J. Weiler

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Exercise-induced asthma: a practical guide to definitions, diagnosis, prevalence, and treatment.

J. Weiler, 1996, Allergy and asthma proceedings.

Control of the amplification convertase of complement by the plasma protein beta1H.

J. Weiler, D. Fearon, K. Austen, 1976, Proceedings of the National Academy of Sciences of the United States of America.

Randomized, Double‐Blind, Crossover, Clinical‐End‐Point Pilot Study to Examine the Use of Exhaled Nitric Oxide as a Bioassay for Dose Separation of Inhaled Fluticasone Propionate

J. Weiler, C. Sorkness, L. Hendeles, 2018, Journal of clinical pharmacology.

First do no harm: managing antihistamine impairment in patients with allergic rhinitis.

Philip D. Harvey, J. Weiler, T. Casale, 2003, The Journal of allergy and clinical immunology.

Effects of Fexofenadine, Diphenhydramine, and Alcohol on Driving Performance

John R Bloomfield, Timothy L Brown, Ginger S Watson, 2000, Annals of Internal Medicine.

Effects of fexofenadine, diphenhydramine, and alcohol on driving performance. A randomized, placebo-controlled trial in the Iowa driving simulator.

G S Watson, J M Weiler, J R Bloomfield, 2000, Annals of internal medicine.

Pathogenesis, Prevalence, Diagnosis, and Management of Exercise-induced Bronchoconstriction: a Practice Parameter These Parameters Were Developed by the Joint Task Force on Practice

S. Anderson, J. Weiler, S. Spector, 2022 .

Anaphylaxis in the general population: A frequent and occasionally fatal disorder that is underrecognized.

J. Weiler, 1999, The Journal of allergy and clinical immunology.

Onset of action, efficacy, and safety of fexofenadine 60 mg/pseudoephedrine 120 mg versus placebo in the Atlanta allergen exposure unit.

J. Weiler, G. Woodworth, R. Berkowitz, 2002, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

Special Considerations and Perspectives for Exercise-Induced Bronchoconstriction (EIB) in Olympic and Other Elite Athletes.

J. Weiler, J. Zeiger, 2020, The journal of allergy and clinical immunology. In practice.

Asthma in United States olympic athletes who participated in the 1998 olympic winter games.

J. Weiler, E. Ryan, 2000, The Journal of allergy and clinical immunology.

Interaction of heparin with synthetic antithrombin III peptide analogues.

U. R. Desai, J. Weiler, R. Linhardt, 1994, The Biochemical journal.

Medical modifiers of sports injury. The use of nonsteroidal anti-inflammatory drugs (NSAIDs) in sports soft-tissue injury.

J. Weiler, 1992, Clinics in sports medicine.

Safety of Binodenoson, a Selective Adenosine A2A Receptor Agonist Vasodilator Pharmacological Stress Agent, in Healthy Subjects With Mild Intermittent Asthma

E. R. Mcfadden, J. Weiler, W. Busse, 2009, Circulation. Cardiovascular imaging.

Heparin detection by the activated coagulation time: a comparison of the sensitivity of coagulation tests and heparin assays.

J. Weiler, D. Murray, J. Olson, 1997, Journal of cardiothoracic and vascular anesthesia.

Allergic and respiratory disease in sports medicine

J. Weiler, 1997 .

Structure-function relationships in the heparin-binding C-terminal region of insulin-like growth factor binding protein-3.

J. Weiler, M. Boes, R. Linhardt, 1996, Growth regulation.

Antithrombin III regulates complement activity in vitro.

J. Weiler, R. Linhardt, 1991, Journal of immunology.

Serious adverse reactions to protamine sulfate: are alternatives needed?

J. Weiler, H. Richerson, Z. Ballas, 1985, The Journal of allergy and clinical immunology.

Protamine-induced fatal anaphylaxis. Prevalence of antiprotamine immunoglobulin E antibody.

J. Weiler, B. Ginsberg, H. Richerson, 1985, The Journal of thoracic and cardiovascular surgery.

Heparin and modified heparin inhibit complement activation in vivo.

J. Weiler, R. Linhardt, R. E. Edens, 1992, Journal of immunology.

Clinical Practice Guideline An Official American Thoracic Society Clinical Practice Guideline : Exercise-induced Bronchoconstriction

Fern M. Cheek, S. Anderson, J. Weiler, 2013 .

Effect of IGFBP-derived peptides on incorporation of(35)SO(4)into proteoglycans.

J. Weiler, M. Boes, R. S. Bar, 2000, Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society.

Heparin binding and augmentation of C1 inhibitor activity.

J. Weiler, R. Linhardt, V. Vandernoot, 1999, Archives of biochemistry and biophysics.

Interaction of fibroblast growth factor-1 and related peptides with heparan sulfate and its oligosaccharides.

J. Weiler, R. Linhardt, R. Hileman, 1997, Archives of biochemistry and biophysics.

Importance of specific amino acids in protein binding sites for heparin and heparan sulfate.

J. Weiler, R. Linhardt, J. Fromm, 1996, The international journal of biochemistry & cell biology.

Preparation and biological activity of N-sulfonated chondroitin and dermatan sulfate derivatives.

J. Weiler, R. Linhardt, T. Toida, 1996, Carbohydrate research.

Differences in the interaction of heparin with arginine and lysine and the importance of these basic amino acids in the binding of heparin to acidic fibroblast growth factor.

J. Weiler, R. Linhardt, R. Hileman, 1995, Archives of biochemistry and biophysics.

Homogeneous, structurally defined heparin-oligosaccharides with low anticoagulant activity inhibit the generation of the amplification pathway C3 convertase in vitro.

J. Weiler, R. Linhardt, J. Engelken, 1988, The Journal of biological chemistry.

Comparison of mannitol and methacholine to predict exercise-induced bronchoconstriction and a clinical diagnosis of asthma

S. Anderson, J. Weiler, S. Spector, 2009, Respiratory research.

Exercise‐induced hypersensitivity syndromes in recreational and competitive athletes: a PRACTALL consensus report (what the general practitioner should know about sports and allergy)

J. Weiler, W. Henderson, T. Casale, 2008, Allergy.

Multicenter, double-blind, multiple-dose, parallel-groups efficacy and safety trial of azelastine, chlorpheniramine, and placebo in the treatment of spring allergic rhinitis.

J. Weiler, L. Diamond, J. T. Connell, 1988, The Journal of allergy and clinical immunology.

Fluticasone propionate aqueous nasal spray compared with terfenadine tablets in the treatment of seasonal allergic rhinitis.

J. Weiler, R. Dockhorn, E. Meltzer, 1996, The Journal of allergy and clinical immunology.

A dose-ranging study of the efficacy and safety of azelastine nasal spray in the treatment of seasonal allergic rhinitis with an acute model.

J. Weiler, E. Meltzer, J. Freitag, 1994, The Journal of allergy and clinical immunology.

The Effectiveness of Oral Azelastine in the Management of Perennial Allergic Rhinitis

J. Weiler, E. Meltzer, J. Freitag, 1994 .

Prevalence of bronchial hyperresponsiveness in highly trained athletes.

J. Weiler, E. Crowley, W. Metzger, 1986, Chest.

A prospective study of the risk of an immediate adverse reaction to protamine sulfate during cardiopulmonary bypass surgery.

J. Weiler, W. Clarke, J. Carter, 1990, The Journal of allergy and clinical immunology.

Asthma history Exercise-induced chest tightness Exercise-induced cough Exercise-induced wheezing Exercise-induced prolonged dyspnea Ever have chest

J. Weiler, J. Metzger, M. Sharath, 2006 .

Clinical and immunologic evaluation of glutaraldehyde-modified tyrosine-adsorbed short ragweed extract: a double-blind, placebo-controlled trial.

J. Weiler, H. Richerson, D. Moran, 1981, The Journal of allergy and clinical immunology.

Safety and efficacy of loratadine (Sch-29851): a new non-sedating antihistamine in seasonal allergic rhinitis.

J. Weiler, R. Dockhorn, C. Falliers, 1987, Annals of allergy.

Why must olympic athletes prove that they have asthma to be permitted to take inhaled beta2-agonists?

J. Weiler, 2003, The Journal of allergy and clinical immunology.

Abnormal movement of the arytenoid region during exercise presenting as exercise-induced asthma in an adolescent athlete.

J. Weiler, R. Smith, D. Bittleman, 1994, Chest.

Complement inhibits immune responses: C3 preparations inhibit the generation of human cytotoxic T lymphocytes

J. Weiler, Z. Ballas, T. Feldbush, 1983, European journal of immunology.

glutaraldehyde-modified, tyrosine-adsorbed short ragweed extract: a double-blind, placebo-controlled trial

J. Weiler, H. Richerson, D. Moran, 1981 .

Human Hepatitis B Antibody: Evaluation of Assays and Development of a Reference Panel

J. Weiler, G. Grady, 1974, Transfusion.

Human lymphocyte transformation induced by mitogens and antigens in a serum-free tissue culture system.

J. Weiler, B. Needleman, 1981, Journal of immunological methods.

American Thoracic Society Documents An Official American Thoracic Society Clinical Practice Guideline : Exercise-induced Bronchoconstriction

Fern M. Cheek, S. Anderson, J. Weiler, 2013 .

Airway responses to methacholine in asymptomatic nonatopic cigarette smokers.

J. Weiler, T. Casale, A. Donnelly, 1987, Journal of applied physiology.

Discussion of risk of scuba diving in individuals with allergic and respiratory diseases: SCUBA Subcommittee.

J. H. Wells, J. Weiler, F. Virant, 1995, The Journal of allergy and clinical immunology.

Airway reactivity to methacholine in nonatopic asymptomatic adults.

J. Weiler, T. Casale, A. Donnelly, 1988, Journal of applied physiology.

Efficacy and safety of clemastine-pseudoephedrine-acetaminophen versus pseudoephedrine-acetaminophen in the treatment of seasonal allergic rhinitis in a 1-day, placebo-controlled park study.

J. Weiler, T. Casale, E. Meltzer, 2003, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

Pathways of complement activation in membranoproliferative glomerulonephritis and allograft rejection.

J. Weiler, D. Fearon, T. Strom, 1977, Transplantation Proceedings.

Athletes, Asthma, and Doping

J. Weiler, E. Ryan, 2001 .

Gradient polyacrylamide gel electrophoresis for determination of molecular weights of heparin preparations and low-molecular-weight heparin derivatives.

J. Weiler, A. Al-Hakim, R. Linhardt, 1992, Journal of pharmaceutical sciences.

Eosinophil granule major basic protein regulates generation of classical and alternative-amplification pathway C3 convertases in vitro.

J. Weiler, G. Gleich, 1988, Journal of immunology.

Human secondary immune responses induced by influenza in a serum-free tissue culture system.

J. Weiler, R. Yarchoan, S. Rinderknecht, 1985, Journal of immunological methods.

Human immunoglobulin biosynthesis in a serum-free medium.

J. Weiler, S. Rinderknecht, M. Sharath, 1984, The Journal of laboratory and clinical medicine.

Azelastine nasal spray as adjunctive therapy to azelastine tablets in the management of seasonal allergic rhinitis.

J. Weiler, E. Meltzer, 1997, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

Azelastine nasal spray in the management of seasonal allergic rhinitis.

J. Weiler, R. Dockhorn, E. Meltzer, 1994, Annals of allergy.

Randomized, double-blind, parallel groups, placebo-controlled study of efficacy and safety of Rynatan in the treatment of allergic rhinitis using an acute model.

J. Weiler, K. Weiler, A. Donnelly, 1990, Annals of allergy.

Recurrent infections, pericarditis and renal disease in a patient with total C2 deficiency and decreased NK cell function consistent with acute rheumatic fever and systemic lupus erythematosus.

J. Weiler, P. Densen, S. Bonsib, 1994, Annals of the rheumatic diseases.

Pattern and spacing of basic amino acids in heparin binding sites.

J. Weiler, R. Linhardt, R. Hileman, 1997, Archives of biochemistry and biophysics.

Cytokine and complement levels in patients undergoing cardiopulmonary bypass.

J. Weiler, D. Kapelanski, J. Olson, 1993, The Journal of thoracic and cardiovascular surgery.

Tonsillectomy in a patient with hereditary angioedema after prophylaxis with C1 inhibitor concentrate.

J. Weiler, K. K. Maves, 1994, Annals of allergy.

Certain high molecular weight heparin chains have high affinity for vitronectin.

J. Weiler, R. Linhardt, L. LeBrun, 2001, Archives of biochemistry and biophysics.

Comparison of the activity of polyanions and polycations on the classical and alternative pathways of complement.

J. Weiler, R. Linhardt, 1989, Immunopharmacology.

Modulation of the formation of the amplification convertase of complement, C3b, Bb, by native and commercial heparin

J. Weiler, D. Fearon, K. Austen, 1978, The Journal of experimental medicine.

Complement in Health and Disease

J. Weiler, K. Whaley, M. Loos, 2012, Immunology and Medicine.

Cimetidine-induced cutaneous vasculitis.

J. Weiler, A. R. Magnusson, G. Mitchell, 1983, The American journal of medicine.

Expression of C1 esterase inhibitor by the baculovirus expression vector system: preparation, purification, and characterization.

J. Weiler, R. Linhardt, D. Murhammer, 2001, Protein expression and purification.

Risk of transfusing blood containing antibody to hepatitis-B surface antigen.

J. Weiler, P. Holland, H. Alter, 1974, Lancet.

Modulation of Generation of the Amplification Convertase C3b,Bb by Heparin

J. Weiler, K. Austen, R. Yurt, 1978, The Journal of Immunology.

Glycosaminoglycan‐protein interactions: definition of consensus sites in glycosaminoglycan binding proteins

J. Weiler, R. Hileman, J. Fromm, 1998, BioEssays : news and reviews in molecular, cellular and developmental biology.

Asthma in Athletes

J. Weiler, J. Brannan, 2018, Allergy and Asthma.

Exercise-induced bronchoconstriction update-2016.

J. Weiler, D. Bernstein, J. Portnoy, 2016, The Journal of allergy and clinical immunology.

Practice parameter Exercise-induced bronchoconstriction update — 2016

J. Weiler, D. Bernstein, J. Portnoy, 2016 .

IGFBP-3 and IGFBP-5 association with endothelial cells: role of C-terminal heparin binding domain.

J. Weiler, M. Boes, R. Linhardt, 1995, Growth regulation.

Complement fragments suppress lymphocyte immune responses.

J. Weiler, Z. Ballas, M. Hobbs, 1982, Immunology today.

Familial properdin deficiency and fatal meningococcemia. Correction of the bactericidal defect by vaccination.

J. Weiler, P. Densen, J. M. Griffiss, 1987, The New England journal of medicine.

Anaphylactoid reactions to vascular graft material presenting with vasodilation and subsequent disseminated intravascular coagulation.

J. Weiler, M. Roizen, M. Shuman, 1989, Anesthesiology.

C1 Esterase Inhibitor Deficiency, Airway Compromise, and Anesthesia

J. Weiler, N. F. Jensen, 1998, Anesthesia and analgesia.

Does heparin prophylaxis prevent exacerbations of hereditary angioedema?

J. Weiler, G. Woodworth, T. Layton, 2002, The Journal of allergy and clinical immunology.

A review of the reported defects in the human C1 esterase inhibitor gene producing hereditary angioedema including four new mutations.

J. Weiler, B. Bowen, S. Hovick, 2001, Clinical immunology.

Angioedema of the tongue--cause?

J. Weiler, K. K. Maves, 1992, Anesthesia and analgesia.

Inhibition of secondary in vitro antibody responses by the third component of complement.

J. Weiler, M. Hobbs, T. Feldbush, 1982, Journal of immunology.

Properdin: Approaching four decades of research

J. Weiler, K. K. Maves, Karen K. Maves, 1993, Immunologic research.

Contamination of intradermal skin test syringes.

J. Weiler, F. Koontz, H. Richerson, 1985, The Journal of allergy and clinical immunology.

Steroids inhibit activation of the alternative-amplification pathway of complement

J. Weiler, B. D. Packard, 1983, Infection and immunity.

Methylprednisolone inhibits the alternative and amplification pathways of complement

J. Weiler, B. D. Packard, John M. Weileri, 1982, Infection and immunity.

C1 INH deficiency and angioedema: a spectrum of disease. Part one.

J. Weiler, J. Grem, P. Halverson, 1984, Annals of allergy.

The third component of complement inhibits human lymphocyte blastogenesis.

J. Weiler, T. Feldbush, B. Needleman, 1981, Journal of immunology.

Role of complement in the immune response.

J. Weiler, Z. Ballas, M. Hobbs, 1984, Federation proceedings.

National Athletic Trainers' Association position statement: management of asthma in athletes.

Michael G. Miller, J. Weiler, R. Baker, 2005, Journal of athletic training.

Comparative outdoor study of the efficacy, onset and duration of action, and safety of cetirizine, loratadine, and placebo for seasonal allergic rhinitis.

J. Weiler, E. Meltzer, M. D. Widlitz, 1996, The Journal of allergy and clinical immunology.

Improving screening and diagnosis of exercise-induced bronchoconstriction: a call to action.

J. Weiler, T. Hallstrand, A. Bronstone, 2014, The journal of allergy and clinical immunology. In practice.

Fluticasone furoate/vilanterol versus fluticasone propionate in patients with asthma and exercise-induced bronchoconstriction

J. Weiler, P. O'Byrne, L. Jacques, 2020, Journal of Asthma.

Asthma and athletes

J. Weiler, C. Malloy, 2005, Clinical reviews in allergy & immunology.

Asthma in United States Olympic athletes who participated in the 1996 Summer Games.

J. Weiler, T. Layton, Teresa A Layton, 1998, The Journal of allergy and clinical immunology.

Two-dimensional affinity resolution electrophoresis demonstrates that three distinct heparin populations interact with antithrombin III.

J. Weiler, R. Linhardt, R. E. Edens, 1995, Biochemistry.

Polyions regulate the alternative amplification pathway of complement.

J. Weiler, 1983, Immunopharmacology.

Metabolic alteration of the N-glycan structure of a protein from patients with a heterozygous protein deficiency.

J. Weiler, R. Linhardt, Fuming Zhang, 2004, Biochimica et biophysica acta.

Heparin and derivatized heparin inhibit zymosan and cobra venom factor activation of complement in serum.

J. Weiler, R. Linhardt, R. E. Edens, 1994, Immunopharmacology.

Regulation of C5 convertase activity by properdin, factors B and H

J. Weiler, 1989, Immunologic research.

Small heparin fragments regulate the amplification pathway of complement.

J. Weiler, R. Linhardt, K. Rice, 1985, Immunopharmacology.

Quality of patient-reported outcome data captured using paper and interactive voice response diaries in an allergic rhinitis study: is electronic data capture really better?

J. Weiler, G. Woodworth, A. Christ, 2004, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

Sedation, cognition, and antihistamines

J. Weiler, G. Watson, J. Qidwai, 2002, Current allergy and asthma reports.

American Academy of Allergy, Asthma & Immunology Work Group report: exercise-induced asthma.

J. Weiler, S. Bonini, L. Delgado, 2007, The Journal of allergy and clinical immunology.

Work Group Report* American Academy of Allergy, Asthma & Immunology Work Group Report: Exercise-induced asthma

J. Weiler, S. Bonini, D. Passali, 2007 .

Reproducibility of the airway response to an exercise protocol standardized for intensity, duration, and inspired air conditions, in subjects with symptoms suggestive of asthma

S. Anderson, C. P. Perry, J. Weiler, 2010, Respiratory research.

Human liver-derived HEP G2 cells produce functional properdin.

J. Weiler, K. K. Maves, 1994, The Journal of laboratory and clinical medicine.

The Natural Modulation of the Amplification Phase of Complement Activation

J. Weiler, D. Fearon, K. Austen, 1976, Transplantation reviews.

Effect of fluticasone/salmeterol administered via a single device on exercise-induced bronchospasm in patients with persistent asthma.

P. Dorinsky, J. Weiler, N. Rupp, 2005, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

Onset-of-action for antihistamine and decongestant combinations during an outdoor challenge.

J. Weiler, M. Kaliner, E. Meltzer, 2000, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

Detection of properdin mRNA in human peripheral blood monocytes and spleen.

J. Weiler, K. K. Maves, 1992, Journal of Laboratory and Clinical Medicine.

Eosinophil granule cationic proteins regulate the classical pathway of complement.

J. Weiler, G. Gleich, R. E. Edens, 1995, Immunology.

Eosinophil granule cationic proteins regulate complement. I. Activity on the alternative pathway.

J. Weiler, G. Gleich, R. E. Edens, 1992, Journal of immunology.

The real-world risk of taking sedating antihistamines.

J. Weiler, 2002, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

Corticosteroid-sparing effect of azelastine in the management of bronchial asthma.

J. Weiler, R. Dockhorn, W. Busse, 1996, American journal of respiratory and critical care medicine.

Data Capture from the Sponsors’ And Investigators’ Perspectives: Balancing Quality, Speed, and Cost

John M. Weiler, J. Weiler, Amy J. Lampe, 1998 .

A report of a rare immediate reaction after ingestion of acetaminophen.

J. Weiler, J. Grant, 2001, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.