J. Seidman

J. Seidman, A. Robling, C. Seidman, 2013, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

The T-Box transcription factor Tbx5 is required for the patterning and maturation of the murine cardiac conduction system

J. Seidman, B. Bruneau, D. Roden, 2004, Development.

Summary The T-Box transcription factor Tbx 5 is required for the patterning and maturation of the murine cardiac conduction system

J. Seidman, B. Bruneau, D. Roden, 2004 .

Early post-zygotic mutations contribute to congenital heart disease

K. B. Manheimer, W. Chung, J. Seidman, 2019, bioRxiv.

SARS-CoV-2 entry factors are highly expressed in nasal epithelial cells together with innate immune genes

Masahiro Yoshida, Fabian J. Theis, Oliver Eickelberg, 2020, Nature Medicine.

Nucleotide sequences of the human and mouse atrial natriuretic factor genes.

K. A. Klein, J. Seidman, C. Seidman, 1984, Science.

THSD1 (Thrombospondin Type 1 Domain Containing Protein 1) Mutation in the Pathogenesis of Intracranial Aneurysm and Subarachnoid Hemorrhage

J. Seidman, D. Milewicz, C. Seidman, 2016, Stroke.

Functional Characterization of a Novel Mutation in NKX2-5 Associated With Congenital Heart Disease and Adult-Onset Cardiomyopathy

Milena B. Furtado, Mauro W. Costa, N. Rosenthal, 2013, Circulation. Cardiovascular genetics.

A polymorphic modifier gene alters the hypertrophic response in a murine model of familial hypertrophic cardiomyopathy.

J. Seidman, D. Fatkin, C. Seidman, 2001, Journal of molecular and cellular cardiology.

Eya4 regulation of Na+/K+-ATPase is required for sensory system development in zebrafish

L. Zon, J. Seidman, C. Seidman, 2008, Development.

Eya4-deficient mice are a model for heritable otitis media.

J. Seidman, R. Eavey, M. Liberman, 2008, The Journal of clinical investigation.

Mutation in the transcriptional coactivator EYA4 causes dilated cardiomyopathy and sensorineural hearing loss

L. Zon, J. Seidman, A. Mungall, 2005, Nature Genetics.

Every-3-Week Paclitaxel for Ovarian Cancer

J. Seidman, J. Ware, 2016 .

Abnormal Left-Hemispheric Sulcal Patterns Correlate with Neurodevelopmental Outcomes in Subjects with Single Ventricular Congenital Heart Disease.

J. Seidman, P. Grant, D. Wypij, 2019, Cerebral cortex.

Pathway Genes in Familial Cases of Intracranial Aneurysm β Sequencing of TGF-Print

J. Seidman, D. Milewicz, C. Seidman, 2009 .

Sequencing of TGF-beta pathway genes in familial cases of intracranial aneurysm.

J. Seidman, D. Milewicz, C. Seidman, 2009, Stroke.

J. Seidman, T. Kurtz, C. Seidman, 2011, Physiological genomics.

Different Transcriptomic Response to T. cruzi Infection in hiPSC-Derived Cardiomyocytes From Chagas Disease Patients With and Without Chronic Cardiomyopathy

J. Seidman, J. Krieger, C. Seidman, 2022, Frontiers in Cellular and Infection Microbiology.

Pheochromocytoma-Induced Cardiomyopathy is Modulated by the Synergistic Effects of Cell-Secreted Factors

J. Seidman, E. Edelman, A. Baker, 2009, Circulation. Heart failure.

Robust identification of deletions in exome and genome sequence data based on clustering of Mendelian errors

K. B. Manheimer, W. Chung, J. Seidman, 2017, bioRxiv.

Genetic Studies of Hypertrophic Cardiomyopathy in Singaporeans Identify Variants in TNNI3 and TNNT2 That Are Common in Chinese Patients

J. Seidman, S. Cook, A. de Marvao, 2020, Circulation. Genomic and precision medicine.

Recombination events that activate, diversify, and delete immunoglobulin genes.

J. Seidman, P. Leder, E. E. Max, 1981, Cold Spring Harbor symposia on quantitative biology.

Cytoskeletal Changes in the Brains of Mice Lacking Calcineurin Aα

J. Seidman, H. Potter, U. Kayyali, 1997, Journal of neurochemistry.

Dynamic tissue-speci c H2Bub1 is required for human and mouse cardiogenesis

J. Seidman, C. Seidman, Sidi Chen, 2022 .

Regulation of chamber-specific gene expression in the developing heart by Irx4.

J. Seidman, B. Bruneau, C. Cepko, 1999, Science.

Exercise Training Improves Cardiac Function and Attenuates Arrhythmia in Cpvt Mice Experimental Protocol

J. Seidman, C. Seidman, M. Eldar, 2022 .

Myocardial Iron Deficiency and Mitochondrial Dysfunction in Advanced Heart Failure in Humans

J. Seidman, C. Seidman, J. Seubert, 2022, Journal of the American Heart Association.

Cardiac-enriched BAF chromatin-remodeling complex subunit Baf60c regulates gene expression programs essential for heart development and function

J. Seidman, J. Rossant, B. Bruneau, 2017, Biology Open.

CLINICAL STUDIES Hypertrophic Cardiomyopathy Development of Left Ventricular Hypertrophy in Adults With Hypertrophic Cardiomyopathy Caused by Cardiac Myosin-Binding Protein C Gene Mutations

J. Seidman, B. Maron, C. Seidman, 2001 .

Alterations of Phospholamban Function Can Exhibit Cardiotoxic Effects Independent of Excessive Sarcoplasmic Reticulum Ca2+-ATPase Inhibition

Ferhaan Ahmad, J. Schmitt, J. Seidman, 2009, Circulation.

Human iPSC-CMs and in-silico technologies define mechanisms and accelerate targeted pharmacogenetics in hypertrophic cardiomyopathy

J. Seidman, B. Rodríguez, A. Bueno-Orovio, 2022, bioRxiv.

BET Bromodomain Proteins Regulate Transcriptional Reprogramming in Genetic Dilated Cardiomyopathy

Saptarsi M. Haldar, Michael A. Burke, J. Seidman, 2020, bioRxiv.

An Ia-positive mouse T-cell clone is functional in presenting antigen to other T cells

J. Seidman, L. Glimcher, C. Murre, 2004, Immunogenetics.

Detection of Cell Proliferation Markers by Immunofluorescence Staining and Microscopy Imaging in Paraffin‐Embedded Tissue Sections

J. Seidman, C. Seidman, S. Eminaga, 2016, Current protocols in molecular biology.

A Novel Role for CSRP1 in a Lebanese Family with Congenital Cardiac Defects

J. Seidman, C. Seidman, N. El-Hachem, 2017, Front. Genet..

A Novel Role for CSRP1 in a Lebanese Family with Congenital Cardiac Defects

J. Seidman, C. Seidman, N. El-Hachem, 2017, Front. Genet..

Expression of H-2Dd and H-2Ld mouse major histocompatibility antigen genes in L cells after DNA-mediated gene transfer.

J. Seidman, G. Evans, E. Appella, 1983, Journal of immunology.

A dominant Stargardt's macular dystrophy locus maps to chromosome 13q34.

J. Seidman, L. Donoso, C. Seidman, 1994, Archives of ophthalmology.

LAMP2 Cardiomyopathy: Consequences of Impaired Autophagy in the Heart

J. Seidman, W. Roberts, B. Maron, 2021, Journal of the American Heart Association.

Clinical Outcome and Phenotypic Expression in LAMP 2 Cardiomyopathy

J. Seidman, J. Saul, W. Roberts, 2009 .

FUNCTIONAL CHARACTERIZATION OF A NOVEL MUTATION IN NKX 2-5 ASSOCIATED WITH CONGENITAL HEART DISEASE AND ADULT-ONSET CARDIOMYOPATHY . Costa : NKX 2-5 mutation in familial DCM

Milena B. Furtado, Mauro W. Costa, J. Seidman, 2015 .

The Role of the L-Type Ca2+ Channel in Altered Metabolic Activity in a Murine Model of Hypertrophic Cardiomyopathy

Victoria P. A. Johnstone, J. Seidman, C. Seidman, 2016, JACC. Basic to translational science.

Myosin Sequestration Regulates Sarcomere Function, Cardiomyocyte Energetics, and Metabolism, Informing the Pathogenesis of Hypertrophic Cardiomyopathy

J. F. Staples, E. Ashley, S. Colan, 2020, Circulation.

An enhancer element and a functional cyclic AMP-dependent protein kinase are required for expression of adrenocortical 21-hydroxylase.

J. Seidman, M. Szyf, B. Schimmer, 1988, The Journal of biological chemistry.

Compound and double mutations in patients with hypertrophic cardiomyopathy: implications for genetic testing and counselling

J. Seidman, C. Seidman, C. Semsarian, 2005, Journal of Medical Genetics.

Constitutively active AMP kinase mutations cause glycogen storage disease mimicking hypertrophic cardiomyopathy.

J. Seidman, C. Seidman, A. Perez-Atayde, 2002, The Journal of clinical investigation.

Increased glycogen stores due to gamma-AMPK overexpression protects against ischemia and reperfusion damage.

J. Seidman, D. Freimark, C. Seidman, 2008, Biochemical pharmacology.

Electrophysiologic Characteristics of Accessory Atrioventricular Connections in an Inherited Form of Wolff‐Parkinson‐White Syndrome

J. Seidman, D. Fatkin, J. Dimarco, 1999, Journal of cardiovascular electrophysiology.

IL-12 is required for differentiation of pathogenic CD8+ T cell effectors that cause myocarditis.

Ferhaan Ahmad, J. Seidman, C. Seidman, 2003, The Journal of clinical investigation.

Two forms of the T-cell receptor γ protein found on peripheral blood cytotoxic T lymphocytes

J. Seidman, J. Mclean, M. Krangel, 1987, Nature.

Immunodominance is altered in T cell receptor (beta-chain) transgenic mice without the generation of a hole in the repertoire.

J. Seidman, D. Fruman, D. Perkins, 1991, Journal of immunology.

Atrial natriuretic factor: assessment of its structure in atria and regulation of its biosynthesis with volume depletion.

J. Seidman, J. Fallon, C. Seidman, 1986, Journal of molecular and cellular cardiology.

H-2Ld antigen encoded by a recombinant retrovirus genome is expressed on the surface of infected cells

J. Seidman, R. Mulligan, S. Burakoff, 1985, Molecular and cellular biology.

Expression of complement proteins C2 and factor B in transfected L cells.

J. Seidman, H. Colten, J. Strominger, 1985, The Journal of clinical investigation.

Multiple mRNA species with distinct 3′ termini are transcribed from the β2-microglobulin gene

R. R. Robinson, J. Seidman, J. Parnes, 1983, Nature.

Cardiac Myosin-Binding Protein-C Phosphorylation and Cardiac Function

J. Seidman, G. Dorn, C. Seidman, 2005, Circulation research.

Population Prevalence of Premature Truncating Variants in Plakophilin-2 and Association With Arrhythmogenic Right Ventricular Cardiomyopathy: A UK Biobank Analysis

Vassilios J. Bezzerides, J. Seidman, W. Pu, 2022, Circulation. Genomic and precision medicine.

cis modification of the steroid 21-hydroxylase gene prevents its expression in the Y1 mouse adrenocortical tumor cell line.

J. Seidman, M. Szyf, B. Schimmer, 1990, Molecular endocrinology.

&bgr;-Myosin Heavy Chain Variant Val606Met Causes Very Mild Hypertrophic Cardiomyopathy in Mice, but Exacerbates HCM Phenotypes in Mice Carrying Other HCM Mutations

J. Schmitt, J. Seidman, M. Lohse, 2014, Circulation research.

Isotypic exclusion of gamma delta T cell receptors in transgenic mice bearing a rearranged beta-chain gene.

J. Seidman, P. Marrack, J. Kappler, 1988, Science.

Nucleotide-sequence-specific de novo methylation in a somatic murine cell line.

J. Seidman, M. Szyf, B. Schimmer, 1989, Proceedings of the National Academy of Sciences of the United States of America.

Tbx5 Is Required for Avian and Mammalian Epicardial Formation and Coronary Vasculogenesis

O. Elemento, J. Seidman, C. Seidman, 2014, Circulation research.

AKR murine thymic leukemias are from a distinct thymic cell lineage and do not express the beta chain of the T-cell antigen receptor.

J. Seidman, C. Murre, H. Hiai, 1986, Proceedings of the National Academy of Sciences of the United States of America.

T-cell receptor gene rearrangement and expression in human natural killer cells: natural killer activity is not dependent on the rearrangement and expression of T-cell receptor α, β, or γ genes

J. Seidman, J. Strominger, T. Quertermous, 2004, Immunogenetics.

Characterization of a third form of the human T cell receptor gamma/delta

J. Seidman, J. Mclean, J. Strominger, 1988, The Journal of experimental medicine.

Two types of gamma T cell receptors expressed by T cell acute lymphoblastic leukemias

J. Seidman, J. V. van Dongen, J. Dongen, 1987, European journal of immunology.

Characterization of an expressed CDS-associated Ti γ-chain reveals Cγ domain polymorphism

J. Seidman, A. Weiss, S. N. Gettner, 1987, Nature.

Rearrangement and expression of T-cell antigen receptor genes in human T-lymphocyte tumor lines and normal human T-cell clones: evidence for allelic exclusion of Ti beta gene expression and preferential use of a J beta 2 gene segment

J. Seidman, J. Strominger, C. Murre, 1986, Molecular and cellular biology.

T cell receptor (β chain) transgenic mice have selective deficits in γδ T cell subpopulations

J. Seidman, D. Fruman, I. Orme, 1994 .

Control of In Vivo Contraction/Relaxation Kinetics by Myosin Binding Protein C: Protein Kinase A Phosphorylation–Dependent and –Independent Regulation

James O. Mudd, D. Kass, J. Seidman, 2007, Circulation.

Effect of Cardiac Myosin Binding Protein-C on Mechanoenergetics in Mouse Myocardium

J. Seidman, Y. Wang, N. Alpert, 2004, Circulation research.

Dilated cardiomyopathy in homozygous myosin-binding protein-C mutant mice.

D. Kass, J. Seidman, D. Turnbull, 1999, The Journal of clinical investigation.

Reduced cross-bridge dependent stiffness of skinned myocardium from mice lacking cardiac myosin binding protein-C

J. Seidman, N. Alpert, T. Irving, 2004, Molecular and Cellular Biochemistry.

Allospecific and virus-specific cytolytic T lymphocytes are restricted to the N or C1 domain of H-2 antigens expressed on L cells after DNA-mediated gene transfer.

J. Seidman, G. Evans, D. Margulies, 1983, Proceedings of the National Academy of Sciences of the United States of America.

Chromosomal assignment of the mouse kappa light chain genes.

P. D’Eustachio, J. Seidman, L. Leinwand, 1979, Proceedings of the National Academy of Sciences of the United States of America.

Rare genetic variation at transcription factor binding sites modulates local DNA methylation profiles

W. Chung, J. Seidman, A. Sharp, 2020, PLoS genetics.

The expression of major histocompatibility antigens under metallothionein gene promoter control.

J. Seidman, J. Weis, J. G. Seidman, 1985, Journal of immunology.

Cardiac myosin binding protein c phosphorylation is cardioprotective

J. Seidman, C. Seidman, J. Lorenz, 2006, Proceedings of the National Academy of Sciences.

Biochemical and functional analyses of a secreted H-2Ld molecule

J. Seidman, K. Parker, D. Wiley, 1986, Molecular and cellular biology.

The Role of Cardiac Troponin T Quantity and Function in Cardiac Development and Dilated Cardiomyopathy

Stephen H. Smith, Ferhaan Ahmad, J. Seidman, 2008, PloS one.

Hybrid H-2 histocompatibility gene products assign domains recognized by alloreactive T cells.

J. Seidman, G. Evans, D. Margulies, 1983, Proceedings of the National Academy of Sciences of the United States of America.

Cis-acting sequences that modulate atrial natriuretic factor gene expression.

J. Seidman, C. Seidman, D. Wong, 1988, Proceedings of the National Academy of Sciences of the United States of America.

The structure of rat preproatrial natriuretic factor as defined by a complementary DNA clone.

J. Seidman, C. Seidman, R. Graham, 1984, Science.

Functional analysis of myosin missense mutations in familial hypertrophic cardiomyopathy.

J. Seidman, L. Leinwand, C. Seidman, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Metaphase chromosome transfer of introduced selectable markers.

J. Seidman, D. Housman, D. Nelson, 1984, Journal of molecular and applied genetics.

Biosynthesis and secretion of proatrial natriuretic factor by cultured rat cardiocytes.

J. Seidman, J. Fallon, M. N. Margolies, 1985, Science.

Yin Yang 1 Suppresses Dilated Cardiomyopathy and Cardiac Fibrosis Through Regulation of Bmp7 and Ctgf.

J. Seidman, C. Seidman, H. Wakimoto, 2019, Circulation research.

Cardiac expression of the ventricle-specific homeobox gene Irx4 is modulated by Nkx2-5 and dHand.

J. Seidman, B. Bruneau, C. Cepko, 2000, Developmental biology.

Deciphering the super relaxed state of human β-cardiac myosin and the mode of action of mavacamten from myosin molecules to muscle fibers

J. Seidman, J. Spudich, R. Cooke, 2018, Proceedings of the National Academy of Sciences.

A novel mechanism of somatic rearrangement predicted by a human T-cell antigen receptor beta-chain complementary DNA.

K. A. Klein, J. Seidman, C. Murre, 1985, Science.

Polymorphism and complexity of the human DC and murine I‐A alpha chain genes.

C. Auffray, J. Seidman, R. Germain, 1983, The EMBO journal.

Expression of hemolytically active murine fourth component of complement in transfected L cells

J. Seidman, J. Coligan, H. Colten, 1984, Cell.

Molecular map of the murine S region.

J. Seidman, H. Colten, D. Chaplin, 1983, Proceedings of the National Academy of Sciences of the United States of America.

Shared human T cell receptor V beta usage to immunodominant regions of myelin basic protein.

J. Seidman, H. Weiner, D. Hafler, 1990, Science.

Provocative pattern of rearrangements of the genes for the gamma and beta chains of the T-cell receptor in human leukemias.

F. Behm, J. Seidman, T. Quertermous, 1987, Proceedings of the National Academy of Sciences of the United States of America.

Human T cell gamma chain joining regions and T cell development.

J. Seidman, J. V. van Dongen, T. Quertermous, 1987, Journal of immunology.

Immunoglobulin and T-cell receptor gene rearrangement and expression in human lymphoid leukemia cells at different stages of maturation.

T. Waldmann, J. Seidman, B. Haynes, 1986, Proceedings of the National Academy of Sciences of the United States of America.

Cloning and sequence analysis of complementary DNA encoding an aberrantly rearranged human T-cell gamma chain.

J. Seidman, J. Strominger, T. Quertermous, 1986, Proceedings of the National Academy of Sciences of the United States of America.

Measuring the human T cell receptor gamma-chain locus.

J. Seidman, T. Quertermous, W. Strauss, 1987, Science.

Functional gamma chain-associated T cell receptors on cerebrospinal fluid-derived natural killer-like T cell clones

J. Seidman, D. Hafler, S. Ang, 1987, The Journal of experimental medicine.

Pathogenic variants damage cell composition and single cell transcription in cardiomyopathies

Catherine L. Worth, S. Teichmann, J. Seidman, 2022, Science.

CHARACTERIZATION OF A THIRD FORM OF THE HUMAN T CELL RECEPTOR y/S

J. Seidman, J. Mclean, J. Strominger, 2003 .

Functional expression of a cloned I-A beta k gene in B-lymphoma cells.

J. Seidman, L. Glimcher, A. Ben-nun, 1984, Science.

H–2-like genes in the Tla region of mouse chromosome 17

J. Seidman, G. Evans, D. Margulies, 1982, Nature.

Genetic mapping of a human class II antigen beta-chain cDNA clone to the SB region of the HLA complex.

C. Auffray, J. Seidman, J. Strominger, 1983, Proceedings of the National Academy of Sciences of the United States of America.

Acute leukemia expressing the gamma gene product of the putative second T cell receptor.

J. Seidman, R. González-Sarmiento, S. Ang, 1987, The Journal of clinical investigation.

An ancient founder mutation located between ROBO1 and ROBO2 is responsible for increased microtia risk in Amerindigenous populations

J. Seidman, R. Eavey, C. Seidman, 2022, Proceedings of the National Academy of Sciences of the United States of America.

The coming of age of cardiovascular science.

J. Seidman, C. Seidman, 2002, Cold Spring Harbor symposia on quantitative biology.

Subtype‐specific increase in G‐protein α‐subunit mRNA by interleukin 1β

Richard T. Lee, J. Seidman, E. Neer, 1989 .

Proximal Regulatory Domains of Rat Atrial Natriuretic Factor Gene

J. Seidman, C. Seidman, T. Halazonetis, 1991, Circulation.

MYBPC3 Mutations cause Hypertrophic Cardiomyopathy by Dysregulating Myosin: Implications for Therapy

J. Seidman, H. Watkins, C. Seidman, 2018, bioRxiv.

Title : Hypertrophic Cardiomyopathy Mutations in MYBPC 3 Dysregulate Myosin : Implications for Therapy

J. Seidman, H. Watkins, H. Wakimoto, 2018 .

Hypertrophic cardiomyopathy in myosin-binding protein C (MYBPC3) Icelandic founder mutation carriers

Michael A. Burke, J. Seidman, B. Maron, 2020, Open Heart.

Molecular Studies of the Atrial Natriuretic Factor Gene

J. Seidman, C. Seidman, R. Graham, 1985, Hypertension.

Oligoclonal T lymphocytes in the cerebrospinal fluid of patients with multiple sclerosis [published erratum appears in J Exp Med 1988 Jul 1;168(1):459]

J. Seidman, H. Weiner, D. Hafler, 1988, The Journal of experimental medicine.

Atrial natriuretic peptide transcription, storage, and release in rats with myocardial infarction.

J. Seidman, B. Brenner, S. Anderson, 1987, The American journal of physiology.

Familial Hypertrophic Cardiomyopathy Mice Display Gender Differences in Electrophysiological Abnormalities

J. Seidman, C. Seidman, C. Berul, 1997, Journal of Interventional Cardiac Electrophysiology.

Congenital Heart Defects Due to TAF1 Missense Variants.

Jill A. Madden, J. Seidman, C. Brownstein, 2020, Circulation Genomic and Precision Medicine.

Selective Packaging of Host tRNA's by Murine Leukemia Virus Particles Does Not Require Genomic RNA

J. Seidman, J. G. Levin, 1979, Journal of virology.

Effect of polymerase mutations on packaging of primer tRNAPro during murine leukemia virus assembly

J. Seidman, J. G. Levin, 1981, Journal of virology.

Lack of association of secretory component with IgA in J chain-deficient mice.

J. Seidman, D. Waltz, M. Neutra, 1996, Journal of immunology.

Altered hepatic transport of immunoglobulin A in mice lacking the J chain

J. Seidman, C. Seidman, E. E. Max, 1995, The Journal of experimental medicine.

Structure and expression of a mouse major histocompatibility antigen gene , H 2 Ld ( gene cloning / transformation / nucleotide sequence )

J. Seidman, G. Evans, D. Margulies, 2022 .

Neither cardiac mitochondrial DNA variation or copy number contribute to congenital heart disease risk

J. Seidman, Yufeng Shen, D. Bernstein, 2022, The American Journal of Human Genetics.

Class I, II and III major histocompatibility complex gene polymorphisms in BB rats

K. A. Klein, J. Seidman, A. Ben-nun, 1984, Diabetologia.

CD36 overexpression predisposes to arrhythmias but reduces infarct size in spontaneously hypertensive rats: gene expression profile analysis.

J. Seidman, T. Kurtz, C. Seidman, 2012, Physiological genomics.

UBQLN2 mutation causing heterogeneous X‐linked dominant neurodegeneration

J. Seidman, C. Seidman, A. Bick, 2014, Annals of neurology.

Extensive Restriction Site Polymorphism Surrounding a Single Copy I-Aβ Gene

R. R. Robinson, J. Seidman, R. Germain, 1983 .

Genetic analysis of susceptibility to experimental autoimmune encephalomyelitis in a cross between SJL/J and B10.S mice.

J. Seidman, H. Weiner, V. Kuchroo, 1996, Journal of immunology.

Molecular cloning and characterization of cDNA encoding the GTP-binding protein alpha i and identification of a related protein, alpha h.

J. Seidman, E. Neer, J. Smith, 1986, Proceedings of the National Academy of Sciences of the United States of America.

Subtype-specific increase in G-protein alpha-subunit mRNA by interleukin 1 beta.

J. Seidman, E. Neer, K. Bloch, 1989, FEBS letters.

Regulation of murine fetal-placental calcium metabolism by the calcium-sensing receptor.

J. Seidman, C. Seidman, B. Lanske, 1998, The Journal of clinical investigation.

A mutational hot‐spot within an intron of the mouse beta 2‐microglobulin gene.

J. Seidman, J. Parnes, R. Hyman, 1986, The EMBO journal.

The Gene for the ca Subunit of Human Guanine Nucleotide Binding Protein Maps near the Cystic Fibrosis Locus

J. Seidman, E. Neer, C. Morton, 2006 .

Nucleic acid and protein sequences of phosphocholine-binding light chains

J. Seidman, P. Leder, S. Rudikoff, 1981, The Journal of experimental medicine.

Variation in the crossover point of kappa immunoglobulin gene V-J recombination: Evidence from a cryptic gene

J. Seidman, P. Leder, E. E. Max, 1980, Cell.

Progress in familial hypertrophic cardiomyopathy: molecular genetic analyses in the original family studied by Teare.

J. Seidman, H. Watkins, C. Seidman, 1992, British heart journal.

Familial hypocalciuric hypercalcemia and neonatal severe hyperparathyroidism

J. Seidman, E. Brown, C. Seidman, 1995, Pediatric Nephrology.

Adult Hallervorden–Spatz syndrome simulating amyotrophic lateral sclerosis

J. Seidman, C. Seidman, B. McDonough, 2003, Muscle & nerve.

Mouse beta 2-microglobulin cDNA clones: a screening procedure for cDNA clones corresponding to rare mRNAs.

J. Seidman, A. Felsenfeld, E. Appella, 1981, Proceedings of the National Academy of Sciences of the United States of America.

Accelerated Cardiomyopathy in Mice With Overexpression of Cardiac Gsα and a Missense Mutation in the α-Myosin Heavy Chain

J. Seidman, S. Vatner, C. Seidman, 2002 .

Accelerated cardiomyopathy in mice with overexpression of cardiac G(s)alpha and a missense mutation in the alpha-myosin heavy chain.

J. Seidman, S. Vatner, C. Seidman, 2002, Circulation.

Expression of murine 21-hydroxylase in mouse adrenal glands and in transfected Y1 adrenocortical tumor cells.

J. Seidman, J. Smith, D. Chaplin, 1985, Proceedings of the National Academy of Sciences of the United States of America.

Extensive polymorphism surrounding the murine Ia A beta chain gene.

R. R. Robinson, J. Seidman, R. Germain, 1983, Journal of immunology.

A serum protease cleaves proANF into a 14-kilodalton peptide and ANF.

J. Seidman, M. N. Margolies, R. Graham, 1987, The American journal of physiology.

Atrial natriuretic peptide transcription, secretion, and glomerular receptor activity during mineralocorticoid escape in the rat.

J. Seidman, B. Brenner, B. Ballermann, 1986, The Journal of clinical investigation.

Diversity of T-cell antigen receptor V beta gene utilization in advanced human atheroma.

P. Libby, J. Seidman, A. Rosenzweig, 1994, Arteriosclerosis and thrombosis : a journal of vascular biology.

QT Dispersion in α-Myosin Heavy-Chain Familial Hypertrophic Cardiomyopathy Mice

J. Seidman, C. Seidman, C. Berul, 1999, Pediatric Research.

Corrigendum to “Tbx5-dependent rheostatic control of cardiac gene expression and morphogenesis” [Dev. Biol. 297 (2006) 566–586]

J. Seidman, B. Bruneau, R. Henkelman, 2007 .

Genes for two homologous G-protein α subunits map to different human chromosomes

J. Seidman, E. Neer, R. Eddy, 1987, Human Genetics.

Consequences of Pressure Overload on Sarcomere Protein Mutation-Induced Hypertrophic Cardiomyopathy

Richard T. Lee, Ferhaan Ahmad, J. Schmitt, 2003, Circulation.

Rearrangement andExpression ofT-Cell Antigen Receptor Genesin HumanT-Lymphocyte TumorLinesandNormalHumanT-Cell Clones: Evidence forAllelic Exclusion ofTipGeneExpression and Preferential UseofaJ12GeneSegment

J. Seidman, 1986 .

Nonlinkage of the T cell receptor α, β, and γ genes to systemic lupus erythematosus in multiplex families

J. Seidman, Z. Bentwich, P. Schur, 1988 .

Control of expression of histocompatibility antigens (H-2) and beta 2-microglobulin in F9 teratocarcinoma stem cells.

J. Seidman, C. Croce, E. Appella, 1981, Proceedings of the National Academy of Sciences of the United States of America.

Two steroid 21-hydroxylase genes are located in the murine S region

J. Seidman, P. White, D. Chaplin, 1984, Nature.

T cell receptor (TCR) usage determines disease susceptibility in experimental autoimmune encephalomyelitis: studies with TCR V beta 8.2 transgenic mice

J. Seidman, H. Weiner, D. Hafler, 1994, The Journal of experimental medicine.

Recognition of HLA-A2 by cytotoxic T lymphocytes after DNA transfer into human and murine cells.

M. van de Rijn, J. Seidman, H. Spits, 1984, Science.

A De Novo Mutation in α-Tropomyosin That Causes Hypertrophic Cardiomyopathy

J. Seidman, H. Watkins, C. Seidman, 1995 .

Genome-wide association study for Chagas Cardiomyopathy identify a new risk locus on chromosome 18 associated with an immune-related protein and transcriptional signature

J. Seidman, J. Krieger, C. Seidman, 2022, PLoS neglected tropical diseases.

Accelerated Cardiomyopathy in Mice With Overexpression of Cardiac G s (cid:1) and a Missense Mutation in the (cid:1) -Myosin Heavy Chain

J. Seidman, S. Vatner, C. Seidman, 2002 .

Sequencing of TGF- (cid:1) Pathway Genes in Familial Cases of Intracranial Aneurysm

J. Seidman, D. Milewicz, C. Seidman, 2009 .

Multiplexed Single‐Nucleus RNA Sequencing Using Lipid‐Oligo Barcodes

J. Seidman, C. Seidman, Tarsha L Ward, 2022, Current protocols.

Natriuretic Peptide System Gene Variants Are Associated with Ventricular Dysfunction after Coronary Artery Bypass Grafting

J. Seidman, S. Aranki, T. Meitinger, 2009, Anesthesiology.

Regional localization of the human G protein alpha i2 (GNAI2) gene: assignment to 3p21 and a related sequence (GNAI2L) to 12p12-p13.

J. Seidman, E. Neer, C. Morton, 1992, Genomics.

Missense mutation in the pore region of HERG causes familial long QT syndrome.

J. Seidman, C. Seidman, E. Walsh, 1996, Circulation.

Proposal for contemporary screening strategies in families with hypertrophic cardiomyopathy.

Barry J Maron, Christine E Seidman, J. Seidman, 2004, Journal of the American College of Cardiology.

Causes of clinical diversity in human TBX5 mutations.

J. Seidman, C. Seidman, C. Basson, 2002, Cold Spring Harbor symposia on quantitative biology.

Sequestration of virus-specific T cells in the cerebrospinal fluid of a patient with varicella zoster viral meningoencephalitis

J. Seidman, H. Weiner, D. Hafler, 1989, Journal of Neuroimmunology.

Diastolic Dysfunction and Altered Energetics in the a MHC 403 / 1 Mouse Model of Familial Hypertrophic Cardiomyopathy

J. Seidman, C. Seidman, J. Ingwall, 1998 .

A Missense Mutation in Human CHD4 Causes Ventricular Noncompaction by Repressing ADAMTS1-mediated Trabeculation Cessation

J. Seidman, J. Cook, F. Conlon, 2022, bioRxiv.

Mutations in the gene for cardiac myosin-binding protein C and late-onset familial hypertrophic cardiomyopathy.

H Niimura, A E Chudley, J. Seidman, 1998, The New England journal of medicine.

Single-Gene Mutations and Increased Left Ventricular Wall Thickness in the Community The Epidemiology

J. Hirschhorn, J. Seidman, E. Benjamin, 2006 .

Animal models of hypertrophic cardiomyopathy: relevance to human disease

J. Seidman, C. Semsarian, 2005 .

Late-onset primary LVHHCM versus cardiac fabry variant: reply

J. Seidman, B. Maron, C. Seidman, 2002 .

Transcription of mouse kappa chain genes: implications for allelic exclusion.

S. Tonegawa, J. Seidman, P. Leder, 1980, Proceedings of the National Academy of Sciences of the United States of America.

T-cell receptor gene rearrangement and expression in human natural killer cells: natural killer activity is not dependent on the rearrangement and expression of T-cell receptor alpha, beta, or gamma genes.

J. Seidman, J. Strominger, T. Quertermous, 1988, Immunogenetics.

Major histocompatibility complex restriction fragment length polymorphisms define three diabetogenic haplotypes in BB and BBN rats

J. Seidman, J. Buse, D. Chaplin, 1985, The Journal of experimental medicine.

Mavacamten stabilizes a folded-back sequestered super-relaxed state of β-cardiac myosin

J. Seidman, J. Spudich, R. Cooke, 2018, bioRxiv.

Molecular Genetics of Lidocaine-Containing Cardioplegia in the Human Heart During Cardiac Surgery.

J. Seidman, S. Aranki, M. Heydarpour, 2018, The Annals of thoracic surgery.

SARS-CoV-2 entry factors are highly expressed in nasal epithelial cells together with innate immune genes

Fabian J Theis, D. Pe’er, A. Regev, 2020, Nature Medicine.

Assignment of a locus for dominantly inherited venous malformations to chromosome 9p.

J. Seidman, J. Mulliken, M. Vikkula, 1994, Human molecular genetics.

Molecular analysis of 21-hydroxylase gene expression in mouse adrenal cells.

J. Seidman, D. Chaplin, B. Schimmer, 1986, Endocrine research.

Nucleotide sequence analysis of murine 21-hydroxylase genes: mutations affecting gene expression.

J. Seidman, P. White, D. Chaplin, 1986, Proceedings of the National Academy of Sciences of the United States of America.

cis-dominance of rat atrial natriuretic factor gene regulatory sequences in transgenic mice.

J. Seidman, C. Seidman, E. V. Schmidt, 1991, Canadian journal of physiology and pharmacology.

Cloning specific segments of the mammalian genome: bacteriophage lambda containing mouse globin and surrounding gene sequences.

J. Seidman, P. Leder, M. Edgell, 1977, Proceedings of the National Academy of Sciences of the United States of America.

Sarcomere Protein Mutations Cause Dilated Cardiomyopathy

S. Solomon, J. Seidman, C. Seidman, 2001 .

Effects of two familial hypertrophic cardiomyopathy-causing mutations on alpha-tropomyosin structure and function.

J. Seidman, C. Seidman, N. Greenfield, 1997, Biochemistry.

Regional loss of chromosome 6 in two urological malignancies.

J. Richie, J. Seidman, G. Bubley, 1989, Cancer research.

Genetic testing for dilated cardiomyopathy in clinical practice.

Nicole M. Johnson, W. Chung, J. Seidman, 2012, Journal of cardiac failure.

The Transcriptional Signature of Growth in Human Fetal Aortic Valve Development.

J. Seidman, C. Seidman, J. Gorham, 2018, The Annals of thoracic surgery.

Genetic perturbations that reveal tertiary conformation of tRNA precursor molecules

J. Seidman, W. McClain, 1975, Nature.

Clinical implications for molecular genetics of cardiomyopathy

J. Seidman, B. Maron, C. Seidman, 2005 .

Bartter's syndrome and the atrial natriuretic factor gene.

J. Seidman, R. Graham, K. Bloch, 1986, Hypertension.

Damaging variants in FOXI3 cause microtia and craniofacial microsomia

Gloria L. Porras-Hurtado, J. Seidman, R. Eavey, 2022, Genetics in medicine : official journal of the American College of Medical Genetics.

Ablation of lysophosphatidic acid receptor 1 attenuates hypertrophic cardiomyopathy in a mouse model

J. Seidman, L. Leinwand, N. Hübner, 2022, Proceedings of the National Academy of Sciences of the United States of America.

A Murine Model of Holt-Oram Syndrome Defines Roles of the T-Box Transcription Factor Tbx5 in Cardiogenesis and Disease

J. Schmitt, J. Seidman, B. Bruneau, 2001, Cell.

Identification of a putative second T-cell receptor

J. Seidman, J. Mclean, J. Strominger, 1986, Nature.

Isolation and restriction map of the V-J interval of the human T cell receptor γ chain locus

J. Seidman, W. Strauss, V. Fox, 1989 .

Identiﬁcation of genetic loci associated with paralysis, inﬂammation and weight loss in mouse experimental autoimmune encephalomyelitis

J. Seidman, H. Weiner, V. Kuchroo, 2001 .

Cell Receptor ( TCR ) Usage Dete ~ aiines Disease Susceptibility In Experimental Autoimmune Encephalomyelitis : Studies with TCR V / 3 8 . 2 Transgenic Mice

J. Seidman, H. Weiner, R. Sobel, 2003 .

An alpha-cardiac myosin heavy chain gene mutation impairs contraction and relaxation function of cardiac myocytes.

J. Seidman, S. Vatner, C. Seidman, 1999, The American journal of physiology.

Construction and expression of a recombinant antibody-targeted plasminogen activator.

J. Seidman, E. Haber, T. Quertermous, 1987, Proceedings of the National Academy of Sciences of the United States of America.

Autophagy Guided Interventions to Modify the Cardiac Phenotype of Danon Disease.

J. Seidman, C. Seidman, N. Abraham, 2022, Biochemical pharmacology.

Provocative pattern of rearrangements of the genes for the y and f3 chains of the T-cell receptor in human leukemias

F. Behm, J. Seidman, G. Kitchingman, 2022 .

Pathogenesis of Cardiomyopathy Caused by Variants in ALPK3, an Essential Pseudokinase in the Cardiomyocyte Nucleus and Sarcomere

S. Gygi, J. Seidman, J. Paulo, 2022, Circulation.

Effects of Mutant Gene Dosage on Phenotype

J. Seidman, E. Brown, C. Seidman, 2016 .

Mutations in the human Ca(2+)-sensing-receptor gene that cause familial hypocalciuric hypercalcemia.

J. Seidman, E. Brown, M. Brandi, 1995, American journal of human genetics.

Genetics and disease of ventricular muscle.

J. Seidman, D. Fatkin, C. Seidman, 2014, Cold Spring Harbor perspectives in medicine.

Two forms of the T-cell receptor gamma protein found on peripheral blood cytotoxic T lymphocytes.

J. Seidman, J. Mclean, M. Krangel, 1987, Nature.

Subtle Abnormalities in Contractile Function Are an Early Manifestation of Sarcomere Mutations in Dilated Cardiomyopathy

S. Colan, J. Seidman, E. Orav, 2012, Circulation. Cardiovascular genetics.

Human T cell gamma-chain gene rearrangements in acute lymphoid and nonlymphoid leukemia: comparison with the T cell receptor beta-chain gene.

J. Seidman, T. Quertermous, J. Kersey, 1986, Journal of immunology.

The PTPN11 gene is not implicated in nonsyndromic hypertrophic cardiomyopathy

J. Seidman, R. Kucherlapati, H. Rehm, 2005, American journal of medical genetics. Part A.

Increased Frequency of De Novo Copy Number Variants in Congenital Heart Disease by Integrative Analysis of Single Nucleotide Polymorphism Array and Exome Sequence Data

Yufeng Shen, Boris Yamrom, Jeremy Leipzig, 2014, Circulation research.

Genetic heterogeneity evidenced by low incidence of KAL-1 gene mutations in sporadic cases of gonadotropin-releasing hormone deficiency.

J. Seidman, W. Crowley, C. Seidman, 1997, The Journal of clinical endocrinology and metabolism.

The cloning of extracellular Ca(2+)-sensing receptors from parathyroid and kidney: molecular mechanisms of extracellular Ca(2+)-sensing.

J. Seidman, E. Brown, C. Seidman, 1995, The Journal of nutrition.

High capacity gel preparative electrophoresis for purification of fragments of genomic DNA.

J. Seidman, P. Leder, M. Edgell, 1978, Analytical biochemistry.

A novel missense mutation in the paired domain of PAX9 causes non-syndromic oligodontia

J. Seidman, R. Maas, C. Seidman, 2004, Human Genetics.

Human T-cell γ genes contain N segments and have marked junctional variability

J. Seidman, J. Strominger, T. Quertermous, 1986, Nature.

Characteristics and prognostic implications of myosin missense mutations in familial hypertrophic cardiomyopathy.

J. Seidman, H. Watkins, C. Seidman, 1992, The New England journal of medicine.

Elevated rates of force development and MgATP binding in F764L and S532P myosin mutations causing dilated cardiomyopathy.

J. Schmitt, J. Seidman, Y. Wang, 2013, Journal of molecular and cellular cardiology.

An evaluation of ribonuclease protection assays for the detection of beta-cardiac myosin heavy chain gene mutations.

J. Seidman, W. Mckenna, H. Watkins, 1994, Circulation.

Loss of FHL1 induces an age-dependent skeletal muscle myopathy associated with myofibrillar and intermyofibrillar disorganization in mice.

J. Seidman, R. Lieber, C. Seidman, 2014, Human molecular genetics.

AMP-Activated Protein Kinase in the Heart: Role During Health and Disease

J. Seidman, C. Seidman, M. Arad, 2007, Circulation research.

A human MSX1 homeodomain missense mutation causes selective tooth agenesis

J. Seidman, C. Seidman, N. Karimbux, 1996, Nature Genetics.

A complex bilateral polysyndactyly disease locus maps to chromosome 7q36

J. Seidman, C. Tabin, C. Seidman, 1994, Nature Genetics.

A nonsense mutation in MSX1 causes Witkop syndrome.

J. Seidman, U. Felbor, R. Maas, 2001, American journal of human genetics.

Haploinsufficiency of MSX1: a Mechanism for Selective Tooth Agenesis

J. Seidman, C. Seidman, Hailan Zhang, 1998, Molecular and Cellular Biology.

Brazilian urban population genetic structure reveals a high degree of admixture

J. Seidman, J. Krieger, A. Pereira, 2011, European Journal of Human Genetics.

Fulminant Myocarditis with Combination Immune Checkpoint Blockade.

J. Seidman, J. Taube, D. Roden, 2016, The New England journal of medicine.

Calcium-ion-sensing cell-surface receptors.

J. Seidman, E. Brown, C. Seidman, 1995, The New England journal of medicine.

Mutations in the human Ca2+-sensing receptor gene cause familial hypocalciuric hypercalcemia and neonatal severe hyperparathyroidism

J. Seidman, E. Brown, C. Seidman, 1993, Cell.

Rescue of cardiomyocyte dysfunction by phospholamban ablation does not prevent ventricular failure in genetic hypertrophy.

Andrew N. Carr, J. Seidman, G. Dorn, 2003, The Journal of clinical investigation.

Homozygosity mapping of the gene for alkaptonuria to chromosome 3q2

J. Seidman, C. Seidman, M. Pollak, 1993, Nature genetics.

ORE identifies extreme expression effects enriched for rare variants

F. Richter, G. E. Hoffman, K. B. Manheimer, 2019, Bioinform..

Pyogenic arthritis, pyoderma gangrenosum, and acne syndrome maps to chromosome 15q.

J. Seidman, C. Seidman, N. Lindor, 2000, American journal of human genetics.

The Bjornstad syndrome (sensorineural hearing loss and pili torti) disease gene maps to chromosome 2q34-36.

J. Seidman, R. Eavey, C. Seidman, 1998, American journal of human genetics.

The G protein alpha o subunit alters morphology, growth kinetics, and phospholipid metabolism of somatic cells

J. Seidman, E. Neer, D. Bloch, 1989 .

The G Protein αo Subunit Alters Morphology, Growth Kinetics, and Phospholipid Metabolism of Somatic Cells

J. Seidman, E. Neer, J. Bonventre, 1989, Molecular and cellular biology.

A gene for hereditary haemorrhagic telangiectasia maps to chromosome 9q3

J. Hughes, J. Seidman, C. Seidman, 1994, Nature Genetics.

Mutations in human TBX3 alter limb, apocrine and genital development in ulnar-mammary syndrome

J. Seidman, B. Bruneau, M. Bamshad, 1997, Nature Genetics.

Macrophages Facilitate Electrical Conduction in the Heart

Andrej J. Savol, P. Libby, J. Seidman, 2017, Cell.

A TBX5 dosage-sensitive gene regulatory network for human congenital heart disease

Joshua M. Stuart, J. Seidman, B. Bruneau, 2019, bioRxiv.

Cloned human and mouse kappa immunoglobulin constant and J region genes conserve homology in functional segments

J. Seidman, J. Maizel, P. Leder, 1980, Cell.

Structure of wild-type and mutant mouse β 2-microglobulin genes

J. Seidman, J. Parnes, 1982, Cell.

Structure and expression of a mouse major histocompatibility antigen gene, H-2Ld.

J. Seidman, G. Evans, D. Margulies, 1982, Proceedings of the National Academy of Sciences of the United States of America.

Control of H-2 antigen and beta 2-microglobulin gene expression in mouse trophoblast cell clones.

J. Seidman, E. Appella, K. Tanaka, 1983, Proceedings of the National Academy of Sciences of the United States of America.

Fabry Disease in Families With Hypertrophic Cardiomyopathy: Clinical Manifestations in the Classic and Later-Onset Phenotypes

Michael A. Burke, J. Seidman, B. Maron, 2017, Circulation. Cardiovascular genetics.

Clinical and Mechanistic Insights Into the Genetics of Cardiomyopathy.

Stuart A. Cook, Jonathan G. Seidman, Christine E. Seidman, 2016, Journal of the American College of Cardiology.

Autosomal dominant hypocalcaemia caused by a Ca2+-sensing receptor gene mutation

J. Seidman, E. Brown, C. Seidman, 1994, Nature Genetics.

A dynamic H3K27ac signature identifies VEGFA-stimulated endothelial enhancers and requires EP300 activity

Peter J Park, Lingyun Song, Gregory E Crawford, 2013, Genome research.

Exome-wide association study reveals novel susceptibility genes to sporadic dilated cardiomyopathy

H. Hakonarson, K. Strauch, J. Seidman, 2017, PloS one.

Titin truncating variants affect heart function in disease cohorts and the general population

Daniel Rueckert, Carlo Biffi, Antonio de Marvao, 2016, Nature Genetics.

A molecular basis for familial hypertrophic cardiomyopathy: A β cardiac myosin heavy chain gene missense mutation

J. Seidman, C. Seidman, W. McKenna, 1990, Cell.

poly(UG)-tailed RNAs in genome protection and epigenetic inheritance

M. Wickens, J. Seidman, Scott Kennedy, 2020, Nature.

poly(UG)-tailed RNAs in Genome Protection and Epigenetic Inheritance

M. Wickens, J. Seidman, Scott Kennedy, 2019, bioRxiv.

IL-11 is a crucial determinant of cardiovascular fibrosis

S. V. Heesch, J. Seidman, E. Petretto, 2017, Nature.

Structural variation across 138,134 samples in the TOPMed consortium

Mark J. P. Chaisson, Nicholette D. Palmer, M. Fornage, 2023, bioRxiv.

Single-cell meta-analysis of SARS-CoV-2 entry genes across tissues and demographics

Kyle J. Gaulton, David S. Fischer, Malte D. Luecken, 2021, Nature Medicine.

Whole Genome Sequencing Identifies CRISPLD2 as a Lung Function Gene in Children with asthma.

Ivana V. Yang, Andrew D. Johnson, Ryan D. Hernandez, 2019, Chest.

Identification of genetic loci associated with paralysis, inflammation and weight loss in mouse experimental autoimmune encephalomyelitis.

J. Seidman, H. Weiner, V. Kuchroo, 2001, International immunology.

Cardiomyocyte-enriched protein CIP protects against pathophysiological stresses and regulates cardiac homeostasis.

J. Seidman, Da-Zhi Wang, W. Pu, 2015, The Journal of clinical investigation.

Cardiac myosin binding protein C regulates postnatal myocyte cytokinesis

Gregory M. Fomovsky, Richard T. Lee, J. Seidman, 2015, Proceedings of the National Academy of Sciences.

Allele-Specific Silencing of Mutant Myh6 Transcripts in Mice Suppresses Hypertrophic Cardiomyopathy

Christine E. Seidman, J. Seidman, C. Seidman, 2013, Science.

QTL influencing autoimmune diabetes and encephalomyelitis map to a 0.15-cM region containing Il2

J. Seidman, H. Weiner, V. Kuchroo, 1999, Nature Genetics.

Murine I-A beta chain polymorphism: nucleotide sequences of three allelic I-A beta genes.

J. Seidman, R. Germain, E. Choi, 1983, Science.

Specific Class II Histocompatibility Gene Polymorphism in BB Rats

K. A. Klein, J. Seidman, A. Ben-nun, 1984, Diabetes.

De novo mutations in congenital heart disease with neurodevelopmental and other congenital anomalies

Stephan J Sanders, M. Daly, W. Chung, 2015, Science.

M. Daly, Alex Bloemendal, J. Seidman, 2017, bioRxiv.

Mutations in the genes for cardiac troponin T and alpha-tropomyosin in hypertrophic cardiomyopathy.

J. Seidman, H. Watkins, C. Seidman, 1995, The New England journal of medicine.

Genomic frontiers in congenital heart disease

J. Seidman, C. Seidman, S. Morton, 2021, Nature Reviews Cardiology.

Genomic analyses implicate noncoding de novo variants in congenital heart disease

Kathleen M. Chen, K. B. Manheimer, G. Marth, 2020, Nature Genetics.

Altered regulatory function of two familial hypertrophic cardiomyopathy troponin T mutants.

J. Seidman, C. Seidman, S. Hitchcock-DeGregori, 1999, Biochemistry.

Familial dilated cardiomyopathy caused by an alpha-tropomyosin mutation: the distinctive natural history of sarcomeric dilated cardiomyopathy.

Birgit Funke, Christine E Seidman, S. Colan, 2010, Journal of the American College of Cardiology.

Cells and gene expression programs in the adult human heart

Matthias Heinig, Daniel Reichart, Sarah A. Teichmann, 2020, bioRxiv.

Contribution of rare transmitted and de novo variants among 2 , 871 1 congenital heart disease probands

Deepak, Stephan J Sanders, W. Chung, 2017 .

Epigenetic repression of cardiac progenitor gene expression by Ezh2 is required for postnatal cardiac homeostasis

J. Seidman, B. Bruneau, A. Tarakhovsky, 2011, Nature Genetics.

De Novo Damaging Variants, Clinical Phenotypes, and Post-Operative Outcomes in Congenital Heart Disease

Michael F Swartz, K. B. Manheimer, W. Chung, 2020, Circulation. Genomic and precision medicine.

Global impact of somatic structural variation on the DNA methylome of human cancers

Lovelace J. Luquette, L. Chin, P. Park, 2019, Genome Biology.

Spatiotemporal Multi-Omics Mapping Generates a Molecular Atlas of the Aortic Valve and Reveals Networks Driving Disease

Joshua D. Hutcheson, J. Seidman, Amitabh Sharma, 2018, Circulation.

Modeling Human TBX5 Haploinsufficiency Predicts Regulatory Networks for Congenital Heart Disease.

Joshua M. Stuart, J. Seidman, B. Bruneau, 2019, Developmental cell.

Mutations in human TBX5 [corrected] cause limb and cardiac malformation in Holt-Oram syndrome.

J. Seidman, R. Kucherlapati, C. Seidman, 1997, Nature genetics.

A comparison of two cloned mouse β-globin genes and their surrounding and intervening sequences

J. Seidman, P. Leder, M. Edgell, 1978, Cell.

Tbx5 is required for forelimb bud formation and continued outgrowth

J. Seidman, C. Tabin, B. Bruneau, 2003, Development.

Evolution Evolutionary analyses of hedgehog and Hoxd-10 genes in fish species closely related to the zebrafish

J. Seidman, A. McMahon, 1996 .

Mutations in the cardiac myosin binding protein–C gene on chromosome 11 cause familial hypertrophic cardiomyopathy

J. Seidman, B. Maron, H. Watkins, 1995, Nature Genetics.

Cardiac myosin binding protein-C is essential for thick-filament stability and flexural rigidity.

J. Seidman, C. Seidman, J. Vigoreaux, 2009, Biophysical journal.

The Genetic Basis for Cardiomyopathy from Mutation Identification to Mechanistic Paradigms

J. Seidman, C. Seidman, Christine Seidman, 2001, Cell.

The arrangement and rearrangement of antibody genes

J. Seidman, P. Leder, Jonathan G. Seidman, 1978, Nature.

Production of homozygous mutant ES cells with a single targeting construct

J. Seidman, R. Mortensen, D. Conner, 1992, Molecular and cellular biology.

Functional insertion of an Alu type 2 (B2 SINE) repetitive sequence in murine class I genes.

J. Seidman, G. Khoury, G. Jay, 1984, Science.

Genome sequencing as a first-line genetic test in familial dilated cardiomyopathy

J. Seidman, D. Fatkin, M. Cowley, 2018, Genetics in Medicine.

Whole-Genome Sequencing as a First-Line Genetic Test in Familial Dilated Cardiomyopathy

J. Seidman, D. Fatkin, M. Cowley, 2018, Genetics in Medicine.

Human γ-chain genes are rearranged in leukaemic T cells and map to the short arm of chromosome 7

T. Waldmann, J. Seidman, T. Shows, 1985, Nature.

Filter-based hybridization capture of subgenomes enables resequencing and copy-number detection

J. Seidman, H. Rehm, R. Kucherlapati, 2009, Nature Methods.

Systemic lupus erythematosus is not genetically linked to the beta chain of the T cell receptor.

K. A. Klein, J. Seidman, P. Schur, 1986, Arthritis and rheumatism.

Isolation of Nuclei from Mammalian Cells and Tissues for Single‐Nucleus Molecular Profiling

J. Seidman, N. Hübner, C. Seidman, 2021, Current protocols.

5'RNA-Seq identifies Fhl1 as a genetic modifier in cardiomyopathy.

J. Seidman, M. Bulyk, P. D. De Jager, 2014, The Journal of clinical investigation.

Activation of multiple signaling pathways causes developmental defects in mice with a Noonan syndrome–associated Sos1 mutation.

J. Seidman, R. Kucherlapati, B. Neel, 2010, The Journal of clinical investigation.

Familial dilated cardiomyopathy locus maps to chromosome 2q31.

J A Osborne, H Niimura, S. Solomon, 1999, Circulation.

Loss of epigenetic information as a cause of mammalian aging

Andreas R. Pfenning, Brendan L. O’Connell, Margarita V. Meer, 2023, Cell.

Direct Reprogramming of Non-limb Fibroblasts to Cells with Properties of Limb Progenitors

J. Seidman, C. Tabin, O. Pourquié, 2021, bioRxiv.

Transcription factor haploinsufficiency: when half a loaf is not enough.

J. Seidman, C. Seidman, J G Seidman, 2002, The Journal of clinical investigation.

Progression to diabetes in nonobese diabetic (NOD) mice with transgenic T cell receptors.

J. Seidman, G. Eisenbarth, A. Rosenzweig, 1993, Science.

A locus for inherited focal segmental glomerulosclerosis maps to chromosome 19q13.

J. Seidman, C. Seidman, M. Haas, 1998, Kidney international.

Efficient in vivo genome editing prevents hypertrophic cardiomyopathy in mice

Gregory A. Newby, J. Seidman, H. Wakimoto, 2023, Nature Medicine.

Contribution of Noncanonical Splice Variants to TTN Truncating Variant Cardiomyopathy

Parth N. Patel, J. Seidman, S. Cook, 2021, Circulation. Genomic and precision medicine.

Discordant clinical features of identical hypertrophic cardiomyopathy twins

J. Seidman, A. Pereira, C. Seidman, 2021, Proceedings of the National Academy of Sciences.

Discovery and analyses of pathogenic variants in explanted hearts from primary cardiomyopathy patients

J. Seidman, C. Seidman, J. Gorham, 2020 .

Precision Medicine in the Management of Dilated Cardiomyopathy: JACC State-of-the-Art Review.

J. Seidman, D. Fatkin, C. Seidman, 2019, Journal of the American College of Cardiology.

Genetic Variants Associated With Cancer Therapy–Induced Cardiomyopathy

Parth N. Patel, J. Seidman, D. O’Regan, 2019, Circulation.

Hypertrophic cardiomyopathy mutations in MYBPC3 dysregulate myosin

Christine E Seidman, Sakthivel Sadayappan, J. Seidman, 2019, Science Translational Medicine.

Abstract 571: MYBPC3 Mutations Cause Hypertrophic Cardiomyopathy by Dysregulating Myosin: Implications for Therapy

J. Seidman, H. Watkins, C. Seidman, 2018, Circulation Research.

A gene-centric strategy for identifying disease-causing rare variants in dilated cardiomyopathy

Jacob T. Munro, Angharad M Roberts, J. Seidman, 2018, Genetics in Medicine.

Effects of myosin variants on interacting-heads motif explain distinct hypertrophic and dilated cardiomyopathy phenotypes

J. Seidman, J. Ware, C. Seidman, 2017, eLife.

The genetic basis for cardiac remodeling.

Christine E Seidman, Ferhaan Ahmad, J. Seidman, 2005, Annual review of genomics and human genetics.

Expression and functional assessment of a truncated cardiac troponin T that causes hypertrophic cardiomyopathy. Evidence for a dominant negative action.

J. Seidman, H. Watkins, C. Seidman, 1996, The Journal of clinical investigation.

Clinical features of hypertrophic cardiomyopathy caused by mutation of a "hot spot" in the alpha-tropomyosin gene.

J. Seidman, B. Maron, H. Watkins, 1997, Journal of the American College of Cardiology.

A small-molecule inhibitor of sarcomere contractility suppresses hypertrophic cardiomyopathy in mice

Christine E. Seidman, James A. Spudich, Robert S. McDowell, 2016, Science.

Dissection of Chromosome 18 Blood Pressure and Salt-Sensitivity Quantitative Trait Loci in the Spontaneously Hypertensive Rat

Nathan R. Qi, J. Seidman, T. Kurtz, 2009, Hypertension.

GATA6 mutations in hiPSCs inform mechanisms for maldevelopment of the heart, pancreas, and diaphragm

W. Chung, J. Seidman, D. Srivastava, 2020, eLife.

A novel custom resequencing array for dilated cardiomyopathy

J. Seidman, H. Rehm, C. Seidman, 2010, Genetics in Medicine.

A κ-immunoglobulin gene is formed by site-specific recombination without further somatic mutation

J. Seidman, P. Leder, E. E. Max, 1979, Nature.

Sequences of five potential recombination sites encoded close to an immunoglobulin kappa constant region gene.

J. Seidman, P. Leder, E. E. Max, 1979, Proceedings of the National Academy of Sciences of the United States of America.

Cardiac fibrosis in mice with hypertrophic cardiomyopathy is mediated by non-myocyte proliferation and requires Tgf-β.

Roger R Markwald, Christine E Seidman, J. Schmitt, 2010, The Journal of clinical investigation.

Single-molecule mechanics of R403Q cardiac myosin isolated from the mouse model of familial hypertrophic cardiomyopathy.

J. Seidman, C. Seidman, M. Tyska, 2000, Circulation research.

A Mouse Model of Familial Hypertrophic Cardiomyopathy

Frederick J. Schoen, Christine E. Seidman, David A. Conner, 1996, Science.

Preparation of rAAV9 to Overexpress or Knockdown Genes in Mouse Hearts.

J. Seidman, Da-Zhi Wang, W. Pu, 2016, Journal of visualized experiments : JoVE.

Eucaryotic chromosome transfer: production of a murine-specific cosmid library from a neor-linked fragment of murine chromosome 17

J. Seidman, D. Housman, D. Nelson, 1986, Molecular and cellular biology.

Nationwide Study on Hypertrophic Cardiomyopathy in Iceland: Evidence of a MYBPC3 Founder Mutation

Michael A. Burke, D. Gudbjartsson, K. Stefánsson, 2014, Circulation.

Dissection of serological and cytolytic T lymphocyte epitopes on murine major histocompatibility antigens by a recombinant H-2 gene separating the first two external domains

J. Seidman, C. Murre, K. Ozato, 1984, The Journal of experimental medicine.

Construction, expression and recognition of an H—2 molecule lacking its carboxyl terminus

J. Seidman, S. Burakoff, C. Bernabéu, 1984, Nature.

AAV9 Delivery of shRNA to the Mouse Heart

J. Seidman, H. Wakimoto, Jianming Jiang, 2016, Current protocols in molecular biology.

A Pan-Cancer Compendium of Genes Deregulated by Somatic Genomic Rearrangement across More Than 1,400 Cases.

Lovelace J. Luquette, L. Chin, P. Park, 2018, Cell reports.

Two kappa immunoglobulin genes are expressed in the myeloma S107

J. Seidman, P. Leder, E. E. Max, 1981, Cell.

Detection of a frequent restriction fragment length polymorphism in the human T cell antigen receptor beta chain locus. A potential diagnostic tool.

J. Seidman, P. Leder, C. Morton, 1985, The Journal of clinical investigation.

Eukaryotic chromosome transfer: linkage of the murine major histocompatibility complex to an inserted dominant selectable marker.

J. Seidman, D. Housman, D. Nelson, 1984, Proceedings of the National Academy of Sciences of the United States of America.

Heavy and light chain contributions to antigen binding in an anti-digoxin chain recombinant antibody produced by transfection of cloned anti-digoxin antibody genes.

J. Seidman, E. Haber, M. N. Margolies, 1990, Molecular immunology.

Immunoglobulin γ1 heavy chain gene: Structural gene sequences cloned in a bacterial plasmid

J. Seidman, P. Leder, T. Honjo, 1980 .

Immunoglobulin V/J recombination is accompanied by deletion of joining site and variable region segments.

S P Kwan, J. Seidman, P. Leder, 1980, Proceedings of the National Academy of Sciences of the United States of America.

Dissection of serological and cytolytic T lymphocyte epitopes on murine major histocompatibility antigens by a recombinant H-2 gene separating the first two external domains

J. Seidman, C. Murre, K. Ozato, 1984, The Journal of experimental medicine.

Exon shuffling: mapping polymorphic determinants on hybrid mouse transplantation antigens

J. Seidman, G. Evans, D. Margulies, 1982, Nature.

J. Seidman, P. Leder, M. Edgell, 1978, Proceedings of the National Academy of Sciences of the United States of America.

Chapter 5 Construction of Recombinant Dna Libraries Construction of Recombinant Dna Libraries Construction of Recombinant Dna Libraries Overview of Recombinant Dna Libraries Genomic Dna Libraries Representation and Randomness Construction of Recombinant Dna Libraries Subgenomic Dna Libraries Vectors

J. Seidman, 2022 .

Genetic causes of human heart failure.

Jonathan Seidman, Hiroyuki Morita, Christine E Seidman, 2005, The Journal of clinical investigation.

Characterization of a regulatory region of the steroid 21-hydroxylase gene.

J. Seidman, D. Chaplin, B. Schimmer, 1986, The Journal of biological chemistry.

Identifying sarcomere gene mutations in hypertrophic cardiomyopathy: a personal history.

J. Seidman, C. Seidman, 2011, Circulation research.

Glycogen storage diseases presenting as hypertrophic cardiomyopathy.

J. Seidman, J. Saul, B. Maron, 2005, The New England journal of medicine.

Phenotypic diversity in hypertrophic cardiomyopathy.

Christine E Seidman, J. Seidman, C. Seidman, 2002, Human molecular genetics.

Tbx5-dependent rheostatic control of cardiac gene expression and morphogenesis.

Kazuko Koshiba-Takeuchi, R Mark Henkelman, Christine E Seidman, 2006, Developmental biology.

H‐2 hemizygous mutants from a heterozygous cell line: role of mitotic recombination.

J. Seidman, G. Evans, D. Margulies, 1983, The EMBO journal.

Ca2+ dysregulation in Ryr1I4895T/wt mice causes congenital myopathy with progressive formation of minicores, cores, and nemaline rods

J. Seidman, C. Seidman, D. Maclennan, 2009, Proceedings of the National Academy of Sciences.

An Ryr1I4895T mutation abolishes Ca2+ release channel function and delays development in homozygous offspring of a mutant mouse line

J. Seidman, A. Gramolini, C. Seidman, 2007, Proceedings of the National Academy of Sciences.

A mutant immunoglobulin light chain is formed by aberrant DNA- and RNA-splicing events

J. Seidman, P. Leder, Jonathan G. Seidman, 1980, Nature.

Transcription factor protein interactomes reveal genetic determinants in heart disease

Mauro W. Costa, K. Pollard, N. Krogan, 2022, Cell.

Abnormal recombination products result from aberrant DNA rearrangement of the human T-cell antigen receptor beta-chain gene.

J. Seidman, A. Duby, 1986, Proceedings of the National Academy of Sciences of the United States of America.

Severe Heart Failure and Early Mortality in a Double-Mutation Mouse Model of Familial Hypertrophic Cardiomyopathy

J. Seidman, C. Seidman, M. Bogoyevitch, 2008, Circulation.

Sarcomere Protein Gene Mutations in Hypertrophic Cardiomyopathy of the Elderly

J. Seidman, B. Maron, C. Seidman, 2002, Circulation.

Genome-wide association study identifies a susceptibility locus for thoracic aortic aneurysms and aortic dissections spanning FBN1 at 15q21.1

S. Leal, J. Seidman, J. Belmont, 2011, Nature Genetics.

A T-cell receptor γ/CD3 complex found on cloned functional lymphocytes

J. Seidman, J. Borst, S. Ang, 1987, Nature.

Allele-specific expression in the human heart and its application to postoperative atrial fibrillation and myocardial ischemia

J. Seidman, G. Couper, S. Aranki, 2016, Genome Medicine.

Deficient Cation Channel Regulation in Neurons From Mice With Targeted Disruption of the Extracellular Ca2+-Sensing Receptor Gene

J. Seidman, E. Brown, C. Seidman, 1997, Brain Research Bulletin.

HOXA2 Haploinsufficiency in Dominant Bilateral Microtia and Hearing Loss

J. Seidman, R. Eavey, Kerry K. Brown, 2013, Human mutation.

Heterozygosity for a loss-of-function mutation in GALNT2 improves plasma triglyceride clearance in man.

A. Zwinderman, J. Seidman, L. Tabak, 2011, Cell metabolism.

Reduced penetrance, variable expressivity, and genetic heterogeneity of familial atrial septal defects.

J. Seidman, D. Fatkin, C. Seidman, 1998, Circulation.

The gene responsible for familial hypocalciuric hypercalcemia maps to chromosome 3q in four unrelated families

J. Seidman, E. Brown, C. Seidman, 1992, Nature Genetics.

Hereditary postlingual sensorineural hearing loss mapping to chromosome Xq21.

J. Seidman, R. Eavey, H. Watkins, 1999, The American journal of otology.

Robust identification of mosaic variants in congenital heart disease

K. B. Manheimer, W. Chung, J. Seidman, 2018, Human Genetics.

Flagellar and acrosomal abnormalities associated with testicular HSV-tk expression in the mouse.

J. Seidman, J. Pudney, K. Huttner, 1993, Biology of reproduction.

Gamma-delta T cells in Chediak-Higashi syndrome.

J. Seidman, R. Holcombe, S. Ang, 1990, Acta haematologica.

The clinical and genetic spectrum of the Holt-Oram syndrome (heart-hand syndrome)

S. Solomon, J. Seidman, A. Poznanski, 1994, The New England journal of medicine.

Merits and pitfalls of genetic testing in a hypertrophic cardiomyopathy clinic.

J. Seidman, E. Arbustini, D. Freimark, 2014, The Israel Medical Association journal : IMAJ.

Development of left ventricular hypertrophy in adults in hypertrophic cardiomyopathy caused by cardiac myosin-binding protein C gene mutations.

H Niimura, J. Seidman, B. Maron, 2001, Journal of the American College of Cardiology.

Lamin A/C haploinsufficiency causes dilated cardiomyopathy and apoptosis-triggered cardiac conduction system disease.

Ferhaan Ahmad, J. Seidman, G. Fishman, 2008, Journal of molecular and cellular cardiology.

Stable Gene Targeting in Human Cells Using Single-Strand Oligonucleotides with Modified Bases

Adrian W. Briggs, G. Church, J. Seidman, 2012, PloS one.

CLCN5 mutation Ser244Leu is associated with X-linked renal failure without X-linked recessive hypophosphatemic rickets.

J. Seidman, C. Seidman, V. Buckalew, 1998, Kidney international.

An element regulating adrenal-specific steroid 21-hydroxylase expression is located within the slp gene.

J. Seidman, M. Szyf, K. Parker, 1992, The Journal of biological chemistry.

Cytotoxic T lymphocyte recognition of class I H-2 antigens after DNA-mediated gene transfer.

J. Seidman, G. Evans, D. Margulies, 1984, Federation proceedings.

Mechanisms of Congenital Heart Disease Caused by NAA15 Haploinsufficiency

Craig C. Benson, W. Chung, J. Seidman, 2021, Circulation research.

Locus for Familial Migrainous Vertigo Disease Maps to Chromosome 5q35

J. Seidman, S. Merchant, C. Seidman, 2009, The Annals of otology, rhinology, and laryngology.

Familial hypertrophic cardiomyopathy and atrial fibrillation caused by Arg663His beta-cardiac myosin heavy chain mutation.

J. Seidman, B. Maron, D. Fatkin, 1999, The American journal of cardiology.

Complex genomic rearrangement in CCS‐LacZ transgenic mice

J. Seidman, G. Fishman, S. Rentschler, 2007, Genesis.

Cloning and functional characterization of extracellular Ca(2+)-sensing receptors from parathyroid and kidney.

J. Seidman, E. Brown, C. Seidman, 1995, Bone.

Activin type II receptor signaling in cardiac aging and heart failure

Vassilios J. Bezzerides, N. Houstis, J. Seidman, 2019, Science Translational Medicine.

The L-type calcium channel inhibitor diltiazem prevents cardiomyopathy in a mouse model.

J. Schmitt, D. Kass, J. Seidman, 2002, The Journal of clinical investigation.

Variation in the 4q25 Chromosomal Locus Predicts Atrial Fibrillation After Coronary Artery Bypass Graft Surgery

J. Seidman, P. Ellinor, S. Aranki, 2009, Circulation. Cardiovascular genetics.

Preclinical diagnosis of familial hypertrophic cardiomyopathy by genetic analysis of blood lymphocytes.

J. Seidman, H. Watkins, C. Seidman, 1991, The New England journal of medicine.

β-Arrestin1 Knockout Mice Appear Normal but Demonstrate Altered Cardiac Responses to β-Adrenergic Stimulation

J. Seidman, S. Vatner, C. Seidman, 1997 .

Novel and Annotated Long Noncoding RNAs Associated with Ischemia in the Human Heart

J. Seidman, V. Cameron, S. Aranki, 2021, International journal of molecular sciences.

Hereditary inclusion body myopathy maps to chromosome 9p1-q1.

J. Seidman, C. Seidman, S. Mitrani‐Rosenbaum, 1996, Human molecular genetics.

Transgenic Mice Overexpressing Mutant PRKAG2 Define the Cause of Wolff-Parkinson-White Syndrome in Glycogen Storage Cardiomyopathy

Ferhaan Ahmad, J. Schmitt, J. Seidman, 2003, Circulation.

The Muscle-Bound Heart.

J. Seidman, C. Seidman, A. Fahed, 2016, Cardiac electrophysiology clinics.

Neonatal cardiomyopathy in mice homozygous for the Arg403Gln mutation in the alpha cardiac myosin heavy chain gene.

F J Schoen, J. Seidman, D. Turnbull, 1999, The Journal of clinical investigation.

Force Generation via β-Cardiac Myosin, Titin, and α-Actinin Drives Cardiac Sarcomere Assembly from Cell-Matrix Adhesions.

Anant Chopra, William J Polacheck, Matthew L. Kutys, 2018, Developmental cell.

Titin mutations in iPS cells define sarcomere insufficiency as a cause of dilated cardiomyopathy

George Church, Wolfgang A. Linke, Stuart A. Cook, 2015, Science.

Familial hypertrophic cardiomyopathy: a genetic model of cardiac hypertrophy.

J. Seidman, H. Watkins, C. Seidman, 1995, Human molecular genetics.

Loss of RNA expression and allele-specific expression associated with congenital heart disease

Yufeng Shen, Andrew J Sharp, Nihir Patel, 2016, Nature Communications.

SarcTrack

Jyoti Rao, Arun Sharma, Marcelo Cicconet, 2019, Circulation research.

The spectrum of mutations in TBX3: Genotype/Phenotype relationship in ulnar-mammary syndrome.

J. Seidman, M. Bamshad, L. Jorde, 1999, American journal of human genetics.

Characterization of endoglin and identification of novel mutations in hereditary hemorrhagic telangiectasia.

J. Hughes, J. Seidman, C. Seidman, 1997, American journal of human genetics.

Sporadic hypertrophic cardiomyopathy due to de novo myosin mutations.

J. Seidman, W. Mckenna, H. Watkins, 1992, The Journal of clinical investigation.

The products of transferred H-2 genes express determinants that restrict hapten-specific cytotoxic T cells.

J. Seidman, G. Evans, D. Margulies, 1983, Journal of immunology.

Nucleotide sequence of mutant I-Aβbm12 gene is evidence for genetic exchange between mouse immune response genes

J. Seidman, K. McIntyre, 1984, Nature.

Aberrant activation of AMP-activated protein kinase remodels metabolic network in favor of cardiac glycogen storage.

J. Seidman, J. Balschi, C. Seidman, 2007, The Journal of clinical investigation.

Identifying Candidate Genes

J. Seidman, C. Seidman, 2012 .

Characterization of a Q subregion gene in the murine major histocompatibility complex.

J. Seidman, E. Rinchik, M. Lynes, 1985, Proceedings of the National Academy of Sciences of the United States of America.

Embryonic stem cells lacking a functional inhibitory G-protein subunit (alpha i2) produced by gene targeting of both alleles.

J. Seidman, E. Neer, R. Mortensen, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Whole Genome De Novo Variant Identification with FreeBayes and Neural Network Approaches

Yufeng Shen, Nihir Patel, Felix Richter, 2020, bioRxiv.

Gene Mutations in Apical Hypertrophic Cardiomyopathy

J. Seidman, B. Maron, C. Seidman, 2005, Circulation.

Homozygous Mutation in Cardiac Troponin T: Implications for Hypertrophic Cardiomyopathy

J. Seidman, C. Seidman, C. Farver, 2000, Circulation.

Assessing the phenotypic effects in the general population of rare variants in genes for a dominant Mendelian form of diabetes

Stefan Johansson, Jason Flannick, Christopher J O'Donnell, 2013, Nature Genetics.

THE ARRANGEMENT, REARRANGEMENT AND ORIGIN OF IMMUNOGLOBULIN GENES

J. Seidman, P. Leder, E. E. Max, 1979 .

Origin of immunoglobulin gene diversity: the evidence and a restriction-modification model.

J. Seidman, P. Leder, T. Honjo, 1977, Cold Spring Harbor symposia on quantitative biology.

IEWPOINT roposal for Contemporary Screening Strategies n Families With Hypertrophic Cardiomyopathy

J. Seidman, C. Seidman, J. Maron, 2004 .

Assessment of Diastolic Function With Doppler Tissue Imaging to Predict Genotype in Preclinical Hypertrophic Cardiomyopathy

S. Solomon, J. Seidman, B. Maron, 2002, Circulation.

Independent origin of identical beta cardiac myosin heavy-chain mutations in hypertrophic cardiomyopathy.

J. Seidman, W. Mckenna, H. Watkins, 1993, American journal of human genetics.

A disease locus for familial hypertrophic cardiomyopathy maps to chromosome 1q3

J. Seidman, H. Watkins, C. Seidman, 1993, Nature Genetics.

Familial hypertrophic cardiomyopathy is a genetically heterogeneous disease.

S. Solomon, J. Seidman, C. Seidman, 1990, The Journal of clinical investigation.

Mapping a gene for familial hypertrophic cardiomyopathy to chromosome 14q1.

S. Solomon, J. Seidman, R. Holcombe, 1989, The New England journal of medicine.

Molecular profiling of dilated cardiomyopathy that progresses to heart failure.

Michael A. Burke, J. Seidman, C. Seidman, 2016, JCI insight.

Alpha blockade potentiates CPVT therapy in calsequestrin-mutant mice.

J. Seidman, C. Seidman, M. Eldar, 2013, Heart rhythm.

Identification of functional regions on the I-Ab molecule by site-directed mutagenesis.

J. Seidman, L. Glimcher, J. Smith, 1986, Proceedings of the National Academy of Sciences of the United States of America.

Preface

J. Haines, J. Seidman, Douglas R. Smith, 2011 .

Sarcomere Gene Mutations in Hypertrophy and Heart Failure

J. Seidman, C. Seidman, R. Nagai, 2010, Journal of cardiovascular translational research.

Missense mutations in the BCS1L gene as a cause of the Björnstad syndrome.

J. Seidman, R. Eavey, C. Seidman, 2007, The New England journal of medicine.

Linkage of beta 2-microglobulin and ly-m11 by molecular cloning and DNA-mediated gene transfer.

J. Seidman, D. Margulies, J. Parnes, 1983, Proceedings of the National Academy of Sciences of the United States of America.

Loss-of-Function Mutations in PTPN11 Cause Metachondromatosis, but Not Ollier Disease or Maffucci Syndrome

J. Seidman, M. Vikkula, I. Holm, 2011, PLoS genetics.

Sex differences in gene expression in response to ischemia in the human myocardium

J. Seidman, B. Stranger, S. Aranki, 2018, bioRxiv.

Exclusion of Atypical Vitelliform Macular Dystrophy from 8 q 24 . 3 and from Other Known Macular Degenerative Loci

J. Seidman, L. Donoso, C. Seidman, 2006 .

Filamin C Cardiomyopathy Variants Cause Protein and Lysosome Accumulation

Jourdan K. Ewoldt, S. Gygi, J. Seidman, 2021, Circulation research.

Electrophysiologic characterization and postnatal development of ventricular pre-excitation in a mouse model of cardiac hypertrophy and Wolff-Parkinson-White syndrome.

J. Seidman, C. Seidman, C. Berul, 2003, Journal of the American College of Cardiology.

Human T-cell gamma chain genes: organization, diversity, and rearrangement.

J. Seidman, J. Strominger, T. Quertermous, 1986, Science.

Cardiomyocyte infection by Trypanosoma cruzi promotes innate immune response and glycolysis activation

J. Seidman, J. Krieger, C. Seidman, 2023, Frontiers in Cellular and Infection Microbiology.

Reversibility of PRKAG2 Glycogen-Storage Cardiomyopathy and Electrophysiological Manifestations

Ferhaan Ahmad, J. Seidman, C. Seidman, 2008, Circulation.

mTOR signaling inhibition decreases lysosome migration and impairs the success of Trypanosoma cruzi infection and replication in cardiomyocytes.

J. Seidman, J. Krieger, C. Seidman, 2023, Acta tropica.

Human gamma-chain genes are rearranged in leukaemic T cells and map to the short arm of chromosome 7.

T. Waldmann, J. Seidman, T. Shows, 1985, Nature.

A Broad Phenotypic Screen Identifies Novel Phenotypes Driven by a Single Mutant Allele in Huntington’s Disease CAG Knock-In Mice

Edith T. Lopez, H. Fuchs, T. Gillis, 2013, PloS one.

Genome-Wide Assessment for Genetic Variants Associated with Ventricular Dysfunction after Primary Coronary Artery Bypass Graft Surgery

Dan M. Roden, Christine E. Seidman, Kuang-Yu Liu, 2011, PloS one.

Association of Damaging Variants in Genes With Increased Cancer Risk Among Patients With Congenital Heart Disease

W. Chung, J. Seidman, Yufeng Shen, 2020, JAMA cardiology.

Genetic and Phenotypic Landscape of Peripartum Cardiomyopathy

J. Seidman, D. Judge, S. Goland, 2021, Circulation.

Cardiovascular homeostasis dependence on MICU2, a regulatory subunit of the mitochondrial calcium uniporter

V. Mootha, J. Seidman, C. Seidman, 2017, Proceedings of the National Academy of Sciences.

Altered crossbridge kinetics in the alphaMHC403/+ mouse model of familial hypertrophic cardiomyopathy.

J. Seidman, C. Seidman, D. Maughan, 1999, Circulation research.

Altered Crossbridge Kinetics in the a MHC 403 / 1 Mouse Model of Familial Hypertrophic Cardiomyopathy

J. Seidman, C. Seidman, D. Maughan, 1999 .

Comparison of Two Murine Models of Familial Hypertrophic Cardiomyopathy

F J Schoen, James O. Mudd, D. Kass, 2001, Circulation research.

Mutations in cardiac myosin heavy chain genes cause familial hypertrophic cardiomyopathy.

J. Seidman, C. Seidman, J. G. Seidman, 1991, Molecular biology & medicine.

Construction of normalized RNA-seq libraries for next-generation sequencing using the crab duplex-specific nuclease.

J. Seidman, J. Gorham, Danos C. Christodoulou, 2011, Current protocols in molecular biology.

Nucleotide sequence of an arginine transfer ribonucleic acid from bacteriophage T4.

J. Seidman, W. McClain, G. Mazzara, 1977, The Journal of biological chemistry.

Increased Burden of Cardiovascular Disease in Carriers of APOL1 Genetic Variants

S. Gabriel, D. Altshuler, J. Hirschhorn, 2014, Circulation research.

Genetics of cancer therapy-associated cardiotoxicity.

J. Seidman, C. Seidman, Yuri Kim, 2022, Journal of molecular and cellular cardiology.

Ouabain induces secretion of proatrial natriuretic factor by rat atrial cardiocytes.

J. Seidman, C. Seidman, K. Bloch, 1988, American Journal of Physiology.

Plakophilin-2 truncating variants impair cardiac contractility by disrupting sarcomere stability and organization

Jourdan K. Ewoldt, J. Seidman, C. Seidman, 2021, Science advances.

Integrative Analysis of PRKAG2 Cardiomyopathy iPS and Microtissue Models Identifies AMPK as a Regulator of Metabolism, Survival, and Fibrosis.

Michael A. Burke, J. Seidman, R. Gerszten, 2017, Cell reports.

Integrative Analysis of PRKAG2 Cardiomyopathy iPS and Microtissue Models Identifies AMPK as a Regulator of Metabolism, Survival, and Fibrosis.

Michael A. Burke, J. Seidman, R. Gerszten, 2016, Cell reports.

Myocardial fibrosis as an early manifestation of hypertrophic cardiomyopathy.

S. Colan, J. Seidman, R. Kwong, 2010, The New England journal of medicine.

Cell cycle defects underlie childhood-onset cardiomyopathy associated with Noonan syndrome

J. Seidman, T. Schwarzmayr, C. Seidman, 2021, iScience.

Somatic events modify hypertrophic cardiomyopathy pathology and link hypertrophy to arrhythmia.

Christopher Semsarian, Christine E Seidman, J. Seidman, 2005, Proceedings of the National Academy of Sciences of the United States of America.

A dynamic H 3 K 27 ac signature identifies VEGFA-stimulated endothelial enhancers and requires EP 300 activity Citation

Daniel S. Day, P. Park, J. Seidman, 2013 .

Phenotype and prognostic correlations of the converter region mutations affecting the β myosin heavy chain

J. Seidman, A. Mazzanti, D. Freimark, 2015, Heart.

The role of mutant protein level in autosomal recessive catecholamine dependent polymorphic ventricular tachycardia (CPVT2).

J. Seidman, C. Seidman, M. Eldar, 2013, Biochemical pharmacology.

Optimizing catecholaminergic polymorphic ventricular tachycardia therapy in calsequestrin-mutant mice.

J. Seidman, C. Seidman, M. Eldar, 2010, Heart rhythm.

Calsequestrin 2 (CASQ2) mutations increase expression of calreticulin and ryanodine receptors, causing catecholaminergic polymorphic ventricular tachycardia.

J. Seidman, C. Seidman, C. Berul, 2007, The Journal of clinical investigation.

Genetic profiling of fatty acid desaturase polymorphisms identifies patients who may benefit from high-dose omega-3 fatty acids in cardiac remodeling after acute myocardial infarction—Post-hoc analysis from the OMEGA-REMODEL randomized controlled trial

E. Antman, J. Seidman, R. Kwong, 2019, PloS one.

The L-type calcium channel inhibitor diltiazem prevents cardiomyopathy in a mouse model

J. Schmitt, D. Kass, J. Seidman, 2002 .

Narrative Review: Harnessing Molecular Genetics for the Diagnosis and Management of Hypertrophic Cardiomyopathy

J. Seidman, C. Seidman, Libin Wang, 2010, Annals of Internal Medicine.

Novel Locus for an Inherited Cardiomyopathy Maps to Chromosome 7

Barry J Maron, Christine E Seidman, J. Seidman, 2006, Circulation.

Calcium Signaling Pathway Genes RUNX2 and CACNA1C Are Associated With Calcific Aortic Valve Disease

Y. Bossé, J. Seidman, J. Tardif, 2015, Circulation. Cardiovascular genetics.

Association of Variants in BAG3 With Cardiomyopathy Outcomes in African American Individuals

Anne L. Taylor, J. Seidman, C. Yancy, 2018, JAMA cardiology.

Targeted and genome-wide sequencing reveal single nucleotide variations impacting specificity of Cas9 in human stem cells

Gang Wang, George Church, Jonathan Seidman, 2014, Nature Communications.

DNA Break-Induced Epigenetic Drift as a Cause of Mammalian Aging

J. Seidman, S. Bonasera, K. Tsubota, 2019, bioRxiv.

A gene defect that causes conduction system disease and dilated cardiomyopathy maps to chromosome 1p1–1q1

A. Kong, J. Seidman, M. Fishman, 1994, Nature Genetics.

N488I Mutation of the γ2-Subunit Results in Bidirectional Changes in AMP-Activated Protein Kinase Activity

J. Seidman, C. Seidman, J. Ingwall, 2005 .

Complex regulation of class II gene expression: analysis with class II mutant cell lines.

J. Seidman, L. Glimcher, D. McKean, 1985, Journal of immunology.

Diastolic dysfunction and altered energetics in the alphaMHC403/+ mouse model of familial hypertrophic cardiomyopathy.

J. Seidman, C. Seidman, J. Ingwall, 1998, The Journal of clinical investigation.

proteins during development of heart failure Exercise training normalizes altered calcium-handling

J. Seidman, C. Seidman, M. Eldar, 2015 .

Shared Genetic Predisposition in Peripartum and Dilated Cardiomyopathies.

J. Seidman, S. Cook, J. Ware, 2016, The New England journal of medicine.

Joint analysis of left ventricular expression and circulating plasma levels of Omentin after myocardial ischemia

J. Seidman, S. Aranki, S. Body, 2017, Cardiovascular Diabetology.

A Tension-Based Model Distinguishes Hypertrophic versus Dilated Cardiomyopathy

J. Seidman, S. Houser, M. Regnier, 2016, Cell.

Cardiac myosin missense mutations cause dilated cardiomyopathy in mouse models and depress molecular motor function

Ferhaan Ahmad, J. Schmitt, J. Seidman, 2006, Proceedings of the National Academy of Sciences.

Robust identification of mosaic variants in congenital heart disease

K. B. Manheimer, J. Seidman, Yufeng Shen, 2018, Human Genetics.

Five steps in the conversion of a large precursor RNA into bacteriophage proline and serine transfer RNAs.

B. Barrell, J. Seidman, W. McClain, 1975, Journal of molecular biology.

Clinical and genetic linkage analysis of a large Venezuelan kindred with Usher syndrome.

J. Seidman, R. Eavey, I. Keogh, 2004, International journal of pediatric otorhinolaryngology.

Cardiac-Specific YAP Activation Improves Cardiac Function and Survival in an Experimental Murine MI Model

J. Seidman, Da-Zhi Wang, W. Pu, 2014, Circulation research.

Tbx5 maintains atrial identity by regulating an atrial enhancer network

J. Seidman, W. Pu, C. Seidman, 2023, bioRxiv.

E2F3 plays an essential role in cardiac development and function

Ferhaan Ahmad, J. Seidman, J. Lees, 2008, Cell cycle.

A mutant of escherichia coli defective in removing 3′ terminal nucleotides from some transfer RNA precursor molecules

J. Seidman, F. Schmidt, W. McClain, 1975, Cell.

A classic twin study of external ear malformations, including microtia.

J. Seidman, R. Eavey, C. Seidman, 2009, The New England journal of medicine.

Advances in the Genetic Basis and Pathogenesis of Sarcomere Cardiomyopathies.

Raquel Yotti, Christine E Seidman, J. Seidman, 2019, Annual review of genomics and human genetics.

Immunoglobulin light-chain structural gene sequences cloned in a bacterial plasmid

J. Seidman, P. Leder, M. Edgell, 1978, Nature.

Short Communication: The Cardiac Myosin Binding Protein C Arg502Trp Mutation: A Common Cause of Hypertrophic Cardiomyopathy

W. Chung, J. Seidman, H. Rehm, 2010, Circulation research.

beta-Arrestin1 knockout mice appear normal but demonstrate altered cardiac responses to beta-adrenergic stimulation.

J. Seidman, S. Vatner, C. Seidman, 1997, Circulation research.

Loss of function and inhibitory effects of human CSX/NKX2.5 homeoprotein mutations associated with congenital heart disease.

J. Seidman, C. Seidman, S. Izumo, 2000, The Journal of clinical investigation.

An α-cardiac myosin heavy chain gene mutation impairs contraction and relaxation function of cardiac myocytes.

Guiping Yang, Christine E Seidman, J. Seidman, 1999, American journal of physiology. Heart and circulatory physiology.

N488I mutation of the gamma2-subunit results in bidirectional changes in AMP-activated protein kinase activity.

J. Seidman, C. Seidman, J. Ingwall, 2005, Circulation research.

Deletion of thioredoxin-interacting protein in mice impairs mitochondrial function but protects the myocardium from ischemia-reperfusion injury.

Richard T. Lee, J. Seidman, M. Lindsey, 2012, The Journal of clinical investigation.

Haploinsufficiency of MYBPC3 exacerbates the development of hypertrophic cardiomyopathy in heterozygous mice.

J. Seidman, C. Seidman, J. Gorham, 2015, Journal of molecular and cellular cardiology.

Deep Sequence Analysis of Gene Expression Identifies Osteopontin as a Downstream Effector of Integrin-Linked Kinase (ILK) in Cardiac-Specific ILK Knockout Mice

J. Seidman, R. Gerszten, S. Dedhar, 2013, Circulation. Heart failure.

Dynamic Cellular Integration Drives Functional Assembly of the Heart’s Pacemaker Complex

Christine E. Seidman, Trevor Henley, Michael Bressan, 2018, Cell reports.

CalTrack

J. Seidman, H. Watkins, A. Sparrow, 2021, Circulation research.

Mechanism based therapies enable personalised treatment of hypertrophic cardiomyopathy

J. Seidman, C. Seidman, B. Rodríguez, 2022, Scientific Reports.

Amyloid‐β proteins activate Ca2+‐permeable channels through calcium‐sensing receptors

J. Seidman, E. Brown, C. Seidman, 1997 .

Hierarchical and stage-specific regulation of murine cardiomyocyte maturation by serum response factor

J. Seidman, W. Pu, C. Seidman, 2018, Nature Communications.

Multi-Omics Profiling of Hypertrophic Cardiomyopathy Reveals Altered Mechanisms in Mitochondrial Dynamics and Excitation–Contraction Coupling

A. Emili, J. Seidman, C. Seidman, 2023, International journal of molecular sciences.

Sex differences in gene expression in response to ischemia in the human left ventricular myocardium.

J. Seidman, B. Stranger, S. Aranki, 2019, Human molecular genetics.

Small-Molecule Screen Identifies De Novo Nucleotide Synthesis as a Vulnerability of Cells Lacking SIRT3

Craig C. Benson, P. Sorger, J. Seidman, 2018, Cell reports.

Molecular genetic studies of familial hypertrophic cardiomyopathy

C. E. Seidman, J. Seidman, C. Seidman, 1998, Basic Research in Cardiology.

A dinucleotide repeat polymorphism in the MYBPH gene.

J. Seidman, C. Seidman, C. Macrae, 1994, Human Molecular Genetics.

Transcriptional Profiling of Cultured, Embryonic Epicardial Cells Identifies Novel Genes and Signaling Pathways Regulated by TGFβR3 In Vitro

J. Seidman, C. Seidman, Danos C. Christodoulou, 2016, PloS one.

Hypertrophic and dilated cardiomyopathy mutations differentially affect the molecular force generation of mouse alpha-cardiac myosin in the laser trap assay.

J B Patlak, J. Schmitt, J. Seidman, 2007, American journal of physiology. Heart and circulatory physiology.

Inherited Causes of Cardiovascular Disease

J. Seidman, C. Seidman, R. Pyeritz, 2012 .

SarcTrack

J. Seidman, O. Pourquié, Marcelo Cicconet, 2019, Circulation research.

Differential cross-bridge kinetics of FHC myosin mutations R403Q and R453C in heterozygous mouse myocardium.

Yuan Wang, Christine E Seidman, J. Schmitt, 2004, American journal of physiology. Heart and circulatory physiology.

Ventricular Arrhythmia Vulnerability in Cardiomyopathic Mice With Homozygous Mutant Myosin-Binding Protein C Gene

J. Seidman, C. Seidman, C. Berul, 2001, Circulation.

Altered cardiac excitation-contraction coupling in mutant mice with familial hypertrophic cardiomyopathy.

J. Seidman, C. Seidman, E. Marbán, 1999, The Journal of clinical investigation.

The pathogenesis of familial hypertrophic cardiomyopathy: Early and evolving effects from an α-cardiac myosin heavy chain missense mutation

Dimitrios Georgakopoulos, David A. Kass, D. Kass, 1999, Nature Medicine.

Mutations in human TBX3 alter limb, apocrine, and genital development in ulnar-mammary syndrome

J. Seidman, B. Bruneau, M. Bamshad, 1998, Nature Genetics.

Three steps in conversion of large precursor RNA into serine and proline transfer RNAs.

J. Seidman, W. McClain, 1975, Proceedings of the National Academy of Sciences of the United States of America.

Single-Gene Mutations and Increased Left Ventricular Wall Thickness in the Community: The Framingham Heart Study

D. Levy, J. Hirschhorn, J. Seidman, 2006, Circulation.

Molecular epidemiology of hypertrophic cardiomyopathy.

J. Seidman, B. Maron, C. Seidman, 2002, Cold Spring Harbor symposia on quantitative biology.

Spatial transcriptional profile of the chick and mouse endocardial cushions identify novel regulators of endocardial EMT in vitro.

J. Seidman, C. Seidman, Danos C. Christodoulou, 2013, Journal of molecular and cellular cardiology.

De novo mutations in Congenital Heart Disease with Neurodevelopmental and Other Birth Defects

Stephan J Sanders, M. Daly, W. Chung, 2016 .

Expanding the clinical and genetic spectrum of ALPK3 variants: Phenotypes identified in pediatric cardiomyopathy patients and adults with heterozygous variants.

Michael A. Burke, N. Brown, P. Lockhart, 2020, American heart journal.

Expression of a G protein subunit, alpha i-1, in Balb/c 3T3 cells leads to agonist-specific changes in growth regulation.

J. Seidman, E. Neer, T. Michel, 1991, The Journal of biological chemistry.

Structure and Expression of the Atrial Natriuretic Factor Gene

J. Seidman, C. Seidman, K. Bloch, 1987 .

Genomic analyses implicate noncoding de novo variants in congenital heart disease

Gabor T. Marth, Kathleen M. Chen, K. B. Manheimer, 2020, Nature Genetics.

A gene for non-syndromic autosomal dominant progressive postlingual sensorineural hearing loss maps to chromosome 14q12-13.

J. Seidman, S. Merchant, J. Nadol, 1996, Human molecular genetics.

Probing the subcellular nanostructure of engineered human cardiomyocytes in 3D tissue

Jourdan K. Ewoldt, J. Seidman, Christopher S. Chen, 2021, Microsystems & nanoengineering.

Genome-Wide De Novo Variants in Congenital Heart Disease Are Not Associated With Maternal Diabetes or Obesity

W. Chung, J. Seidman, Yufeng Shen, 2022, Circulation. Genomic and precision medicine.

Structure of wild-type and mutant mouse beta 2-microglobulin genes.

J. Seidman, J. Parnes, 1982, Cell.

Cao-sensing receptor (CaR)-mediated activation of K+ channels is blunted in CaR gene-deficient mouse neurons.

J. Seidman, E. Brown, C. Seidman, 1997, Neuroreport.

A gene-centric strategy for identifying disease-causing rare variants in dilated cardiomyopathy

Jacob T. Munro, J. Seidman, S. Cook, 2018, Genetics in Medicine.

The cloning of mouse globin and surrounding gene sequences in bacteriophage lambda.

J. Seidman, P. Leder, M. Edgell, 1978, Cold Spring Harbor symposia on quantitative biology.

Identification of cDNA encoding an additional alpha subunit of a human GTP-binding protein: expression of three alpha i subtypes in human tissues and cell lines.

J. Seidman, E. Neer, S. Ang, 1988, Proceedings of the National Academy of Sciences of the United States of America.

ABSENCE OF MAJOR DELETIONS OR REARRANGEMENTS OF CARDIAC MYOSIN HEAVY-CHAIN GENES IN FAMILIAL HYPERTROPHIC CARDIOMYOPATHY

J. Seidman, C. Morton, H. Watkins, 1993 .

fibrillationin animals susceptible to ventricular submaximal onset and heart rate recovery responses to Effect of endurance exercise training on heart rate

J. Seidman, G. Billman, C. Seidman, 2015 .

Missense Mutation in Human CHD4 Causes Ventricular Noncompaction by Repressing ADAMTS1

J. Seidman, J. Cook, F. Conlon, 2023, Circulation research.

Linkage of loci associated with two pigment mutations on mouse chromosome 13.

V. Chapman, J. Seidman, R. Holcombe, 1991, Genetical research.

Erratum: Dilated cardiomyopathy in homozygous myosin-binding protein-C mutant mice (Journal of Clinical Investigation (1999) 104 (1235-1244))

Richard T. Lee, D. Kass, J. Seidman, 1999 .

Contribution of Previously Unrecognized RNA Splice-Altering Variants to Congenital Heart Disease

Parth N. Patel, J. Seidman, Yufeng Shen, 2023, Circulation. Genomic and precision medicine.

EM-mosaic detects mosaic point mutations that contribute to congenital heart disease

K. B. Manheimer, W. Chung, J. Seidman, 2020, Genome Medicine.

Genetic Diagnosis of Facioscapulohumeral Muscular Dystrophy Type 1 Using Rare Variant Linkage Analysis and Long Read Genome Sequencing

P. Zhang, J. Seidman, C. Seidman, 2023, medRxiv.

M. Daly, Alex Bloemendal, J. Seidman, 2017, Nature Communications.

Prognostic implications of novel beta cardiac myosin heavy chain gene mutations that cause familial hypertrophic cardiomyopathy.

S. Solomon, J. Seidman, W. Mckenna, 1994, The Journal of clinical investigation.

Hierarchical and stage-specific regulation of murine cardiomyocyte maturation by serum response factor

J. Seidman, W. Pu, C. Seidman, 2018, Nature Communications.

A T-cell receptor gamma/CD3 complex found on cloned functional lymphocytes.

J. Seidman, J. Borst, S. Ang, 1987, Nature.

A familial hypertrophic cardiomyopathy locus maps to chromosome 15q2.

J. Seidman, A. Bowcock, W. Mckenna, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Genetic heterogeneity of heart-hand syndromes.

S. Solomon, J. Seidman, A. Poznanski, 1995, Circulation.

Superantigen-induced peripheral tolerance inhibits T cell responses to immunogenic peptides in TCR (beta-chain) transgenic mice.

J. Seidman, D. Perkins, I. Rimm, 1993, Journal of immunology.

Construction of Recombinant DNA Libraries

J. Seidman, 2003 .

Response to Brodehl et al.

J. Seidman, D. Fatkin, M. Cowley, 2018, Genetics in Medicine.

Effect of pharmacological heart failure drugs and gene therapy on Danon's cardiomyopathy.

J. Seidman, C. Seidman, R. Kornowski, 2023, Biochemical pharmacology.

Altered regulatory function of two FHC Troponin T mutants.

J. Seidman, H. Watkins, C. Seidman, 1998 .

A de novo mutation in alpha-tropomyosin that causes hypertrophic cardiomyopathy.

J. Seidman, H. Watkins, C. Seidman, 1995, Circulation.

Dilated cardiomyopathy in homozygous myosin-binding protein-C mutant mice

Jones, Kass, J. Seidman, 1999, The Journal of clinical investigation.

CORRIGENDUM: Results of clinical genetic testing of 2,912 probands with hypertrophic cardiomyopathy: expanded panels offer limited additional sensitivity

Matthew S. Lebo, J. Seidman, H. Rehm, 2015, Genetics in Medicine.

DNA-mediated transfer of major histocompatibility class II I-Ab and I-Abm12 genes into B lymphoma cells: molecular and functional analysis of introduced antigens.

J. Seidman, L. Glimcher, A. Ben-nun, 1985, Journal of immunology.

A new beta-2 microglobulin allele in mice defined by DNA sequencing

K. A. Klein, J. Seidman, D. Gasser, 2004, Immunogenetics.

endothelial enhancers and requires EP 300 activity A dynamic H 3 K 27 ac signature identifies VEGFA-stimulated Material Supplemental

Daniel S. Day, P. Park, J. Seidman, 2013 .

Cardiovascular Genomics

J. Seidman, M. Sabatine, C. Seidman, 2006, Circulation.

Allorecognition in T-cell receptor (beta-chain) transgenic mice.

J. Seidman, R. Kirkman, I. Rimm, 1991, Surgery.

Amyloid-beta proteins activate Ca(2+)-permeable channels through calcium-sensing receptors.

J. Seidman, C. Seidman, P. Vassilev, 1997, Journal of neuroscience research.

Mutations in the cardiac transcription factor NKX2.5 affect diverse cardiac developmental pathways.

J. Seidman, C. Seidman, J. Kugler, 1999, Journal of Clinical Investigation.

Clinical and Mechanistic Insights Into the Genetics of Cardiomyopathy.

Michael A. Burke, J. Seidman, S. Cook, 2016, Journal of the American College of Cardiology.

Missense mutations in the rod domain of the lamin A/C gene as causes of dilated cardiomyopathy and conduction-system disease.

J. Seidman, F. Muntoni, D. Fatkin, 1999, The New England journal of medicine.

Myofilament mechanical performance is enhanced by R403Q myosin in mouse myocardium independent of sex.

J. Seidman, Y. Wang, C. Seidman, 2008, American Journal of Physiology. Heart and Circulatory Physiology.

Clinical outcome and phenotypic expression in LAMP2 cardiomyopathy.

J. Seidman, J. Saul, W. Roberts, 2009, JAMA.

Integrated allelic, transcriptional, and phenomic dissection of the cardiac effects of titin truncations in health and disease

Tan Ru San, Angharad M Roberts, S. Gabriel, 2015, Science Translational Medicine.

Truncations of titin causing dilated cardiomyopathy.

L. Mestroni, J. Seidman, D. Pennell, 2012, The New England journal of medicine.

&bgr;-Myosin Heavy Chain Variant Val606Met Causes Very Mild Hypertrophic Cardiomyopathy in Mice, but Exacerbates HCM Phenotypes in Mice Carrying Other HCM Mutations

J. Seidman, M. Lohse, C. Seidman, 2014, Circulation research.

Genetic and environmental risk factors in congenital heart disease functionally converge in protein networks driving heart development

M. Daly, J. Rosenfeld, L. Shaffer, 2012, Proceedings of the National Academy of Sciences.

Familial hypertrophic cardiomyopathy is a genetically heterogeneous disease.

J. Seidman, C. Seidman, W. McKenna, 1990, The Journal of clinical investigation.

De novo mutations in congenital heart disease with neurodevelopmental and other congenital anomalies

Stephan J Sanders, M. Daly, W. Chung, 2015, Science.

Loss of epigenetic information as a cause of mammalian aging

Andreas R. Pfenning, Brendan L. O’Connell, Margarita V. Meer, 2023, Cell.

SARS-CoV-2 Entry Genes Are Most Highly Expressed in Nasal Goblet and Ciliated Cells within Human Airways

Fabian J Theis, D. Pe’er, A. Regev, 2020, Nature Medicine.

Whole-Genome Sequencing as a First-Line Genetic Test in Familial Dilated Cardiomyopathy

J. Seidman, D. Fatkin, M. Cowley, 2018, Genetics in Medicine.

Exercise training improves cardiac function and attenuates arrhythmia in CPVT mice.

J. Seidman, C. Seidman, M. Eldar, 2012, Journal of applied physiology.

Heterogeneous myocyte enhancer factor-2 (Mef2) activation in myocytes predicts focal scarring in hypertrophic cardiomyopathy

J. Seidman, E. Olson, C. Seidman, 2010, Proceedings of the National Academy of Sciences.

In Situ Hybridization and Immunohistochemistry

J. Seidman, 2003 .

Modeling Human TBX5 Haploinsufficiency Predicts Regulatory Networks for Congenital Heart Disease.

Joshua M. Stuart, J. Seidman, B. Bruneau, 2020, Developmental cell.

Prevention of Ventricular Arrhythmia and Calcium Dysregulation in a Catecholaminergic Polymorphic Ventricular Tachycardia Mouse Model Carrying Calsequestrin‐2 Mutation

J. Seidman, C. Seidman, C. Berul, 2011, Journal of cardiovascular electrophysiology.

T cell responses in calcineurin A alpha-deficient mice

F. Alt, J. Seidman, Jianzhu Chen, 1996, The Journal of experimental medicine.

Identification of pathogenic gene mutations in LMNA and MYBPC3 that alter RNA splicing

Parth N. Patel, J. Seidman, D. Fatkin, 2017, Proceedings of the National Academy of Sciences.

Comprehensive molecular characterization of urothelial bladder carcinoma

Evan O. Paull, Joshua M. Stuart, Richard A. Moore, 2014, Nature.

A catalogue of transfer RNA-like molecules synthesized following infection of Escherichia coli by T-even bacteriophages.

J. Seidman, W. McClain, T. Moen, 1978, The Journal of biological chemistry.

Transfer ribonucleic acid biosynthesis. Substrate specificity of ribonuclease P.

J. Seidman, F. Schmidt, R. Bock, 1976, The Journal of biological chemistry.

The biology of bacteriophage T4 transfer RNAs.

B. Barrell, J. Seidman, F. Schmidt, 1975, Brookhaven symposia in biology.

Characterization of a third form of the human T cell receptor gamma/delta

J. Seidman, J. Mclean, R. Bolli, 1988, The Journal of experimental medicine.

Screening of Recombinant DNA Libraries

J. Seidman, 2005 .

Inactivation of G-protein genes: double knockout in cell lines.

J. Seidman, R. Mortensen, 1994, Methods in enzymology.

Calcium Signaling Pathway Genes RUNX2 and CACNA1C Are Associated With Calcific Aortic Valve Disease

Y. Bossé, J. Seidman, J. Tardif, 2015, Circulation: Cardiovascular Genetics.

Alpha blockade potentiates CPVT therapy in calsequestrin-mutant mice

J. Seidman, E. Kurtzwald-Josefson, H. E. Hochhauser, 2013 .

Optimizing catecholaminergic polymorphic ventricular tachycardia therapy in calsequestrin-mutant mice.

J. Seidman, C. Seidman, M. Eldar, 2010, Heart rhythm.

Abstract 10: Cardiac-specific Yap Activation Improve Cardiac Function And Survival In An Experimental Murine Mi Model

J. Seidman, Da-Zhi Wang, W. Pu, 2014 .

Variation in the 4 q 25 Chromosomal Locus Predicts Atrial Fibrillation After Coronary Artery Bypass Graft Surgery

J. Seidman, P. Ellinor, S. Aranki, 2009 .

Whole Genome Sequencing Identifies CRISPLD2 as a Lung Function Gene in Children with asthma.

Ivana V. Yang, Andrew D. Johnson, Benjamin D. Heavner, 2019, Chest.

Harnessing Molecular Genetics for the Diagnosis and Management of Hypertrophic Cardiomyopathy

J. Seidman, C. Seidman, Libin Wang, 2010 .

Constitutively active AMP kinase mutations cause WPW and glycogen storage disease mimicking hypertrophic cardiomyopathy

J. Seidman, B. Maron, C. Seidman, 2002 .

Proatrial natriuretic factor is phosphorylated by rat cardiocytes in culture.

J. Seidman, C. Seidman, K. Bloch, 1987, The Journal of biological chemistry.