J. Nerbonne

发表

Imaging Neuronal Subsets in Transgenic Mice Expressing Multiple Spectral Variants of GFP

G. Feng, J. Sanes, J. Lichtman, 2000, Neuron.

Exercise training and PI3Kα-induced electrical remodeling is independent of cellular hypertrophy and Akt signaling.

J. Nerbonne, Kai-Chien Yang, Y. Tseng, 2012, Journal of molecular and cellular cardiology.

Molecular determinants of cardiac transient outward potassium current (I(to)) expression and regulation.

J. Nerbonne, Noriko Niwa, 2010, Journal of molecular and cellular cardiology.

Molecular physiology of cardiac repolarization.

J. Nerbonne, R. Kass, 2005, Physiological reviews.

Sudden Cardiac Death Prediction and Prevention

Mark E. Anderson, N. Trayanova, J. Nerbonne, 2010 .

Sudden Cardiac Death Prediction and Prevention: Report From a National Heart, Lung, and Blood Institute and Heart Rhythm Society Workshop

Mark E. Anderson, N. Trayanova, J. Nerbonne, 2010, Circulation.

Diversity and functional roles of K + channels in cardiac repolarization : from single cell to whole organ levels

Jamie, J. Nerbonne, J. Weiss, 2016 .

Accessory Kv&bgr;1 Subunits Differentially Modulate the Functional Expression of Voltage-Gated K+ Channels in Mouse Ventricular Myocytes

J. Nerbonne, K. Rhodes, F. Aimond, 2005 .

Atrial L-type Ca2+ currents and human atrial fibrillation.

J. Nerbonne, D. V. Van Wagoner, P. McCarthy, 1999, Circulation research.

How to Build an Integrated Biobank: The Washington University Translational Cardiovascular Biobank & Repository Experience

G. Ewald, J. Nerbonne, M. Pasque, 2013, Clinical and translational science.

Deep RNA Sequencing Reveals Dynamic Regulation of Myocardial Noncoding RNAs in Failing Human Heart and Remodeling With Mechanical Circulatory Support

G. Ewald, J. Nerbonne, D. Mann, 2014, Circulation.

Inherited Arrhythmias: A National Heart, Lung, and Blood Institute and Office of Rare Diseases Workshop Consensus Report About the Diagnosis, Phenotyping, Molecular Mechanisms, and Therapeutic Approaches for Primary Cardiomyopathies of Gene Mutations Affecting Ion Channel Function

Michael J Ackerman, Colleen E Clancy, Stephan E Lehnart, 2007, Circulation.

A Fully Implantable Pacemaker for the Mouse: From Battery to Wireless Power

Igor R. Efimov, Jacob I. Laughner, Erik R. Zellmer, 2013, PloS one.

Molecular basis of transient outward K+ current diversity in mouse ventricular myocytes

J. Nerbonne, B. London, Weinong Guo, 1999, The Journal of physiology.

Mechanisms contributing to myocardial potassium channel diversity, regulation and remodeling.

Kai-Chien Yang, Jeanne M Nerbonne, J. Nerbonne, 2016, Trends in cardiovascular medicine.

Differential depression of inhibitory synaptic responses in feedforward and feedback circuits between different areas of mouse visual cortex

Andreas Burkhalter, Hongwei Dong, Jeanne M Nerbonne, 2004, The Journal of comparative neurology.

A critical role for PPARα-mediated lipotoxicity in the pathogenesis of diabetic cardiomyopathy: Modulation by dietary fat content

Xianlin Han, J. Nerbonne, R. Gross, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Potassium currents in the heart: functional roles in repolarization, arrhythmia and therapeutics

J. Nerbonne, J. Weiss, M. Sanguinetti, 2017, The Journal of physiology.

Physiological and pharmacological manipulations with light flashes.

H. Lester, J. Nerbonne, H A Lester, 1982, Annual review of biophysics and bioengineering.

The Sodium Channel Accessory Subunit Navβ1 Regulates Neuronal Excitability through Modulation of Repolarizing Voltage-Gated K+ Channels

Andrew J Link, Céline Marionneau, Jeanne M Nerbonne, 2012, The Journal of Neuroscience.

Distinct Balance of Excitation and Inhibition in an Interareal Feedforward and Feedback Circuit of Mouse Visual Cortex

Bryan M Hooks, Bryan M. Hooks, Andreas Burkhalter, 2013, The Journal of Neuroscience.

Electrical remodelling maintains firing properties in cortical pyramidal neurons lacking KCND2‐encoded A‐type K+ currents

A. Burkhalter, J. Nerbonne, Aaron J. Norris, 2008, The Journal of physiology.

Functional knockout of the transient outward current, long-QT syndrome, and cardiac remodeling in mice expressing a dominant-negative Kv4 alpha subunit.

J. Nerbonne, R. Schuessler, D. Barry, 1998, Circulation research.

Characterization of a novel, dominant negative KCNJ2 mutation associated with Andersen-Tawil syndrome

J. Nerbonne, P. Cuculich, S. Marrus, 2011, Channels.

Loss of Navβ4-Mediated Regulation of Sodium Currents in Adult Purkinje Neurons Disrupts Firing and Impairs Motor Coordination and Balance.

Joseph L. Ransdell, J. Nerbonne, P. Allen, 2017, Cell reports.

Loss of Navβ4-Mediated Regulation of Sodium Currents in Adult Purkinje Neurons Disrupts Firing and Impairs Motor Coordination and Balance.

Joseph L. Ransdell, J. Nerbonne, P. Allen, 2017, Cell reports.

Loss of Nav b 4-Mediated Regulation of Sodium Currents in Adult Purkinje Neurons Disrupts Firing and Impairs Motor Coordination and Balance Graphical Abstract Highlights

Joseph L. Ransdell, J. Nerbonne, P. Allen, 2017 .

Cardiac Mechano-Gated Ion Channels and Arrhythmias.

J. Nerbonne, P. Kohl, R. Peyronnet, 2016, Circulation research.

Four Kinetically Distinct Depolarization-activated K+ Currents in Adult Mouse Ventricular Myocytes

Weinong Guo, J. Nerbonne, Hao-dong Xu, 1999, The Journal of general physiology.

Regional differences in the expression of tetrodotoxin-sensitive inward Ca2+ and outward Cs+/K+ currents in mouse and human ventricles

J. Nerbonne, C. Balke, Wei Wang, 2019, Channels.

Early remodeling of repolarizing K+ currents in the αMHC403/+ mouse model of familial hypertrophic cardiomyopathy.

J. Nerbonne, J. Seidman, C. Seidman, 2017, Journal of molecular and cellular cardiology.

Molecular Basis of Functional Myocardial Potassium Channel Diversity.

J. Nerbonne, 2016, Cardiac electrophysiology clinics.

3 – Voltage-Regulated Potassium Channels

J. Nerbonne, 2014 .

In vivo effect of a dominant negative Kv4.2 loss-of-function mutation eliminating I(to,f) on atrial refractoriness and atrial fibrillation in mice.

J. Nerbonne, C. Bode, M. Zehender, 2009, Circulation journal : official journal of the Japanese Circulation Society.

Kv4.3 is not required for the generation of functional Ito,f channels in adult mouse ventricles.

J. Nerbonne, Céline Marionneau, Noriko Niwa, 2008, Journal of molecular and cellular cardiology.

PPARalpha-mediated remodeling of repolarizing voltage-gated K+ (Kv) channels in a mouse model of metabolic cardiomyopathy.

J. Nerbonne, Céline Marionneau, D. Kelly, 2008, Journal of molecular and cellular cardiology.

Heterogeneous expression of repolarizing, voltage‐gated K+ currents in adult mouse ventricles

J. Nerbonne, D. Fedida, F. Aimond, 2004, The Journal of physiology.

Selective elimination of I K , slow 1 in mouse ventricular myocytes expressing a dominant negative Kv 1 . 5 subunit

J. Nerbonne, Kathryn A. Yamada, W. Guo, 2003 .

Modulation of Kv4-encoded K+ Currents in the Mammalian Myocardium by Neuronal Calcium Sensor-1*

J. Nerbonne, A. Jeromin, D. Johns, 2002, The Journal of Biological Chemistry.

Functional expression of a GFP-tagged Kv1.5 α-subunit in mouse ventricle

J. Nerbonne, Hao-dong Xu, W. Guo, 2001 .

Resistance to Drug-Induced QT ProlongationK , slow I Sensitive Component of − Targeted Replacement of Kv 1 . 5 in the Mouse Leads to Loss of the 4-Aminopyridine

V. Shusterman, J. Nerbonne, Diomedes A. Logothetis, 2001 .

Targeted Replacement of Kv1.5 in the Mouse Leads to Loss of the 4-Aminopyridine-Sensitive Component of IK,slow and Resistance to Drug-Induced QT Prolongation

V. Shusterman, J. Nerbonne, Joseph A. Hill, 2001, Circulation research.

Molecular diversity of the repolarizing voltage‐gated K+ currents in mouse atrial cells

J. Nerbonne, E. Bou-Abboud, Huilin Li, 2000, The Journal of physiology.

Molecular correlates of the calcium‐independent, depolarization‐activated K+ currents in rat atrial myocytes

J. Nerbonne, E. Bou-Abboud, Elias Bou‐Abboud, 1999, The Journal of physiology.

Attenuation of the slow component of delayed rectification, action potential prolongation, and triggered activity in mice expressing a dominant-negative Kv2 alpha subunit.

J. Nerbonne, Weinong Guo, S. Brunet, 1999, Circulation research.

Proteomic analysis highlights the molecular complexities of native Kv4 channel macromolecular complexes.

J. Nerbonne, Céline Marionneau, R. Townsend, 2011, Seminars in cell & developmental biology.

Mass spectrometry-based identification of native cardiac Nav1.5 channel α subunit phosphorylation sites.

Cheryl F. Lichti, J. Nerbonne, Céline Marionneau, 2012, Journal of proteome research.

Phosphoproteomic Identification of CaMKII- and Heart Failure-Dependent Phosphorylation Sites on the Native Cardiac Nav1.5 Channel Protein

Cheryl F. Lichti, J. Nerbonne, Céline Marionneau, 2014 .

Expression and function of the low density lipoprotein receptor-related protein (LRP) in mammalian central neurons.

J. Nerbonne, A. Schwartz, G. Bu, 1994, The Journal of biological chemistry.

CD36 Protein Influences Myocardial Ca2+ Homeostasis and Phospholipid Metabolism

J. Nerbonne, I. Efimov, O. Kuda, 2012, The Journal of Biological Chemistry.

Calmodulin Kinase II Inhibition Enhances Ischemic Preconditioning by Augmenting ATP-Sensitive K+ Current

Mark E. Anderson, J. Nerbonne, Céline Marionneau, 2007, Channels.

Chapter 20 – Heterogenous Expression of Potassium Channels in the Mammalian Myocardium

J. Nerbonne, 2004 .

Mediation of Neuronal Apoptosis by Kv2.1-Encoded Potassium Channels

J. Nerbonne, E. Levitan, S. Pal, 2003, The Journal of Neuroscience.

Expression of Distinct ERG Proteins in Rat, Mouse, and Human Heart

J. Nerbonne, D. V. Van Wagoner, A. Shrier, 2000, The Journal of Biological Chemistry.

Endoplasmic Reticulum Protein TXNDC5 Augments Myocardial Fibrosis by Facilitating Extracellular Matrix Protein Folding and Redox-Sensitive Cardiac Fibroblast Activation

J. Nerbonne, Kai-Chien Yang, Chau-Chung Wu, 2018, Circulation research.

Cardiomyopathy Transgenic Expression of Fatty Acid Transport Protein 1 in the Heart Causes Lipotoxic

Xianlin Han, J. Nerbonne, T. Sharp, 2005 .

Transgenic Expression of Fatty Acid Transport Protein 1 in the Heart Causes Lipotoxic Cardiomyopathy

Xianlin Han, J. Nerbonne, T. Sharp, 2005, Circulation research.

Glucose transport and phosphorylation in single cardiac myocytes: rate-limiting steps in glucose metabolism.

J. Nerbonne, O. H. Lowry, J. Lawrence, 1994, The American journal of physiology.

Interconversion between distinct gating pathways of the high threshold calcium channel in rat ventricular myocytes.

J. Nerbonne, P. Charnet, S. Richard, 1993, The Journal of physiology.

Validation of a model for predicting drug-induced torsades de pointes: the risky business of assessing arrhythmogenic potential.

J. Nerbonne, Kathryn A. Yamada, 2006, Heart rhythm.

Distinct Cellular and Molecular Mechanisms Underlie Functional Remodeling of Repolarizing K+ Currents With Left Ventricular Hypertrophy

J. Nerbonne, T. Pilgram, Céline Marionneau, 2008, Circulation research.

Proteomic analyses of native brain KV4.2 channel complexes

Richard D. LeDuc, J. Nerbonne, R. LeDuc, 2009, Channels.

ERG proteins and functional cardiac I(Kr) channels in rat, mouse, and human heart.

J. Nerbonne, A. Pond, 2001, Trends in cardiovascular medicine.

Ca2+-Independent Alterations in Diastolic Sarcomere Length and Relaxation Kinetics in a Mouse Model of Lipotoxic Diabetic Cardiomyopathy

J. Nerbonne, J. Schaffer, T. Flagg, 2008, Circulation Research.

Two pathways for Ca2+ channel gating differentially modulated by physiological stimuli.

J. Nerbonne, F. Tiaho, P. Charnet, 1990, The American journal of physiology.

Cellular Biology Mitofusin 2-Containing Mitochondrial-Reticular Microdomains Direct Rapid Cardiomyocyte Bioenergetic Responses Via Interorganelle Ca Crosstalk

J. Nerbonne, G. Dorn, G. Csordás, 2012 .

Repolarizing cardiac potassium channels: multiple sites and mechanisms for CaMKII-mediated regulation.

J. Nerbonne, 2011, Heart rhythm.

Two functionally distinct 4-aminopyridine-sensitive outward K+ currents in rat atrial myocytes

J. Nerbonne, W. Boyle, Walter A. Boyle, 1992, The Journal of general physiology.

Selective elimination of I(K,slow1) in mouse ventricular myocytes expressing a dominant negative Kv1.5alpha subunit.

J. Nerbonne, Kathryn A. Yamada, W. Guo, 2004, American journal of physiology. Heart and circulatory physiology.

Accessory Kvbeta1 subunits differentially modulate the functional expression of voltage-gated K+ channels in mouse ventricular myocytes.

J. Nerbonne, K. Rhodes, F. Aimond, 2005, Circulation research.

Distribution, splicing and glucocorticoid-induced expression of cardiac alpha 1C and alpha 1D voltage-gated Ca2+ channel mRNAs.

J. Nerbonne, K. Takimoto, E. Levitan, 1997, Journal of molecular and cellular cardiology.

ER71 specifies Flk-1+ hemangiogenic mesoderm by inhibiting cardiac mesoderm and Wnt signaling.

J. Nerbonne, D. Lim, Kyunghee Choi, 2012, Blood.

ER71 speciﬁes Flk-1 (cid:1) hemangiogenic mesoderm by inhibiting cardiac mesoderm and Wnt signaling

J. Nerbonne, D. Lim, Kyunghee Choi, 2012 .

Characterization of mice with a combined suppression of I(to) and I(K,slow).

J. Nerbonne, G. Mitchell, G. Koren, 2001, American journal of physiology. Heart and circulatory physiology.

KChIP2 modulates the cell surface expression of Kv 1.5-encoded K(+) channels.

J. Nerbonne, W. Guo, Rebecca L. Mellor, 2005, Journal of molecular and cellular cardiology.

Transgenic Expression of FATP1 in the Heart Causes Lipotoxic Cardiomyopathy

Xianlin Han, J. Nerbonne, T. Sharp, 2004 .

Enzyme levels in cultured astrocytes, oligodendrocytes and Schwann cells, and neurons from the cerebral cortex and superior cervical ganglia of the rat

J. Nerbonne, O. H. Lowry, J. Carter, 1991, Neurochemical Research.

Distribution, Splicing and Glucocorticoid-Induced Expression of Cardiacα1Candα1DVoltage-gated Ca2+Channel mRNAs

J. Nerbonne, K. Takimoto, E. Levitan, 1997 .

Time course of the increase in the myocardial slow inward current after a photochemically generated concentration jump of intracellular cAMP.

H. Lester, J. Nerbonne, J. Nargeot, 1983, Proceedings of the National Academy of Sciences of the United States of America.

Accessory Kv (cid:1) 1 Subunits Differentially Modulate the Functional Expression of Voltage-Gated K (cid:2) Channels in Mouse Ventricular Myocytes Cellular Biology

J. Nerbonne, K. Rhodes, F. Aimond, 2005 .

Molecular basis of functional voltage‐gated K+ channel diversity in the mammalian myocardium

J. Nerbonne, 2000, The Journal of physiology.

Electro-mechanical coupling of KCNQ channels is a target of epilepsy-associated mutations and retigabine

J. Nerbonne, Jingyi Shi, J. Cui, 2022, Science advances.

Vascular actions of 'caged' phenylephrine analogs depend on the structure and site of attachment of the 2-nitrobenzyl group.

J. Nerbonne, W. Boyle, S. Muralidharan, 1997, Journal of photochemistry and photobiology. B, Biology.

Studying cardiac arrhythmias in the mouse--a reasonable model for probing mechanisms?

J. Nerbonne, 2004, Trends in cardiovascular medicine.

Integrated multi-omic characterization of congenital heart disease

Matthew C. Hill, D. Turaga, J. Nerbonne, 2022, Nature.

Functional and Molecular Diversity of Native Neuronal K+ Channels

J. Nerbonne, 2016 .

Liquid crystalline solvents as mechanistic probes. 3. The influence of ordered media on the efficiency of the photodimerization of acenaphthylene

J. Nerbonne, R. Weiss, 1979 .

Effects of liquid crystal solvents on the photodimerization of acenaphthylene

J. Nerbonne, R. Weiss, 1978 .

Kv4.2 potassium channels segregate to extrasynaptic domains and influence intrasynaptic NMDA receptor NR2B subunit expression

J. Nerbonne, A. Jeromin, F. Ferraguti, 2012, Brain Structure and Function.

Polycystin 2 is increased in disease to protect against stress-induced cell death

J. Nerbonne, L. Cantley, H. J. Chung, 2020, Scientific Reports.

Neuronal voltage-gated K+ (Kv) channels function in macromolecular complexes

J. Nerbonne, Aaron J. Norris, Nicholas C. Foeger, 2010, Neuroscience Letters.

Molecular Dissection of IA in Cortical Pyramidal Neurons Reveals Three Distinct Components Encoded by Kv4.2, Kv4.3, and Kv1.4 α-Subunits

J. Nerbonne, Aaron J. Norris, 2010, The Journal of Neuroscience.

Functional Role of the Fast Transient Outward K+ Current IA in Pyramidal Neurons in (Rat) Primary Visual Cortex

A. Burkhalter, J. Nerbonne, Weilong Yuan, 2005, The Journal of Neuroscience.

Delayed Rectifier K+ Currents,IK, Are Encoded by Kv2 α-Subunits and Regulate Tonic Firing in Mammalian Sympathetic Neurons

J. Nerbonne, Sacha A. Malin, 2002, The Journal of Neuroscience.

Voltage-gated potassium channels (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database

L. Jan, J. Nerbonne, B. Rudy, 2019, IUPHAR/BPS Guide to Pharmacology CITE.

Deletion of the Kv2.1 delayed rectifier potassium channel leads to neuronal and behavioral hyperexcitability

Jon T. Sack, J. Hell, J. Nerbonne, 2014, Genes, brain, and behavior.

Do Glia Have Heart? Expression and Functional Role forEther-A-Go-Go Currents in Hippocampal Astrocytes

J. Nerbonne, P. Schwartzkroin, L. Bianchi, 2000, The Journal of Neuroscience.

IA Channels Encoded by Kv1.4 and Kv4.2 Regulate Neuronal Firing in the Suprachiasmatic Nucleus and Circadian Rhythms in Locomotor Activity

J. Nerbonne, E. Herzog, Aaron J. Norris, 2012, The Journal of Neuroscience.

Photolabile "caged" adrenergic receptor agonists and related model compounds.

J. Nerbonne, S. Muralidharan, 1995, Journal of photochemistry and photobiology. B, Biology.

Elucidation of the thermal isomerization mechanism for azobenzene in a cholesteric liquid crystal solvent

J. Nerbonne, R. Weiss, 1978 .

Photochemically produced intracellular concentration jumps of cAMP mimic the effects of catecholamines on excitation-contraction coupling in frog atrial fibers

H. Lester, J. Nerbonne, S. Richard, 1985, Pflügers Archiv.

Suprachiasmatic Nucleus Resting Membrane Potential of Neurons in Rat

G. Govindaiah, C. Pennartz, J. Nerbonne, 2015 .

Caged compounds: tools for illuminating neuronal responses and connections

J. Nerbonne, 1996, Current Opinion in Neurobiology.

Combined deep microRNA and mRNA sequencing identifies protective transcriptomal signature of enhanced PI3Kα signaling in cardiac hypertrophy.

M. Lovett, J. Nerbonne, Kai-Chien Yang, 2012, Journal of molecular and cellular cardiology.

Mitofusin 2-Containing Mitochondrial-Reticular Microdomains Direct Rapid Cardiomyocyte Bioenergetic Responses Via Interorganelle Ca2+ Crosstalk

J. Nerbonne, G. Dorn, G. Csordás, 2012, Circulation research.

Voltage-gated sodium currents in cerebellar Purkinje neurons: functional and molecular diversity

Joseph L. Ransdell, J. Nerbonne, 2018, Cellular and Molecular Life Sciences.

Cloning and expression of a rat cardiac delayed rectifier potassium channel.

D. Clapham, J. Nerbonne, M. Paulmichl, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Circulating long noncoding RNA DKFZP434I0714 predicts adverse cardiovascular outcomes in patients with end-stage renal disease.

J. Nerbonne, J. Gu, Kai-Chien Yang, 2019, International journal of cardiology.

Regional Differences in mRNA and lncRNA Expression Profiles in Non-Failing Human Atria and Ventricles

J. Nerbonne, S. Matkovich, Eric K. Johnson, 2018, Scientific Reports.

Intracellular FGF14 (iFGF14) Is Required for Spontaneous and Evoked Firing in Cerebellar Purkinje Neurons and for Motor Coordination and Balance

Joseph L. Ransdell, J. Nerbonne, D. Ornitz, 2015, The Journal of Neuroscience.

Notch-Mediated Epigenetic Regulation of Voltage-Gated Potassium Currents.

J. Nerbonne, W. Wang, R. Dı́az-Trelles, 2016, Circulation research.

A‐type K+ channels encoded by Kv4.2, Kv4.3 and Kv1.4 differentially regulate intrinsic excitability of cortical pyramidal neurons

A. Burkhalter, J. Nerbonne, Y. Carrasquillo, 2012, The Journal of physiology.

Liquid Crystalline Solvents as Mechanistic Probes. IV. The Influence of Ordered Media on the Norrish Type II Photoprocesses in α‐Diketones

J. Nerbonne, R. Weiss, 1979 .

Generation of Human Striatal Neurons by MicroRNA-Dependent Direct Conversion of Fibroblasts

Matheus B. Victor, Michelle Richner, Andrew S. Yoo, 2014, Neuron.

Fragile dynamics enable diverse genomic determinants to influence arrhythmia propensity

J. Nerbonne, R. Iyengar, E. Sobie, 2017, bioRxiv.

Presenilins Upregulate Functional K+Channel Currents in Mammalian Cells

J. Nerbonne, A. Goate, Sacha A. Malin, 1998, Neurobiology of Disease.

Enhanced cardiac PI3Kα signalling mitigates arrhythmogenic electrical remodelling in pathological hypertrophy and heart failure.

J. Nerbonne, Kai-Chien Yang, J. McMullen, 2012, Cardiovascular research.

Enhanced cardiac PI 3 K a signalling mitigates arrhythmogenic electrical remodelling in pathological hypertrophy and heart failure

J. Nerbonne, Kai-Chien Yang, J. McMullen, 2012 .

Homeostatic regulation of electrical excitability in physiological cardiac hypertrophy

J. Nerbonne, Céline Marionneau, Kai-Chien Yang, 2010, The Journal of physiology.

Mesp1 coordinately regulates cardiovascular fate restriction and epithelial-mesenchymal transition in differentiating ESCs.

Wei Wang, Ellen M Langer, Michael Kyba, 2008, Cell stem cell.

Distinct Firing Properties of Vasoactive Intestinal Peptide-Expressing Neurons in the Suprachiasmatic Nucleus

J. Nerbonne, E. Herzog, T. Hermanstyne, 2016, Journal of biological rhythms.

Elimination of the Fast Transient in Superior Cervical Ganglion Neurons with Expression of KV4.2W362F: Molecular Dissection ofIA

J. Nerbonne, Sacha A. Malin, 2000, The Journal of Neuroscience.

Loss-of-function DNA sequence variant in the CLCNKA chloride channel implicates the cardio-renal axis in interindividual heart failure risk variation

Derek J Van Booven, Muredach P Reilly, Hakon Hakonarson, 2011, Proceedings of the National Academy of Sciences.

Outward K+ current densities and Kv1.5 expression are reduced in chronic human atrial fibrillation.

J. Nerbonne, J. Trimmer, D. V. Van Wagoner, 1997, Circulation research.

MicroRNA-133a Protects Against Myocardial Fibrosis and Modulates Electrical Repolarization Without Affecting Hypertrophy in Pressure-Overloaded Adult Hearts

J. Nerbonne, G. Condorelli, G. Dorn, 2010, Circulation research.

Genetic Manipulation of Cardiac K+ Channel Function in Mice: What Have We Learned, and Where Do We Go From Here?

J. Nerbonne, T. Schwarz, D. Escande, 2001, Circulation research.

Elimination of the transient outward current and action potential prolongation in mouse atrial myocytes expressing a dominant negative Kv4 α subunit

J. Nerbonne, H. Xu, Huilin Li, 1999, The Journal of physiology.

CHAPTER 61 – Molecular Mechanisms of Atrial Fibrillation

J. Nerbonne, D. R. Wagoner, 2001 .

Molecular basis of electrical remodeling in atrial fibrillation.

J. Nerbonne, D. V. Van Wagoner, D. R. Wagoner, 2000, Journal of molecular and cellular cardiology.

Mccarthy and Jeanne M. Nerbonne Currents and Human Atrial Fibrillation 2+ Atrial L-type Ca

J. Nerbonne, S. Rossie, A. Pond, 1999 .

The perplexing complexity of cardiac arrhythmias: beyond electrical remodeling.

R. Barr, M. Spach, J. Nerbonne, 2005, Heart rhythm.

Gender Differences in Electrophysiological Gene Expression in Failing and Non-Failing Human Hearts

J. Nerbonne, I. Efimov, C. Ambrosi, 2013, PloS one.

Molecular Analysis of Voltage-Gated K+ Channel Diversity and Functioning in the Mammalian Heart

J. Nerbonne, 2011 .

Molecular Mechanisms Controlling Functional Voltage-Gated K+Channel Diversity and Expression in the Mammalian Heart

J. Nerbonne, 2001 .

Potential molecular basis of different physiological properties of the transient outward K+ current in rabbit and human atrial myocytes.

S Nattel, J. Nerbonne, S. Nattel, 1999, Circulation research.

Rapid ventricular repolarization in rodents: electrocardiographic manifestations, molecular mechanisms, and clinical insights.

J. Nerbonne, I. Gussak, B. Chaitman, 2000, Journal of electrocardiology.

Understanding Circadian Mechanisms of Sudden Cardiac Death: A Report From the National Heart, Lung, and Blood Institute Workshop, Part 2: Population and Clinical Considerations

F. Scheer, J. Nerbonne, C. Garnett, 2021, Circulation. Arrhythmia and electrophysiology.

The FGF14F145S Mutation Disrupts the Interaction of FGF14 with Voltage-Gated Na+ Channels and Impairs Neuronal Excitability

J. Nerbonne, D. Ornitz, F. Laezza, 2007, The Journal of Neuroscience.

FGF14 N-terminal splice variants differentially modulate Nav1.2 and Nav1.6-encoded sodium channels

J. Nerbonne, A. M. Rush, S. Dib-Hajj, 2009, Molecular and Cellular Neuroscience.

FGF14 regulates the intrinsic excitability of cerebellar Purkinje neurons

J. Nerbonne, V. Shakkottai, Lin Xu, 2009, Neurobiology of Disease.

Proteomic analysis of native cerebellar iFGF14 complexes

J. Nerbonne, Céline Marionneau, N. Nukina, 2016, Channels.

Mechanisms of noncovalent β subunit regulation of NaV channel gating

J. Nerbonne, Jonathan R. Silva, Z. Varga, 2017, The Journal of general physiology.

Interdependent Roles for Accessory KChIP2, KChIP3, and KChIP4 Subunits in the Generation of Kv4-Encoded IA Channels in Cortical Pyramidal Neurons

J. Nerbonne, Aaron J. Norris, Nicholas C. Foeger, 2010, The Journal of Neuroscience.

Molecular physiology of ion channels that control cardiac repolarization

J. Nerbonne, R. Kass, 2005 .

Molecular, Cellular and Functional Changes in the Retinas of Young Adult Mice Lacking the Voltage-Gated K+ Channel Subunits Kv8.2 and K2.1

Livia S. Carvalho, J. Nerbonne, D. Hunt, 2021, International journal of molecular sciences.

Kv12-Encoded K+ Channels Drive the Day-Night Switch in the Repetitive Firing Rates of SCN Neurons

J. Nerbonne, T. Jegla, E. Herzog, 2023, bioRxiv.

Palmitate attenuates myocardial contractility through augmentation of repolarizing Kv currents.

J. Nerbonne, T. Flagg, C. Nichols, 2010, Journal of molecular and cellular cardiology.

Dual Transgene Expression in Murine Cerebellar Purkinje Neurons by Viral Transduction In Vivo

J. Nerbonne, D. Ornitz, Marie K. Bosch, 2014, PloS one.

The Role of the Voltage-Gated Potassium Channel Proteins Kv8.2 and Kv2.1 in Vision and Retinal Disease: Insights from the Study of Mouse Gene Knock-Out Mutations

David M. Hunt, Nathan S. Hart, Livia S. Carvalho, 2019, eNeuro.

Myocardial K+ Channels: Primary Determinants of Action Potential Repolarization

J. Nerbonne, Noriko Niwa, 2009 .

Molecular Diversity of Ion Channels in the Mouse Heart

J. Nerbonne, Jeanne M. Nerbonne, 2003 .

Targeted Deletion of Kv4.2 Eliminates Ito,f and Results in Electrical and Molecular Remodeling, With No Evidence of Ventricular Hypertrophy or Myocardial Dysfunction

J. Nerbonne, T. Schwarz, Céline Marionneau, 2005, Circulation research.

Voltage-gated sodium currents in cerebellar Purkinje neurons: functional and molecular diversity

Joseph L. Ransdell, J. Nerbonne, 2018, Cellular and Molecular Life Sciences.

Kv4.2 potassium channels segregate to extrasynaptic domains and influence intrasynaptic NMDA receptor NR2B subunit expression

J. Nerbonne, A. Jeromin, F. Ferraguti, 2012, Brain Structure and Function.

New photoactivatable cyclic nucleotides produce intracellular jumps in cyclic AMP and cyclic GMP concentrations

H. Lester, J. Nerbonne, S. Richard, 1984, Nature.

Differential expression of voltage-gated calcium channels in identified visual cortical neurons

A. Burkhalter, J. Nerbonne, J. Solomon, 1991, Neuron.

Alpha 1-adrenergic agonists selectively suppress voltage-dependent K+ current in rat ventricular myocytes.

J. Nerbonne, M. Apkon, Michael Apkon, 1988, Proceedings of the National Academy of Sciences of the United States of America.

Patch‐Clamp Recordings from Isolated Cardiac Myocytes

J. Nerbonne, Kai-Chien Yang, Wei Wang, 2013 .

Differential Expression and Remodeling of Transient Outward Potassium Currents in Human Left Ventricles

J. Nerbonne, Kathryn A. Yamada, E. Dranoff, 2018, Circulation. Arrhythmia and electrophysiology.

Mouse models of arrhythmogenic cardiovascular disease: challenges and opportunities.

Jeanne M Nerbonne, J. Nerbonne, 2014, Current opinion in pharmacology.

Understanding Circadian Mechanisms of Sudden Cardiac Death: A Report From the National Heart, Lung, and Blood Institute Workshop, Part 1: Basic and Translational Aspects

F. Scheer, J. Nerbonne, C. Garnett, 2021, Circulation. Arrhythmia and electrophysiology.

Proteolytic Processing of HCN2 and Co-assembly with HCN4 in the Generation of Cardiac Pacemaker Channels*

J. Nerbonne, B. Ye, 2009, The Journal of Biological Chemistry.

Hyperpolarization‐activated currents in isolated superior colliculus‐projecting neurons from rat visual cortex.

J. Nerbonne, J. Solomon, J S Solomon, 1993, The Journal of physiology.

Attenuation of I(K,slow1) and I(K,slow2) in Kv1/Kv2DN mice prolongs APD and QT intervals but does not suppress spontaneous or inducible arrhythmias.

J. Nerbonne, G. Mitchell, G. Koren, 2004, American journal of physiology. Heart and circulatory physiology.

Characterization of SEMA3A-Encoded Semaphorin as a Naturally Occurring Kv4.3 Protein Inhibitor and its Contribution to Brugada Syndrome

J. Nerbonne, P. Schwartz, A. Wilde, 2014, Circulation research.

Myocardial potassium channels: electrophysiological and molecular diversity.

J. Nerbonne, D. Barry, D. Barry, 1996, Annual review of physiology.

Genetic perturbation of postsynaptic activity regulates synapse elimination in developing cerebellum

G. Feng, J. Sanes, J. Nerbonne, 2009, Proceedings of the National Academy of Sciences.

Stabilization of Kv4 protein by the accessory K+ channel interacting protein 2 (KChIP2) subunit is required for the generation of native myocardial fast transient outward K+ currents

J. Nerbonne, Wei Wang, Nicholas C. Foeger, 2013, The Journal of physiology.

Distinct Transient Outward Potassium Current (Ito) Phenotypes and Distribution of Fast-inactivating Potassium Channel Alpha Subunits in Ferret Left Ventricular Myocytes

J. Nerbonne, J. Trimmer, H. Strauss, 1999, The Journal of general physiology.

Identification of structures for ion channel kinetic models

J. Nerbonne, J. Moreno, Jonathan R. Silva, 2021, bioRxiv.

Dispersion of repolarization and refractoriness are determinants of arrhythmia phenotype in transgenic mice with long QT

J. Nerbonne, G. Salama, B. London, 2007, The Journal of physiology.

Mechanical dysfunction induced by a hypertrophic cardiomyopathy mutation is the primary driver of cellular adaptation

Sarah R. Clippinger, J. Nerbonne, M. Greenberg, 2020, bioRxiv.

Training the Next Generation of Translational Cardiovascular Investigators

J. Nerbonne, D. Mann, 2016, JACC: Basic to Translational Science.

Functional consequences of elimination of i(to,f) and i(to,s): early afterdepolarizations, atrioventricular block, and ventricular arrhythmias in mice lacking Kv1.4 and expressing a dominant-negative Kv4 alpha subunit.

J. Nerbonne, B. London, H. Li, 2000, Circulation research.

Photoinduced removal of nifedipine reveals mechanisms of calcium antagonist action on single heart cells

H. Lester, J. Nerbonne, A. Gurney, 1985, The Journal of general physiology.

Design and application of photolabile intracellular probes.

J. Nerbonne, 1986, Society of General Physiologists series.

IA Channels

J. Nerbonne, Y. Carrasquillo, Yarimar Carrasquillo, 2014, The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry.

Differential Expression of IA Channel Subunits Kv4.2 and Kv4.3 in Mouse Visual Cortical Neurons and Synapses

A. Burkhalter, J. Nerbonne, Y. Gonchar, 2006, The Journal of Neuroscience.

Voltage-gated potassium channels (Kv) in GtoPdb v.2023.1

J. Nerbonne, B. Rudy, J. Trimmer, 2023, IUPHAR/BPS Guide to Pharmacology CITE.

Role of Heteromultimers in the Generation of Myocardial Transient Outward K+ Currents

J. Nerbonne, K. Rhodes, J. Trimmer, 2002, Circulation research.

Developmental analysis reveals mismatches in the expression of K+ channel alpha subunits and voltage-gated K+ channel currents in rat ventricular myocytes

J. Nerbonne, J. Trimmer, D. Mckinnon, 1996, The Journal of general physiology.

Differential expression of voltage-gated K+ channel subunits in adult rat heart. Relation to functional K+ channels?

J. Nerbonne, J. Trimmer, J. Merlie, 1995, Circulation Research.

Mechanical dysfunction of the sarcomere induced by a pathogenic mutation in troponin T drives cellular adaptation

Sarah R. Clippinger, J. Nerbonne, M. Greenberg, 2021, The Journal of general physiology.

Modulation of the effects of class Ib antiarrhythmics on cardiac NaV1.5-encoded channels by accessory NaVβ subunits

J. Nerbonne, Jonathan R. Silva, L. Isom, 2021, JCI insight.

The Kv4.2 Potassium Channel Subunit Is Required for Pain Plasticity

J. Nerbonne, T. Schwarz, R. Gereau, 2006, Neuron.

Characterization of two distinct depolarization-activated K+ currents in isolated adult rat ventricular myocytes

J. Nerbonne, M. Apkon, Michael Apkon, 1991, The Journal of general physiology.

Two kinetically distinct components of hyperpolarization‐activated current in rat superior colliculus‐projecting neurons.

J. Nerbonne, J. Solomon, 1993, The Journal of physiology.

Cellular / Molecular Interdependent Roles for Accessory KChIP 2 , KChIP 3 , and KChIP 4 Subunits in the Generation of Kv 4-Encoded I A Channels in Cortical Pyramidal Neurons

J. Nerbonne, Aaron J. Norris, Nicholas C. Foeger, 2018 .

Fibroblast growth factor 14 is an intracellular modulator of voltage‐gated sodium channels

J. Nerbonne, A. Craig, H. Hartmann, 2005, The Journal of physiology.

Proteomic and functional mapping of cardiac NaV1.5 channel phosphorylation sites

R. Pappu, J. Nerbonne, Céline Marionneau, 2021, The Journal of general physiology.

Proteomic and functional mapping of cardiac NaV1.5 channel phosphorylation reveals multisite regulation of surface expression and gating

R. Pappu, J. Nerbonne, Céline Marionneau, 2020, bioRxiv.

C-terminal phosphorylation of NaV1.5 impairs FGF13-dependent regulation of channel inactivation

Cheryl F. Lichti, J. Nerbonne, Céline Marionneau, 2017, The Journal of Biological Chemistry.

Physiology and Molecular Biology of Ion Channels Contributing to Ventricular Repolarization

J. Nerbonne, R. Kass, 2003 .

Regulation of voltage-gated K+ channel expression in the developing mammalian myocardium.

J. Nerbonne, 1998, Journal of neurobiology.

FGF14 localization and organization of the axon initial segment

J. Nerbonne, D. Ornitz, Maolei Xiao, 2013, Molecular and Cellular Neuroscience.

Acute Knockdown of Kv4.1 Regulates Repetitive Firing Rates and Clock Gene Expression in the Suprachiasmatic Nucleus and Daily Rhythms in Locomotor Behavior

J. Nerbonne, E. Herzog, T. Hermanstyne, 2017, eNeuro.

Calcium channels are 'unblocked' within a few milliseconds after photoremoval of nifedipine.

J. Nerbonne, S. Richard, J. Nargeot, 1985, Journal of molecular and cellular cardiology.

Augmentation of Kv4.2-encoded Currents by Accessory Dipeptidyl Peptidase 6 and 10 Subunits Reflects Selective Cell Surface Kv4.2 Protein Stabilization*

J. Nerbonne, Aaron J. Norris, Nicholas C. Foeger, 2012, The Journal of Biological Chemistry.

Heterogeneous Expression of Voltage‐Gated Potassium Channels in the Heart: Roles in Normal Excitation and Arrhythmias

Weinong Guo, Jeanne M Nerbonne, J. Nerbonne, 2002, Journal of cardiovascular electrophysiology.

Mechanisms linking short- and long-term electrical remodeling in the heart .....is it a stretch?

J. Nerbonne, S. Marrus, 2008, Channels.

Substituted benzyl acetates: a new class of compounds that reduce gap junctional conductance by cytoplasmic acidification

J. Nerbonne, D. Spray, M. Bennett, 1984, The Journal of cell biology.

Polycystin 2 is increased in disease to protect against stress-induced cell death

J. Nerbonne, L. Cantley, H. J. Chung, 2020, Scientific Reports.

Selective elimination of IK,slow1 in mouse ventricular myocytes expressing a dominant negative Kv1.5α subunit

J. Nerbonne, Kathryn A. Yamada, Huilin Li, 2004 .

Blockade of Ca2+ and K+ currents in bag cell neurons of Aplysia californica by dihydropyridine Ca2+ antagonists

J. Nerbonne, A. Gurney, 1987, The Journal of neuroscience : the official journal of the Society for Neuroscience.

Direct Evidence for the Inhibition of Platelet Aggregation and Release by Intracellular Cyclic AMP Produced with a New Photoactivatable Derivative

J. Nerbonne, J. Nargeot, D. Blache, 1986, Thrombosis and Haemostasis.

Microarray Analysis Reveals Complex Remodeling of Cardiac Ion Channel Expression With Altered Thyroid Status: Relation to Cellular and Integrated Electrophysiology

J. Nerbonne, J. Léger, D. Escande, 2003, Circulation research.

A novel type of depolarization-activated K+ current in isolated adult rat atrial myocytes.

J. Nerbonne, W. Boyle, 1991, The American journal of physiology.

Illuminating approaches to cellular physiology

J. Nerbonne, R. Bloch, R. Rakowski, 1995, Trends in Neurosciences.

Concordant expression of KChIP2 mRNA, protein and transient outward current throughout the canine ventricle

J. Nerbonne, D. Mckinnon, B. Rosati, 2003, The Journal of physiology.

Cyclic-AMP-dependent phosphorylation modulates the stereospecific activation of cardiac Ca channels by Bay K 8644

J. Nerbonne, P. Lory, F. Tiaho, 1990, Pflügers Archiv.

Regional upregulation of Kv2.1-encoded current, IK,slow2, in Kv1DN mice is abolished by crossbreeding with Kv2DN mice.

Jeanne M Nerbonne, J. Nerbonne, G. Koren, 2003, American journal of physiology. Heart and circulatory physiology.

Calmodulin Kinase II Inhibition Shortens Action Potential Duration by Upregulation of K+ Currents

J. Hell, J. Nerbonne, Céline Marionneau, 2006, Circulation research.

Electrophysiological Experiments With Photoisomerizable Cholinergic Compounds: Review and Progress Report *

H. Lester, J. Nerbonne, M. M. Nass, 1980, Annals of the New York Academy of Sciences.

Expression environment determines K+ current properties: Kv1 and Kv4 α-subunit-induced K+ currents in mammalian cell lines and cardiac myocytes

J. Nerbonne, Karla R. Petersen, 1999, Pflügers Archiv.

The Role of the Voltage-Gated Potassium Channel Proteins Kv8.2 and Kv2.1 in Vision and Retinal Disease: Insights from the Study of Mouse Gene Knock-Out Mutations

Livia S. Carvalho, J. Nerbonne, D. Hunt, 2019, eNeuro.

Molecular Heterogeneity of the Voltage-Gated Fast Transient Outward K+ Current, IAf, in Mammalian Neurons

J. Nerbonne, Sacha A. Malin, 2001, The Journal of Neuroscience.

Three kinetically distinct Ca2+-independent depolarization-activated K+ currents in callosal-projecting rat visual cortical neurons.

J. Nerbonne, R. Locke, Rachel E. Locke, 1997, Journal of neurophysiology.

Role of voltage-gated K+ currents in mediating the regular-spiking phenotype of callosal-projecting rat visual cortical neurons.

J. Nerbonne, J M Nerbonne, R E Locke, 1997, Journal of neurophysiology.

Notch-Mediated Epigenetic Regulation of Voltage-Gated Potassium Currents

J. Nerbonne, R. Dı́az-Trelles, S. Rentschler, 2016 .

Kv12-encoded K+ channels drive the day-night switch in the repetitive firing rates of SCN neurons.

J. Nerbonne, T. Jegla, E. Herzog, 2023, The Journal of general physiology.

Controlling the Traffic to Keep the Beat: Targeting of Myocardial Sodium Channels.

J. Nerbonne, 2021, Circulation Research.

Cardiac Mechano-Gated Ion Channels and Arrhythmias.

J. Nerbonne, P. Kohl, R. Peyronnet, 2016, Circulation research.

Potassium currents in the heart: functional roles in repolarization, arrhythmia and therapeutics

J. Nerbonne, J. Weiss, M. Sanguinetti, 2017, The Journal of physiology.

Proteomic analysis of native cerebellar iFGF14 complexes

J. Nerbonne, Céline Marionneau, N. Nukina, 2016, Channels.

Determinants of iFGF13-mediated regulation of myocardial voltage-gated sodium (NaV) channels in mouse.

J. Nerbonne, C. Lindskog, Céline Marionneau, 2023, The Journal of general physiology.

C-terminal phosphorylation of NaV1.5 impairs FGF13-dependent regulation of channel inactivation

J. Nerbonne, Céline Marionneau, F. Charpentier, 2017, The Journal of Biological Chemistry.

Mass spectrometry-based identification of native cardiac Nav1.5 channel α subunit phosphorylation sites.

J. Nerbonne, Céline Marionneau, F. Charpentier, 2012, Journal of proteome research.

VIP and secretin augment cardiac L-type calcium channel currents in isolated adult rat ventricular myocytes

J. Nerbonne, F. Tiaho, 1996, Pflügers Archiv.

Calcium-independent depolarization-activated potassium currents in superior colliculus-projecting rat visual cortical neurons.

J. Nerbonne, J M Nerbonne, J L Albert, 1995, Journal of neurophysiology.

ER71 specifies Flk-1+ hemangiogenic mesoderm by inhibiting cardiac mesoderm and Wnt signaling.

J. Nerbonne, D. Lim, Kyunghee Choi, 2012, Blood.

Mesp1 coordinately regulates cardiovascular fate restriction and epithelial-mesenchymal transition in differentiating ESCs.

Ellen M. Langer, M. Kyba, J. Nerbonne, 2008, Cell stem cell.

Proteolytic Processing of HCN2 and Co-assembly with HCN4 in the Generation of Cardiac Pacemaker Channels*

J. Nerbonne, B. Ye, 2009, The Journal of Biological Chemistry.

Development of the fast, transient outward K+ current in embryonic sympathetic neurones

J. Nerbonne, H. Rayburn, A. Gurney, 1986, Brain Research.

Results Expression of Kv 4 . 2 and Kv 4 . 3 in Adult Mouse Ventricles

J. Nerbonne, K. Rhodes, J. Trimmer, 2002 .

Intrinsic mechanisms in the gating of resurgent Na+ currents

Joseph L. Ransdell, J. Nerbonne, J. Moreno, 2021, bioRxiv.

Loss of Intracellular Fibroblast Growth Factor 14 (iFGF14) Increases the Excitability of Mature Hippocampal and Cortical Pyramidal Neurons

Joseph L. Ransdell, J. Nerbonne, Marie K. Bosch, 2024, bioRxiv.

"Caged" phenylephrine: development and application to probe the mechanism of alpha-receptor-mediated vasoconstriction.

J. Nerbonne, W. Boyle, S. Muralidharan, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Molecular Dissection of IA in Cortical Pyramidal Neurons Reveals Three Distinct Components Encoded by Kv4.2, Kv4.3, and Kv1.4 α-Subunits

J. Nerbonne, Aaron J. Norris, 2010, The Journal of Neuroscience.