J. Lamb

发表

Integrated Systems Approach Identifies Genetic Nodes and Networks in Late-Onset Alzheimer’s Disease

L. Tran, Bin Zhang, C. Gaiteri, 2013, Cell.

Systems analysis of eleven rodent disease models reveals an inflammatome signature and key drivers

Yudong D. He, Christopher M. Tan, Bin Zhang, 2012, Molecular systems biology.

Genetics of gene expression and its effect on disease

H. Stefánsson, R. Fossdal, D. Gudbjartsson, 2008, Nature.

Variations in DNA elucidate molecular networks that cause disease

S. Horvath, Bin Zhang, Chunsheng Zhang, 2008, Nature.

An integrative genomics approach to infer causal associations between gene expression and disease

J. Castle, Chunsheng Zhang, J. Lamb, 2005, Nature Genetics.

Mapping the Genetic Architecture of Gene Expression in Human Liver

John D. Storey, K. Hao, A. Kasarskis, 2008, PLoS biology.

Elucidating the murine brain transcriptional network in a segregating mouse population to identify core functional modules for obesity and diabetes

J. Lamb, E. Schadt, Jun Zhu, 2006, Journal of neurochemistry.

Validation of Candidate Causal Genes for Abdominal Obesity Which Affect Shared Metabolic Pathways and Networks

Xia Yang, Eric E. Schadt, Joshua L. Deignan, 2009, Nature Genetics.

Diurnal variation of the human adipose transcriptome and the link to metabolic disease

Xia Yang, Hongyue Dai, Yudong D. He, 2009, BMC Medical Genomics.

A cell proliferation signature is a marker of extremely poor outcome in a subpopulation of breast cancer patients.

Yudong D. He, R. Stoughton, S. Friend, 2005, Cancer research.

Genetics of gene expression surveyed in maize, mouse and man

R. Stoughton, S. Friend, J. Lamb, 2003, Nature.

microRNA-122 as a regulator of mitochondrial metabolic gene network in hepatocellular carcinoma

Angela M. Liu, P. Sham, L. Lim, 2010, Molecular systems biology.

It's in Our Blood: A Glimpse of Personalized Medicine.

J. Lamb, V. Gudnason, V. Emilsson, 2020, Trends in molecular medicine.

Diet induction of monocyte chemoattractant protein-1 and its impact on obesity.

Chunsheng Zhang, J. Lamb, H. Dai, 2005, Obesity research.

Heart failure risk is accurately predicted by certain serum proteins

J. Lamb, V. Emilsson, T. Aspelund, 2022, medRxiv.

A proteogenomic signature of age-related macular degeneration in blood

J. Lamb, V. Gudnason, V. Emilsson, 2021, Nature Communications.

Integrating genotypic and expression data in a segregating mouse population to identify 5-lipoxygenase as a susceptibility gene for obesity and bone traits

E E Schadt, J. Lamb, E. Schadt, 2005, Nature Genetics.

An integrative genomics approach to the reconstruction of gene networks in segregating populations

J. Zhu, J. Thompson, J. Lamb, 2004, Cytogenetic and Genome Research.

A genome-wide association study of serum proteins reveals shared loci with common diseases

J. Lamb, V. Gudnason, V. Emilsson, 2022, Nature Communications.

A genome-wide association study of serum proteins reveals shared loci with common diseases

J. Lamb, V. Gudnason, V. Emilsson, 2021, bioRxiv.

A survey of cancer cell lines reveals highly structured and hierarchical relationships within and between DNA and mRNA that may be the result of selection.

C. Roberts, Chunsheng Zhang, J. Lamb, 2010, Omics : a journal of integrative biology.

Title MicroRNA-122 as a regulator of mitochondrial metabolic genenetwork in hepatocellular carcinoma

Angela M. Liu, P. Sham, L. Lim, 2010 .

Co-regulatory networks of human serum proteins link genetics to disease

Xia Yang, Le Shu, Vilmundur Gudnason, 2018, Science.

Coding and regulatory variants are associated with serum protein levels and disease

James R. Staley, J. Lamb, V. Gudnason, 2022, Nature communications.

Circulating Protein Signatures and Causal Candidates for Type 2 Diabetes

J. Lamb, V. Gudnason, V. Emilsson, 2020, Diabetes.

A Comprehensive Characterization of Genome-Wide Copy Number Aberrations in Colorectal Cancer Reveals Novel Oncogenes and Patterns of Alterations

J. Lamb, J. Hodgson, M. Delorenzi, 2012, PloS one.

Correlation set analysis: detecting active regulators in disease populations using prior causal knowledge

C. DeLisi, J. Lamb, L. Chindelevitch, 2012, BMC Bioinformatics.

Coding and regulatory variants are associated with serum protein levels and disease

James R. Staley, J. Lamb, V. Gudnason, 2022, Nature Communications.

Coding and regulatory variants affect serum protein levels and common disease

James R. Staley, J. Lamb, V. Gudnason, 2020, bioRxiv.

The C3a Anaphylatoxin Receptor Is a Key Mediator of Insulin Resistance and Functions by Modulating Adipose Tissue Macrophage Infiltration and Activation

J. Lamb, E. Schadt, B. Kennedy, 2009, Diabetes.

Identification of biomarkers for tumor endothelial cell proliferation through gene expression profiling

Robert L. Phillips, Chunsheng Zhang, J. Lamb, 2005, Molecular Cancer Therapeutics.

Inferring causal genomic alterations in breast cancer using gene expression data

Tao Xie, Jun Zhu, Zhan Zhang, 2011, BMC Systems Biology.

Common dysregulation network in the human prefrontal cortex underlies two neurodegenerative diseases

Xia Yang, Guoping Fan, Eric E Schadt, 2014 .

Predictive Genes in Adjacent Normal Tissue Are Preferentially Altered by sCNV during Tumorigenesis in Liver Cancer and May Rate Limiting

Justin Guinney, Hongyue Dai, Eric E. Schadt, 2011, PloS one.

Human serum proteome profoundly overlaps with genetic signatures of disease

James R. Staley, J. Lamb, V. Gudnason, 2020 .

The effect of food intake on gene expression in human peripheral blood

Eric E. Schadt, Jun Zhu, John R. Lamb, 2009, Human molecular genetics.

Predicting prognosis in hepatocellular carcinoma after curative surgery with common clinicopathologic parameters

P. Sham, Chunsheng Zhang, J. Lamb, 2009, BMC Cancer.

Clinicopathologic and gene expression parameters predict liver cancer prognosis

P. Sham, Bin Zhang, Chunsheng Zhang, 2011, BMC Cancer.

Deep serum proteomics reveal biomarkers and causal candidates for type 2 diabetes

J. Lamb, V. Gudnason, V. Emilsson, 2019, bioRxiv.

ACE2 levels are altered in comorbidities linked to severe outcome in COVID-19

J. Lamb, V. Gudnason, V. Emilsson, 2020, medRxiv.

Serum levels of ACE2 are higher in patients with obesity and diabetes

J. Lamb, V. Gudnason, V. Emilsson, 2020, Obesity science & practice.

Characterizing Dynamic Changes in the Human Blood Transcriptional Network

Kai Wang, Jun Zhu, Eric E. Schadt, 2010, PLoS Comput. Biol..

Integrating genotypic and expression data in a segregating mouse population to identify 5-lipoxygenase as a susceptibility gene for obesity and bone traits

Eric E. Schadt, Aldons J. Lusis, Pek Yee Lum, 2005 .

Systems analysis of eleven rodent disease models reveals an inflammatome signature and key drivers

Christopher M. Tan, Bin Zhang, Chunsheng Zhang, 2012, Molecular systems biology.

Diurnal variation of the human adipose transcriptome and the link to metabolic disease

Chunsheng Zhang, J. Lamb, E. Schadt, 2009 .

Common dysregulation network in the human prefrontal cortex underlies two neurodegenerative diseases

Andrew D. Johnson, Bin Zhang, J. McElwee, 2014 .

Title Clinicopathologic and gene expression parameters predict livercancer prognosis

Bin Zhang, Chunsheng Zhang, J. Lamb, 2011 .

Molecular Systems Biology Peer Review Process File Systems Analysis of Eleven Rodent Disease Models Reveals an Inflammatome Signature and Key Drivers Transaction Report

Christopher M. Tan, Bin Zhang, Chunsheng Zhang, 2022 .

Diurnal variation of the human adipose transcriptome and the link to metabolic disease

Chunsheng Zhang, J. Lamb, E. Schadt, 2009, BMC Medical Genomics.

Correlation set analysis: detecting active regulators in disease populations using prior causal knowledge

Chia-Ling Huang, Charles DeLisi, Justin Guinney, 2012, BMC Bioinformatics.

Molecular Systems Biology Peer Review Process File Common Dysregulation Network in the Human Prefrontal Cortex Underlies Two Neurodegenerative Diseases Transaction Report

Andrew D. Johnson, Bin Zhang, J. McElwee, 2022 .