C. Culmsee

发表

Nuclear Translocation of Apoptosis-Inducing Factor after Focal Cerebral Ischemia

N. Plesnila, Changlian Zhu, C. Culmsee, 2004, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Purification of polyethylenimine polyplexes highlights the role of free polycations in gene transfer

C. Culmsee, Sabine Boeckle, M. Ogris, 2004, The journal of gene medicine.

Proteomic analysis reveals differences in protein expression in spheroid versus monolayer cultures of low-passage colon carcinoma cells.

C. Culmsee, B. Mayer, E. Wagner, 2007, Journal of proteome research.

Central Inhibition of IKKβ/NF-κB Signaling Attenuates High-Fat Diet–Induced Obesity and Glucose Intolerance

C. Culmsee, L. M. Williams, C. Koch, 2015, Diabetes.

A brain-specific isoform of mitochondrial apoptosis-inducing factor: AIF2

P. Bénit, C. Culmsee, K. Blomgren, 2010, Cell Death and Differentiation.

Enantio-selective effects of clenbuterol in cultured neurons and astrocytes, and in a mouse model of cerebral ischemia.

N. Plesnila, C. Culmsee, H. Schneider, 2007, European journal of pharmacology.

Cellular and Molecular Mechanisms Underlying Perturbed Energy Metabolism and Neuronal Degeneration in Alzheimer's and Parkinson's Diseases

C. Culmsee, M. Mattson, W. Duan, 1999, Annals of the New York Academy of Sciences.

Interaction of the Psychiatric Risk Gene Cacna1c With Post-weaning Social Isolation or Environmental Enrichment Does Not Affect Brain Mitochondrial Bioenergetics in Rats

M. Rietschel, C. Culmsee, R. Schwarting, 2019, Front. Cell. Neurosci..

Downregulation of the psychiatric susceptibility gene Cacna1c promotes mitochondrial resilience to oxidative stress in neuronal cells

C. Culmsee, R. Schwarting, M. Wöhr, 2018, Cell Death Discovery.

Psychiatric risk gene Cacna1c determines mitochondrial resilience against oxidative stress in neurons

C. Culmsee, R. Schwarting, M. Wöhr, 2018, Cell Death & Disease.

Emerging pharmacotherapeutic strategies for the treatment of ischemic stroke

C. Culmsee, J. Krieglstein, 2006 .

Lubeluzole protects hippocampal neurons from excitotoxicity in vitro and reduces brain damage caused by ischemia.

C. Culmsee, J. Krieglstein, I. Semkova, 1998, European journal of pharmacology.

Glutathione peroxidase 4 senses and translates oxidative stress into 12/15-lipoxygenase dependent- and AIF-mediated cell death.

N. Plesnila, C. Culmsee, W. Wurst, 2008, Cell metabolism.

Enalapril and moexipril protect from free radical-induced neuronal damage in vitro and reduce ischemic brain injury in mice and rats.

C. Culmsee, B. Ahlemeyer, J. Krieglstein, 1999, European journal of pharmacology.

N‐Acyl Derivatives of 4‐Phenoxyaniline as Neuroprotective Agents

C. Culmsee, M. Schlitzer, S. Oppermann, 2014, ChemMedChem.

Parkin Mediates Neuroprotection through Activation of IκB Kinase/Nuclear Factor-κB Signaling

C. Culmsee, B. Berninger, D. Krappmann, 2007, The Journal of Neuroscience.

Metabolic switch induced by Cimicifuga racemosa extract prevents mitochondrial damage and oxidative cell death.

C. Culmsee, J. Drewe, M. Unger, 2019, Phytomedicine : international journal of phytotherapy and phytopharmacology.

Statins — increasing or reducing the risk of Parkinson's disease?

C. Culmsee, W. Oertel, A. Dolga, 2011, Experimental Neurology.

Inhibition of HIF-prolyl-4-hydroxylases prevents mitochondrial impairment and cell death in a model of neuronal oxytosis

C. Culmsee, R. Ratan, A. Dolga, 2016, Cell Death and Disease.

Protamine Sulfate Induces Mitochondrial Hyperpolarization and a Subsequent Increase in Reactive Oxygen Species Production

C. Culmsee, P. Weber, S. Vogt, 2019, The Journal of Pharmacology and Experimental Therapeutics.

Egr-1 regulates expression of the glial scar component phosphacan in astrocytes after experimental stroke.

N. Plesnila, C. Culmsee, A. Hatzopoulos, 2008, The American journal of pathology.

Effects of Raf-1 siRNA on human cerebral microvascular endothelial cells: A potential therapeutic strategy for inhibition of tumor angiogenesis

C. Culmsee, E. Wagner, R. Goldbrunner, 2006, Brain Research.

Extracellular Alpha-Synuclein Oligomers Induce Parkin S-Nitrosylation: Relevance to Sporadic Parkinson’s Disease Etiopathology

C. Culmsee, A. Adamczyk, R. Brodzik, 2018, Molecular Neurobiology.

Aberrant stress response associated with severe hypoglycemia in a transgenic mouse model of Alzheimer’s disease

C. Culmsee, M. Mattson, J. Herman, 1999, Journal of Molecular Neuroscience.

Elevated hepatic and depressed renal cytochrome P450 activity in the Tg2576 transgenic mouse model of Alzheimer's disease

C. Culmsee, M. Mattson, M. Mattson, 2002, Journal of neurochemistry.

Corticotropin-Releasing Hormone Protects Neurons against Insults Relevant to the Pathogenesis of Alzheimer's Disease

C. Culmsee, M. Mattson, J. Herman, 2001, Neurobiology of Disease.

Actin(g) on mitochondria – a role for cofilin1 in neuronal cell death pathways

C. Culmsee, M. Rust, L. Hoffmann, 2019, Biological chemistry.

Transglutaminases factor XIII-A and TG2 regulate resorption, adipogenesis and plasma fibronectin homeostasis in bone and bone marrow

C. Culmsee, G. Melino, H. Zischka, 2017, Cell Death and Differentiation.

Mitochondrial dysfunction in oxidative stress

Barbara M. Bakker, Albert, Fabiana, 2017 .

Mitochondrial rescue prevents glutathione peroxidase‐dependent ferroptosis

C. Culmsee, R. Grosse, W. Diederich, 2018, Free radical biology & medicine.

Pifithrin-α provides neuroprotective effects at the level of mitochondria independently of p53 inhibition

C. Culmsee, G. Ganjam, S. Neitemeier, 2014, Apoptosis.

The serine protease inhibitor TLCK attenuates intrinsic death pathways in neurons upstream of mitochondrial demise

C. Culmsee, A. Dolga, G. Ganjam, 2014, Apoptosis.

Presenilin-1 Mutations Sensitize Neurons to DNA Damage-Induced Death by a Mechanism Involving Perturbed Calcium Homeostasis and Activation of Calpains and Caspase-12

W. Klapper, C. Culmsee, M. Mattson, 2002, Neurobiology of Disease.

[Pharmacotherapy of Parkinson's disease : Aspects of drug safety].

C. Culmsee, W. Oertel, C. Trenkwalder, 2017, Der Nervenarzt.

Sex differences in neonatal mouse brain injury after hypoxia‐ischemia and adaptaquin treatment

Changlian Zhu, C. Culmsee, Xiaoyang Wang, 2019, Journal of neurochemistry.

Chapter 6 SK channels differentially affect neurotoxicity in conditions of enhanced ER-mitochondrial coupling

C. Culmsee, A. Dolga, Martina Schmidt, 2017 .

The catalytic subunit of telomerase is expressed in developing brain neurons and serves a cell survival-promoting function

C. Culmsee, M. Mattson, T. Pandita, 2000, Journal of Molecular Neuroscience.

Ischaemic brain damage after stroke: new insights into efficient therapeutic strategies

C. Culmsee, J. Krieglstein, 2007, EMBO reports.

Small conductance Ca2+-activated K+ channels in the plasma membrane, mitochondria and the ER: Pharmacology and implications in neuronal diseases

C. Culmsee, A. Dolga, Inge E Krabbendam, 2017, Neurochemistry International.

Neuroprotection by Drug-Induced Neurotrophic Factors

C. Culmsee, J. Krieglstein, I. Semkova, 1997 .

SK channel activation is neuroprotective in conditions of enhanced ER–mitochondrial coupling

C. Culmsee, A. Dolga, J. Rieusset, 2018, Cell Death & Disease.

Glucose-regulated protein 75 determines ER–mitochondrial coupling and sensitivity to oxidative stress in neuronal cells

C. Culmsee, A. Dolga, J. Rieusset, 2017, Cell Death Discovery.

One protein, different cell fate: the differential outcome of depleting GRP75 during oxidative stress in neurons

C. Culmsee, A. Dolga, B. Honrath, 2018, Cell Death & Disease.

Parkin mediates neuroprotection through activation of IkappaB kinase/nuclear factor-kappaB signaling.

C. Culmsee, B. Berninger, D. Krappmann, 2007, The Journal of neuroscience : the official journal of the Society for Neuroscience.

BID links ferroptosis to mitochondrial cell death pathways

C. Culmsee, A. Dolga, S. Oppermann, 2017, Redox biology.

β2-Adrenoceptor stimulation enhances latent transforming growth factor-β-binding protein-1 and transforming growth factor-β1 expression in rat hippocampus after transient forebrain ischemia

C. Culmsee, J. Krieglstein, Y. Zhu, 2001, Neuroscience.

Clenbuterol induces growth factor mRNA, activates astrocytes, and protects rat brain tissue against ischemic damage.

C. Culmsee, J. Krieglstein, M. Schäfer, 1999, European journal of pharmacology.

Dynasore Blocks Ferroptosis through Combined Modulation of Iron Uptake and Inhibition of Mitochondrial Respiration

C. Culmsee, S. von Karstedt, Malena Rabenau, 2020, Cells.

Combination Therapy in Ischemic Stroke: Synergistic Neuroprotective Effects of Memantine and Clenbuterol

N. Plesnila, C. Culmsee, J. Krieglstein, 2004, Stroke.

Stimulation of β-adrenoceptors activates astrocytes and provides neuroprotection

C. Culmsee, J. Krieglstein, A. Becker, 2002 .

Tf-lipoplex-mediated c-Jun silencing improves neuronal survival following excitotoxic damage in vivo.

N. Plesnila, C. Culmsee, E. Wagner, 2010, Journal of controlled release : official journal of the Controlled Release Society.

Hippocampal neurons of mice deficient in DNA-dependent protein kinase exhibit increased vulnerability to DNA damage, oxidative stress and excitotoxicity.

C. Culmsee, M. Mattson, S. Bondada, 2001, Brain research. Molecular brain research.

IGF1R expression by adult oligodendrocytes is not required in the steady‐state but supports neuroinflammation

B. Becher, C. Culmsee, I. Bechmann, 2022, Glia.

Targeting beta2-adrenoceptors for neuroprotection after cerebral ischemia: is inhibition or stimulation best?

C. Culmsee, 2009, Anesthesia and analgesia.

Stimulation of β2-Adrenoceptors Induces Nerve Growth Factor and Inhibits Apoptosis in Rat Brain After Ischemia

C. Culmsee, J. Krieglstein, I. Semkova, 1999 .

Stimulation of beta-adrenoceptors activates astrocytes and provides neuroprotection.

C. Culmsee, J. Krieglstein, A. Becker, 2002, European journal of pharmacology.

Overexpression of suppressor of cytokine signaling 3 in the arcuate nucleus of juvenile Phodopus sungorus alters seasonal body weight changes

C. Culmsee, P. Barrett, A. Tups, 2013, Journal of Comparative Physiology B.

Stimulation of 5-HT1A receptors reduces apoptosis after transient forebrain ischemia in the rat

C. Culmsee, J. Krieglstein, M. Kouklei, 2000, Brain Research.

Stimulation of 5-HT receptors reduces apoptosis after transient 1 A forebrain ischemia in the rat *

C. Culmsee, J. Krieglstein, M. Kouklei, 2000 .

Stimulation of β2-Adrenoceptors Inhibits Apoptosis in Rat Brain after Transient Forebrain Ischemia

C. Culmsee, J. Krieglstein, I. Semkova, 1998 .

Novel p53 inactivators with neuroprotective action: syntheses and pharmacological evaluation of 2-imino-2,3,4,5,6,7-hexahydrobenzothiazole and 2-imino-2,3,4,5,6,7-hexahydrobenzoxazole derivatives.

C. Culmsee, M. Mattson, N. Greig, 2002, Journal of medicinal chemistry.

Synthesis and characterization of chemically condensed oligoethylenimine containing beta-aminopropionamide linkages for siRNA delivery.

C. Culmsee, E. Wagner, Katharina von Gersdorff, 2007, Biomaterials.

Apoptotic and antiapoptotic mechanisms in stroke

C. Culmsee, M. Mattson, Zaifang Yu, 2000, Cell and Tissue Research.

p53 in neuronal apoptosis.

C. Culmsee, M. Mattson, 2005, Biochemical and biophysical research communications.

Mitochondrial Ca2+-activated K+ channels and their role in cell life and death pathways.

C. Culmsee, A. Dolga, B. Honrath, 2018, Cell calcium.

Activation of SK2 channels preserves ER Ca2+ homeostasis and protects against ER stress-induced cell death

C. Culmsee, R. Dodel, A. Dolga, 2015, Cell Death and Differentiation.

Mitochondrial Small Conductance SK2 Channels Prevent Glutamate-induced Oxytosis and Mitochondrial Dysfunction*

N. Plesnila, C. Culmsee, H. Zischka, 2013, The Journal of Biological Chemistry.

Homocysteine Elicits a DNA Damage Response in Neurons That Promotes Apoptosis and Hypersensitivity to Excitotoxicity

C. Culmsee, M. Mattson, Zhihong Guo, 2000, The Journal of Neuroscience.

A Small-Molecule Inhibitor of Bax and Bak Oligomerization Prevents Genotoxic Cell Death and Promotes Neuroprotection.

D. Andrews, B. Leber, C. Culmsee, 2017, Cell chemical biology.

Activation of KCNN3/SK3/KCa2.3 channels attenuates enhanced calcium influx and inflammatory cytokine production in activated microglia

C. Culmsee, R. Dodel, A. Dolga, 2012, Glia.

The tyrosine phosphatase inhibitor orthovanadate mimics NGF-induced neuroprotective signaling in rat hippocampal neurons

C. Culmsee, J. Krieglstein, S. Klumpp, 2004, Neurochemistry International.

Exogenous Alpha-Synuclein Evoked Parkin Downregulation Promotes Mitochondrial Dysfunction in Neuronal Cells. Implications for Parkinson’s Disease Pathology

C. Culmsee, A. Adamczyk, H. Jęśko, 2021, Frontiers in Aging Neuroscience.

siRNA delivery by a transferrin‐associated lipid‐based vector: a non‐viral strategy to mediate gene silencing

C. Culmsee, E. Wagner, S. Simões, 2007, The journal of gene medicine.

Therapeutic targeting of oxygen-sensing prolyl hydroxylases abrogates ATF4-dependent neuronal death and improves outcomes after brain hemorrhage in several rodent models

Giovanni Coppola, Christopher J. Schofield, Sama F. Sleiman, 2016, Science Translational Medicine.

The metalloprotease-disintegrin ADAM8 contributes to temozolomide chemoresistance and enhanced invasiveness of human glioblastoma cells.

C. Culmsee, C. Nimsky, O. Schilling, 2015, Neuro-oncology.

Inhibition of the AIF/CypA complex protects against intrinsic death pathways induced by oxidative stress

N. Plesnila, C. Culmsee, A. Dolga, 2014, Cell Death and Disease.

Inhibition of Drp1 provides neuroprotection in vitro and in vivo

N. Plesnila, C. Culmsee, J. Nunnari, 2012, Cell Death and Differentiation.

Neurobiology of the major psychoses: a translational perspective on brain structure and function—the FOR2107 consortium

Tilo Kircher, Axel Krug, Tim Hahn, 2018, European Archives of Psychiatry and Clinical Neuroscience.

Inhibition of Carbonic Anhydrase 2 Overcomes Temozolomide Resistance in Glioblastoma Cells

C. Culmsee, C. Nimsky, A. Pagenstecher, 2021, International journal of molecular sciences.

Cofilin1-dependent actin dynamics control DRP1-mediated mitochondrial fission

C. Culmsee, L. Scorrano, W. Witke, 2017, Cell Death and Disease.

Bid mediates fission, membrane permeabilization and peri-nuclear accumulation of mitochondria as a prerequisite for oxidative neuronal cell death

N. Plesnila, C. Culmsee, J. Grohm, 2010, Brain, Behavior, and Immunity.

Nerve growth factor survival signaling in cultured hippocampal neurons is mediated through TrkA and requires the common neurotrophin receptor P75

C. Culmsee, M. Mattson, M. Nikolova-Karakashian, 2002, Neuroscience.

Pathogenesis of Ischemic Stroke

C. Culmsee, M. Mattson, 2001 .

Apoptosis-Inducing Factor Triggered by Poly(ADP-Ribose) Polymerase and Bid Mediates Neuronal Cell Death after Oxygen-Glucose Deprivation and Focal Cerebral Ischemia

N. Plesnila, Changlian Zhu, C. Culmsee, 2005, The Journal of Neuroscience.

Cylindromatosis mediates neuronal cell death in vitro and in vivo

N. Plesnila, C. Culmsee, J. Roth, 2018, Cell Death & Differentiation.

The β2-adrenoceptor agonist clenbuterol modulates Bcl-2, Bcl-xl and Bax protein expression following transient forebrain ischemia

C. Culmsee, J. Prehn, J. Krieglstein, 1999, Neuroscience.

Sex‐dependent effects of Cacna1c haploinsufficiency on juvenile social play behavior and pro‐social 50‐kHz ultrasonic communication in rats

M. Rietschel, C. Culmsee, R. Schwarting, 2020, Genes, brain, and behavior.

Transforming Growth Factor-β1 Increases Bad Phosphorylation and Protects Neurons Against Damage

C. Culmsee, Guo-Yuan Yang, B. Ahlemeyer, 2002, The Journal of Neuroscience.

Neuroprotection by transforming growth factor-β1 involves activation of nuclear factor-κB through phosphatidylinositol-3-OH kinase/Akt and mitogen-activated protein kinase-extracellular-signal regulated kinase1,2 signaling pathways

C. Culmsee, J. Krieglstein, Y. Zhu, 2004, Neuroscience.

Roles of Nuclear Factor κB in Neuronal Survival and Plasticity

C. Culmsee, M. Mattson, Zaifang Yu, 2000 .

Targeting Bid to prevent programmed cell death in neurons.

N. Plesnila, C. Culmsee, 2006, Biochemical Society transactions.

Structure–activity relationships by interligand NOE-based design and synthesis of antiapoptotic compounds targeting Bid

Maurizio Pellecchia, Marilisa Leone, John C Reed, 2006, Proceedings of the National Academy of Sciences.

Bid-induced release of AIF from mitochondria causes immediate neuronal cell death

N. Plesnila, C. Culmsee, S. Duvezin-Caubet, 2008, Cell Death and Differentiation.

Delayed neuronal death after brain trauma involves p53-dependent inhibition of NF-κB transcriptional activity

N. Plesnila, C. Culmsee, E. Wagner, 2007, Cell Death and Differentiation.

Reciprocal Inhibition of p53 and Nuclear Factor-κB Transcriptional Activities Determines Cell Survival or Death in Neurons

C. Culmsee, M. Mattson, J. Krieglstein, 2003, The Journal of Neuroscience.

SK2 channels regulate mitochondrial respiration and mitochondrial Ca2+ uptake

C. Culmsee, H. Zischka, F. Perocchi, 2016, Cell Death and Differentiation.

Novel N-Phenyl–Substituted Thiazolidinediones Protect Neural Cells against Glutamate- and tBid-Induced Toxicity

C. Culmsee, M. Schlitzer, A. Dolga, 2014, The Journal of Pharmacology and Experimental Therapeutics.

Treat more than heat-New therapeutic implications of Cimicifuga racemosa through AMPK-dependent metabolic effects.

C. Culmsee, J. Drewe, Georg Boonen, 2022, Phytomedicine : international journal of phytotherapy and phytopharmacology.

Neuroprotection by Estrogens in a Mouse Model of Focal Cerebral Ischemia and in Cultured Neurons: Evidence for a Receptor-Independent Antioxidative Mechanism

C. Culmsee, B. Ahlemeyer, J. Krieglstein, 1999, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Trifluoperazine rescues human dopaminergic cells from wild-type α-synuclein-induced toxicity

C. Culmsee, W. Oertel, A. Dolga, 2014, Neurobiology of Aging.

Neuronal apoptosis in Alzheimer ’ s disease

C. Culmsee, M. Mattson, W. Duan, 2001 .

The Potential Role of Ferroptosis in Neonatal Brain Injury

Changlian Zhu, C. Culmsee, Xiaoyang Wang, 2019, Front. Neurosci..

Molecular Mechanisms Underlying Oxytosis

C. Culmsee, A. Dolga, S. Oppermann, 2018, Apoptosis and Beyond.

SK-Channel Activation Alters Peripheral Metabolic Pathways in Mice, but Not Lipopolysaccharide-Induced Fever or Inflammation

C. Culmsee, A. Dolga, J. Roth, 2022, Journal of inflammation research.

Induction of activating transcription factor 3 by anoxia is independent of p53 and the hypoxic HIF signalling pathway

C. Culmsee, A. Harris, Tsonwin Hai, 2007, Oncogene.

A synthetic inhibitor of p53 protects neurons against death induced by ischemic and excitotoxic insults, and amyloid β‐peptide

C. Culmsee, M. Mattson, N. Greig, 2001 .

Mitochondria, Microglia, and the Immune System—How Are They Linked in Affective Disorders?

C. Culmsee, V. Arolt, U. Dannlowski, 2019, Front. Psychiatry.

Free Fatty Acids in Bone Pathophysiology of Rheumatic Diseases

C. Culmsee, U. Müller-Ladner, M. Zaiss, 2019, Front. Immunol..

Cytochrome c Oxidase Inhibition by ATP Decreases Mitochondrial ROS Production

C. Culmsee, A. Dolga, P. Weber, 2022, Cells.

Guidelines on experimental methods to assess mitochondrial dysfunction in cellular models of neurodegenerative diseases

David S. Park, S. Lipton, C. Culmsee, 2017, Cell Death & Differentiation.

A Dual Role for the SDF-1/CXCR4 Chemokine Receptor System in Adult Brain: Isoform-Selective Regulation of SDF-1 Expression Modulates CXCR4-Dependent Neuronal Plasticity and Cerebral Leukocyte Recruitment after Focal Ischemia

C. Culmsee, S. Schulz, J. Krieglstein, 2002, The Journal of Neuroscience.

Design, Optimization, and Structural Characterization of an Apoptosis-Inducing Factor Peptide Targeting Human Cyclophilin A to Inhibit Apoptosis Inducing Factor-Mediated Cell Death.

C. Culmsee, A. Dolga, L. Russo, 2021, Journal of medicinal chemistry.

Causal role of apoptosis-inducing factor for neuronal cell death following traumatic brain injury.

N. Plesnila, Changlian Zhu, C. Culmsee, 2008, The American journal of pathology.

Involvement of Apoptosis-Inducing Factor (AIF) in Neuronal Cell Death Following Cerebral Ischemia

N. Plesnila, C. Culmsee, 2018 .

AIF depletion provides neuroprotection through a preconditioning effect

C. Culmsee, A. Dolga, Eva-Maria Öxler, 2012, Apoptosis.

Significant Role of Apoptosis-Inducing Factor (AIF) for Brain Damage Following Focal Cerebral Ischemia

N. Plesnila, C. Culmsee, 2010 .

Apoptosis-inducing factor is a major contributor to neuronal loss induced by neonatal cerebral hypoxia-ischemia

N. Plesnila, C. Culmsee, K. Blomgren, 2007, Cell Death and Differentiation.

The expression of transforming growth factor-beta1 (TGF-β1) in hippocampal neurons: a temporary upregulated protein level after transient forebrain ischemia in the rat

C. Culmsee, J. Krieglstein, A. Rami, 2000, Brain Research.

Targeting of polyplexes: toward synthetic virus vector systems.

C. Culmsee, Sabine Boeckle, E. Wagner, 2005, Advances in genetics.

Cellular and Molecular Mechanisms Underlying Synaptic Degeneration and Neuronal Death in Alzheimer’s Disease

C. Culmsee, M. Mattson, W. A. Pedersen, 2001 .

Psychiatric risk gene Cacna1c determines mitochondrial resilience against oxidative stress in neurons

C. Culmsee, R. Schwarting, M. Wöhr, 2018, Cell Death & Disease.

Cacna1c haploinsufficiency leads to pro-social 50-kHz ultrasonic communication deficits in rats

M. Rietschel, C. Culmsee, R. Schwarting, 2018, Disease Models & Mechanisms.

Bid-mediated mitochondrial damage is a key mechanism in glutamate-induced oxidative stress and AIF-dependent cell death in immortalized HT-22 hippocampal neurons

N. Plesnila, C. Culmsee, M. Conrad, 2011, Cell Death and Differentiation.

Mitochondrial damage by α-synuclein causes cell death in human dopaminergic neurons

C. Culmsee, W. Oertel, A. Dolga, 2019, Cell Death & Disease.

AMP-activated protein kinase is highly expressed in neurons in the developing rat brain and promotes neuronal survival following glucose deprivation

C. Culmsee, M. Mattson, B. Kemp, 2001, Journal of Molecular Neuroscience.

RIPK1 or RIPK3 deletion prevents progressive neuronal cell death and improves memory function after traumatic brain injury

N. Plesnila, C. Culmsee, P. Vandenabeele, 2021, Acta Neuropathologica Communications.

α1-antitrypsin modulates microglial-mediated neuroinflammation and protects microglial cells from amyloid-β-induced toxicity

C. Culmsee, A. Koczulla, R. Dodel, 2014, Journal of Neuroinflammation.

A new approach on assessing clinical pharmacists’ impact on prescribing errors in a surgical intensive care unit

C. Culmsee, M. Hoeckel, M. Tryba, 2019, International Journal of Clinical Pharmacy.

Upregulation of the Enzyme Chain Hydrolyzing Extracellular ATP after Transient Forebrain Ischemia in the Rat

C. Culmsee, J. Krieglstein, H. Zimmermann, 1998, The Journal of Neuroscience.

p75 neurotrophin receptor is required for constitutive and NGF‐induced survival signalling in PC12 cells and rat hippocampal neurones

C. Culmsee, J. Prehn, J. Krieglstein, 2002, Journal of neurochemistry.

The VAMP-associated protein VAPB is required for cardiac and neuronal pacemaker channel function

C. Culmsee, T. Budde, L. Monassier, 2018, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Cofilin1 oxidation links oxidative distress to mitochondrial demise and neuronal cell death

C. Culmsee, E. Hanschmann, M. Rust, 2020, Cell Death & Disease.

Medication Review by Community Pharmacists for Type 2 Diabetes Patients in Routine Care: Results of the DIATHEM-Study

C. Culmsee, C. Hohmann, Elisabeth Schindler, 2020, Frontiers in Pharmacology.

Adaptive Plasticity in Tachykinin and Tachykinin Receptor Expression after Focal Cerebral Ischemia Is Differentially Linked to GABAergic and Glutamatergic Cerebrocortical Circuits and Cerebrovenular Endothelium

C. Culmsee, J. Krieglstein, M. Schäfer, 2001, The Journal of Neuroscience.

Molecular insights into mechanisms of the cell death program: role in the progression of neurodegenerative disorders.

C. Culmsee, S. Landshamer, 2006, Current Alzheimer research.

Evidence for the Involvement of Par-4 in Ischemic Neuron Cell Death

C. Culmsee, M. Mattson, J. Krieglstein, 2001, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Lithium protects hippocampal progenitors, cognitive performance and hypothalamus–pituitary function after irradiation to the juvenile rat brain

Changlian Zhu, C. Culmsee, K. Blomgren, 2017, Oncotarget.

Antiproliferative effects of cimicifuga racemosa root extract Ze 450 mediated by inhibition of oxidative phosphorylation and indirect AMPK activation

C. Culmsee, J. Drewe, V. Butterweck, 2019, Maturitas.

Nitric Oxide Donors Induce Neurotrophin-Like Survival Signaling and Protect Neurons against Apoptosis

C. Culmsee, K. Umezawa, J. Krieglstein, 2005, Molecular Pharmacology.

Dying transplanted neural stem cells mediate survival bystander effects in the injured brain

N. Plesnila, Changlian Zhu, C. Culmsee, 2023, Cell Death & Disease.

Tf-lipoplexes for neuronal siRNA delivery: a promising system to mediate gene silencing in the CNS.

N. Plesnila, C. Culmsee, E. Wagner, 2008, Journal of controlled release : official journal of the Controlled Release Society.

Cimicifuga racemosa Extract Ze 450 Re-Balances Energy Metabolism and Promotes Longevity

C. Culmsee, J. Drewe, V. Butterweck, 2021, Antioxidants.

The neuroprotective role of microglial cells against amyloid beta‐mediated toxicity in organotypic hippocampal slice cultures

C. Culmsee, R. Dodel, A. Dolga, 2019, Brain pathology.

SK channel-mediated metabolic escape to glycolysis inhibits ferroptosis and supports stress resistance in C. elegans

Barbara M. Bakker, C. Culmsee, R. Branicky, 2020, Cell Death & Disease.

Central Application of Aliskiren, a Renin Inhibitor, Improves Outcome After Experimental Stroke Independent of Its Blood Pressure Lowering Effect

N. Plesnila, C. Culmsee, N. Terpolilli, 2019, Front. Neurol..

Protective Roles for Potassium SK/KCa2 Channels in Microglia and Neurons

C. Culmsee, A. Dolga, 2012, Front. Pharmacol..

Bone marrow stromal cells mediate protection through stimulation of PI3-K/Akt and MAPK signaling in neurons

N. Plesnila, C. Culmsee, A. Straube, 2007, Neurochemistry International.

Subcellular expression and neuroprotective effects of SK channels in human dopaminergic neurons

N. Plesnila, C. Culmsee, H. Zischka, 2014, Cell Death and Disease.

KCa2 channels activation prevents [Ca2+]i deregulation and reduces neuronal death following glutamate toxicity and cerebral ischemia

N. Plesnila, C. Culmsee, A. Dolga, 2011, Cell Death and Disease.

Current concepts in chronic inflammatory diseases: Interactions between microbes, cellular metabolism, and inflammation.

C. Culmsee, K. Preissner, H. Bisgaard, 2016, The Journal of allergy and clinical immunology.

Roles of nuclear factor kappaB in neuronal survival and plasticity.

C. Culmsee, M. Mattson, S. Camandola, 2000, Journal of neurochemistry.

Cylindromatosis mediates neuronal cell death in vitro and in vivo

N. Plesnila, C. Culmsee, J. Roth, 2018, Cell Death & Differentiation.

SK channel activation potentiates auranofin-induced cell death in glio- and neuroblastoma cells.

C. Culmsee, A. Dolga, F. Kruyt, 2019, Biochemical pharmacology.

Targeting the p53 pathway to protect the neonatal ischemic brain

C. Culmsee, H. Hagberg, M. A. van der Kooij, 2011, Annals of neurology.

Drug Safety Analysis in a Real-Life Cohort of Parkinson’s Disease Patients with Polypharmacy

C. Culmsee, W. Oertel, C. Trenkwalder, 2017, CNS Drugs.

The beta2-adrenoceptor agonist clenbuterol modulates Bcl-2, Bcl-xl and Bax protein expression following transient forebrain ischemia.

C. Culmsee, J. Prehn, J. Krieglstein, 1999, Neuroscience.

Pifithrin-α provides neuroprotective effects at the level of mitochondria independently of p53 inhibition

C. Culmsee, G. Ganjam, S. Neitemeier, 2014, Apoptosis.

Characterization of Novel Diphenylamine Compounds as Ferroptosis Inhibitors

C. Culmsee, M. Schlitzer, L. Hinder, 2021, The Journal of Pharmacology and Experimental Therapeutics.

SK channel activation modulates mitochondrial respiration and attenuates neuronal HT-22 cell damage induced by H2O2

C. Culmsee, R. Dodel, A. Dolga, 2015, Neurochemistry International.

Beta(2)-adrenoceptor stimulation enhances latent transforming growth factor-beta-binding protein-1 and transforming growth factor-beta1 expression in rat hippocampus after transient forebrain ischemia.

C. Culmsee, J. Krieglstein, Y. Zhu, 2001, Neuroscience.

University of Groningen Protective Roles for Potassium SK / K ( Ca ) 2 Channels in Microglia and Neurons

C. Culmsee, A. Dolga, 2012 .

and reduces neuronal death following glutamate toxicity and cerebral ischemia

N. Plesnila, C. Culmsee, N. Terpolilli, 2011 .

]i deregulation and reduces neuronal death following glutamate toxicity and cerebral ischemia

N. Plesnila, C. Culmsee, A. Dolga, 2011 .

Mechanisms of neuronal degeneration after ischemic stroke – Emerging targets for novel therapeutic strategies

C. Culmsee, J. Krieglstein, 2005 .

Mitochondrial Reactive Oxygen Species Formation Determines ACSL4/LPCAT2-Mediated Ferroptosis

C. Culmsee, D. Steinhilber, Moritz Boll, 2023, Antioxidants.

Interaction between BID and VDAC1 is required for mitochondrial demise and cell death in neurons

N. Plesnila, C. Culmsee, A. Dolga, 2021, bioRxiv.

The serine protease inhibitor TLCK attenuates intrinsic death pathways in neurons upstream of mitochondrial demise

C. Culmsee, A. Dolga, G. Ganjam, 2014, Apoptosis.

Impedance measurement for real time detection of neuronal cell death

C. Culmsee, A. Dolga, S. Diemert, 2012, Journal of Neuroscience Methods.

Cyclase-associated protein 2 (CAP2) controls MRTF-A localization and SRF activity in mouse embryonic fibroblasts

C. Culmsee, E. Marcello, M. Ruscica, 2020, Scientific Reports.

Clinical relevance of potential self-medication drug interactions in antineoplastic and immune-modulating therapy among online pharmacy customers

C. Culmsee, N. Harbeck, T. Kolben, 2023, Therapeutic advances in drug safety.

Effects of Cimicifuga racemosa extract Ze450 on mitochondria in models of oxidative stress in neuronal cells

C. Culmsee, J. Drewe, M. Unger, 2018, Data in brief.

Pathogenesis of Ischemic Stroke

C. Culmsee, M. Mattson, 2001 .

n-3 Polyunsaturated Fatty Acids Modulate LPS-Induced ARDS and the Lung–Brain Axis of Communication in Wild-Type versus Fat-1 Mice Genetically Modified for Leukotriene B4 Receptor 1 or Chemerin Receptor 23 Knockout

C. Culmsee, J. Kang, J. Bier, 2023, International journal of molecular sciences.

NGF mediates the neuroprotective effect of the β 2-adrenoceptor agonist clenbuterol in vitro and in vivo: evidence from an NGF-antisense study

C. Culmsee, J. Krieglstein, I. Semkova, 1999, Neurochemistry International.