G. Borgstahl

发表

Improved three-dimensional growth of manganese superoxide dismutase crystals on the International Space Station.

A. Vahedi-Faridi, J. Porta, G. Borgstahl, 2003, Acta crystallographica. Section D, Biological crystallography.

X-ray structure of Na-ASP-2, a pathogenesis-related-1 protein from the nematode parasite, Necator americanus, and a vaccine antigen for human hookworm infection.

G. Borgstahl, A. Loukas, P. Hotez, 2005, Journal of molecular biology.

Tracking reflections through cryogenic cooling with topography

R. Pahl, Jeffrey J. Lovelace, Keith Brister, 2006 .

Macromolecular crystal quality.

G. Borgstahl, H. Bellamy, E. Snell, 2013, Methods in enzymology.

Recurrent activating mutations of CD28 in peripheral T-cell lymphomas

L. Staudt, A. Rosenwald, W. Chan, 2016, Leukemia.

Structure of the full-length human RPA14/32 complex gives insights into the mechanism of DNA binding and complex formation.

G. Borgstahl, E. Snell, M. Wold, 2007, Journal of molecular biology.

Human mitochondrial manganese superoxide dismutase polymorphic variant Ile58Thr reduces activity by destabilizing the tetrameric interface.

M. Boissinot, G. Borgstahl, J. Tainer, 1996, Biochemistry.

Bromelain inhibits SARS‐CoV‐2 infection via targeting ACE‐2, TMPRSS2, and spike protein

Nicholas Y. Palermo, M. J. Broadhurst, G. Borgstahl, 2021, Clinical and translational medicine.

Human RAD52 protein has extreme thermal stability.

G. Borgstahl, R. A. Flowers Ii, W. Ranatunga, 2001, Biochemistry.

Changes to crystals of Escherichia coli beta-galactosidase during room-temperature/low-temperature cycling and their relation to cryo-annealing.

B. Matthews, G. Borgstahl, H. Bellamy, 2007, Acta crystallographica. Section D, Biological crystallography.

Aperiodic order coming of age: from inorganic materials to dynamic protein superstructures.

G. Borgstahl, P. Thiel, A. Goldman, 2019, Acta crystallographica. Section A, Foundations and advances.

Redox manipulation of the manganese metal in human manganese superoxide dismutase for neutron diffraction

G. Borgstahl, K. Weiss, L. Coates, 2018, Acta crystallographica. Section F, Structural biology communications.

Stabilization of a G-Quadruplex from Unfolding by Replication Protein A Using Potassium and the Porphyrin TMPyP4

G. Borgstahl, Fabien Kieken, L. Marky, 2011, Journal of nucleic acids.

Analysis of the human replication protein A:Rad52 complex: evidence for crosstalk between RPA32, RPA70, Rad52 and DNA.

G. Borgstahl, M. Wold, K. Dhar, 2002, Journal of molecular biology.

Small-molecule IKKβ activation modulator (IKAM) targets MAP3K1 and inhibits pancreatic tumor growth

Ayrianne J. Crawford, G. Borgstahl, M. Hollingsworth, 2022, Proceedings of the National Academy of Sciences of the United States of America.

Oncogenic Signaling by Leukemia-Associated Mutant Cbl Proteins.

G. Borgstahl, V. Band, H. Band, 2012, Biochemistry and analytical biochemistry : current research.

A Review of the Catalytic Mechanism of Human Manganese Superoxide Dismutase

G. Borgstahl, J. Azadmanesh, 2018, Antioxidants.

Peptide truncation leads to a twist and an unusual increase in affinity for casitas B-lineage lymphoma tyrosine kinase binding domain.

Nicholas Y. Palermo, Eric A. Kumar, G. Borgstahl, 2012, Journal of medicinal chemistry.

The human ITPA polymorphic variant P32T is destabilized by the unpacking of the hydrophobic core.

G. Borgstahl, L. Marky, Y. Pavlov, 2013, Journal of structural biology.

Replication Protein A Phosphorylation Facilitates RAD52-Dependent Homologous Recombination in BRCA-Deficient Cells

G. Borgstahl, S. Powell, Rohini Roy, 2021, Molecular and cellular biology.

Human RAD52 Exhibits Two Modes of Self-association*

G. Borgstahl, K. Knight, A. Forget, 2001, The Journal of Biological Chemistry.

The structure of caseinolytic protease subunit ClpP2 reveals a functional model of the caseinolytic protease system from Chlamydia trachomatis

G. Borgstahl, A. Artigues, M. Conda-Sheridan, 2022, The Journal of biological chemistry.

Cu, Zn and Mn superoxide dismutaes: Crystal structures, mutants, and function

G. Borgstahl, J. Tainer, E. Getzoff, 1993 .

Cu, Zn and Mn superoxide dismutases; Crystal structures, mutants, and function

G. Borgstahl, J. Tainer, E. Getzoff, 1993 .

Cryo-trapping the six-coordinate, distorted-octahedral active site of manganese superoxide dismutase.

G. Borgstahl, E. Snell, M. Pokross, 2000, Journal of molecular biology.

The structure of human mitochondrial manganese superoxide dismutase reveals a novel tetrameric interface of two 4-helix bundles

G. Borgstahl, J. Tainer, M. Hickey, 1992, Cell.

Direct detection of coupled proton and electron transfers in human manganese superoxide dismutase

G. Borgstahl, K. Weiss, L. Coates, 2020, Nature Communications.

Preliminary neutron diffraction analysis of challenging human manganese superoxide dismutase crystals

G. Borgstahl, K. Weiss, L. Coates, 2017, Acta crystallographica. Section F, Structural biology communications.

Holocarboxylase synthetase is a chromatin protein and interacts directly with histone H3 to mediate biotinylation of K9 and K18.

G. Borgstahl, J. Zempleni, Y. Hassan, 2011, The Journal of nutritional biochemistry.

Superoxide Dismutases (SODs) and SOD Mimetics

G. Borgstahl, R. Oberley-Deegan, 2018, Antioxidants.

Protein crystals can be incommensurately modulated

G. Borgstahl, C. Schutt, Kartik Narayan, 2008 .

Biophysical characterization and modeling of human Ecdysoneless (ECD) protein supports a scaffolding function

Nicholas P. Schafer, G. Borgstahl, N. Schafer, 2016, AIMS biophysics.

Bromelain Inhibits SARS-CoV-2 Infection in VeroE6 Cells

M. J. Broadhurst, G. Borgstahl, N. Mishra, 2020, bioRxiv.

Structure of a Protein Photocycle Intermediate by Millisecond Time-Resolved Crystallography

Wilfried Schildkamp, Elizabeth D. Getzoff, Keith Moffat, 1997, Science.

1.4 A structure of photoactive yellow protein, a cytosolic photoreceptor: unusual fold, active site, and chromophore.

G. Borgstahl, E. Getzoff, D. Williams, 1995, Biochemistry.

Ethylammonium nitrate: a protein crystallization reagent.

G. Borgstahl, C. Summers, R. A. Flowers, 1999, Acta crystallographica. Section D, Biological crystallography.

The structure and function of replication protein A in DNA replication.

G. Borgstahl, A. Prakash, Aishwarya Prakash, 2012, Sub-cellular biochemistry.

Identification of the DNA-Binding Domains of Human Replication Protein A That Recognize G-Quadruplex DNA

G. Borgstahl, M. Ouellette, L. Marky, 2011, Journal of nucleic acids.

ITPA (inosine triphosphate pyrophosphatase): from surveillance of nucleotide pools to human disease and pharmacogenetics.

G. Borgstahl, Y. Pavlov, P. Simone, 2013, Mutation research.

Functional study of the P32T ITPA variant associated with drug sensitivity in humans.

G. Borgstahl, L. Marky, C. Frahm, 2009, Journal of molecular biology.

Selective killing of homologous recombination-deficient cancer cell lines by inhibitors of the RPA:RAD52 protein-protein interaction

G. Borgstahl, Sandeep Rana, J. Lovelace, 2021, PloS one.

Complete chemical structure of photoactive yellow protein: novel thioester-linked 4-hydroxycinnamyl chromophore and photocycle chemistry.

M. Boissinot, G. Borgstahl, E. Getzoff, 1994, Biochemistry.

Replication Protein A (RPA) Hampers the Processive Action of APOBEC3G Cytosine Deaminase on Single-Stranded DNA

G. Borgstahl, I. Rogozin, I. Waisertreiger, 2011, PloS one.

Protein tyrosine kinase regulation by ubiquitination: critical roles of Cbl-family ubiquitin ligases.

Lin Dong, Nicholas Y. Palermo, G. Borgstahl, 2013, Biochimica et biophysica acta.

BH3-only proteins target BCL-xL/MCL-1, not BAX/BAK, to initiate apoptosis

G. Borgstahl, W. Zhou, Xu Luo, 2019, Cell Research.

The OB-fold domain 1 of human POT1 recognizes both telomeric and non-telomeric DNA motifs.

G. Borgstahl, Ying Yan, M. Ouellette, 2015, Biochimie.

Role of water in aging of human butyrylcholinesterase inhibited by echothiophate: the crystal structure suggests two alternative mechanisms of aging.

Patrick Masson, G. Borgstahl, P. Masson, 2005, Biochemistry.

Substrate-analog binding and electrostatic surfaces of human manganese superoxide dismutase.

G. Borgstahl, J. Azadmanesh, Scott R. Trickel, 2017, Journal of structural biology.

Human Replication Protein A−Rad52−Single-Stranded DNA Complex: Stoichiometry and Evidence for Strand Transfer Regulation by Phosphorylation†

Carol Kolar, Gloria E. O. Borgstahl, Xiaoyi Deng, 2009, Biochemistry.

Understanding the Role of Replication Protein A and RAD52 in Breast Cancer

G. Borgstahl, 2002 .

Dynamic light-scattering analysis of full-length human RPA14/32 dimer: purification, crystallization and self-association.

G. Borgstahl, J. Ohren, J. Habel, 2001, Acta crystallographica. Section D, Biological crystallography.

Interplay of DNA damage and cell cycle signaling at the level of human replication protein A.

Kaitlin A. Goettsch, G. Borgstahl, E. Kremmer, 2014, DNA repair.

Structural analysis of peroxide-soaked MnSOD crystals reveals side-on binding of peroxide to active-site manganese.

A. Vahedi-Faridi, J. Porta, G. Borgstahl, 2010, Journal of molecular biology.

RE SE EE DUB Proteasome Lysosome MVB / Late Endosome ESCRT Degradative Pathway EGF CblUbiquitin EGFR Associated Protiens Recycling Pathway

Nicholas Y. Palermo, G. Borgstahl, V. Band, 2012 .

Structure of the orthorhombic form of human inosine triphosphate pyrophosphatase.

J. Porta, G. Borgstahl, S. Kozmin, 2006, Acta crystallographica. Section F, Structural biology and crystallization communications.

MITOCHONDRIAL MANGANESE SUPEROXIDE DISMUTASE VARIANT WITH ILE 58 REPLACED BY THR

G. Borgstahl, J. Tainer, H. Parge, 1996 .

The 1.8 A structure of carbonmonoxy-beta 4 hemoglobin. Analysis of a homotetramer with the R quaternary structure of liganded alpha 2 beta 2 hemoglobin.

G. Borgstahl, P. Rogers, A. Arnone, 1994, Journal of molecular biology.

Beta 2-microglobulin regulates amyloid precursor-like protein 2 expression and the migration of pancreatic cancer cells

G. Borgstahl, J. Solheim, B. Poelaert, 2019, Cancer biology & therapy.

An Alternative Form of Replication Protein A Expressed in Normal Human Tissues Supports DNA Repair*

G. Borgstahl, S. Kowalczykowski, A. Sancar, 2009, The Journal of Biological Chemistry.

Physical and structural studies on the cryocooling of insulin crystals.

Edward H Snell, A. Vahedi-Faridi, G. Borgstahl, 2003, Acta crystallographica. Section D, Biological crystallography.

BEAM-ish: A Graphical User Interface for the Physical Characterization of Macromolecular Crystals

G. Borgstahl, H. Bellamy, E. Snell, 2000 .

The high-mosaicity illusion: revealing the true physical characteristics of macromolecular crystals.

G. Borgstahl, H. Bellamy, E. Snell, 2000, Acta crystallographica. Section D, Biological crystallography.

The Role of Histone H4 Biotinylation in the Structure of Nucleosomes

G. Borgstahl, Y. Lyubchenko, J. Zempleni, 2011, PloS one.

CyDisCo production of functional recombinant SARS‐CoV‐2 spike receptor binding domain

M. J. Broadhurst, G. Borgstahl, S. Khurana, 2021, Protein science : a publication of the Protein Society.

A Ferritin Nanoparticle-Based Zika Virus Vaccine Candidate Induces Robust Humoral and Cellular Immune Responses and Protects Mice from Lethal Virus Challenge

Bikash R. Sahoo, G. Borgstahl, Aryamav Pattnaik, 2023, Vaccines.

How can a single second sphere amino acid substitution cause reduction midpoint potential changes of hundreds of millivolts?

Laurie E. Grove, A. Vahedi-Faridi, J. Porta, 2007, Journal of the American Chemical Society.

The paradox of conformational constraint in the design of Cbl(TKB)-binding peptides

Eric A. Kumar, G. Borgstahl, A. Natarajan, 2013, Scientific Reports.

How to use dynamic light scattering to improve the likelihood of growing macromolecular crystals.

G. Borgstahl, 2007, Methods in molecular biology.

Purification and reconstitution of the connexin43 carboxyl terminus attached to the 4th transmembrane domain in detergent micelles.

G. Borgstahl, Fabien Kieken, P. Sorgen, 2008, Protein expression and purification.

Quantitative Analysis of Time-Resolved Laue Diffraction Patterns

G. Borgstahl, Z. Ren, K. Moffat, 1996 .

Investigating the Effect of Impurities on Macromolecule Crystal Growth in Microgravity

G. Borgstahl, H. Bellamy, E. Snell, 2001 .

Structural data on the aging of diethylphosphoryl-butyrylcholinesterase.

G. Borgstahl, P. Masson, O. Lockridge, 2005, Chemico-biological interactions.

Insect cell expression and purification of recombinant SARS‐COV‐2 spike proteins that demonstrate ACE2 binding

G. Borgstahl, S. Khurana, K. Bayles, 2022, Protein science : a publication of the Protein Society.

A test of macromolecular crystallization in microgravity: large well ordered insulin crystals.

E H Snell, A. Vahedi-Faridi, G. Borgstahl, 2001, Acta crystallographica. Section D, Biological crystallography.

EWALD: A macromolecular diffractometer for the second target station.

Jiao Y. Y. Lin, P. Zwart, G. Borgstahl, 2022, Review of Scientific Instruments.

The 1.9 A structure of deoxy beta 4 hemoglobin. Analysis of the partitioning of quaternary-associated and ligand-induced changes in tertiary structure.

G. Borgstahl, P. Rogers, A. Arnone, 1994, Journal of molecular biology.

The 1·8 Å Structure of Carbonmonoxy-β4 Hemoglobin

G. Borgstahl, P. Rogers, A. Arnone, 1994 .

CD28 Mutations in Peripheral T-Cell Lymphomagenesis and Progression

L. Staudt, A. Rosenwald, W. Chan, 2014 .

Structural basis for profilin-mediated actin nucleotide exchange.

J. Porta, G. Borgstahl, 2012, Journal of molecular biology.

Perfect Crystals: microgravity capillary counterdiffusion crystallization of human manganese superoxide dismutase for neutron crystallography

G. Borgstahl, K. Weiss, L. Coates, 2023, NPJ microgravity.

Crystal structure of Y34F mutant human mitochondrial manganese superoxide dismutase and the functional role of tyrosine 34.

G. Borgstahl, J. Tainer, M. Hickey, 1998, Biochemistry.

Structural Basis for Profilin-Mediated Actin

J. Porta, G. Borgstahl, 2012 .

A simple fluorescent assay for the discovery of protein-protein interaction inhibitors.

G. Borgstahl, D. Kelly, A. Natarajan, 2019, Analytical biochemistry.

Design, synthesis, and evaluation of a mitoxantrone probe (MXP) for biological studies

G. Borgstahl, A. Natarajan, Sarbjit Singh, 2023, bioRxiv.

Supplemental Information for : Human Replication Protein A , Rad 52 , ssDNA Complex : Stoichiometry and Evidence for Strand Transfer Regulation by Phosphorylation †

G. Borgstahl, G. Oakley, K. Dhar, 2009 .

Characterizing pathological imperfections in macromolecular crystals: lattice disorders and modulations

G. Borgstahl, J. Lovelace, 2020, Crystallography reviews.

Functional study of the P32T ITPA variant associated with drug sensitivity in humans.

G. Borgstahl, L. Marky, C. Frahm, 2009, Journal of molecular biology.

Erratum: The structure of human mitochondrial manganese superoxide dismutase reveals a novel tetrameric interface of two 4-helix bundles (Cell (1992) 71 (107-118))

G. Borgstahl, 1993 .

Interplay of DNA damage and cell cycle signaling at the level of human replication protein A.

Kaitlin A. Goettsch, G. Borgstahl, E. Kremmer, 2014, DNA repair.

Bacterial expression and purification of functional recombinant SARS-CoV-2 spike receptor binding domain

M. J. Broadhurst, G. Borgstahl, S. Khurana, 2021, bioRxiv.

First Results of Digital Topography Applied to Macromolecular Crystals

Robert M. Sweet, Edward H. Snell, Jeffrey J. Lovelace, 2004 .

Ripple: a program to collect and analyze digital topographic sequences

Jeffrey J. Lovelace, Gloria E. O. Borgstahl, G. Borgstahl, 2006 .

Advances in digital topography for characterizing imperfections in protein crystals

R. Pahl, Jeffrey J. Lovelace, Keith Brister, 2005 .

The Intriguing Mystery of RPA Phosphorylation in DNA Double-Strand Break Repair

G. Borgstahl, Valerie J. Fousek-Schuller, 2024, Genes.