S. Gough

S. Gough, H. Rodbard, Y. Handelsman, 2014, Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists.

Genome-Wide Association Analysis of Autoantibody Positivity in Type 1 Diabetes Cases

John A. Todd, Chris Wallace, Vincent Plagnol, 2011, PLoS genetics.

S. Gough, L. Heinemann, J. deVries, 2014, Diabetes, obesity & metabolism.

Negligible impact of rare autoimmune-locus coding-region variants on missing heritability

D. MacArthur, J. Todd, J. Barrett, 2013, Nature.

Post-marketing surveillance: a UK/European perspective

S. Gough, Stephen Gough, 2005, Current medical research and opinion.

Influences of age, gender, smoking, and family history on autoimmune thyroid disease phenotype.

J. Franklyn, S. Gough, J. Carr-Smith, 2006, The Journal of clinical endocrinology and metabolism.

Prevalence and relative risk of other autoimmune diseases in subjects with autoimmune thyroid disease.

Roger Holder, John H. Lazarus, Simon H. S. Pearce, 2010, The American journal of medicine.

Comparative performances of machine learning methods for classifying Crohn Disease patients using genome-wide genotyping data

Judy H. Cho, John P. Ferguson, G. Wainrib, 2019, Scientific Reports.

FCGR3B copy number variation is associated with susceptibility to systemic, but not organ-specific, autoimmunity

Philippe Froguel, Enrico Petretto, Alexandra I. F. Blakemore, 2007, Nature Genetics.

Immunogenetic Mechanisms Leading to Thyroid Autoimmunity: Recent Advances in Identifying Susceptibility Genes and Regions

S. Gough, O. Brand, 2011, Current genomics.

Copy number variation in common disease.

S. Gough, O. Brand, 2011, Thyroid : official journal of the American Thyroid Association.

Genetic developments in autoimmune thyroid disease: an evolutionary process

M. Simmonds, S. Gough, A. Zeitlin, 2008, Clinical endocrinology.

A genome-wide screen in 1119 relative pairs with autoimmune thyroid disease.

J. Connell, J. Franklyn, S. Gough, 2006, The Journal of clinical endocrinology and metabolism.

CTLA4 gene polymorphism and autoimmunity

S. Gough, L. Walker, D. Sansom, 2005, Immunological reviews.

Evidence for a Type 1 diabetes‐specific mechanism for the insulin gene‐associated IDDM2 locus rather than a general influence on autoimmunity

J. Heward, S. Gough, S. Sawcer, 2004, Diabetic medicine : a journal of the British Diabetic Association.

The deleted in colorectal carcinoma (DCC) gene 201 R → G polymorphism: no evidence for genetic association with autoimmune disease

J. Heward, S. Gough, T. Merriman, 2003, European Journal of Human Genetics.

The genetics of autoimmune endocrine disease

S. Gough, K. Tait, 2003, Clinical endocrinology.

Sharing of susceptibility loci between autoimmune diseases: lack of association of the insulin gene region with Graves' disease.

J. Franklyn, S. Gough, J. Carr-Smith, 1999, Thyroid : official journal of the American Thyroid Association.

Identification of Trinucleotide Repeat–Containing Genes in Human Pancreatic Islets

S. Gough, P. Froguel, M. Vaxillaire, 1996, Diabetes.

Susceptibility to human type 1 diabetes at IDDM2 is determined by tandem repeat variation at the insulin gene minisatellite locus

J. Todd, S. Gough, A. Cambon-Thomsen, 1995, Nature Genetics.

Chromosome–specific microsatellite sets for fluorescence–based, semi–automated genome mapping

S. C. Jenkins, J. Todd, S. Gough, 1994, Nature Genetics.

The different approaches to the genetic analysis of autoimmune thyroid disease.

S. Gough, A. Allahabadia, 1999, The Journal of endocrinology.

Think cytokines before you drink

S. Gough, 2000, Gut.

The immunogenetics of Graves' disease

S. Gough, 1999 .

Linkage disequilibrium between the human leukocyte antigen class II region of the major histocompatibility complex and Graves' disease: replication using a population case control and family-based study.

J. Franklyn, J. Heward, S. Gough, 1998, The Journal of clinical endocrinology and metabolism.

Immunogenetic Factors in Autoimmunity

J. Heward, S. Gough, 2007 .

HLA, CTLA-4 and PTPN22: the shared genetic master-key to autoimmunity?

J. Heward, S. Gough, O. Brand, 2005, Expert Reviews in Molecular Medicine.

Polymorphisms of Interleukin 4 Receptor Gene and Interleukin 10 Gene are not Associated with Graves' Disease in the UK

J. Franklyn, J. Heward, S. Gough, 2004, Autoimmunity.

Parameters for reliable results in genetic association studies in common disease

John A. Todd, Francesco Cucca, Heather J. Cordell, 2002, Nature Genetics.

A systematic approach to the assessment of known TNF-α polymorphisms in Graves' disease

J. Franklyn, M. Simmonds, S. Gough, 2004, Genes and Immunity.

Mutation of the glucagon receptor gene and diabetes mellitus in the UK: association or founder effect?

S. Gough, T. Merriman, R. Turner, 1995, Human molecular genetics.

The development of Graves' disease and the CTLA-4 gene on chromosome 2q33.

J. Franklyn, J. Heward, S. Gough, 1999, The Journal of clinical endocrinology and metabolism.

Association of the TSHR gene with Graves' disease: the first disease specific locus

J. Connell, J. Franklyn, S. Gough, 2005, European Journal of Human Genetics.

Analysis of HLA class II genes in Hashimoto's thyroiditis reveals differences compared to Graves’ disease

J. Franklyn, M. Simmonds, S. Gough, 2008, Genes and Immunity.

Association of PTPN22 haplotypes with Graves' disease.

J. Barrett, J. Franklyn, J. Heward, 2007, The Journal of clinical endocrinology and metabolism.

Low molecular weight heparin.

S. Gough, 1991, BMJ.

Association of a rare thyroglobulin gene microsatellite variant with autoimmune thyroid disease.

J. Franklyn, J. Heward, S. Gough, 2003, The Journal of clinical endocrinology and metabolism.

Thyroid Stimulating Hormone Receptor (TSHR) Intron 1 Variants Are Major Risk Factors for Graves' Disease in Three European Caucasian Cohorts

J. Franklyn, M. Simmonds, S. Gough, 2010, PloS one.

Association of the interleukin‐2 receptor alpha (IL‐2Rα)/CD25 gene region with Graves’ disease using a multilocus test and tag SNPs

J. Todd, J. Franklyn, J. Heward, 2007, Clinical endocrinology.

Clustering of metabolic comorbidity in schizophrenia: a genetic contribution?

M. O’Donovan, S. Gough, 2005, Journal of psychopharmacology.

CD226 Gly307Ser association with multiple autoimmune diseases

J. Todd, H. Stevens, N. Walker, 2009, Genes and Immunity.

Genetic insights into disease mechanisms of autoimmunity.

M. Simmonds, S. Gough, 2004, British medical bulletin.

Safety and Efficacy of Sitagliptin-Metformin in Fixed Combination for the Treatment of Type 2 Diabetes Mellitus

S. Gough, C. Ballav, 2013, Clinical medicine insights. Endocrinology and diabetes.

The search for the genetic contribution to autoimmune thyroid disease: the never ending story?

M. Simmonds, S. Gough, 2011, Briefings in functional genomics.

Fibrinolytic activity in rheumatoid arthritis and the effects of prednisolone therapy

S. Gough, T. Pullar, P. Grant, 1993 .

Elderly Patients with Diabetes Experience a Lower Rate of Nocturnal Hypoglycaemia with Insulin Degludec than with Insulin Glargine: A Meta-Analysis of Phase IIIa Trials

S. Gough, D. Oyer, M. Warren, 2013, Drugs & Aging.

Seven newly identified loci for autoimmune thyroid disease

J. Todd, H. Stevens, N. Walker, 2012, Human molecular genetics.

Management of peripheral arterial disease in primary care

S. Gough, A. Bradbury, P. Burns, 2003, BMJ : British Medical Journal.

A heterozygous deletion of the autoimmune regulator (AIRE1) gene, autoimmune thyroid disease, and type 1 diabetes: no evidence for association.

J. Franklyn, S. Gough, A. Barnett, 2000, The Journal of clinical endocrinology and metabolism.

Cytotoxic T-lymphocyte associated antigen 4 gene polymorphisms and autoimmune thyroid disease: a meta-analysis.

J. Ioannidis, J. Heward, S. Gough, 2007, The Journal of clinical endocrinology and metabolism.

A novel and major association of HLA-C in Graves' disease that eclipses the classical HLA-DRB1 effect.

J. Todd, J. Franklyn, J. Heward, 2007, Human molecular genetics.

Autoimmunity in thyroid disease

S. Gough, J. Collins, 2002, European Journal of Nuclear Medicine and Molecular Imaging.

Regression mapping of association between the human leukocyte antigen region and Graves disease.

J. Todd, N. Walker, J. Franklyn, 2005, American journal of human genetics.

Impact of month of birth on the development of autoimmune thyroid disease in the United Kingdom and Europe.

J. Connell, J. Franklyn, M. Simmonds, 2014, The Journal of clinical endocrinology and metabolism.

Lack of association of the vitamin D receptor gene with Graves’ disease in UK Caucasians

J. Todd, J. Franklyn, J. Heward, 2004, Clinical endocrinology.

Liraglutide: from clinical trials to clinical practice

S. Gough, 2012, Diabetes, obesity & metabolism.

Insulin degludec: overview of a novel ultra long‐acting basal insulin

S. Gough, V. Woo, V. Woo, 2013, Diabetes, obesity & metabolism.

Association of the thyroid stimulating hormone receptor gene (TSHR) with Graves' disease.

J. Barrett, J. Connell, J. Franklyn, 2009, Human molecular genetics.

Recent advances with insulin degludec for the treatment of Type 2 diabetes

S. Gough, V. Stokes, 2014, Expert review of endocrinology & metabolism.

Hypoglycaemia risk with insulin degludec compared with insulin glargine in type 2 and type 1 diabetes: a pre-planned meta-analysis of phase 3 trials

S. Gough, B. Zinman, C. Mathieu, 2012, Diabetes, obesity & metabolism.

Association of caveolin-1 gene polymorphism with kidney transplant fibrosis and allograft failure.

M. Simmonds, S. Gough, O. Brand, 2010, JAMA.

Liraglutide efficacy and action in non-alcoholic steatohepatitis (LEAN): study protocol for a phase II multicentre, double-blinded, randomised, controlled trial

Rachel M. Brown, S. Gough, D. Stocken, 2013, BMJ Open.

Contribution of single nucleotide polymorphisms within FCRL3 and MAP3K7IP2 to the pathogenesis of Graves' disease.

J. Franklyn, J. Heward, M. Simmonds, 2006, The Journal of clinical endocrinology and metabolism.

Radioiodine treatment of hyperthyroidism-prognostic factors for outcome.

J. Franklyn, S. Gough, A. Allahabadia, 2001, The Journal of clinical endocrinology and metabolism.

The A-G polymorphism in exon 1 of theCTLA-4 gene is not associated with systemic lupus erythematosus

J. Franklyn, J. Heward, S. Gough, 1999, Annals of the rheumatic diseases.

Matrix metalloprotease polymorphisms are associated with gas transfer in alpha 1 antitrypsin deficiency

S. Gough, R. Stockley, C. McAloon, 2009, Therapeutic advances in respiratory disease.

'Loss of self': a psychosocial study of the quality of life of adults with diabetic foot ulceration.

S. Gough, R. Ashford, K. Kinmond, 2002, Journal of tissue viability.

Diabetes and its prevention: Pragmatic solutions for people with schizophrenia

S. Gough, R. Peveler, 2004, British Journal of Psychiatry.

Association of FcGRIIa with Graves’ disease: a potential role for dysregulated autoantibody clearance in disease onset/progression

J. Franklyn, J. Heward, M. Simmonds, 2010, Clinical endocrinology.

Confirmation of association of chromosome 5q31-33 with United Kingdom Caucasian Graves' disease.

J. Franklyn, M. Simmonds, S. Gough, 2010, Thyroid : official journal of the American Thyroid Association.

Donor ABCB1 variant associates with increased risk for kidney allograft failure.

M. Simmonds, S. Gough, O. Brand, 2012, Journal of the American Society of Nephrology : JASN.

The TNFalpha gene relates to clinical phenotype in alpha-1-antitrypsin deficiency

M. Simmonds, S. Gough, R. Stockley, 2008, Respiratory research.

Phenotypic Differences in Alpha 1 Antitrypsin-Deficient Sibling Pairs May Relate to Genetic Variation

M. Simmonds, S. Gough, R. Stockley, 2008, COPD.

Comparison of IFCC-calibrated HbA(1c) from laboratory and point of care testing systems.

S. Gough, I. Stratton, S. Manley, 2014, Diabetes research and clinical practice.

A look into the future: improving diabetes care by 2015

S. Gough, M. Peyrot, D. Schneider, 2011, Current medical research and opinion.

Acute spontaneous compartment syndrome in recent onset type 1 diabetes

S. Gough, H. Mahdi, B. Mahon, 2007, Emergency Medicine Journal.

One‐year efficacy and safety of a fixed combination of insulin degludec and liraglutide in patients with type 2 diabetes: results of a 26‐week extension to a 26‐week main trial

S. Gough, H. Rodbard, B. Bode, 2015, Diabetes, obesity & metabolism.

Efficacy and safety of a fixed-ratio combination of insulin degludec and liraglutide (IDegLira) compared with its components given alone: results of a phase 3, open-label, randomised, 26-week, treat-to-target trial in insulin-naive patients with type 2 diabetes.

S. Gough, P. Poulsen, H. Rodbard, 2014, The Lancet Diabetes and Endocrinology.

Safety and efficacy of liraglutide in patients with type 2 diabetes and elevated liver enzymes: individual patient data meta‐analysis of the LEAD program

S. Gough, M. Armstrong, D. Houlihan, 2013, Alimentary pharmacology & therapeutics.

Low-Volume Insulin Degludec 200 Units/mL Once Daily Improves Glycemic Control Similarly to Insulin Glargine With a Low Risk of Hypoglycemia in Insulin-Naïve Patients With Type 2 Diabetes

S. Gough, R. Bergenstal, A. Bhargava, 2013, Diabetes Care.

The Efficacy and Safety of Insulin Degludec Given in Variable Once-Daily Dosing Intervals Compared With Insulin Glargine and Insulin Degludec Dosed at the Same Time Daily

S. Gough, K. Begtrup, L. Blonde, 2013, Diabetes Care.

Current and future therapies for type 1 diabetes

S. Gough, M. V. von Herrath, B. V. von Scholten, 2021, Diabetologia.

Benefits of combination of insulin degludec and liraglutide are independent of baseline glycated haemoglobin level and duration of type 2 diabetes

S. Gough, H. Rodbard, J. Buse, 2015, Diabetes, obesity & metabolism.

Severe hypoglycaemia in adults with insulin‐treated diabetes: impact on healthcare resources

S. Gough, S. Heller, B. Frier, 2015, Diabetic medicine : a journal of the British Diabetic Association.

Liraglutide More Effectively Achieves a Composite Endpoint for A1C, SBP and Weight Change Than Other Diabetes Therapies

S. Gough, B. Zinman, J. Buse, 2009 .

Rare and functional SIAE variants are not associated with autoimmune disease risk in up to 66,924 individuals of European ancestry

Tariq Ahmad, Sarah Edkins, Christopher G Mathew, 2011, Nature Genetics.

Pancreas transplantation: a treatment option for people with diabetes

S. Gough, S. Mittal, 2014, Diabetic medicine : a journal of the British Diabetic Association.

Genetic Variation in Caveolin‐1 Correlates With Long‐Term Pancreas Transplant Function

M. Simmonds, S. Gough, S. Fuggle, 2015, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

Impact of obesity and type 2 diabetes on health-related quality of life in the general population in England

S. Gough, N. Kragh, M. Hammer, 2009, Diabetes, metabolic syndrome and obesity : targets and therapy.

Early change in blood glucose concentration is an indicator of mortality in critically ill children

S. Gough, J. Stickley, P. Narendran, 2012, Intensive Care Medicine.

Bydureon: long‐acting exenatide for once‐weekly injection

S. Gough, C. Ballav, 2012 .

CT60 and +49 polymorphisms of CTLA 4 are associated with ANCA-positive small vessel vasculitis.

J. Heward, S. Gough, A. Salama, 2009, Rheumatology.

Recent advances in incretin‐based therapies

S. Gough, D. Russell-Jones, 2012, Clinical endocrinology.

Insulin degludec does not compromise efficacy or safety when given in a flexible once-daily dosing regimen compared to insulin glargine once daily at the same time each day in type 2 diabetes

S. Gough, K. Begtrup, L. Blonde, 2011 .