carriers

I. König, M. Farrer, C. Klein, 2019, Annals of neurology.

Association of SNCA variants with α-synuclein of gastric and colonic mucosa in Parkinson's disease.

I. König, Seung‐Mo Hong, K. Lohmann, 2019, Parkinsonism & related disorders.

Genetic variation in the arachidonate 5-lipoxygenase-activating protein (ALOX5AP) is associated with myocardial infarction in the German population.

I. König, A. Ziegler, J. Erdmann, 2008, Clinical science.

Genome-Wide Linkage Analysis of Malaria Infection Intensity and Mild Disease

I. König, A. Ziegler, F. Rüschendorf, 2007, PLoS genetics.

Celebrating the 30th Anniversary of Genetic Epidemiology: How to Define Our Scope?†

I. König, A. Ziegler, 2014, Genetic epidemiology.

Lack of Association Between the MEF2A Gene and Myocardial Infarction

I. König, A. Ziegler, J. Erdmann, 2008, Circulation.

First approach to distinguish between cardiac and arteriosclerotic emboli of individual stroke patients applying the histological THROMBEX-classification rule

I. König, G. Royl, F. Roessler, 2021, Scientific Reports.

Lipobiotin-capture magnetic bead assay for isolation, enrichment and detection of Mycobacterium tuberculosis from saliva

I. König, N. Reiling, K. Wiesmüller, 2022, bioRxiv.

HLA‐DRB genotyping in Gilles de la Tourette patients and their parents

I. König, A. Ziegler, W. Oertel, 2003, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

Radiosurgery for ventricular tachycardia (RAVENTA): interim analysis of a multicenter multiplatform feasibility trial

I. König, D. Rades, A. Schweikard, 2023, Strahlentherapie und Onkologie.

Investigation of interaction between DCDC2 and KIAA0319 in a large German dyslexia sample

Bertram Müller-Myhsok, Andreas Ziegler, Andreas Warnke, 2008, Journal of Neural Transmission.

Genetic variation of TNF is associated with sepsis syndrome and death in severely injured patients

I. König, T. Chakraborty, T. Menges, 2006, Critical Care.

Head impulse testing in bilateral vestibulopathy in patients with genetically defined CANVAS

I. König, N. Brüggemann, K. Lohmann, 2022, Brain and Behavior.

Splitting on categorical predictors in random forests

Marvin N. Wright, Inke R König, Marvin N Wright, 2019, PeerJ.

Effects of a rater training on rating accuracy in a physical examination skills assessment

I. König, G. Weitz, Christoph Twesten, 2014, GMS Zeitschrift fur medizinische Ausbildung.

Basal ganglia hyperechogenicity does not distinguish between patients with primary dystonia and healthy individuals

I. König, N. Brüggemann, C. Klein, 2011, Journal of Neurology.

Population Bias in Polygenic Risk Prediction Models for Coronary Artery Disease

R. Mägi, I. König, J. Erdmann, 2020, Circulation. Genomic and precision medicine.

Glyoxal in hyperglycaemic ischemic stroke – a cohort study

I. König, M. Schwaninger, P. Nawroth, 2023, Cardiovascular Diabetology.

Retrospective analysis of the long-term therapeutic effectiveness and safety profile of rituximab in the treatment of mucous membrane pemphigoid in a German university center between 2008 and 2019

I. König, D. Zillikens, D. Gola, 2023, Frontiers in Immunology.

Genetic Evidence for PLASMINOGEN as a Shared Genetic Risk Factor of Coronary Artery Disease and Periodontitis

C. Gieger, M. Waldenberger, A. Peters, 2015, Circulation. Cardiovascular genetics.

Association of TNF -238 and -308 promoter polymorphisms with psoriasis vulgaris and psoriatic arthritis but not with pustulosis palmoplantaris.

I. König, K. Reich, K. Kingo, 2005, The Journal of investigative dermatology.

Very low birth weight infants after discharge: What do parents describe?

I. König, W. Göpel, N. Teig, 2013, Early human development.

Contents Vol. 16, 2003

Cheryl C. H. Yang, A. Rahimi, I. König, 2003, Cerebrovascular Diseases.

COL4A3 is degraded in allergic asthma and degradation predicts response to anti-IgE therapy

I. König, M. Karsdal, K. Rabe, 2021, European Respiratory Journal.

Sonothrombolysis in acute ischemic stroke for patients ineligible for rt-PA

Inke R König, Björn Koch, I. König, 2005, Neurology.

Further evidence for a susceptibility locus contributing to reading disability on chromosome 15q15–q21

M. Nöthen, I. König, A. Ziegler, 2008, Psychiatric genetics.

Transferring entropy to the realm of GxG interactions

Paola G. Ferrario, Inke R. König, I. König, 2016, Briefings Bioinform..

Variations in the peroxisome proliferator-activated receptor-gamma gene and melanoma risk.

C. Berking, I. König, A. Ziegler, 2007, Cancer letters.

Correction to: The all age asthma cohort (ALLIANCE) - from early beginnings to chronic disease: a longitudinal cohort study

I. König, H. Watz, K. Rabe, 2018, BMC Pulmonary Medicine.

Molecular Signatures of Cardiovascular Disease Risk

I. König, J. Erdmann, H. Schunkert, 2012, Molecular Diagnosis & Therapy.

University of Dundee Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease

Andrew D. Johnson, John D. Eicher, K. Stirrups, 2022 .

Botulinum toxin for Frey's syndrome: a closer look at different treatment responses.

I. König, B. Wollenberg, N. Rotter, 2012, The Journal of laryngology and otology.

[Analysis of psychosocial changes following ear reconstruction with rib cartilage - development of a short test].

I. König, H. Frenzel, A. Steffen, 2009, Laryngo- rhino- otologie.

Age and National Institutes of Health Stroke Scale Score Within 6 Hours After Onset Are Accurate Predictors of Outcome After Cerebral Ischemia: Development and External Validation of Prognostic Models

A. Ziegler, C. Weimar, I. König, 2003, Stroke.

Do little interactions get lost in dark random forests?

Marvin N. Wright, I. König, Andreas Ziegler, 2016, BMC Bioinformatics.

Interrelationship and Familiality of Dyslexia Related Quantitative Measures

A Ziegler, I R König, H Remschmidt, 2007, Annals of human genetics.

A comprehensive 1000 Genomes-based genome-wide association meta-analysis of coronary artery disease

Sebastian M. Armasu, J. Danesh, R. Collins, 2015, Nature Genetics.

Is there a male-specific effect on hypertension?

I. König, A. Ziegler, W. Lieb, 2015, Human Genetics.

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

Thomas W. Mühleisen, David M. Evans, M. Jarvelin, 2013, Nature Genetics.

Association analyses of 249,796 individuals reveal eighteen new loci associated with body mass index

Henrik, Tanya M. Teslovich, Jennie, 2012 .

Genetic Analysis Workshop 19: methods and strategies for analyzing human sequence and gene expression data in extended families and unrelated individuals

Ellen M. Wijsman, Justo Lorenzo Bermejo, Laura Almasy, 2016, BMC Proceedings.

Look who is calling: a comparison of genotype calling algorithms

I. König, A. Ziegler, A. Schillert, 2009, BMC proceedings.

Repeated Replication and a Prospective Meta-Analysis of the Association Between Chromosome 9p21.3 and Coronary Artery Disease

P. Deloukas, I. König, L. Hothorn, 2008, Circulation.

Extracorporeal Shock Wave Therapy in the Treatment of Lateral Epicondylitis: A Randomized Multicenter Trial

M. Loew, I. König, A. Betthäuser, 2002, The Journal of bone and joint surgery. American volume.

Large-scale association analysis identifies new risk loci for coronary artery disease

J. Danesh, R. Collins, D. Absher, 2012, Nature Genetics.

Genome-wide association study and targeted metabolomics identifies sex-specific association of CPS1 with coronary artery disease

D. Absher, T. Assimes, P. Deloukas, 2016, Nature Communications.

Multiple testing in high‐throughput sequence data: experiences from Group 8 of Genetic Analysis Workshop 17

I. König, M. A. Simonson, J. Nsengimana, 2011, Genetic epidemiology.

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

Thomas W. Mühleisen, M. Jarvelin, M. Peters, 2013, Nature Genetics.

Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function

Tom R. Gaunt, Nicholette D. Palmer, Y. J. Kim, 2016, Nature Communications.

Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease.

Rajiv, Martina, Raimund, 2016, The New England journal of medicine.

Evaluating the current state of Mendelian randomization studies: a protocol for a systematic review on methodological and clinical aspects using neurodegenerative disorders as outcome

I. König, F. Del Greco M, S. Grover, 2018, Systematic Reviews.

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

Thomas W. Mühleisen, M. Jarvelin, M. Peters, 2013, Nature Genetics.

Reply to: “In Support of Electronic Versions of Movement Disorder Society Rating Scales”

I. König, N. Brüggemann, K. Lohmann, 2021 .

Parkin Deficiency Appears Not to Be Associated with Cardiac Damage in Parkinson's Disease

I. König, N. Brüggemann, K. Lohmann, 2021, Movement disorders : official journal of the Movement Disorder Society.

Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants

Joshua M. Korn, Benjamin J. Wright, P. Deloukas, 2009, Nature Genetics.

What is precision medicine?

I. König, G. Hansen, E. von Mutius, 2017, European Respiratory Journal.

Association analyses of 249,796 individuals reveal eighteen new loci associated with body mass index

Tanya M. Teslovich, M. Jarvelin, L. Coin, 2010, Nature genetics.

Association analyses of 249 , 796 individuals reveal 18 new loci associated with body mass index

Tanya M. Teslovich, Eric, P. Elliott, 2012 .

Genetic variants associated with celiac disease and the risk for coronary artery disease

I. König, N. Samani, J. Erdmann, 2015, Molecular Genetics and Genomics.

Expanded nursing competencies to improve person-centred care for nursing home residents with complex health needs (Expand-Care): study protocol for an exploratory cluster-randomised trial

I. König, K. Balzer, D. Lühmann, 2023, BMJ Open.

Predicting Long-Term Outcome After Acute Ischemic Stroke: A Simple Index Works in Patients From Controlled Clinical Trials

I. König, A. Ziegler, R. Sacco, 2008, Stroke.

Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function

Tom R. Gaunt, Nicholette D. Palmer, Y. J. Kim, 2016, Nature Communications.

Practical experiences on the necessity of external validation

Michael Green, Ulf Ekelund, Jonas Björk, 2007, Statistics in medicine.

Sonothrombolysis With Transcranial Color-Coded Sonography and Recombinant Tissue-Type Plasminogen Activator in Acute Middle Cerebral Artery Main Stem Occlusion: Results From a Randomized Study

I. König, G. Seidel, J. Eggers, 2008, Stroke.

Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease.

Dermot F. Reilly, J. Danesh, M. Waldenberger, 2016, New England Journal of Medicine.

Coding variation in ANGPTL4, LPL, and SVEP1 and the risk of coronary disease

K. Stirrups, I. König, N. Stitziel, 2016 .

What is precision medicine?

I. König, M. Nakanishi, Oliver Fuchs, 2017, European Respiratory Journal.

Risk estimation and risk prediction using machine-learning methods

Andreas Ziegler, Jochen Kruppa, Inke R. König, 2012, Human Genetics.