B. Cullen

发表

A highly conserved RNA folding region coincident with the Rev response element of primate immunodeficiency viruses.

S. Le, J. Maizel, M. Malim, 1990, Nucleic acids research.

The HIV-1 rev trans-activator acts through a structured target sequence to activate nuclear export of unspliced viral mRNA

S. Le, J. Maizel, M. Malim, 1989, Nature.

Characterization of Staphylococcus aureus Cas9: a smaller Cas9 for all-in-one adeno-associated virus delivery and paired nickase applications

Morgan L. Maeder, B. Cullen, Ari E. Friedland, 2015, Genome Biology.

The role of RNAi and microRNAs in animal virus replication and antiviral immunity.

B. Cullen, J. L. Umbach, Bryan R Cullen, 2009, Genes & development.

Viral and cellular microRNAs as determinants of viral pathogenesis and immunity.

B. Cullen, E. Gottwein, Eva Gottwein, 2008, Cell host & microbe.

Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs.

B. Cullen, R. Yi, I. Macara, 2003, Genes & development.

Human microRNAs are processed from capped, polyadenylated transcripts that can also function as mRNAs.

B. Cullen, C. Hagedorn, Xuezhong Cai, 2004, RNA.

Structural requirements for pre-microRNA binding and nuclear export by Exportin 5.

B. Cullen, Yan Zeng, Yan Zeng, 2004, Nucleic acids research.

Overexpression of exportin 5 enhances RNA interference mediated by short hairpin RNAs and microRNAs.

B. Cullen, R. Yi, I. Macara, 2005, RNA.

Utilization of a mammalian cell-based RNA binding assay to characterize the RNA binding properties of picornavirus 3C proteinases.

B. Cullen, B. Semler, W. Blair, 1998, RNA.

The human endogenous retrovirus K Rev response element coincides with a predicted RNA folding region.

S. Le, B. Cullen, H. Bogerd, 2000, RNA.

Enhancing and confirming the specificity of RNAi experiments

B. Cullen, 2006, Nature Methods.

Viruses and microRNAs

B. Cullen, 2006, Nature Genetics.

Transcription and processing of human microRNA precursors.

B. Cullen, 2004, Molecular cell.

Sequence requirements for micro RNA processing and function in human cells.

B. Cullen, Yan Zeng, Bryan R Cullen, 2003, RNA.

The imprinted H19 noncoding RNA is a primary microRNA precursor.

B. Cullen, Xuezhong Cai, Bryan R Cullen, 2007, RNA.

siRNAs: a new wave of RNA-based therapeutics.

B. Cullen, Bryan R Cullen, G. A. Coburn, 2003, The Journal of antimicrobial chemotherapy.

Kaposi's sarcoma-associated herpesvirus expresses an array of viral microRNAs in latently infected cells.

Blossom Damania, B. Cullen, Zhihong Zhang, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Epstein–Barr Virus MicroRNAs Are Evolutionarily Conserved and Differentially Expressed

Alexandra Schäfer, B. Cullen, R. Desrosiers, 2006, PLoS pathogens.

Regulation of human immunodeficiency virus replication.

B. Cullen, 1991, Annual review of microbiology.

In-Depth Analysis of the Interaction of HIV-1 with Cellular microRNA Biogenesis and Effector Mechanisms

B. Cullen, O. Flores, M. Stevenson, 2013, mBio.

Reversal of Epigenetic Silencing Allows Robust HIV-1 Replication in the Absence of Integrase Function

B. Cullen, K. Tsai, H. Bogerd, 2020, mBio.

Robust HIV-1 replication in the absence of integrase function

B. Cullen, K. Tsai, H. Bogerd, 2020, bioRxiv.

Epitranscriptomic Addition of m5C to HIV-1 Transcripts Regulates Viral Gene Expression.

Edward M Kennedy, B. Cullen, R. Swanstrom, 2019, Cell host & microbe.

Partial reconstitution of the RNAi response in human cells using Drosophila gene products

B. Cullen, E. Kennedy, Anand V. R. Kornepati, 2017, RNA.

Identification of the envelope V3 loop as the primary determinant of cell tropism in HIV-1.

B. Cullen, H. Lyerly, S. Hwang, 1991, Science.

Recognition and cleavage of primary microRNA precursors by the nuclear processing enzyme Drosha

B. Cullen, R. Yi, Yan Zeng, 2005, The EMBO journal.

Analysis of the Interaction of Primate Retroviruses with the Human RNA Interference Machinery

Bryan R. Cullen, B. Cullen, Jennifer W. Lin, 2007, Journal of Virology.

In-Depth Analysis of Kaposi's Sarcoma-Associated Herpesvirus MicroRNA Expression Provides Insights into the Mammalian MicroRNA-Processing Machinery

Bryan R. Cullen, B. Cullen, J. L. Umbach, 2009, Journal of Virology.

Virally Induced Cellular MicroRNA miR-155 Plays a Key Role in B-Cell Immortalization by Epstein-Barr Virus

Bryan R. Cullen, Sarah D. Linnstaedt, B. Cullen, 2010, Journal of Virology.

Viruses, microRNAs, and host interactions.

B. Cullen, Rebecca L Skalsky, Bryan R Cullen, 2010, Annual review of microbiology.

Role of chemokine receptors in HIV-1 infection and pathogenesis.

B. Cullen, P. Bieniasz, T. Ross, 1999, Advances in virus research.

Posttranscriptional m(6)A Editing of HIV-1 mRNAs Enhances Viral Gene Expression.

Bryan R. Cullen, Edward M. Kennedy, B. Cullen, 2016, Cell host & microbe.

Posttranscriptional m6A Editing of HIV-1 mRNAs Enhances Viral Gene Expression.

B. Cullen, E. Kennedy, Anand V. R. Kornepati, 2017, Cell host & microbe.

The Control of Human Retrovirus Gene Expression

B. Franza, B. Cullen, F. Wong-Staal, 1988 .

Recognition and cleavage of primary microRNA transcripts.

B. Cullen, Yan Zeng, Bryan R Cullen, 2006, Methods in molecular biology.

MicroRNAs and small interfering RNAs can inhibit mRNA expression by similar mechanisms

B. Cullen, R. Yi, Yan Zeng, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Functional replacement of the HIV-1 rev protein by the HTLV-1 rex protein

M. Malim, B. Cullen, J. Hauber, 1988, Nature.

HIV‐1‐induced cell fusion is mediated by multiple regions within both the viral envelope and the CCR‐5 co‐receptor

B. Cullen, M. Caron, P. Bieniasz, 1997, The EMBO journal.

Identification of regions in HIV-1 Nef required for efficient downregulation of cell surface CD4.

B. Cullen, R. Truant, W. Blair, 1997, Virology.

Probing RNA conformational equilibria within the functional cellular context

Laura R. Ganser, B. Cullen, H. Al‐Hashimi, 2019, bioRxiv.

The ability of HIV type 1 to use CCR-3 as a coreceptor is controlled by envelope V1/V2 sequences acting in conjunction with a CCR-5 tropic V3 loop.

B. Cullen, T. Ross, Bryan R. Cullen, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Molecular mechanism of desensitization of the chemokine receptor CCR‐5: receptor signaling and internalization are dissociable from its role as an HIV‐1 co‐receptor

B. Cullen, M. Caron, P. Bieniasz, 1997, The EMBO journal.

Cloning and analysis of microRNAs encoded by the primate gamma-herpesvirus rhesus monkey rhadinovirus.

B. Cullen, R. Desrosiers, A. Schäfer, 2007, Virology.

Adenomatous polyposis coli protein contains two nuclear export signals and shuttles between the nucleus and cytoplasm.

B. Cullen, M. Beckerle, D. Nix, 2000, Proceedings of the National Academy of Sciences of the United States of America.

In vivo hypermutation of xenotropic murine leukemia virus-related virus DNA in peripheral blood mononuclear cells of rhesus macaque by APOBEC3 proteins.

B. Cullen, R. Silverman, E. Klein, 2011, Virology.

Nuclear RNA export

B. Cullen, Bryan R Cullen, 2003, Journal of Cell Science.

Human immunodeficiency virus: Nuclear RNA export unwound

B. Cullen, 2005, Nature.

Exon junction complexes mediate the enhancing effect of splicing on mRNA expression

B. Cullen, Shihua Lu, H. Wiegand, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Trans-activation of human immunodeficiency virus occurs via a bimodal mechanism

Bryan R. Cullen, B. Cullen, 1986, Cell.

Revealing the high propensity of RNAs to non-specifically bind drug-like small molecules

Laura R. Ganser, B. Cullen, H. Al‐Hashimi, 2020, bioRxiv.

Virus Type 1 Transcriptional Activator of Simian Foamy Consensus DNA Binding Sequence for the Tas Derivation and Functional Characterization of a

B. Cullen, Yibin Kang, 1998 .

Derivation and Functional Characterization of a Consensus DNA Binding Sequence for the Tas Transcriptional Activator of Simian Foamy Virus Type 1

B. Cullen, Yibin Kang, 1998, Journal of Virology.

Human immunodeficiency virus types 1 and 2 and simian immunodeficiency virus Nef use distinct but overlapping target sites for downregulation of cell surface CD4

B. Cullen, J. Hua, Jian Hua, 1997, Journal of virology.

Murine CXCR-4 is a functional coreceptor for T-cell-tropic and dual-tropic strains of human immunodeficiency virus type 1

B. Cullen, P. Bieniasz, R. Fridell, 1997, Journal of virology.

A single stem-loop structure within the HTLV-1 Rex response element is sufficient to mediate Rex activity in vivo.

B. Cullen, E. Hoffmann, S. Berchtold, 1994, Virology.

Mutational analysis of the transcription activation domain of RelA: identification of a highly synergistic minimal acidic activation module

B. Cullen, S. Madore, W. Blair, 1994, Molecular and cellular biology.

Rev activates expression of the human immunodeficiency virus type 1 vif and vpr gene products

B. Cullen, L. Tiley, E. Garrett, 1991, Journal of virology.

Nef protein of human immunodeficiency virus type 1: evidence against its role as a transcriptional inhibitor.

M. Malim, B. Cullen, W. Greene, 1989, Proceedings of the National Academy of Sciences of the United States of America.

Expression of a cloned human interleukin-2 cDNA is enhanced by the substitution of a heterologous mRNA leader region.

B. Cullen, 1988, DNA.

Subcellular localization of the human immunodeficiency virus trans-acting art gene product

B. Cullen, J. Hauber, J. Sodroski, 1988, Journal of virology.

Endogenous avian retroviruses contain deficient promoter and leader sequences.

B. Cullen, A. Skalka, G. Ju, 1983, Proceedings of the National Academy of Sciences of the United States of America.

Functional domain organization of human APOBEC3G.

B. Cullen, B. Gooch, 2008, Virology.

The Human Tap Nuclear RNA Export Factor Contains a Novel Transportin-dependent Nuclear Localization Signal That Lacks Nuclear Export Signal Function*

B. Cullen, R. Truant, Y. Kang, 1999, The Journal of Biological Chemistry.

Expression of CRISPR/Cas single guide RNAs using small tRNA promoters

B. Cullen, E. Kennedy, Anand V. R. Kornepati, 2015, RNA.

Does RNA interference have a future as a treatment for HIV-1 induced disease?

B. Cullen, 2005, AIDS reviews.

Making a NeST for a persistent virus.

B. Cullen, 2013, Cell host & microbe.

Definition of a Consensus Transportin-specific Nucleocytoplasmic Transport Signal*

B. Cullen, R. Truant, H. Bogerd, 1999, The Journal of Biological Chemistry.

Identification and Functional Characterization of a High-Affinity Bel-1 DNA Binding Site Located in the Human Foamy Virus Internal Promoter

B. Cullen, Yibin Kang, W. Blair, 1998, Journal of Virology.

Characterization of human interferon-gamma and human interleukin-2 from recombinant mammalian cell lines and peripheral blood lymphocytes.

B. Cullen, R. Chizzonite, F. Riske, 1991, Lymphokine and cytokine research.

Expression of active, membrane-bound human placental alkaline phosphatase by transfected simian cells.

B. Cullen, S. Udenfriend, L. Gerber, 1987, Proceedings of the National Academy of Sciences of the United States of America.

Tax Induces the Recruitment of NF-κB to Unintegrated HIV-1 DNA To Rescue Viral Gene Expression and Replication

B. Cullen, I. Irwan, 2021, bioRxiv.

Tax Induces the Recruitment of NF-κB to Unintegrated HIV-1 DNA To Rescue Viral Gene Expression and Replication

B. Cullen, I. Irwan, 2021, Journal of virology.

Analysis of the RNA binding specificity of the human tap protein, a constitutive transport element-specific nuclear RNA export factor.

B. Cullen, Yibin Kang, H. Bogerd, 1999, Virology.

Nonsense Mediated Decay Induced by Tethered Human UPF3B is Restricted to the Cytoplasm

B. Cullen, Shihua Lu, 2004, RNA biology.

Connections between the processing and nuclear export of mRNA: evidence for an export license?

B. Cullen, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Five Questions about Viruses and MicroRNAs

B. Cullen, 2010, PLoS pathogens.

A lentiviral vector bearing a reverse intron demonstrates superior expression of both proteins and microRNAs

B. Cullen, E. Kennedy, K. Tsai, 2017, RNA biology.

The Members of an Epstein-Barr Virus MicroRNA Cluster Cooperate To Transform B Lymphocytes

B. Cullen, R. Feederle, S. Linnstaedt, 2011, Journal of Virology.

Structural and functional analysis of the avian leukemia virus

B. Cullen, Jin Yang, 1999 .

Chaperoning a pathogen

J. Heitman, B. Cullen, 1994, Nature.

Identiﬁcation and Functional Characterization of a Novel Nuclear Localization Signal Present in the Yeast Nab2 Poly(A) 1 RNA Binding Protein

B. Cullen, R. Truant, H. Bogerd, 1998 .

A Cluster of Virus-Encoded MicroRNAs Accelerates Acute Systemic Epstein-Barr Virus Infection but Does Not Significantly Enhance Virus-Induced Oncogenesis In Vivo

B. Cullen, J. Garcia, S. Linnstaedt, 2013, Journal of Virology.

HIV-1 Vif: counteracting innate antiretroviral defenses.

B. Cullen, 2003, Molecular therapy : the journal of the American Society of Gene Therapy.

Rev and the fate of pre-mRNA in the nucleus: implications for the regulation of RNA processing in eukaryotes

M. Malim, B. Cullen, Andbryan R. Cullen, 1993, Molecular and cellular biology.

Requirement of the human T-cell leukemia virus (HTLV-1) tax-stimulated HIAP-1 gene for the survival of transformed lymphocytes.

B. Cullen, R. Grassmann, Grit Schneider, 2006, Blood.

Molecular mechanism of desensitization of the chemokine receptor CCR5 : receptor signaling and internalization are dissociable from its role as an HIV-1 co-receptor important in acute inflammatory responses

B. Cullen, M. Caron, P. Bieniasz, 2013 .

Molecular Basis for Cell Tropism of CXCR4-Dependent Human Immunodeficiency Virus Type 1 Isolates

B. Cullen, H. Lyerly, M. Morse, 2001, Journal of Virology.

A competitive enzyme-linked immunoassay (ELISA) for the measurement of soluble human interleukin-2 receptors (IL-2R, Tac protein).

B. Cullen, A. Goldstein, D. Nelson, 1988, Journal of immunological methods.

Mechanisms of control of gene expression

B. Cullen, H. Weissbach, A. Skalka, 1987 .

Influenza A virus-derived siRNAs increase in the absence of NS1 yet fail to inhibit virus replication

B. Cullen, K. Tsai, D. Courtney, 2018, RNA.

RNA-sequence-mediated gene regulation in HIV-1.

B. Cullen, 1994, Infectious agents and disease.

Sequence requirements for Rev multimerization in vivo.

M. Malim, B. Cullen, S. Madore, 1994, Virology.

Epitranscriptomic addition of m 6 A regulates HIV-1 RNA stability and alternative splicing

B. Cullen, R. Swanstrom, K. Tsai, 2021 .

The Bel-1 protein of human foamy virus activates human immunodeficiency virus type 1 gene expression via a novel DNA target site

B. Cullen, E. Garrett, A. Keller, 1992, Journal of virology.

Cyclophilin B escorts the hepatitis C virus RNA polymerase: a viral achilles heel?

J. Heitman, B. Cullen, 2005, Molecular cell.

The virology–RNA biology connection

B. Cullen, 2015, RNA.

A rapid and simple procedure for the preparation of homogeneously labeled DNA probes.

B. Cullen, 1986, Gene.

Expression of transfected DNA in avian cells can be enhanced in trans by retroviral infection

B. Cullen, R. Katz, G. Ju, 1985, Molecular and cellular biology.

Functional Analysis of the Transcription Control Region Located Within the Avian Retroviral Long Terminal Repeat

B. Cullen, G. Ju, K. Raymond, 1985, Molecular and cellular biology.

Functional analysis of the transcription control region located within the avian retroviral long terminal repeat

B. Cullen, G. Ju, K. Raymond, 1985 .

Identification of HIV-1 variants capable of entering T cells via the CD8 receptor suggests a new mode of viral pathogenesis. But are these variants rare, aberrant viruses or a real problem? (pages 65-72)

B. Cullen, 2001 .

A new entry route for HIV

B. Cullen, 2001, Nature Medicine.

RoleoftheAvianRetrovirus mRNA Leader inExpression: Evidence forNovelTranslational Control

B. Cullen, 1986 .

Identification and Functional Characterization of a High-Affinity Bel-1 DNA Binding Site Located in the Human Foamy Virus Internal Promoter

B. Cullen, Yibin Kang, W. Blair, 1998, Journal of Virology.

Epigenetic silencing by the SMC5/6 complex mediates HIV-1 latency

B. Cullen, H. Bogerd, I. Irwan, 2022, Nature Microbiology.

Persistently adenovirus-infected lymphoid cells express microRNAs derived from the viral VAI and especially VAII RNA.

B. Cullen, Y. Furuse, D. Ornelles, 2013, Virology.

Bromodeoxyuridine induction of deoxycytidine deaminase activity in a hamster cell line.

B. Cullen, M. Bick, 1978, Biochimica et biophysica acta.

APOBEC3A and APOBEC3B are potent inhibitors of LTR-retrotransposon function in human cells

B. Cullen, B. Doehle, H. Bogerd, 2006, Nucleic acids research.

Equine Infectious Anemia Virus Resists the Antiretroviral Activity of Equine APOBEC3 Proteins through a Packaging-Independent Mechanism

B. Cullen, S. Carpenter, H. Bogerd, 2008, Journal of Virology.

Single-stranded RNA facilitates nucleocapsid: APOBEC3G complex formation.

B. Cullen, H. Bogerd, 2008, RNA.

The Betaretrovirus Mason-Pﬁzer Monkey Virus Selectively Excludes Simian APOBEC3G from Virion Particles (cid:1)

B. Cullen, P. Bieniasz, E. Hunter, 2006 .

Differential Sensitivity of Murine Leukemia Virus to APOBEC3-Mediated Inhibition Is Governed by Virion Exclusion

B. Cullen, A. Schäfer, B. Doehle, 2005, Journal of Virology.

Bromodeoxyuridine inhibition of Friend leukemia cell induction by butyric acid: Time course of inhibition, reversal, and effect of other base analogs

B. Cullen, M. Bick, 1976 .

MicroRNA Target Site Identification by Integrating Sequence and Binding Information

Bryan R. Cullen, Uwe Ohler, William H. Majoros, 2013, Nature Methods.

Multiple Residues Contribute to the Inability of Murine CCR-5 To Function as a Coreceptor for Macrophage-Tropic Human Immunodeficiency Virus Type 1 Isolates

Bryan R. Cullen, B. Cullen, P. Bieniasz, 1998, Journal of Virology.

Understanding the characteristics of nonspecific binding of drug-like compounds to canonical stem–loop RNAs and their implications for functional cellular assays

Laura R. Ganser, B. Cullen, H. Al‐Hashimi, 2020, RNA.

Transcriptional activity of avian retroviral long terminal repeats directly correlates with enhancer activity

B. Cullen, G. Ju, K. Raymond, 1985, Journal of virology.

Viral sequences determining the oncogenicity of avian leukosis viruses.

B. Cullen, A. Skalka, P. Tsichlis, 1983, Progress in clinical and biological research.

Both natural and designed micro RNAs can inhibit the expression of cognate mRNAs when expressed in human cells.

Eric J Wagner, B. Cullen, E. Wagner, 2002, Molecular cell.

The role of avian retroviral LTRs in the regulation of gene expression and viral replication.

B. Cullen, G. Ju, 1985, Advances in virus research.

Use of eukaryotic expression technology in the functional analysis of cloned genes.

B. Cullen, 1987, Methods in enzymology.

Transcriptional interference in avian retroviruses—implications for the promoter insertion model of leukaemogenesis

B. Cullen, P. Lomedico, G. Ju, 1984, Nature.

Derivation and function of small interfering RNAs and microRNAs.

B. Cullen, 2004, Virus research.

Multiple Blocks to Human Immunodeficiency Virus Type 1 Replication in Rodent Cells

B. Cullen, P. Bieniasz, 2000, Journal of Virology.

Structural and functional analysis of the avian leukemia virus constitutive transport element.

B. Cullen, J. Yang, Jin Yang, 1999, RNA.

Identification of a novel human zinc finger protein that specifically interacts with the activation domain of lentiviral Tat proteins.

B. Cullen, H. Bogerd, R. Fridell, 1995, Virology.

Potent and Specific Inhibition of Human Immunodeficiency Virus Type 1 Replication by RNA Interference

B. Cullen, G. A. Coburn, 2002, Journal of Virology.

Molecular basis of latency in pathogenic human viruses.

B. Cullen, M. Garcia-Blanco, 1991, Science.

MicroRNAs expressed by herpes simplex virus 1 during latent infection regulate viral mRNAs

B. Cullen, D. Coen, I. Jurak, 2008, Nature.

Journey to the Center of the Cell

B. Cullen, 2001, Cell.

Novel interleukin-2 receptor subunit detected by cross-linking under high-affinity conditions.

B. Cullen, R. Klausner, W. Leonard, 1986, Science.

Bacterial CRISPR/Cas DNA endonucleases: A revolutionary technology that could dramatically impact viral research and treatment.

B. Cullen, E. M. Kennedy, 2015, Virology.

Inactivation of the Human Papillomavirus E6 or E7 Gene in Cervical Carcinoma Cells by Using a Bacterial CRISPR/Cas RNA-Guided Endonuclease

Bryan R. Cullen, Edward M. Kennedy, B. Cullen, 2014, Journal of Virology.

A viral microRNA functions as an orthologue of cellular miR-155

Bryan R. Cullen, Uwe Ohler, William H. Majoros, 2007, Nature.

Analysis of the mRNA Targetome of MicroRNAs Expressed by Marek’s Disease Virus

D. Corcoran, B. Cullen, Oren Parnas, 2014, mBio.

Structural and functional analysis of the visna virus Rev-response element

B. Cullen, L. Tiley, 1992, Journal of virology.

Visna virus encodes a post-transcriptional regulator of viral structural gene expression.

S Y Le, J V Maizel, S. Le, 1990, Proceedings of the National Academy of Sciences of the United States of America.

Erratum: Visna virus encodes a post-transcriptional regulator of viral structural gene expression (Proc. Natl. Acad. Sci. USA (October 1990) 87 (7497-7501))

Bryan R. Cullen, Jacob V. Maizel, J. Maizel, 1990 .

Functional analysis of interactions between Tat and the trans-activation response element of human immunodeficiency virus type 1 in cells

B. Cullen, B. Peterlin, S. Madore, 1993, Journal of virology.

Mechanism of action of regulatory proteins encoded by complex retroviruses

B. Cullen, Bryan R. Cullen, 1992, Microbiological reviews.

Trans-activation of human immunodeficiency virus gene expression is mediated by nuclear events.

B. Cullen, J. Hauber, A. Perkins, 1987, Proceedings of the National Academy of Sciences of the United States of America.

Human immunodeficiency virus as a prototypic complex retrovirus

B. Cullen, B R Cullen, Bryan R. Cullen, 1991, Journal of virology.

Functions of the auxiliary gene products of the human immunodeficiency virus type 1.

B. Cullen, W. Greene, 1990, Virology.

Regulatory pathways governing HIV-1 replication

B. Cullen, W. Greene, 1989, Cell.

Secreted placental alkaline phosphatase as a eukaryotic reporter gene.

M. Malim, B. Cullen, B. R. Cullen, 1992, Methods in enzymology.

Viral and cellular messenger RNA targets of viral microRNAs

Bryan R. Cullen, B. Cullen, 2009, Nature.

COOH-terminal requirements for the correct processing of a phosphatidylinositol-glycan anchored membrane protein.

B. Cullen, J. Hauber, S. Udenfriend, 1988, The Journal of biological chemistry.

Secreted placental alkaline phosphatase: a powerful new quantitative indicator of gene expression in eukaryotic cells.

B. Cullen, J. Hauber, R. Geiger, 1988, Gene.

Downregulation of cell-surface CD4 expression by simian immunodeficiency virus Nef prevents viral super infection

B. Cullen, J. Ottinger, C. Doyle, 1993, The Journal of experimental medicine.

Comparative analysis of the HTLV-I Rex and HIV-1 Rev trans-regulatory proteins and their RNA response elements.

W C Greene, S Y Le, J V Maizel, 1989, Genes & development.

Functional dissection of the HIV-1 Rev trans-activator—Derivation of a trans-dominant repressor of Rev function

M. Malim, B. Cullen, J. Hauber, 1989, Cell.

Identification of Viral MicroRNAs Expressed in Human Sacral Ganglia Latently Infected with Herpes Simplex Virus 2

B. Cullen, J. Cohen, J. L. Umbach, 2009, Journal of Virology.

Analysis of Human Alphaherpesvirus MicroRNA Expression in Latently Infected Human Trigeminal Ganglia

B. Cullen, R. Cohrs, D. Gilden, 2009, Journal of Virology.

Epitranscriptomic Addition of m 5C to HIV-1 Transcripts Regulates Viral Gene Expression

B. Cullen, R. Swanstrom, K. Tsai, 2019, SSRN Electronic Journal.

Role and Mechanism of Action of the APOBEC3 Family of Antiretroviral Resistance Factors

B. Cullen, 2006, Journal of Virology.

Specific packaging of APOBEC3G into HIV-1 virions is mediated by the nucleocapsid domain of the gag polyprotein precursor.

B. Cullen, A. Schäfer, H. Bogerd, 2004, Virology.

A second human antiretroviral factor, APOBEC3F, is suppressed by the HIV‐1 and HIV‐2 Vif proteins

B. Cullen, B. Doehle, H. Bogerd, 2004, The EMBO journal.

Suppression of hepatitis B virus DNA accumulation in chronically infected cells using a bacterial CRISPR/Cas RNA-guided DNA endonuclease.

B. Cullen, R. Schinazi, H. Bogerd, 2015, Virology.

RNA interference: antiviral defense and genetic tool

Bryan R. Cullen, B. Cullen, 2002, Nature Immunology.

Inhibition of HIV-1 progeny virion release by cell-surface CD4 is relieved by expression of the viral Nef protein

B. Cullen, T. Ross, A. Oran, 1999, Current Biology.

HIV-1 Auxiliary Proteins: Making Connections in a Dying Cell

B. Cullen, 1998, Cell.

Stable expression of transdominant Rev protein in human T cells inhibits human immunodeficiency virus replication

M. Malim, B. Cullen, G. Nabel, 1992, The Journal of experimental medicine.

Characterization of the transcriptional trans activator of human foamy retrovirus

B. Cullen, M. Löchelt, R. Flügel, 1991, Journal of virology.

Targeting hepatitis B virus cccDNA using CRISPR/Cas9.

B. Cullen, E. M. Kennedy, A. Kornepati, 2015, Antiviral research.

Adenovirus VA1 Noncoding RNA Can Inhibit Small Interfering RNA and MicroRNA Biogenesis

B. Cullen, Shihua Lu, 2004, Journal of Virology.

The Viral and Cellular MicroRNA Targetome in Lymphoblastoid Cell Lines

Bryan R. Cullen, Uwe Ohler, Thomas Tuschl, 2012, PLoS pathogens.

A mammalian herpesvirus uses noncanonical expression and processing mechanisms to generate viral MicroRNAs.

B. Cullen, Xuezhong Cai, H. Bogerd, 2010, Molecular cell.

Effect of RNA secondary structure on polyadenylation site selection.

B. Cullen, B R Cullen, P H Brown, 1991, Genes & development.

Epitranscriptomic addition of m6A regulates HIV-1 RNA stability and alternative splicing

B. Cullen, R. Swanstrom, K. Tsai, 2021, bioRxiv.

Protocols for expression and functional analysis of viral microRNAs.

B. Cullen, E. Gottwein, 2007, Methods in enzymology.

The Biogenesis and Function of MicroRNAs

B. Cullen, Yan Zeng, Yan Zeng, 2006 .

Intrinsic Immunity

B. Cullen, 2013, Current Topics in Microbiology and Immunology.

A neuron-specific host microRNA targets herpes simplex virus-1 ICP0 expression and promotes latency.

B. Cullen, D. Coen, O. Flores, 2014, Cell host & microbe.

How Do Viruses Avoid Inhibition by Endogenous Cellular MicroRNAs?

B. Cullen, 2013, PLoS pathogens.

A Novel Assay for Viral MicroRNA Function Identifies a Single Nucleotide Polymorphism That Affects Drosha Processing

B. Cullen, E. Gottwein, Xuezhong Cai, 2006, Journal of Virology.

Replication of Many Human Viruses Is Refractory to Inhibition by Endogenous Cellular MicroRNAs

B. Cullen, M. Garcia-Blanco, D. Griffin, 2014, Journal of Virology.

Cellular MicroRNAs Refractory to Inhibition by Endogenous Replication of Many Human Viruses Is

B. Cullen, M. Garcia-Blanco, P. Bogerd, 2014 .

Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health,

B. Cullen, M. Garcia-Blanco, D. Griffin, 2014 .

Is RNA interference involved in intrinsic antiviral immunity in mammals?

B. Cullen, 2006, Nature Immunology.

Search for MicroRNAs Expressed by Intracellular Bacterial Pathogens in Infected Mammalian Cells

B. Cullen, R. Valdivia, H. A. Saka, 2014, PloS one.

Induction of stable RNA interference in mammalian cells

B. Cullen, 2006, Gene Therapy.

Efficient Processing of Primary microRNA Hairpins by Drosha Requires Flanking Nonstructured RNA Sequences*

B. Cullen, Yan Zeng, Yan Zeng, 2005, Journal of Biological Chemistry.

Stable inhibition of hepatitis B virus proteins by small interfering RNA expressed from viral vectors

B. Cullen, R. Russell, M. D. Moore, 2005, The journal of gene medicine.

RNA interference in human cells is restricted to the cytoplasm.

B. Cullen, Yan Zeng, Yan Zeng, 2002, RNA.

Mutational Inactivation of Herpes Simplex Virus 1 MicroRNAs Identifies Viral mRNA Targets and Reveals Phenotypic Effects in Culture

B. Cullen, O. Flores, D. Bloom, 2013, Journal of Virology.

Analysis of rhesus rhadinovirus microRNAs expressed in virus-induced tumors from infected rhesus macaques.

B. Cullen, J. L. Umbach, L. Strelow, 2010, Virology.

Human Papillomavirus Genotype 31 Does Not Express Detectable MicroRNA Levels during Latent or Productive Virus Replication

B. Cullen, Xuezhong Cai, Gu Li, 2006, Journal of Virology.

Expression and function of microRNAs encoded by Kaposi's sarcoma-associated herpesvirus.

B. Cullen, E. Gottwein, X. Cai, 2006, Cold Spring Harbor symposia on quantitative biology.

RNAi the natural way

B. Cullen, Bryan R Cullen, 2005, Nature Genetics.

Use of RNA polymerase II to transcribe artificial microRNAs.

B. Cullen, Yan Zeng, Xuezhong Cai, 2005, Methods in enzymology.

Synergistic enhancement of both initiation and elongation by acidic transcription activation domains.

B. Cullen, R. Fridell, W. S. Blair, 1996, The EMBO journal.

The Epstein-Barr virus miR-BHRF1 microRNAs regulate viral gene expression in cis.

B. Cullen, M. Luftig, Alexander M. Price, 2017, Virology.

The Epstein-Barr Virus miR-BHRF1 microRNAs Regulate Viral Gene Expression in cis

B. Cullen, M. Luftig, Alexander M. Price, 2017, bioRxiv.

Derivation and characterization of Dicer- and microRNA-deficient human cells

B. Cullen, O. Flores, H. Bogerd, 2014, RNA.

A Human Herpesvirus MicroRNA Inhibits p21 Expression and Attenuates p21-Mediated Cell Cycle Arrest

B. Cullen, E. Gottwein, 2010, Journal of Virology.

Reduced Expression of Brain-Enriched microRNAs in Glioblastomas Permits Targeted Regulation of a Cell Death Gene

Bryan R. Cullen, B. Cullen, Rebecca L. Skalsky, 2011, PloS one.

Viral microRNA targetome of KSHV-infected primary effusion lymphoma cell lines.

Uwe Ohler, Neelanjan Mukherjee, Thomas Tuschl, 2011, Cell host & microbe.

Viruses and microRNAs: RISCy interactions with serious consequences.

B. Cullen, Bryan R Cullen, 2011, Genes & development.

MicroRNA Antagonism of the Picornaviral Life Cycle: Alternative Mechanisms of Interference

B. Cullen, S. Russell, E. Hadac, 2010, PLoS pathogens.

A Viral microRNA Cluster Strongly Potentiates the Transforming Properties of a Human Herpesvirus

B. Cullen, R. Feederle, S. Linnstaedt, 2011, PLoS pathogens.

Herpesvirus microRNAs: phenotypes and functions.

B. Cullen, 2011, Current opinion in virology.

Nuclear export of late HIV-1 mRNAs occurs via a cellular protein export pathway.

B. Cullen, H. Bogerd, R. Fridell, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Amphibian transcription factor IIIA proteins contain a sequence element functionally equivalent to the nuclear export signal of human immunodeficiency virus type 1 Rev.

M. Malim, B. Cullen, R. Lührmann, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Identification of a novel cellular cofactor for the Rev/Rex class of retroviral regulatory proteins

B. Cullen, S. Madore, H. Bogerd, 1995, Cell.

Selective inhibition of Alu retrotransposition by APOBEC3G.

J. V. Moran, B. Cullen, H. Bogerd, 2007, Gene.

Cellular inhibitors of long interspersed element 1 and Alu retrotransposition.

J. V. Moran, B. Cullen, H. Bogerd, 2006, Proceedings of the National Academy of Sciences of the United States of America.

Inhibition of Human Immunodeficiency Virus Rev and Human T-Cell Leukemia Virus Rex Function, but Not Mason-Pfizer Monkey Virus Constitutive Transport Element Activity, by a Mutant Human Nucleoporin Targeted to Crm1

B. Cullen, T. Ross, A. Echarri, 1998, Journal of Virology.

Protein sequence requirements for function of the human T-cell leukemia virus type 1 Rex nuclear export signal delineated by a novel in vivo randomization-selection assay

B. Cullen, H. Bogerd, R. Fridell, 1996, Molecular and cellular biology.

Insights into the mechanisms underlying the inactivation of HIV-1 proviruses by CRISPR/Cas.

B. Cullen, H. Bogerd, I. Irwan, 2018, Virology.

Specific induction of endogenous viral restriction factors using CRISPR/Cas-derived transcriptional activators

Edward M Kennedy, B. Cullen, H. Bogerd, 2015, Proceedings of the National Academy of Sciences.

Identification of microRNAs expressed in two mosquito vectors, Aedes albopictus and Culex quinquefasciatus

B. Cullen, S. Higgs, D. Vanlandingham, 2010, BMC Genomics.

MicroRNA‐17∼92 plays a causative role in lymphomagenesis by coordinating multiple oncogenic pathways

B. Cullen, K. Rajewsky, C. Xiao, 2013, The EMBO journal.

Genetic analysis indicates that the human foamy virus Bel-1 protein contains a transcription activation domain of the acidic class

B. Cullen, W. Blair, H. Bogerd, 1994, Journal of Virology.

Transcriptional trans activators of human and simian foamy viruses contain a small, highly conserved activation domain

B. Cullen, H. Bogerd, F. He, 1993, Journal of virology.

Genetic evidence that the Tat proteins of human immunodeficiency virus types 1 and 2 can multimerize in the eukaryotic cell nucleus

B. Cullen, W. Blair, H. Bogerd, 1993, Journal of virology.

Functional organization of the Bel-1 trans activator of human foamy virus

B. Cullen, F. He, J. D. Sun, 1993, Journal of virology.

The VP16 transcription activation domain is functional when targeted to a promoter-proximal RNA sequence.

M. Malim, B. Cullen, S. Madore, 1992, Genes & development.

Analysis of the stimulatory effect of splicing on mRNA production and utilization in mammalian cells.

B. Cullen, Shihua Lu, 2003, RNA.

Recruitment of cyclin T1/P-TEFb to an HIV type 1 long terminal repeat promoter proximal RNA target is both necessary and sufficient for full activation of transcription.

B. Cullen, P. Bieniasz, H. Bogerd, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Non-coding Regulatory RNAs of the DNA Tumor Viruses

B. Cullen, C. S. Sullivan, 2009 .

Structure-function analyses of the HTLV-I Rex and HIV-1 Rev RNA response elements: insights into the mechanism of Rex and Rev action.

M. Malim, B. Cullen, W. Greene, 1990, Genes & development.

HIV-1 structural gene expression requires binding of the rev trans-activator to its RNA target sequence

Bryan R. Cullen, Michael H. Malim, Joachim Hauber, 1990, Cell.

The Arginine-Rich Domains Present in Human Immunodeficiency Virus Type 1 Tat and Rev Function as Direct Importin β-Dependent Nuclear Localization Signals

Bryan R. Cullen, B. Cullen, R. Truant, 1999, Molecular and Cellular Biology.

Identification and Functional Characterization of a Novel Nuclear Localization Signal Present in the Yeast Nab2 Poly(A)+ RNA Binding Protein

B. Cullen, R. Truant, H. Bogerd, 1998, Molecular and Cellular Biology.

RNA Interference in Mammals: The Virus Strikes Back.

B. Cullen, 2017, Immunity.

Mutational definition of the human immunodeficiency virus type 1 Rev activation domain

M. Malim, B. Cullen, L. Tiley, 1991, Journal of virology.

Inhibition of Human Immunodeficiency Virus Type 1 Replication in Primary Macrophages by Using Tat- or CCR5-Specific Small Interfering RNAs Expressed from a Lentivirus Vector

B. Cullen, M. Mcclure, G. A. Coburn, 2003, Journal of Virology.

Productive human immunodeficiency virus type 1 (HIV-1) infection of nonproliferating human monocytes

M. Malim, B. Cullen, T. Matthews, 1991, The Journal of experimental medicine.

Nuclear mRNA export: insights from virology.

B. Cullen, Bryan R Cullen, 2003, Trends in biochemical sciences.

Effects of chimeric mutants of human immunodeficiency virus type 1 Rev and human T-cell leukemia virus type I Rex on nucleolar targeting signals

B. Cullen, M. Maki, S. Kubota, 1991, Journal of virology.

Role of the avian retrovirus mRNA leader in expression: evidence for novel translational control

B. Cullen, A. Skalka, R. Katz, 1986, Molecular and cellular biology.

HIV-1 Nef protein: An invitation to a kill

Bryan R. Cullen, B. Cullen, 1999, Nature Medicine.

Production of functional small interfering RNAs by an amino-terminal deletion mutant of human Dicer

B. Cullen, H. Bogerd, Adam W. Whisnant, 2015, Proceedings of the National Academy of Sciences.

Is RNA interference a physiologically relevant innate antiviral immune response in mammals?

B. Cullen, S. Cherry, B. tenOever, 2013, Cell host & microbe.

Transcriptional Origin of Kaposi's Sarcoma-Associated Herpesvirus MicroRNAs

B. Cullen, Xuezhong Cai, 2006, Journal of Virology.

by RNA Interference Immunodeficiency Virus Type 1 Replication Potent and Specific Inhibition of Human

B. Cullen, G. A. Coburn, 2002 .

Rapid analysis of small nucleic acid samples by gel electrophoresis.

B. Cullen, D. Stacey, J. Kopchick, 1981, Analytical biochemistry.

Viruses and RNA Interference: Issues and Controversies

B. Cullen, 2014, Journal of Virology.

Controversies Viruses and RNA Interference : Issues and

B. Cullen, 2014 .

Identification of a U5-specific sequence required for efficient polyadenylation within the human immunodeficiency virus long terminal repeat

B. Cullen, J. Hauber, S. Böhnlein, 1989, Journal of virology.

Formation of Tap/NXT1 Heterodimers Activates Tap-Dependent Nuclear mRNA Export by Enhancing Recruitment to Nuclear Pore Complexes

B. Cullen, Yibin Kang, Yan Zeng, 2002, Molecular and Cellular Biology.

A second human interleukin-2 binding protein that may be a component of high-affinity interleukin-2 receptors

B. Cullen, W. Greene, L. Thuy, 1987, Nature.

In vitro selection of DNA elements highly responsive to the human T-cell lymphotropic virus type I transcriptional activator, Tax

B. Cullen, I. Boros, J. Cross, 1994, Molecular and cellular biology.

MicroRNAs as mediators of viral evasion of the immune system

B. Cullen, 2013, Nature Immunology.

Epitranscriptomic Enhancement of Influenza A Virus Gene Expression and Replication.

Edward M Kennedy, B. Cullen, N. Heaton, 2017, Cell host & microbe.

Extensive Epitranscriptomic Methylation of A and C Residues on Murine Leukemia Virus Transcripts Enhances Viral Gene Expression

B. Cullen, H. Bogerd, D. Courtney, 2019, mBio.

Human APOBEC3 proteins can inhibit xenotropic murine leukemia virus-related virus infectivity.

B. Cullen, P. Bieniasz, H. Bogerd, 2011, Virology.

Effect of intron size on splicing efficiency in retroviral transcripts.

B. Cullen, D. Stacey, J. Kopchick, 1982, Nucleic acids research.

APC‐mediated downregulation of β‐catenin activity involves nuclear sequestration and nuclear export

Raymond L. White, B. Cullen, K. Neufeld, 2000, EMBO reports.

Regulation of the human c-myc gene: 5' noncoding sequences do not affect translation

B. Cullen, A. Skalka, C. Miyamoto, 1985, Molecular and cellular biology.

Inhibition of Alpharetrovirus Replication by a Range of Human APOBEC3 Proteins

B. Cullen, H. Wiegand, Heather L. Wiegand, 2007, Journal of Virology.

Foamy Virus Bet Proteins Function as Novel Inhibitors of the APOBEC3 Family of Innate Antiretroviral Defense Factors

B. Cullen, A. Schäfer, R. Russell, 2005, Journal of Virology.

Efficient polyadenylation within the human immunodeficiency virus type 1 long terminal repeat requires flanking U3-specific sequences

B. Cullen, B R Cullen, P H Brown, 1991, Journal of virology.

Genetic analysis of the cofactor requirement for human immunodeficiency virus type 1 Tat function

B. Cullen, S. Madore, Bryan R. Cullen, 1993, Journal of virology.

Recruitment of a protein complex containing Tat and cyclin T1 to TAR governs the species specificity of HIV‐1 Tat

B. Cullen, P. Bieniasz, H. Bogerd, 1998, The EMBO journal.

IMMUNODEFICIENCY VIRUS REPLICATION

B. Cullen, 1991 .

Immunodeficiency virus rev trans-activator modulates the expression of the viral regulatory genes

M. Malim, B. Cullen, J. Hauber, 1988, Nature.

Identification of Novel, Highly Expressed Retroviral MicroRNAs in Cells Infected by Bovine Foamy Virus

B. Cullen, M. Löchelt, Adam W. Whisnant, 2014, Journal of Virology.

Regulation of HIV‐1 gene expression

B. Cullen, Bryan R. Cullen, 1991, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

HIV-1 structural gene expression requires the binding of multiple Rev monomers to the viral RRE: Implications for HIV-1 latency

M. Malim, B. Cullen, 1991, Cell.

Regulation of gene expression in the human immunodeficiency virus type 1.

B. Cullen, 1991, Advances in virus research.

Functional Differences between Human and Bovine Immunodeficiency Virus Tat Transcription Factors

B. Cullen, P. Bieniasz, H. Bogerd, 2000, Journal of Virology.

Highly Divergent Lentiviral Tat Proteins Activate Viral Gene Expression by a Common Mechanism

B. Cullen, P. Bieniasz, H. Bogerd, 1999, Molecular and Cellular Biology.

Analysis of the Effect of Natural Sequence Variation in Tat and in Cyclin T on the Formation and RNA Binding Properties of Tat-Cyclin T Complexes

B. Cullen, P. Bieniasz, H. Bogerd, 1999, Journal of Virology.

Regulation of HIV gene expression.

B. Cullen, 1995, AIDS.

EBV Noncoding RNAs.

B. Cullen, Rebecca L. Skalsky, 2015, Current topics in microbiology and immunology.

Human APOBEC3B is a potent inhibitor of HIV-1 infectivity and is resistant to HIV-1 Vif.

B. Cullen, A. Schäfer, B. Doehle, 2005, Virology.

Probing RNA conformational equilibria within the functional cellular context

Laura R. Ganser, B. Cullen, H. Al‐Hashimi, 2019, bioRxiv.

Viral RNAs: Lessons from the Enemy

B. Cullen, 2009, Cell.

Human topoisomerase I promotes HIV-1 proviral DNA synthesis: Implications for the species specificity and cellular tropism of HIV-1 infection

B. Cullen, Y. Shoya, Hidehiro Takahashi, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Species and Tissue Tropisms of HIV-1 : Molecular Basis and Phenotypic Consequences

B. Cullen, 2001 .

Principles and applications of a Tat-based assay for analyzing specific RNA-protein interactions in mammalian cells.

B. Cullen, 2000, Methods in enzymology.

Does HIV-1 Tat induce a change in viral initiation rights?

B. Cullen, 1993, Cell.

Functional characterization of a complex protein-DNA-binding domain located within the human immunodeficiency virus type 1 long terminal repeat leader region

M. Malim, B. Cullen, J. Hauber, 1989, Journal of virology.

Does the human immunodeficiency virus Tat trans-activator contain a discrete activation domain?

B. Cullen, L. Tiley, P. H. Brown, 1990, Virology.

The intrinsic antiretroviral factor APOBEC3B contains two enzymatically active cytidine deaminase domains.

B. Cullen, B. Doehle, H. Bogerd, 2007, Virology.

MicroRNAs as Mediators of Viral Immune Evasion

B. Cullen, 2013 .

Inhibition of a Yeast LTR Retrotransposon by Human APOBEC3 Cytidine Deaminases

B. Cullen, A. Schäfer, M. Curcio, 2005, Current Biology.

Epigenetic and epitranscriptomic regulation of viral replication

B. Cullen, K. Tsai, 2020, Nature Reviews Microbiology.

B. Cullen, S. Madore, 1995, Virology.

Analysis of viral microRNA expression by elephant endotheliotropic herpesvirus 1.

B. Cullen, Y. Furuse, F. Steinbach, 2014, Virology.

Lymphocryptovirus MicroRNA Targets Evolutionary Conservation of Primate

B. Cullen, S. Linnstaedt, Dong Kang, 2014 .

Evolutionary Conservation of Primate Lymphocryptovirus MicroRNA Targets

B. Cullen, S. Linnstaedt, Dong Kang, 2013, Journal of Virology.

Specific binding of the human T-cell leukemia virus type I Rex protein to a short RNA sequence located within the Rex-response element

B. Cullen, H. Bogerd, L. Tiley, 1992, Journal of virology.

Identification of a high-affinity RNA-binding site for the human immunodeficiency virus type 1 Rev protein

M. Malim, B. Cullen, P. Stockley, 1992, Proceedings of the National Academy of Sciences of the United States of America.

The human foamy virus Bel-1 transcription factor is a sequence-specific DNA binding protein

B. Cullen, J. Fukushima, W. Blair, 1996, Journal of virology.

A single amino acid difference in the host APOBEC3G protein controls the primate species specificity of HIV type 1 virion infectivity factor.

B. Cullen, B. Doehle, H. Bogerd, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Human immunodeficiency virus type 1 rev protein as a negative trans-regulator.

B. Cullen, F. Wong-Staal, M. Sadaie, 1989, DNA.

A yeast TATA-binding protein mutant that selectively enhances gene expression from weak RNA polymerase II promoters

B. Cullen, W. Blair, B R Cullen, 1997, Molecular and cellular biology.

Identification of envelope V3 loop as the major determinant of CD4 neutralization sensitivity of HIV-1.

B. Cullen, H. Lyerly, S. Hwang, 1992, Science.

Targeting HPV16 DNA using CRISPR/Cas inhibits anal cancer growth in vivo

B. Cullen, D. Hsu, E. M. Kennedy, 2018, Future virology.

Gene Editing: A New Tool for Viral Disease.

B. Cullen, E. M. Kennedy, 2017, Annual review of medicine.

Optimization of a multiplex CRISPR/Cas system for use as an antiviral therapeutic.

B. Cullen, K. Tsai, H. Bogerd, 2015, Methods.

EBV BART MicroRNAs Target Multiple Pro-apoptotic Cellular Genes to Promote Epithelial Cell Survival

B. Cullen, Dong Kang, Rebecca L. Skalsky, 2015, PLoS pathogens.

Functional comparison of the Rev trans-activators encoded by different primate immunodeficiency virus species.

S. Le, J. Maizel, M. Malim, 1989, Proceedings of the National Academy of Sciences of the United States of America.

Mapping RNA Modifications Using Photo-Crosslinking-Assisted Modification Sequencing.

B. Cullen, K. Tsai, 2021, Methods in molecular biology.

Mutational analysis of the conserved basic domain of human immunodeficiency virus tat protein

M. Malim, B. Cullen, J. Hauber, 1989, Journal of virology.

Mutational analysis of the trans-activation-responsive region of the human immunodeficiency virus type I long terminal repeat

B. Cullen, J. Hauber, 1988, Journal of virology.

The HIV-1 Tat protein: An RNA sequence-specific processivity factor?

B. Cullen, 1990, Cell.

A comparison of regulatory features in primate lentiviruses.

B. Cullen, E. Garrett, 1992, AIDS research and human retroviruses.

Influenza A Virus Expresses High Levels of an Unusual Class of Small Viral Leader RNAs in Infected Cells

B. Cullen, H. Yen, L. Poon, 2010, mBio.

Epitranscriptomic Regulation of HIV-1 Gene Expression by m 5C and the Novel m 5C Reader MBD2

B. Cullen, R. Swanstrom, K. Tsai, 2019, SSRN Electronic Journal.

Chemokine receptors and human immunodeficiency virus infection.

B. Cullen, P. Bieniasz, Bryan R. Cullen, 1998, Frontiers in bioscience : a journal and virtual library.

The human Tap protein is a nuclear mRNA export factor that contains novel RNA-binding and nucleocytoplasmic transport sequences.

B. Cullen, Yibin Kang, Y. Kang, 1999, Genes & development.

The HIV-1 Rev protein: prototype of a novel class of eukaryotic post-transcriptional regulators.

M. Malim, B. Cullen, 1991, Trends in biochemical sciences.

Analysis of Cellular Factors That Mediate Nuclear Export of RNAs Bearing the Mason-Pfizer Monkey Virus Constitutive Transport Element

B. Cullen, Yibin Kang, H. Bogerd, 2000, Journal of Virology.

Nuclear RNA Export Pathways

B. Cullen, 2000, Molecular and Cellular Biology.

HIV-1 infection: fooling the gatekeeper

B. Cullen, 2003, Nature Medicine.

Using retroviruses to study the nuclear export of mRNA.

B. Cullen, 2002, Results and problems in cell differentiation.

Nuclear import of hnRNP A1 is mediated by a novel cellular cofactor related to karyopherin-beta.

B. Cullen, R. Truant, L. Thorne, 1997, Journal of cell science.

A nuclear role for the Fragile X mental retardation protein.

B. Cullen, H. Bogerd, R. Fridell, 1996, The EMBO journal.

Viral Epitranscriptomics

B. Cullen, K. Tsai, D. Courtney, 2017, Journal of Virology.

D. Page, B. Cullen, H. Bogerd, 2001, Molecular cell.

Using viral species specificity to define a critical protein/RNA interaction surface.

B. Cullen, M. Georgiadis, Y. Kang, 2001, Genes & development.

Retroviruses as model systems for the study of nuclear RNA export pathways.

B. Cullen, 1998, Virology.

The R Region Found in the Human Foamy Virus Long Terminal Repeat Is Critical for both Gag and Pol Protein Expression

B. Cullen, R. Russell, M. Mcclure, 2001, Journal of Virology.

Mutational Definition of Functional Domains within the Rev Homolog Encoded by Human Endogenous Retrovirus K

B. Cullen, H. Bogerd, Jin Yang, 2000, Journal of Virology.

Nucleocytoplasmic shuttling by protein nuclear import factors.

B. Cullen, R. Truant, R. Fridell, 1998, European journal of cell biology.

Determination of the Functional Domain Organization of the Importin α Nuclear Import Factor

Bryan R. Cullen, B. Cullen, R. Truant, 1998, The Journal of cell biology.

Nuclear import of hnRNP A 1 is mediated by a novel cellular cofactor related to karyopherin-β

B. Cullen, R. Truant, L. Thorne, 1997 .

Mapping of pseudouridine residues on cellular and viral transcripts using a novel antibody-based technique

B. Cullen, K. Tsai, H. Bogerd, 2021, bioRxiv.

The crystal structure and mutational analysis of a novel RNA-binding domain found in the human Tap nuclear mRNA export factor

Dona N. Ho, B. Cullen, Yibin Kang, 2002, Proceedings of the National Academy of Sciences of the United States of America.

The SMC5/6 complex: An emerging antiviral restriction factor that can silence episomal DNA

B. Cullen, I. Irwan, 2023, PLoS pathogens.

The role of Nef in the replication cycle of the human and simian immunodeficiency viruses.

B. Cullen, 1994, Virology.

Differential RISC association of endogenous human microRNAs predicts their inhibitory potential

B. Cullen, O. Flores, Rebecca L. Skalsky, 2014, Nucleic acids research.

Recruitment of the Crm1 Nuclear Export Factor Is Sufficient To Induce Cytoplasmic Expression of Incompletely Spliced Human Immunodeficiency Virus mRNAs

Bryan R. Cullen, B. Cullen, R. Yi, 2002, Journal of Virology.

Both ran and importins have the ability to function as nuclear mRNA export factors.

B. Cullen, R. Yi, H. Bogerd, 2002, RNA.

Induced Packaging of Cellular MicroRNAs into HIV-1 Virions Can Inhibit Infectivity

B. Cullen, H. Bogerd, Adam W. Whisnant, 2017, mBio.

The Betaretrovirus Mason-Pfizer Monkey Virus Selectively Excludes Simian APOBEC3G from Virion Particles

B. Cullen, P. Bieniasz, E. Hunter, 2006, Journal of Virology.

Assaying nuclear messenger RNA export in human cells.

B. Cullen, 2004, Methods in molecular biology.

Genetic Evidence that theTatProteins ofHuman Immunodeficiency Virus Types1and2CanMultimerize intheEukaryotic CellNucleus

B. Cullen, W. Blair, H. Bogerd, 1993 .

An ancient family of human endogenous retroviruses encodes a functional homolog of the HIV-1 Rev protein.

B. Cullen, R. Truant, S. Peng, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Addition of m6A to SV40 late mRNAs enhances viral structural gene expression and replication

B. Cullen, K. Tsai, D. Courtney, 2018, PLoS pathogens.

Derivation of a biologically contained replication system for human immunodeficiency virus type 1.

M. Malim, B. Cullen, H. Lyerly, 1992, Proceedings of the National Academy of Sciences of the United States of America.

The simian immunodeficiency virus Nef protein promotes degradation of CD4 in human T cells.

B. Cullen, C. Doyle, A. Sanfridson, 1994, The Journal of biological chemistry.

Acetylation of cytidine residues boosts HIV-1 gene expression by increasing viral RNA stability

B. Cullen, R. Swanstrom, K. Tsai, 2020, bioRxiv.

MicroRNA expression by an oncogenic retrovirus

B. Cullen, 2012, Proceedings of the National Academy of Sciences.

A “microRNA-like” small RNA expressed by Dengue virus?

B. Cullen, M. Garcia-Blanco, C. Blair, 2014, Proceedings of the National Academy of Sciences.

The positive effect of the negative factor

B. Cullen, 1991, Nature.

Functional analysis of the Tat trans activator of human immunodeficiency virus type 2

S. Le, J. Maizel, M. Malim, 1989, Journal of virology.

Phosphorylation of the rev gene product of human immunodeficiency virus type 1

M. Malim, B. Cullen, J. Hauber, 1988, Journal of virology.

RNA conformational propensities determine cellular activity

Laura R. Ganser, B. Cullen, D. Herschlag, 2022, bioRxiv.

Functional Organization oftheBel-1 transActivator of HumanFoamyVirus

B. Cullen, F. He, 1993 .

Identification of the activation domain of equine infectious anemia virus rev

B. Cullen, S. Carpenter, K. Partin, 1993, Journal of virology.

Functional consequences of natural sequence variation in the activation domain of HIV-1 Rev.

B. Cullen, J. Caffrey, J. Hua, 1996, Virology.

Comparative analysis of Rev function in human immunodeficiency virus types 1 and 2

B. Cullen, E. Garrett, 1992, Journal of virology.

Role and Mechanism of Action of the HIV-1 Rev Regulatory Protein

B. Cullen, 2018 .

Posttranscriptional Regulation by the HIV-1 Rev Protein

B. Cullen, 1998 .

Conserved functional organization of the human immunodeficiency virus type 1 and visna virus Rev proteins

M. Malim, B. Cullen, L. Tiley, 1991, Journal of virology.

HIV-1 Packing to Leave

B. Cullen, 2014, Cell.

Utility of the secreted placental alkaline phosphatase reporter enzyme.

B. Cullen, 2000, Methods in enzymology.

MicroRNAs and small interfering RNAs can inhibit mRNA expression by similar mechanisms

B. Cullen, R. Yi, Yan Zeng, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Reconstitution of high affinity IL-2 receptor expression in a human T-cell line using a retroviral cDNA expression vector.

B. Cullen, W. Greene, N. Peffer, 1987, Molecular biology & medicine.

Downregulation of cell-surface CD4 expression by simian immunodeficiency virus Nef prevents viral super infection

B. Cullen, J. Ottinger, C. Doyle, 1993, The Journal of experimental medicine.

The peripheral myelin protein gene PMP–22 is contained within the Charcot–Marie–Tooth disease type 1A duplication

P. De Jonghe, K. Fischbeck, B. Cullen, 1992, Nature Genetics.

Virology. New trick from an old foe.

B. Cullen, 1996, Nature.

Localization and Membrane Topology of Coronavirus Nonstructural Protein 4: Involvement of the Early Secretory Pathway in Replication

D. Hazuda, B. Cullen, N. DeLuca, 2007, Journal of Virology.

Update on Alzheimer's Disease Therapy and Prevention Strategies.

B. Cullen, T. Sakmar, W. V. Graham, 2017, Annual review of medicine.

RNA interference does not function as an innate antiviral response in mammalian somatic cells

B. Cullen, 2011 .

Immunodeficiency Virus mRNAs Expression of Incompletely Spliced Human Factor Is Sufficient To Induce Cytoplasmic Recruitment of the Crm1 Nuclear Export

B. Cullen, R. Yi, H. Bogerd, 2014 .

HIV-1: Is Nef a PAK animal?

B. Cullen, 1996, Current Biology.

Viruses hijack a long non-coding RNA

B. Cullen, Nicholas S. Heaton, 2017, Nature.

Epstein-Barr Viruses (EBVs) Deficient in EBV-Encoded RNAs Have Higher Levels of Latent Membrane Protein 2 RNA Expression in Lymphoblastoid Cell Lines and Efficiently Establish Persistent Infections in Humanized Mice

B. Cullen, P. Farrell, C. Münz, 2015, Journal of Virology.

EBER RNAs give higher LMP 2 RNA expression in 1 lymphoblastoid cell lines and efficiently establish persistent infection in humanized mice 2 3

B. Cullen, Claudio Elgueta Karstegl, C. Münz, 2015 .

Analysis of Human Alphaherpesvirus MicroRNA Expression in Latently Infected Human Trigeminal Ganglia

B. Cullen, R. Cohrs, D. Gilden, 2009, Journal of Virology.

Structural requirements for pre-microRNA binding and nuclear export by Exportin 5.

B. Cullen, Yan Zeng, 2004, Nucleic acids research.

Inactivation of the Human Papillomavirus E6 or E7 Gene in Cervical Carcinoma Cells by Using a Bacterial CRISPR/Cas RNA-Guided Endonuclease

B. Cullen, M. Kastan, H. Bogerd, 2014, Journal of Virology.

RNA conformational propensities determine cellular activity

Laura R. Ganser, B. Cullen, D. Herschlag, 2023, Nature.

Optimization of a multiplex CRISPR/Cas system for use as an antiviral therapeutic.

B. Cullen, K. Tsai, H. Bogerd, 2015, Methods.

The HIV-1 REV Trans-Activator is a Sequence Specific RNA Binding Protein

M. Malim, B. Cullen, L. Tiley, 1990 .

Epigenetic and epitranscriptomic regulation of viral replication

B. Cullen, K. Tsai, 2020, Nature Reviews Microbiology.

Sequence requirements for ligand binding and cell surface expression of the Tac antigen, a human interleukin-2 receptor.

B. Cullen, F. Podlaski, W. Greene, 1988, The Journal of biological chemistry.

Correction and Clarification: Visna Virus Encodes a Post-Transcriptional Regulator of Viral Structural Gene Expression

S. Le, J. Maizel, B. Cullen, 1990 .

Functional domain organization of human APOBEC3G.

B. Cullen, B. Gooch, 2008, Virology.

Stabilizing non-native excited states as a therapeutic strategy for targeting RNA

Laura R. Ganser, B. Cullen, H. Bogerd, 2019 .