B. Ganem

发表

B. Ganem, 1987, Nature.

SHIKIMATE-DERIVED METABOLITES. 13. A KEY INTERMEDIATE IN THE BIOSYNTHESIS OF ANTHRANILATE FROM CHORISMATE

B. Ganem, Chia-Yu P. Teng, 1984 .

Total synthesis of (.+-.)-4-amino-4-deoxychorismic acid: a key intermediate in the biosynthesis of p-aminobenzoic acid and L-p-aminophenylalanine

B. Ganem, R. Bhatnagar, L. Vining, 1985 .

The mechanism of rearrangement of chorismic acid and related compounds

B. Ganem, J. Gajewski, J. Jurayj, 1987 .

A genetically engineered monofunctional chorismate mutase

B. Ganem, J. Stewart, David B. Wilson, 1990 .

New insight into the catalytic mechanism of chorismate mutases from structural studies.

B. Ganem, J. Clardy, J. Stewart, 1995, Chemistry & biology.

ATOMIC-STRUCTURE OF THE BURIED CATALYTIC POCKET OF ESCHERICHIA-COLI CHORISMATE MUTASE.

P. Karplus, B. Ganem, J. Clardy, 1995 .

Thermodynamics of a transition state analogue inhibitor binding to Escherichia coli chorismate mutase: probing the charge state of an active site residue and its role in inhibitor binding and catalysis.

B. Ganem, J. Clardy, J. Erickson, 1998, Biochemistry.

Regulation of phenylalanine biosynthesis. Studies on the mechanism of phenylalanine binding and feedback inhibition in the Escherichia coli P-protein.

B. Ganem, D. Wilson, G. Pohnert, 1999, Biochemistry.

Probing the catalytic mechanism of prephenate dehydratase by site-directed mutagenesis of the Escherichia coli P-protein dehydratase domain.

B. Ganem, D. Wilson, S. Zhang, 2000, Biochemistry.

Strategies for innovation in multicomponent reaction design.

Bruce Ganem, B. Ganem, 2009, Accounts of chemical research.

Effectiveness of natural and synthetic complexes of porin and O polysaccharide as vaccines against Brucella abortus in mice

B. Ganem, G. Rowe, A. Winter, 1988, Infection and immunity.

Use of multicomponent reactions in developing small-molecule tools to study GABAA receptor mechanism and function.

R. W. Lewis, B. Ganem, G. P. Hess, 2011, Future medicinal chemistry.

Trifluoroacetic anhydride-catalyzed oxidation of isonitriles by DMSO: a rapid, convenient synthesis of isocyanates.

B. Ganem, H. Le, 2011, Organic letters.

Differentiation of diols; A new synthesis of bromoformates and protected hydroxyaldehydes

B. Ganem, R. K. Boeckman, 1974 .

New methods for the oxidation of aldehydes to carboxylic acids and esters

B. Ganem, E. Corey, N. W. Gilman, 1968 .

A Simple, General Synthesis of Carbonimidic Dichlorides.

B. Ganem, H. Le, Claire M. Gober, 2012, Tetrahedron letters.

The hydrolysis of amines to alcohols: Clues from chorismate processing enzymes

B. Ganem, 1995 .

Alkylation of beta-(Hydroxymethyl)pyrroles: A New Synthesis of Porphobilinogen and Other Trisubstituted Pyrroles for Photodynamic Therapy.

B. Ganem, Christine Y. De Leon, 1996, The Journal of organic chemistry.

Site-directed mutagenesis of monofunctional chorismate mutase engineered from the E. coli P-protein.

B. Ganem, J. Clardy, D. Wilson, 1996, Bioorganic & medicinal chemistry.

An engineered chorismate mutase with allosteric regulation.

B. Ganem, D. Wilson, S. Zhang, 2003, Bioorganic & medicinal chemistry.

Chorismate mutase/prephenate dehydratase from Escherichia coli : subcloning, overproduction and purification

B. Ganem, D. Wilson, J. Stewart, 1991 .

ENANTIOSELECTIVE APPROACHES TO AMINOCYCLOPENTITOLS : A TOTAL SYNTHESIS OF (+)-6-EPITREHAZOLIN AND A FORMAL TOTAL SYNTHESIS OF (+)-TREHAZOLIN

B. Ganem, Jun Li, F. Lang, 1998 .

Chemistry of naturally occurring polyamines. VIII: Total synthesis of (+)-hypusine

B. Ganem, C. Tice, 1983 .

Recognition of cell‐wall peptide ligands by vancomycin group antibiotics: Studies using ion spray mass spectrometry

B. Ganem, J. Henion, H. Lim, 1995 .

Detection of noncovalent FKBP-FK506 and FKBP-Rapamycin complexes by capillary electrophoresis-mass spectrometry and capillary electrophoresis-tandem mass spectrometry

B. Ganem, J. Henion, Jianyi Cai, 1995, Journal of the American Society for Mass Spectrometry.

Studies on the distribution of oligodeoxynucleotide charge states in the gas phase by ion spray mass spectrometry

B. Ganem, J. Henion, X. Tong, 1995 .

Mass spectrometric studies on noncovalent dimers of leucine zipper peptides

B. Ganem, F. McLafferty, J. Henion, 1993 .

Detection of oligonucleotide duplex forms by ion-spray mass spectrometry

B. Ganem, J. Henion, Yanbin Li, 1993 .

Easy assembly of ligands for glycosidase affinity chromatography.

B. Ganem, R. Bernotas, 1990, The Biochemical journal.

Alkylation of nucleic acids by the antitumor agent COMC.

B. Ganem, D. Fabris, D. J. Creighton, 2002, Organic letters.

A novel inhibitor of human α-L-fucosidase: Enantioselective synthesis of L-fucoamidrazone

B. Ganem, B. Bowen, D. Schedler, 1994 .

Kinetic monitoring of enzymatic reactions in real time by quantitative high-performance liquid chromatography-mass spectrometry.

B. Ganem, J. Henion, T. Wachs, 1995, Analytical biochemistry.

Polyamines with N-(3-phenylpropyl) substituents are effective competitive inhibitors of trypanothione reductase and trypanocidal agents.

Matthew T. Hancock, B. Ganem, D. Rattendi, 2001, Bioorganic & medicinal chemistry letters.

Structural and stereochemical studies of potent inhibitors of glucosylceramide synthase and tumor cell growth.

B. Ganem, A. Abe, N. Radin, 1995, Journal of lipid research.

Amidine, amidrazone, and amidoxime derivatives of monosaccharide aldonolactams: synthesis and evaluation as glycosidase inhibitors

G. Papandreou, B. Ganem, Michael K. Tong, 1993 .

The chemistry of naturally occurring polyamines. 1. Total synthesis of celacinnine, celabenzine and maytenine

B. Ganem, J. McManis, 1980 .

A new approach to porphobilinogen and its analogs

B. Ganem, C. Leon, 1997 .

Analysis of the Energetics of Gas-Phase Immunophilin-Ligand Complexes by Ion Spray Mass Spectrometry

B. Ganem, J. Henion, T. Ocain, 1994 .

Fabrication of patterned organic thin film by low-energy electron beam lithography and surface-initiated ring-opening metathesis polymerization

B. Ganem, Zhebo Ding, 2006 .

Dihydropyrimidinone Positive Modulation of Delta Subunit-containing GABA A Receptors, Including an Epilepsy-linked Mutant Variant

B. Ganem, Kyle P. Eagen, G. P. Hess, 2016 .

Synthesis of glycolipid analogues that disrupt binding of HIV-1 gp120 to galactosylceramide.

B. Ganem, J. Fantini, D. Hammache, 2000, Bioorganic & medicinal chemistry letters.

A Discriminating Protecting Group Strategy for Alcohols and Amines

B. Ganem, L. Liotta, 1991 .

A Practical Synthesis of Isocyanates from Isonitriles: Ethyl 2-Isocyanatoacetate.

B. Ganem, H. Le, 2014, Organic syntheses; an annual publication of satisfactory methods for the preparation of organic chemicals.

Observation of noncovalent enzyme-substrate and enzyme-product complexes by ion-spray mass spectrometry

B. Ganem, J. Henion, Y. Li, 1991 .

Cytostasis induced in L1210 murine leukaemia cells by the S-adenosyl-L-methionine decarboxylase inhibitor 5'-([(Z)-4-amino-2-butenyl]methylamino)-5'-deoxyadenosine may be due to hypusine depletion.

B. Ganem, T. Byers, A. Pegg, 1992, The Biochemical journal.

Mapping of chorismate mutase and prephenate dehydrogenase domains in the Escherichia coli T-protein.

B. Ganem, D. Wilson, Shuqing Chen, 2003, European journal of biochemistry.

A new synthesis of amides and macrocyclic lactams

B. Ganem, D. B. Collum, Shen-Chu Chen, 1978 .

Evidence for covalent bonding of native hapten–protein complexes to smooth lipopolysaccharide of Brucella abortus

B. Ganem, A. Winter, V. Perera, 1984 .

Efficient preparation of enantiomerically pure cyclic aminoalditols, total synthesis of 1-deoxynojirimycin and 1-deoxymannojirimycyn

B. Ganem, R. Bernotas, 1985 .

Arene oxides in biosynthesis. On the origin of crotepoxide, senepoxide, and pipoxide

B. Ganem, G. W. Holbert, 1977 .

An improved synthesis of D-perosamine and some derivatives.

B. Ganem, M. J. Eis, 1988, Carbohydrate research.

A new method for transforming primary amines into phosphoric acid monoesters1

B. Ganem, Jiangchen Luo, 1991 .

A new synthesis of caged GABA compounds for studying GABAA receptors.

B. Ganem, G. P. Hess, Ryan W. Lewis, 2009, Bioorganic & medicinal chemistry letters.

Alkyl and cyclopropyl sugars: approaches to branched-chain D-glucofuranose derivatives☆

B. Ganem, R. Bonjouklian, 1979 .

.alpha.-Silylated vinyl ketones. New class of reagents for the annelation of ketones

B. Ganem, G. Stork, 1973 .

An efficient synthesis of substituted prolines by the selective reduction and reductive cyanation of 2-pyrrolidones

B. Ganem, Q. Xia, 2002 .

Analysis of the Stoichiometry of the T4 Gene 45 Protein by Ion Spray Mass Spectrometry

B. Ganem, J. Henion, S. Benkovic, 1994 .

Mass Spectrometric Investigations of Drug‐Receptor Interactions

B. Ganem, J. Henion, Y. Hsieh, 1993, Therapeutic drug monitoring.

Studies on heme binding in myoglobin, hemoglobin, and cytochrome c by ion spray mass spectrometry

B. Ganem, J. Henion, Y. Hsieh, 1993, Journal of the American Society for Mass Spectrometry.

Detection of Oligonucleotide Duplex Forms by Ion-Spray Mass Spectrometry.

B. Ganem, J. Henion, Yanbin Li, 1993 .

Design and synthesis of substrate analogs for the inhibition of dehydroquinate synthase

B. Ganem, N. Nikolaides, 1989 .

Glutathionyl transferase catalyzed addition of glutathione to COMC: a new hypothesis for antitumor activity.

B. Ganem, D. J. Creighton, Zhebo Ding, 2002, Organic letters.

STRUCTURE AND TOTAL SYNTHESIS OF HF-7, A NEUROACTIVE GLYCONUCLEOSIDE DISULFATE FROM THE FUNNEL-WEB SPIDER HOLOLENA CURTA

B. Ganem, J. Meinwald, G. A. Marel, 1999 .

Reduction of Secondary Carboxamides to Imines.

B. Ganem, Jun Li, D. Schedler, 1996, The Journal of organic chemistry.

From glucose to aromatics: recent developments in natural products of the shikimic acid pathway

B. Ganem, 1978 .

Studies on the Biginelli reaction: a mild and selective route to 3,4-dihydropyrimidin-2(1H)-ones via enamine intermediates

B. Ganem, J. Mabry, 2006 .

Inhibition of plant glycosidases by a D-galacturonic acid analog

B. Ganem, E. M. Blumenthal, Michael K. Tong, 1990 .

Synthesis of 2S-carboxy-3R, 4R, 5S-trihydroxypiperidine, a naturally occurring inhibitor of β-D-glucuronidase

B. Ganem, R. Bernotas, 1985 .

Shikimate-derived metabolites revised structure and total synthesis of pipoxide

B. Ganem, J. Clardy, K. Chantrapromma, 1979 .

A new approach to substituted arene oxides. Total synthesis of senepoxide and seneol

B. Ganem, L. B. Weiss, G. W. Holbert, 1978 .

The structure of ferrudiol. A highly oxidized constituent of uvaria ferruginea

B. Ganem, G. Schulte, K. Chantrapromma, 1982 .

Studies on highly oxidized cyclohexanes. Structure and absolute configuration assignments.

B. Ganem, G. Schulte, 1982 .

(3R,4R,5S)-5-acetamido-3,4-piperidinediol: a selective hexosaminidase inhibitor.

B. Ganem, R. Bernotas, 1987, Carbohydrate research.

Total syntheses of (+)-castanospermine and (+)-deoxynojirimycin

B. Ganem, R. Bernotas, 1984 .

Multiple component Fischer indole reactions

B. Ganem, Christopher A. Simoneau, 2005 .

Studies on the chemistry and reactivity of alpha-substituted ketones in isonitrile-based multicomponent reactions.

B. Ganem, Ashley M. Adams, Jason G. Polisar, 2008, The Journal of organic chemistry.

A practical and inexpensive ‘convertible’ isonitrile for use in multicomponent reactions

B. Ganem, H. Le, Lijun Fan, 2011 .

Metal-promoted variants of the Passerini reaction leading to functionalized heterocycles.

B. Ganem, Q. Xia, 2002, Organic letters.

Mechanism of sodium borohydride-cobaltous chloride reductions

B. Ganem, S. Heinzman, 1982 .

Synthetically useful reactions with metal boride and aluminide catalysts

B. Ganem, J. Osby, 1986 .

Rapid and efficient reduction of aliphatic nitro compounds to amines

B. Ganem, J. Osby, 1985 .

Studies on the mechanism of transition-metal-assisted sodium borohydride and lithium aluminum hydride reductions

B. Ganem, J. Osby, S. Heinzman, 1986 .

An exceptionally mild deprotection of phthalimides

B. Ganem, J. Osby, M. Martin, 1984 .

Lithium and potassium trialkylborohydrides. Reagents for direct reduction of .alpha.,.beta.-unsaturated carbonyl compounds to synthetically versatile enolate anions

B. Ganem, J. Fortunato, 1976 .

Conjugate reduction and reductive alkylation of .alpha.,.beta.-unsaturated cyclohexenones using potassium tri-sec-butylborohydride

B. Ganem, 1975 .

A general, highly stereoselective synthesis of amines

B. Ganem, Wrobel Jay Edward, 1982 .

Cytotoxic, antifouling bromotyramines: a synthetic study on simple marine natural products and Their analogues.

B. Ganem, D. Rittschof, R. C. Schoenfeld, 2002, Bioorganic & medicinal chemistry letters.

Advances in the chemistry of 2,3-epoxyalcohols. New methodology for contra-trans-diaxial opening and selective enediol oxidation

B. Ganem, B. Mckittrick, 1985 .

5.14 – Catalysis by Chorismate Mutases

B. Ganem, 1999 .

A new class of endoglycosidase inhibitors: studies on endocellulases

B. Ganem, L. Liotta, D. Wilson, 1989 .

Chelate selectivity in chelation-controlled allylations. A new synthesis of castanospermine and other bioactive indolizidine alkaloids

B. Ganem, H. Hamana, N. Ikota, 1987 .

An exceptionally mild deprotection of phthalimides

B. Ganem, J. Osby, M. Martin, 1984 .

Bioactive 2-oxazolines: a new approach via one-pot, four-component reaction.

B. Ganem, E. Lobkovsky, Lijun Fan, 2007, Organic letters.

Spiroannelation of enol ethers of cyclic 1,3-diketones. Simple stereospecific synthesis of .beta.-vetivone

B. Ganem, R. Danheiser, G. Stork, 1973 .

Selective fowler reductions: asymmetric total syntheses of isofagomine and other 1-azasugars from methyl nicotinate.

B. Ganem, G. Zhao, U. C. Deo, 2001, Organic letters.

Total synthesis of kukoamine A, an antihypertensive constituent of lycium chinense

B. Ganem, K. Chantrapromma, 1981 .

The chemistry of naturally occurring polyamines. A total synthesis of thermospermine

B. Ganem, K. Chantrapromma, J. McManis, 1980 .

Studies on morpholinosphingolipids: Potent inhibitors of glucosylceramide synthase

B. Ganem, N. Radin, J. Shayman, 1994 .

syn-Stereoselective Epoxidation of Allylic Ethers Using CF3CO3H.

B. Ganem, B. Mckittrick, 1986 .

Dihydropyrimidinone positive modulation of delta-subunit-containing gamma-aminobutyric acid type A receptors, including an epilepsy-linked mutant variant.

B. Ganem, Kyle P. Eagen, G. P. Hess, 2010, Biochemistry.

Chemistry of naturally occurring polyamines. 11. Unsaturated spermidine and spermine derivatives

B. Ganem, S. Nagarajan, 1987 .

Catalyzed insertion reactions of substituted α-diazoesters. A new synthesis of cis-enoates

B. Ganem, S. D. Young, N. Takamura, 1981 .

New chemistry of naturally occurring polyamines

B. Ganem, 1982 .

Synthetic Studies on Mannostatin A and Its Derivatives: A New Family of Glycoprotein Processing Inhibitors

B. Ganem, S. King, 1994 .

Multicomponent reaction design: a one-pot route to substituted di-O-acylglyceric acid amides from α-diazoketones

B. Ganem, Ashley M. Adams, Lijun Fan, 2008 .

Shikimate-derived metabolites. 10. Synthetic studies on the biosynthesis of para-aminobenzoic acid.

B. Ganem, Chia-Yu P. Teng, 1982 .

An Enantioselective Synthesis of (-)-Allosamidin by Asymmetric Desymmetrization of a Highly Functionalized meso-Epoxide.

B. Ganem, D. Kassab, 1999, The Journal of organic chemistry.

New four-component condensations leading to 2,4,5-trisubstituted oxazoles☆

B. Ganem, Qunzhao Wang, 2003 .

A general synthesis of 2-substituted-5-aminooxazoles: building blocks for multifunctional heterocycles

B. Ganem, Qunzhao Wang, Q. Xia, 2003 .

Ferric chloride in acetic anhydide. Mild and versatile reagent for the cleavage of ethers

B. Ganem, V. Small, 1974 .

syn-Selective additions to Garner aldehyde: synthesis of a potent glucosylceramide synthase inhibitor

B. Ganem, A. Husain, 2002 .

Shikimate-derived metabolites. 3. Total synthesis of senepoxide and seneol according to a biogenetic proposal

B. Ganem, G. W. Holbert, 1978 .

Total synthesis of (−)-vertinolide. A general approach to chiral tetronic acids and butenolides from allylic alcohols

B. Ganem, J. Wrobel, 1983 .

Chemistry of naturally occurring polyamines. 10. Nonmetabolizable derivatives of spermine and spermidine

B. Ganem, S. Nagarajan, 1986 .

Chemistry of naturally occurring polyamines. 9. Synthesis of spermidine and spermine photoaffinity labeling reagents

B. Ganem, S. Nagarajan, 1985 .

The chemistry of naturally occurring polyamines. 6. Efficient syntheses of N1- and N8-acetylspermidine

B. Ganem, C. Tice, 1983 .

Synthesis of cytotoxic spermidine metabolites from the soft coral

B. Ganem, K. Chantrapromma, J. McManis, 1980 .

Epoxides as alkene protecting groups. A mild and efficient deoxygenation

B. Ganem, M. Martin, 1984 .

A new protecting group for amines. Synthesis of anticapsin from L-tyrosine

B. Ganem, B. C. Laguzza, 1981 .

Unique methodology for the conjugate reduction and reductive alkylation of .alpha.,.beta.-unsaturated carboxylic esters

B. Ganem, J. Fortunato, 1975 .

Silver-assisted dimethylsulfoxide oxidations; An improved synthesis of aldehydes and ketones

B. Ganem, R. K. Boeckman, 1974 .

A new .beta.-lactam synthesis

B. Ganem, R. Wood, Alan J. Biloski, 1982 .

Asymmetric total synthesis of (-)-alpha-kainic acid using an enantioselective, metal-promoted ene cyclization.

B. Ganem, Q. Xia, Qian Xia, 2001, Organic letters.

A simple solution to the oxazole problem in virginiamycin M

B. Ganem, R. Wood, 1984 .

Virginiamycin M: absolute configuration and synthetic studes

B. Ganem, R. Wood, 1982 .

Tandem multicomponent/click reactions : synthesis of functionalized oxazoles and tetrazoles from acyl cyanides

B. Ganem, I. Clemencon, 2007 .

A three-component Fischer indole synthesis

B. Ganem, Christopher A. Simoneau, 2008, Nature Protocols.

A new approach to four- and five-component Ugi condensations starting from nitriles

B. Ganem, E. George, Christopher A. Simoneau, 2006 .

Mechanism and synthetic utility of boron trifluoride etherate promoted organolithium additions

B. Ganem, M. J. Eis, J. Wrobel, 1984 .

Total synthesis of (.+-.)-4-amino-4-deoxychorismic acid: a key intermediate in the biosynthesis of p-aminobenzoic acid and L-p-aminophenylalanine

B. Ganem, R. Bhatnagar, L. Vining, 1985 .

Shikimate-derived metabolites. 11. A total synthesis of (.+-.)-chorismic acid

B. Ganem, W. Wade, S. D. Young, 1982 .

On the mechanism of chorismate mutases: Revisiting structural requirements for catalysis

B. Ganem, C. Galopin, 1997 .

Transition-state analogue inhibitors of chorismate mutase

B. Ganem, J. Stewart, T. Clarke, 1990 .

INHIBITORS OF CARBOHYDRATE-PROCESSING ENZYMES : DESIGN AND SYNTHESIS OF SUGAR-SHAPED HETEROCYCLES

B. Ganem, 1996 .

Synthesis of (-)-3-homoshikimic acid and (-)-3-homoshikimate-3-phosphate

B. Ganem, H. Wood, 1993 .

Chapter 4 – Synthetic Studies on Pentacyclic Quassinoids

B. Ganem, 1991 .

Ready oxidation of halides to aldehydes using trimethylamine N-oxide in dimethylsulfoxide

B. Ganem, A. Godfrey, 1990 .

NEIGHBORING GROUP EFFECTS IN THE REGIOSELECTIVE CYCLIZATION OF VICINAL TRANS-1,2-BROMOHYDRINS TO EPOXIDES

B. Ganem, F. Lang, D. Kassab, 1998 .

The Mechanism of the Claisen Rearrangement: Déjà Vu All Over Again

Bruce Ganem, B. Ganem, 1996 .

The Mechanism of the Claisen Rearrangement: Deja-vu All Over Again

B. Ganem, 1996 .

Synthesis of (+)-1,5-dideoxy-1,5-imino-d-galactitol, a potent α-d-galactosidase inhibitor

B. Ganem, R. Bernotas, M. Pezzone, 1987 .

Studies on the oxidation of imino ethers

B. Ganem, Alan J. Biloski, 1983 .

Synthesis of 1-β-amino-1-deoxynojirimycins: a new family of glucosidase inhibitors

B. Ganem, S. King, H. Yoon, 1991 .

Effect of 1-epoxyalkyl-1-deoxynojirimycins on exoglucosidases

B. Ganem, L. Liotta, Jeehiun K. Lee, 1991 .

A New Class of Endoglycosidase Inhibitors. Studies on Endocellulases.

B. Ganem, L. Liotta, D. Wilson, 1989 .

Shikimate-derived metabolites. 12. Stereocontrolled total synthesis of shikimic acid and 6.beta.-deuterioshikimate

B. Ganem, V. Muralidharan, K. E. Coblens, 1982 .

One-pot synthesis of polysubstituted indoles from aliphatic nitro compounds under mild conditions.

B. Ganem, Christopher A. Simoneau, Alexis M. Strohl, 2007, Tetrahedron letters.

Conjugate addition of 1 - trialkylsilylpropynylcopper derivatives; a new synthesis of 1, 5-allenic and acetylenic olefins

B. Ganem, 1974 .

Oxidation of bicyclic oxazolines: applications to glycomimetics and novel saccharide derivatives

B. Ganem, Qunzhao Wang, M. Clark, 2002 .

D-mannonolactam amidrazone. A new mannosidase inhibitor that also inhibits the endoplasmic reticulum or cytoplasmic alpha-mannosidase.

G. Papandreou, B. Ganem, G. Kaushal, 1992, The Journal of biological chemistry.

Potent, broad-spectrum inhibition of glycosidases by an amidine derivative of D-glucose

G. Papandreou, B. Ganem, Michael K. Tong, 1990 .

Chelate Selectivity in Chelation-Controlled Allylations. A New Synthesis of Castanospermine and Other Bioactive Indolizidine Alkaloids.

B. Ganem, H. Hamana, N. Ikota, 1988 .

Studies on 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase using chorismate mutase inhibitors.

B. Ganem, R. Woodard, A. Husain, 2001, Bioorganic & medicinal chemistry letters.

A potent new class of active-site-directed glycosidase inactivators

B. Ganem, Michael K. Tong, 1988 .

BF3-etherate promoted alkylation of aziridines with organocopper reagents: a new synthesis of amines

B. Ganem, M. J. Eis, 1985 .

General synthesis of pentacyclic quassinoids

B. Ganem, N. Takamura, D. Batt, 1984 .

Masked arenes; synthesis of substituted benzenes and benzene oxides

B. Ganem, L. B. Weiss, G. W. Holbert, 1976 .

Conformational and stereochemical control of an unprecedented neighboring group participation. A new, stereospecific chloroepoxide synthesis

B. Ganem, 1976 .

A Short Homochiral Synthesis of Substituted Pyrrolidines

B. Ganem, L. Liotta, 1990 .

Reaction of COTC with glutathione: structure of the putative glyoxalase I inhibitor.

B. Ganem, D. J. Creighton, D. Hamilton, 2000, Organic letters.

Reductive deoxygenation by Cp2ZrHCl: Selective formation of imines via zirconation/hydrozirconation of amides

B. Ganem, A. Godfrey, D. Schedler, 1993 .

Reductive deoxygenation using hydridozirconium enolates: A new synthesis of α,β-unsaturated esters

B. Ganem, A. Godfrey, 1992 .

3‐Trimethylsilyl‐3‐Buten‐2‐one: A Michael acceptor

B. Ganem, R. K. Boeckman, D. Blum, 2003 .

Phosphonate analogs of chorismic acid: synthesis and evaluation as mechanism-based inactivators of chorismate mutase

B. Ganem, H. Wood, H. Buser, 1992 .

Improved Oxidation of Amines with Dibenzoyl Peroxide

B. Ganem, Alan J. Biloski, 1983 .

Shikimate-derived metabolites. 2. Synthesis of a bacterial natural product illustrating a concerted syn-SN2' reaction

B. Ganem, N. Ikota, 1978 .

Detection of noncovalent receptor-ligand complexes by mass spectrometry

B. Ganem, J. Henion, Y. Li, 1991 .

Pseudoceratidine, a marine natural product with antifouling activity: Synthetic and biological studies

B. Ganem, D. Rittschof, W. Kinney, 1998 .

Synthesis and evaluation of multisubstrate bicyclic pyrimidine nucleoside inhibitors of human thymidine phosphorylase.

B. Ganem, D. Shaw, Weiru Wang, 2006, Journal of medicinal chemistry.

Kukoamine A and other hydrophobic acylpolyamines: potent and selective inhibitors of Crithidia fasciculata trypanothione reductase.

P. Karplus, B. Ganem, S. Savvides, 1995, The Biochemical journal.

Improved methods for the side-chain degradation of lanosterol. The synthesis of 4,4,14alpha-trimethyl-5alpha-pregn-8-en-20-one derivatives.

B. Ganem, M. Kellogg, 1974, The Journal of organic chemistry.

Characterization of benzodiazepine "combinatorial" chemical libraries by on-line immunoaffinity extraction, coupled column HPLC-ion spray mass spectrometry-tandem mass spectrometry.

B. Ganem, J. Henion, M. Nedved, 1996, Analytical chemistry.

MECHANISM AND SYNTHETIC UTILITY OF BORON TRIFLUORIDE ETHERATE-PROMOTED ORGANOLITHIUM ADDITIONS

B. Ganem, M. J. Eis, J. Wrobel, 1984 .

New chemistry of diazoesters from thermal rearrangement of n-alkyl-n-nitrosoamides

B. Ganem, A. Godfrey, N. Nikolaides, 1990 .

New Chemistry of Diazoesters from Thermal Rearrangement of N-Alkyl-N- nitrosoamides.

B. Ganem, A. Godfrey, N. Nikolaides, 1991 .

New syntheses of alkenes and alkynes from amines

B. Ganem, A. Godfrey, 1990 .

New chemistry of amines. 2. A convenient synthesis of phosphotriesters from phosphoramidates

B. Ganem, N. Nikolaides, 1990 .

An improved procedure for the conversion of amines to alcohols at low temperature

B. Ganem, N. Nikolaides, 1989 .

Mechanism of the glutathione transferase-catalyzed conversion of antitumor 2-crotonyloxymethyl-2-cycloalkenones to GSH adducts.

B. Ganem, K. Houk, B. Mannervik, 2003, Journal of the American Chemical Society.

A new oxidation of aldehydes to carboxylic acids

B. Ganem, R. Heggs, D. Schwartz, 1980 .

Reversing the action of noncompetitive inhibitors (MK-801 and cocaine) on a protein (nicotinic acetylcholine receptor)-mediated reaction.

B. Ganem, H. Ulrich, F. Carroll, 2003, Biochemistry.

A new family of five-carbon iminoalditols which are potent glycosidase inhibitors

G. Papandreou, B. Ganem, R. Bernotas, 1990 .

A New Family of Five-Carbon Iminoalditols which are Potent Glycosidase Inhibitors.

G. Papandreou, B. Ganem, R. Bernotas, 1991 .

Enantioselective synthesis of mannostatin A: a new glycoprotein processing inhibitor

B. Ganem, S. King, 1991 .

Polyhydroxylated aziridinylcyclopentanes as glycomimetics: a new competitive inhibitor of α-mannosidase

B. Ganem, J. Lumb, R. C. Schoenfeld, 2001 .

Mimicking the glucosidase transition state : shape/charge considerations

G. Papandreou, B. Ganem, 1991 .

GUANIDINE ANALOGS OF A DEOXYSUGAR

B. Ganem, A. Chan, 1995 .

Heterocyclic routes to polysubstituted cyclopentanes: Molecular modelling of electrophilic additions to di- and trisubstituted cyclopentenes

B. Ganem, C. Wilcox, J. Nichols, 1996 .

Synthesis of 1,4,6-Trideoxy-1,4-imino-D-mannitol: a potent α-mannosidase inhibitor

B. Ganem, M. J. Eis, C. J. Rule, 1985 .

Synthesis of Methyl 5-(N-Benzoyl-N- methylamino)-2-methylpenta-2,4-dienoate by Ring-Opening Acylation of an N-Alkyltetrahydropyridine.

B. Ganem, Guohua Zhao, 1997, The Journal of organic chemistry.

Enantioselective Synthesis of Mannostatin A: A New Glycoprotein Processing Inhibitor.

B. Ganem, S. King, 1991 .

Polyhydroxylated Aziridinylcyclopentanes as Glycomimetics: A New Competitive Inhibitor of α‐Mannosidase.

B. Ganem, J. Lumb, R. C. Schoenfeld, 2002 .

Amidrazone analogues of D-ribofuranose as transition-state inhibitors of nucleoside hydrolase.

B. Ganem, V. Schramm, B. Horenstein, 1994, Biochemistry.

Guanidine Anologues of a Deoxysugar.

B. Ganem, A. Chan, 1995 .

A selective inhibitor of Escherichia coli prephenate dehydratase.

B. Ganem, D. Wilson, A. Husain, 2001, Bioorganic & medicinal chemistry letters.

Total synthesis of (±)-allosamizoline from a symmetric trisubstituted cyclopentene

B. Ganem, B. K. Goering, 1994 .

An improved synthesis of methyl 2,3-anhydro-α-d-lyxofuranoside

B. Ganem, J. R. Rasmussen, M. Martin, 1983 .

Total Synthesis of (.+-.)-Allosamizoline from a Symmetric Trisubstituted Cyclopentene.

B. Ganem, B. K. Goering, 2010 .

Total synthesis of gentiocrucine, an unusual alkaloid containing a stable primary enamide

B. Ganem, 1976 .

A REGIOSELECTIVE, CHEMOENZYMATIC SYNTHESIS OF SUCROSE-1 '-METHACRYLATE

B. Ganem, A. Chan, 1993 .

Studies on the synthesis of substituted phenanthrenoids

B. Ganem, A. Leed, S. Boettger, 1980 .

Short chemical synthesis of (-)-chorismic acid from (-)-shikimic acid

B. Ganem, H. Wood, 1990 .

On the structure of naturally-occurring (+)-methyl 3,4-anhydroshikimate

B. Ganem, H. Wood, 1989 .

Short Chemical Synthesis of (-)-Chorismic Acid from (-)-Shikimic Acid.

B. Ganem, H. Wood, 1991 .

On the Structure of Naturally‐Occurring (+)‐Methyl 3,4‐Anhydroshikimate.

B. Ganem, H. Wood, 1990 .

Shikimate-derived metabolites. 14.1 chiral synthesis of 5-enolpyruvyl-shikimate-3-phosphate

B. Ganem, Chia-Yu P. Teng, Y. Yukimoto, 1985 .

Studies on the synthesis of amidoximes from nitroalkanes.

B. Ganem, H. Le, G. Sanguineti, 2011, Tetrahedron.

An approach to the synthesis of lycorine

B. Ganem, 1971 .

Enantioselective synthesis of (−)-methyl 5-lactylshikimate lactone

B. Ganem, H. Wood, V. Muralidharan, 1990 .

SHIKIMATE-DERIVED METABOLITES. 14. CHIRAL SYNTHESIS OF 5-ENOLPYRUVYLSHIKIMATE-3-PHOSPHATE

B. Ganem, Chia-Yu P. Teng, Y. Yukimoto, 1985 .

Shikimate-derived metabolites. 13. A key intermediate in the biosynthesis of anthranilate from chorismate

B. Ganem, Chia-Yu P. Teng, 1984 .

Synthesis of cyathiformines A-C: Unusual fungal metabolites derived from chorismic acid

B. Ganem, R. Meier, 1994 .

Identification of two functionally different classes of exocellulases.

B. Ganem, D. Wilson, Y. Hsieh, 1996, Biochemistry.

Biological spin labels as organic reagents. Oxidation of alcohols to carbonyl compounds using nitroxyls

B. Ganem, 1975 .

Chorismate Mutase-Prephenate Dehydratase from Escherichia coli

Shenmin Zhang, B. Ganem, J. Clardy, 1998, The Journal of Biological Chemistry.

Charge is the major discriminating factor for glutathione reductase versus trypanothione reductase inhibitors.

P. Karplus, B. Ganem, S. Savvides, 1996, Bioorganic & medicinal chemistry.

Probing the overlap of chorismate mutase and prephenate dehydrogenase sites in the escherichia coli T-protein: a dehydrogenase-selective inhibitor.

B. Ganem, D. Wilson, Shuqing Chen, 2002, Bioorganic & medicinal chemistry letters.

Three-Component Condensation Leading to β-Amino Acid Diamides: Convergent Assembly of β-Peptide Analogues

B. Ganem, U. Peters, Jennifer M. Oaksmith, 2004 .

Amidrazone and Amidoxime Inhibitors of Squalene Hopene Cyclase.

B. Ganem, G. Prestwich, Y. Zheng, 1999, The Journal of organic chemistry.

A new synthesis of the glyoxalase-I inhibitor COTC

B. Ganem, H. Wood, C. Huntley, 2000 .

Going gently into flight: analyzing noncovalent interactions by mass spectrometry.

B. Ganem, J. Henion, 2003, Bioorganic & medicinal chemistry.

Studies of non-covalent interactions of actinomycin D with single-stranded oligodeoxynucleotides by ion spray mass spectrometry and tandem mass spectrometry.

B. Ganem, J. Henion, Y. Hsieh, 1994, Biological mass spectrometry.

3‐Trimethylsilyl‐3‐Buten‐2‐One as Michael Acceptor for Conjugate Addition‐Annelation: cis‐4,4a,5,6,7,8‐Hexahydro‐4a,5‐Dimethyl‐2(3H)‐Naphthalenone

B. Ganem, R. K. Boeckman, D. Blum, 2003 .

Novel multisubstrate inhibitors of mammalian purine nucleoside phosphorylase.

B. Ganem, Weiru Wang, S. Ealick, 2005, Acta crystallographica. Section D, Biological crystallography.

A pharmacokinetic-pharmacodynamic modelling of the antihistaminic (H1) effects of cetirizine.

B. Ganem, S. Urien, J. Tillement, 1999, International journal of clinical pharmacology and therapeutics.

A theoretical study of the chorismate synthase reaction.

B. Ganem, R. D. Bach, O. Dmitrenko, 2001, Organic letters.

Mild oxidation of tosylmethylisocyanide to tosylmethylisocyanate: utility in synthetic and medicinal chemistry.

B. Ganem, H. Le, 2014, Tetrahedron letters.

Paclitaxel from Primary Taxanes: A Perspective on Creative Invention in Organozirconium Chemistry

B. Ganem, R. Franke, 2007 .

Paclitaxel from primary taxanes: a perspective on creative invention in organozirconium chemistry.

Bruce Ganem, B. Ganem, Roland R Franke, 2007, The Journal of organic chemistry.

Stereoselective fragmentation of a tricyclic diester leading to a potent chorismate mutase transition state inhibitor

B. Ganem, J. Stewart, T. Clarke, 1987 .

Synthesis of ceratinamine and moloka'iamine: Antifouling agents from the marine sponge Pseudoceratina purpurea

B. Ganem, R. C. Schoenfeld, 1998 .

Cytotoxic, antifouling bromotyramines: a synthetic study on simple marine natural products and Their analogues.

B. Ganem, D. Rittschof, R. C. Schoenfeld, 2002, Bioorganic & medicinal chemistry letters.

Total synthesis of mololipids: a new series of anti-HIV Moloka'iamine derivatives.

B. Ganem, J. Fantini, J. Lumb, 2000, Bioorganic & Medicinal Chemistry Letters.

Synthesis of Ceratinamine and Moloka′iamine: Antifouling Agents from the Marine Sponge Pseudoceratina purpurea.

B. Ganem, R. C. Schoenfeld, 1998 .

Total Synthesis of Mololipids: A New Series of Anti‐HIV Moloka′iamine Derivatives.

B. Ganem, J. Fantini, J. Lumb, 2001 .

Synthesis of the antifouling polyamine pseudoceratidine and its analogs: Factors influencing biocidal activity

B. Ganem, D. Kassab, J. Ponasik, 1996 .

U-3'-BCIP: a chromogenic substrate for the detection of RNase A in recombinant DNA expression systems

Harold A. Scheraga, M. P. Weiner, M. R. Witmer, 1991, Nucleic Acids Res..

Synthesis of a COMC–estradiol conjugate for targeted, tissue-selective cancer chemotherapy

B. Ganem, Jennifer M. Oaksmith, 2009 .

Molecular basis of the antitumor activities of 2-crotonyloxymethyl-2-cycloalkenones.

B. Ganem, J. Eiseman, E. Joseph, 2003, Journal of Medicinal Chemistry.

Selective inhibition of MCF-7(piGST) breast tumors using glutathione transferase-derived 2-methylene-cycloalkenones.

B. Ganem, J. Eiseman, E. Joseph, 2005, Journal of medicinal chemistry.

Selenium in synthesis. Conjugated vinylic ethers, esters, and halides from .alpha.-hetero-substituted selenides

B. Ganem, N. Ikota, 1978 .

Strategies for innovation in multicomponent reaction design.

B. Ganem, 2009, Accounts of chemical research.

Trypanosomal nucleoside hydrolase. Resonance Raman spectroscopy of a transition-state inhibitor complex.

B. Ganem, V. Schramm, R. Callender, 1996, Biochemistry.

Design and Synthesis of D-Ribofuranoamidrazones as Inhibitors of Nucleoside Processing Enzymes

B. Ganem, V. Schramm, B. Horenstein, 1995 .