J. Connolly

发表

Dendritic cell subsets in health and disease

H. Ueno, E. Klechevsky, R. Morita, 2007, Immunological reviews.

Stimulation Do Not Alter TTP Function Protein Kinase and Lipopolysaccharide Tristetraprolin ( TTP ) : p 38 Stress-Activated Structure / Function Analysis of

J. Connolly, J. Collins, D. Bloch, 2005 .

Structure/Function Analysis of Tristetraprolin (TTP): p38 Stress-Activated Protein Kinase and Lipopolysaccharide Stimulation Do Not Alter TTP Function1

J. Connolly, J. Collins, D. Bloch, 2005, Journal of Immunology.

Autoregulatory Pathway Signal-Regulated Kinase-Specific , AURich Evidence for an Extracellular Regulation of Tristetraprolin Expression : The Role of mRNA Turnover in the

J. Connolly, S. Brooks, W. Rigby, 2004 .

Analysis of the function, expression, and subcellular distribution of human tristetraprolin.

J. Connolly, S. Brooks, W. Rigby, 2002, Arthritis and rheumatism.

Immunological corollary of the pulmonary mycobiome in bronchiectasis: the CAMEB study

S. Matta, Y. Sio, F. Chew, 2018, European Respiratory Journal.

Epigenomic Promoter Alterations Amplify Gene Isoform and Immunogenic Diversity in Gastric Adenocarcinoma.

J. Connolly, K. Soo, H. Ong, 2017, Cancer discovery.

Safety and immunogenicity of a virus-like particle pandemic influenza A (H1N1) 2009 vaccine: results from a double-blinded, randomized Phase I clinical trial in healthy Asian volunteers.

J. Connolly, S. Maurer-Stroh, J. Low, 2014, Vaccine.

Monocytic Myeloid-Derived Suppressor Cells Underpin Resistance to Adoptive T Cell Therapy in Nasopharyngeal Carcinoma

J. Connolly, Bernett Lee, A. Lezhava, 2020, Molecular therapy : the journal of the American Society of Gene Therapy.

Glomerulonephritisin Autoantibody-Mediated Disease Renal Cells May Promote End-Organ Type I Interferons Produced by Resident

J. Connolly, C. Mohan, E. Wakeland, 2009 .

Type I Interferons Produced by Resident Renal Cells May Promote End-Organ Disease in Autoantibody-Mediated Glomerulonephritis1

J. Connolly, C. Mohan, E. Wakeland, 2009, The Journal of Immunology.

Germline NLRP1 Mutations Cause Skin Inflammatory and Cancer Susceptibility Syndromes via Inflammasome Activation

E. Lane, J. Connolly, M. Akiyama, 2016, Cell.

Immune and Clinical Outcomes in Patients with Stage IV Melanoma Vaccinated with Peptide-Pulsed Dendritic Cells Derived From CD34+ Progenitors and Activated with Type I Interferon

H. Ueno, E. Klechevsky, J. Connolly, 2005, Journal of immunotherapy.

TLR7 and TLR9 ligands regulate antigen presentation by macrophages.

J. Connolly, M. Poidinger, S. Biswas, 2016, International immunology.

Brief report: Decreased expression of CD244 (SLAMF4) on monocytes and platelets in patients with systemic lupus erythematosus

J. Connolly, Bernett Lee, M. Poidinger, 2017, Clinical Rheumatology.

Monocyte Siglec-14 expression is upregulated in patients with systemic lupus erythematosus and correlates with lupus disease activity

J. Connolly, Bernett Lee, M. Poidinger, 2017, Rheumatology.

Disease in Systemic Lupus Erythematosus Autoantibody Production and Exacerbates B Cell TLR7 Expression Drives Anti-RNA

J. Connolly, E. Wakeland, A. Fairhurst, 2012 .

B Cell TLR7 Expression Drives Anti-RNA Autoantibody Production and Exacerbates Disease in Systemic Lupus Erythematosus–Prone Mice

J. Connolly, M. A. Curotto de Lafaille, E. Wakeland, 2012, The Journal of Immunology.

Toll‐Like Receptor 9 Deficiency Breaks Tolerance to RNA‐Associated Antigens and Up‐Regulates Toll‐Like Receptor 7 Protein in Sle1 Mice

B. Au, J. Connolly, T. Thamboo, 2018, Arthritis & rheumatology.

Aqueous humor immune factors and cytomegalovirus (CMV) levels in CMV retinitis through treatment - The CRIGSS study.

J. Connolly, S. Teoh, R. Agrawal, 2016, Cytokine.

Dataset of aqueous humor cytokine profile in HIV patients with Cytomegalovirus (CMV) retinitis

J. Connolly, S. Teoh, R. Agrawal, 2016, Data in brief.

Dataset of tear film cytokine levels in dry eye disease (DED) patients with and without HIV infection

J. Connolly, S. Teoh, R. Agrawal, 2016, Data in brief.

Bead Based Multiplex Assay for Analysis of Tear Cytokine Profiles.

J. Connolly, R. Agrawal, L. Tong, 2017, Journal of visualized experiments : JoVE.

Dataset of longitudinal analysis of tear cytokine levels, CD4, CD8 counts and HIV viral load in dry eye patients with HIV infection

J. Connolly, S. Teoh, R. Agrawal, 2017, Data in brief.

A distinct cytokines profile in tear film of dry eye disease (DED) patients with HIV infection.

J. Connolly, S. Teoh, R. Agrawal, 2016, Cytokine.

Met-Flow, a strategy for single-cell metabolic analysis highlights dynamic changes in immune subpopulations

B. Au, J. Connolly, A. Fairhurst, 2020, Communications Biology.

Distinct “Immunoallertypes” of Disease and High Frequencies of Sensitization in Non‐Cystic Fibrosis Bronchiectasis

S. Matta, Y. Sio, F. Chew, 2019, American journal of respiratory and critical care medicine.

Dose- and schedule-dependent protective efficacy of celgosivir in a lethal mouse model for dengue virus infection informs dosing regimen for a proof of concept clinical trial.

J. Connolly, S. Vasudevan, E. Ooi, 2012, Antiviral research.

Induction of Human T-cell and Cytokine Responses Following Vaccination with a Novel Influenza Vaccine

B. Au, J. Connolly, J. Low, 2018, Scientific Reports.

The walking dead: sequential nuclear and organelle destruction during hair development

J. Connolly, D. Harland, B. Jarrold, 2018, The British journal of dermatology.

Cytokines and Biologics in non-infectious autoimmune uveitis: Bench to Bedside

J. Connolly, S. Teoh, R. Agrawal, 2014, Indian journal of ophthalmology.

Generation of Immature, Mature and Tolerogenic Dendritic Cells with Differing Metabolic Phenotypes.

J. Connolly, A. Fairhurst, W. Sim, 2016, Journal of visualized experiments : JoVE.

LAG3 is a Central Regulator of NK Cell Cytokine Production

J. Connolly, Sriram Narayanan, S. Lim, 2020, bioRxiv.

Evidence for Induced Expression of HLA Class II on Human Islets: Possible Mechanism for HLA Sensitization in Transplant Recipients

J. Connolly, M. Levy, B. Naziruddin, 2009, Transplantation.

Hyperthermia Enhances CTL Cross-Priming1

Tinghua Cao, J. Connolly, J. Banchereau, 2006, The Journal of Immunology.

Thrombin and Chymotrypsin Interactions with Thrombospondin a

J. Connolly, J. Lawler, L. Derick, 1986, Annals of the New York Academy of Sciences.

TLR7 Protein Expression in Mild and Severe Lupus-Prone Models Is Regulated in a Leukocyte, Genetic, and IRAK4 Dependent Manner

B. Au, J. Connolly, T. Thamboo, 2019, Front. Immunol..

A multicenter phase II randomized trial of durvalumab (MEDI-4736) versus physician’s choice chemotherapy in recurrent ovarian clear cell adenocarcinoma (MOCCA)

Jae-Weon Kim, J. Connolly, M. Friedlander, 2020, International Journal of Gynecological Cancer.

A Perspective on Cell Therapy and Cancer Vaccine in Biliary Tract Cancers (BTCs)

J. Connolly, H. Toh, Richard A. Hopkins, 2020, Cancers.

Spontaneous Proliferation and Type 2 Cytokine Secretion by CD4+T Cells in Patients with Metastatic Melanoma Vaccinated with Antigen-Pulsed Dendritic Cells

H. Ueno, J. Connolly, J. Fay, 2005, Journal of Clinical Immunology.

Extended Evaluation of Virological, Immunological and Pharmacokinetic Endpoints of CELADEN: A Randomized, Placebo-Controlled Trial of Celgosivir in Dengue Fever Patients

Uma S. Kamaraj, P. D. de Sessions, J. Connolly, 2016, PLoS neglected tropical diseases.

Singapore Ocular Tuberculosis Immunity Study (SPOTIS): Role of T-lymphocyte Profiling in Patients with Presumed Ocular Tuberculosis

J. Connolly, R. Agrawal, P. Hutchinson, 2020, Ocular immunology and inflammation.

Enhancing Antigen Cross-Presentation in Human Monocyte-Derived Dendritic Cells by Recruiting the Intracellular Fc Receptor TRIM21

J. Connolly, Q. Tan, Cheng‐I Wang, 2019, The Journal of Immunology.

Optimal cellular preservation for high dimensional flow cytometric analysis of multicentre trials.

J. Connolly, Bernett Lee, M. Poidinger, 2012, Journal of immunological methods.

Physiological Doses of Red Light Induce IL‐4 Release in Cocultures between Human Keratinocytes and Immune Cells

J. Connolly, G. Sriram, P. Bigliardi, 2018, Photochemistry and photobiology.

A Novel Human Cancer Vaccine Elicits Cellular Responses to the Tumor-Associated Antigen, Human Chorionic Gonadotropin β

J. Connolly, M. Endres, P. Wallace, 2004, Clinical Cancer Research.

Lack of Recall Response to Tax in ATL and HAM/TSP Patients But Not in Asymptomatic Carriers of Human T-cell Leukemia Virus Type 1

J. Connolly, M. Betts, Sharrón L Manuel, 2013, Journal of Clinical Immunology.

Motavizumab, A Neutralizing Anti-Respiratory Syncytial Virus (Rsv) Monoclonal Antibody Significantly Modifies The Local And Systemic Cytokine Responses Induced By Rsv In The Mouse Model

J. Connolly, O. Ramilo, A. Mejias, 2007, Virology Journal.

Extraction of osmium zinc iodide staining material in keratinosomes.

J. Connolly, W. Krawczyk, G. Wilgram, 1973, The Journal of investigative dermatology.

A chimeric receptor with NKG2D specificity enhances natural killer cell activation and killing of tumor cells.

D. Campana, J. Connolly, Yu-Hsiang Chang, 2013, Cancer research.

The structure of human platelet thrombospondin.

J. Connolly, J. Lawler, J. Chen, 1985, The Journal of biological chemistry.

RNA sensing by conventional dendritic cells is central to the development of lupus nephritis

J. Connolly, T. Thamboo, E. Wakeland, 2015, Proceedings of the National Academy of Sciences.

CD2 Distinguishes Two Subsets of Human Plasmacytoid Dendritic Cells with Distinct Phenotype and Functions1

T. Matsui, J. Connolly, J. Banchereau, 2009, The Journal of Immunology.

Dendritic Cells: Biological and Pathological Aspects

H. Ueno, E. Klechevsky, J. Connolly, 2008 .

Human Dendritic Cell Subsets for Vaccination

H. Ueno, J. Connolly, A. Palucka, 2005, Journal of Clinical Immunology.

25th Anniversary Edition: Human Dendritic Cell Subsets for Vaccination

H. Ueno, J. Connolly, J. Banchereau, 2005 .

Enhanced Neutralizing Antibody Titers and Th1 Polarization from a Novel Escherichia coli Derived Pandemic Influenza Vaccine

B. Au, J. Connolly, Bernett Lee, 2013, PloS one.

Cytokine analysis of aqueous humor in HIV patients with cytomegalovirus retinitis.

B. Au, J. Connolly, S. Teoh, 2013, Cytokine.

Efficacy and safety of celgosivir in patients with dengue fever (CELADEN): a phase 1b, randomised, double-blind, placebo-controlled, proof-of-concept trial.

J. Connolly, J. Low, Y. Cheung, 2014, The Lancet. Infectious diseases.

Celgosivir treatment misfolds dengue virus NS1 protein, induces cellular pro-survival genes and protects against lethal challenge mouse model.

J. Connolly, S. Vasudevan, E. Ooi, 2011, Antiviral research.

Netting Neutrophils Are Major Inducers of Type I IFN Production in Pediatric Systemic Lupus Erythematosus

J. Connolly, V. Pascual, J. Banchereau, 2011, Science Translational Medicine.

Dominant-negative NFKBIA mutation promotes IL-1β production causing hepatic disease with severe immunodeficiency.

Chang Siang Lim, F. Ginhoux, J. Connolly, 2020, The Journal of clinical investigation.

Chromosomal instability-induced senescence potentiates cell non-autonomous tumourigenic effects

B. Au, J. Connolly, Zhiyan Fu, 2018, Oncogenesis.

Human Tissues Contain CD141hi Cross-Presenting Dendritic Cells with Functional Homology to Mouse CD103+ Nonlymphoid Dendritic Cells

Michael Poidinger, Rachel Dickinson, Antonio Bertoletti, 2012, Immunity.

Functional Role for IκBNS in T Cell Cytokine Regulation As Revealed by Targeted Gene Disruption1

M. Kumar, J. Connolly, D. Keskin, 2007, The Journal of Immunology.

The specialized roles of immature and mature dendritic cells in antigen cross-presentation

J. Connolly, Richard A. Hopkins, 2012, Immunologic Research.

Direct proteasome-independent cross-presentation of viral antigen by plasmacytoid dendritic cells on major histocompatibility complex class I

J. Connolly, J. Banchereau, I. Mellman, 2008, Nature Immunology.

Disruption of E-cadherin-mediated adhesion induces a functionally distinct pathway of dendritic cell maturation.

J. Connolly, J. Banchereau, I. Mellman, 2007, Immunity.

Upon viral exposure, myeloid and plasmacytoid dendritic cells produce 3 waves of distinct chemokines to recruit immune effectors.

J. Connolly, J. Banchereau, B. Piqueras, 2006, Blood.

Dendritic Cell and Pathogen Interactions in the Subversion of Protective Immunity

J. Connolly, J. Banchereau, Damien Chaussabe, 2007 .

Multiplex Serum Protein Analysis Identifies Novel Biomarkers of Advanced Fibrosis in Patients with Chronic Liver Disease with the Potential to Improve Diagnostic Accuracy of Established Biomarkers

J. Connolly, Bernett Lee, K. Irvine, 2016, PloS one.

Characterization of Fetal Keratinocytes, Showing Enhanced Stem Cell-Like Properties: A Potential Source of Cells for Skin Reconstruction

E. Lane, J. Connolly, J. Chan, 2014, Stem cell reports.

Adoptive T-cell Transfer and Chemotherapy in the First-line Treatment of Metastatic and/or Locally Recurrent Nasopharyngeal Carcinoma

J. Connolly, Y. Cheung, E. Tan, 2013, Molecular therapy : the journal of the American Society of Gene Therapy.

Leukocyte immunoglobulin-like receptor B1 is critical for antibody-dependent dengue

J. Connolly, Manoj N. Krishnan, S. Lok, 2014, Proceedings of the National Academy of Sciences.

Immunohistochemical scoring of CD38 in the tumor microenvironment predicts responsiveness to anti-PD-1/PD-L1 immunotherapy in hepatocellular carcinoma

B. Au, J. Connolly, P. Chow, 2020, Journal for ImmunoTherapy of Cancer.

Human DPP9 represses NLRP1 inflammasome and protects against autoinflammatory diseases via both peptidase activity and FIIND domain binding

J. Connolly, John Calvin Reed, S. Masters, 2018, The Journal of Biological Chemistry.

DPP9 is an endogenous and direct inhibitor of the NLRP1 inflammasome that guards against human auto-inflammatory diseases

J. Connolly, S. Masters, F. Zhong, 2018, bioRxiv.

Dendritic Cells Loaded With Killed Allogeneic Melanoma Cells can Induce Objective Clinical Responses and MART-1 Specific CD8+ T-cell Immunity

H. Ueno, J. Connolly, J. Fay, 2006, Journal of immunotherapy.

Lactate Dehydrogenase Is an AU-rich Element-binding Protein That Directly Interacts with AUF1*

Gary Brewer, J. Connolly, G. Brewer, 2002, The Journal of Biological Chemistry.

IRF-7 Mediates Type I IFN Responses in Endotoxin-Challenged Mice

J. Connolly, I. Su, T. J. Lim, 2020, Frontiers in Immunology.

Mannose Receptor Targeting of Tumor Antigen pmel17 to Human Dendritic Cells Directs Anti-Melanoma T Cell Responses via Multiple HLA Molecules

J. Connolly, M. Endres, P. Wallace, 2004, The Journal of Immunology.

Lack of recall response to Tax in ATL and HAM/TSP patients but not in asymptomatic carriers of human T-cell leukemia virus type 1

J. Goedert, J. Connolly, M. Betts, 2014, Retrovirology.

The Role of mRNA Turnover in the Regulation of Tristetraprolin Expression: Evidence for an Extracellular Signal-Regulated Kinase-Specific, AU-Rich Element-Dependent, Autoregulatory Pathway1

J. Connolly, Seth A. Brooks, John E. Connolly, 2004, The Journal of Immunology.

Genome-wide analysis of the genetic regulation of gene expression in human neutrophils

J. Connolly, Jianjun Liu, A. Irwanto, 2015, Nature Communications.

Intraperitoneal immunotherapy with T cells stably and transiently expressing anti-EpCAM CAR in xenograft models of peritoneal carcinomatosis

J. Connolly, Shu Wang, H. Toh, 2017, Oncotarget.

A novel strategy for single-cell metabolic analysis highlights dynamic changes in immune subpopulations

B. Au, J. Connolly, A. Fairhurst, 2020, bioRxiv.

Metabolism Is Central to Tolerogenic Dendritic Cell Function

J. Connolly, W. Sim, Patricia J. Ahl, 2016, Mediators of inflammation.

High Mitochondrial Respiration and Glycolytic Capacity Represent a Metabolic Phenotype of Human Tolerogenic Dendritic Cells

J. Connolly, M. Poidinger, Kaibo Duan, 2015, The Journal of Immunology.

Systematic characterization of basophil anergy

F. Chew, J. Connolly, A. Andiappan, 2017, Allergy.

Effective Killing of Acute Myeloid Leukemia by TIM-3 Targeted Chimeric Antigen Receptor T Cells

J. Connolly, C. Chuah, Mun Kuen Soh, 2021, Molecular Cancer Therapeutics.

Citrullinated peptide dendritic cell immunotherapy in HLA risk genotype–positive rheumatoid arthritis patients

Ahmed M. Mehdi, J. Connolly, S. Paul, 2015, Science Translational Medicine.

Bayesian analysis of cytokines and chemokine identifies immune pathways of HBsAg loss during chronic hepatitis B treatment

J. Connolly, Sriram Narayanan, Bernett Lee, 2021, Scientific Reports.

Differential Expression of Toll-Like Receptors 2 and 4 in Tissues of the Human Female Reproductive Tract

J. Connolly, Eyal Amiel, P. Guyre, 2004, Infection and Immunity.

Differential recruitment of dendritic cells and monocytes to respiratory mucosal sites in children with influenza virus or respiratory syncytial virus infection.

J. Connolly, J. Banchereau, O. Ramilo, 2008, The Journal of infectious diseases.

Regulation and localization of endogenous human tristetraprolin

J. Connolly, P. Wallace, A. Fairhurst, 2003, Arthritis research & therapy.

Unique Cytokine/Chemokine Signatures for HIV-1 and HCV Mono-infection versus Co-infection as Determined by the Luminex® Analyses.

J. Connolly, S. Rahman, L. Montaner, 2011, Journal of clinical & cellular immunology.

Linked Immuno Sorbent Assay; GM-CSF: Granulocyte-Macrophage Colony-Stimulating Factor; HAART: Highly Active Antiretroviral Therapy; HCV: Hepatitis C Virus; HIV-1: Human Immunodeficiency Virus; IDU: Intravenous Drug User; IFN: Interferon; IL: Interleukin; MCP-1: Monocyte Chemoattractant Protein; MIP-

J. Connolly, S. Rahman, L. Montaner, 2011 .

Cytokine Profiling in Patients With Exudative Age-Related Macular Degeneration and Polypoidal Choroidal Vasculopathy.

J. Connolly, R. Agrawal, Bernett Lee, 2019, Investigative ophthalmology & visual science.

Personal level exposure and hazard potential of particulate matter during haze and non-haze periods in Singapore.

J. Connolly, C. Yung, O. Teoh, 2020, Chemosphere.

Allergic airway diseases in a tropical urban environment are driven by dominant mono-specific sensitization against house dust mites

F. Chew, J. Connolly, D. Wang, 2014, Allergy.

Tetravalent dengue DIIIC protein together with alum and ODN elicits a Th1 response and neutralizing antibodies in mice.

J. Connolly, K. Fink, G. Guillén, 2015, Vaccine.

Cytokine profiling in patients with exudative age-related macular degeneration due to choroidal neovascularization and polypoidal choroidal vasculopathy

J. Connolly, R. Agrawal, Bernett Lee, 2018 .

Immuno-allertypes in non-cystic fibrosis bronchiectasis

Y. Sio, F. Chew, J. Connolly, 2018, Allergy and immunology.

Cytokine Profiling in Patients With Exudative Age-Related Macular Degeneration and Polypoidal Choroidal Vasculopathy.

J. Connolly, Bernett Lee, Arkasubhra Ghosh, 2019, Investigative ophthalmology & visual science.

Dataset of plasma and aqueous humor cytokine profiles in patients with exudative age related macular degeneration and polypoidal choroidal vasculopathy

J. Connolly, Bernett Lee, Arkasubhra Ghosh, 2018, Data in brief.

A multicenter phase II randomized trial of durvalumab (D) versus physician’s choice chemotherapy (PCC) in patients (pts) with recurrent ovarian clear cell adenocarcinoma (MOCCA/APGOT-OV2/GCGS-OV3).

Jae-Weon Kim, J. Connolly, C. Choi, 2022, Journal of Clinical Oncology.