D. Zamanillo

发表

Importance of AMPA receptors for hippocampal synaptic plasticity but not for spatial learning.

J. Lübke, M. Frotscher, B. Sakmann, 1999, Science.

A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins

Michel Morange, John Rouse, Tim Hunt, 1994, Cell.

5-HT7 receptor activation inhibits mechanical hypersensitivity secondary to capsaicin sensitization in mice

D. Zamanillo, H. Buschmann, M. Hamon, 2009, PAIN.

Supraspinal and Peripheral, but Not Intrathecal, σ1R Blockade by S1RA Enhances Morphine Antinociception

D. Zamanillo, J. Vela, M. Merlos, 2019, Front. Pharmacol..

Sigma-1 receptors are essential for capsaicin-induced mechanical hypersensitivity: Studies with selective sigma-1 ligands and sigma-1 knockout mice

D. Zamanillo, J. Entrena, J. Baeyens, 2009, PAIN®.

Synthesis and biological evaluation of the 1-arylpyrazole class of σ(1) receptor antagonists: identification of 4-{2-[5-methyl-1-(naphthalen-2-yl)-1H-pyrazol-3-yloxy]ethyl}morpholine (S1RA, E-52862).

D. Zamanillo, C. Laggner, J. Holenz, 2012, Journal of medicinal chemistry.

A Medicinal‐Chemistry‐Guided Approach to Selective and Druglike Sigma 1 Ligands

D. Zamanillo, J. Holenz, H. Buschmann, 2006, ChemMedChem.

Up-regulation of sigma1 receptor mRNA in rat brain by a putative atypical antipsychotic and sigma receptor ligand

D. Zamanillo, X. Guitart, A. Farré, 2000, Neuroscience Letters.

Blockade of the Sigma-1 Receptor Relieves Cognitive and Emotional Impairments Associated to Chronic Osteoarthritis Pain

D. Zamanillo, R. Maldonado, M. Merlos, 2019, Front. Pharmacol..

Neuroprotective Effects of Sigma 1 Receptor Ligands on Motoneuron Death after Spinal Root Injury in Mice

D. Zamanillo, J. Vela, M. Merlos, 2021, International journal of molecular sciences.

Assessment of 5-HT7 Receptor Agonists Selectivity Using Nociceptive and Thermoregulation Tests in Knockout versus Wild-Type Mice

D. Zamanillo, M. Hamon, L. Romero, 2012, Advances in pharmacological sciences.

Assessment of 5-HT 7 Receptor Agonists Selectivity Using Nociceptive and Thermoregulation Tests in Knockout versusWild-TypeMice

D. Zamanillo, M. Hamon, L. Romero, 2014 .

Potentiation of morphine analgesia by adjuvant activation of 5-HT7 receptors.

D. Zamanillo, L. Romero, A. Brenchat, 2011, Journal of pharmacological sciences.

Sigma-1 receptor modulates neuroinflammation associated with mechanical hypersensitivity and opioid tolerance in a mouse model of osteoarthritis pain Running title: σ1R on mechanical pain and opioid tolerance during osteoarthritis

D. Zamanillo, R. Maldonado, M. Merlos, 2019 .

Role of peripheral versus spinal 5‐HT7 receptors in the modulation of pain undersensitizing conditions

D. Zamanillo, M. Hamon, L. Romero, 2012, European journal of pain.

Evaluation of formalin-induced pain behavior and glutamate release in the spinal dorsal horn using in vivo microdialysis in conscious rats.

D. Zamanillo, J. Vela, M. Merlos, 2012, Journal of pharmacological sciences.

Operant self‐administration of a sigma ligand improves nociceptive and emotional manifestations of neuropathic pain

D. Zamanillo, R. Maldonado, J. Vela, 2013, European journal of pain.

Sigma 1 receptor: a new therapeutic target for pain.

D. Zamanillo, L. Romero, J. Vela, 2013, European journal of pharmacology.

Bispecific sigma-1 receptor antagonism and mu-opioid receptor partial agonism: WLB-73502, an analgesic with improved efficacy and safety profile compared to strong opioids

D. Zamanillo, X. Codony, L. Romero, 2022, Acta pharmaceutica Sinica. B.

Administration of a co‐crystal of tramadol and celecoxib in a 1:1 molecular ratio produces synergistic antinociceptive effects in a postoperative pain model in rats

D. Zamanillo, X. Codony, L. Romero, 2018, European journal of pharmacology.

Pharmacological properties of S1RA, a new sigma‐1 receptor antagonist that inhibits neuropathic pain and activity‐induced spinal sensitization

D. Zamanillo, J. Giraldo, J. Lopez-Garcia, 2012, British journal of pharmacology.

Potentiation of morphine-induced mechanical antinociception by σ1 receptor inhibition: Role of peripheral σ1 receptors

D. Zamanillo, J. Entrena, J. Baeyens, 2013, Neuropharmacology.

Sigma-1 receptor and inflammatory pain

D. Zamanillo, E. J. Cobos, G. Gris, 2015, Inflammation Research.

Sigma-1 receptor antagonism as opioid adjuvant strategy: enhancement of opioid antinociception without increasing adverse effects.

S. A. Bura, D. Zamanillo, X. Codony, 2013, European journal of pharmacology.

Effects of the selective sigma‐1 receptor antagonist S1RA on formalin‐induced pain behavior and neurotransmitter release in the spinal cord in rats

D. Zamanillo, J. Vela, M. Merlos, 2014, Journal of neurochemistry.

The selective sigma-1 receptor antagonist E-52862 attenuates neuropathic pain of different aetiology in rats

D. Zamanillo, J. Vela, M. Merlos, 2016, Scientific Reports.

Comprehensive Preclinical Assessment of Sensory, Functional, Motivational-Affective, and Neurochemical Outcomes in Neuropathic Pain: The Case of the Sigma-1 Receptor.

D. Zamanillo, L. Romero, J. Vela, 2022, ACS pharmacology & translational science.

Sigma‐1 receptor modulates neuroinflammation associated with mechanical hypersensitivity and opioid tolerance in a mouse model of osteoarthritis pain

D. Zamanillo, R. Maldonado, A. Dickenson, 2019, British journal of pharmacology.

Generation and phenotypic analysis of sigma receptor type I (σ1) knockout mice

D. Zamanillo, X. Codony, L. Montoliu, 2003 .

Somatic Accumulation of GluA1-AMPA Receptors Leads to Selective Cognitive Impairments in Mice

J. Rawlins, N. Burnashev, D. Zamanillo, 2018, Front. Mol. Neurosci..

Selective sigma-1 (sigma1) receptor antagonists: emerging target for the treatment of neuropathic pain.

D. Zamanillo, J. Díaz, R. Maldonado, 2009, Central nervous system agents in medicinal chemistry.

Repeated Sigma-1 Receptor Antagonist MR309 Administration Modulates Central Neuropathic Pain Development After Spinal Cord Injury in Mice

D. Zamanillo, X. Codony, M. Merlos, 2019, Front. Pharmacol..

Sigma 1 Receptor Chaperone: Pharmacology and Therapeutic Perspectives

D. Zamanillo, L. Romero, J. Vela, 2012 .

Role of sigma-1 receptors in paclitaxel-induced neuropathic pain in mice.

D. Zamanillo, J. Entrena, J. Baeyens, 2012, The journal of pain : official journal of the American Pain Society.

Sigma-1 receptor and inflammatory pain

D. Zamanillo, E. J. Cobos, G. Gris, 2015, Inflammation Research.

Modulation by Sigma-1 Receptor of Morphine Analgesia and Tolerance: Nociceptive Pain, Tactile Allodynia and Grip Strength Deficits During Joint Inflammation

D. Zamanillo, M. A. Tejada, E. J. Cobos, 2019, Front. Pharmacol..

Sigma-1 Receptor and Pain.

D. Zamanillo, L. Romero, J. Vela, 2017, Handbook of experimental pharmacology.

Effects of centrally acting analgesics on spinal segmental reflexes and wind‐up

D. Zamanillo, J. Lopez-Garcia, J. Vela, 2015, European journal of pain.

S1RA, a selective sigma-1 receptor antagonist, inhibits inflammatory pain in the carrageenan and complete Freund’s adjuvant models in mice

D. Zamanillo, J. Vela, M. Merlos, 2014, Behavioural pharmacology.

341 POTENTIATION OF MORPHINE ANALGESIA BUT INHIBITION OF ITS REWARDING EFFECTS FOLLOWING COADMINISTRATION OF A NEW SELECTIVE SIGMA‐1 RECEPTOR ANTAGONIST

D. Zamanillo, R. Maldonado, L. Romero, 2009 .

Molecular Cloning of α1d‐Adrenergic Receptor and Tissue Distribution of Three α1‐Adrenergic Receptor Subtypes in Mouse

D. Zamanillo, E. Casanova, A. Alonso-Llamazares, 1995 .

Molecular cloning of alpha 1d-adrenergic receptor and tissue distribution of three alpha 1-adrenergic receptor subtypes in mouse.

D. Zamanillo, E. Casanova, A. Alonso-Llamazares, 1995, Journal of neurochemistry.

The calcium-sensitive Sigma-1 receptor prevents cannabinoids from provoking glutamate NMDA receptor hypofunction: implications in antinociception and psychotic diseases.

D. Zamanillo, M. Rodríguez-Muñoz, P. Sánchez-Blázquez, 2014, The international journal of neuropsychopharmacology.

Regulation of Ionotropic Glutamate Receptor Subunits in Different Rat Brain Areas by a Preferential Sigma1 Receptor Ligand and Potential Atypical Antipsychotic

D. Zamanillo, X. Guitart, A. Farré, 2000, Neuropsychopharmacology.

AMPA receptor GluR2, but not GluR1, subunit deletion impairs emotional response conditioning in mice.

D. Zamanillo, D. Stephens, L. Mayne, 2006, Behavioral neuroscience.

Pharmacological sensitivity of reflexive and nonreflexive outcomes as a correlate of the sensory and affective responses to visceral pain in mice

D. Zamanillo, L. Romero, J. Vela, 2017, Scientific Reports.

Phosphorylation of the Third Intracellular Loop of the Mouse α 1b-Adrenergic Receptor by cAMP-dependent Protein Kinase

D. Zamanillo, E. Casanova, A. Alonso-Llamazares, 1997, Brain Research Bulletin.

Identification of a cyclic adenosine 3′,5′-monophosphate-dependent protein kinase phosphorylation site in the carboxy terminal tail of human D1 dopamine receptor

D. Zamanillo, E. Casanova, A. Alonso-Llamazares, 1995, Neuroscience Letters.

Predicting the antinociceptive efficacy of σ(1) receptor ligands by a novel receptor fluorescence resonance energy transfer (FRET) based biosensor.

D. Zamanillo, F. Ciruela, J. Vela, 2014, Journal of medicinal chemistry.

Immunohistochemical localization of the σ1-receptor in oligodendrocytes in the rat central nervous system

D. Zamanillo, X. Guitart, J. Vela, 2003, Brain Research.

Generation and phenotypic analysis of sigma receptor type I (sigma 1) knockout mice.

D. Zamanillo, X. Codony, L. Montoliu, 2003, The European journal of neuroscience.

Immunohistochemical localization of the sigma1-receptor in oligodendrocytes in the rat central nervous system.

D. Zamanillo, X. Guitart, J. Vela, 2003, Brain research.

Morphine-Induced Dependence and Sensitization Are Altered in Mice Deficient in AMPA-Type Glutamate Receptor-A Subunits

T Seppälä, P. Seeburg, D. Zamanillo, 2001, The Journal of Neuroscience.

The AMPA receptor subunit GluR-B in its Q/R site-unedited form is not essential for brain development and function.

N. Burnashev, P. Seeburg, D. Zamanillo, 1998, Proceedings of the National Academy of Sciences of the United States of America.

AMPA-Receptor GluR1 Subunits are Involved in the Control Over Behavior by Cocaine-Paired Cues

D. Zamanillo, D. Stephens, N. Becker, 2007, Neuropsychopharmacology.

Pharmacological sensitivity of reflexive and nonreflexive outcomes as a correlate of the sensory and affective responses to visceral pain in mice

D. Zamanillo, L. Romero, J. Vela, 2017, Scientific Reports.

Changes in saccharin preference behavior as a primary outcome to evaluate pain and analgesia in acetic acid-induced visceral pain in mice

D. Zamanillo, J. Vela, M. Merlos, 2015, Journal of pain research.

Developmental profile of kainate receptor subunit KA1 revealed by Cre expression in YAC transgenic mice

P. Seeburg, D. Zamanillo, R. Sprengel, 2000, Brain Research.

Identification of a long huntingtin mRNA transcript in mouse brain

D. Zamanillo, E. Casanova, A. Alonso-Llamazares, 1996, Brain Research.

Fibroblast growth factor‐2 is selectively modulated in the rat brain by E‐5842, a preferential sigma‐1 receptor ligand and putative atypical antipsychotic

D. Zamanillo, X. Guitart, A. Farré, 2001, The European journal of neuroscience.

Resilience to Pain-Related Depression in σ1 Receptor Knockout Mice Is Associated with the Reversal of Pain-Induced Brain Changes in Affect-Related Genes.

D. Zamanillo, A. Carceller, E. Portillo-Salido, 2023, ACS chemical neuroscience.

Differential expression of the α1C adrenergic receptor subtype in rat tissues

D. Zamanillo, A. Alonso-Llamazares, M. Chinchetru, 1993 .