P. Thomas

发表

Automated Detection of Nucleoplasmic Bridges for DNA Damage Scoring in Binucleated Cells

Philip Thomas, Changming Sun, Pascal Vallotton, 2010, 2010 20th International Conference on Pattern Recognition.

A review of genome mutation and Alzheimer's disease.

Philip Thomas, Michael Fenech, M. Fenech, 2006, Mutagenesis.

M. Fenech, P. Thomas, 2009 .

Grape seed polyphenols and curcumin reduce genomic instability events in a transgenic mouse model for Alzheimer's disease.

M. Fenech, P. Thomas, N. O’Callaghan, 2009, Mutation research.

Buccal Cytome Biomarkers and Their Association with Plasma Folate, Vitamin B12 and Homocysteine in Alzheimer's Disease

M. Fenech, P. Thomas, 2015, Lifestyle Genomics.

Telomere length in healthy adults is positively associated with polyunsaturated fatty acids, including arachidonic acid, and negatively with saturated fatty acids.

M. Fenech, P. Thomas, V. Dhillon, 2020, The journals of gerontology. Series A, Biological sciences and medical sciences.

Comparison of DNA damage and repair following radiation challenge in buccal cells and lymphocytes using single‐cell gel electrophoresis

M. Fenech, P. Thomas, V. Dhillon, 2004, International journal of radiation biology.

Automation of the buccal micronucleus cytome assay using laser scanning cytometry.

M. Fenech, P. Thomas, W. Leifert, 2011, Methods in cell biology.

Shorter telomere length in carriers of APOE-ε4 and high plasma concentration of glucose, glyoxal and other advanced glycation end products (AGEs).

M. Fenech, P. Thomas, V. Dhillon, 2020, The journals of gerontology. Series A, Biological sciences and medical sciences.

State of the art survey of the buccal micronucleus assay--a first stage in the HUMN(XL) project initiative.

M. Fenech, P. Thomas, M. Kirsch‐Volders, 2009, Mutagenesis.

Buccal micronucleus cytome assay.

M. Fenech, P. Thomas, 2011, Methods in molecular biology.

APOE ε4 carriers have a greater propensity to glycation and sRAGE which is further influenced by RAGE G82S polymorphism.

M. Fenech, P. Thomas, V. Dhillon, 2019, The journals of gerontology. Series A, Biological sciences and medical sciences.

Genome instability biomarkers and blood micronutrient risk profiles associated with mild cognitive impairment and Alzheimer's disease.

M. Fenech, P. Thomas, S. Lee, 2015, Mutation research.

High Content, Multi-Parameter Analyses in Buccal Cells to Identify Alzheimer's Disease.

M. Fenech, P. Thomas, C. Rowe, 2016, Current Alzheimer research.

Biomarkers of Alzheimer’s Disease Risk in Peripheral Tissues; Focus on Buccal Cells

M. Fenech, P. Thomas, R. Martins, 2014, Current Alzheimer research.

Buccal micronucleus cytome biomarkers may be associated with Alzheimer's disease.

M. Fenech, P. Thomas, J. Faunt, 2007, Mutagenesis.

Molecular mechanisms of micronucleus, nucleoplasmic bridge and nuclear bud formation in mammalian and human cells.

M. Fenech, P. Thomas, M. Kirsch‐Volders, 2011, Mutagenesis.

Folate and methionine metabolism in autism: a systematic review.

M. Fenech, P. Thomas, M. Angley, 2010, The American journal of clinical nutrition.

Methylenetetrahydrofolate reductase, common polymorphisms, and relation to disease.

M. Fenech, P. Thomas, 2008, Vitamins and hormones.

The potential role of the antioxidant and detoxification properties of glutathione in autism spectrum disorders: a systematic review and meta-analysis

M. Fenech, P. Thomas, M. Angley, 2012, Nutrition & Metabolism.

In vivo evaluation of the genotoxic effects of Hyrax auxiliary orthodontic appliances containing silver-soldered joints.

P. Thomas, J. Henriques, L. Menezes, 2015, Mutation research. Genetic toxicology and environmental mutagenesis.

Cytotoxicity and genotoxicity of orthodontic bands with or without silver soldered joints.

M. Fenech, P. Thomas, J. Henriques, 2014, Mutation research. Genetic toxicology and environmental mutagenesis.

Zinc deficiency or excess within the physiological range increases genome instability and cytotoxicity, respectively, in human oral keratinocyte cells

M. Fenech, P. Thomas, P. Zalewski, 2012, Genes & Nutrition.

Buccal micronucleus cytome assay

Claudia Bolognesi, Errol Zeiger, Philip Thomas, 2009, Nature Protocols.

Chromosome 17 and 21 aneuploidy in buccal cells is increased with ageing and in Alzheimer's disease.

M. Fenech, P. Thomas, 2007, Mutagenesis.

Folate deficiency induces aneuploidy in human lymphocytes in vitro-evidence using cytokinesis-blocked cells and probes specific for chromosomes 17 and 21.

M. Fenech, P. Thomas, Xu Wang, 2004, Mutation research.

Association of micronucleus frequency with neurodegenerative diseases.

M. Fenech, P. Thomas, F. Coppedè, 2011, Mutagenesis.

The role of zinc in genomic stability.

M. Fenech, P. Thomas, P. Zalewski, 2012, Mutation research.

The HUman MicroNucleus project on eXfoLiated buccal cells (HUMN(XL)): the role of life-style, host factors, occupational exposures, health status, and assay protocol.

M. Fenech, P. Thomas, E. Zeiger, 2011, Mutation research.

A quantitative real-time PCR method for absolute telomere length.

Philip Thomas, Michael Fenech, M. Fenech, 2008, BioTechniques.

The effect of zinc sulphate and zinc carnosine on genome stability and cytotoxicity in the WIL2-NS human lymphoblastoid cell line.

M. Fenech, P. Thomas, R. Graham, 2011, Mutation research.

Infant birth outcomes are associated with DNA damage biomarkers as measured by the cytokinesis block micronucleus cytome assay: the DADHI study

M. Fenech, P. Thomas, J. Owens, 2017, Mutagenesis.

Use of the lymphocyte cytokinesis-block micronucleus assay in occupational biomonitoring of genome damage caused by in vivo exposure to chemical genotoxins: Past, present and future.

M. Fenech, P. Thomas, S. Bonassi, 2016, Mutation research.

Telomere length in white blood cells, buccal cells and brain tissue and its variation with ageing and Alzheimer's disease

M. Fenech, P. Thomas, N. O. Callaghan, 2008, Mechanisms of Ageing and Development.

The HUMN and HUMNxL international collaboration projects on human micronucleus assays in lymphocytes and buccal cells--past, present and future.

M. Fenech, P. Thomas, M. Kirsch‐Volders, 2011, Mutagenesis.

Effect of dietary intervention on human micronucleus frequency in lymphocytes and buccal cells.

Philip Thomas, Michael Fenech, M. Fenech, 2011, Mutagenesis.

Zinc supplementation influences genomic stability biomarkers, antioxidant activity, and zinc transporter genes in an elderly Australian population with low zinc status.

M. Fenech, P. Thomas, P. Zalewski, 2015, Molecular nutrition & food research.

Potential role of folate in pre-eclampsia.

M. Fenech, P. Thomas, J. Owens, 2015, Nutrition reviews.

Genetic polymorphisms of genes involved in DNA repair and metabolism influence micronucleus frequencies in human peripheral blood lymphocytes.

M. Fenech, P. Thomas, M. Kirsch‐Volders, 2011, Mutagenesis.

Folic acid deficiency increases chromosomal instability, chromosome 21 aneuploidy and sensitivity to radiation-induced micronuclei.

M. Fenech, P. Thomas, J. Turner, 2005, Mutation research.

The HUMNxl scoring criteria for different cell types and nuclear anomalies in the buccal micronucleus cytome assay - an update and expanded photogallery.

M. Fenech, P. Thomas, C. Bolognesi, 2013, Mutation research.

Workers exposed to wood dust have an increased micronucleus frequency in nasal and buccal cells: results from a pilot study.

M. Fenech, P. Thomas, B. Danuser, 2014, Mutagenesis.

Consumption of Grape Seed Extract Prevents Amyloid-β Deposition and Attenuates Inflammation in Brain of an Alzheimer’s Disease Mouse

M. Fenech, P. Thomas, Yanjiang Wang, 2009, Neurotoxicity Research.

Extracellular amyloid beta 42 causes necrosis, inhibition of nuclear division, and mitotic disruption under both folate deficient and folate replete conditions as measured by the cytokinesis‐block micronucleus cytome assay

M. Fenech, P. Thomas, S. Lee, 2014, Environmental and molecular mutagenesis.

Lack of Evidence for Genomic Instability in Autistic Children as Measured by the Cytokinesis‐Block Micronucleus Cytome Assay

M. Fenech, P. Thomas, C. King, 2015, Autism research : official journal of the International Society for Autism Research.

Necrosis is increased in lymphoblastoid cell lines from children with autism compared with their non-autistic siblings under conditions of oxidative and nitrosative stress.

M. Fenech, P. Thomas, A. Esterman, 2013, Mutagenesis.

Inter-laboratory consistency and variability in the buccal micronucleus cytome assay depends on biomarker scored and laboratory experience: results from the HUMNxl international inter-laboratory scoring exercise

M. Fenech, P. Thomas, S. Bonassi, 2016, Mutagenesis.

The buccal cytome and micronucleus frequency is substantially altered in Down's syndrome and normal ageing compared to young healthy controls.

M. Fenech, P. Thomas, T. Gruner, 2008, Mutation research.

Changes in buccal cytome biomarkers in relation to ageing and Alzheimer’s Disease.

P. Thomas, 2008 .

Methylenetetrahydrofolate reductase C677T polymorphism, folic acid and riboflavin are important determinants of genome stability in cultured human lymphocytes.

M. Fenech, P. Thomas, K. Umegaki, 2004, The Journal of nutrition.

Nutrient-Gene Interactions Methylenetetrahydrofolate Reductase C 677 T Polymorphism , Folic Acid and Riboflavin Are Important Determinants of Genome Stability in Cultured Human Lymphocytes

M. Fenech, P. Thomas, K. Umegaki, 2003 .

Chromosomal DNA damage in APOE ɛ4 carriers and noncarriers does not appear to be different

M. Fenech, P. Thomas, Ann Chua, 2015, Environmental and molecular mutagenesis.

The APOE 4 allele is also associated with increased risk for other neurodegenerative diseases such as Parkinson ’ s disease , along with a poorer recovery and survival outcome following stroke and head trauma [

M. Fenech, P. Thomas, Ann Chua, 2015 .

Effect of docosahexaenoic acid and furan fatty acids on cytokinesis block micronucleus cytome assay biomarkers in astrocytoma cell lines under conditions of oxidative stress

M. Fenech, P. Thomas, Ann Chua, 2014, Environmental and molecular mutagenesis.

Buccal micronucleus cytome assay: results of an intra- and inter-laboratory scoring comparison.

M. Fenech, P. Thomas, C. Bolognesi, 2015, Mutagenesis.

Micronucleus induction and chromosome loss in transformed human white cells indicate clastogenic and aneugenic action of the cyanobacterial toxin, cylindrospermopsin.

M. Fenech, P. Thomas, A. Humpage, 2000, Mutation research.

Altered cytological parameters in buccal cells from individuals with mild cognitive impairment and Alzheimer's disease

M. Fenech, P. Thomas, R. Martins, 2014, Cytometry. Part A : the journal of the International Society for Analytical Cytology.

Low Magnesium in Conjunction with High Homocysteine and Less Sleep Accelerates Telomere Attrition in Healthy Elderly Australian

M. Fenech, P. Thomas, V. Dhillon, 2023, International journal of molecular sciences.

Nucleoplasmic bridges are a sensitive measure of chromosome rearrangement in the cytokinesis-block micronucleus assay.

M. Fenech, P. Thomas, K. Umegaki, 2003, Mutagenesis.

Effect of common polymorphisms in folate uptake and metabolism genes on frequency of micronucleated lymphocytes in a South Australian cohort.

M. Fenech, P. Thomas, V. Dhillon, 2009, Mutation research.

Cytoprotective and pro-apoptotic activities of native Australian herbs polyphenolic-rich extracts.

M. Fenech, P. Thomas, I. Konczak, 2013, Food chemistry.

Cytokinesis-block micronucleus cytome assay in lymphocytes.

M. Fenech, P. Thomas, 2011, Methods in molecular biology.

Normal human lymphocytes exhibit a wide range of methionine-dependency which is related to altered cell division but not micronucleus frequency.

M. Fenech, P. Thomas, J. Crott, 2001, Mutagenesis.

Chromosomal DNA damage measured using the cytokinesis‐block micronucleus cytome assay is significantly associated with cognitive impairment in South Australians

M. Fenech, P. Thomas, J. Hecker, 2015, Environmental and molecular mutagenesis.

Oleic Acid Status Positively Correlates with the Soluble Receptor for Advanced Glycation End-Products (sRAGE) in Healthy Adults Who Are Homozygous for G Allele of RAGE G82S Polymorphism

M. Fenech, P. Thomas, V. Dhillon, 2023, Cells.

A blood-based biomarker panel indicates IL-10 and IL-12/23p40 are jointly associated as predictors of β-amyloid load in an AD cohort

Blaine R. Roberts, M. Fenech, P. Thomas, 2017, Scientific Reports.

Red Blood Cell Fatty Acid Profiles Are Significantly Altered in South Australian Mild Cognitive Impairment and Alzheimer’s Disease Cases Compared to Matched Controls

P. Thomas, V. Dhillon, P. Deo, 2023, International journal of molecular sciences.

The association of N ε-Carboxymethyllysine with polyunsaturated and saturated fatty acids in healthy individuals.

M. Fenech, P. Thomas, V. Dhillon, 2021, The journals of gerontology. Series A, Biological sciences and medical sciences.

Buccal micronucleus cytome assay

M. Fenech, P. Thomas, M. Kirsch‐Volders, 2009, Nature Protocols.

Effect of common polymorphisms in folate uptake and metabolism genes on frequency of micronucleated lymphocytes in a South Australian cohort.

M. Fenech, P. Thomas, V. Dhillon, 2009, Mutation research.

Folate and methionine metabolism in autism: a systematic review.

M. Fenech, P. Thomas, M. Angley, 2010, The American journal of clinical nutrition.

Zinc deficiency or excess within the physiological range increases genome instability and cytotoxicity, respectively, in human oral keratinocyte cells

M. Fenech, P. Thomas, P. Zalewski, 2012, Genes & Nutrition.

Telomere length in white blood cells, buccal cells and brain tissue and its variation with aging and Alzheimer's disease

M. Fenech, P. Thomas, 2010, Alzheimer's & Dementia.

Sleep duration, Health Promotion Index (HPI), sRAGE and ApoE-ε4 genotype are associated with telomere length (TL) in healthy elderly Australians.

M. Fenech, P. Thomas, V. Dhillon, 2021, The journals of gerontology. Series A, Biological sciences and medical sciences.

Buccal micronucleus cytome biomarkers may be associated with Alzheimer's disease

M. Fenech, P. Thomas, 2010, Alzheimer's & Dementia.