D. Stone

发表

Integrated Systems Approach Identifies Genetic Nodes and Networks in Late-Onset Alzheimer’s Disease

L. Tran, Bin Zhang, C. Gaiteri, 2013, Cell.

Transcriptional Architecture of the Primate Neocortex

Allan R. Jones, Ed S. Lein, Daniel H. Geschwind, 2012, Neuron.

Prediction of clinical drug efficacy by classification of drug-induced genomic expression profiles in vitro

D. Stone, M. Heyes, E. Gunther, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Systems biology approach for new target and biomarker identification.

I-Ming Wang, D. Stone, D. Nickle, 2013, Current topics in microbiology and immunology.

Evidence for novel susceptibility genes for late-onset Alzheimer's disease from a genome-wide association study of putative functional variants.

M. Gill, M. Owen, R. Segurado, 2007, Human molecular genetics.

Species specific exome probes reveal new insights in positively selected genes in nonhuman primates

C. Molony, D. Stone, Xiao Liu, 2016, Scientific Reports.

Pathogenic Huntingtin Repeat Expansions in Patients with Frontotemporal Dementia and Amyotrophic Lateral Sclerosis

Timothy A. Miller, Jennifer E. Phillips-Cremins, Lilah M. Besser, 2020, Neuron.

Genome sequencing analysis identifies new loci associated with Lewy body dementia and provides insights into the complex genetic architecture

Sonja W. Scholz, Lilah M. Besser, Alan J. Thomas, 2020, bioRxiv.

Inhibition of Calcineurin-mediated Endocytosis and α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptors Prevents Amyloid β Oligomer-induced Synaptic Disruption

Xiaohua Douglas Zhang, M. Ferrer, D. Stone, 2009, The Journal of Biological Chemistry.

Shared polygenic risk and causal inferences in amyotrophic lateral sclerosis

Sonja W. Scholz, Hannah A. Pliner, John D. Eicher, 2019, Annals of neurology.

TMEM175 deficiency impairs lysosomal and mitochondrial function and increases α-synuclein aggregation

Dawn M. Toolan, D. Stone, J. Disa, 2017, Proceedings of the National Academy of Sciences.

Comparative transcriptomics of choroid plexus in Alzheimer’s disease, frontotemporal dementia and Huntington’s disease: implications for CSF homeostasis

Miles C. Miller, A. Podtelezhnikov, D. Stone, 2018, Fluids and Barriers of the CNS.

Association of Variants in the SPTLC1 Gene With Juvenile Amyotrophic Lateral Sclerosis

Sonja W. Scholz, Hannah A. Pliner, Janel O. Johnson, 2021, JAMA neurology.

Mutations in the SPTLC1 gene are a cause of amyotrophic lateral sclerosis that may be amenable to serine supplementation

Sonja W. Scholz, Hannah A. Pliner, Janel O. Johnson, 2019, bioRxiv.

Pathogenic Huntingtin Repeat Expansions in Patients with Frontotemporal Dementia and Amyotrophic Lateral Sclerosis.

Timothy A. Miller, Sonja W. Scholz, Jennifer E. Phillips-Cremins, 2020, Neuron.

Genome-wide Analyses Identify KIF5A as a Novel ALS Gene in and for Therapeutic

Timothy A. Miller, Denis C. Bauer, Shankaracharya, 2018 .

Genome sequencing analysis identifies new loci associated with Lewy body dementia and provides insights into its genetic architecture

Sonja W. Scholz, Lilah M. Besser, Alan J. Thomas, 2021, Nature Genetics.

Investigating the genetic architecture of dementia with Lewy bodies: a two-stage genome-wide association study

Sonja W. Scholz, John D. Eicher, D. Hernandez, 2018, The Lancet Neurology.

Next-generation sequencing reveals substantial genetic contribution to dementia with Lewy bodies

Sonja W. Scholz, D. Hernandez, A. Singleton, 2016, Neurobiology of Disease.

Heritability and genetic variance of dementia with Lewy bodies

Sonja W. Scholz, John D. Eicher, D. Hernandez, 2018, Neurobiology of Disease.

Molecular Profiling of a 6-Hydroxydopamine Model of Parkinson’s Disease

D. Stone, A. Dilella, J. Hess, 2010, Neurochemical Research.

Molecular Insights into the Pathogenesis of Alzheimer's Disease and Its Relationship to Normal Aging

A. Podtelezhnikov, D. Stone, Andrey Loboda, 2011, PloS one.

Common dysregulation network in the human prefrontal cortex underlies two neurodegenerative diseases

Xia Yang, Guoping Fan, Eric E Schadt, 2014 .

Correction: Pathway-Based Analysis of Genome-Wide siRNA Screens Reveals the Regulatory Landscape of App Processing

Shane D. Marine, K. Mizuguchi, Xiaohua Douglas Zhang, 2015, PloS one.

Pathway-Based Analysis of Genome-Wide siRNA Screens Reveals the Regulatory Landscape of App Processing

Paolo Uva, Kenji Mizuguchi, Marc Ferrer, 2015, PloS one.

Investigating the genetic architecture of Dementia with Lewy bodies: a genome-wide association study

Sonja W. Scholz, D. Hernandez, A. Singleton, 2018 .

Refined anatomical isolation of functional sleep circuits exhibits distinctive regional and circadian gene transcriptional profiles

Kenneth S. Koblan, John J. Renger, M. Marton, 2009, Brain Research.

Blood-gene expression reveals reduced circadian rhythmicity in individuals resistant to sleep deprivation.

A. Podtelezhnikov, D. Stone, A. Pack, 2014, Sleep.

LRRTM3 promotes processing of amyloid-precursor protein by BACE1 and is a positional candidate gene for late-onset Alzheimer's disease

Shane D. Marine, Amy S. Espeseth, Min Xu, 2006, Proceedings of the National Academy of Sciences.

A genome wide analysis of ubiquitin ligases in APP processing identifies a novel regulator of BACE1 mRNA levels

Min Xu, Xiao-Ping Shi, Yuanjiang Yu, 2006, Molecular and Cellular Neuroscience.

A comprehensive screening of copy number variability in dementia with Lewy bodies

Sonja W. Scholz, John D. Eicher, D. Hernandez, 2019, Neurobiology of Aging.

ApoE genotyping as a progression-rate biomarker in phase II disease-modification trials for Alzheimer's disease

C. Suver, C. Molony, D. Stone, 2010, The Pharmacogenomics Journal.

Transcriptional Profiling of Cholinergic Neurons From Basal Forebrain Identifies Changes in Expression of Genes Between Sleep and Wake

A. Podtelezhnikov, D. Stone, A. Pack, 2017, Sleep.

Melatonin receptor type 1A gene linked to Alzheimer’s disease in old age

T. Paunio, D. Stone, T. Peuralinna, 2018, Sleep.

Functionalization of the TMEM175 p.M393T variant as a risk factor for Parkinson disease

Dawn M. Toolan, M. Nalls, A. Singleton, 2019, Human molecular genetics.

High-Throughput Screening by RNA Interference: Control of Two Distinct Types of Variance

Shane D. Marine, Amy S. Espeseth, M. Ferrer, 2007, Cell cycle.

Diagnosis of Parkinson's disease on the basis of clinical and genetic classification: a population-based modelling study

Margaret Sutherland, John P A Ioannidis, Daniel Weintraub, 2015, The Lancet Neurology.

Analysis of neurodegenerative disease-causing genes in dementia with Lewy bodies

D. Hernandez, A. Singleton, J. Morris, 2020, Acta Neuropathologica Communications.

Enhancing the Function of CD34+ Cells by Targeting Plasminogen Activator Inhibitor-1

D. Stone, M. Boulton, C. Pepine, 2013, PloS one.

Alzheimer risk loci and associated neuropathology in a population-based study (Vantaa 85+)

A. Singleton, A. Paetau, D. Stone, 2018, Neurology: Genetics.

Baseline genetic associations in the Parkinson's Progression Markers Initiative (PPMI)

D. Hernandez, M. Nalls, A. Singleton, 2016, Movement disorders : official journal of the Movement Disorder Society.

Genetic variability and potential effects on clinical trial outcomes: perspectives in Parkinson’s disease

M. Nalls, A. Singleton, H. Leonard, 2018, Journal of Medical Genetics.

Transcriptional responses to loss or gain of function of the leucine-rich repeat kinase 2 (LRRK2) gene uncover biological processes modulated by LRRK2 activity.

D. Stone, T. Dawson, V. Dawson, 2012, Human molecular genetics.

Oligogenic basis of sporadic ALS

A. Paetau, D. Stone, J. Schleutker, 2019, Neurology: Genetics.

Genome-wide structural variant analysis identifies risk loci for non-Alzheimer’s dementias

Ryan L. Collins, Sonja W. Scholz, Toshiko Tanaka, 2023, Cell genomics.

Alterations in choroid plexus gene expression in Alzheimer’s disease provide inferences for CSF composition and dynamics

Miles C. Miller, A. Podtelezhnikov, D. Stone, 2010, Cerebrospinal Fluid Research.

Parkinson disease among patients treated for benign prostatic hyperplasia with α1 adrenergic receptor antagonists.

D. Stone, J. Renger, S. Duvvuri, 2021, The Journal of clinical investigation.

Identification of a sex-specific genetic signature in dementia with Lewy bodies: a meta-analysis of genome-wide association studies

John X. Morris, Elisabet, Sonja W. Scholz, 2022, medRxiv.

Melatonin receptor type 1A gene linked to Alzheimer’s disease in old age

Traynor, T. Paunio, D. Stone, 2018, Sleep.

A quantitative genomic expression analysis platform for multiplexed in vitro prediction of drug action

J. Rothberg, D. Stone, R. Gerwien, 2005, The Pharmacogenomics Journal.

Common dysregulation network in the human prefrontal cortex underlies two neurodegenerative diseases

Andrew D. Johnson, Bin Zhang, J. McElwee, 2014 .

A Comparative Study on the Lysosomal Cation Channel TMEM175 Using Automated Whole-Cell Patch-Clamp, Lysosomal Patch-Clamp, and Solid Supported Membrane-Based Electrophysiology: Functional Characterization and High-Throughput Screening Assay Development

D. Stone, J. Renger, N. Fertig, 2023, International journal of molecular sciences.

Activity profile-based siRNA screen to explore the functional genomics of Alzheimer's disease

Shane D. Marine, Amy S. Espeseth, Min Xu, 2007 .

Analysis of C9orf72 repeat expansions in a large international cohort of dementia with Lewy bodies

D. Hernandez, D. Stone, R. Petersen, 2017, Neurobiology of Aging.

Molecular Systems Biology Peer Review Process File Common Dysregulation Network in the Human Prefrontal Cortex Underlies Two Neurodegenerative Diseases Transaction Report

Andrew D. Johnson, Bin Zhang, J. McElwee, 2022 .