I. Gulcin

发表

Purification and Characterization of Peroxidase from Sweet Gourd (Cucurbita moschata Lam. Poiret)

Ekrem Koksal, E. Bursal, A. G. Aggul, 2012 .

Novel amine-functionalized benzimidazolium salts: Synthesis, characterization, bioactivity, and molecular docking studies

I. Gulcin, Murat Yiğit, B. Yiǧit, 2020 .

Antidiabetic potential: in vitro inhibition effects of some natural phenolic compounds on α‐glycosidase and α‐amylase enzymes

I. Gulcin, P. Taslimi, Parham Taslimi, 2017, Journal of biochemical and molecular toxicology.

Synthesis of 4,5-disubstituted-2-thioxo-1,2,3,4-tetrahydropyrimidines and investigation of their acetylcholinesterase, butyrylcholinesterase, carbonic anhydrase I/II inhibitory and antioxidant activities

I. Gulcin, C. Supuran, P. Taslimi, 2016, Journal of enzyme inhibition and medicinal chemistry.

Metal Ions, Metal Chelators and Metal Chelating Assay as Antioxidant Method

I. Gulcin, S. Alwasel, 2022, Processes.

LC-HRMS Profiling and Antidiabetic, Anticholinergic, and Antioxidant Activities of Aerial Parts of Kınkor (Ferulago stellata)

I. Gulcin, S. Alwasel, Fevzi Topal, 2021, Molecules.

Evaluation of the Antioxidant and Antiradical Properties of Some Phyto and Mammalian Lignans

I. Gulcin, Leyla Polat Kose, 2021, Molecules.

In vitro effects of standard antioxidants on lactoperoxidase enzyme–A molecular docking approach

I. Gulcin, M. Karaman, Pınar Kalın, 2019, Journal of biochemical and molecular toxicology.

Anticholinergic, antidiabetic and antioxidant activities of cinnamon (cinnamomum verum) bark extracts: polyphenol contents analysis by LC-MS/MS

I. Gulcin, S. Alwasel, M. Topal, 2019, International Journal of Food Properties.

Synthesis, characterization, antioxidant, antidiabetic, anticholinergic, and antiepileptic properties of novel N‐substituted tetrahydropyrimidines based on phenylthiourea

I. Gulcin, P. Taslimi, Lokman Durmaz, 2018, Journal of biochemical and molecular toxicology.

Acetylcholinesterase Inhibitory and Antioxidant Activities of Novel Symmetric Sulfamides Derived from Phenethylamines

I. Gulcin, Fevzi Topal, F. Tümer, 2015, Archiv der Pharmazie.

Capsaicin: A Potent Inhibitor of Carbonic Anhydrase Isoenzymes

I. Gulcin, S. Alwasel, Betul Arabaci, 2014, Molecules.

Screening of Carbonic Anhydrase, Acetylcholinesterase, Butyrylcholinesterase, and α-Glycosidase Enzyme Inhibition Effects and Antioxidant Activity of Coumestrol

I. Gulcin, S. Alwasel, Lokman Durmaz, 2022, Molecules.

Oleuropein and Verbascoside - Their Inhibition Effects on Carbonic Anhydrase and Molecular Docking Studies.

A. G. Aggul, I. Gulcin, P. Taslimi, 2021, Journal of oleo science.

Aminoalkylated Phenolic Chalcones: Investigation of Biological Effects on Acetylcholinesterase and Carbonic Anhydrase I and II as Potential Lead Enzyme Inhibitors

I. Gulcin, C. Yamali, H. Gul, 2020 .

Concise syntheses and some biological activities of dl‐2,5‐di‐O‐methyl‐chiro‐inositol, dl‐1,4‐di‐O‐methyl‐scyllo‐inositol, and dl‐1,6‐dibromo‐1,6‐dideoxy‐2,5‐di‐O‐methyl‐chiro‐inositol

I. Gulcin, Hulya Akıncıoğlu, Kadir Aksu, 2020, Archiv der Pharmazie.

An Important Milk Enzyme :

I. Gulcin, H. Ozdemir, Zeynep Koksal, 2018 .

Cytotoxic effects, carbonic anhydrase isoenzymes, α-glycosidase and acetylcholinesterase inhibitory properties, and molecular docking studies of heteroatom-containing sulfonyl hydrazone derivatives

I. Gulcin, P. Taslimi, Yavuz Erden, 2020, Journal of biomolecular structure & dynamics.

The impact of some natural phenolic compounds on carbonic anhydrase, acetylcholinesterase, butyrylcholinesterase, and α‐glycosidase enzymes: An antidiabetic, anticholinergic, and antiepileptic study

I. Gulcin, P. Taslimi, C. Caglayan, 2017, Journal of biochemical and molecular toxicology.

Trace elements and some extracellular antioxidant protein levels in serum of patients with laryngeal cancer

I. Gulcin, F. Akçay, S. Taysı, 2007, Biological Trace Element Research.

Synthesis of some tetrahydropyrimidine-5-carboxylates, determination of their metal chelating effects and inhibition profiles against acetylcholinesterase, butyrylcholinesterase and carbonic anhydrase

I. Gulcin, C. Supuran, P. Taslimi, 2016, Journal of enzyme inhibition and medicinal chemistry.

Antioxidant activity of an anatolian herbal tea—Origanum minutiflorum: isolation and characterization of its secondary metabolites

I. Gulcin, R. Erenler, M. Elmastaș, 2018 .

The antidiabetic and anticholinergic effects of chrysin on cyclophosphamide‐induced multiple organ toxicity in rats: Pharmacological evaluation of some metabolic enzyme activities

I. Gulcin, P. Taslimi, Yeliz Demir, 2019, Journal of biochemical and molecular toxicology.

Synthesis, characterization and biological evaluation ofN‐substituted triazinane‐2‐thiones and theoretical–experimental mechanism of condensation reaction

I. Gulcin, P. Taslimi, Ruya Kaya, 2020 .

Synthesis, crystal structure and biological evaluation of spectroscopic characterization of Ni(II) and Co(II) complexes with N‐salicyloil‐N′‐maleoil‐hydrazine as anticholinergic and antidiabetic agents

I. Gulcin, P. Taslimi, O. Şahin, 2018, Journal of biochemical and molecular toxicology.

Synthesis and discovery of potent carbonic anhydrase, acetylcholinesterase, butyrylcholinesterase, and α‐glycosidase enzymes inhibitors: The novel N,N′‐bis‐cyanomethylamine and alkoxymethylamine derivatives

I. Gulcin, P. Taslimi, Ruya Kaya, 2018, Journal of biochemical and molecular toxicology.

Antioxidant, Antidiabetic, Anticholinergic, and Antiglaucoma Effects of Magnofluorine

I. Gulcin, S. Alwasel, Lokman Durmaz, 2022, Molecules.

Synthesis, Characterization, Molecular Docking, Acetylcholinesterase and α‐Glycosidase Inhibition Profiles of Nitrogen‐Based Novel Heterocyclic Compounds

I. Gulcin, N. Gusarova, S. Malysheva, 2022, ChemistrySelect.

Synthesis, characterization, biological evaluation, and molecular docking studies of some piperonyl‐based 4‐thiazolidinone derivatives

I. Gulcin, P. Taslimi, B. Tuzun, 2019, Archiv der Pharmazie.

Inhibition profile of a series of phenolic acids on bovine lactoperoxidase enzyme

I. Gulcin, M. Çankaya, H. Ozdemir, 2015, Journal of enzyme inhibition and medicinal chemistry.

Synthesis and antioxidant activities of phenol derivatives from 1,6-bis(dimethoxyphenyl)hexane-1,6-dione.

I. Gulcin, P. Taslimi, E. Şahin, 2020, Bioorganic chemistry.

Preliminary phytochemical analysis and evaluation of in vitro antioxidant, antiproliferative, antidiabetic, and anticholinergics effects of endemic Gypsophila taxa from Turkey.

Ekrem Koksal, I. Gulcin, A. Altay, 2019, Journal of food biochemistry.

Synthesis and investigation of the conversion reactions of pyrimidine‐thiones with nucleophilic reagent and evaluation of their acetylcholinesterase, carbonic anhydrase inhibition, and antioxidant activities

I. Gulcin, P. Taslimi, É. Garibov, 2018, Journal of biochemical and molecular toxicology.

Synthesis of some novel pyridine compounds containing bis‐1,2,4‐triazole/thiosemicarbazide moiety and investigation of their antioxidant properties, carbonic anhydrase, and acetylcholinesterase enzymes inhibition profiles

I. Gulcin, A. Çetin, P. Taslimi, 2018, Journal of biochemical and molecular toxicology.

An analysis of expression patterns of genes encoding proteins with catalytic activities

G. Eichele, I. Gulcin, A. Hernandez, 2007, BMC Genomics.

human monoamine oxidase (hMAO) A and hMAO B inhibitors from Artemisia dracunculus L. herniarin and skimmin: human mononamine oxidase A and B inhibitors from A. dracunculus L.

I. Gulcin, Hulya Akıncıoğlu, Mehmet Gumustas, 2020, Zeitschrift fur Naturforschung. C, Journal of biosciences.

The Impacts of Some Sedative Drugs on α -Glycosidase, Acetylcholinesterase and Butyrylcholinesterase Enzymes-potential Drugs for Some Metabolic Diseases

I. Gulcin, P. Taslimi, I. Gülçin, 2019, Letters in Drug Design & Discovery.

Synthesis and Enzyme Inhibitory Properties of Quinoxaline Bridged Bis(imidazolium) Salts

I. Gulcin, Murat Yiğit, B. Yiǧit, 2022, HETEROCYCLES.

Novel quinazolin–sulfonamid derivatives: synthesis, characterization, biological evaluation, and molecular docking studies

I. Gulcin, B. Larijani, P. Taslimi, 2020, Journal of biomolecular structure & dynamics.

Design, synthesis, characterization, biological evaluation, and molecular docking studies of novel 1,2-aminopropanthiols substituted derivatives as selective carbonic anhydrase, acetylcholinesterase and α-glycosidase enzymes inhibitors

I. Gulcin, P. Taslimi, S. Alwasel, 2020, Journal of biomolecular structure & dynamics.

Synthesis, characterization, molecular docking, and biological activities of coumarin–1,2,3‐triazole‐acetamide hybrid derivatives

I. Gulcin, B. Larijani, P. Taslimi, 2020, Archiv der Pharmazie.

Synthesis, cytotoxic, and carbonic anhydrase inhibitory effects of new 2‐(3‐(4‐methoxyphenyl)‐5‐(aryl)‐4,5‐dihydro‐1H‐pyrazol‐1‐yl)benzo[d]thiazole derivatives

I. Gulcin, H. Sakagami, H. Gul, 2020 .

Screening of non-alkaloid acetylcholinesterase and carbonic anhydrase isoenzymes inhibitors of Leiotulus dasyanthus (K. Koch) Pimenov & Ostr. (Apiaceae)

I. Gulcin, B. Demirci, M. Koca, 2020 .

Identification of non-alkaloid natural compounds of Angelica purpurascens (Avé-Lall.) Gilli. (Apiaceae) with cholinesterase and carbonic anhydrase inhibition potential

I. Gulcin, O. Sytar, M. Brestič, 2019, Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society.

SAR Evaluation of Disubstituted Tacrine Analogues as Promising Cholinesterase and Carbonic Anhydrase Inhibitors

I. Gulcin, A. Tutar, G. Topçu, 2019, Indian Journal of Pharmaceutical Education and Research.

Aminopyrazole‐substituted metallophthalocyanines: Preparation, aggregation behavior, and investigation of metabolic enzymes inhibition properties

I. Gulcin, P. Taslimi, M. Nebioğlu, 2019, Archiv der Pharmazie.

Synthesis and characterization of novel substituted thiophene derivatives and discovery of their carbonic anhydrase and acetylcholinesterase inhibition effects

I. Gulcin, P. Taslimi, A. Cetin, 2018, Journal of biochemical and molecular toxicology.

New azafluorenones with cytotoxic and carbonic anhydrase inhibitory properties: 2-Aryl-4-(4-hydroxyphenyl)-5H-indeno[1,2-b]pyridin-5-ones.

I. Gulcin, C. Supuran, H. Sakagami, 2018, Bioorganic chemistry.

Novel thymol bearing oxypropanolamine derivatives as potent some metabolic enzyme inhibitors - Their antidiabetic, anticholinergic and antibacterial potentials.

I. Gulcin, P. Taslimi, O. Karabay, 2018, Bioorganic chemistry.

Antidiabetic potential: In vitro inhibition effects of bromophenol and diarylmethanones derivatives on metabolic enzymes

I. Gulcin, P. Taslimi, Yeliz Demir, 2018, Archiv der Pharmazie.

Some pyrazoles derivatives: Potent carbonic anhydrase, α‐glycosidase, and cholinesterase enzymes inhibitors

I. Gulcin, P. Taslimi, A. Cetin, 2018, Archiv der Pharmazie.

Novel amides of 1,1‐bis‐(carboxymethylthio)‐1‐arylethanes: Synthesis, characterization, acetylcholinesterase, butyrylcholinesterase, and carbonic anhydrase inhibitory properties

I. Gulcin, P. Taslimi, A. Sujayev, 2018, Journal of biochemical and molecular toxicology.

Novel N‐propylphthalimide‐ and 4‐vinylbenzyl‐substituted benzimidazole salts: Synthesis, characterization, and determination of their metal chelating effects and inhibition profiles against acetylcholinesterase and carbonic anhydrase enzymes

I. Gulcin, P. Taslimi, Y. Sarı, 2018, Journal of biochemical and molecular toxicology.

Evaluation of acetylcholinesterase and carbonic anhydrase inhibition profiles of 1,2,3,4,6‐pentasubstituted‐4‐hydroxy‐cyclohexanes

I. Gulcin, P. Taslimi, Hayreddin Gezegen, 2017, Journal of biochemical and molecular toxicology.

Discovery of potent carbonic anhydrase, acetylcholinesterase, and butyrylcholinesterase enzymes inhibitors: The new amides and thiazolidine‐4‐ones synthesized on an acetophenone base

I. Gulcin, P. Taslimi, S. Alwasel, 2017, Journal of biochemical and molecular toxicology.

Microwave-assisted synthesis and bioevaluation of new sulfonamides

I. Gulcin, C. Supuran, C. Yamali, 2017, Journal of enzyme inhibition and medicinal chemistry.

Novel eugenol derivatives: Potent acetylcholinesterase and carbonic anhydrase inhibitors.

I. Gulcin, Fevzi Topal, A. Daştan, 2017, International journal of biological macromolecules.

Synthesis and Carbonic Anhydrase Inhibition of Novel 2‐(4‐(Aryl)thiazole‐2‐yl)‐3a,4,7,7a‐tetrahydro‐1H‐4,7‐methanoisoindole‐1,3(2H)‐dione Derivatives

I. Gulcin, M. Ceylan, Y. Temel, 2016, Archiv der Pharmazie.

Synthesis, cytotoxicity and carbonic anhydrase inhibitory activities of new pyrazolines

I. Gulcin, C. Supuran, C. Yamali, 2016, Journal of enzyme inhibition and medicinal chemistry.

Synthesis and carbonic anhydrase inhibitory activities of new thienyl-substituted pyrazoline benzenesulfonamides

I. Gulcin, C. Supuran, H. Inci Gul, 2016, Journal of enzyme inhibition and medicinal chemistry.

Inhibitory effects of isatin Mannich bases on carbonic anhydrases, acetylcholinesterase, and butyrylcholinesterase

I. Gulcin, C. Supuran, C. Yamali, 2016, Journal of enzyme inhibition and medicinal chemistry.

One-step purification of lactoperoxidase from bovine milk by affinity chromatography.

I. Gulcin, I. Gülçin, H. Özdemir, 2013, Food chemistry.

Comprehensive metabolic profiling of Acantholimon caryophyllaceum using LC–HRMS and evaluation of antioxidant activities, enzyme inhibition properties and molecular docking studies

I. Gulcin, S. Alwasel, A. Goren, 2022, South African Journal of Botany.

A Novel Ag-N-Heterocyclic Carbene Complex Bearing the Hydroxyethyl Ligand: Synthesis, Characterization, Crystal and Spectral Structures and Bioactivity Properties

I. Gulcin, P. Taslimi, Hulya Akıncıoğlu, 2020, Crystals.

Metal contained Phthalocyanines with 3,4-Dimethoxyphenethoxy substituents: their anticancer, antibacterial activities and their inhibitory effects on some metabolic enzymes with molecular docking studies

I. Gulcin, P. Taslimi, F. Türkan, 2020, Journal of biomolecular structure & dynamics.

In vitro cytotoxic and in vivo antitumoral activities of some aminomethyl derivatives of 2,4‐dihydro‐3H‐1,2,4‐triazole‐3‐thiones—Evaluation of their acetylcholinesterase and carbonic anhydrase enzymes inhibition profiles

I. Gulcin, P. Taslimi, M. Karatepe, 2018, Journal of biochemical and molecular toxicology.

Inhibitory effects of oxytocin and oxytocin receptor antagonist atosiban on the activities of carbonic anhydrase and acetylcholinesterase enzymes in the liver and kidney tissues of rats

I. Gulcin, P. Taslimi, A. Taskiran, 2017, Journal of biochemical and molecular toxicology.

Novel carvacrol based new oxypropanolamine derivatives: Design, synthesis, characterization, biological evaluation, and molecular docking studies

I. Gulcin, P. Taslimi, M. Zengin, 2020 .

Antioxidants and antioxidant methods: an updated overview

I. Gulcin, 2020, Archives of Toxicology.

2 H ‐Indazolo [2,1‐ b ]phthalazine‐trione derivatives: Inhibition on some metabolic enzymes and molecular docking studies

I. Gulcin, P. Taslimi, Halide S Karaman, 2020 .

Investigation of inhibitory properties of some hydrazone compounds on hCA I, hCA II and AChE enzymes.

I. Gulcin, C. Supuran, P. Taslimi, 2019, Bioorganic chemistry.

Novel tribenzylaminobenzolsulphonylimine based on their pyrazine and pyridazines: Synthesis, characterization, antidiabetic, anticancer, anticholinergic, and molecular docking studies.

I. Gulcin, P. Taslimi, S. Alwasel, 2019, Bioorganic chemistry.

Antioxidant and Radical Scavenging Activity of Aerial Parts and Roots of Turkish Liquorice (Glycyrrhiza Glabra L.)

I. Gulcin, Hatice Tohma, 2010 .

Comprehensive Metabolite Profiling of Cinnamon (Cinnamomum zeylanicum) Leaf Oil Using LC-HR/MS, GC/MS, and GC-FID: Determination of Antiglaucoma, Antioxidant, Anticholinergic, and Antidiabetic Profiles

I. Gulcin, S. Alwasel, Ekrem Köksal, 2023, Life.

Metal chelating and hydrogen peroxide scavenging effects of melatonin

I. Gulcin, M. Buyukokuroglu, O. I. Kufrevioglu, 2003, Journal of pineal research.

On the in vitro antioxidative properties of melatonin

I. Gulcin, M. Oktay, M. Buyukokuroglu, 2002, Journal of pineal research.

Synthesis and bioactivity of several new hetaryl sulfonamides

I. Gulcin, P. Taslimi, S. Alwasel, 2017, Journal of enzyme inhibition and medicinal chemistry.

The synthesis of some β-lactams and investigation of their metal-chelating activity, carbonic anhydrase and acetylcholinesterase inhibition profiles

I. Gulcin, C. Supuran, P. Taslimi, 2016, Journal of enzyme inhibition and medicinal chemistry.

Antioxidants and antioxidant methods: an updated overview

I. Gulcin, 2020, Archives of Toxicology.

Synthesis, crystal structure, and biological evaluation of optically active 2‐amino‐4‐aryl‐7,7‐dimethyl‐5‐oxo‐5,6,7,8‐tetrahydro‐4H‐chromen‐3‐carbonitriles: Antiepileptic, antidiabetic, and anticholinergics potentials

I. Gulcin, P. Taslimi, A. Maharramov, 2019, Archiv der Pharmazie.

Novel benzo[b]xanthene derivatives: Bismuth(III) triflate-catalyzed one-pot synthesis, characterization, and acetylcholinesterase, glutathione S-transferase, and butyrylcholinesterase inhibitory properties.

I. Gulcin, P. Taslimi, Halide S Karaman, 2020, Archiv der Pharmazie.

Synthesis, molecular modeling, and biological evaluation of 4‐[5‐aryl‐3‐(thiophen‐2‐yl)‐4,5‐dihydro‐1H‐pyrazol‐1‐yl] benzenesulfonamides toward acetylcholinesterase, carbonic anhydrase I and II enzymes

I. Gulcin, C. Yamali, P. Taslimi, 2018, Chemical biology & drug design.

Synthesis, carbonic anhydrase I and II inhibition studies of the 1,3,5-trisubstituted-pyrazolines

I. Gulcin, C. Supuran, P. Taslimi, 2016, Journal of enzyme inhibition and medicinal chemistry.

A class of sulfonamides as carbonic anhydrase I and II inhibitors

I. Gulcin, T. Ozturk, A. Goren, 2016, Journal of enzyme inhibition and medicinal chemistry.

Probing 4-(diethylamino)-salicylaldehyde-based thiosemicarbazones as multi-target directed ligands against cholinesterases, carbonic anhydrases and α-glycosidase enzymes.

I. Gulcin, P. Taslimi, H. Mohamad, 2020, Bioorganic chemistry.

Synthesis of new cyclic thioureas and evaluation of their metal‐chelating activity, acetylcholinesterase, butyrylcholinesterase, and carbonic anhydrase inhibition profiles

I. Gulcin, P. Taslimi, S. Alwasel, 2017, Journal of biochemical and molecular toxicology.

N‐Substituted pyrimidinethione and acetophenone derivatives as a new therapeutic approach in diabetes

I. Gulcin, P. Taslimi, M. Karaman, 2020, Archiv der Pharmazie.

Synthesis and bioactivity studies on new 4-(3-(4-Substitutedphenyl)-3a,4-dihydro-3H-indeno[1,2-c]pyrazol-2-yl) benzenesulfonamides

I. Gulcin, C. Supuran, P. Taslimi, 2016, Journal of enzyme inhibition and medicinal chemistry.

New quinoxalin‐1,3,4‐oxadiazole derivatives: Synthesis, characterization, in vitro biological evaluations, and molecular modeling studies

I. Gulcin, B. Larijani, H. Rastegar, 2021, Archiv der Pharmazie.

Synthesis and in vitro carbonic anhydrases and acetylcholinesterase inhibitory activities of novel imidazolinone‐based benzenesulfonamides

I. Gulcin, H. Gul, Serkan Levent, 2020, Archiv der Pharmazie.

The biological activities, molecular docking studies, and anticancer effects of 1-arylsuphonylpyrazole derivatives

I. Gulcin, P. Taslimi, S. Alwasel, 2020, Journal of biomolecular structure & dynamics.

Novel functionally substituted esters based on sodium diethyldithiocarbamate derivatives: Synthesis, characterization, biological activity and molecular docking studies.

I. Gulcin, P. Taslimi, S. Alwasel, 2020, Bioorganic chemistry.

Synthesis of novel tris-chalcones and determination of their inhibition profiles against some metabolic enzymes

I. Gulcin, Ruya Kaya, Oztekin Algul, 2019, Archives of physiology and biochemistry.

Synthesis, biological evaluation and molecular docking of novel pyrazole derivatives as potent carbonic anhydrase and acetylcholinesterase inhibitors.

I. Gulcin, P. Taslimi, M. Karaman, 2019, Bioorganic chemistry.

Antidiabetic and antiparasitic potentials: Inhibition effects of some natural antioxidant compounds on α-glycosidase, α-amylase and human glutathione S-transferase enzymes.

I. Gulcin, F. Sen, P. Taslimi, 2018, International journal of biological macromolecules.

Diarylmethanon, bromophenol and diarylmethane compounds: Discovery of potent aldose reductase, α-amylase and α-glycosidase inhibitors as new therapeutic approach in diabetes and functional hyperglycemia.

I. Gulcin, P. Taslimi, Yeliz Demir, 2018, International journal of biological macromolecules.

Sulfonamide inhibitors: a patent review 2013-present

I. Gulcin, P. Taslimi, Parham Taslimi, 2018, Expert opinion on therapeutic patents.

Synthesis and biological evaluation of aminomethyl and alkoxymethyl derivatives as carbonic anhydrase, acetylcholinesterase and butyrylcholinesterase inhibitors

I. Gulcin, C. Supuran, P. Taslimi, 2017, Journal of enzyme inhibition and medicinal chemistry.

Synthesis of 4-(2-substituted hydrazinyl)benzenesulfonamides and their carbonic anhydrase inhibitory effects

I. Gulcin, C. Supuran, C. Yamali, 2016, Journal of enzyme inhibition and medicinal chemistry.

The human carbonic anhydrase isoenzymes I and II (hCA I and II) inhibition effects of trimethoxyindane derivatives

I. Gulcin, C. Supuran, P. Taslimi, 2016, Journal of enzyme inhibition and medicinal chemistry.

Design, synthesis, characterization, enzymatic inhibition evaluations, and docking study of novel quinazolinone derivatives.

I. Gulcin, B. Larijani, H. Rastegar, 2020, International journal of biological macromolecules.

Synthesis and biological evaluation of phloroglucinol derivatives possessing α‐glycosidase, acetylcholinesterase, butyrylcholinesterase, carbonic anhydrase inhibitory activity

I. Gulcin, P. Taslimi, Deryanur Kılıç, 2018, Archiv der Pharmazie.

The first synthesis, carbonic anhydrase inhibition and anticholinergic activities of some bromophenol derivatives with S including natural products.

I. Gulcin, P. Taslimi, Halide S Karaman, 2019, Bioorganic chemistry.

Imidazolinium chloride salts bearing wingtip groups: Synthesis, molecular docking and metabolic enzymes inhibition

I. Gulcin, Murat Yiğit, B. Yiǧit, 2019, Journal of Molecular Structure.

Synthesis and Carbonic Anhydrase Inhibition of Tetrabromo Chalcone Derivatives

I. Gulcin, P. Taslimi, M. Ceylan, 2017, Archiv der Pharmazie.

Synthesis and biological evaluation of novel tris-chalcones as potent carbonic anhydrase, acetylcholinesterase, butyrylcholinesterase and α-glycosidase inhibitors.

I. Gulcin, Ruya Kaya, Oztekin Algul, 2019, Bioorganic chemistry.

New phenolic Mannich bases with piperazines and their bioactivities.

I. Gulcin, C. Supuran, H. Sakagami, 2019, Bioorganic chemistry.

Highly brominated anthracenes as precursors for the convenient synthesis of 2,9,10-trisubstituted anthracene derivatives

I. Gulcin, O. Buyukgungor, O. Çakmak, 2008, Beilstein journal of organic chemistry.

Synthesis and some enzyme inhibition effects of isoxazoline and pyrazoline derivatives including benzonorbornene unit

I. Gulcin, A. Tutar, A. Menzek, 2021, Journal of biochemical and molecular toxicology.

Synthesis and biological evaluation of bromophenol derivatives with cyclopropyl moiety: Ring opening of cyclopropane with monoester.

I. Gulcin, P. Taslimi, E. Şahin, 2019, Bioorganic chemistry.

Novel 2-aminopyridine liganded Pd(II) N-heterocyclic carbene complexes: Synthesis, characterization, crystal structure and bioactivity properties.

I. Gulcin, P. Taslimi, Yeliz Demir, 2019, Bioorganic chemistry.

Novel eugenol bearing oxypropanolamines: Synthesis, characterization, antibacterial, antidiabetic, and anticholinergic potentials.

I. Gulcin, P. Taslimi, O. Karabay, 2019, Bioorganic chemistry.

Purification and characterization of the carbonic anhydrase enzyme from horse mackerel (Trachurus trachurus) muscle and the impact of some metal ions and pesticides on enzyme activity.

I. Gulcin, P. Taslimi, Yeliz Demir, 2019, Comparative biochemistry and physiology. Toxicology & pharmacology : CBP.

Antidiabetic, anticholinergic and antioxidant activities of aerial parts of shaggy bindweed (Convulvulus betonicifolia Miller subsp.) – profiling of phenolic compounds by LC-HRMS

I. Gulcin, S. Alwasel, M. Topal, 2021, Heliyon.

Antioxidant, Antimicrobial, Antifungal, and Antiradical Activities of Cyclotrichium Niveum (BOISS.) Manden and Scheng

I. Gulcin, E. Kireççi, A. Tel, 2008 .

Some phenolic natural compounds as carbonic anhydrase inhibitors: An in vitro and in silico study

A. G. Aggul, I. Gulcin, P. Taslimi, 2022, Archiv der Pharmazie.

Sahlep (Dactylorhiza osmanica): Phytochemical Analyses by LC-HRMS, Molecular Docking, Antioxidant Activity, and Enzyme Inhibition Profiles

I. Gulcin, S. Alwasel, A. Goren, 2022, Molecules.

Synthesis and bioactivities of pyrazoline benzensulfonamides as carbonic anhydrase and acetylcholinesterase inhibitors with low cytotoxicity.

I. Gulcin, C. Supuran, C. Yamali, 2019, Bioorganic chemistry.

Effects of light on trace elments and triiodothyronine levels in plasma of mirror carp (Cyprinus carpio)

I. Gulcin, T. Yanık, O. Hisar, 2007, Biological Trace Element Research.

Purification and Characterization of Polyphenol Oxidase from Hemşin Apple (Malus communis L.)

I. Gulcin, S. Alwasel, B. Aydin, 2015 .

Inhibitory effects of selected pesticides on peroxidases purified by affinity chromatography

I. Gulcin, H. Ozdemir, Ramazan Kalin, 2018 .

Lactoperoxidase inhibition of some natural phenolic compounds: Kinetics and molecular docking studies.

I. Gulcin, M. Karaman, Pınar Kalın, 2019, Journal of food biochemistry.

Synthesis and biological evaluation of some new mono Mannich bases with piperazines as possible anticancer agents and carbonic anhydrase inhibitors.

I. Gulcin, C. Supuran, K. Bandow, 2019, Bioorganic chemistry.

Synthesis and in silico studies of triazene‐substituted sulfamerazine derivatives as acetylcholinesterase and carbonic anhydrases inhibitors

I. Gulcin, H. Gul, Yeliz Demir, 2020, Archiv der Pharmazie.

New halogenated chalcones with cytotoxic and carbonic anhydrase inhibitory properties: 6‐(3‐Halogenated phenyl‐2‐propen‐1‐oyl)‐2(3H)‐benzoxazolones

I. Gulcin, H. Sakagami, H. Gul, 2020, Archiv der Pharmazie.

Synthesis, cytotoxicities, and carbonic anhydrase inhibition potential of 6-(3-aryl-2-propenoyl)-2(3H)-benzoxazolones

I. Gulcin, C. Supuran, H. Sakagami, 2019, Journal of enzyme inhibition and medicinal chemistry.

Novel sulphonamides incorporating triazene moieties show powerful carbonic anhydrase I and II inhibitory properties

I. Gulcin, C. Supuran, H. Gul, 2019, Journal of enzyme inhibition and medicinal chemistry.

Synthesis of Novel Bromophenol with Diaryl Methanes—Determination of Their Inhibition Effects on Carbonic Anhydrase and Acetylcholinesterase

I. Gulcin, Yeliz Demir, A. Maraş, 2022, Molecules.

Piperazine derivatives with potent drug moiety as efficient acetylcholinesterase, butyrylcholinesterase, and glutathione S‐transferase inhibitors

I. Gulcin, F. Türkan, L. Tamam, 2022, Journal of biochemical and molecular toxicology.

Pyrazole[3,4-d]pyridazine derivatives: Molecular docking and explore of acetylcholinesterase and carbonic anhydrase enzymes inhibitors as anticholinergics potentials.

I. Gulcin, F. Sen, P. Taslimi, 2019, Bioorganic chemistry.

Synthesis, structure elucidation, and in vitro pharmacological evaluation of novel polyfluoro substituted pyrazoline type sulfonamides as multi-target agents for inhibition of acetylcholinesterase and carbonic anhydrase I and II enzymes.

I. Gulcin, C. Yamali, H. Gul, 2020, Bioorganic chemistry.

Synthesis of benzamide derivatives with thiourea‐substituted benzenesulfonamides as carbonic anhydrase inhibitors

I. Gulcin, H. Gul, Yeliz Demir, 2020, Archiv der Pharmazie.

Inhibition effects of some pesticides and heavy metals on carbonic anhydrase enzyme activity purified from horse mackerel (Trachurus trachurus) gill tissues

I. Gulcin, P. Taslimi, Yeliz Demir, 2020, Environmental Science and Pollution Research.

The Influence of Some Nonsteroidal Anti-inflammatory Drugs on Metabolic Enzymes of Aldose Reductase, Sorbitol Dehydrogenase, and α-Glycosidase: a Perspective for Metabolic Disorders

I. Gulcin, P. Taslimi, Lokman Durmaz, 2020, Applied Biochemistry and Biotechnology.

The effects of zingerone against vancomycin‐induced lung, liver, kidney and testis toxicity in rats: The behavior of some metabolic enzymes

I. Gulcin, P. Taslimi, Yeliz Demir, 2019, Journal of biochemical and molecular toxicology.

The effects of hesperidin on sodium arsenite-induced different organ toxicity in rats on metabolic enzymes as antidiabetic and anticholinergics potentials: A biochemical approach.

I. Gulcin, P. Taslimi, Yeliz Demir, 2018, Journal of food biochemistry.

Oxidase Activity of Ceruloplasmin and Some Acute Phase Reactant and Trace Element Concentrations in Serum of Patients with Chronic Lymphocytic Leukemia

I. Gulcin, M. Gundogdu, H. Kaya, 2007, Scottish medical journal.

Inhibition Profiles of Some Symmetric Sulfamides Derived from Phenethylamines on Human Carbonic Anhydrase I, and II Isoenzymes

I. Gulcin, Fevzi Topal, F. Tümer, 2021, Chemistry & biodiversity.

The human carbonic anhydrase isoenzymes I and II inhibitory effects of some hydroperoxides, alcohols, and acetates

I. Gulcin, C. Supuran, S. Alwasel, 2016, Journal of enzyme inhibition and medicinal chemistry.

Antidiabetic properties of dietary phenolic compounds: Inhibition effects on α‐amylase, aldose reductase, and α‐glycosidase

I. Gulcin, Lokman Durmaz, Yeliz Demir, 2019, Biotechnology and applied biochemistry.

Investigation of acetylcholinesterase and mammalian DNA topoisomerases, carbonic anhydrase inhibition profiles, and cytotoxic activity of novel bis(α‐aminoalkyl)phosphinic acid derivatives against human breast cancer

I. Gulcin, O. Cevik, A. Çetin, 2017, Journal of biochemical and molecular toxicology.

Dual functional cholinesterase and carbonic anhydrase inhibitors for the treatment of Alzheimer's disease: Design, synthesis, in vitro, and in silico evaluations of coumarin-dihydropyridine derivatives

I. Gulcin, M. Adib, M. Mohammadi‐Khanaposhtani, 2023, Journal of Molecular Structure.

Screening of Antiglaucoma, Antidiabetic, Anti-Alzheimer, and Antioxidant Activities of Astragalus alopecurus Pall—Analysis of Phenolics Profiles by LC-MS/MS

I. Gulcin, S. Alwasel, F. D. Miloglu, 2023, Pharmaceuticals.

Comprehensive Metabolite Profiling of Berdav Propolis Using LC-MS/MS: Determination of Antioxidant, Anticholinergic, Antiglaucoma, and Antidiabetic Effects

I. Gulcin, S. Alwasel, Leyla Güven, 2023, Molecules.

Determination of Antioxidant, Anti-Alzheimer, Antidiabetic, Antiglaucoma and Antimicrobial Effects of Zivzik Pomegranate (Punica granatum)—A Chemical Profiling by LC-MS/MS

I. Gulcin, E. Kireççi, H. Karageçili, 2023, Life.

Synthesis of Schiff Bases Containing Phenol Rings and Investigation of Their Antioxidant Capacity, Anticholinesterase, Butyrylcholinesterase, and Carbonic Anhydrase Inhibition Properties

I. Gulcin, Zeynebe Bingol, S. Aytaç, 2023, Pharmaceutics.

Synthesis, characterization, Evaluation of Metabolic Enzyme Inhibitors and in silico Studies of Thymol Based 2-Amino Thiol and Sulfonic Acid Compounds.

I. Gulcin, M. Alagöz, M. Zengin, 2022, Chemico-biological interactions.

Synthesis, characterization, molecular docking and biological activities of novel pyrazoline derivatives

I. Gulcin, A. Cetin, Halide S Karaman, 2019, Archiv der Pharmazie.

Measurement of antioxidant ability of melatonin and serotonin by the DMPD and CUPRAC methods as trolox equivalent.

I. Gulcin, 2008, Journal of enzyme inhibition and medicinal chemistry.

Purification and characterization of the carbonic anhydrase enzyme from Black Sea trout (Salmo trutta Labrax Coruhensis) kidney and inhibition effects of some metal ions on enzyme activity.

I. Gulcin, M. Kucuk, 2016, Environmental toxicology and pharmacology.

Characterization and inhibition effects of some metal ions on carbonic anhydrase enzyme from Kangal Akkaraman sheep

I. Gulcin, U. M. Kocyigit, Parham Taslimi, 2018, Journal of biochemical and molecular toxicology.

The toxicological effects of some avermectins on goat liver carbonic anhydrase enzyme

I. Gulcin, C. Caglayan, Cuneyt Caglayan, 2018, Journal of biochemical and molecular toxicology.

Thymol regulates the Endothelin-1 at gene expression and protein synthesis levels in septic rats.

I. Gulcin, Başak Büyük, N. Kılınç, 2023, Chemico-biological interactions.

Synthesis, cytotoxicities, and carbonic anhydrase inhibition activities of pyrazoline–benzenesulfonamide derivatives harboring phenol/polyphenol moieties

I. Gulcin, Yeliz Demir, S. Bardaweel, 2022, Medicinal Chemistry Research.

Purification and characterization of dihydropyrimidine dehydrogenase enzyme from sheep liver and determination of the effects of some anaesthetic and antidepressant drugs on the enzyme activity

I. Gulcin, H. Özdemir, Y. Camadan, 2016, Journal of enzyme inhibition and medicinal chemistry.

Antibacterial and Acetylcholinesterase Inhibitory Potentials of Triazenes Containg Sulfonamide Moiety

I. Gulcin, H. Gul, S. Bilginer, 2021, Pharmaceutical Chemistry Journal.

The effects of wireless electromagnetic fields on the activities of carbonic anhydrase and acetylcholinesterase enzymes in various tissues of rats

I. Gulcin, S. Soylu, U. M. Kocyigit, 2018, Journal of biochemical and molecular toxicology.

Synthesis, biological activity and docking calculations of bis-naphthoquinone derivatives from Lawsone.

I. Gulcin, M. Khalid, M. Yaqub, 2021, Bioorganic chemistry.

DPPH Radical Scavenging Assay

I. Gulcin, S. Alwasel, 2023, Processes.

Cholinesterases, α-glycosidase, and carbonic anhydrase inhibition properties of 1H-pyrazolo[1,2-b]phthalazine-5,10-dione derivatives: Synthetic analogues for the treatment of Alzheimer's disease and diabetes mellitus.

I. Gulcin, F. Türkan, Z. Turgut, 2020, Bioorganic chemistry.

Design, Synthesis, Characterization and Biological Activities of Novel S‐(Acyloxy)butyl‐N,N‐Diethyldithiocarbamate Compounds

I. Gulcin, S. Alwasel, K. Mammadova, 2023, ChemistrySelect.

Co and Zn Metal Phthalocyanines with Bulky Substituents: Anticancer, Antibacterial Activities and Their Inhibitory Effects on Some Metabolic Enzymes with Molecular Docking Studies

E. Bursal, I. Gulcin, F. Türkan, 2021, Polycyclic Aromatic Compounds.

New Chalcone Derivatives with Pyrazole and Sulfonamide Pharmacophores as Carbonic Anhydrase Inhibitors

I. Gulcin, H. Gul, Hulya Akıncıoğlu, 2021, Letters in Drug Design & Discovery.

Synthesis and bioactivity studies on new 4-(3-(4-Substitutedphenyl)-3a,4-dihydro-3H-indeno[1,2-c]pyrazol-2-yl) benzenesulfonamides

I. Gulcin, C. Supuran, H. Sakagami, 2016, Journal of enzyme inhibition and medicinal chemistry.

Synthesis, characterization, biochemical, and molecular modeling studies of carvacrol‐based new thiosemicarbazide and 1,3,4‐thiadiazole derivatives

I. Gulcin, M. Zengin, M. Sadeghi, 2023, Archiv der Pharmazie.

Inhibition profile of a series of phenolic acids on bovine lactoperoxidase enzyme

I. Gulcin, H. Ozdemir, S. B. O. Sarikaya, 2015, Journal of enzyme inhibition and medicinal chemistry.

Synthesis, Characterization, Crystal Structure, Molecular Docking, and Biological Studies of Cu, Ni and Co Metal Complexes of Pyrazole

I. Gulcin, A. Sujayev, Vagif Farzaliyev, 2024, Journal of Molecular Structure.

Novel hydrazones derived from anthranilic acid as potent cholinesterases and α‐glycosidase inhibitors: Synthesis, characterization, and biological effects

I. Gulcin, T. Taşkın-Tok, F. S. Tokalı, 2023, Journal of biochemical and molecular toxicology.

Novel Quinazolinone Derivatives: Potential Synthetic Analogs for the Treatment of Glaucoma, Alzheimer's Disease and Diabetes Mellitus

I. Gulcin, F. S. Tokalı, A. Karakus, 2023, Chemistry & biodiversity.

Isofraxidin: Antioxidant, Anti‐carbonic Anhydrase, Anti‐cholinesterase, Anti‐diabetic, and in Silico Properties

I. Gulcin, Lokman Durmaz, B. Tüzün, 2023, ChemistrySelect.

Synthesis of new carboxylates and sulfonates containing thiazolidin-4-one ring and evaluation of inhibitory properties against some metabolic enzymes

I. Gulcin, B. Tüzün, F. S. Tokalı, 2023, Journal of the Iranian Chemical Society.

Synthesis of pyrrole-heterocyclic derivatives as anti-Alzheimer and antidiabetic candidates: An in vitro-in silico study

I. Gulcin, L. Sobenina, A. Sujayev, 2024, Journal of Molecular Structure.

Synthesis of 1,3‐Disubtitituted Tetrahydropyrimidinium Salts and Determination of Their Biological Properties and Molecular Docking

I. Gulcin, Yeliz Demir, B. Tüzün, 2024, ChemistrySelect.