S. Melquist

发表

Integrated Systems Approach Identifies Genetic Nodes and Networks in Late-Onset Alzheimer’s Disease

L. Tran, Bin Zhang, C. Gaiteri, 2013, Cell.

GAB2 Alleles Modify Alzheimer's Risk in APOE ɛ4 Carriers

Winnie S. Liang, G. Alexander, D. Stephan, 2007, Neuron.

GAB2 alleles modify Alzheimer's risk in APOE epsilon4 carriers.

Winnie S. Liang, G. Alexander, D. Stephan, 2007, Neuron.

Identification of the genetic basis for complex disorders by use of pooling-based genomewide single-nucleotide-polymorphism association studies.

Rebecca F. Halperin, Nils Homer, D. Stephan, 2007, American journal of human genetics.

Mutations in progranulin are a major cause of ubiquitin-positive frontotemporal lobar degeneration.

S. Melquist, M. Mesulam, B. Boeve, 2006, Human molecular genetics.

Arabidopsis PAI gene arrangements, cytosine methylation and expression.

S. Melquist, J. Bender, B. Luff, 1999, Genetics.

Evidence for an association between KIBRA and late-onset Alzheimer's disease

Richard J. Caselli, Gene E. Alexander, Daniel Bandy, 2010, Neurobiology of Aging.

Analysis of UBQLN1 Variants in a Polish Alzheimer’s Disease Patient: Control Series

S. Melquist, M. Barcikowska, K. Safranow, 2008, Dementia and Geriatric Cognitive Disorders.

High-density SNP haplotyping suggests altered regulation of tau gene expression in progressive supranuclear palsy.

G. Schellenberg, S. Melquist, D. Dickson, 2005, Human molecular genetics.

An Internal Rearrangement in an Arabidopsis Inverted Repeat Locus Impairs DNA Methylation Triggered by the Locus

S. Melquist, J. Bender, 2004, Genetics.

Whole genome association analysis shows that ACE is a risk factor for Alzheimer's disease and fails to replicate most candidates from Meta-analysis.

D. Stephan, S. Melquist, A. Myers, 2010, International journal of molecular epidemiology and genetics.

Study of a Swiss dopa-responsive dystonia family with a deletion in GCH1

D. Stephan, S. Melquist, M. Farrer, 2008, Neurology.

Title : Study of a Swiss dopa-responsive dystonia family with a deletion in GCH 1 : redefining DYT 14 as DYT 5

D. Stephan, S. Melquist, J. Kachergus, 2022 .

RNA Interference Targeting Hepatic Angiopoietin-Like Protein 3 Results in Prolonged Reductions in Plasma Triglycerides and LDL-C in Human Subjects

S. Melquist, J. Knowles, P. Clifton, 2019 .

Identiﬁcation of a Novel Risk Locus for Progressive Supranuclear Palsy by a Pooled Genomewide Scan of 500,288 Single-Nucleotide Polymorphisms

Jason J. Corneveaux, D. Stephan, S. Melquist, 2007 .

RNAi inhibition of angiopoietin-like protein 3 (ANGPTL3) with ARO-ANG3 mimics the lipid and lipoprotein profile of familial combined hypolipidemia

S. Melquist, J. Knowles, P. Clifton, 2020 .

Identification of a novel risk locus for progressive supranuclear palsy by a pooled genomewide scan of 500,288 single-nucleotide polymorphisms.

Richard J Caselli, John V Pearson, Irene Litvan, 2007, American journal of human genetics.

Mutations in progranulin cause tau-negative frontotemporal dementia linked to chromosome 17

S. Melquist, D. Neary, B. Boeve, 2006, Nature.

Transcription from an upstream promoter controls methylation signaling from an inverted repeat of endogenous genes in Arabidopsis.

S. Melquist, J. Bender, 2003, Genes & development.

A family with tau-negative frontotemporal dementia and neuronal intranuclear inclusions linked to chromosome 17.

S. Melquist, H. Feldman, A. Sadovnick, 2006, Brain : a journal of neurology.

Abstract 15751: Pharmacodynamic Effect of ARO-ANG3, an Investigational RNA Interference Targeting Hepatic Angiopoietin-like Protein 3, in Patients With Hypercholesterolemia

S. Melquist, J. Knowles, D. Gaudet, 2020 .

Targeting Factor 12 (F12) with a Novel RNAi Delivery Platform As a Prophylactic Treatment for Hereditary Angioedema (HAE)

Darren H. Wakefield, S. Melquist, D. Lewis, 2016 .

Common dysregulation network in the human prefrontal cortex underlies two neurodegenerative diseases

Xia Yang, Guoping Fan, Eric E Schadt, 2014 .

Preclinical development and phase 1 trial of a novel siRNA targeting lipoprotein(a)

Saptarsi M. Haldar, S. Melquist, G. Watts, 2022, Nature Medicine.

Preclinical development and phase 1 trial of a novel siRNA targeting lipoprotein(a)

Saptarsi M. Haldar, S. Melquist, Hong Wang, 2022, Nature Medicine.

Discovery of 6-(Fluoro-(18)F)-3-(1H-pyrrolo[2,3-c]pyridin-1-yl)isoquinolin-5-amine ([(18)F]-MK-6240): A Positron Emission Tomography (PET) Imaging Agent for Quantification of Neurofibrillary Tangles (NFTs).

Talakad G. Lohith, S. Melquist, L. Gantert, 2016, Journal of medicinal chemistry.

Risk‐reducing effect of education in Alzheimer's disease

S. Melquist, S. Lydersen, I. Saltvedt, 2008, International journal of geriatric psychiatry.

Autosomal dominant dystonia-plus with cerebral calcifications

S. Melquist, R. Uitti, J. Allanson, 2006, Neurology.

Reduced Expression of Angiopoietin-Like Protein 3 via RNA Interference with ARO-ANG3 Produces Prolonged Reductions in LDL-C and Triglycerides in Dyslipidemic Patients

S. Melquist, J. Knowles, D. Gaudet, 2020 .

Abstract 12594: Pharmacodynamic Effect of ARO-APOC3, an Investigational Hepatocyte-targeted RNA Interference Therapeutic Targeting Apolipoprotein C3, in Patients With Hypertriglyceridemia and Multifactorial Chylomicronemia

S. Melquist, J. Knowles, D. Gaudet, 2020 .

APOE ε4 lowers age at onset and is a high risk factor for Alzheimer's disease; A case control study from central Norway

Stian Lydersen, Ingvild Saltvedt, Olav Sletvold, 2008, BMC neurology.

LRRK2 mutations are not common in Alzheimer's disease

S. Melquist, M. Farrer, S. Sando, 2005, Mechanisms of Ageing and Development.

Common dysregulation network in the human prefrontal cortex underlies two neurodegenerative diseases

Andrew D. Johnson, Bin Zhang, J. McElwee, 2014 .

RNA interference targeting ANGPTL3 for triglyceride and cholesterol lowering: phase 1 basket trial cohorts

S. Melquist, J. Knowles, D. Gaudet, 2023, Nature Medicine.

Changes in core biomarkers in cerebrospinal fluid and cognitive ability in patients with Alzheimer's disease: A two-year longitudinal study

S. Melquist, G. Bråthen, S. Sando, 2012, Alzheimer's & Dementia.

Evidence for an association between KIBRA and late-onset Alzheimer's disease

Jason J. Corneveaux, Winnie S. Liang, G. Alexander, 2010, Neurobiology of Aging.

Molecular Systems Biology Peer Review Process File Common Dysregulation Network in the Human Prefrontal Cortex Underlies Two Neurodegenerative Diseases Transaction Report

Andrew D. Johnson, Bin Zhang, J. McElwee, 2022 .