E. Dong

发表

GABAERGIC DYSFUNCTION IN SCHIZOPHRENIA: NEW TREATMENT STRATEGIES ON THE HORIZON

A. Guidotti, E. Dong, D. Grayson, 2010, Schizophrenia Research.

GABAergic dysfunction in schizophrenia: new treatment strategies on the horizon

A. Guidotti, E. Dong, D. Grayson, 2005, Psychopharmacology.

GABA(A) receptor neurotransmission dysfunction in a mouse model of social isolation-induced stress: possible insights into a non-serotonergic mechanism of action of SSRIs in mood and anxiety disorders.

E. Dong, G. Puia, Kinzo Matsumoto, 2007, Stress.

Genome-wide methylation in alcohol use disorder subjects: implications for an epigenetic regulation of the cortico-limbic glucocorticoid receptors (NR3C1)

A. Guidotti, E. Dong, D. Grayson, 2019, Molecular Psychiatry.

DNA methylation/demethylation network expression in psychotic patients with a history of alcohol abuse.

A. Guidotti, E. Dong, D. Grayson, 2013, Alcoholism, clinical and experimental research.

Acute and Protracted Prenatal Stress Produce Mood Disorder-Like and Ethanol Drinking Behaviors in Male and Female Adult Offspring

E. Dong, Alison Chu, S. Pandey, 2022, Frontiers in Behavioral Neuroscience.

Causal Roles of Stress Kinase JNK2 in DNA Methylation and Binge Alcohol Withdrawal-Evoked Behavioral Deficits.

E. Dong, Xun Ai, Jiajie Yan, 2020, Pharmacological research.

The socially-isolated mouse: a model to study the putative role of allopregnanolone and 5α-dihydroprogesterone in psychiatric disorders

A. Guidotti, E. Dong, E. Costa, 2001, Brain Research Reviews.

Increased binding of MeCP2 to the GAD1 and RELN promoters may be mediated by an enrichment of 5-hmC in autism spectrum disorder (ASD) cerebellum

E. Cook, A. Guidotti, E. Dong, 2014, Translational Psychiatry.

Brain 5α-dihydroprogesterone and allopregnanolone synthesis in a mouse model of protracted social isolation

A. Guidotti, E. Dong, E. Costa, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Involvement of diazepam binding inhibitor and its fragment octadecaneuropeptide in social isolation stress-induced decrease in pentobarbital sleep in mice.

E. Dong, Kinzo Matsumoto, Hiroshi Watanabe, 1999, Life sciences.

Diazepam binding inhibitor (DBI) gene expression in the brains of socially isolated and group-housed mice

E. Dong, Kinzo Matsumoto, Hiroshi Watanabe, 1999, Neuroscience Research.

Histone hyperacetylation induces demethylation of reelin and 67-kDa glutamic acid decarboxylase promoters

A. Guidotti, E. Dong, D. Grayson, 2007, Proceedings of the National Academy of Sciences.

The benzamide MS-275 is a potent, long-lasting brain region-selective inhibitor of histone deacetylases

A. Guidotti, E. Dong, E. Costa, 2006, Proceedings of the National Academy of Sciences of the United States of America.

Epigenetic targets in GABAergic neurons to treat schizophrenia.

A. Guidotti, E. Dong, D. Grayson, 2006, Advances in pharmacology.

Kami-shoyo-san ameliorates sociability deficits in ovariectomized mice, a putative female model of autism spectrum disorder, via facilitating dopamine D1 and GABAA receptor functions.

E. Dong, Kinzo Matsumoto, S. Awale, 2019, Journal of ethnopharmacology.

Growth Arrest and DNA-Damage-Inducible, Beta (GADD45b)-Mediated DNA Demethylation in Major Psychosis

A. Guidotti, E. Dong, Rajiv P. Sharma, 2012, Neuropsychopharmacology.

Gestational stress induces depressive-like and anxiety-like phenotypes through epigenetic regulation of BDNF expression in offspring hippocampus

E. Dong, Xianquan Zhang, Yu Zheng, 2016, Epigenetics.

N-Phthalyl-l-Tryptophan (RG108), like Clozapine (CLO), Induces Chromatin Remodeling in Brains of Prenatally Stressed Mice

A. Guidotti, E. Dong, D. Grayson, 2018, Molecular Pharmacology.

Epigenetics: From basic biology to chromatin-modifying drugs and new potential clinical applications

A. Guidotti, E. Dong, D. Grayson, 2016 .

Reviewing the Role of DNA (Cytosine-5) Methyltransferase Overexpression in the Cortical GABAergic Dysfunction Associated with Psychosis Vulnerability

A. Guidotti, E. Dong, D. Grayson, 2007, Epigenetics.

In socially isolated mice, the reversal of brain allopregnanolone down-regulation mediates the anti-aggressive action of fluoxetine

A. Guidotti, E. Dong, E. Costa, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Valproate corrects the schizophrenia-like epigenetic behavioral modifications induced by methionine in mice

A. Guidotti, E. Dong, D. Grayson, 2005, Biological Psychiatry.

Analysis of the GAD1 promoter: Trans-acting factors and DNA methylation converge on the 5′ untranslated region

E. Dong, D. Grayson, Ying Chen, 2011, Neuropharmacology.

Laboratory epigenetic models of schizophrenia

E. Dong, D. Grayson, J. Peedicayil, 2021, Epigenetics in Psychiatry.

GABAergic promoter hypermethylation as a model to study the neurochemistry of schizophrenia vulnerability

A. Guidotti, E. Dong, D. Grayson, 2009, Expert review of neurotherapeutics.

A reelin–integrin receptor interaction regulates Arc mRNA translation in synaptoneurosomes

A. Guidotti, E. Dong, D. Grayson, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Epigenetic GABAergic targets in schizophrenia and bipolar disorder

A. Guidotti, E. Dong, D. Grayson, 2011, Neuropharmacology.

Characterization of the action of antipsychotic subtypes on valproate-induced chromatin remodeling.

A. Guidotti, E. Dong, D. Grayson, 2009, Trends in pharmacological sciences.

REELIN and schizophrenia: a disease at the interface of the genome and the epigenome.

A. Guidotti, E. Dong, D. Grayson, 2002, Molecular interventions.

Prenatal stress induced chromatin remodeling and risk of psychopathology in adulthood.

E. Dong, S. Pandey, Erbo Dong, 2021, International review of neurobiology.

Reelin and glutamic acid decarboxylase67 promoter remodeling in an epigenetic methionine-induced mouse model of schizophrenia.

A. Guidotti, E. Dong, D. Grayson, 2005, Proceedings of the National Academy of Sciences of the United States of America.

DNA-methyltransferase1 (DNMT1) binding to CpG rich GABAergic and BDNF promoters is increased in the brain of schizophrenia and bipolar disorder patients

A. Guidotti, E. Dong, D. Grayson, 2015, Schizophrenia Research.

DNA-methylation gene network dysregulation in peripheral blood lymphocytes of schizophrenia patients

A. Lajtha, A. Guidotti, E. Dong, 2013, Schizophrenia Research.

Activation of Group II Metabotropic Glutamate Receptors Promotes DNA Demethylation in the Mouse Brain

A. Guidotti, E. Dong, F. Nicoletti, 2011, Molecular Pharmacology.

Antipsychotic subtypes can be characterized by differences in their ability to modify GABAergic promoter methylation.

A. Guidotti, E. Dong, D. Grayson, 2009, Epigenomics.

From trans-methylation to cytosine methylation: Evolution of the methylation hypothesis of schizophrenia

A. Guidotti, E. Dong, D. Grayson, 2009, Epigenetics.

Upregulation of TET1 and downregulation of APOBEC3A and APOBEC3C in the parietal cortex of psychotic patients

John D. Davis, E. Dong, D. Gavin, 2012, Translational Psychiatry.

The human reelin gene: transcription factors (+), repressors (-) and the methylation switch (+/-) in schizophrenia.

A. Guidotti, E. Dong, D. Grayson, 2006, Pharmacology & therapeutics.

Behavioral and molecular neuroepigenetic alterations in prenatally stressed mice: relevance for the study of chromatin remodeling properties of antipsychotic drugs

A. Guidotti, E. Dong, D. Grayson, 2016, Translational psychiatry.

Brain-Derived Neurotrophic Factor Epigenetic Modifications Associated with Schizophrenia-like Phenotype Induced by Prenatal Stress in Mice

Patricia Tueting, A. Guidotti, E. Dong, 2015, Biological Psychiatry.

Toward the Identification of Peripheral Epigenetic Biomarkers of Schizophrenia

A. Guidotti, E. Dong, D. Grayson, 2014, Journal of neurogenetics.

Clozapine and sulpiride but not haloperidol or olanzapine activate brain DNA demethylation

A. Guidotti, E. Dong, D. Grayson, 2008, Proceedings of the National Academy of Sciences.

Valproate induces DNA demethylation in nuclear extracts from adult mouse brain

A. Guidotti, E. Dong, D. Grayson, 2010, Epigenetics.

Maternal immune activation induces GAD1 and GAD2 promoter remodeling in the offspring prefrontal cortex

A. Guidotti, E. Dong, D. Grayson, 2015, Epigenetics.

Selective α4β2 Nicotinic Acetylcholine Receptor Agonists Target Epigenetic Mechanisms in Cortical GABAergic Neurons

A. Guidotti, E. Dong, B. Kadriu, 2011, Neuropsychopharmacology.

A GABAergic cortical deficit dominates schizophrenia pathophysiology.

A. Guidotti, E. Dong, D. Grayson, 2004, Critical reviews in neurobiology.

GABAA receptor neurotransmission dysfunction in a mouse model of social isolation-induced stress: Possible insights into a non-serotonergic mechanism of action of SSRIs in mood and anxiety disorders

E. Dong, G. Puia, Kinzo Matsumoto, 2007 .

Modeling the molecular epigenetic profile of psychosis in prenatally stressed mice.

A. Guidotti, E. Dong, D. Grayson, 2014, Progress in molecular biology and translational science.

Reelin Downregulation as a Prospective Treatment Target for GABAergic Dysfunction in Schizophrenia

A. Guidotti, E. Dong, D. Grayson, 2008 .

Deficits of Hippocampal RNA Editing and Social Interaction Resulting from Prenatal Stress are Mitigated by Clozapine

A. Guidotti, E. Dong, S. Gentile, 2021, bioRxiv.

Genipin normalizes depression-like behavior induced by prenatal stress through inhibiting DNMT1

E. Dong, Xianquan Zhang, W. Fan, 2018, Epigenetics.

Chapter 2 Epigenetic Regulation of GABAergic Targets in Psychiatry

A. Guidotti, E. Dong, D. Grayson, 2018 .

Epigenetic Regulation of GABAergic Targets in Psychiatry

A. Guidotti, E. Dong, D. Grayson, 2011 .

Involvement of peripheral type of benzodiazepine receptor in social isolation stress-induced decrease in pentobarbital sleep in mice.

E. Dong, Kinzo Matsumoto, H. Watanabe, 1999, Life sciences.

Prenatal stress leads to chromatin and synaptic remodeling and excessive alcohol intake comorbid with anxiety-like behaviors in adult offspring

A. Guidotti, E. Dong, S. Pandey, 2018, Neuropharmacology.

Epigenetic Alterations in Prenatal Stress Mice as an Endophenotype Model for Schizophrenia: Role of Metabotropic Glutamate 2/3 Receptors

A. Guidotti, E. Dong, F. Nicoletti, 2018, Front. Mol. Neurosci..

Diazepam binding inhibitor (DBI) reduces testosterone and estradiol levels in vivo.

E. Dong, Kinzo Matsumoto, H. Watanabe, 2002, Life Science.

BDNF epigenetic modifications associated with schizophrenia-like phenotype induced by prenatal stress in mice

A. Guidotti, E. Dong, P. Tueting, 2015 .

Altered Expression and in vivo Activity of mGlu5 variant a Receptors in the striatum of BTBR mice: Novel insights into the pathophysiology of adult idiopathic forms of autism spectrum disorders.

A. Guidotti, E. Dong, D. Grayson, 2022, Current neuropharmacology.

GABAergic promoter hypermethylation as a model to study the neurochemistry of schizophrenia vulnerability

A. Guidotti, E. Dong, D. Grayson, 2009, Expert review of neurotherapeutics.