M. Caruthers

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Improved free-energy parameters for predictions of RNA duplex stability.

D. Turner, S. Freier, R. Kierzek, 1986, Proceedings of the National Academy of Sciences of the United States of America.

Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis

M. Caruthers, S. Beaucage, 1981 .

Chemical synthesis of deoxyoligonucleotides by the phosphoramidite method.

M. Caruthers, L. Mcbride, S. Beaucage, 1987, Methods in enzymology.

Synthesis of deoxyoligonucleotides on a polymer support

Mark D. Matteucci, M. Caruthers, M. Matteucci, 1981 .

Phosphoramidites as Synthons for Polynucleotide Synthesis

M. Caruthers, W. Brill, D. Dellinger, 1987 .

Synthesis of high-quality libraries of long (150mer) oligonucleotides by a novel depurination controlled process

Emily M. LeProust, Eugeni Namsaraev, M. Caruthers, 2010, Nucleic acids research.

Knowing Better and Losing Even More : The Use of Knowledge in Hazards Management

M. Caruthers, H. McCuen, M. Olesiak, 2015 .

Polymer-supported RNA synthesis and its application to test the nearest-neighbor model for duplex stability.

C. E. Longfellow, D. Turner, S. Freier, 1986, Biochemistry.

3 – DNA Synthesis for Nonchemists: The Phosphoramidite Method on Silica Supports

M. Caruthers, 1987 .

Mutants of the lac promoter with large insertions and deletions between the CAP binding site and the -35 region.

M. Caruthers, W. Mandecki, 1984, Gene.

Chemical synthesis of DNA and DNA analogs

M. Caruthers, Marvin H. Caruthers, 1991 .

DNA Analogues Modified at the Nonlinking Positions of Phosphorus.

M. Caruthers, Pawan Kumar, 2020, Accounts of chemical research.

Chemical Synthesis of DNA and DNA Analogues

M. Caruthers, 1992 .

Oligonucleotide syntheses utilizing beta-benzoylpropionyl, a blocking group with a trigger for selective cleavage.

M. Caruthers, R. Letsinger, P. Miller, 1967, Journal of the American Chemical Society.

The synthesis of oligodeoxyprimidines on a polymer support

M. Caruthers, M. Matteucci, 1980 .

Synthesis of oligodeoxynucleotides and oligodeoxynucleotide analogs using phosphoramidite intermediates

M. Caruthers, L. Mcbride, M. Dorman, 1984 .

Nucleotide chemistry. 16. Amidine protecting groups for oligonucleotide synthesis

R. Kierzek, M. Caruthers, L. Mcbride, 1986 .

Directed Arbuzov-type reactions of 2-cyano-1,1-dimethylethyl deoxynucleoside phosphites.

M. Caruthers, J. Nielsen, 1988, Journal of the American Chemical Society.

Synthesis of oligodeoxynucleoside phosphorodithioates via thioamidites

M. Caruthers, W. Brill, J.-Y. Tang, 1989 .

Antibodies specific for branched ribonucleic acids.

R. Kierzek, M. Caruthers, M. Edmonds, 1990, Analytical biochemistry.

Nucleic Acids Research Oligonucleotide mutagenesis of the lacPUV 5 promoter

M. Caruthers, W. Reznikoff, W. Mandecki, 2022 .

Comparative pharmacokinetics, tissue distribution, and tumor accumulation of phosphorothioate, phosphorodithioate, and methylphosphonate oligonucleotides in nude mice.

M. Caruthers, E. Wickstrom, R. Juliano, 1997, Antisense & nucleic acid drug development.

Chemical synthesis of deoxyoligonucleotides and deoxyoligonucleotide analogs.

M. Caruthers, G. Beaton, W. Wiesler, 1992, Methods in enzymology.

Synthesis of oligonucleotide phosphorodithioates

M. Caruthers, G. Beaton, W. Brill, 1992 .

Synthesis of deoxyoligonucleotides on a polymer support

M. Caruthers, M. Matteucci, 1981 .

Inhibition of the erbB-2 tyrosine kinase receptor in breast cancer cells by phosphoromonothioate and phosphorodithioate antisense oligonucleotides.

M. Caruthers, J. Iglehart, J. Mills, 1996, Nucleic acids research.

Oxidative substitution of boranephosphonate diesters as a route to post-synthetically modified DNA.

M. Caruthers, R. Shoemaker, Subhadeep Roy, 2015, Journal of the American Chemical Society.

Solid-Phase Synthesis, Hybridizing Ability, Uptake, and Nuclease Resistant Profiles of Position-Selective Cationic and Hydrophobic Phosphotriester Oligonucleotides.

M. Caruthers, L. Monfregola, 2015, The Journal of organic chemistry.

Chemical synthesis and biological studies on mutated gene-control regions.

M. Caruthers, W. Mandecki, P. Dehaseth, 1983, Cold Spring Harbor Symposia on Quantitative Biology.

Control of adenovirus E1B mRNA synthesis by a shift in the activities of RNA splice sites

M. Caruthers, C. Montell, A. Berk, 1984, Molecular and cellular biology.

by a shift in the activities of RNA splice sites. Control of adenovirus E1B mRNA synthesis

M. Caruthers, C. Montell, A. Berk, 2013 .

Control ofAdenovirus E1BmRNA Synthesis bya Shift inthe Activities ofRNA Splice Sites

M. Caruthers, A. Berk, 1984 .

Synthesis of Phosphorodiamidate Morpholino Oligonucleotides and Their Chimeras Using Phosphoramidite Chemistry.

M. Caruthers, Sibasish Paul, 2016, Journal of the American Chemical Society.

Synthesis and Characterization of Thiophosphoramidate Morpholino Oligonucleotides and Chimeras.

M. Caruthers, K. Jastrzębska, Heera K. Langner, 2020, Journal of the American Chemical Society.

Truncated RNA-binding protein production by DUX4-induced systemic inhibition of nonsense-mediated RNA decay

Austin E. Gillen, M. Caruthers, Michael A. Cortazar, 2022, bioRxiv.

Studies on gene control regions. 1. Chemical synthesis of lactose operator deoxyribonucleic acid segments.

M. Caruthers, D. Goeddel, D. Yansura, 1977, Biochemistry.

N6(N-methyl-2-pyrrolidine amidine)deoxyadenosine - a new deoxynucleoside protecting group

M. Caruthers, L. Mcbride, 1983 .

Color coded triarylmethyl protecting groups useful for deoxypolynucleotide synthesis.

M. Caruthers, E. Fisher, 1983, Nucleic acids research.

Total synthesis of the structural gene for the precursor of a tyrosine suppressor transfer RNA from Escherichia coli. 1. General introduction.

M. Caruthers, H. Khorana, A. Kumar, 1976, The Journal of biological chemistry.

SYNTHESIS OF SEQUENCE DEFINED POLYNUCLEOTIDES VIA DIESTER, TRIESTER AND PHOSPHITE COUPLING METHODS

M. Caruthers, 1981 .

Cellular pharmacology and protein binding of phosphoromonothioate and phosphorodithioate oligodeoxynucleotides: a comparative study.

M. Caruthers, J. Tonkinson, L. Yakubov, 1994, Antisense research and development.

Thiomorpholino oligonucleotides as a robust class of next generation platforms for alternate mRNA splicing

M. Caruthers, R. Veedu, Bao T. Le, 2022, Proceedings of the National Academy of Sciences of the United States of America.

Synthesis and Preliminary Biochemical Studies with 5'-Deoxy-5'-methylidyne Phosphonate Linked Thymidine Oligonucleotides

M. Caruthers, Zhengyun Zhao, 1996 .

Chemical Synthesis of Deoxyoligonucleotides and Deoxyoligonucleotide Analogs

M. Caruthers, G. Beaton, W. Wiesler, 1993 .

A New Method for Synthesizing RNA on Silica Supports

M. Caruthers, D. Dellinger, 1987 .

Synthesis and Biological Activity of Phosphonocarboxylate DNA

M. Caruthers, D. Dellinger, C. Yamada, 2007, Nucleosides, nucleotides & nucleic acids.

Solid-phase chemical synthesis of phosphonoacetate and thiophosphonoacetate oligodeoxynucleotides.

M. Caruthers, D. Dellinger, N. Christensen, 2003, Journal of the American Chemical Society.

Chemical Synthesis and biochemical reactivity of bacterlophage bambda pR promoter

M. Caruthers, P. Dehaseth, R. Goldman, 1983 .

New chemical methods for synthesizing polynucleotides.

M. Caruthers, S. Beaucage, J. Efcavitch, 1980, Nucleic acids symposium series.

Detection and characterization of a factor which rescues spliceosome assembly from a heat-inactivated HeLa cell nuclear extract

M. Caruthers, P. Delannoy, 1991, Molecular and cellular biology.

Synthesis of Oligonucleotides and Oligonucleotide Analogues

M. Caruthers, 1989 .

Modern methods of nucleic acid synthesis on polymeric supports

M. Caruthers, 1987 .

Studies on Nucleotide Chemistry 15. Synthesis of Oligodeoxynucleotides Using Amidine Protected Nucleosides

M. Caruthers, L. Mcbride, L. Bracco, 1985 .

Isolation and characterization of a cDNA clone for bovine cytochrome c oxidase subunit IV.

M. I. Lomax, M. Caruthers, L. Grossman, 1984, Proceedings of the National Academy of Sciences of the United States of America.

In situ acttvadon of bis-dialkytam inophosphines - a new method for synthesizing deoxyotigonudeoddes on polymer supports

M. Caruthers, A. Barone, Y. Tang, 1984 .

Metal ions as selective triggers for removing oligodeoxynucleotide phosphotriester protecting groups

M. Caruthers, Y. Stabinsky, R. Sakata, 1982 .

Reactions of nucleosides on polymer supports. Synthesis of thymidylylthymidylylthymidine.

M. Caruthers, D. Jerina, R. Letsinger, 1967, Biochemistry.

How lac repressor recognizes lac operator.

M. Caruthers, D. Goeddel, D. Yansura, 1978, Proceedings of the National Academy of Sciences of the United States of America.

The use of zinc bromide for removal of dimethoxytrityl ethers from deoxynucleosides

M. Caruthers, M. Matteucci, 1980 .

Total Synthesis of the Gene for an Alanine Transfer Ribonucleic Acid from Yeast

K. L. Agarwal, H. G. Khorana, V. Sgaramella, 1970, Nature.

Synthetic Strategies and Parameters Involved in the Synthesis of Oligodeoxyribonucleotides According to the Phosphoramidite Method

M. Caruthers, S. Beaucage, 2000, Current protocols in nucleic acid chemistry.

Synthesis of deoxydinucleoside phosphorodithioates

M. Caruthers, W. Brill, J. Nielsen, 1991 .

Synthesis of mixed sequence borane phosphonate DNA.

M. Caruthers, A. Higson, H. McCuen, 2006, Journal of the American Chemical Society.

Chemical synthesis of an oligodeoxythymidylate containing boranephosphate and phosphate linkages

M. Caruthers, Heather A. Brummel, 2002 .

Synthesis of an oligothymidylate containing boranophosphate linkages

M. Caruthers, A. Higson, A. Sierzchala, 1998 .

An investigation of several deoxynucleoside phosphoramidites useful for synthesizing deoxyoligonucleotides

M. Caruthers, L. Mcbride, Marvin H. Caruthers, 1983 .

Metal ion catalysis in the Tetrahymena ribozyme reaction

M. Caruthers, T. Cech, J. Piccirilli, 1993, Nature.

Synthesis of 5′-deoxy-5′-methylphosphonate linked thymidine oligonucleotides.

M. Caruthers, D. Graff, M. Bohringer, 1993 .

Phosphorodithioate DNA as a potential therapeutic drug.

M. Caruthers, W. Marshall, 1993, Science.

Novel RNA Synthesis Method Using 5‘-O-Silyl-2‘-O-orthoester Protecting Groups

M. Caruthers, S. Scaringe, F. Wincott, 1998 .

Synthesis of Phosphorodithioate DNA via Sulfur-Linked, Base-Labile Protecting Groups(1).

M. Caruthers, W. Wiesler, 1996, The Journal of organic chemistry.

Synthesis of (pentacarbonyl)tungstate(−1) and (pentacarbonyl)molybdate(−1) dinucleotides

M. Caruthers, O. Páv, 2009 .

Deciphering the protein-DNA recognition code

M. Caruthers, 1980 .

Biochemical properties of phosphonoacetate and thiophosphonoacetate oligodeoxyribonucleotides.

M. Caruthers, D. Dellinger, Benjamin D Lunstad, 2003, Nucleic acids research.

Gene synthesis machines: DNA chemistry and its uses.

M. Caruthers, M H Caruthers, 1985, Science.

A microchemical facility for the analysis and synthesis of genes and proteins

L. Hood, M. Hunkapiller, T. Hunkapiller, 1984, Nature.

An electrospray mass spectrometric method for accurate mass determination of highly acid-sensitive phosphoramidites.

M. Caruthers, Z. Darula, D. Dellinger, 2008, Rapid communications in mass spectrometry : RCM.

ACCURATE MASS ANALYSIS OF PHOSPHORAMIDITES BY ELECTROSPRAY MASS SPECTROMETRY

M. Caruthers, D. Dellinger, Z. Tímár, 2005, Nucleosides, nucleotides & nucleic acids.

Studied on gene control regions IX. The effect of hypoxanthine-substituted lac operators on the lac operator--lac repressor interaction.

M. Caruthers, D. Goeddel, D. Yansura, 1979, Journal of molecular biology.

Cloning of chemically synthesized lactose operators.

M. Caruthers, D. Goeddel, D. Yansura, 1977, Gene.

Iac operon operator DNA: isolation and trimming for NMR spectroscopy.

M. Caruthers, P. Lu, H. Nick, 1982, Analytical biochemistry.

Synthesis of dinucleoside and dinucleotide phosphorodithioates via a phosphotriester approach

M. Caruthers, Y. Ma, E. Yau, 1990 .

Solid-phase synthesis, thermal denaturation studies, nuclease resistance, and cellular uptake of (oligodeoxyribonucleoside)methylborane phosphine-DNA chimeras.

M. Caruthers, Heera Krishna, 2011, Journal of the American Chemical Society.

In situ activation of bis-dialkylaminophosphines--a new method for synthesizing deoxyoligonucleotides on polymer supports.

M. Caruthers, A. Barone, J. Tang, 1984, Nucleic acids research.

Amidine protecting groups for oligonucleotide synthesis

R. Kierzek, M. Caruthers, L. Mcbride, 1986 .

Chemical synthesis of branched RNA.

R. Kierzek, M. Caruthers, M. Edmonds, 1986, Nucleic acids research.

Base substitution mutants of the lac operator: in vivo and in vitro affinities for lac repressor.

F Buck, M. Caruthers, F. Buck, 1986, Gene.

Studies on gene control regions. VII. Effect of 5-bromuracil-substituted lac operators on the lac operator-lac repressor interaction.

M. Caruthers, D. Goeddel, D. Yansura, 1978, Journal of molecular biology.

Studies on gene control regions. VI. The 5- methyl of thymine, a lac repressor recognition site.

M. Caruthers, D. Goeddel, D. Yansura, 1977, Nucleic acids research.

Studies on gene control regions. 2. Enzymatic joining of chemically synthesized lactose operator deoxyribonucleic acid segments.

M. Caruthers, D. Goeddel, D. Yansura, 1977, Biochemistry.

Studies of gene control regions. III. Binding of synthetic and modified synthetic lac operator DNAs to lactose repressor.

M. Caruthers, D. Goeddel, D. Yansura, 1977, Nucleic acids research.

Stereoselective synthesis, chemistry and antiviral evaluation of 1-(2,3-dideoxy-3-C-hydroxymethyl-beta-D-threo-pentofuranosyl)thymine derivatives.

M. Caruthers, R. Schinazi, J. Wengel, 1995, Bioorganic & Medicinal Chemistry.

Synthesis of 5′-phosphonate linked thymidine deoxyoligonucleotides

M. Caruthers, T. Kofoed, 1996 .

Interactions between single‐stranded DNA binding protein and oligonucleotide analogs with different backbone chemistries

M. Caruthers, E. Wickstrom, R. Juliano, 1997, Journal of molecular recognition : JMR.

CX. Total synthesis of the structural gene for an alanine transfer ribonucleic acid from yeast. Synthesis of three decadeoxynucleotides corresponding to the nucleotide sequence 51 to 70.

M. Caruthers, H. Khorana, J. Van De Sande, 1972, Journal of molecular biology.

CXI. Total synthesis of the structural gene for an alanine transfer ribonucleic acid from yeast. Synthesis of a dodecadeoxynucleotide and a heptadeoxynucleotide corresponding to the nucleotide sequence 66 to 77.

M. Caruthers, H. Khorana, 1972, Journal of Molecular Biology.

Synthesis of dinucleoside phosphoramidimidates

M. Caruthers, O. Dahl, Kirsten Bjerg»rde, 1994 .

Synthesis of DNA/RNA and Their Analogs via Phosphoramidite and H-Phosphonate Chemistries

M. Caruthers, Subhadeep Roy, Subhadeep Roy, 2013, Molecules.

Synthesis of phosphorodithioate DNA by the H-phosphonothioate method

M. Caruthers, P. Seeberger, G. Beaton, 1999 .

Oxidative formation of phosphorodithioates via H-phosphonodithioates

M. Caruthers, P. Seeberger, 1995 .

Chemical and Biochemical Studies with Dithioate DNA

M. Caruthers, P. Shankland, L. Cummins, 1991 .

Oxidative and nonoxidative formation of internucleotide linkages

M. Caruthers, W. Brill, E. Yau, 1989 .

Synthesis and characterization of dinucleoside phosphorodithioates

M. Caruthers, W. Brill, J. Nielsen, 1988 .

Inhibition of human immunodeficiency virus activity by phosphorodithioate oligodeoxycytidine.

M. Caruthers, C. Stein, G. Beaton, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Total synthesis of the structural gene for the precursor of a tyrosine suppressor transfer RNA from Escherichia coli. 5. Synthesis of the deoxyribopolynucleotide segments representing the nucleotide sequence 71-103.

M. Caruthers, H. Khorana, M. Fridkin, 1976, The Journal of biological chemistry.

CIII. Total synthesis of the structural gene for an alanine transfer ribonucleic acid from yeast

M. Caruthers, H. Khorana, N. Gupta, 1972 .

Streamlined process for the chemical synthesis of RNA using 2'-O-thionocarbamate-protected nucleoside phosphoramidites in the solid phase.

James A. Powell, J. Myerson, M. Caruthers, 2011, Journal of the American Chemical Society.

Alkynyl phosphonate DNA: a versatile "click"able backbone for DNA-based biological applications.

M. Caruthers, Heera Krishna, 2012, Journal of the American Chemical Society.

O-aryl phosphoramidites: synthesis, reactivity and evaluation of their use for solid-phase synthesis of oligonucleotides

M. Caruthers, R. Eritja, V. Smirnov, 1990 .

Solid-phase oligodeoxynucleotide synthesis: a two-step cycle using peroxy anion deprotection.

J. Betley, M. Caruthers, D. Dellinger, 2003, Journal of the American Chemical Society.

Methylphosphonates as probes of protein-nucleic acid interactions.

M. Caruthers, E. Fisher, S. Noble, 1984, Nucleic acids research.

Synthesis and p-diastereomeric resolution of nucleoside 3′-O(s-alkyl) and nucleoside 3′-O(s-aryl) methylphosphonothioates

M. Caruthers, W. Brill, 1988 .

Synthesis of nucleoside methylphosphonothioates

M. Caruthers, W. Brill, 1987 .

A brief review of DNA and RNA chemical synthesis.

M. Caruthers, Marvin H Caruthers, 2011, Biochemical Society transactions.

Studies on polynucleotides. 103. Total synthesis of the structural gene for an alanine transfer ribonucleic acid from yeast.

M. Caruthers, H. Khorana, N. Gupta, 1972, Journal of molecular biology.

Studies on polynucleotides. CXVII. Hybridization of polydeoxynucleotides with tyrosine transfer RNA sequences to the r-strand of phi80psu + 3 DNA.

M. Caruthers, H. Khorana, A. Kumar, 1972, Journal of molecular biology.

Resolving the functions of overlapping viral genes by site-specific mutagenesis at a mRNA splice site

Craig Montell, M. Caruthers, C. Montell, 1982, Nature.

Synthesis of deoxycytidine oligomers containing phosphorodithioate linkages

M. Caruthers, J. Nielsen, W. Marshall, 1989 .

Synthesis of dinucleoside phosphorodithioates via thioamidites

M. Caruthers, W. Brill, J. Nielsen, 1988 .

Solid-phase synthesis and biochemical studies of O-boranophosphopeptides and O-dithiophosphopeptides.

M. Caruthers, P. Seeberger, A. Higson, 2002, Journal of the American Chemical Society.

5‘-Dithiophosphoryl Deoxyoligonucleotides: Synthesis and Biological Studies1

M. Caruthers, P. Seeberger, G. Beaton, 1996 .

Biochemical and physicochemical properties of phosphorodithioate DNA.

M. Caruthers, L. Cummins, G. Beaton, 1996, Biochemistry.

2'-Deoxynucleoside Dithiophosphates: Synthesis and Biological Studies1

M. Caruthers, P. Seeberger, E. Yau, 1995 .

Synthesis of a dinucleotide phosphoramidimidate

M. Caruthers, Reto W. Fischer, R. Fischer, 1995 .

Synthesis of Dinucleoside Phosphoramidimidates.

M. Caruthers, O. Dahl, K. Bjergårde, 1994 .

Synthesis and purification of phosphorodithioate DNA.

M. Caruthers, W. Wiesler, W. Marshall, 1993, Methods in molecular biology.

Synthesis of Oligodeoxynlicleotides Containing Specific Methylphosphonothioate and Dithioate Moieties

M. Caruthers, W. Brill, 1989 .

Oxidative Formation of Phosphorodithioates via H‐Phosphonodithioates.

M. Caruthers, P. Seeberger, 1995 .

Oxidative and Nonoxidative Formation of Internucleotide Linkages.

M. Caruthers, W. Brill, E. Yau, 1990 .

Synthesis and Characterization of Dinucleoside Phosphorodithioates.

M. Caruthers, W. Brill, J. Nielsen, 1988 .

Synthesis of phosphorodithioate RNA by the H-phosphonothioate method

M. Caruthers, P. Seeberger, C. Greef, 1996 .

Synthesis and biological activity of phosphonoacetate- and thiophosphonoacetate-modified 2'-O-methyl oligoribonucleotides.

M. Caruthers, A. Krivenko, A. Torres, 2012, Organic & biomolecular chemistry.

Inhibition of RNA cleavage but not polyadenylation by a point mutation in mRNA 3′ consensus sequence AAUAAA

Craig Montell, M. Caruthers, C. Montell, 1983, Nature.

Chapter 27. Sequencing and Synthesis of Nucleic Acids

M. Caruthers, 1981 .

Improved Parameters for Prediction of RNA Secondary Structure and Insights into why RNA forms Double Helixes

D. Turner, S. Freier, R. Kierzek, 1986 .

Nuclear compartmentalization of TERT mRNA and TUG1 lncRNA is driven by intron retention

J. Rinn, B. Blencowe, M. Caruthers, 2021, Nature Communications.

Nuclear compartmentalization of TERT mRNA and TUG1 lncRNA transcripts is driven by intron retention: implications for RNA-directed therapies

J. Rinn, B. Blencowe, M. Caruthers, 2020, bioRxiv.

Gene Synthesis — Toward a Future World

M. Caruthers, 1984 .

NEW METHODS FOR CHEMICALLY SYNTHESIZING DEOXYOLIGONUCLEOTIDES

M. Caruthers, 1984 .

Studies on gene control regions XII. The functional significance of a lac operator constitutive mutation.

M. Caruthers, E. Fisher, M H Caruthers, 1979, Nucleic acids research.

Binding of synthetic lactose operator DNAs to lactose represessors.

M. Caruthers, D. Goeddel, D. Yansura, 1977, Proceedings of the National Academy of Sciences of the United States of America.

Point mutations of the adenovirus major late promoter with different transcriptional efficiencies in vitro.

M. Caruthers, R. Weinmann, M. Concino, 1983, The Journal of biological chemistry.

Cloning of chemically synthesized lactose operators. II. EcoRI-linkered operators.

M. Caruthers, D. Goeddel, D. Yansura, 1978, Gene.

Stability of XGCGCp, GCGCYp, and XGCGCYp helixes: an empirical estimate of the energetics of hydrogen bonds in nucleic acids.

D. Turner, S. Freier, R. Kierzek, 1986, Biochemistry.

Free energy contributions of G.U and other terminal mismatches to helix stability.

D. Turner, S. Freier, R. Kierzek, 1986, Biochemistry.

Exploring site‐specific activation of bis‐N,N’‐dialkylaminophosphordiamidites and the synthesis of morpholinophosphoramidate oligonucleotides

M. Caruthers, K. Jastrzębska, Heera Krishna, 2019, FEBS letters.

The Chemical Synthesis of DNA/RNA: Our Gift to Science

M. Caruthers, Marvin H. Caruthers, 2012, The Journal of Biological Chemistry.

Interaction of AD2+D2 protein and simian virus 40 large T antigen with the large tumor antigen binding site I.

R. Tjian, M. Caruthers, R. Meyers, 1984, Biochemistry.

Synthesis of the nutL DNA segments and analysis of antitermination and termination functions in coliphage lambda.

M. Caruthers, W. Szybalski, G. Galluppi, 1982, Gene.

THE SYNTHESIS AND BIOCHEMICAL REACTIVITY OF BIOLOGICALLY IMPORTANT GENES AND GENE CONTROL REGIONS

M. Caruthers, 1982 .

A calorimetric investigation of the interaction of the lac repressor with inducer.

M. Caruthers, S. Gill, J. Donnér, 1982, The Journal of biological chemistry.

Silver nanoassemblies constructed from boranephosphonate DNA.

M. Caruthers, M. Olesiak, Subhadeep Roy, 2013, Journal of the American Chemical Society.

Synthesis and biological activity of a lambda pseudo operator.

M. Caruthers, E. Kawashima, T. Gadek, 1977, Biochemistry.

Antisense DNA downregulation of the ERBB2 oncogene measured by a flow cytometric assay.

M. Caruthers, P. Davis, J. Iglehart, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Synthesis of DNA/RNA and Their Analogs via Phosphoramidite and H-Phosphonate Chemistries

M. Caruthers, Subhadeep Roy, Subhadeep Roy, 2013, Molecules.

Total synthesis of the structural gene for the precursor of a tyrosine suppressor transfer RNA from Escherichia coli. 6. Synthesis of the deoxyribopolynucleotide segments corresponding to the nucleotide sequence 100-126.

M. Caruthers, H. Khorana, J. Van De Sande, 1976, Journal of Biological Chemistry.

Total synthesis of the structural gene for the precursor of a tyrosine suppressor transfer RNA from Escherichia coli. 10. Enzymatic joining of chemically synthesized segments to form the DNA duplex corresponding to the nucleotide sequence 86-126.

M. Caruthers, H. Khorana, K. Kleppe, 1976, The Journal of biological chemistry.

Progress in the total synthesis of the gene for ala-tRNA.

M. Caruthers, H. Khorana, N. Gupta, 1968, Cold Spring Harbor symposia on quantitative biology.

Pyridinium Boranephosphonate Modified DNA Oligonucleotides.

M. Caruthers, Subhadeep Roy, R. Kundu, 2017, The Journal of organic chemistry.

Oligodeoxynucleotides containing 2'-amino-LNA nucleotides as constrained morpholino phosphoramidate and phosphorodiamidate monomers.

M. Caruthers, J. Wengel, T. Kosbar, 2017, Bioorganic & medicinal chemistry letters.

Synthesis and biochemical evaluation of phosphonoformate oligodeoxyribonucleotides.

M. Caruthers, D. Dellinger, Christina M. Yamada, 2006, Journal of the American Chemical Society.

Boranephosphonate DNA-Mediated Metallization of Single-Walled Carbon Nanotubes

M. Caruthers, J. Cha, Omer Yehezkeli, 2017 .

Formation of Silver Nanostructures by Rolling Circle Amplification Using Boranephosphonate-Modified Nucleotides.

M. Caruthers, Xiaoyan Qian, M. Nilsson, 2015, Analytical chemistry.

Reduction of metal ions by boranephosphonate DNA.

M. Caruthers, H. McCuen, M. Olesiak, 2012, Organic & biomolecular chemistry.

Synthesis And Biological Activity of Borane Phosphonate DNA

M. Caruthers, A. Krivenko, M. Olesiak, 2011 .

Synthesis and Biochemical Activity of New Oligonucleotide Analogs

M. Caruthers, A. Higson, H. McCuen, 2008 .

Effect of 2′-O-methyl/thiophosphonoacetate-modified antisense oligonucleotides on huntingtin expression in patient-derived cells

M. Caruthers, D. Corey, Masayuki Matsui, 2014, Artificial DNA, PNA & XNA.

Oligodeoxyribonucleotide Analogs Functionalized with Phosphonoacetate and Thiophosphonoacetate Diesters

M. Caruthers, D. Dellinger, Douglas J. Dellinger, 2004, Current protocols in nucleic acid chemistry.

Nucleic Acids Research

M. Caruthers, D. Yansura, 2003 .

CXV. Total synthesis of the structural gene for an alanine transfer RNA from yeast. Enzymic joining to form the total DNA duplex.

M. Caruthers, H. Khorana, N. Gupta, 1972, Journal of molecular biology.

CXIV. Total synthesis of the structural gene for an alanine transfer RNA from yeast. Enzymic joining of the chemically synthesized segments to form the DNA duplex corresponding to nucleotide sequence 46 to 77.

M. Caruthers, H. Khorana, J. Van De Sande, 1972, Journal of molecular biology.

Compromised nonsense-mediated RNA decay results in truncated RNA-binding protein production upon DUX4 expression

M. Caruthers, Michael A. Cortazar, S. Floor, 2023, Cell reports.

lac repressor-lac operator interaction: NMR observations.

M. Caruthers, K. Arndt, P. Lu, 1982, Proceedings of the National Academy of Sciences of the United States of America.

Synthesis of Backbone-Modified Morpholino Oligonucleotides Using Phosphoramidite Chemistry

M. Caruthers, Sibasish Paul, 2023, Molecules.

Peptide-substituted oligonucleotide synthesis and non-toxic, passive cell delivery

M. Caruthers, Shiying Shang, L. Monfregola, 2016, Signal Transduction and Targeted Therapy.

Gene synthesis with H G Khorana

M. Caruthers, 2012 .

Gene synthesis with H G Khorana

M. Caruthers, 2012, Resonance.

Deoxyoligonucleotide synthesis via the phosphoramidite method.

M. Caruthers, L. Mcbride, P. Dehaseth, 1984, Gene amplification and analysis.

lac Up-promoter mutants with increased homology to the consensus promoter sequence

M. Caruthers, W. Mandecki, B. Powell, 1985, Journal of bacteriology.

Studies on gene control regions X. The effect of specific adenine-thymine transversions on the lac repressor-lac operator interaction.

M. Caruthers, H. Sista, R. Loder, 1979, Nucleic acids research.

Synthesis of Small-Molecule/DNA Hybrids through On-Bead Amide-Coupling Approach.

M. Caruthers, J. Cha, Yinghua Jin, 2017, The Journal of organic chemistry.

Phosphorodithioate DNA as a Potential Therapeutic Drug

M. Caruthers, W. Marshall, 1993 .

Altered Cro repressors from engineered mutagenesis of a synthetic cro gene.

M. Caruthers, L. Bracco, D. Dodds, 1985, Proceedings of the National Academy of Sciences of the United States of America.

Directed Arbuzov‐Type Reactions of 2‐Cyano‐1,1‐dimethylethyl Deoxynucleoside Phosphites.

M. Caruthers, J. Nielsen, 1988 .

Oligonucleotide mutagenesis of the lacPUV5 promoter.

M. Caruthers, W. Reznikoff, W. Mandecki, 1984, Nucleic acids research.

Role of the Cro repressor carboxy-terminal domain and flexible dimer linkage in operator and nonspecific DNA binding.

M. Caruthers, L. Bracco, G. Beaton, 1990, Biochemistry.

Solid-phase synthesis, thermal denaturation studies, nuclease resistance, and cellular uptake of (oligodeoxyribonucleoside)methylborane phosphine-DNA chimeras.

M. Caruthers, Heera Krishna, 2011, Journal of the American Chemical Society.

The tetrahymena ribozyme cleaves a 5'-methylene phosphonate monoester approximately 10(2)-fold faster than a normal phosphate diester: implications for enzyme catalysis of phosphoryl transfer reactions.

M. Caruthers, J. Piccirilli, M. Boehringer, 2001, Biochemistry.

Synthesis of deoxyoligonucleotides on a polymer support. 1981.

M. Caruthers, M. Matteucci, 1992, Biotechnology.

An electrospray mass spectrometric method for accurate mass determination of highly acid-sensitive phosphoramidites.

M. Caruthers, Z. Darula, D. Dellinger, 2008, Rapid communications in mass spectrometry : RCM.

Binding studies of SV40 T-antigen to SV40 binding site II.

M. Caruthers, P. Gottlieb, M. Nasoff, 1985, Nucleic acids research.

Altered Cro repressors from engineered mutagenesis of a synthetic cro gene.

M. Caruthers, L. Bracco, D. Dodds, 1985, Proceedings of the National Academy of Sciences of the United States of America.