P. Cowen

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Essential Psychopharmacology: Neuroscientific Basis and Practical Applications (2nd edn)

P. Cowen, 2002, British Journal of Psychiatry.

Effect of acute antidepressant administration on negative affective bias in depressed patients.

P. Cowen, C. Harmer, U. O’Sullivan, 2009, The American journal of psychiatry.

Normalization of enhanced fear recognition by acute SSRI treatment in subjects with a previous history of depression.

P. Cowen, C. Harmer, G. Goodwin, 2004, The American journal of psychiatry.

Effects of Citalopram Infusion on the Serotonin Transporter Binding of [11C]DASB in Healthy Controls

P. Cowen, P. Grasby, Z. Bhagwagar, 2008, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

The effects of tryptophan depletion on cognitive and affective processing in healthy volunteers

T. Robbins, P. Cowen, B. Sahakian, 2002, Psychopharmacology.

Increased Positive versus Negative Affective Perception and Memory in Healthy Volunteers following Selective Serotonin and Norepinephrine Reuptake Inhibition

P. Cowen, C. Harmer, G. Goodwin, 2022 .

Symptomatic relapse in bulimia nervosa following acute tryptophan depletion.

P. Cowen, K. Smith, C. Fairburn, 1999, Archives of general psychiatry.

Predictors of Mood Response to Acute Tryptophan Depletion: A Reanalysis

M. Fava, P. Cowen, C. Benkelfat, 2002, Neuropsychopharmacology.

A single dose of citalopram increases fear recognition in healthy subjects

P. Cowen, C. Harmer, G. Goodwin, 2007, Journal of psychopharmacology.

Acute SSRI Administration Affects the Processing of Social Cues in Healthy Volunteers

D. Perrett, P. Cowen, C. Harmer, 2003, Neuropsychopharmacology.

Low-dose tryptophan depletion in recovered depressed patients induces changes in cognitive processing without depressive symptoms

P. Cowen, C. Harmer, G. Goodwin, 2005, Biological Psychiatry.

Tryptophan depletion decreases the recognition of fear in female volunteers

P. Cowen, R. Rogers, C. Harmer, 2003, Psychopharmacology.

‘It's the way that you look at it’—a cognitive neuropsychological account of SSRI action in depression

P. Cowen, C. Harmer, 2013, Philosophical Transactions of the Royal Society B: Biological Sciences.

Shorter Oxford textbook of psychiatry

Paul J. Harrison, P. Cowen, M. Gelder, 2001 .

Brain mechanisms associated with depressive relapse and associated cognitive impairment following acute tryptophan depletion

Karl J. Friston, R. Dolan, P. Cowen, 1999, British Journal of Psychiatry.

Antidepressant Drug Treatment Modifies the Neural Processing of Nonconscious Threat Cues

Guy M. Goodwin, Clare E. Mackay, Catherine J. Harmer, 2006, Biological Psychiatry.

Methamphetamine Activates Reward Circuitry in Drug Naïve Human Subjects

Morten L Kringelbach, Paul M Matthews, Peter Jezzard, 2004, Neuropsychopharmacology.

SSRI administration reduces resting state functional connectivity in dorso-medial prefrontal cortex

P. Cowen, N. Filippini, C. Harmer, 2011, Molecular Psychiatry.

Low dose melatonin improves sleep in healthy middle-aged subjects

P. Cowen, M. Attenburrow, A. Sharpley, 1996, Psychopharmacology.

Melatonin phase advances circadian rhythm

P. Cowen, M. Attenburrow, A. Sharpley, 1995, Psychopharmacology.

The effects of serotonin modulation on medial prefrontal connectivity strength and stability: A pharmacological fMRI study with citalopram

P. Cowen, O. Howes, S. Selvaraj, 2018, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

The D2 antagonist sulpiride modulates the neural processing of both rewarding and aversive stimuli in healthy volunteers

P. Cowen, C. Harmer, C. McCabe, 2011, Psychopharmacology.

What has serotonin to do with depression?

P. Cowen, M. Browning, 2015, World psychiatry : official journal of the World Psychiatric Association.

Reduction of brain dopamine concentration with dietary tyrosine plus phenylalanine depletion: an [11C]raclopride PET study.

P. Cowen, P. Grasby, A. Montgomery, 2003, The American journal of psychiatry.

ABSTINENCE SYMPTOMS AFTER WITHDRAWAL OF TRANQUILLISING DRUGS: IS THERE A COMMON NEUROCHEMICAL MECHANISM?

P. Cowen, D. Nutt, 1982, The Lancet.

Neural representation of reward in recovered depressed patients

P. Cowen, C. Harmer, C. McCabe, 2009, Psychopharmacology.

Opposing neural effects of naltrexone on food reward and aversion: implications for the treatment of obesity

Catherine J. Harmer, Ciara McCabe, Philip J. Cowen, 2014, Psychopharmacology.

Cortisol, serotonin and depression: All stressed out?

P. Cowen, Cowen Pj, 2002, British Journal of Psychiatry.

Increase in concentration of waking salivary cortisol in recovered patients with depression.

P. Cowen, Z. Bhagwagar, S. Hafizi, 2003, The American journal of psychiatry.

Increased salivary cortisol after waking in depression

P. Cowen, Z. Bhagwagar, S. Hafizi, 2005, Psychopharmacology.

Effect of a single dose of citalopram on amygdala response to emotional faces

Catherine J. Harmer, Susannah E. Murphy, Philip J. Cowen, 2009, British Journal of Psychiatry.

Adverse effects from antidepressant treatment: randomised controlled trial of 601 depressed individuals

Glyn Lewis, Nicola Wiles, Tim J. Peters, 2014, Psychopharmacology.

How do antidepressants work? New perspectives for refining future treatment approaches.

Ronald S Duman, P. Cowen, C. Harmer, 2017, The lancet. Psychiatry.

Why do antidepressants take so long to work? A cognitive neuropsychological model of antidepressant drug action

P. Cowen, C. Harmer, G. Goodwin, 2009, British Journal of Psychiatry.

Brain glutamate in anorexia nervosa: a magnetic resonance spectroscopy case control study at 7 Tesla

Uzay E. Emir, Philip J. Cowen, Beata R. Godlewska, 2016, Psychopharmacology.

Efficacy markers in depression

P. Cowen, C. Harmer, G. Goodwin, 2011, Journal of psychopharmacology.

Effects of Depression and Antidepressant Treatment

P. Cowen, P. Grasby, C. Bench, 2016 .

Antiepileptic drugs prescribed in pregnancy and prevalence of major congenital malformations: comparative prevalence studies

P. Cowen, I. Petersen, I. Nazareth, 2017, Clinical epidemiology.

Discontinuation of antipsychotic medication in pregnancy: A cohort study

P. Cowen, I. Petersen, I. Nazareth, 2014, Schizophrenia Research.

The effect of clonidine and bright light on plasma melatonin

P. Cowen, P. Grasby, P. M. Grasby, 1988 .

CSF1R inhibitor JNJ-40346527 attenuates microglial proliferation and neurodegeneration in P301S mice

Caleb Webber, Guy B. Williams, Mara Cercignani, 2019, Brain : a journal of neurology.

CHAPTER 2 - Antidepressant drugs

P. Cowen, 2009 .

Cerebellar responses during anticipation of noxious stimuli in subjects recovered from depression. Functional magnetic resonance imaging study.

P M Matthews, P. Matthews, P. Cowen, 2002, The British journal of psychiatry : the journal of mental science.

Preferential 5-HT1A Autoreceptor Occupancy by Pindolol is Attenuated in Depressed Patients: Effect of Treatment or an Endophenotype of Depression?

P. Cowen, P. Grasby, Z. Bhagwagar, 2004, Neuropsychopharmacology.

Drug action at the 5-HT(1A) receptor in vivo: autoreceptor and postsynaptic receptor occupancy examined with PET and [carbonyl-(11)C]WAY-100635.

P. Cowen, P. Grasby, E. Rabiner, 2000, Nuclear medicine and biology.

Brain serotonin1A receptor binding measured by positron emission tomography with [11C]WAY-100635: effects of depression and antidepressant treatment.

P A Sargent, R N Gunn, P. Cowen, 2000, Archives of general psychiatry.

Assessment and treatment of insomnia (including a case control study of patients with Primary Insomnia).

P. Cowen, M. Attenburrow, A. Sharpley, 1997, International journal of psychiatry in clinical practice.

Case-control study of evening melatonin concentration in primary insomnia

P. Cowen, M. Attenburrow, A. Sharpley, 1996, BMJ.

Treatment with beta-adrenoceptor blockers reduces plasma melatonin concentration.

P. Cowen, J. Bevan, B. Gosden, 1985, British journal of clinical pharmacology.

5-HT and depression: is the glass half-full?

Trevor Sharp, P. Cowen, T. Sharp, 2011, Current opinion in pharmacology.

Effect of Citalopram on Emotion Processing in Humans: A combined 5-HT1A [11C]CUMI-101 PET and functional MRI Study

P. Cowen, J. Roiser, O. Howes, 2018, Neuropsychopharmacology.

Increased 5-HT2A receptor binding in euthymic, medication free recovered depressed patients: a positron emission study with [11C]MDL100907.

P. Cowen, P. Grasby, Z. Bhagwagar, 2006 .

Mediation of ACTH and prolactin responses to 5-HTP by 5-HT2 receptors.

P. Cowen, S. E. Gartside, 1990, European journal of pharmacology.

P.2.b.017 Structural brain alterations in major depression: findings from the ENIGMA Major Depressive Disorder Working Group

Lachlan T. Strike, I. Hickie, N. Jahanshad, 2015, European Neuropsychopharmacology.

Not fade away: the HPA axis and depression

P. Cowen, 2009, Psychological Medicine.

p-Chloroamphetamine (PCA), 3,4-methylenedioxymethamphetamine (MDMA) andd-fenfluramine pretreatment attenuatesd-fenfluramine-evoked release of 5-HT in vivo

P. Cowen, T. Sharp, H. Series, 1994, Psychopharmacology.

Decreased sensitivity of 5-HT1D receptors in melancholic depression

P. Cowen, Z. Bhagwagar, R. Whale, 2001, British Journal of Psychiatry.

Zolmitriptan-induced growth hormone release in humans: mediation by 5-HT1D receptors?

P. Cowen, Z. Bhagwagar, R. Whale, 1999, Psychopharmacology.

Increased slow wave sleep with 5-HT2 receptor antagonists: detection by ambulatory EEG recording and automatic sleep stage analysis

P. Cowen, A. Sharpley, R. Solomon, 1989, Journal of psychopharmacology.

Effects of the potential lithium-mimetic, ebselen, on brain neurochemistry: a magnetic resonance spectroscopy study at 7 tesla

P. Cowen, S. Vasudevan, G. Churchill, 2016, Psychopharmacology.

The effect of a nutritional source of tryptophan on dieting-induced changes in brain 5-HT function

P. Cowen, J. Powell, M. Attenburrow, 2003, Psychological Medicine.

Ondansetron and Opiate Craving

P. Cowen, L. Sell, P. Robson, 1995, British Journal of Psychiatry.

An experimental medicine study of the effects of simvastatin on emotional processing, reward learning, verbal memory, and inflammation in healthy volunteers

P. Cowen, C. Harmer, Riccardo De Giorgi, 2022, Psychopharmacology.

2 - Antidepressant drugs

P. Cowen, 2007 .

Erythropoietin modulates neural and cognitive processing of emotional information in biomarker models of antidepressant drug action in depressed patients

P. Cowen, C. Harmer, E. Favaron, 2010, Psychopharmacology.

Risk of Depression in the Adolescent and Adult Offspring of Mothers With Perinatal Depression

P. Cowen, S. Selvaraj, Jonathan Evans, 2020, JAMA network open.

No evidence for differential gene expression in major depressive disorder PBMCs, but robust evidence of elevated biological ageing

E. Bullmore, P. Cowen, M. Lynall, 2020, Translational Psychiatry.

The effects of statin monotherapy on depressive symptoms: A systematic review and meta-analysis.

P. Cowen, C. Harmer, Riccardo De Giorgi, 2022, Journal of affective disorders.

Title page: Frontal cortex stimulation reduces vigilance to threat: implications for the treatment of depression and anxiety

P. Cowen, M. Ironside, Dr. Jacinta O’Shea, 2016 .

Lithium modulates striatal reward anticipation and prediction error coding in healthy volunteers

P. Cowen, C. Harmer, M. Browning, 2020, Neuropsychopharmacology.

When less is more: a functional magnetic resonance imaging study of verbal working memory in remitted depressed patients

P. Cowen, B. Godlewska, R. Norbury, 2013, Psychological Medicine.

Frontolimbic responses to emotional faces in young people at familial risk of depression.

P. Cowen, C. Harmer, Matthew J. Taylor, 2011, Journal of affective disorders.

Affective modulation of anterior cingulate cortex in young people at increased familial risk of depression

P. Cowen, C. Harmer, B. Inkster, 2008, British Journal of Psychiatry.

A Delphi-method-based consensus guideline for definition of treatment-resistant depression for clinical trials

M. Leboyer, A. Meyer-Lindenberg, R. Shelton, 2021, Molecular Psychiatry.

Structural and functional imaging of the hippocampus in young people at familial risk of depression

P. Cowen, N. Filippini, C. Mackay, 2014, Psychological Medicine.

Reduction in occipital cortex GABA concentrations in medication free recovered bipolar subjects

P. Matthews, P. Cowen, P. Jezzard, 2007 .

Normal glutamate but elevated myo-inositol in anterior cingulate cortex in recovered depressed patients

P. Cowen, P. Jezzard, S. Selvaraj, 2009, Journal of affective disorders.

When Helping is Risky: The Behavioral and Neurobiological Tradeoff of Social and Risk Preferences

P. Cowen, C. D. De Dreu, M. Crockett, 2020, Psychological science.

Early markers of cognitive enhancement: developing an implicit measure of cognitive performance

P. Cowen, C. Harmer, M. Browning, 2013, Psychopharmacology.

Serotonin – 100 words

P. Cowen, 2013, British Journal of Psychiatry.

Neuroendocrine Effects of Azapirones

P. Cowen, I. Anderson, D. Grahame-Smith, 1990, Journal of clinical psychopharmacology.

Intravenous l-tryptophan and regional cerebral blood flow

P. Cowen, G. Goodwin, B. Shepstone, 1991, Biological Psychiatry.

Comparative effects of pharmacological interventions for the acute and long-term management of insomnia disorder in adults: a systematic review and network meta-analysis

P. Cowen, D. Quested, F. Crescenzo, 2022, The Lancet.

Biological markers of depression

P. Cowen, A. J. Wood, 1991, Psychological Medicine.

Decreased sensitivity of 5-HT1D receptors in melancholic depression

P. Cowen, Z. Bhagwagar, R. Whale, 2001, British Journal of Psychiatry.

Contrasting effects of citalopram and reboxetine on waking salivary cortisol

P. Cowen, C. Harmer, Z. Bhagwagar, 2003, Psychopharmacology.

Sertraline treatment does not increase plasma prolactin levels in healthy subjects

P. Cowen, R. Whale, C. Gordon, 1998, Psychopharmacology.

Presynaptic Serotoninergic Regulation of Emotional Processing: A Multimodal Brain Imaging Study

F. Turkheimer, P. Cowen, J. Roiser, 2015, Biological Psychiatry.

Effect of moderate weight loss on prolactin secretion in normal female volunteers

P. Cowen, I. Anderson, E. Newsholme, 1989, Psychiatry Research.

Can saliva testing replace blood measurements for health monitoring? Insights from a correlation study of salivary and whole blood glutathione in humans.

P. Cowen, R. Compton, L. M. Gonçalves, 2016, The Analyst.

Increased platelet membrane [3H]-LSD binding in patients on chronic neuroleptic treatment.

P. Cowen, D. Grahame-Smith, J. Elliott, 1985, British journal of clinical pharmacology.

Tyrosine depletion attenuates the behavioural stimulant effects of amphetamine and cocaine in rats.

P. Cowen, B. Raumann, T. Sharp, 2001, European journal of pharmacology.

Nefazodone—A novel antidepressant— May increase REM sleep

P. Cowen, A. Sharpley, A. Walsh, 1992, Biological Psychiatry.

Lack of effect of hydrocortisone treatment on d-fenfluramine-mediated prolactin release

A. Young, P. Cowen, J. Odontiadis, 1998, Psychopharmacology.

Brain serotonin (5-HT) neuroendocrine function in patients taking cholesterol-lowering drugs

P. Cowen, D. Matthews, N. Delva, 1996, Biological Psychiatry.

Acute citalopram administration produces correlated increases in plasma and salivary cortisol

P. Cowen, Z. Bhagwagar, S. Hafizi, 2002, Psychopharmacology.

Ondansetron, a 5‐HT3 receptor antagonist, partially attenuates the effects of amphetamine: a pilot study in healthy volunteers

P. Cowen, P. Silverstone, B. Johnson, 1992, International clinical psychopharmacology.

Hypophagic, endocrine and subjective responses to m‐chlorophenylpiperazine in healthy men and women

P. Cowen, P. Sargent, E. Goodall, 1995 .

Sumatriptan decreases food intake and increases plasma growth hormone in healthy women

P. Cowen, E. Goodall, S. Boeles, 1997, Psychopharmacology.

β-Adrenoceptor agonists enhance the functional activity of brain 5-hydroxytryptamine: relationship to antidepressant activity

P. Cowen, V. Nimgaonkar, A. R. Green, 1983 .

Attention-Deficit and Disruptive Behavior Disorders

C. McDougle, D. Posey, C. Buhusi, 2014 .

Attention Deficit Hyperactivity Disorders: Animal Models

C. McDougle, D. Posey, C. Buhusi, 2014 .

Neuroendocrine effects of sumatriptan

P. Cowen, N. Delva, G. Campling, 2005, Psychopharmacology.

Statins in depression: a repurposed medical treatment can provide novel insights in mental health

P. Cowen, C. Harmer, Riccardo De Giorgi, 2022, International review of psychiatry.

Psychobiotics Highlight the Pathways to Happiness

P. Cowen, P. Burnet, 2013, Biological Psychiatry.

Fos immunocytochemical studies on the neuroanatomical sites of action of acute tyrosine depletion in the rat brain

P. Cowen, T. Sharp, M. L. Masurier, 2004, Psychopharmacology.

The development and use of a standardized assessment of abnormal personality

P. Cowen, A. Mann, R. Jenkins, 1981, Psychological Medicine.

Acute neural effects of fluoxetine on emotional regulation in depressed adolescents

P. Cowen, N. Filippini, C. Harmer, 2022, Psychological Medicine.

Peripheral blood cell immunophenotyping reveals distinct subgroups of inflamed depression

E. Bullmore, P. Cowen, M. Lynall, 2019, bioRxiv.

The Potential Use of Ebselen in Treatment-Resistant Depression

P. Cowen, B. Godlewska, Fitri Fareez Ramli, 2022, Pharmaceuticals.

Overnight transdermal scopolamine patch administration has no clear effect on cognition and emotional processing in healthy volunteers

P. Cowen, C. Harmer, M. Browning, 2018, Journal of psychopharmacology.

A role for 5-HT 4 receptors in human learning and memory

P. Cowen, C. Harmer, M. Browning, 2019 .

How do drugs for psychiatric disorders work?

P. Cowen, C. Harmer, 2017, Epidemiology and Psychiatric Sciences.

Drug information update: agomelatine

P. Cowen, D. Whiting, 2013 .

Plasma melatonin during desmethylimipramine treatment: evidence for changes in noradrenergic transmission.

P. Cowen, A. R. Green, L. Braddock, 1985, British journal of clinical pharmacology.

Peripheral Blood Cell–Stratified Subgroups of Inflamed Depression

E. Bullmore, P. Cowen, M. Lynall, 2019, Biological Psychiatry.

Altered states: psilocybin for treatment-resistant depression.

P. Cowen, 2016, The lancet. Psychiatry.

Disease, Normality, and Current Pharmacological Moral Modification

P. Cowen, T. Douglas, J. Savulescu, 2014 .

The effect of moderate weight loss on overnight growth hormone and cortisol secretion in healthy female volunteers.

P. Cowen, I. Anderson, C. Fairburn, 1989, Journal of affective disorders.

β‐ADRENOCEPTOR AGONISTS ENHANCE 5‐HYDROXYTRYPTAMINE‐MEDIATED BEHAVIOURAL RESPONSES

P. Cowen, A. R. Green, D. Heal, 1982, British journal of pharmacology.

Behavioral Neurobiology of Depression and Its Treatment

P. Cowen, T. Sharp, Lau Jyf, 2013, Current Topics in Behavioral Neurosciences.

Experimental medicine model shows no depressogenic effects of varenicline

L. Parsons, P. Cowen, C. Harmer, 2012 .

Sleep and 5-HT2 receptor sensitivity in recovered depressed patients.

P. Cowen, A. Sharpley, R. Solomon, 1992, Journal of affective disorders.

Direct radioimmunoassay for melatonin in plasma.

P. Cowen, J. Arendt, C. Franey, 1983, Clinical chemistry.

The pineal and psychiatry: still fumbling in the dark?

P. Cowen, P. Grasby, 1987, Psychological Medicine.

Atenolol reduces plasma melatonin concentration in man.

P. Cowen, R. Sammons, A. R. Green, 1983, British journal of clinical pharmacology.

Bright Light Blocks Amitriptyline-Induced Cholinoceptor Supersensitivity

P. Cowen, R. Sammons, S. Fraser, 1989 .

CHANGES IN PLATELET α2-ADRENOCEPTOR BINDING POST PARTUM: POSSIBLE RELATION TO MATERNITY BLUES

P. Cowen, M. Gelder, D. Grahame-Smith, 1983, The Lancet.

Changes in the binding to platelets of [3H]imipramine and [3H]yohimbine in normal subjects taking amitriptyline

P. Cowen, L. Braddock, J. Elliott, 1984, Neuropharmacology.

Effect of pindolol on endocrine and temperature responses to buspirone in healthy volunteers

P. Cowen, I. Anderson, 1992, Psychopharmacology.

The effect of Li 1370, extract of Ginkgo biloba, on REM sleep in humans.

P. Cowen, A. Sharpley, B. Murray, 2001, Pharmacopsychiatry.

Researching the Antidepressant Actions of Hypericum Perforatum (St. John’s wort) in Animals and Man

P. Cowen, M. Franklin, 2001, Pharmacopsychiatry.

Studies on the mechanisms by which clenbuterol, a β-adrenoceptor agonist, enhances 5-HT-mediated behaviour and increases metabolism of 5-HT in the brain of the rat

P. Cowen, V. Nimgaonkar, A. R. Green, 1983, Neuropharmacology.

Allelic variation of the 5-HT2C receptor (HTR2C) in bulimia nervosa and binge eating disorder.

Paul J. Harrison, P. Cowen, K. Smith, 1999, Psychiatric genetics.

Repeated administration of subconvulsant doses of GABA antagonist drugs

P. Cowen, D. Nutt, D. Heal, 2004, Psychopharmacology.

Chromium treatment decreases the sensitivity of 5-HT2A receptors

P. Cowen, M. Attenburrow, M. Franklin, 2002, Psychopharmacology.

Efficacy, safety and tolerability of duloxetine 60 mg once daily in major depression.

P. Cowen, A. Ogilvie, J. Gama, 2005, Current medical research and opinion.

Neuroendocrine and Neurochemical Processes in Depression

P. Cowen, 2016 .

Personality and psychosis: use of the Standardized Assessment of Personality

P. Cowen, A. Mann, R. Jenkins, 1986, Acta psychiatrica Scandinavica.

Changes in plasma prolactin during SSRI treatment: evidence for a delayed increase in 5-HT neurotransmission

P. Cowen, P. Sargent, 1997, Journal of psychopharmacology.

Diminished brain 5-HT transporter binding in major depression: a positron emission tomography study with [11C]DASB

Subrata K. Bose, Zubin Bhagwagar, Rainer Hinz, 2011, Psychopharmacology.

Effect of estradiol implant on noradrenergic function and mood in menopausal subjects

P. Cowen, D. Barlow, N. Best, 1992, Psychoneuroendocrinology.

Binding of tritiated yohimbine to platelets in women with maternity blues

P. Cowen, J. Elliott, K. Stump, 1988, Psychological Medicine.

Effects of the contraceptive pill on sedative responses to clonidine and apomorphine in normal women

P. Cowen, J. S. Chalmers, I. Fulli-Lemaire, 1985, Psychological Medicine.

Acute administration of nutritionally sourced tryptophan increases fear recognition

P. Cowen, C. Harmer, J. Powell, 2003, Psychopharmacology.

Responses of prolactin and growth hormone to L-tryptophan infusion: Effects in normal subjects and schizophrenic patients receiving neuroleptics

P. Cowen, B. Gosden, T. Kołakowska, 2004, Psychopharmacology.

The 5-HT3 antagonist, BRL 46470 does not attenuate m-chlorophenylpiperazine (mCPP)-induced changes in human volunteers

P. Cowen, P. Silverstone, 1994, Biological Psychiatry.

Does agomelatine block 5-HT2C receptors in humans?

P. Cowen, N. Rawlings, A. Sharpley, 2011, Psychopharmacology.

Neuroendocrine responses to intravenous L-tryptophan in obsessive compulsive disorder.

P. Cowen, N. Fineberg, S. Montgomery, 1994, Journal of affective disorders.

Neuroendocrine probes for 5-HT receptor subtypes

P. Cowen, 1993, European Neuropsychopharmacology.

Neuroendocrine and temperature effects of nefazodone in healthy volunteers

P. Cowen, A. Walsh, G. Campling, 1993, Biological Psychiatry.

L‐Tryptophan and prolactin release: Evidence for interaction between 5‐HT1 and 5‐HT2 receptors

P. Cowen, D. Nutt, I. Anderson, 1986 .

The effects of dieting and weight loss upon the stimulation of thyrotropin (TSH) by thyrotropin-releasing hormone (TRH) and suppression of cortisol secretion by dexamethasone in men and women.

P. Cowen, G. Goodwin, C. Fairburn, 1988, Journal of affective disorders.

Short-term antidepressant treatment and facial processing

P. Cowen, C. Harmer, G. Goodwin, 2007, British Journal of Psychiatry.

Commentary on 'The management of treatment-resistant affective disorder: clinical perspectives'

P. Cowen, 1992, Journal of psychopharmacology.

Psychotropic drugs and human 5-HT neuroendocrinology

P. Cowen, 1987 .

Effect of 5-hydroxy-l-tryptophan on the release of 5-HT in rat hypothalamus in vivo as measured by microdialysis

P. Cowen, S. E. Gartside, T. Sharp, 1992, Neuropharmacology.

Attenuation of some subjective effects of amphetamine following tyrosine depletion

P. Cowen, T. Sharp, S. Mctavish, 1999, Journal of psychopharmacology.

Short-term antidepressant treatment modulates amygdala response to happy faces

P. Cowen, C. Harmer, S. Selvaraj, 2009, Psychopharmacology.

Tyrosine-free amino acid mixtures reduce physiologically-evoked release of dopamine in a selective and activity-dependent manner

P. Cowen, T. Sharp, T. Zetterström, 2014, Journal of psychopharmacology.

Effect of Acute Tyrosine Depletion in Using a Branched Chain Amino-Acid Mixture on Dopamine Neurotransmission in the Rat Brain

P. Cowen, T. Sharp, M. L. Masurier, 2006, Neuropsychopharmacology.

Brain Serotonin Release Is Reduced in Patients With Depression: A [11C]Cimbi-36 Positron Emission Tomography Study With a d-Amphetamine Challenge

P. Cowen, O. Howes, J. Passchier, 2022, Biological Psychiatry.

A dose-finding study on the effects of branch chain amino acids on surrogate markers of brain dopamine function

P. Cowen, C. Harmer, G. Goodwin, 2002, Psychopharmacology.

Pharmacological targeting of cognitive impairment in depression: recent developments and challenges in human clinical research

P. Cowen, C. Harmer, S. Murphy, 2022, Translational Psychiatry.

‘It's not over when it's over’: persistent neurobiological abnormalities in recovered depressed patients

P. Cowen, Z. Bhagwagar, 2007, Psychological Medicine.

Acute and chronic idazoxan in normal volunteers: biochemical, physiological and psychological effects

P. Cowen, D. Nutt, Sue J. Wilson, 1991, Journal of psychopharmacology.

Do the endocrine and subjective effects of d‐fenfluramine predict response to selective serotonin reuptake inhibitors?

P. Cowen, S. B. Park, D. Williamson, 1995, International clinical psychopharmacology.

Effects of seven-day diazepam administration on resting-state functional connectivity in healthy volunteers: a randomized, double-blind study

P. Cowen, N. Filippini, C. Harmer, 2015, Psychopharmacology.

Desipramine treatment in normal subjects. Effects on neuroendocrine responses to tryptophan and on platelet serotonin (5-HT)-related receptors.

P. Cowen, A. R. Green, J. Elliott, 1986, Archives of general psychiatry.

Endocrine responses to tryptophan infusion in schizophrenic patients treated with neuroleptics

P. Cowen, T. Kołakowska, P. Murdock, 1987, Psychoneuroendocrinology.

HALOPERIDOL INCREASES LATENT INHIBITION IN HIGH SCHIZOTYPAL SUBJECTS

J. Rawlins, P. Cowen, J. Feldon, 1994 .

meta-Chlorophenylpiperazine decreases slow-wave sleep in humans

P. Cowen, A. Sharpley, Y. Katsuda, 1993, Biological Psychiatry.

The effects of gepirone on neuroendocrine function and temperature in humans

P. Cowen, I. Anderson, D. Grahame-Smith, 2005, Psychopharmacology.

Endocrinological Responses to 5‐HT a

P. Cowen, I. Anderson, S. Gartside, 1990, Annals of the New York Academy of Sciences.

5-HT 2C receptor sensitivity during treatment with selective serotonin re-uptake inhibitors

P. Cowen, A. Sharpley, R. Williams, 1994, Journal of psychopharmacology.

Alpha-2-adrenoceptor control of cortisol and ACTH in normal volunteers: Preliminary open trial of the effects of acute and chronic idazoxan

P. Cowen, D. Nutt, Sue J. Wilson, 1992, Psychoneuroendocrinology.

Diminished Neural Processing of Aversive and Rewarding Stimuli During Selective Serotonin Reuptake Inhibitor Treatment

P. Cowen, C. Harmer, C. McCabe, 2010, Biological Psychiatry.

Menstrual cycle effects on the action of buspirone on food intake in healthy female volunteers

P. Cowen, T. Silverstone, M. Whittle, 1995, Journal of psychopharmacology.

Effects of short-term varenicline administration on cortisol in healthy, non-smoking adults: a randomized, double-blind, study

P. Cowen, C. Harmer, A. Schene, 2013, Psychopharmacology.

Effect of oestradiol treatment on 5-HT and dopamine-mediated neuroendocrine responses

P. Cowen, D. Barlow, D. Barlow, 1992, Journal of psychopharmacology.

Neuroendocrine responses to L-tryptophan as an index of brain serotonin function: effect of weight loss.

P. Cowen, I. Anderson, 1991, Advances in experimental medicine and biology.

Unusual interactions of benzodiazepine receptor antagonists

P. Cowen, D. Nutt, H. Little, 1982, Nature.

Attenuation of preferential occupancy of 5-HT1A autoreceptors by pindolol in depressed patients: effect of SSRIs or an endophenotype of the depressed state?

P. Cowen, P. Grasby, C. Bench, 2002 .

Platelet Monoamine Receptor Binding and Tricyclic Antidepressant Treatment

P. Cowen, L. Braddock, 1990 .

The effect of diazepam on indices of 5-HT function in man

P. Cowen, D. Nutt, B. Gosden, 1986, Pharmacology Biochemistry and Behavior.

Review: no evidence exists that antidepressants acting at >1 pharmacological site differ in efficacy from SSRIs in major depression

P. Cowen, 2001 .

Altered in vitro adaptive responses of lymphocyte Na+,K(+)-ATPase in patients with manic depressive psychosis.

P. Cowen, J. Aronson, D. Grahame-Smith, 1991, Journal of affective disorders.

Abnormal 5-HT neuroendocrine function in depression: association or artefact?

P. Cowen, I. Anderson, 1991 .

Acute Reboxetine Administration Increases Plasma and Salivary Cortisol

P. Cowen, C. Harmer, M. Taylor, 2003, Journal of psychopharmacology.

The price of coffins: specious arguments by eminent doctors against the dangers of tobacco

P. Cowen, 1999, BMJ.

Single photon emission tomography assessment of cerebral dopamine D2 receptor blockade in schizophrenia

P. Cowen, B. Shepstone, N. Soper, 1992, Biological Psychiatry.

A Dissociation of the Acute Effects of Bupropion on Positive Emotional Processing and Reward Processing in Healthy Volunteers

P. Cowen, C. Harmer, M. Browning, 2018, Front. Psychiatry.

Brain Imaging and the Mechanisms of Antidepressant Action

Philip J. Cowen, Beata R. Godlewska, Sudhakar Selvaraj, 2021 .

Are You Morally Modified?: The Moral Effects of Widely Used Pharmaceuticals

P. Cowen, J. Savulescu, M. Hewstone, 2014, Philosophy, psychiatry, & psychology : PPP.

Changes in Mood, Appetite and Psychomotor Retardation in Depressed Patients Given ECT

P. Cowen, S. Browning, 1986, British Journal of Psychiatry.

Memory impairment in young women at increased risk of depression: influence of cortisol and 5-HTT genotype

P. Cowen, C. Harmer, Z. Mannie, 2008, Psychological Medicine.

Back to the future: the neurobiology of major depression

P. Cowen, 1998, Psychological Medicine.

Studies on the post-ictal rise in seizure threshold.

P. Cowen, D. Nutt, A. Green, 1981, European journal of pharmacology.

Noradrenaline effects on social behaviour, intergroup relations, and moral decisions

P. Cowen, L. P. Chesterman, S. Terbeck, 2016, Neuroscience & Biobehavioral Reviews.

Neural Effects of Cannabinoid CB1 Neutral Antagonist Tetrahydrocannabivarin on Food Reward and Aversion in Healthy Volunteers

P. Cowen, C. McCabe, Luke Tudge, 2015, The international journal of neuropsychopharmacology.

On the measurement in rats of the convulsant effect of drugs and the changes which follow electroconvulsive shock

P. Cowen, D. Nutt, A. Green, 1980, Neuropharmacology.

Benzodiazepine-serotonin interactions in man.

P. Cowen, D. Nutt, 1987, Psychopharmacology series.

Neurochemical abnormalities in chronic fatigue syndrome: a pilot magnetic resonance spectroscopy study at 7 Tesla

Ana Jorge Gonçalves, William T. Clarke, P. Cowen, 2021, Psychopharmacology.

Brain glutamate concentration in men with early psychosis: a magnetic resonance spectroscopy case–control study at 7 T

P. Cowen, O. Howes, B. Lennox, 2021, Translational Psychiatry.

Brain glutamate in medication-free depressed patients: a proton MRS study at 7 Tesla

P. Cowen, B. Godlewska, U. Emir, 2017, Psychological Medicine.

Ketamine and other glutamate receptor modulators for depression in adults with unipolar major depressive disorder.

P. Cowen, A. Cipriani, E. Turner, 2021, The Cochrane database of systematic reviews.

Statins for major depressive disorder: A systematic review and meta-analysis of randomized controlled trials

P. Cowen, C. Harmer, F. De Crescenzo, 2021, PloS one.

Single dose antidepressant administration modulates the neural processing of self-referent personality trait words

Guy M. Goodwin, Catherine J. Harmer, Kamilla Miskowiak, 2007, NeuroImage.

Effect of pharmacologic treatments on the sleep of depressed patients

P. Cowen, A. Sharpley, 1995, Biological Psychiatry.

Neuroendocrine Responses to Tryptophan as an Index of Brain Serotonin Function

P. Cowen, 1988 .

Neuroendocrine responses to intravenous tryptophan in major depression.

P. Cowen, E. Charig, 1987, Archives of general psychiatry.

Pindolol augmentation of serotonin reuptake inhibitors for the treatment of depressive disorder: a systematic review

N. Freemantle, P. Cowen, T. Terao, 2010, Journal of psychopharmacology.

Prebiotic intake reduces the waking cortisol response and alters emotional bias in healthy volunteers

P. Cowen, C. Harmer, G. Tzortzis, 2014, Psychopharmacology.

Frontal Cortex Stimulation Reduces Vigilance to Threat: Implications for the Treatment of Depression and Anxiety

P. Cowen, C. Harmer, M. Ironside, 2016, Biological Psychiatry.

Increased waking salivary cortisol levels in young people at familial risk of depression.

P. Cowen, C. Harmer, Z. Mannie, 2007, The American journal of psychiatry.

The effect of chronic antidepressant administration on β‐adrenoceptor function of the rat pineal

P. Cowen, D. Grahame-Smith, C. Stanford, 1983, British journal of pharmacology.

Effect of lofepramine on 5-HT function and sleep.

P. Cowen, A. Sharpley, D. Laver, 1993, Journal of affective disorders.

Reduced latent inhibition in people with schizophrenia: an effect of psychosis or of its treatment

J. Rawlins, P. Cowen, J. Feldon, 1998, British Journal of Psychiatry.

Haloperidol enhances latent inhibition in visual tasks in healthy people

J. Rawlins, P. Cowen, J. Feldon, 1997, Psychopharmacology.

Antipsychotic drug effects in a model of schizophrenic attentional disorder: A randomized controlled trial of the effects of haloperidol on latent inhibition in healthy people

J. Rawlins, P. Cowen, J. Feldon, 1996, Biological Psychiatry.

5-HT1A Receptor Sensitivity in Major Depression

P. Cowen, I. Anderson, C. J. Ware, 1994, British Journal of Psychiatry.

Does baseline fatigue influence treatment response to reboxetine or citalopram in depression? An open label randomized controlled trial

T. Peters, P. Cowen, D. Nutt, 2012, Journal of psychopharmacology.

β-blocker Binding to Human 5-HT1A Receptors in vivo and in vitro: Implications for Antidepressant Therapy

Paul J. Harrison, P. Cowen, P. Grasby, 2000, Neuropsychopharmacology.

Fluoxetine and Suicidal Behaviour

P. Cowen, A. C. Power, 1992, British Journal of Psychiatry.

Comparison of the effects of chronic desmethylimipramine administration on α2- and β-adrenoceptors in different regions of rat brain

P. Cowen, D. Nutt, C. Stanford, 1983, Neuroscience.

Comparison of the effects of a-methyl-p-tyrosine and a tyrosine-free amino acid load on extracellular noradrenaline in the rat hippocampus in vivo

P. Cowen, T. Sharp, L. Callado, 1999, Journal of psychopharmacology.

The pharmacokinetics of L-tryptophan following its intravenous and oral administration.

P. Cowen, J. Aronson, A. Green, 1985, British journal of clinical pharmacology.

Early changes in emotional processing as a marker of clinical response to SSRI treatment in depression

P. Cowen, C. Harmer, M. Browning, 2016, Translational psychiatry.

A 5‐HT2C receptor promoter polymorphism (HTR2C − 759C/T) is associated with obesity in women, and with resistance to weight loss in heterozygotes

Paul J. Harrison, P. Cowen, C. Fairburn, 2004, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

Treatment-resistant depression and peripheral C-reactive protein

E. Bullmore, P. Cowen, W. Drevets, 2017, bioRxiv.

The Measurement of Transmembrane Cation Transport in vivo in Acute Manic Illness

P. Cowen, J. Aronson, D. Grahame-Smith, 1989, British Journal of Psychiatry.

Dysconnectivity of a brain functional network was associated with blood inflammatory markers in depression

E. Bullmore, P. Cowen, P. Vértes, 2021, Brain, Behavior, and Immunity.

Direct radioimmunoassay and gas chromatography-mass spectrometry compared for determination of melatonin in plasma.

P. Cowen, A. Lewy, S. Fraser, 1983, Clinical chemistry.

How Cannabis Causes Paranoia: Using the Intravenous Administration of ∆9-Tetrahydrocannabinol (THC) to Identify Key Cognitive Mechanisms Leading to Paranoia

Paul J. Harrison, R. Murray, G. Dunn, 2014, Schizophrenia bulletin.

Evidence that the large neutral amino acidl-valine decreases electrically-evoked release of 5-HT in rat hippocampus in vivo

P. Cowen, S. E. Gartside, T. Sharp, 2005, Psychopharmacology.

Effects of a branched-chain amino acid drink in mania

P. Cowen, C. Harmer, G. Goodwin, 2003, British Journal of Psychiatry.

Wake-up call for British psychiatry

Klaus P. Ebmeier, N. Craddock, A. Bailey, 2008, British Journal of Psychiatry.

Low Serum Cholesterol and Suicide

P. Cowen, A. Bond, K. Hawton, 1993, British Journal of Psychiatry.

Suicide and deliberate self-harm

Paul J. Harrison, P. Cowen, T. Burns, 2012 .

Ritanserin attenuates anorectic, endocrine and thermic responses tod-fenfluramine in human volunteers

P. Cowen, T. Silverstone, M. Franklin, 2005, Psychopharmacology.

Enhanced 5-hydroxytryptamine and dopamine-mediated behavioural responses following convulsions—II the effects of anaesthesia and current conditions on the appearance of enhanced responses following electroconvulsive shock

P. Cowen, D. Nutt, A. Green, 1980, Neuropharmacology.

Effect of venlafaxine on pineal melatonin and noradrenaline in the male rat

P. Cowen, M. Franklin, E. M. Clement, 1998, Journal of psychopharmacology.

Clomipramine enhances prolactin and growth hormone responses to l-tryptophan

P. Cowen, I. Anderson, 1986, Psychopharmacology.

Dieting reduces plasma tryptophan and alters brain 5-HT function in women

P. Cowen, I. Anderson, C. Fairburn, 1990, Psychological Medicine.

Decreased tryptophan availability but normal post-synaptic 5-HT2c receptor sensitivity in chronic fatigue syndrome

P. Cowen, L. Castell, A. Sharpley, 2001, Psychological Medicine.

Ondansetron and alcohol pharmacokinetics

P. Cowen, B. Johnson, J. Rue, 1993, Psychopharmacology.

The influence of comorbid depression and overweight status on peripheral inflammation and cortisol levels

E. Bullmore, P. Cowen, C. Pariante, 2021, Psychological Medicine.

Statins in Depression: An Evidence-Based Overview of Mechanisms and Clinical Studies

P. Cowen, C. Harmer, F. De Crescenzo, 2021, Frontiers in Psychiatry.

Lithium and 5-HT1A receptor sensitivity: a neuroendocrine study in healthy volunteers

P. Cowen, A. Walsh, C. J. Ware, 2005, Psychopharmacology.

Antidopaminergic effects of dietary tyrosine depletion in healthy subjects and patients with manic illness

P. Cowen, L. Clark, C. Harmer, 2001, British Journal of Psychiatry.

Plasma concentrations of tryptophan and dieting.

P. Cowen, G. Goodwin, C. Fairburn, 1990, BMJ.

Pharmacological management of treatment-resistant depression

P. Cowen, 1998 .

Lithium increases 5-HT-mediated prolactin release

Philip R. Cohen, P. Cowen, S. McCance, 2004, Psychopharmacology.

Lithium increases 5-HT-mediated neuroendocrine responses in tricyclic resistant depression

Philip R. Cohen, P. Cowen, D. Julier, 2004, Psychopharmacology.

The effect of lithium on 5-HT-mediated neuroendocrine responses and platelet 5-HT receptors

P. Cowen, D. Nutt, P. Glue, 2004, Psychopharmacology.

Depression resistant to tricyclic antidepressants.

P. Cowen, 1988, BMJ.

Dieting and weight loss in volunteers increases the number of alpha 2-adrenoceptors and 5-HT receptors on blood platelets without effect on [3H]imipramine binding.

P. Cowen, G. Goodwin, C. Fairburn, 1987, Journal of affective disorders.

Binding of yohimbine and imipramine to platelets in depressive illness

P. Cowen, L. Braddock, J. Elliott, 1986, Psychological Medicine.

Stress, inflammation and hippocampal subfields in depression: A 7 Tesla MRI Study

P. Cowen, J. Soares, S. Selvaraj, 2020, Translational Psychiatry.

Acute fluoxetine modulates emotional processing in young adult volunteers

P. Cowen, C. Harmer, M. Browning, 2015, Psychological Medicine.

Polymorphism of the 5-HT transporter and response to antidepressants: randomised controlled trial

T. Peters, D. Grozeva, N. Craddock, 2011, British Journal of Psychiatry.

Covariation of Activity in Habenula and Dorsal Raphé Nuclei Following Tryptophan Depletion

Karl J. Friston, R. J. Dolan, K. J. Friston, 1999, NeuroImage.

Alcohol‐induced reinforcement: Dopamine and 5‐HT3 receptor interactions in animals and humans

P. Cowen, B. Johnson, 1993 .

The effect of the serotonin transporter polymorphism (5-HTTLPR) on amygdala function: a meta-analysis

P. Cowen, M. Munafo, C. Harmer, 2013, Molecular Psychiatry.

Olanzapine increases slow-wave sleep: evidence for blockade of central 5-HT2C receptors in vivo

P. Cowen, A. Sharpley, C. Vassallo, 2000, Biological Psychiatry.

6.06 – Psychopharmacology

P. Cowen, 1998 .

Do authors know who refereed their paper? A questionnaire survey

P. Cowen, T. Brugha, S. Wessely, 1996, BMJ.

Toxic psychosis with antihistamines reversed by physostigmine.

P. Cowen, 1979, Postgraduate medical journal.

Impaired regulation of brain serotonin function during dieting in women recovered from depression

P. Cowen, K. Smith, C. Williams, 2000, British Journal of Psychiatry.

Does ondansetron attenuate amphetamine-induced behaviour in human volunteers?

P. Cowen, P. Silverstone, B. Johnson, 2005, Psychopharmacology.

NK1 receptor antagonism and the neural processing of emotional information in healthy volunteers.

P. Cowen, C. Harmer, C. McCabe, 2009, The international journal of neuropsychopharmacology.

The knowns and unknowns of SSRI treatment in young people with depression and anxiety: efficacy, predictors, and mechanisms of action.

P. Cowen, C. Harmer, A. Stringaris, 2021, The lancet. Psychiatry.

Increased 5-HT(2A) receptor binding in euthymic, medication-free patients recovered from depression: a positron emission study with [(11)C]MDL 100,907.

Zubin Bhagwagar, Rainer Hinz, P. Cowen, 2006, The American journal of psychiatry.

Effects of MDL 73005EF on central pre- and postsynaptic 5-HT1A receptor function in the rat in vivo.

P. Cowen, S. Hjorth, S. E. Gartside, 1990, European journal of pharmacology.

Risperidone augmentation decreases rapid eye movement sleep and decreases wake in treatment-resistant depressed patients.

P. Cowen, Z. Bhagwagar, H. Gijsman, 2003, The Journal of clinical psychiatry.

The role of serotonin in cognitive function: evidence from recent studies and implications for understanding depression

P. Cowen, A. C. Sherwood, 2013, Journal of psychopharmacology.

Increased neural response to fear in patients recovered from depression: a 3T functional magnetic resonance imaging study

P. Cowen, C. Harmer, S. Selvaraj, 2009, Psychological Medicine.

Effects of α-lactalbumin on emotional processing in healthy women

P. Cowen, C. Harmer, Anne Carbonnier, 2007 .

Effects of alpha-lactalbumin on emotional processing in healthy women.

P. Cowen, C. Harmer, Anne Carbonnier, 2007, Journal of psychopharmacology.

Severity of depression and response to antidepressants: GENPOD randomised controlled trial

T. Peters, P. Cowen, D. Nutt, 2012, British Journal of Psychiatry.

A role for 5-HT in the action of antidepressant drugs.

P. Cowen, P J Cowen, P. J. Cowen, 1990, Pharmacology & therapeutics.

Effect of pindolol on the prolactin response tod-denfluramine

P. Cowen, S. B. Park, 1995, Psychopharmacology.

Attenuation of some alcohol-induced mood changes and the desire to drink by 5-HT3 receptor blockade: a preliminary study in healthy male volunteers

P. Cowen, P. Griffiths, B. Johnson, 2005, Psychopharmacology.

Diazepam alters brain 5-HT function in man: implications for the acute and chronic effects of benzodiazepines

P. Cowen, D. Nutt, 1987, Psychological Medicine.

5-HT neuroendocrine function in major depression: prolactin and cortisol responses to D-fenfluramine

P. Cowen, S. B. Park, D. Williamson, 1996, Psychological Medicine.

Selective 5-HT1A and 5-HT2 receptor-mediated adrenocorticotropin release in the rat: effect of repeated antidepressant treatments.

P. Cowen, S. E. Gartside, T. Sharp, 1992, European journal of pharmacology.

Neuroendocrine markers of depression and antidepressant drug action

P. Cowen, 2001 .

Optimal dose of selective serotonin reuptake inhibitors, venlafaxine, and mirtazapine in major depression: a systematic review and dose-response meta-analysis

P. Cowen, M. Egger, T. Furukawa, 2019, The lancet. Psychiatry.

Title Optimal dose of selective serotonin reuptake inhibitors , venlafaxine , and mirtazapine in major depression : a systematic review and dose-response meta-analysis

P. Cowen, M. Egger, S. Leucht, 2019 .

Antidepressants, withdrawal, and addiction; where are we now?

P. Cowen, D. Nutt, G. Goodwin, 2019, Journal of psychopharmacology.

Trends and variation in antidepressant prescribing in English primary care: a retrospective longitudinal study

P. Cowen, A. Walker, H. Curtis, 2021, BJGP open.

Whole-blood expression of inflammasome- and glucocorticoid-related mRNAs correctly separates treatment-resistant depressed patients from drug-free and responsive patients in the BIODEP study

E. Bullmore, P. Cowen, W. Drevets, 2020, Translational Psychiatry.

New drugs, old problems: Revisiting... Pharmacological management of treatment-resistant depression

P. Cowen, 2005 .

Drug Treatment of Tricyclic Resistant Depression

P. Cowen, J. S. Chalmers, 1990 .

Neuroendocrine challenge tests: assessment of 5-HT function in anxiety and depression.

P. Cowen, A. C. Power, P. J. Cowen, 1992, Molecular aspects of medicine.

Persistent reduction in brain serotonin1A receptor binding in recovered depressed men measured by positron emission tomography with [11C]WAY-100635

P A Sargent, P. Cowen, P. Grasby, 2004, Molecular Psychiatry.

Effect of amitriptyline on endocrine responses to intravenous L-trytophan

P. Cowen, M. Gelder, D. Grahame-Smith, 1990, Psychiatry Research.

Electrophysiological and neurochemical evidence that pindolol has agonist properties at the 5‐HT1A autoreceptor in vivo

P. Cowen, M. Hajós, S. E. Gartside, 1998, British journal of pharmacology.

Dieting decreases plasma tryptophan and increases the prolactin response to d-fenfluramine in women but not men.

P. Cowen, C. Fairburn, M. Franklin, 1995, Journal of affective disorders.

Short-term SSRI treatment normalises amygdala hyperactivity in depressed patients

P. Cowen, C. Harmer, B. Godlewska, 2012, Psychological Medicine.

Reduction in Occipital Cortex γ-Aminobutyric Acid Concentrations in Medication-Free Recovered Unipolar Depressed and Bipolar Subjects

P. Matthews, P. Cowen, P. Jezzard, 2007, Biological Psychiatry.

Validation of a Tracer Kinetic Model for the Quantification of 5-HT2A Receptors in Human Brain with [11C]MDL 100,907

Vincent J Cunningham, Zubin Bhagwagar, Rainer Hinz, 2007, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

5-HT2C receptor activation decreases appetite and body weight in obese subjects

P. Cowen, A. Sharpley, P. Sargent, 1997, Psychopharmacology.

Melatonin as a treatment for mood disorders: a systematic review

P. Cowen, D. Quested, S. Stockton, 2017, Acta psychiatrica Scandinavica.

Tianeptine in an experimental medicine model of antidepressant action

P. Cowen, C. Harmer, D. Whiting, 2015, Journal of psychopharmacology.

Effects of Short-Term Varenicline Administration on Emotional and Cognitive Processing in Healthy, Non-Smoking Adults: A Randomized, Double-Blind, Study

P. Cowen, C. Harmer, R. Mocking, 2013, Neuropsychopharmacology.

Effects of 7 days of treatment with the cannabinoid type 1 receptor antagonist, rimonabant, on emotional processing

P. Cowen, C. Harmer, M. Browning, 2012, Journal of psychopharmacology.

Acute administration of the cannabinoid CB1 antagonist rimonabant impairs positive affective memory in healthy volunteers

P. Cowen, C. Harmer, M. Browning, 2009, Psychopharmacology.

Probing the Function of 5-HT1B/1D Receptors in Psychiatric Patients

P. Cowen, R. Whale, 1998, CNS Spectrums.

Decision making in young people at familial risk of depression

P. Cowen, M. Browning, Z. Mannie, 2014, Psychological Medicine.

Allowing for non-adherence to treatment in a randomized controlled trial of two antidepressants (citalopram versus reboxetine): an example from the GENPOD trial

T. Peters, P. Cowen, I. White, 2014, Psychological Medicine.

Impairments in working memory associated with naturalistic dieting in women: no relationship between task performance and urinary 5-HIAA levels

P. Cowen, P. Durlach, H. Healy, 2003, Appetite.

Childhood trauma, HPA axis activity and antidepressant response in patients with depression

E. Bullmore, P. Cowen, C. Pariante, 2019, Brain, Behavior, and Immunity.

GENetic and clinical Predictors Of treatment response in Depression: the GenPod randomised trial protocol

T. Peters, P. Cowen, D. Nutt, 2008, Trials.

S0033291721000088jra 3289..3296

E. Bullmore, P. Cowen, C. Pariante, 2022 .

Effects of typhoid vaccine on inflammation and sleep in healthy participants: a double-blind, placebo-controlled, crossover study

P. Cowen, B. Godlewska, A. Sharpley, 2016, Psychopharmacology.

Lithium Prescribing during Pregnancy: A UK Primary Care Database Study

P. Cowen, I. Petersen, I. Nazareth, 2014, PloS one.

The Role of Serotonin in Nonnormative Risky Choice: The Effects of Tryptophan Supplements on the “Reflection Effect” in Healthy Adult Volunteers

Catherine J. Harmer, Robert D. Rogers, Susannah E. Murphy, 2009, Journal of Cognitive Neuroscience.

Comparative efficacy and acceptability of pharmacological treatments for post-traumatic stress disorder in adults: a network meta-analysis

Dan J Stein, P. Cowen, J. Geddes, 2017, Psychological Medicine.

Measuring endogenous changes in serotonergic neurotransmission in humans: a [11C]CUMI-101 PET challenge study

F. Turkheimer, P. Cowen, J. Roiser, 2012, Molecular Psychiatry.

Fifty years on: Serotonin and depression

P. Cowen, M. Browning, S. Jauhar, 2023, Journal of psychopharmacology.

Low-dose citalopram as a 5-HT neuroendocrine probe

P. Cowen, T. Terao, M. Attenburrow, 2001, Psychopharmacology.

Effects of (−)‐tertatolol, (−)‐penbutolol and (±)‐pindolol in combination with paroxetine on presynaptic 5‐HT function: an in vivo microdialysis and electrophysiological study

P. Cowen, T. Sharp, S E Gartside, 1999, British journal of pharmacology.

Serotonin Receptor Subtypes: Implications for Psychopharmacology

P. Cowen, P J Cowen, 1991, British Journal of Psychiatry.

Folic acid supplementation for prevention of mood disorders in young people at familial risk: a randomised, double blind, placebo controlled trial.

P. Cowen, J. Geddes, A. Sharpley, 2014, Journal of affective disorders.

OF TREATMENT-RESISTANT DEPRESSION

P. Cowen, 2005 .

L-tryptophan and the eosinophilia-myalgia syndrome

P. Cowen, 1990 .

Selective serotonin reuptake inhibitors Drugs related to tricyclic antidepressants are a mixed bag

P. Cowen, C. Thompson, 1994, BMJ.

5-HT(1A) receptor binding in euthymic bipolar patients using positron emission tomography with [carbonyl-(11)C]WAY-100635.

P. Cowen, L. Clark, P. Grasby, 2010, Journal of affective disorders.

Antidepressant-like effect of Hypericum perforatum (St John’s wort) on the sleep polysomnogram

P. Cowen, A. Sharpley, R. Whale, 1998, Psychopharmacology.

Increased brain GABA concentrations following acute administration of a selective serotonin reuptake inhibitor.

P. Matthews, P. Cowen, P. Jezzard, 2004, The American journal of psychiatry.

Dieting changes serotonergic function in women, not men: implications for the aetiology of anorexia nervosa?

P. Cowen, G. Goodwin, C. Fairburn, 1987, Psychological Medicine.

Predicting Treatment Response in Depression: The Role of Anterior Cingulate Cortex

P. Cowen, C. Harmer, M. Browning, 2018, The international journal of neuropsychopharmacology.

Fronto-limbic effective connectivity as possible predictor of antidepressant response to SSRI administration

Catherine J. Harmer, Chiara Bulgarelli, Philip J. Cowen, 2016, European Neuropsychopharmacology.

Serotonin, depression and antidepressant action

P. Cowen, 2013 .

Comparison of the Effects of Citalopram and Escitalopram on 5-Ht-Mediated Neuroendocrine Responses

P. Cowen, M. Attenburrow, Haitham Nadeem, 2004, Neuropsychopharmacology.

No benefit from flexible titration above minimum licensed dose in prescribing antidepressants for major depression: systematic review

P. Cowen, T. Furukawa, S. Leucht, 2019, Acta psychiatrica Scandinavica.

Comparative efficacy and acceptability of pharmacological treatments for post-traumatic stress disorder in adults: a network meta-analysis

Dan J Stein, P. Cowen, J. Geddes, 2017, Psychological Medicine.

Unedited in vivo detection and quantification of γ‐aminobutyric acid in the occipital cortex using short‐TE MRS at 3 T

Rolf Gruetter, Peter Jezzard, Jamie Near, 2013, NMR in biomedicine.

Serotonin receptor subtypes in depression: evidence from studies in neuroendocrine regulation.

P. Cowen, 1993, Clinical neuropharmacology.

Prolactin response to tryptophan during mianserin treatment.

P. Cowen, 1988, The American journal of psychiatry.

A single administration of the antibiotic, minocycline, reduces fear processing and improves implicit learning in healthy volunteers: analysis of the serum metabolome

P. Cowen, C. Harmer, D. Anthony, 2020, Translational Psychiatry.

Negative ion treatment increases positive emotional processing in seasonal affective disorder

P. Cowen, C. Harmer, E. Favaron, 2011, Psychological Medicine.

S.07.03 Short-term SSRI treatment remediates amygdala hyperactivity in depressed patients

P. Cowen, C. Harmer, B. Godlewska, 2011, European Neuropsychopharmacology.

Agomelatine facilitates positive versus negative affective processing in healthy volunteer models

G. Dawson, P. Cowen, C. Harmer, 2011, Journal of psychopharmacology.

A cognitive neuropsychological model of antidepressant drug action

P. Cowen, M. Browning, A. Pringle, 2011, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

neuropsychological model of antidepressant drug action Why do antidepressants take so long to work ? A cognitive

P. Cowen, C. Harmer, G. Goodwin, 2009 .

Dissociable effects of acute antidepressant drug administration on subjective and emotional processing measures in healthy volunteers

P. Cowen, C. Harmer, U. O’Sullivan, 2008, Psychopharmacology.

Emotional bias and waking salivary cortisol in relatives of patients with major depression

P. Cowen, C. Harmer, M. Le Masurier, 2006, Psychological Medicine.

Tryptophan supplementation induces a positive bias in the processing of emotional material in healthy female volunteers

Catherine J. Harmer, Susannah E. Murphy, Philip J. Cowen, 2006, Psychopharmacology.

Administration of the beta-adrenoceptor blocker propranolol impairs the processing of facial expressions of sadness

D. Perrett, P. Cowen, C. Harmer, 2001, Psychopharmacology.

Serotonin revisited

P. Cowen, I. Lucki, 2010, Psychopharmacology.

Ethyl β-carboline carboxylate lowers seizure threshold and antagonizes flurazepam-induced sedation in rats

P. Cowen, D. Nutt, I. Martin, 1981, Nature.

Attenuation of the Prolactin‐Stimulating and Hyperthermic Effects of Nefazodone After Subacute Treatment

P. Cowen, Frcpsych, A. Walsh, 1994, Journal of clinical psychopharmacology.

Monoamine function in anxiety and depression: Information from neuroendocrine challenge tests

P. Cowen, D. Nutt, 1987 .

No antidepressant-like acute effects of bright light on emotional information processing in healthy volunteers

P. Cowen, C. Harmer, T. Zghoul, 2021, Psychopharmacology.

Translating the promise of 5HT4 receptor agonists for the treatment of depression

P. Cowen, C. Harmer, B. Godlewska, 2020, Psychological Medicine.

The putative lithium-mimetic ebselen reduces impulsivity in rodent models

Wendy K. Adams, P. Cowen, R. Rogers, 2018, Journal of psychopharmacology.

5HT3 antagonism abolishes the emotion potentiated startle effect in humans

P. Cowen, C. Harmer, G. Goodwin, 2006, Psychopharmacology.

Platelet 5-HT receptor binding during depressive illness and tricyclic antidepressant treatment.

P. Cowen, J. Elliott, S. Fraser, 1987, Journal of affective disorders.

The effects of paroxetine and nefazodone on sleep: a placebo controlled trial

P. Cowen, M. Attenburrow, A. Sharpley, 1996, Psychopharmacology.

Effect of paroxetine and nefazodone on 5-HT1A receptor sensitivity

P. Cowen, P. Sargent, D. Williamson, 1997, Psychopharmacology.

Serotonin and depression: pathophysiological mechanism or marketing myth?

P. Cowen, 2008, Trends in pharmacological sciences.

6: Cholesterol-lowering drugs, brain serotonin function and violent death: three phenomena in search of a hypothesis

P. Cowen, 1992 .

Pharmacotherapy for anxiety disorders: drugs available

P. Cowen, 1997 .

Subchronic treatment with St John’s wort produces a positive shift in emotional processing in healthy volunteers

P. Cowen, C. Harmer, M. Warren, 2018, Journal of psychopharmacology.

Evaluation of first night effect using ambulatory monitoring and automatic sleep stage analysis.

P. Cowen, A. Sharpley, P J Cowen, 1988, Sleep.

Reduced neural response to reward following 7 days treatment with the cannabinoid CB1 antagonist rimonabant in healthy volunteers.

P. Cowen, C. Harmer, C. McCabe, 2010, The international journal of neuropsychopharmacology.

Direct effects of diazepam on emotional processing in healthy volunteers

P. Cowen, C. Harmer, S. Murphy, 2007, Psychopharmacology.

Depression, violence and cortisol awakening response: a 3-year longitudinal study in adolescents

P. Cowen, S. Branje, W. Meeus, 2018, Psychological Medicine.

Differential effects of clonidine, haloperidol, diazepam and tryptophan depletion on focused attention and attentional search

T. Robbins, A. Young, P. Cowen, 1995, Psychopharmacology.

Cardiovascular and metabolic risk profile in young people at familial risk of depression

P. Cowen, A. Steptoe, P. Leeson, 2013, British Journal of Psychiatry.

Initial Studies in Man to Characterise MDL 73,005EF, a Novel 5-HT1A Receptor Ligand and Putative Anxiolytic

P. Cowen, K. Haegele, M. Boyce, 1991 .

Slow wave sleep in humans: Role of 5-HT2A and 5-HT2C receptors

P. Cowen, M. Attenburrow, A. Sharpley, 1994, Neuropharmacology.

Paroxetine treatment and the prolactin response to sumatriptan

P. Cowen, Y. Wing, E. M. Clifford, 1996, Psychopharmacology.

5-HTT binding in recovered depressed patients and healthy volunteers: a positron emission tomography study with [11C]DASB.

P. Cowen, P. Grasby, Z. Bhagwagar, 2007, The American journal of psychiatry.

Serotonin transporter polymorphisms (SLC6A4 insertion/deletion and rs25531) do not affect the availability of 5-HTT to [11C] DASB binding in the living human brain

Marc Laruelle, Barbara J. Sahakian, Eugenii A. Rabiner, 2010, NeuroImage.

Effect of castration and castration with hormone replacement on the plasma prolactin responses to neuroendocrine challenge with i.v. mCPP in the male rat following a low tryptophan diet

P. Cowen, M. Franklin, R. Craven, 1996, Journal of psychopharmacology.

Brain 5-HT function in obsessive-compulsive disorder

P. Cowen, N. Fineberg, S. Montgomery, 1997, British Journal of Psychiatry.

State and trait abnormalities in serotonin function in major depression

P. Cowen, Z. Bhagwagar, R. Whale, 2002, British Journal of Psychiatry.

The effects of chronic ritanserin treatment on sleep and the neuroendocrine response to l-tryptophan

P. Cowen, D. Nutt, C. Idzikowski, 2004, Psychopharmacology.

Effect of central cholinergic stimulation on regional cerebral blood flow in Alzheimer disease

B. J. Shepstone, P. Cowen, B. Shepstone, 1990, The Lancet.

Ketamine infusions for treatment resistant depression: a series of 28 patients treated weekly or twice weekly in an ECT clinic

John R Geddes, P. Cowen, J. Geddes, 2014, Journal of psychopharmacology.

Lack of effect of ketamine on cortical glutamate and glutamine in healthy volunteers: a proton magnetic resonance spectroscopy study

P. Cowen, R. Mhuircheartaigh, E. Tiangga, 2012, Journal of psychopharmacology.

Beta adrenergic blockade reduces utilitarian judgement

P. Cowen, Terbeck Sylvia, Kahane Guy, 2013, Biological Psychology.

A Database of [11C]WAY-100635 Binding to 5-HT1A Receptors in Normal Male Volunteers: Normative Data and Relationship to Methodological, Demographic, Physiological, and Behavioral Variables

Roger N. Gunn, Peter A. Sargent, Christopher J. Bench, 2002, NeuroImage.

Effect of a tyrosine-free amino acid mixture on regional brain catecholamine synthesis and release

Philip J. Cowen, P. Cowen, T. Sharp, 1999, Psychopharmacology.

Propranolol reduces implicit negative racial bias

P. Cowen, J. Savulescu, M. Hewstone, 2012, Psychopharmacology.

Elevated cortical glutamate in young people at increased familial risk of depression.

P. Cowen, J. Near, R. Norbury, 2011, The international journal of neuropsychopharmacology.

Electrochemical Detection and Quantification of Lithium Ions in Authentic Human Saliva Using LiMn2O4-modified Electrodes.

P. Cowen, B. Godlewska, R. Compton, 2019, ACS sensors.

Neurochemical abnormalities in chronic fatigue syndrome: a pilot magnetic resonance spectroscopy study at 7 Tesla

Ana Jorge Gonçalves, William T. Clarke, P. Cowen, 2021, Psychopharmacology.

Ketamine and other glutamate receptor modulators for depression in adults with bipolar disorder.

P. Cowen, A. Cipriani, G. Malhi, 2021, The Cochrane database of systematic reviews.

A phase 2a randomised, double-blind, placebo-controlled, parallel-group, add-on clinical trial of ebselen (SPI-1005) as a novel treatment for mania or hypomania

P. Cowen, B. Godlewska, M. Shanyinde, 2020, Psychopharmacology.

Pindolol augmentation of selective serotonin reuptake inhibitors: PET evidence that the dose used in clinical trials is too low.

P. Cowen, P. Grasby, C. Bench, 2001, The American journal of psychiatry.

Emotional face processing in women with high and low levels of eating disorder related symptoms.

P. Cowen, C. Harmer, M. Cooper, 2008, Eating behaviors.

The effects of atorvastatin on emotional processing, reward learning, verbal memory and inflammation in healthy volunteers: An experimental medicine study

P. Cowen, C. Harmer, M. Martens, 2021, Journal of psychopharmacology.

Effects of various statins on depressive symptoms: is there enough evidence?

P. Cowen, F. De Crescenzo, R. De Giorgi, 2021, Journal of affective disorders.

Neurochemistry of major depression: a study using magnetic resonance spectroscopy

Jamie Near, Philip J. Cowen, Beata R. Godlewska, 2014, Psychopharmacology.

Cortical glutathione levels in young people with bipolar disorder: a pilot study using magnetic resonance spectroscopy

P. Cowen, G. Goodwin, B. Godlewska, 2013, Psychopharmacology.

Neural effects of a single dose of fluoxetine on resting-state functional connectivity in adolescent depression

P. Cowen, A. James, N. Filippini, 2020, Journal of psychopharmacology.

Effects of seven-day diazepam administration on resting-state functional connectivity in healthy volunteers: a randomized, double-blind study

Catherine J. Harmer, Nicola Filippini, P. Cowen, 2014, Psychopharmacology.

5-HT1A receptor density and defensive personality - interaction of neurochemistry, personality and depression explored with [11C]WAY 100635 PET

P. Cowen, A. Lawrence, P. Grasby, 2005 .

An Experimental Medicine Investigation of the Effects of Subacute Pramipexole Treatment on Emotional Information Processing in Healthy Volunteers

P. Cowen, C. Harmer, M. Browning, 2021, Pharmaceuticals.

Backing into the future: pharmacological approaches to the management of resistant depression

P. Cowen, PJ Cowen, 2017, Psychological Medicine.

Further evidence for a relationship between changes in GABA concentration in rat brain and enhanced monoamine-mediated behavioural responses following repeated electroconvulsive shock

P. Cowen, J. Bowdler, A. Green, 1982, Neuropharmacology.

ELECTROCONVULSIVE THERAPY AND THE BRAIN: EVIDENCE FOR INCREASED DOPAMINE-MEDIATED RESPONSES

P. Cowen, M. Gelder, D. Grahame-Smith, 1982, The Lancet.

Mechanism of Action of ECT

P. Cowen, 2019, The ECT Handbook.

A Functional Magnetic Resonance Imaging Study of Verbal Working Memory in Young People at Increased Familial Risk of Depression

P. Cowen, C. Harmer, R. Norbury, 2010, Biological Psychiatry.

Neural response to angry and disgusted facial expressions in bulimia nervosa

P. Cowen, C. Harmer, M. Cooper, 2011, Psychological Medicine.

A single dose of mirtazapine modulates neural responses to emotional faces in healthy people

P. Cowen, C. Harmer, N. Rawlings, 2010, Psychopharmacology.

Using Attentional Bias Modification as a Cognitive Vaccine Against Depression

E. Holmes, P. Cowen, C. Harmer, 2012, Biological Psychiatry.

Revisiting monoamine oxidase inhibitors for the treatment of depressive disorders: A systematic review and network meta-analysis.

P. Cowen, J. Soares, S. Selvaraj, 2021, Journal of affective disorders.

An online experimental medicine trial on the effect of 28-day simvastatin administration on emotional processing, reward learning, working memory and salivary cortisol in healthy volunteers at risk for depression: OxSTEP protocol

P. Cowen, C. Harmer, S. Murphy, 2023, BJPsych Open.

Interferon-α induces negative biases in emotional processing in patients with hepatitis C virus infection: a preliminary study

P. Cowen, C. Harmer, E. Barnes, 2017, Psychological Medicine.

Cognitive mechanisms of diazepam administration: a healthy volunteer model of emotional processing

P. Cowen, A. Pringle, C. Harmer, 2016, Psychopharmacology.

Short-term NK1 receptor antagonism and emotional processing in healthy volunteers

P. Cowen, C. Harmer, S. Mctavish, 2011, Psychopharmacology.

Negative Self-Beliefs in Relation to Eating Disorder and Depressive Symptoms: Different Themes Are Characteristic of the Two Sets of Symptoms in Those With Eating Disorders and/or Depression

P. Cowen, M. Cooper, 2009, Journal of Cognitive Psychotherapy.

Early effects of mirtazapine on emotional processing

P. Cowen, C. Harmer, D. Arnone, 2009, Psychopharmacology.

The effects of reboxetine on emotional processing in healthy volunteers: an fMRI study

P. Cowen, C. Harmer, G. Goodwin, 2008, Molecular Psychiatry.

Impaired emotional categorisation in young people at increased familial risk of depression

P. Cowen, C. Harmer, Z. Mannie, 2007, Neuropsychologia.

Toward a neuropsychological theory of antidepressant drug action: increase in positive emotional bias after potentiation of norepinephrine activity.

P. Cowen, C. Harmer, G. Goodwin, 2003, The American journal of psychiatry.

Effect of short-term escitalopram treatment on neural activation during emotional processing

P. Matthews, P. Cowen, D. Nutt, 2016, Journal of psychopharmacology.

Serotonin transporter (5-HTT) promoter genotype may influence the prolactin response to clomipramine

Paul J. Harrison, P. J. Harrison, P. Cowen, 2000, Psychopharmacology.

A translational perspective on the anti-anhedonic effect of ketamine and its neural underpinnings

P. Cowen, C. Harmer, S. Murphy, 2021, Molecular Psychiatry.

m-Chlorophenylpiperazine decreases food intake in a test meal

P. Cowen, K. Smith, C. Williams, 1994, Psychopharmacology.

Brain 5-HT neurotransmission during paroxetine treatment

P. Cowen, P. Sargent, D. Williamson, 1998, British Journal of Psychiatry.

Neurochemistry of major depression: a study using magnetic resonance spectroscopy

P. Cowen, B. Godlewska, J. Near, 2014, Psychopharmacology.

Cortical glutathione levels in young people with bipolar disorder: a pilot study using magnetic resonance spectroscopy

P. Cowen, G. Goodwin, B. Godlewska, 2013, Psychopharmacology.

Efficient γ‐aminobutyric acid editing at 3T without macromolecule contamination: MEGA‐SPECIAL

Peter Jezzard, Jamie Near, Robin Simpson, 2011, NMR in biomedicine.

Slow, repetitive transcranial magnetic stimulation was effective for major depression

P. Cowen, 1999 .

Early increase in marker of neuronal integrity with antidepressant treatment of major depression: 1H-magnetic resonance spectroscopy of N-acetyl-aspartate

P. Cowen, S. Selvaraj, B. Godlewska, 2012, The international journal of neuropsychopharmacology.

Ultra-High-Field Magnetic Resonance Spectroscopy in Psychiatry

Uzay E. Emir, Stuart Clare, Philip J. Cowen, 2017, Front. Psychiatry.

Salivary glutathione in bipolar disorder: A pilot study.

P. Cowen, B. Godlewska, R. Compton, 2018, Journal of affective disorders.

Decreased plasma tryptophan concentration in major depression: relationship to melancholia and weight loss.

P. Cowen, I. Anderson, E. Newsholme, 1990, Journal of affective disorders.

The effects of a branched chain amino acid mixture supplemented with tryptophan on biochemical indices of neurotransmitter function and decision-making

P. Cowen, R. Rogers, G. Goodwin, 2005, Psychopharmacology.

Effect of Tryptophan Depletion on Mood in Male and Female Volunteers: A Pilot Study

P. Cowen, K. Smith, D. Clark, 1997 .

The effects of a low tryptophan diet on brain 5 -HT metabolism and 5-HT-mediated neuroendocrine responses in the male rat

P. Cowen, M. Franklin, R. Craven, 1995, Journal of psychopharmacology.

Effect of acute tryptophan depletion on mood and appetite in healthy female volunteers

P. Salkovskis, P. Cowen, D. Oldman, 1994, Journal of psychopharmacology.

Biochemical and behavioural effects of acute tryptophan depletion in abstinent bulimic subjects: a pilot study

P. Salkovskis, P. Cowen, C. Fairburn, 1995, Psychological Medicine.

Moderate dieting causes 5-HT 2C receptor supersensitivity

P. Cowen, C. Fairburn, E. M. Clifford, 1996, Psychological Medicine.

Decreased regional gray matter volume in S’ allele carriers of the 5-HTTLPR triallelic polymorphism

F. Turkheimer, P. Cowen, O. Howes, 2011, Molecular Psychiatry.

S0033291720001221jra 2657..2665

P. Cowen, C. Harmer, Runsen Chen, 2021 .

Short-term serotonergic but not noradrenergic antidepressant administration reduces attentional vigilance to threat in healthy volunteers.

P. Cowen, C. Harmer, J. Yiend, 2009, The international journal of neuropsychopharmacology.

Effects of the potential lithium-mimetic, ebselen, on impulsivity and emotional processing

P. Cowen, R. Rogers, C. Harmer, 2016, Psychopharmacology.

Modelling a loss event: effect of imagined bereavement on the hypothalamic–pituitary–adrenal axis

P. Cowen, G. Goodwin, Z. Bhagwagar, 2000, Psychological Medicine.

Effect of a long-term low tryptophan diet on the prolactin responses to the 5-HT1A and 5-HT2C agonists, 8-OH-DPAT and mCPP in the male rat

P. Cowen, B. Dowling, M. Franklin, 1999, Journal of psychopharmacology.

Use of a dietary manipulation to deplete plasma tyrosine and phenylalanine in healthy subjects

P. Cowen, G. Campling, B. Sheehan, 1996, Journal of psychopharmacology.

The effects of dieting and weight loss on neuroendocrine responses to tryptophan, clonidine, and apomorphine in volunteers. Important implications for neuroendocrine investigations in depression.

P. Cowen, G. Goodwin, C. Fairburn, 1987, Archives of general psychiatry.

Effects of acute tyrosine depletion on subjective craving and selective processing of smoking-related cues in abstinent cigarette smokers

P. Cowen, M. Munafo, C. Harmer, 2007, Journal of psychopharmacology.

Decreased plasma tryptophan levels in major depression.

P. Cowen, E. Newsholme, M. Parry-Billings, 1989, Journal of affective disorders.

Effect of the putative lithium mimetic ebselen on brain myo-inositol, sleep and emotional processing in humans

Uzay E Emir, Nisha Singh, Trevor Sharp, 2016, Neuropsychopharmacology.

GABA and mood disorders

P. Cowen, Z. Bhagwagar, T. Sharp, 2003, Psychological Medicine.

Blunted growth hormone and prolactin responses to L-tryptophan in depression; a state-dependent abnormality.

P. Cowen, J. Deakin, A. Upadhyaya, 1991, Journal of affective disorders.

Effects of erythropoietin on emotional processing biases in patients with major depression: an exploratory fMRI study

P. Cowen, C. Harmer, E. Favaron, 2009, Psychopharmacology.

Effects of the potential lithium-mimetic, ebselen, on impulsivity and emotional processing

P. Cowen, R. Rogers, C. Harmer, 2016, Psychopharmacology.

Imaging vulnerability for depression

P. Cowen, R. Norbury, Z. Mannie, 2011, Molecular Psychiatry.

The Effect of Apomorphine and Buspirone on Regional Cerebral Blood Flow During the Performance of a Cognitive Task—Measuring Neuromodulatory Effects of Psychotropic Drugs in Man

Karl J. Friston, R. Dolan, P. Cowen, 1992, The European journal of neuroscience.

Human 5-HT Transporter Availability Predicts Amygdala Reactivity In Vivo

M. Alex Dresner, Philip J. Cowen, Sudhakar Selvaraj, 2007, The Journal of Neuroscience.

A perspective: from the serotonin hypothesis to cognitive neuropsychological approaches

P. Cowen, C. Harmer, T. Zghoul, 2019, The Serotonin System.

Short-term antidepressant treatment and facial processing

Clare E Mackay, Ray Norbury, P. Cowen, 2007, British Journal of Psychiatry.

Serotonin, dieting, and bulimia nervosa.

P. Cowen, K. Smith, 1999, Advances in experimental medicine and biology.

Repetitive transcranial magnetic stimulation to right prefrontal cortex does not modulate the psychostimulant effects of amphetamine.

P. Cowen, L. Clark, C. Harmer, 2000, International Journal of Neuropsychopharmacology.

Simplified quantification of 5-HT2A receptors in the human brain with [11C]MDL 100,907 PET and non-invasive kinetic analyses

Rainer Hinz, Vincent J. Cunningham, Paul M. Grasby, 2010, NeuroImage.

Mood, eating behaviour and attention

P. Cowen, P. Durlach, J. Williams, 2002, Psychological Medicine.

Olanzapine increases slow wave sleep and sleep continuity in SSRI-resistant depressed patients.

P. Cowen, M. Attenburrow, A. Sharpley, 2005, The Journal of clinical psychiatry.

The effect of tryptophan on brain 5‐HT function: A review

P. Cowen, 1994 .

Serotonin, sleep and mental disorder

P. Cowen, C. Idzikowski, 1991 .

The neurotransmitter basis of cognition: psychopharmacological activation studies using positron emission tomography.

Karl J. Friston, K J Friston, C D Frith, 1991, Ciba Foundation symposium.

Brain serotonin transporter binding in former users of MDMA ('ecstasy').

P. Cowen, P. Grasby, Z. Bhagwagar, 2009, The British journal of psychiatry : the journal of mental science.

Lithium increases slow wave sleep: possible mediation by brain 5-HT2 receptors?

Karl J. Friston, P. Cowen, A. Sharpley, 1989, Psychopharmacology.

Lack of effect of oestradiol implant on platelet imipramine and 5-HT2 receptor binding in menopausal subjects

P. Cowen, D. Barlow, N. Best, 2004, Psychopharmacology.

Effect of interferon-α on cortical glutamate in patients with hepatitis C: a proton magnetic resonance spectroscopy study

P. Cowen, P. Klenerman, E. Barnes, 2013, Psychological Medicine.

EFFECT OF INTERFERON-α ON CORTICAL GLUTAMATE IN PATIENTS WITH HEPATITIS C : A PROTON MRS STUDY

P. Cowen, P. Klenerman, E. Barnes, 2013 .

The Effect of the 5-HT4 Agonist, Prucalopride, on a Functional Magnetic Resonance Imaging Faces Task in the Healthy Human Brain

P. Cowen, C. Harmer, S. Murphy, 2022, Frontiers in Psychiatry.

Déjà-vu? Neural and behavioural effects of the 5-HT4 receptor agonist, prucalopride, in a hippocampal-dependent memory task

P. Cowen, N. Filippini, C. Harmer, 2021, Translational Psychiatry.

A role for 5-HT4 receptors in human learning and memory

P. Cowen, C. Harmer, M. Browning, 2019, Psychological Medicine.

State and trait abnormalities in serotonin function in major depression.

P. Cowen, Z. Bhagwagar, R. Whale, 2002, The British journal of psychiatry : the journal of mental science.

Effects of pramipexole on the processing of rewarding and aversive taste stimuli

P. Cowen, C. Harmer, C. McCabe, 2013, Psychopharmacology.

Tyrosine‐free amino acid mixture attenuates amphetamine‐induced displacement of [11C]raclopride in striatum in vivo: A rat PET study

Susan Hume, Trevor Sharp, G. Houston, 2004, Synapse.

Clomipramine enhances the cortisol response to 5-HTP: implications for the therapeutic role of 5-HT2 receptors

P. Cowen, D. Quested, P. Sargent, 1998, Psychopharmacology.

Opposing neural effects of naltrexone on food reward and aversion: implications for the treatment of obesity

P. Cowen, C. Harmer, C. McCabe, 2014, Psychopharmacology.

Twin studies and the etiology of eating disorders.

Paul J. Harrison, P. Cowen, C. Fairburn, 1999, The International journal of eating disorders.

Enhanced early morning salivary cortisol in neuroticism.

P. Cowen, J. Flint, C. Harmer, 2005, The American journal of psychiatry.

Psychopharmacology of 5-HT(1A) receptors.

P. Cowen, 2000, Nuclear medicine and biology.

The effect of the dopamine agonist, apomorphine, on regional cerebral blood flow in normal volunteers

Karl J. Friston, K J Friston, C D Frith, 1993, Psychological Medicine.

Cortisol modulation of 5-HT-mediated growth hormone release in recovered depressed patients.

P. Cowen, Z. Bhagwagar, S. Hafizi, 2002, Journal of affective disorders.

Biochemical stress of caring

P. Cowen, J. M. da Roza Davis, P. Cowen, 2001, Psychological Medicine.

Pindolol decreases prolactin and growth hormone responses to intravenousL-tryptophan

P. Cowen, ClarenceE . Smith, C. J. Ware, 2005, Psychopharmacology.

Tyrosine depletion attenuates dopamine function in healthy volunteers

P. Cowen, L. Clark, C. Harmer, 2001, Psychopharmacology.

5HT‐3 receptor blockade in nicotine withdrawal: Study with BRL 46470A

P. Cowen, A. Smith, S. B. Park, 1993 .

Why is dieting so difficult?

P. Cowen, C. Fairburn, E. M. Clifford, 1995, Nature.

Constructionism

P. Cowen, 2011, British medical journal.

SCHIZOTYPY AND HEIGHT : REDUCED HEIGHT IN HIGH-SCHIZOTYPAL HEALTHY MEN

J. Rawlins, P. Cowen, J. Feldon, 1996 .

Prescribing for moderate or severe unipolar depression in patients under the long-term care of UK adult mental health services

P. Cowen, I. Anderson, T. Barnes, 2020, Therapeutic advances in psychopharmacology.

Effects of hydrocortisone on brain 5-HT function and sleep.

A. Young, P. Cowen, A. Sharpley, 1994, Journal of affective disorders.

The benzodiazepine antagonist, Ro 15-1788 does not decrease ethanol withdrawal convulsions in rats.

P. Cowen, D. Nutt, H. Little, 1985, European journal of pharmacology.

Using Ro 15-1788 to investigate the benzodiazepine receptor in vivo: Studies on the anticonvulsant and sedative effect of melatonin and the convulsant effect of the benzodiazepine Ro 05-3663

P. Cowen, D. Nutt, A. Green, 2004, Psychopharmacology.

A single dose of fluoxetine reduces neural limbic responses to anger in depressed adolescents

P. Cowen, A. James, C. Harmer, 2019, Translational Psychiatry.

Decreased 5-HT-Mediated Prolactin Release in Major Depression

P. Cowen, I. Anderson, J. M. da Roza Davis, 1992, British Journal of Psychiatry.

Prolactin response to the dopamine antagonist, metoclopramide, in depression

P. Cowen, I. Anderson, 1991, Biological Psychiatry.

Investigations of 5-HT Neuroendocrine Function in Depression

P. Cowen, I. Anderson, 1990 .

The effect of metergoline on endocrine responses to L-tryptophan

P. Cowen, D. Grahame-Smith, S. McCance, 1987, Journal of psychopharmacology.

Carriage of the S′ allele serotonin transporter polymorphisms (SLC6A4 insertion/deletion and rs25531) may influence brain morphology

F. Turkheimer, P. Cowen, O. Howes, 2011, Molecular Psychiatry.

Neurokinin-1 receptor antagonists as novel antidepressants: trials and tribulations

P. Cowen, S. Hafizi, P. Chandra, 2007, British Journal of Psychiatry.

Lack of effect of chromium supplementation on mental state and body weight in people with schizophrenia.

P. Cowen, J. Geddes, P. Montgomery, 2006, Journal of clinical psychopharmacology.

Neural Processing of Reward and Punishment in Young People at Increased Familial Risk of Depression

P. Cowen, C. Harmer, C. McCabe, 2012, Biological Psychiatry.

Optimal Dose of Selective Serotonin Reuptake Inhibitors, Venlafaxine, and Mirtazapine in Major Depression: A Systematic Review and Dose-Response Meta-Analysis.

P. Cowen, M. Egger, T. Furukawa, 2020, Focus.

The Serotonin 1A (5-HT_1A) Receptor as a Pharmacological Target in Depression

P. Cowen, C. Harmer, S. Murphy, 2023, CNS Drugs.

The Effect of Moderate Weight Loss on Overnight Melatonin Secretion

P. Cowen, I. Anderson, S. Gartside, 1990, British Journal of Psychiatry.

Repeated administration of subconvulsant doses of GABA antagonist drugs

P. Cowen, D. Nutt, D. Grahame-Smith, 2004, Psychopharmacology.

5-HT4 receptor agonist effects on functional connectivity in the human brain; Implications for pro-cognitive action.

P. Cowen, C. Harmer, S. Suri, 2023, Biological psychiatry. Cognitive neuroscience and neuroimaging.

Neuroendocrine Responses as a Probe into the Mechanisms of Action of Electroconvulsive Therapy a

P. Cowen, 1986, Annals of the New York Academy of Sciences.

Acute effects of LI 160 (extract of Hypericum perforatum, St John's wort) and two of its constituents on neuroendocrine responses in the rat

P. Cowen, M. Franklin, M. Mannel, 2000, Journal of Psychopharmacology.

NK1 receptor antagonism and emotional processing in healthy volunteers

P. Cowen, G. Goodwin, C. Harmer, 2010, Journal of psychopharmacology.

Evidence-based guidelines for treating depressive disorders with antidepressants: A revision of the 2008 British Association for Psychopharmacology guidelines

A Malizia, P. Cowen, A. Malizia, 2015, Journal of psychopharmacology.

Evidence-based guidelines for treating depressive disorders with antidepressants: A revision of the 2000 British Association for Psychopharmacology guidelines

P. Cowen, I. Anderson, P. Cowen, 2008, Journal of psychopharmacology.

Correction: Whole-blood expression of inflammasome- and glucocorticoid-related mRNAs correctly separates treatment-resistant depressed patients from drug-free and responsive patients in the BIODEP study

E. Bullmore, P. Cowen, W. Drevets, 2020, Translational Psychiatry.

P. Cowen, A. Sharpley, R. Solomon, 2005, Psychopharmacology.

Slow wave sleep and 5-HT2 receptor sensitivity in generalised anxiety disorder: a pilot study with ritanserin

P. Cowen, A. Sharpley, J. Davis, 2005, Psychopharmacology.

Effect of the 5-HT1A partial agonist buspirone on regional cerebral blood flow in man

Karl J. Friston, R. Dolan, P. Cowen, 2005, Psychopharmacology.

Sleep stability with home sleep recording and automatic sleep stage analysis.

P. Cowen, A. Sharpley, P J Cowen, 1990, Sleep.

The effects of chronic administration of hydrocortisone on cognitive function in normal male volunteers

T. Robbins, A. Young, P. Cowen, 1999, Psychopharmacology.

Changes in platelet alpha 2-adrenoceptor binding post partum: possible relation to maternity blues.

P. Cowen, M. Gelder, D. Grahame-Smith, 1983, The Lancet.

Tryptophan depletion in normal volunteers produces selective impairments in learning and memory

J. T. Coull, T. Robbins, A. Young, 1994, Neuropharmacology.

Pharmacotherapy of Suicidal Ideation and Behaviour

P. Cowen, R. Verkes, 2008 .

Lithium in Tricyclic-Resistant Depression Correlation of Increased Brain 5-HT Function with Clinical Outcome

Philip R. Cohen, P. Cowen, D. Julier, 1991, British Journal of Psychiatry.

Oxytocin enhances processing of positive versus negative emotional information in healthy male volunteers

P. Cowen, C. Harmer, R. Massey-Chase, 2009, Journal of psychopharmacology.

SSRI treatment decreases prolactin and hyperthermic responses to mCPP

P. Cowen, D. Quested, P. Sargent, 1997, Psychopharmacology.

Optimal dose of selective serotonin reuptake inhibitors, venlafaxine, and mirtazapine in major depression: a systematic review and dose-response meta-analysis

P. Cowen, M. Egger, T. Furukawa, 2019, The lancet. Psychiatry.

Effect of the NMDA receptor partial agonist, d-cycloserine, on emotional processing and autobiographical memory

P. Cowen, C. Harmer, Runsen Chen, 2020, Psychological Medicine.

Optimal dosing of antidepressant drugs - Authors' reply.

P. Cowen, M. Egger, T. Furukawa, 2019, The lancet. Psychiatry.

Pramipexole Enhances Reward Learning by Preserving Value Estimates

P. Cowen, C. Harmer, M. Browning, 2022, Biological Psychiatry.

Advances in psychopharmacology: mood disorders and dementia.

P. Cowen, P. Cowen, 1996, British medical bulletin.

Subcortical brain alterations in major depressive disorder: findings from the ENIGMA Major Depressive Disorder working group

Lachlan T. Strike, T. V. van Erp, I. Hickie, 2015, Molecular Psychiatry.

3,4-methylenedioxymethamphetamine (MDMA)-assisted psychotherapy for post-traumatic stress disorder in service personnel.

P. Cowen, A. Cipriani, 2018, The lancet. Psychiatry.

The pharmacological bases for repurposing statins in depression: a review of mechanistic studies

P. Cowen, C. Harmer, G. Maina, 2023, Translational psychiatry.

Allelic variation in the 5-HT2C receptor (HTR2C) and functional responses to the 5-HT2C receptor agonist, m-chlorophenylpiperazine

Paul J. Harrison, P. Cowen, D. Quested, 1999, Psychopharmacology.

Allelic variation in the 5-HT2C receptor (HT2RC) and the increase in slow wave sleep produced by olanzapine

Paul J. Harrison, P. Cowen, A. Sharpley, 2000, Psychopharmacology.

Effects of carbamazepine on sleep in healthy volunteers

P. Cowen, A. Sharpley, P. Cowen, 1989, Biological Psychiatry.

Practical problems in clinical psychiatry

P. Cowen, K. Hawton, 1992 .

P.283 Decreased resting state functional connectivity as a biomarker of poor response to escitalopram in patients with depression

P. Cowen, N. Filippini, C. Harmer, 2020, European Neuropsychopharmacology.

Higher immune-related gene expression in major depression is independent of CRP levels: results from the BIODEP study

E. Bullmore, P. Cowen, W. Drevets, 2023, Translational psychiatry.

Subcortical brain structure and suicidal behaviour in major depressive disorder: a meta-analysis from the ENIGMA-MDD working group

Lachlan T. Strike, T. V. van Erp, H. Christensen, 2017, Translational Psychiatry.

How Cannabis Causes Paranoia: Using the Intravenous Administration of ∆9-Tetrahydrocannabinol (THC) to Identify Key Cognitive Mechanisms Leading to Paranoia

Paul J. Harrison, G. Dunn, P. Cowen, 2014, Schizophrenia bulletin.

Changes in brain Glx in depressed bipolar patients treated with lamotrigine: A proton MRS study

P. Cowen, B. Godlewska, U. Emir, 2019, Journal of affective disorders.

Short-term escitalopram treatment and hippocampal volume

P. Cowen, B. Godlewska, A. Igoumenou, 2014, Psychopharmacology.

Early markers of cognitive enhancement: developing an implicit measure of cognitive performance

P. Cowen, C. Harmer, M. Browning, 2013, Psychopharmacology.

NK1 receptor antagonism and the neural processing of emotional information in healthy volunteers.

P. Cowen, C. Harmer, C. McCabe, 2009, The international journal of neuropsychopharmacology.

Psychiatry of the Elderly

Paul J. Harrison, P. Cowen, T. Burns, 1996, European Archives of Psychiatry and Clinical Neuroscience.

Personality and personality disorder

Paul J. Harrison, P. Cowen, T. Burns, 2012 .

Serotonin and depression: pathophysiological mechanism or marketing myth?

P. Cowen, 2008, Trends in pharmacological sciences.

Has psychopharmacology got a future?

P. Cowen, 2011, British Journal of Psychiatry.

Effects of 7 days of treatment with the cannabinoid type 1 receptor antagonist, rimonabant, on emotional processing

P. Cowen, C. Harmer, M. Browning, 2012, Journal of psychopharmacology.

Affective modulation of anterior cingulate cortex in young people at increased familial risk of depression

P. Cowen, C. Harmer, B. Inkster, 2008, British Journal of Psychiatry.

How do antidepressants work? New perspectives for refining future treatment approaches.

P. Cowen, C. Harmer, R. Duman, 2017, The lancet. Psychiatry.

Fronto-limbic effective connectivity as possible predictor of antidepressant response to SSRI administration

P. Cowen, C. Harmer, B. Godlewska, 2016, European Neuropsychopharmacology.

Haloperidol reduces stroop interference and increases negative priming in healthy people

J. Rawlins, P. Cowen, D. Geaney, 1996, Schizophrenia Research.

Abnormalities of sleep in patients with the chronic fatigue syndrome.

P. Cowen, R. Morriss, M. Sharpe, 1993, BMJ.

Corrigendum to “Beta adrenergic blockade reduces utilitarian judgment” [Biol. Psychol. 92 (2) (2013) 323–328]

P. Cowen, M. Hewstone, G. Kahane, 2014, Biological Psychology.

Does baseline fatigue influence treatment response to reboxetine or citalopram in depression? An open label randomized controlled trial

T. Peters, P. Cowen, D. Nutt, 2012, Journal of psychopharmacology.

PAX-D: study protocol for a randomised placebo-controlled trial evaluating the efficacy and mechanism of pramipexole as add-on treatment for people with treatment resistant depression

R. Bogacz, P. Cowen, C. Harmer, 2021, Evidence-Based Mental Health.

The Creation of Psychopharmacology. By D. Healy. (Pp. 416; £27.50.) Harvard University Press: London. 2003.

P. Cowen, 2004, Psychological Medicine.

Repeated administration of citalopram or reboxetine reduces the perception of negative emotions from facial expression.

P. Cowen, C. Harmer, G. Goodwin, 2002 .

Simplified quantification of 5-HT2A receptors in the human brain with [11C]MDL 100,907 PET and non-invasive kinetic analyses

P. Cowen, P. Grasby, Z. Bhagwagar, 2010, NeuroImage.

Early increase in marker of neuronal integrity with antidepressant treatment of major depression : 1 H magnetic resonance spectroscopy of

P. Cowen, S. Selvaraj, B. Godlewska, 2012 .

P.361 Brain serotonin release reduced among patients with severe depression: a pet study with [11c]cimbi-36 and d-amphetamine challenge

P. Cowen, O. Howes, J. Passchier, 2019, European Neuropsychopharmacology.

GABA and mood disorders

P. Cowen, Z. Bhagwagar, T. Sharp, 2003, Psychological Medicine.

The effect of amitriptyline treatment on the growth hormone response to apomorphine

P. Cowen, B. Gosden, L. Braddock, 2004, Psychopharmacology.

Psychopharmacology in medical practice

P. Cowen, 2010, Oxford Textbook of Medicine.

Pharmacological interventions for insomnia disorder in adults – Authors' reply

P. Cowen, A. Cipriani, E. Ostinelli, 2022, The Lancet.

Tryptophan depletion does not lower brain GABA levels in healthy volunteers

P. Cowen, P. Jezzard, S. Selvaraj, 2006, Psychopharmacology.

Lack of effect of a single dose of hydrocortisone on serotonin1A receptors in recovered depressed patients measured by positron emission tomography with [11C]WAY-100635

P. Cowen, P. Grasby, Z. Bhagwagar, 2003, Biological Psychiatry.

New approaches to treating resistant depression

P. Cowen, I. Anderson, 2015, BJPsych Advances.

5-HT neuroendocrine responses during psychotropic drug treatment: an investigation of the effects of lithium

Karl J. Friston, Philip R. Cohen, P. Cowen, 1990, Journal of Neuroscience Methods.

Intravenous administration of haloperidol to healthy volunteers: lack of subjective effects but clear objective effects

J. Rawlins, P. Cowen, D. Geaney, 1997, Journal of psychopharmacology.

Short-term antidepressant treatment Short-term antidepressant treatment

P. Cowen, C. Mackay, R. Norbury, 2007 .

Pet Measurement of the Effect of Dietary Tyrosine Depletion on [11C]Raclopride Binding: An [11C]Raclopride Pet Study

P. Cowen, P. Grasby, A. Montgomery, 2003 .

Does melatonin treatment change emotional processing? Implications for understanding the antidepressant mechanism of agomelatine

P. Cowen, C. Harmer, A. Pringle, 2015, Journal of psychopharmacology.

Effects of pramipexole on the processing of rewarding and aversive taste stimuli

P. Cowen, C. Harmer, C. McCabe, 2013, Psychopharmacology.

Lack of Effect of Tyrosine Depletion on Mood in Recovered Depressed Women

P. Cowen, C. Harmer, Z. Mannie, 2005, Neuropsychopharmacology.