M. Stratton

Rebecca A Betensky, Tracy T Batchelor, Patrick J Codd, 2007, Clinical cancer research : an official journal of the American Association for Cancer Research.

Mapping the temporal and spatial dynamics of the human endometrium in vivo and in vitro

Lia S. Campos, Ben J. Woodhams, S. Teichmann, 2021, Nature Genetics.

The Human Cell Atlas

Roland Eils, Alexander van Oudenaarden, Hans Clevers, 2017, bioRxiv.

The circular RNome of primary breast cancer

Alain Viari, Johan Staaf, Carlos Caldas, 2019, Genome research.

Detection of allelic imbalance indicates that a proportion of mammary hyperplasia of usual type are clonal, neoplastic proliferations.

M. Stratton, S. Lakhani, J. Sloane, 1996, Laboratory investigation; a journal of technical methods and pathology.

Atypical ductal hyperplasia of the breast: clonal proliferation with loss of heterozygosity on chromosomes 16q and 17p.

M. Stratton, S. Lakhani, J. Sloane, 1995, Journal of clinical pathology.

Pan-cancer analysis of homozygous deletions in primary tumours uncovers rare tumour suppressors

Yves Moreau, Kevin P. White, Peter J. Campbell, 2017, Nature Communications.

A survey of RNA editing in human brain.

Richard Wooster, Matthew Blow, Michael R Stratton, 2004, Genome research.

Loss of heterozygosity in ductal carcinoma in situ of the breast

M. Stratton, S. Lakhani, J. Sloane, 1995, The Journal of pathology.

Variants in CHEK2 other than 1100delC do not make a major contribution to breast cancer susceptibility.

Nazneen Rahman, Carel Meijers, Sheila Seal, 2003, American journal of human genetics.

Genome Sequencing and Analysis of the Tasmanian Devil and Its Transmissible Cancer

Carolyn Tregidgo, Albert J. Vilella, Peter J. Campbell, 2012, Cell.

Elevated somatic mutation burdens in normal human cells due to defective DNA polymerases

M. Stratton, P. Campbell, I. Martincorena, 2020, bioRxiv.

Evaluation of RAD50 in familial breast cancer predisposition

Päivi Heikkilä, Jiri Bartek, Nazneen Rahman, 2006, International journal of cancer.

Haplotype and phenotype analysis of six recurrent BRCA1 mutations in 61 families: results of an international study.

M. King, M. Skolnick, D. Easton, 1996, American journal of human genetics.

Mutation allele burden remains unchanged in chronic myelomonocytic leukaemia responding to hypomethylating agents

M. Stratton, F. Artiguenave, L. Alexandrov, 2016, Nature Communications.

Clinical significance of SF3B1 mutations in myelodysplastic syndromes and myelodysplastic/myeloproliferative neoplasms

Peter J Campbell, Michael R Stratton, Luca Malcovati, 2011, Blood.

Direct Transcriptional Consequences of Somatic Mutation in Breast Cancer

A. Børresen-Dale, M. Stratton, P. Campbell, 2016, Cell reports.

Characterization of the human cell line TE671.

M. Stratton, P. Lantos, C. Cooper, 1989, Carcinogenesis.

An interstitial tandem duplication of 9p23-24 coexists with a mutation in the BRCA2 gene in the germ line of three brothers with breast cancer.

M. Stratton, M. Schwab, P. Schlag, 1998, Cancer research.

Molecular Biology for Oncologists

M. Stratton, J. Yarnold, T. McMillan, 1993 .

SETD2 loss-of-function promotes renal cancer branched evolution through replication stress and impaired DNA repair

Z. Szallasi, M. Stratton, N. Matthews, 2015, Oncogene.

Screening for BRCA2 mutations in 81 Dutch breast–ovarian cancer families

M. Stratton, G. Bignell, J. Klijn, 1999, British Journal of Cancer.

Tobacco exposure and somatic mutations in normal human bronchial epithelium

M. Stratton, P. Campbell, A. Menzies, 2019, Nature.

Novel candidate cancer genes identified by a large-scale cross-species comparative oncogenomics approach.

T. Hubbard, M. Stratton, G. Bignell, 2010, Cancer research.

Functional patient-derived organoid screenings identify MCLA-158 as a therapeutic EGFR × LGR5 bispecific antibody with efficacy in epithelial tumors

M. Stratton, H. Clevers, J. Tabernero, 2022, Nature Cancer.

Author response: The Human Cell Atlas

Fabian J Theis, Jay W. Shin, D. Pe’er, 2017 .

BRAF and RAS mutations in human lung cancer and melanoma.

Richard Wooster, Helen Davies, Michael R Stratton, 2002, Cancer research.

Origins and functional consequences of somatic mitochondrial DNA mutations in human cancer

Bin Tean Teh, Andrew Menzies, Keiran Raine, 2014, eLife.

The V617F JAK2 mutation is uncommon in cancers and in myeloid malignancies other than the classic myeloproliferative disorders.

M. Stratton, P. Futreal, R. Wooster, 2005, Blood.

The evolution of two transmissible cancers in Tasmanian devils

Hannes P. Eggertsson, Edward F. Harry, Fergal J. Martin, 2022, bioRxiv.

Embryonal precursors of Wilms tumor

Matthew D. Young, M. Stratton, P. Campbell, 2019, Science.

M. Stratton, P. Futreal, R. Wooster, 2002, Cancer research.

DICER1 syndrome: clarifying the diagnosis, clinical features and management implications of a pleiotropic tumour predisposition syndrome

A. Nicholson, M. Stratton, N. Rahman, 2011, Journal of Medical Genetics.

Resource A Landscape of Pharmacogenomic Interactions in Cancer Graphical Abstract Highlights

Emanuel J. V. Gonçalves, M. Stratton, G. Bignell, 2016 .

BRCA 1 and BRCA 2 Mutations in Breast Cancer Families with Multiple Primary Cancers 1

S. Seal, M. Stratton, T. Rebbeck, 2000 .

Germline mutations of the BRCA1 gene in breast and ovarian cancer families provide evidence for a genotype–phenotype correlation

D. Clayton, D. Easton, S. Seal, 1995, Nature Genetics.

Signatures of mutational processes in human cancer this access benefits you. Your matters

David C. Jones, M. Meyerson, R. Eils, 2013 .

Tissue-Biased Expansion of DNMT3A-Mutant Clones in a Mosaic Individual Is Associated with Conserved Epigenetic Erosion.

M. Stratton, P. Campbell, J. Mill, 2020, Cell stem cell.

Hereditary predisposition to breast cancer.

M. Stratton, R. Wooster, Michael R. Stratton, 1996, Current opinion in genetics & development.

Genome-wide screening for complete genetic loss in prostate cancer by comparative hybridization onto cDNA microarrays

Colin Campbell, Sandra Edwards, Ian Giddings, 2003, Oncogene.

Whole genome DNA copy number changes identified by high density oligonucleotide arrays

Keith W. Jones, Richard Wooster, Michael R Stratton, 2004, Human Genomics.

Mutations in ZDHHC9, which encodes a palmitoyltransferase of NRAS and HRAS, cause X-linked mental retardation associated with a Marfanoid habitus.

Andrew Menzies, Keiran Raine, Sarah Edkins, 2007, American journal of human genetics.

CASK mutations are frequent in males and cause X-linked nystagmus and variable XLMR phenotypes

M. Shaw, J. Gécz, M. Stratton, 2010, European Journal of Human Genetics.

Lessons learnt from large-scale exon re-sequencing of the X chromosome

J. Gécz, M. Stratton, A. Whibley, 2009, Human molecular genetics.

Mutations in CUL4B, which encodes a ubiquitin E3 ligase subunit, cause an X-linked mental retardation syndrome associated with aggressive outbursts, seizures, relative macrocephaly, central obesity, hypogonadism, pes cavus, and tremor.

Andrew Menzies, Keiran Raine, Sarah Edkins, 2007, American journal of human genetics.

Architectures of somatic genomic rearrangement in human cancer amplicons at sequence-level resolution.

Andrew Menzies, Sarah Edkins, Richard Wooster, 2007, Genome research.

Identification of the breast cancer susceptibility gene BRCA2

Julian Peto, Peter Devilee, Rosalind Eeles, 1996, Nature.

Estrogen Receptor Status Could Modulate the Genomic Pattern in Familial and Sporadic Breast Cancer

Tara L. Naylor, M. Stratton, N. Rahman, 2007, Clinical Cancer Research.

A missense mutation in the BRCA2 gene in three siblings with ovarian cancer.

A. Ashworth, S. Seal, M. Stratton, 1998, British Journal of Cancer.

Identification and characterization of two novel JARID1C mutations: suggestion of an emerging genotype–phenotype correlation

J. Gécz, M. Stratton, P. Futreal, 2010, European Journal of Human Genetics.

A hypermutation phenotype and somatic MSH6 mutations in recurrent human malignant gliomas after alkylator chemotherapy.

Tracy T Batchelor, Richard Lugg, Andrew Menzies, 2006, Cancer research.

BRCA2 mutations in primary breast and ovarian cancers

Sheila Seal, Richard Wooster, Alan Ashworth, 1996, Nature Genetics.

Somatic KIT mutations occur predominantly in seminoma germ cell tumors and are not predictive of bilateral disease: Report of 220 tumors and review of literature

M. Stratton, R. Huddart, D. Easton, 2008, Genes, chromosomes & cancer.

Soft tissue tumours: the genetic basis of development.

M. Stratton, C. Cooper, 1991, Carcinogenesis.

The International Testicular Cancer Linkage Consortium: a clinicopathologic descriptive analysis of 461 familial malignant testicular germ cell tumor kindred.

D. Bishop, M. Stratton, K. Heimdal, 2010, Urologic oncology.

Somatic mutations of KIT in familial testicular germ cell tumours

Katherine M. Tucker, D. Easton, M. Stratton, 2004, British Journal of Cancer.

Alcohol and endogenous aldehydes damage chromosomes and mutate stem cells

M. Stratton, S. Nik-Zainal, Lee Mulderrig, 2018, Nature.

Contribution of germline MLH1 and MSH2 mutations to lobular carcinoma in situ of the breast.

M. Stratton, B. Gusterson, R. Houlston, 2001, Cancer letters.

Evidence for susceptibility genes to familial Wilms tumour in addition to WT1, FWT1 and FWT2

M. Stratton, N. Rahman, A. Shelling, 2000, British Journal of Cancer.

The familial Wilms' tumour susceptibility gene, FWT1, may not be a tumour suppressor gene

M. Stratton, N. Rahman, P. Tonin, 1997, Oncogene.

Somatic Evolution in Non-neoplastic IBD-Affected Colon

M. Parkes, M. Stratton, P. Campbell, 2020, Cell.

The mutational profile and clonal landscape of the inflammatory bowel disease affected colon

M. Parkes, M. Stratton, P. Campbell, 2019, bioRxiv.

NIHMS662581-supplement-Supplementary data

Pardeep Kumar, Elizabeth Anderson, Jon W. Teague, 2016 .

Familial breast cancer

M. Stratton, R. Eeles, D. Goldgar, 1996 .

Linkage analysis of 56 multiplex families excludes the Cowden disease genePTEN as a major contributor to familial breast cancer

D. Easton, S. Seal, M. Stratton, 1999, Journal of medical genetics.

Variation of risks of breast and ovarian cancer associated with different germline mutations of the BRCA2 gene

S. Seal, M. Stratton, P. Russell, 1997, Nature Genetics.

Constitutional mutation in exon 8 of the p53 gene in a patient with multiple primary tumours: molecular and immunohistochemical findings.

M. Stratton, R. Eeles, D. Easton, 1993, Oncogene.

Corrigendum: Analysis of the genetic phylogeny of multifocal prostate cancer identifies multiple independent clonal expansions in neoplastic and morphologically normal prostate tissue

L. Matthews, M. Stratton, D. Berney, 2015, Nature Genetics.

Localisation of susceptibility genes for familial testicular germ cell tumour

M. Stratton, D. Easton, D. Bishop, 2003, APMIS : acta pathologica, microbiologica, et immunologica Scandinavica.

Mutagenicity of acrylamide and glycidamide in human TP53 knock-in (Hupki) mouse embryo fibroblasts

M. Stratton, J. Kucab, V. Arlt, 2020, Archives of Toxicology.

The Human Cell Atlas White Paper

Roland Eils, Hans Clevers, Mary Carmichael, 2018, 1810.05192.

Low-penetrance susceptibility to breast cancer due to CHEK2*1100delC in noncarriers of BRCA1 or BRCA2 mutations

Nazneen Rahman, Carel Meijers, Julian Peto, 2002, Nature Genetics.

Mechanisms of APOBEC3 mutagenesis in human cancer cells

Erik N. Bergstrom, M. Stratton, L. Alexandrov, 2022, Nature.

Structure of the met protein and variation of met protein kinase activity among human tumour cell lines.

M. Stratton, C. Cooper, P. Tempest, 1988, British Journal of Cancer.

Somatic mutations of the histone H3K27 demethylase, UTX, in human cancer

Bin Tean Teh, Chai Yin Kok, Andrew Menzies, 2009, Nature Genetics.

Personally Tailored Risk Prediction of AML Based on Comprehensive Genomic and Clinical Data

M. Stratton, P. Campbell, L. Bullinger, 2015 .

Extensive phylogenies of human development reveal variable embryonic patterns

M. Stratton, P. Campbell, I. Martincorena, 2020, bioRxiv.

Disruption at the Ptchd1 Locus on Xp22.11 in Autism Spectrum Disorder and Intellectual Disability Nih Public Access

Chi-Chung Hui, Andre Franke, Geraldine Dawson, 2010 .

Mutational signatures: the patterns of somatic mutations hidden in cancer genomes

M. Stratton, L. Alexandrov, 2014, Current opinion in genetics & development.

A novel Gln358Glu mutation in ectodysplasin A associated with X‐linked dominant incisor hypodontia

T. Pemberton, P. Patel, M. Stratton, 2007, American journal of medical genetics. Part A.

The mutational landscape of human somatic and germline cells

M. Stratton, P. Campbell, A. Menzies, 2020, Nature.

Mutation and association analysis of in breast cancer susceptibility

S. Seal, M. Stratton, N. Rahman, 2020 .

Breast cancer susceptibility: a complex disease unravels.

M. Stratton, R. Wooster, M. Stratton, 1995, Trends in genetics : TIG.

Comprehensive analysis of indels in whole-genome microsatellite regions and microsatellite instability across 21 cancer types

Satoru Miyano, Yuichi Shiraishi, Seiya Imoto, 2018, bioRxiv.

Mutations in the RSK2(RPS6KA3) gene cause Coffin–Lowry syndrome and nonsyndromic X‐linked mental retardation

M. Stratton, R. Wooster, S. Edkins, 2006, Clinical genetics.

Inherited MUTYH mutations cause elevated somatic mutation rates and distinctive mutational signatures in normal human cells

M. Stratton, P. Campbell, I. Martincorena, 2021, Nature Communications.

Mutational landscape of normal epithelial cells in Lynch Syndrome patients

M. Stratton, P. Campbell, I. Martincorena, 2022, Nature Communications.

High Throughput Targeted Gene Sequencing in 738 Myelodysplastic Syndromes Patients Reveals Novel Oncogenic Genes, Rare Driver Mutations and Complex Molecular Signatures with Potential Impact for Patient Diagnosis and Prognosis in the Clinic

M. Stratton, P. Campbell, M. Cazzola, 2012 .

Allelotype of uterine leiomyomas.

M. Stratton, D. Easton, R. Barfoot, 1999, Cancer genetics and cytogenetics.

The p53 gene in human cancer.

M. Stratton, 1992, European journal of cancer.

The Genomic Landscape of TEL-AML1+ (ETV6-RUNX1) Acute Lymphoblastic Leukaemia

M. Stratton, P. Futreal, P. Campbell, 2011 .

Prediction of BRCA1 Status in Patients with Breast Cancer Using Estrogen Receptor and Basal Phenotype

Julian Peto, Ute Hamann, Peter Devilee, 2005, Clinical Cancer Research.

143 INVITED Evolution of the Cancer Genome

M. Stratton, 2011 .

Arena syndrome is caused by a missense mutation in PLP1

M. Stratton, P. Tarpey, R. Stevenson, 2009, American journal of medical genetics. Part A.

Recurrent histone mutations in T‐cell acute lymphoblastic leukaemia

Matthew D. Young, M. Stratton, P. Campbell, 2018, British journal of haematology.

Prevalence of BRCA1 and BRCA2 gene mutations in patients with early-onset breast cancer.

S. Seal, M. Stratton, N. Rahman, 1999, Journal of the National Cancer Institute.

Exclusion of biglycan mutations in a cohort of patients with neuromuscular disorders

J. Gécz, M. Stratton, P. Tarpey, 2008, Neuromuscular Disorders.

The BRAF gene is frequently mutated in malignant melanoma.

M. Stratton, P. Futreal, R. Wooster, 2004, Journal of drugs in dermatology : JDD.

Genomic heterogeneity in primary breast cancer: Clinical implications.

P. Lønning, M. Stratton, P. Campbell, 2014 .

Submicroscopic duplications of the hydroxysteroid dehydrogenase HSD17B10 and the E3 ubiquitin ligase HUWE1 are associated with mental retardation.

Peter Marynen, Rodney Scott, Patrick S Tarpey, 2008, American journal of human genetics.

Multifactorial analysis of differences between sporadic breast cancers and cancers involving BRCA1 and BRCA2 mutations.

M. Stratton, M. J. van de Vijver, J. Chang-Claude, 1998, Journal of the National Cancer Institute.

Ovarian cancer risk in BRCA1 carriers is modified by the HRAS1 variable number of tandem repeat (VNTR) locus

M. Stratton, B. Ponder, T. Rebbeck, 1996, Nature Genetics.

A case of cerebellar medulloblastoma with a single chromosome abnormality.

M. Stratton, C. Cooper, B. Reeves, 1991, Cancer genetics and cytogenetics.

Haplotype and phenotype analysis of nine recurrent BRCA2 mutations in 111 families: results of an international study.

M. King, D. Easton, M. Stratton, 1998, American journal of human genetics.

Genetic heterogeneity and localization of a familial breast-ovarian cancer gene on chromosome 17q12-q21.

M. Stratton, B. Ponder, D. Easton, 1993, American journal of human genetics.

Pathology of familial breast cancer: differences between breast cancers in carriers of BRCA1 or BRCA2 mutations and sporadic cases

M. Stratton, 1997, The Lancet.

Familial craniofacial fibrous dysplasia: absence of linkage toGNAS1 and the gene for cherubism

M. Stratton, S. Edkins, J. Mangion, 2000, Journal of medical genetics.

Genetics of non-medullary thyroid cancer.

M. Stratton, R. Houlston, 1995, QJM : monthly journal of the Association of Physicians.

Transmissible Dog Cancer Genome Reveals the Origin and History of an Ancient Cell Lineage

Peter J. Campbell, Michael R. Stratton, Robin A. Weiss, 2014, Science.

Identification of nine new susceptibility loci for testicular cancer, including variants near DAZL and PRDM14

Nazneen Rahman, Julian Peto, Rosalind Eeles, 2013, Nature Genetics.

Chromosomally unstable mouse tumours have genomic alterations similar to diverse human cancers

L. Chin, M. Stratton, A. Protopopov, 2007, Nature.

X-linked protocadherin 19 mutations cause female-limited epilepsy and cognitive impairment

Andrew Menzies, Sarah Edkins, Sara Widaa, 2008, Nature Genetics.

DNA sequence analysis of known cancer genes in the NCI-60 cell lines.

J. Weinstein, M. Stratton, R. Wooster, 2006 .

TO JMG Biallelic BRCA 2 mutations are associated with multiple malignancies in childhood including familial Wilms tumour

S. Seal, M. Stratton, A. Renwick, 2005 .

Cytogenetic abnormalities in human ependymomas

M. Stratton, C. Cooper, P. Lantos, 1989, International journal of cancer.

The original Lujan syndrome family has a novel missense mutation (p.N1007S) in the MED12 gene

M. Stratton, P. Futreal, S. Edkins, 2007, Journal of Medical Genetics.

Recurrent rearrangements of FOS and FOSB define osteoblastoma

Matthew D. Young, M. Stratton, C. Antonescu, 2018, Nature Communications.

Tumor exome analysis reveals neoantigen-specific T-cell reactivity in an ipilimumab-responsive melanoma.

M. Stratton, S. Behjati, T. Schumacher, 2013, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Genomics of Drug Sensitivity in Cancer (GDSC): a resource for therapeutic biomarker discovery in cancer cells

Sridhar Ramaswamy, Howard Lightfoot, Nidhi Bindal, 2012, Nucleic Acids Res..

Hypomorphic temperature-sensitive alleles of NSDHL cause CK syndrome.

Steven J. M. Jones, Ryan D. Morin, Richard A. Moore, 2010, American journal of human genetics.

COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer

Mingming Jia, Nidhi Bindal, Rebecca Shepherd, 2010, Nucleic Acids Res..

Recurrent mutation of IGF signalling genes and distinct patterns of genomic rearrangement in osteosarcoma

Daniel Baumhoer, Inigo Martincorena, Roberto Tirabosco, 2017, Nature Communications.

Intra-tumour diversification in colorectal cancer at the single-cell level

Matthew D. Young, M. Stratton, P. Campbell, 2018, Nature.

Tissue-specific mutation accumulation in human adult stem cells during life

Hans Clevers, Nobuo Sasaki, Edwin Cuppen, 2016, Nature.

Variants near DMRT1, TERT and ATF7IP are associated with testicular germ cell cancer

Deborah Hughes, Nazneen Rahman, Panagiotis Deloukas, 2010, Nature Genetics.

A genome-wide association study of testicular germ cell tumor

Deborah Hughes, Nazneen Rahman, Panagiotis Deloukas, 2009, Nature Genetics.

The Y deletion gr/gr and susceptibility to testicular germ cell tumor.

M. Pike, M. Stratton, D. Forman, 2005, American journal of human genetics.

Genome-wide linkage screen for testicular germ cell tumour susceptibility loci.

M. Stratton, D. Forman, K. Heimdal, 2006, Human molecular genetics.

Abstract IA007: The mutational landscape of normal human endometrial epithelium

M. Stratton, P. Campbell, D. Leongamornlert, 2021, Functional Genomics and Proteomics.

Mutations in the p53 gene in schistosomal bladder cancer: a study of 92 tumours from Egyptian patients and a comparison between mutational spectra from schistosomal and non-schistosomal urothelial tumours.

M. Stratton, S. Venitt, P. Biggs, 1995, Carcinogenesis.

1. The Genetics of Testicular Germ Cell Tumours

D. Easton, M. Stratton, D. Bishop, 2002 .

The Genetics of Testicular Germ Cell Tumours

M. Stratton, D. Easton, D. Bishop, 2002 .

Localization to Xq27 of a susceptibility gene for testicular germ-cell tumours

S. Seal, M. Stratton, D. Forman, 2000, Nature Genetics.

The pathology of familial breast cancer: histological features of cancers in families not attributable to mutations in BRCA1 or BRCA2.

M. Stratton, M. J. van de Vijver, J. Chang-Claude, 2000, Clinical cancer research : an official journal of the American Association for Cancer Research.

Using gene carrier probability to select high risk families for identifying germline mutations in breast cancer susceptibility genes.

M. Stratton, J. Chang-Claude, H. Becher, 1998, Journal of medical genetics.

Multi-stage genome-wide association study identifies new susceptibility locus for testicular germ cell tumour on chromosome 3q25.

S. Seal, M. Stratton, N. Rahman, 2015, Human molecular genetics.

Detection of point mutations in N-ras and K-ras genes of human embryonal rhabdomyosarcomas using oligonucleotide probes and the polymerase chain reaction.

M. Stratton, C. Cooper, B. Gusterson, 1989, Cancer research.

Structural alterations of the RB1 gene in human soft tissue tumours.

M. Stratton, B. Gusterson, C. Fisher, 1989, British Journal of Cancer.

COSMIC: the catalogue of somatic mutations in cancer

C. Cole, M. Stratton, P. Campbell, 2011, Genome Biology.

Imidazopurinones are markers of physiological genomic damage linked to DNA instability and glyoxalase 1-associated tumour multidrug resistance

M. Stratton, T. Santarius, Paul J Thornalley, 2010, Nucleic acids research.

Combined hereditary and somatic mutations of replication error repair genes result in rapid onset of ultra-hypermutated cancers

Roland Arnold, Richard G Grundy, Daniele Merico, 2015, Nature Genetics.

RNA editing of human microRNAs

Anton J. Enright, Richard Wooster, Michael R Stratton, 2006, Genome Biology.

Processed pseudogenes acquired somatically during cancer development

Andrew Menzies, Adam P. Butler, Jon W. Teague, 2014, Nature Communications.

Mutation and association analysis of GEN1 in breast cancer susceptibility

S. Seal, M. Stratton, N. Rahman, 2010, Breast Cancer Research and Treatment.

A survey of homozygous deletions in human cancer genomes.

E. Birney, M. Stratton, P. Futreal, 2005, Proceedings of the National Academy of Sciences of the United States of America.

BRAF gene is somatically mutated but does not make a major contribution to malignant melanoma susceptibility: the Italian Melanoma Intergroup Study.

M. Stratton, G. Botti, P. Ascierto, 2004, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Distinct H3F3A and H3F3B driver mutations define chondroblastoma and giant cell tumor of bone

M. Stratton, P. Futreal, P. Campbell, 2013, Nature Genetics.

Feedback Circuit among INK4 Tumor Suppressors Constrains Human Glioblastoma Development

Webster K. Cavenee, Yonghong Xiao, Michael R. Stratton, 2008, Cancer cell.

Frequent mutation of the major cartilage collagen gene COL2A1 in chondrosarcoma

David Beare, Andrew Menzies, Keiran Raine, 2013, Nature Genetics.

Comparative performances of machine learning methods for classifying Crohn Disease patients using genome-wide genotyping data

Judy H. Cho, John P. Ferguson, G. Wainrib, 2019, Scientific Reports.

COSMIC: exploring the world's knowledge of somatic mutations in human cancer

Mingming Jia, Nidhi Bindal, Simon A. Forbes, 2014, Nucleic Acids Res..

Sequence analysis of the protein kinase gene family in human testicular germ‐cell tumors of adolescents and adults

Richard Lugg, Andrew Menzies, Keiran Raine, 2006, Genes, chromosomes & cancer.

AutoCSA, an algorithm for high throughput DNA sequence variant detection in cancer genomes

Andrew M. Jenkinson, C. Greenman, Rebecca Shepherd, 2007, Bioinform..

The emerging landscape of breast cancer susceptibility

Nazneen Rahman, Michael R Stratton, M. Stratton, 2007, Nature Genetics.

HRDetect is a predictor of BRCA1 and BRCA2 deficiency based on mutational signatures

E. Birney, A. Børresen-Dale, M. Stratton, 2017, Nature Medicine.

HRDetect : A mutational signature based predictor of BRCA 1 and BRCA 2 deficiency

Alastair, Steven, Anne, 2017 .

The BRC repeats are conserved in mammalian BRCA2 proteins.

A. Ashworth, M. Stratton, R. Wooster, 1997, Human molecular genetics.

The genetics of breast cancer susceptibility.

M. Stratton, N. Rahman, Michael R. Stratton, 1998, Annual review of genetics.

Mutations in UPF3B, a member of the nonsense-mediated mRNA decay complex, cause syndromic and nonsyndromic mental retardation

J. Gécz, M. Stratton, P. Futreal, 2007, Nature Genetics.

Cancer risks in two large breast cancer families linked to BRCA2 on chromosome 13q12-13.

D E Goldgar, D. Easton, M. Stratton, 1997, American journal of human genetics.

A germline mutation in the androgen receptor gene in two brothers with breast cancer and Reifenstein syndrome

M. Stratton, B. Ponder, R. Wooster, 1992, Nature Genetics.

SLC9A6 mutations cause X-linked mental retardation, microcephaly, epilepsy, and ataxia, a phenotype mimicking Angelman syndrome.

J. Gécz, M. Stratton, P. Futreal, 2008, American journal of human genetics.

Somatic mutations reveal asymmetric cellular dynamics in the early human embryo

M. Hurles, A. Børresen-Dale, M. Stratton, 2017, Nature.

Somatic mutation landscapes at single-molecule resolution

M. Stratton, P. Campbell, E. Laurenti, 2021, Nature.

C. elegans whole-genome sequencing reveals mutational signatures related to carcinogens and DNA repair deficiency

Peter J. Campbell, Michael R. Stratton, Keiran Raine, 2014, Genome research.

M. Stratton, P. Campbell, K. Raine, 2014 .

Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomes

Andrew Menzies, Adam P. Butler, Jon W. Teague, 2014, Science.

APOBEC mutagenesis is a common process in normal human small intestine

M. Stratton, P. Campbell, I. Martincorena, 2023, Nature Genetics.

A polymorphic stop codon in BRCA2

M. Stratton, B. Ponder, A. Dunning, 1996, Nature Genetics.

Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells

Carlos Caldas, Fengtang Yang, Rosalind Eeles, 2015, Genome research.

Constitutional and somatic rearrangement of chromosome 21 in acute lymphoblastic leukaemia

Peter J. Campbell, Michael R. Stratton, Ben Robinson, 2014, Nature.

Single-cell paired-end genome sequencing reveals structural variation per cell cycle

M. Stratton, P. Futreal, P. Campbell, 2013, Nucleic acids research.

A mutational signature in gastric cancer suggests therapeutic strategies

Serena Nik-Zainal, Michael R Stratton, Suet Yi Leung, 2015, Nature Communications.

Patterns of somatic structural variation in human cancer genomes

Nuno A. Fonseca, Gary D Bader, Benjamin J. Raphael, 2020, Nature.

A comprehensive model for familial breast cancer incorporating BRCA1, BRCA2 and other genes

N E Day, N. Day, M. Stratton, 2002, British Journal of Cancer.

Somatic mutation rates scale with lifespan across mammals

David C. Jones, M. Stratton, P. Campbell, 2021, Nature.

Tandem duplication of chromosomal segments is common in ovarian and breast cancer genomes

M. Stratton, P. Futreal, P. Campbell, 2012, The Journal of pathology.

Cloning, chromosomal mapping and expression pattern of the mouse Brca2 gene.

A. Ashworth, M. Stratton, R. Wooster, 1997, Human molecular genetics.

Recurrent PTPRB and PLCG1 mutations in angiosarcoma

M. Stratton, A. Protopopov, P. Futreal, 2014, Nature Genetics.

High-throughput epitope discovery reveals frequent recognition of neo-antigens by CD4+ T cells in human melanoma

Michael R Stratton, Arno Velds, Hergen Spits, 2014, Nature Medicine.

Universal Patterns of Selection in Cancer and Somatic Tissues

Chuang Tan, Michelle D Wang, M. Stratton, 2018, Cell.

The gene for cherubism maps to chromosome 4p16.3.

A. Sigurdsson, M. Stratton, N. Rahman, 1999, American journal of human genetics.

Genome-Wide Mutational Signatures of Aristolochic Acid and Its Application as a Screening Tool

P. A. Futreal, M. Stratton, W. Sung, 2013, Science Translational Medicine.

Somatic mutations and clonal dynamics in healthy and cirrhotic human liver

Inigo Martincorena, Peter J Campbell, Michael R Stratton, 2019, Nature.

Somatic evolution and global expansion of an ancient transmissible cancer lineage

Eleni Fotopoulou, Michael R. Stratton, Ludmil B. Alexandrov, 2019, Science.

SigProfilerMatrixGenerator: a tool for visualizing and exploring patterns of small mutational events

Mark Barnes, Michael R. Stratton, Ludmil B. Alexandrov, 2019, BMC Genomics.

Whole-Genome Sequencing Reveals Breast Cancers with Mismatch Repair Deficiency.

Alain Viari, Sandro Morganella, Alastair Thompson, 2017, Cancer research.

Short inverted repeats contribute to localized mutability in human somatic cells

M. Stratton, S. Morganella, S. Nik-Zainal, 2017, Nucleic acids research.

Genome-wide chemical mutagenesis screens allow unbiased saturation of the cancer genome and identification of drug resistance mutations

M. Stratton, L. Stebbings, G. Bignell, 2017, bioRxiv.

Title A mutational signature in gastric cancer suggests therapeuticstrategies

M. Stratton, S. Nik-Zainal, L. Alexandrov, 2015 .

Breast cancer genome and transcriptome integration implicates specific mutational signatures with immune cell infiltration

E. Birney, M. Ringnér, A. Børresen-Dale, 2016, Nature Communications.

The landscape of somatic mutation in normal colorectal epithelial cells

M. Stratton, P. Campbell, I. Martincorena, 2018, Nature.

Tubio retrotransposition in cancer genomes Extensive transduction of nonrepetitive DNA mediated by L 1

M. Stratton, P. Futreal, P. Campbell, 2014 .

Mutation analysis of 24 known cancer genes in the NCI-60 cell line set

Richard Lugg, Andrew Menzies, Michael R. Stratton, 2006, Molecular Cancer Therapeutics.

The Catalogue of Somatic Mutations in Cancer (COSMIC)

S A Forbes, G Bhamra, S Bamford, 2008, Current protocols in human genetics.

Refined mapping of X-linked reticulate pigmentary disorder and sequencing of candidate genes

J. Gécz, A. Zinn, M. Stratton, 2008, Human Genetics.

Genomic evidence supports a clonal diaspora model for metastases of esophageal adenocarcinoma

M. Stratton, A. Hindmarsh, D. Wedge, 2018, bioRxiv.

Case of interstitial 12q deletion in association with Wilms tumor.

M. Stratton, N. Rahman, R. Barfoot, 2001, American journal of medical genetics.

Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples

Nuno A. Fonseca, Gary D Bader, Benjamin J. Raphael, 2020, Nature Communications.

A genome wide linkage search for breast cancer susceptibility genes

S. Seal, M. Stratton, N. Rahman, 2006, Genes, chromosomes & cancer.

Convergent somatic mutations in metabolism genes in chronic liver disease

Stanley W. K. Ng, M. Stratton, P. Campbell, 2021, Nature.

Variants in CHEK 2 Other than 1100 delC Do Not Make a Major Contribution to Breast Cancer Susceptibility

S. Seal, M. Stratton, N. Rahman, 2003 .

Genome-wide association study identifies five new breast cancer susceptibility loci

Deborah Hughes, Nazneen Rahman, William Tapper, 2010, Nature Genetics.

A Pathogenic Mosaic TP53 Mutation in Two Germ Layers Detected by Next Generation Sequencing

M. Stratton, P. Tarpey, S. Behjati, 2014, PloS one.

A Small Cell Lung Cancer Genome Reports Complex Tobacco Exposure Signatures Europe Pmc Funders Group

Minna, E. Birney, K. McKernan, 2022 .

The frequency of germ-line mutations in the breast cancer predisposition genes BRCA1 and BRCA2 in familial prostate cancer. The Cancer Research Campaign/British Prostate Group United Kingdom Familial Prostate Cancer Study Collaborators.

M. Stratton, B. Ponder, R. Eeles, 2000, Cancer research.

Evolution and lineage dynamics of a transmissible cancer in Tasmanian devils

Menna E. Jones, M. Stratton, D. Wedge, 2020, PLoS biology.

Constitutional translocation breakpoint mapping by genome-wide paired-end sequencing identifies HACE1 as a putative Wilms tumour susceptibility gene

M. Stratton, N. Rahman, P. Stephens, 2009, Journal of Medical Genetics.

Data mining using the Catalogue of Somatic Mutations in Cancer BioMart

Mingming Jia, Nidhi Bindal, Rebecca Shepherd, 2011, Database J. Biol. Databases Curation.

COSMIC, curating the cancer variome

Simon A. Forbes, Jon W. Teague, Michael R. Stratton, 2008, AIMM.

Evidence for a familial Wilms' tumour gene (FWT1) on chromosome 17q12–q21

Nazneen Rahman, Michael R. Stratton, Jerry Pelletier, 1996, Nature Genetics.

Clonal dynamics of haematopoiesis across the human lifespan

Emily F. Calderbank, M. Stratton, P. Campbell, 2021, Nature.

Universal Patterns of Selection in Cancer and Somatic Tissues

M. Stratton, P. Campbell, P. Loo, 2017, bioRxiv.

Genome resequencing and genetic variation

Michael Stratton, M. Stratton, 2008, Nature Biotechnology.

Somatic mutations in human cancer: insights from resequencing the protein kinase gene family.

M. Stratton, P. Futreal, R. Wooster, 2005, Cold Spring Harbor symposia on quantitative biology.

Fine-scale survey of X chromosome copy number variants and indels underlying intellectual disability.

M. Shaw, J. Gécz, M. Stratton, 2010, American journal of human genetics.

Genetic alterations in ‘normal’ luminal and myoepithelial cells of the breast

M. Stratton, S. Lakhani, N. Collins, 1999, The Journal of pathology.

Author Correction: Landscape of somatic mutations in 560 breast cancer whole-genome sequences

E. Birney, M. Ringnér, A. Børresen-Dale, 2019, Nature.

Development, maturation, and maintenance of human prostate inferred from somatic mutations

M. Stratton, P. Campbell, I. Martincorena, 2021, Cell stem cell.

Familial male breast cancer is not linked to the BRCA1 locus on chromosome 17q

M. King, S. Seal, M. Stratton, 1994, Nature Genetics.

Mutations in the guanine nucleotide exchange factor gene IQSEC2 cause nonsyndromic intellectual disability

M. Shaw, J. Gécz, M. Stratton, 2010, Nature Genetics.

Loss of the Mismatch Repair Protein MSH6 in Human Glioblastomas Is Associated with Tumor Progression during Temozolomide Treatment

P. A. Futreal, M. Stratton, A. Iafrate, 2007, Clinical Cancer Research.

A whole-genome sequence and transcriptome perspective on HER2-positive breast cancers

Alain Viari, Thomas Bachelot, Michael R. Stratton, 2016, Nature Communications.

Journeys into the genome of cancer cells

M. Stratton, 2013, EMBO molecular medicine.

BRCA1 and BRCA2 germline mutations in Sardinian breast cancer families and their implications for genetic counseling.

M. Stratton, J. Mangion, A. Cossu, 2002, Annals of oncology : official journal of the European Society for Medical Oncology.

BRCA1 and BRCA2 mutation frequency in women evaluated in a breast cancer risk evaluation clinic.

S. Seal, M. Stratton, F. Couch, 2002, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Rapid detection of DNA sequence variants by conformation-sensitive capillary electrophoresis.

M. Stratton, R. Wooster, N. Collins, 2000, Genomics.

Absence of evidence for a familial breast cancer susceptibility gene at chromosome 8p12-p22

S. Seal, M. Stratton, N. Rahman, 2000, Oncogene.

Screening for ESR mutations in breast and ovarian cancer patients

A. Børresen-Dale, M. Stratton, R. Wooster, 1997, Human mutation.

Recent advances in understanding of genetic susceptibility to breast cancer.

M. Stratton, Michael R. Stratton, 1996, Human molecular genetics.

Loss of heterozygosity in sporadic breast tumours at the BRCA2 locus on chromosome 13q12-q13.

P. Devilee, J. Weissenbach, M. Stratton, 1995, British Journal of Cancer.

Identification of the familial cylindromatosis tumour-suppressor gene

A. Ashworth, S. Seal, M. Stratton, 2000, Nature Genetics.

Familial cylindromatosis (turban tumour syndrome) gene localised to chromosome 16q12–q13: evidence for its role as a tumour suppressor gene

M. Stratton, R. Wooster, D. Easton, 1995, Nature Genetics.

COSMIC (the Catalogue of Somatic Mutations in Cancer): a resource to investigate acquired mutations in human cancer

Mingming Jia, Nidhi Bindal, Simon A. Forbes, 2009, Nucleic Acids Res..

Loss of heterozygosity in lobular carcinoma in situ of the breast

M. Stratton, J. Sloane, N. Collins, 1995, Clinical molecular pathology.

A gene for lymphedema-distichiasis maps to 16q24.3.

A. Sigurdsson, M. Stratton, N. Rahman, 1999, American journal of human genetics.

gene MED12 missense mutation (p.N1007S) in the The original Lujan syndrome family has a novel

M. Stratton, S. Edkins, J. Teague, 2008 .

Extensive phylogenies of human development inferred from somatic mutations

M. Stratton, P. Campbell, I. Martincorena, 2021, Nature.

GLO1—A novel amplified gene in human cancer

M. Stratton, P. Futreal, T. Santarius, 2010, Genes, chromosomes & cancer.

Whole exome sequencing of adenoid cystic carcinoma.

M. Stratton, P. Futreal, P. Campbell, 2013, The Journal of clinical investigation.

Increased somatic mutation burdens in normal human cells due to defective DNA polymerases

M. Stratton, P. Campbell, I. Martincorena, 2021, Nature Genetics.

Inherited susceptibility to colorectal adenomas and carcinomas: evidence for a new predisposition gene on 15q14-q22.

S. Seal, M. Stratton, N. Rahman, 1999, Gastroenterology.

Low frequency of somatic mutations in the LKB1/Peutz-Jeghers syndrome gene in sporadic breast cancer.

S. Seal, M. Stratton, G. Bignell, 1998, Cancer research.

Recurrent intragenic rearrangements of EGFR and BRAF in soft tissue tumors of infants

David T. W. Jones, David C. Jones, A. Rosenwald, 2018, Nature Communications.

LKB1/KRAS mutant lung cancers constitute a genetic subset of NSCLC with increased sensitivity to MAPK and mTOR signalling inhibition

M. Stratton, T. Santarius, S. Edkins, 2009, British Journal of Cancer.

Use of cancer‐specific genomic rearrangements to quantify disease burden in plasma from patients with solid tumors

M. Stratton, P. Futreal, P. Campbell, 2010, Genes, chromosomes & cancer.

Partially methylated domains are hypervariable in breast cancer and fuel widespread CpG island hypermethylation

M. Ringnér, A. Børresen-Dale, M. Stratton, 2018, Nature Communications.

Genomics and the continuum of cancer care.

Michael R Stratton, Ultan McDermott, J. Downing, 2011, The New England journal of medicine.

Life without mismatch repair

M. Stratton, P. Campbell, M. Gerstung, 2021, bioRxiv.

The exon 13 duplication in the BRCA1 gene is a founder mutation present in geographically diverse populations. The BRCA1 Exon 13 Duplication Screening Group.

M. Beckmann, T. Sellers, M. Stratton, 2000, American journal of human genetics.

Lobular carcinoma in situ of the breast is not caused by constitutional mutations in the E-cadherin gene

S. Seal, M. Stratton, N. Rahman, 2000, British Journal of Cancer.

Combinations of PARP Inhibitors with Temozolomide Drive PARP1 Trapping and Apoptosis in Ewing’s Sarcoma

M. Stratton, U. McDermott, S. Barthorpe, 2015, PloS one.

High throughput DNA sequence variant detection by conformation sensitive capillary electrophoresis and automated peak comparison.

M. Stratton, P. Futreal, R. Wooster, 2006, Genomics.

Somatic structural rearrangements in genetically engineered mouse mammary tumors

M. Stratton, P. Futreal, P. Campbell, 2010, Genome Biology.

Recurrent deletion of ZNF630 at Xp11.23 is not associated with mental retardation

R. Pfundt, J. Gécz, M. Stratton, 2010, American journal of medical genetics. Part A.

Germline mutations in BRCA1 and BRCA2 in breast-ovarian families from a breast cancer risk evaluation clinic.

S. Seal, M. Stratton, B. Weber, 2001, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Misidentified cell

M. Stratton, C. Cooper, B. Reeves, 1989, Nature.

Mutations in the BRWD3 gene cause X-linked mental retardation associated with macrocephaly.

K. Friend, M. Shaw, J. Gécz, 2007, American journal of human genetics.

The Gene for Cherubism Maps to Chromosome

A. Sigurdsson, M. Stratton, N. Rahman, 2001 .

The driver landscape of sporadic chordoma

Matthew D. Young, M. Stratton, T. Nielsen, 2017, Nature Communications.

604 Cancer Genomics, Epigenetics and Genomic Instability. Mutational Processes Shaping the Genomes of Twenty-one Breast Cancers

M. Stratton, P. Futreal, P. Campbell, 2012 .

Analysis of the DND1 gene in men with sporadic and familial testicular germ cell tumors

D. Bishop, M. Stratton, K. Heimdal, 2008, Genes, chromosomes & cancer.

Oligosaccharyltransferase-subunit mutations in nonsyndromic mental retardation.

J. Gécz, M. Stratton, P. Futreal, 2008, American journal of human genetics.

Familial testicular cancer: lack of evidence for trinucleotide repeat expansions and association with PKD1 in one family

M. Stratton, C. Larsson, R. Huddart, 1999, Journal of medical genetics.

Does a genotoxic carcinogen contribute to human breast cancer? The value of mutational spectra in unravelling the aetiology of cancer.

M. Stratton, S. Venitt, P. Biggs, 1993, Mutagenesis.

Frequent activating FGFR2 mutations in endometrial carcinomas parallel germline mutations associated with craniosynostosis and skeletal dysplasia syndromes

P. Pollock, J. Trent, M. Stratton, 2007, Oncogene.

Common BRCA1 variants and susceptibility to breast and ovarian cancer in the general population.

D. Clayton, D. Easton, M. Stratton, 1997, Human molecular genetics.

Evaluation of Fanconi Anemia genes in familial breast cancer predisposition.

S. Seal, M. Stratton, N. Rahman, 2003, Cancer research.

Extraction and Enzymatic Amplification of DNA from Paraffin-Embedded Specimens

M. Stratton, C. Cooper, 1991 .

Confirmation of FWT1 as a Wilms’ tumour susceptibility gene and phenotypic characteristics of Wilms’ tumour attributable to FWT1

Michael R. Stratton, Dick Variend, Richard Grundy, 1998, Human Genetics.

Absence of methylation of CpG dinucleotides within the promoter of the breast cancer susceptibility gene BRCA2 in normal tissues and in breast and ovarian cancers.

M. Stratton, R. Wooster, N. Collins, 1997, British Journal of Cancer.

Reliable detection of somatic mutations in solid tissues by laser-capture microdissection and low-input DNA sequencing

Inigo Martincorena, Luiza Moore, Peter J Campbell, 2020, Nature Protocols.

The APOBEC3A deaminase drives episodic mutagenesis in cancer cells

M. Stratton, L. Alexandrov, M. Petljak, 2021, bioRxiv.

Biallelic BRCA2 mutations are associated with multiple malignancies in childhood including familial Wilms tumour

S. Seal, M. Stratton, N. Rahman, 2005, Journal of Medical Genetics.

HPC2/ELAC2 polymorphisms and prostate cancer risk: analysis by age of onset of disease

M. Stratton, R. Eeles, S. Edwards, 2002, British Journal of Cancer.

Poon Application as a Screening Tool Genome-Wide Mutational Signatures of Aristolochic Acid and Its

M. Stratton, P. Futreal, W. Sung, 2013 .

Large scale immunoediting is not a hallmark of human melanoma

M. Stratton, S. Behjati, T. Schumacher, 2016 .

Corrigendum: Signatures of mutational processes in human cancer

Roland Eils, Natalie Jäger, Adam P. Butler, 2013, Nature.

Use of tumor exome analysis to reveal neo-antigen-specific T-cell reactivity in ipilimumab-responsive melanoma.

M. Stratton, S. Behjati, T. Schumacher, 2013 .

Familial nontoxic multinodular thyroid goiter locus maps to chromosome 14q but does not account for familial nonmedullary thyroid cancer.

M. Stratton, G. Bignell, W. Foulkes, 1997, American journal of human genetics.

Comprehensive molecular characterization of mitochondrial genomes in human cancers

Nuno A. Fonseca, Gary D Bader, Benjamin J. Raphael, 2017, bioRxiv.

Heterozygosity for mutations in the ataxia telangiectasia gene is not a major cause of radiotherapy complications in breast cancer patients.

S. Seal, M. Stratton, N. Rahman, 1998, British Journal of Cancer.

Mutational signatures in esophageal squamous cell carcinoma from eight countries with varying incidence

David C. Jones, Lia S. Campos, R. Malekzadeh, 2021, Nature Genetics.

Extended Data Figure 5

M. Stratton, P. Campbell, P. Stephens, 2014 .

Author Correction: Pan-cancer analysis of whole genomes

Nuno A. Fonseca, Gary D Bader, Benjamin J. Raphael, 2023, Nature.

Predisposition gene identification in common cancers by exome sequencing: insights from familial breast cancer

Nazneen Rahman, Elise Ruark, Anthony Renwick, 2012, Breast Cancer Research and Treatment.

A Multicenter Study of Cancer Incidence in CHEK2 1100delC Mutation Carriers

S. Seal, M. Stratton, N. Rahman, 2006, Cancer Epidemiology Biomarkers & Prevention.

Mutations in the gene encoding the Sigma 2 subunit of the adaptor protein 1 complex, AP1S2, cause X-linked mental retardation.

J. Gécz, M. Stratton, P. Futreal, 2006, American journal of human genetics.

Dinucleotide repeat polymorphism at the SIS locus.

M. Stratton, P. J. Mitchell, H. Patterson, 1990, Nucleic acids research.

Population dynamics of normal human blood inferred from somatic mutations

M. Stratton, P. Campbell, Mairi S. Shepherd, 2018, Nature.

Linkage and LOH studies in 19 cylindromatosis families show no evidence of genetic heterogeneity and refine the CYLD locus on chromosome 16q12–q13

S. Seal, M. Stratton, R. Siebert, 2000, Human Genetics.

The cylindromatosis gene (cyld1) on chromosome 16q may be the only tumour suppressor gene involved in the development of cylindromas.

M. Stratton, S. Lakhani, J. Burn, 1996, Oncogene.

Evaluation of linkage of breast cancer to the putative BRCA3 locus on chromosome 13q21 in 128 multiple case families from the Breast Cancer Linkage Consortium

S. Seal, M. Stratton, N. Rahman, 2002, Proceedings of the National Academy of Sciences of the United States of America.

The A-T gene does not make a major contribution to familial breast cancer

M. Stratton, B. Ponder, R. Wooster, 1993 .

Sex differences in oncogenic mutational processes

Nuno A. Fonseca, Gary D Bader, Benjamin J. Raphael, 2019, Nature Communications.

Mutation in Rpa1 results in defective DNA double-strand break repair, chromosomal instability, and cancer in mice

Benjamin J. Raphael, P. Pevzner, M. Stratton, 2004 .

A 45-year follow-up of kindred 107 and the search for BRCA2.

M. Stratton, D. Easton, S. Neuhausen, 1995, Journal of the National Cancer Institute. Monographs.

Terminology for carcinoma-in-situ of the breast

M. Stratton, C. Quinn, J. Sloane, 1996, The Lancet.

Recurrent intragenic rearrangements of EGFR and BRAF in soft tissue tumors of infants

David T. W. Jones, A. Rosenwald, M. Stratton, 2018, Nature Communications.

ALTERED c-H-ras GENE IN NON-NEOPLASTIC TISSUE

M. Stratton, C. Cooper, D. Wynford‐Thomas, 1989, The Lancet.

Whole-genome sequencing identifies recurrent mutations in chronic lymphocyticleukaemia

A. Valencia, R. Guigó, X. Estivill, 2011 .

Tobacco smoking and somatic mutations in human bronchial epithelium

M. Stratton, P. Campbell, A. Menzies, 2020, Nature.

The Genetics Feature Article of Familial Breast Cancer and Their Practical Implications

M. Stratton, R. Eeles, D. Easton, 1994 .

The genetics of familial breast cancer and their practical implications.

M. Stratton, R. Eeles, D. Easton, 1994, European journal of cancer.

Mutagenicity of 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine (N-OH-PhIP) in human TP53 knock-in (Hupki) mouse embryo fibroblasts.

M. Stratton, J. Kucab, V. Arlt, 2020, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

BRCA1 and BRCA2 mutations in breast cancer families with multiple primary cancers.

S. Seal, M. Stratton, T. Rebbeck, 2000, Clinical cancer research : an official journal of the American Association for Cancer Research.

In vitro differential sensitivity of melanomas to phenothiazines is based on the presence of codon 600 BRAF mutation

J. Weinstein, M. Stratton, S. Durinck, 2008, Molecular Cancer Therapeutics.

Recurrent rearrangements of FOS and FOSB define osteoblastoma

Matthew D. Young, M. Stratton, C. Antonescu, 2018, Nature Communications.

The driver landscape of sporadic chordoma

Matthew D. Young, M. Stratton, T. Nielsen, 2017, Nature Communications.

Genetic heterogeneity in familial Wilms tumour

Michael R. Stratton, Nazneen Rahman, Elizabeth A. Rapley, 1999 .

Clonal Dynamics of Normal Haematopoiesis with Human Ageing

Emily F. Calderbank, M. Stratton, E. Laurenti, 2021, Blood.

A comprehensive analysis of MNG1, TCO1, fPTC, PTEN, TSHR, and TRKA in familial nonmedullary thyroid cancer: confirmation of linkage to TCO1.

M. Stratton, G. Bignell, W. Foulkes, 2001, The Journal of clinical endocrinology and metabolism.

Natural history of Christianson syndrome

M. Stratton, P. Tarpey, R. Stevenson, 2010, American journal of medical genetics. Part A.

Epilepsy and mental retardation limited to females with PCDH19 mutations can present de novo or in single generation families

Michael R Stratton, N. Brown, I. Scheffer, 2009, Journal of Medical Genetics.

Younger age-at-diagnosis for familial malignant testicular germ cell tumor

Bingshu E. Chen, M. Stratton, K. Heimdal, 2009, Familial Cancer.

A novel X-linked trichothiodystrophy associated with a nonsense mutation in RNF113A

K. Friend, J. Gécz, M. Stratton, 2015, Journal of Medical Genetics.

Supplementary file 1.

Jack A. Taylor, M. Stratton, D. Hayes, 2011 .

Detection of transforming genes by transfection of DNA from primary soft-tissue tumours.

M. Stratton, C. Cooper, B. Gusterson, 1991, Oncogene.

Corrigendum: Adjuvant-dependent innate and adaptive immune signatures of risk of SIVmac251 acquisition

M. Stratton, S. Behjati, T. Schumacher, 2016, Nature Medicine.

Gene-gene interactions in breast cancer susceptibility.

Deborah Hughes, Peter Donnelly, Jonathan Berg, 2012, Human molecular genetics.

Normal tissue clones preceding childhood kidney cancer

Naima, Matthew D. Young, Suzanne, 2019 .

An international report on bacterial communities in esophageal squamous cell carcinoma

Charles J. Vaske, R. Malekzadeh, M. Meyerson, 2021, bioRxiv.

Testicular microlithiasis as a familial risk factor for testicular germ cell tumour

M. Stratton, R. Huddart, D. Easton, 2007, British Journal of Cancer.

Sequencing analysis of BRAF mutations in human cancers.

M. Stratton, R. Wooster, A. Futreal, 2006, Methods in Enzymology.

A physical analysis of the Y chromosome shows no additional deletions, other than Gr/Gr, associated with testicular germ cell tumour

D. Easton, M. Stratton, R. Huddart, 2007, British Journal of Cancer.

Identification of nine new susceptibility loci for testicular cancer, including variants near DAZL and PRDM14

S. Seal, M. Stratton, N. Rahman, 2013 .

The Human Cell Atlas

Fabian J Theis, Jay W. Shin, Michael J. T. Stubbington, 2017, bioRxiv.

Supplementary file 3.

Jack A. Taylor, M. Stratton, D. Hayes, 2014 .

Mining cancer genomes in COSMIC

C. Cole, M. Stratton, P. Campbell, 2012, BMC Proceedings.

Genetic alterations in ‘normal’ luminal and myoepithelial cells of the breast

M. Stratton, S. Lakhani, N. Collins, 1999, The Journal of pathology.

Assigning mutational signatures to individual samples and individual somatic mutations with SigProfilerAssignment

M. Stratton, L. Alexandrov, P. Brennan, 2023, bioRxiv.

Mutation allele burden remains unchanged in chronic myelomonocytic leukaemia responding to hypomethylating agents

M. Stratton, F. Artiguenave, L. Alexandrov, 2016, Nature Communications.

Universal Patterns of Selection in Cancer and Somatic Tissues

M. Stratton, P. Campbell, P. Loo, 2017, Cell.

Somatic mutations reveal asymmetric cellular dynamics in the early human embryo

M. Hurles, A. Børresen-Dale, M. Stratton, 2017, Nature.

Corrigendum: Distinct H3F3A and H3F3B driver mutations define chondroblastoma and giant cell tumor of bone

M. Stratton, P. Futreal, P. Campbell, 2014, Nature Genetics.

Author Correction: The repertoire of mutational signatures in human cancer

M. Stratton, Arnoud Boot, S. Morganella, 2023, Nature.

Screening for ESR mutations in breast and ovarian cancer patients

A. Børresen-Dale, M. Stratton, R. Wooster, 1997, Human mutation.

Corrigendum: Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells.

Carlos Caldas, Fengtang Yang, Rosalind Eeles, 2016, Genome research.

Corrigendum: Mutations in FRMD7, a newly identified member of the FERM family, cause X-linked idiopathic congenital nystagmus

M. Stratton, P. Futreal, R. Wooster, 2011, Nature Genetics.

Penetrance of mutations in the familial Wilms tumor gene FWT1.

M. Stratton, N. Rahman, W. Foulkes, 2000, Journal of the National Cancer Institute.

The Human Cell Atlas White Paper

Evan Z. Macosko, Jay W. Shin, Allon M. Klein, 2018, 1810.05192.

The landscape of cancer genes and mutational processes in breast cancer

A. Børresen-Dale, M. Stratton, M. J. van de Vijver, 2012, Nature.

Intra-tumour diversification in colorectal cancer at the single-cell level

Hans Clevers, Nobuo Sasaki, Peter J. Campbell, 2018, Nature.

Fine-scale survey of X chromosome copy number variants and indels underlying intellectual disability.

M. Shaw, J. Gécz, M. Stratton, 2010, American journal of human genetics.

Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomes

A. Børresen-Dale, M. Stratton, M. J. van de Vijver, 2014, Science.

Multi-stage genome-wide association study identifies new susceptibility locus for testicular germ cell tumour on chromosome 3q25.

S. Seal, M. Stratton, N. Rahman, 2015, Human molecular genetics.

Universal Patterns of Selection in Cancer and Somatic Tissues

M. Stratton, P. Campbell, P. Loo, 2017, Cell.

Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells

Fengtang Yang, A. Børresen-Dale, M. Stratton, 2015, Genome research.

Distinct Genomic Profiles in Hereditary Breast Tumors Identified by Array-based Comparative Genomic Hybridization

Tara L. Naylor, M. Ringnér, M. Stratton, 2022 .

Use of cancer‐specific genomic rearrangements to quantify disease burden in plasma from patients with solid tumors

M. Stratton, P. Futreal, P. Campbell, 2010, Genes, chromosomes & cancer.

Extended Data Table 1

Peter J. Campbell, Michael R. Stratton, Philip J. Stephens, 2014 .