C. Betzel

发表

Crystallization and structure analysis of Thermus flavus 5S rRNA helix B.

M. Vallazza, S. Banumathi, M. Perbandt, 2002, Acta crystallographica. Section D, Biological crystallography.

Native and Inhibited Structure of a Mu class-related Glutathione S-transferase from Plasmodium falciparum*

M. Perbandt, C. Betzel, E. Liebau, 2004, Journal of Biological Chemistry.

High-resolution crystal structure and biochemical characterization of a GH11 endoxylanase from Nectria haematococca

M. Perbandt, C. Betzel, H. Andaleeb, 2020, Scientific Reports.

Three-dimensional structure of system I of photosynthesis at 6 Å resolution

C. Betzel, P. Fromme, Z. Dauter, 1993, Nature.

Structural insights into serine protease inhibition by a marine invertebrate BPTI Kunitz-type inhibitor.

T. Pons, M. Perbandt, C. Betzel, 2012, Journal of structural biology.

Efficient UV detection of protein crystals enabled by fluorescence excitation at wavelengths longer than 300 nm.

Christian Betzel, Howard Einspahr, Karsten Dierks, 2010, Acta crystallographica. Section F, Structural biology and crystallization communications.

Pseudechis australis venomics: adaptation for a defense against microbial pathogens and recruitment of body transferrin.

C. Betzel, M. von Bergen, J. Seifert, 2011, Journal of proteome research.

Snake venomic of Crotalus durissus terrificus--correlation with pharmacological activities.

C. Betzel, M. von Bergen, J. Seifert, 2010, Journal of proteome research.

Interactions of the neurotoxin vipoxin in solution studied by dynamic light scattering.

C. Betzel, K. Dierks, D. Georgieva, 2004, Biophysical journal.

Crystallization and preliminary X-ray diffraction studies of a toxic phospholipase A2 from the venom of Vipera ammodytes meridionalis complexed to a synthetic inhibitor.

M. Perbandt, C. Betzel, Mahendra K. Jain, 2003, Biochimica et biophysica acta.

Design of specific peptide inhibitors of phospholipase A2: structure of a complex formed between Russell's viper phospholipase A2 and a designed peptide Leu-Ala-Ile-Tyr-Ser (LAIYS).

C. Betzel, T. Singh, P. Kaur, 2002, Acta crystallographica. Section D, Biological crystallography.

Modulation of phospholipase A2 activity generated by molecular evolution

C. Betzel, T. Singh, K. Rajashankar, 1999, Cellular and Molecular Life Sciences CMLS.

Crystallization and preliminary X-ray diffraction studies of the neurotoxic, heterodimeric phospholipase A2 from the Taiwan viper (Vipera russelli formosensis).

I. Tsai, C. Betzel, K. Rajashankar, 1999, Acta crystallographica. Section D, Biological crystallography.

Crystal structure of vipoxin at 2.0 Å: an example of regulation of a toxic function generated by molecular evolution

M. Perbandt, C. Betzel, T. Singh, 1997, FEBS letters.

The refined crystal structure of alpha-cobratoxin from Naja naja siamensis at 2.4-A resolution.

C. Betzel, A. Maelicke, K. Wilson, 1993, The Journal of biological chemistry.

Three‐dimensional structure of neurotoxin‐1 from Naja naja oxiana venom at 1.9 Å resolution

C. Betzel, K. Wilson, A. Nickitenko, 1993, FEBS letters.

Molecular structure of the acyl-enzyme intermediate in β-lactam hydrolysis at 1.7 Å resolution

C. Betzel, M. James, K. Sutoh, 1992, Nature.

Cm3+/Eu3+ induced structural, mechanistic and functional implications for calmodulin.

C. Betzel, T. Abe, Y. Komeiji, 2019, Physical chemistry chemical physics : PCCP.

Snake Venom Peptides: Tools of Biodiscovery

C. Betzel, Aisha Munawar, S. A. Ali, 2018, Toxins.

Dynamic Light Scattering (DLS)

C. Betzel, S. Falke, 2019, Radiation in Bioanalysis.

Dynamic Light Scattering in Protein Crystallization Droplets: Adaptations for Analysis and Optimization of Crystallization Processes

C. Betzel, A. Meyer, K. Dierks, 2008 .

Structure of the polypeptide crotamine from the Brazilian rattlesnake Crotalus durissus terrificus.

C. Betzel, B. Sankaran, M. Coronado, 2013, Acta crystallographica. Section D, Biological crystallography.

Cavity mutants of Savinase. Crystal structures and differential scanning calorimetry experiments give hints of the function of the buried water molecules in subtilisins.

C. Betzel, O. Olsen, J. Pedersen, 1994, Journal of molecular biology.

Electronic damage in S atoms in a native protein crystal induced by an intense X-ray free-electron laser pulse

H. N. Chapman, C. H. Yoon, H. Fleckenstein, 2015, Structural dynamics.

Two variants of the major serine protease inhibitor from the sea anemone Stichodactyla helianthus, expressed in Pichia pastoris.

C. Betzel, U. Hahn, R. García-Fernández, 2016, Protein expression and purification.

A multicrystal diffraction data-collection approach for studying structural dynamics with millisecond temporal resolution

M. Perbandt, C. Betzel, G. Bourenkov, 2016, IUCrJ.

EXPRESSION, PURIFICATION AND PRELIMINARY X-RAY DIFFRACTION OF A PATHOGENIC BACTERIAL PROTEASE FROM STENOTROPHOMONAS MALTOPHILIA

C. Betzel, W. Weber, S. Windhorst, 2014 .

The complex between mesentericopeptidase and eglin-C.

C. Betzel, Z. Dauter, K. Wilson, 1996, Advances in experimental medicine and biology.

Protein-crystal detection with a compact multimodal multiphoton microscope

C. Betzel, F. Kärtner, S. Falke, 2020, Communications biology.

Multi-channel in situ dynamic light scattering instrumentation enhancing biological small-angle X-ray scattering experiments at the PETRA III beamline P12.

C. Betzel, D. Svergun, S. Falke, 2018, Journal of synchrotron radiation.

Inhibition of SARS-CoV-2 main protease by allosteric drug-binding

Diana C. F. Monteiro, H. Chapman, C. Betzel, 2020, bioRxiv.

Massive X-ray screening reveals two allosteric drug binding sites of SARS-CoV-2 main protease

Diana C. F. Monteiro, H. Chapman, C. Betzel, 2020 .

Proteomic Investigations of Two Pakistani Naja Snake Venoms Species Unravel the Venom Complexity, Posttranslational Modifications, and Presence of Extracellular Vesicles

C. Betzel, H. Schlüter, A. Ullah, 2020, Toxins.

The Sequence and a Three-Dimensional Structural Analysis Reveal Substrate Specificity among Snake Venom Phosphodiesterases

C. Betzel, K. Ullah, Shafiq ur Rehman, 2019, Toxins.

Crystallographic portrayal of different conformational states of a Lys49 phospholipase A₂ homologue: insights into structural determinants for myotoxicity and dimeric configuration.

C. Betzel, R. Arni, M. Murakami, 2012, International journal of biological macromolecules.

Crystallization and preliminary diffraction studies of the structural domain E of Thermus flavus 2S rRNA

C. Betzel, V. Erdmann, K. Wilson, 1995 .

Crystallization and Diffraction Studies of Thermus Flavus 5S rRNA and Synthetic Fragments of the 5S rRNA

C. Betzel, V. Erdmann, K. Wilson, 1993 .

Crystallization and preliminary diffraction studies of 5 S rRNA from the thermophilic bacterium Thermus flavus.

C. Betzel, V. Erdmann, Z. Dauter, 1991, Journal of molecular biology.

Protein microheterogeneity and crystal habits: the case of epidermal growth factor receptor isoforms as isolated in a multicompartment electrolyzer with isoelectric membranes.

C. Betzel, P. Righetti, N. Günther, 1994, Journal of chromatography. A.

CHL1 Is a Selective Organizer of the Presynaptic Machinery Chaperoning the SNARE Complex

C. Betzel, M. Schachner, L. Redecke, 2010, PloS one.

Pulsed electric fields induce modulation of protein liquid-liquid phase separation.

C. Betzel, S. Falke, H. Brognaro, 2020, Soft matter.

Isolation and characterization of Bradykinin potentiating peptides from Agkistrodon bilineatus venom

C. Betzel, P. Spencer, Aisha Munawar, 2016, Proteome Science.

Design of Specific Peptide Structures and Subtilisin Enzyme Inhibitors Using α, β-Dehydro-Residues

C. Betzel, T. Singh, P. Sharma, 1996 .

Fluorescence decay of tryptophans in serine proteinases from microorganisms: relation to X-ray models.

C. Betzel, K. Wilson, N. Genov, 1996, Advances in experimental medicine and biology.

X‐Ray structure of the antibiotic bacitracin A

C. Betzel, K. Wilson, W. Höhne, 1991, FEBS letters.

Three dimensional structure of the antibiotic bacitracin A complexed to two different subtilisin proteases: novel mode of enzyme inhibition.

C. Betzel, Z. Dauter, M. Hennig, 1996, Advances in experimental medicine and biology.

X-ray structures of uridine phosphorylase from Vibrio cholerae in complexes with uridine, thymidine, uracil, thymine, and phosphate anion: Substrate specificity of bacterial uridine phosphorylases

C. Betzel, A. Mironov, V. Balaev, 2016 .

Preliminary Crystallographic Analysis of a Cruciferin Protein from Seeds of Moringa oleifera

M. Perbandt, C. Betzel, N. Yousef, 2014, The Protein Journal.

Structural insights into selectivity and cofactor binding in snake venom L-amino acid oxidases.

C. Betzel, R. Arni, M. Murakami, 2012, Biochemical and biophysical research communications.

The mistletoe lectin I--phloretamide structure reveals a new function of plant lectins.

J. Barciszewski, C. Betzel, V. Erdmann, 2007, Biochemical and biophysical research communications.

Thrombin-like enzymes from snake venom: Structural characterization and mechanism of action.

C. Betzel, K. Ullah, A. Ullah, 2018, International journal of biological macromolecules.

The conserved hypothetical protein Tb427.10.13790 is required for cytokinesis in Trypanosoma brucei.

C. Betzel, M. Duszenko, C. Mudogo, 2018, Acta tropica.

Venomics of the Australian eastern brown snake (Pseudonaja textilis): Detection of new venom proteins and splicing variants.

C. Betzel, H. Schlüter, P. Spencer, 2015, Toxicon : official journal of the International Society on Toxinology.

The venomics of Bothrops alternatus is a pool of acidic proteins with predominant hemorrhagic and coagulopathic activities.

C. Betzel, M. von Bergen, J. Seifert, 2010, Journal of proteome research.

Identification of Peptides in Mass Spectrometric Proteomics Data with the PRIDE Cluster Spectral Library and a Neural-net-based Machine-learned Scoring Function

C. Betzel, H. Schlüter, M. Wurlitzer, 2019 .

Structure-based identification of inositol polyphosphate 1-phosphatase from Entamoeba histolytica.

C. Betzel, S. Gourinath, Khaja Faisal Tarique, 2014, Acta crystallographica. Section D, Biological crystallography.

C-13 NMR, X-ray and differential scanning calorimetry investigations of truncated BPTI mutants: salt bridge formation

C. Betzel, O. Olsen, P. Hansen, 1998 .

Real-Time Observation of Protein Dense Liquid Cluster Evolution during Nucleation in Protein Crystallization

M. Perbandt, C. Betzel, A. Meyer, 2017 .

Crystal structure of beta-D-cellotetraose hemihydrate with implications for the structure of cellulose II.

C. Betzel, W. Saenger, N. Krauß, 1994, Science.

pH dependence of the catalytic activity of a subtilisin-like proteinase.

C. Betzel, K. Wilson, G. Lange, 1996, Advances in experimental medicine and biology.

Autoproteolytic stability of a trypsin from the marine crab Cancer pagurus.

C. Betzel, M. von Bergen, L. Redecke, 2008, Biochemical and biophysical research communications.

Structural characterization of 12S seed Cruciferin from Eruca sativa in solution applying small-angle X-ray scattering

C. Betzel, A. Wahid, S. Falke, 2019, Pakistan Journal of Botany.

Structure and activity of the DHNA Coenzyme-A Thioesterase from Staphylococcus aureus providing insights for innovative drug development

M. Perbandt, C. Betzel, C. Wrenger, 2021, Scientific Reports.

Novel approaches for the lipid sponge phase crystallization of the Rhodobacter sphaeroides photosynthetic reaction center

C. Betzel, A. Gabdulkhakov, L. Vasilieva, 2020, IUCrJ.

Microfluidic Chips for In Situ Crystal X-ray Diffraction and In Situ Dynamic Light Scattering for Serial Crystallography

H. Chapman, M. Perbandt, C. Betzel, 2018, Journal of visualized experiments : JoVE.

De novo protein structure determination by heavy-atom soaking in lipidic cubic phase and SIRAS phasing using serial synchrotron crystallography

H. Chapman, M. Perbandt, C. Betzel, 2018, IUCrJ.

Biophysical and enzymatic properties of aminoglycoside adenylyltransferase AadA6 from Pseudomonas aeruginosa

C. Betzel, I. Sarrou, D. Oberthür, 2015, Biochemistry and biophysics reports.

Purification, crystallization, and X-ray diffraction studies of lactotransferrin from buffalo colostrum.

C. Betzel, T. Singh, A. Srinivasan, 1992, Archives of biochemistry and biophysics.

Spectroscopic investigation of calcium binding sites in the neurotoxin vipoxin and its components-relation with the X-ray structure.

C. Betzel, D. Georgieva, N. Genov, 2000, Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.

Crystallization of the bifunctional proteinase/amylase inhibitor PKI‐3 and of its complex with proteinase K

C. Betzel, W. Saenger, K. Jany, 1986, FEBS letters.

Isolation, purification, crystallization and preliminary crystallographic studies of a chitinase from Crocus vernus.

M. Perbandt, C. Betzel, A. Meyer, 2011, Acta crystallographica. Section F, Structural biology and crystallization communications.

Crystallization and preliminary X-ray diffraction analysis of an Escherichia coli tRNA(Gly) acceptor-stem microhelix.

M. Perbandt, C. Betzel, V. Erdmann, 2007, Acta crystallographica. Section F, Structural biology and crystallization communications.

Human tRNA(Gly) acceptor-stem microhelix: crystallization and preliminary X-ray diffraction analysis at 1.2 A resolution.

M. Perbandt, C. Betzel, V. Erdmann, 2007, Acta crystallographica. Section F, Structural biology and crystallization communications.

Magnesium-dependent Serratia marcescens endonuclease: three-dimensional structure at 1.1 Å resolution and molecular mechanism of enzyme action

M. Perbandt, C. Betzel, V. Lunin, 2000 .

Synchrotron X-ray and Neutron Radiation in Protein Crystallography - Present and Future

C. Betzel, W. Saenger, 1988 .

Structural basis to repurpose boron-based proteasome inhibitors Bortezomib and Ixazomib as β-lactamase inhibitors

H. Rohde, M. Aepfelbacher, M. Perbandt, 2022, Scientific Reports.

Real-time investigation of dynamic protein crystallization in living cells

C. Betzel, M. Duszenko, R. Schönherr, 2015, Structural dynamics.

UV-light-induced conversion and aggregation of prion proteins.

C. Betzel, P. May, L. Redecke, 2009, Free radical biology & medicine.

Venom on ice: first insights into Antarctic octopus venoms.

C. Betzel, J. Norman, E. Undheim, 2010, Toxicon : official journal of the International Society on Toxinology.

Interactions of recombinant prions with compounds of therapeutical significance.

C. Betzel, M. von Bergen, L. Redecke, 2006, Biochemical and biophysical research communications.

Crystallization and preliminary X-ray diffraction analysis of an L-amino-acid oxidase from Bothrops jararacussu venom.

C. Betzel, M. Coronado, R. Arni, 2012, Acta crystallographica. Section F, Structural biology and crystallization communications.

Purification, crystallization and preliminary X-ray diffraction analysis of ThiM from Staphylococcus aureus.

M. Perbandt, C. Betzel, C. Wrenger, 2011, Acta crystallographica. Section F, Structural biology and crystallization communications.

Purification, crystallization and preliminary X-ray diffraction analysis of the thiaminase type II from Staphylococcus aureus.

M. Perbandt, C. Betzel, C. Wrenger, 2011, Acta crystallographica. Section F, Structural biology and crystallization communications.

Crystallization and X-ray diffraction analysis of an ‘all-locked’ nucleic acid duplex derived from a tRNASer microhelix

C. Betzel, V. Erdmann, J. Fürste, 2009 .

On Isolated Complexes of Reaction Center I and X-Ray Characterization of Single Crystals

C. Betzel, Z. Dauter, W. Saenger, 1990 .

Crystallization and preliminary X-ray diffraction studies of trypsin-like proteases from the gastric fluid of the marine crab Cancer pagurus.

M. Perbandt, C. Betzel, L. Redecke, 2007, Acta Crystallographica. Section F : Structural Biology and Crystallization Communications.

Dimerization of the Major Birch Pollen Allergen Bet v 1 Is Important for its In Vivo IgE-Cross-Linking Potential in Mice1

C. Betzel, A. Bergmann, W. Keller, 2005, The Journal of Immunology.

IgE-Cross-Linking Potential in Mice Allergen Bet v 1 Is Important for its In Vivo Dimerization of the Major Birch Pollen

C. Betzel, A. Bergmann, W. Keller, 2005 .

Screening of Protease Inhibitory Activity in Aqueous Extracts of Marine Invertebrates from Cuban Coast

C. Betzel, R. García-Fernández, L. González, 2016 .

Utilisation of adsorption and desorption for simultaneously improving protein crystallisation success rate and crystal quality

C. Betzel, J. Liu, D. Oberthuer, 2014, Scientific Reports.

Crystallization and Preliminary Diffraction Data of a Major Pollen Allergen

M. Perbandt, C. Betzel, Z. Dauter, 1996, The Journal of Biological Chemistry.

The Komagataeibacter europaeus GqqA is the prototype of a novel bifunctional N-Acyl-homoserine lactone acylase with prephenate dehydratase activity

M. Perbandt, C. Betzel, W. Hinrichs, 2021, Scientific Reports.

3-D Model of the bee venom acid phosphatase: insights into allergenicity.

C. Betzel, D. Georgieva, N. Genov, 2009, Biochemical and biophysical research communications.

Intrinsically disordered plant protein PARCL colocalizes with RNA in phase-separated condensates whose formation can be regulated by mutating the PLD

Richard J. Morris, C. Betzel, D. Svergun, 2022, The Journal of biological chemistry.

Multi-Step Concanavalin A Phase Separation and Early-Stage Nucleation Monitored Via Dynamic and Depolarized Light Scattering

C. Betzel, S. Falke, H. Brognaro, 2019, Crystals.

Isolation and initial structural characterization of a 27 kDa protein from Zingiber officinale

C. Betzel, H. Schlüter, S. Falke, 2018 .

Highly affine and selective aptamers against cholera toxin as capture elements in magnetic bead-based sandwich ELAA.

C. Betzel, S. Falke, M. Fischer, 2018, Journal of biotechnology.

SAXS and other spectroscopic analysis of 12S cruciferin isolated from the seeds of Brassica nigra

C. Betzel, S. Falke, S. Mahmood, 2017 .

Structural characterization and antibacterial activity of silver nanoparticles synthesized using a low-molecular-weight Royal Jelly extract

C. Betzel, S. Falke, K. Lorenzen, 2022, Scientific Reports.

Strategy to design peptide inhibitors: Structure of a complex of proteinase K with a designed octapeptide inhibitor N‐Ac‐Pro‐Ala‐Pro‐Phe‐DAla‐Ala‐Ala‐Ala‐NH2 at 2.5 Å resolution

C. Betzel, T. Singh, A. Saxena, 1996, Protein science : a publication of the Protein Society.

Staphylococcus aureus thiaminase II: oligomerization warrants proteolytic protection against serine proteases.

M. Perbandt, C. Betzel, D. Svergun, 2013, Acta crystallographica. Section D, Biological crystallography.

Structure of the recombinant BPTI/Kunitz-type inhibitor rShPI-1A from the marine invertebrate Stichodactyla helianthus.

T. Pons, M. Perbandt, C. Betzel, 2012, Acta crystallographica. Section F, Structural biology and crystallization communications.

Expression, purification, crystallization and preliminary X-ray structure analysis of Vibrio cholerae uridine phosphorylase in complex with thymidine.

C. Betzel, A. Mironov, A. Shtil, 2012, Acta crystallographica. Section F, Structural biology and crystallization communications.

Crystallization and preliminary X-ray diffraction analysis of a tRNASer acceptor-stem microhelix.

Klaus D. M. Hennig, M. Perbandt, C. Betzel, 2006, Acta crystallographica. Section F, Structural biology and crystallization communications.

Antiviral activity of natural phenolic compounds in complex at an allosteric site of SARS-CoV-2 papain-like protease

H. Chapman, M. Perbandt, C. Betzel, 2022, Communications Biology.

Reply to Comments on Proteomic Investigations of Two Pakistani Naja Snake Venom Species Unravel the Venom Complexity, Posttranslational Modifications, and Presence of Extracellular Vesicles. Toxins 2020, 12, 669

C. Betzel, H. Schlüter, Aisha Munawar, 2020, Toxins.

Preliminary X-ray diffraction studies of the external functional unit RtH2-e from the Rapana thomasiana.

M. Perbandt, C. Betzel, W. Rypniewski, 2001, Acta crystallographica. Section D, Biological crystallography.

Crystallization, preliminary X-ray analysis and amino acid sequence studies of an “external” functional unit from the Rapana thomasiana grosse (mollusc, gastropod) hemocyanin

M. Perbandt, C. Betzel, W. Rypniewski, 2001 .

Isolation, purification, crystallization and preliminary X-ray analysis of beta 1-bungarotoxin from Bungarus caeruleus (Indian common krait).

C. Betzel, T. Singh, S. Sharma, 1999, Acta crystallographica. Section D, Biological crystallography.

Crystallization and preliminary X‐ray analysis of leukemia inhibitory factor

C. Betzel, Z. Dauter, T. Boone, 1993, FEBS letters.

Crystallization and preliminary X-ray analysis of vipoxin, a complex between a toxic phospholipase A2 and its natural polypeptide inhibitor.

C. Betzel, K. Wilson, N. Genov, 1993, Journal of molecular biology.

Structure-Function Relationship in Heterodimeric Neurotoxin PLA2s from Viperidae Snakes Inhabiting Europe, South America, and Asia

C. Betzel, R. Arni, D. Georgieva, 2016 .

Preliminary investigation of the three-dimensional structure of Salmonella typhimurium uridine phosphorylase in the crystalline state.

C. Betzel, A. Mironov, M. Garber, 2005, Acta crystallographica. Section F, Structural biology and crystallization communications.

Growing Protein Crystals with Distinct Dimensions Using Automated Crystallization Coupled with In Situ Dynamic Light Scattering

M. Perbandt, C. Betzel, A. Meyer, 2018, Journal of visualized experiments : JoVE.

Single-drop optimization of protein crystallization.

C. Betzel, R. Hilgenfeld, R. Schöpflin, 2012, Acta crystallographica. Section F, Structural biology and crystallization communications.

The structure of a functional unit from the wall of a gastropod hemocyanin offers a possible mechanism for cooperativity.

M. Perbandt, C. Betzel, E. Guthöhrlein, 2003, Biochemistry.

Three-dimensional structure of the Fab fragment of a neutralizing antibody to human rhinovirus serotype

C. Betzel, H. Auer, D. Blaas, 2002 .

Flip-flop hydrogen bonding in a partially disordered system

C. Betzel, B. Hingerty, W. Saenger, 1982, Nature.

Topology of the polypeptide chain in the complex of agglutinin from castor bean seeds with β-D-galactose in the crystalline state

C. Betzel, B. Vainshtein, S. Nikonov, 2001 .

Crystal structure of the disintegrin heterodimer from saw-scaled viper (Echis carinatus) at 1.9 A resolution.

M. Perbandt, C. Betzel, Sujata Sharma, 2005, Biochemistry.

Comparative analysis of the venom proteomes of Vipera ammodytes ammodytes and Vipera ammodytes meridionalis.

C. Betzel, M. von Bergen, D. Georgieva, 2008, Journal of proteome research.

Synthetic human prion protein octapeptide repeat binds to the proteinase K active site.

M. Perbandt, C. Betzel, L. Redecke, 2004, Biochemical and biophysical research communications.

X-ray structure analysis of food allergens.

C. Betzel, 2001, Journal of chromatography. B, Biomedical sciences and applications.

Structure and function of proteins involved in milk allergies.

C. Betzel, T. Singh, S. Sharma, 2001, Journal of chromatography. B, Biomedical sciences and applications.

An investigation of the savinase water channel: implications of cavity mutations.

C. Betzel, O. Olsen, J. Pedersen, 1996, Advances in experimental medicine and biology.

Spectroscopic studies on proteinase K and subtilisin DY. Relation to X-ray models.

C. Betzel, K. Wilson, N. Genov, 2009, International journal of peptide and protein research.

Genome and Secretome Analysis of Staphylotrichum longicolleum DSM105789 Cultured on Agro-Residual and Chitinous Biomass

C. Betzel, H. Schlüter, C. Wrenger, 2021, Microorganisms.

Insights into the genome and secretome of Fusarium metavorans DSM105788 by cultivation on agro-residual biomass and synthetic nutrient sources

C. Betzel, H. Schlüter, Stefan Janssen, 2021, Biotechnology for Biofuels.

Crystal structure of a calcium‐induced dimer of two isoforms of cobra phospholipase A2 at 1.6 Å resolution

M. Perbandt, C. Betzel, T. Singh, 2005, Proteins.

Synthesis of stoichiometric nano crystalline hydroxyapatite by ethanol-based sol–gel technique at low temperature

C. Betzel, K. Dierks, S. Kalkura, 2004 .

Amino acid sequence and glycosylation of functional unit RtH2-e from Rapana thomasiana (gastropod) hemocyanin.

C. Betzel, N. Genov, W. Voelter, 2002, Archives of biochemistry and biophysics.

Structure of the complex of proteinase K with a substrate analogue hexapeptide inhibitor at 2.2-A resolution.

C. Betzel, K. Wilson, W. Saenger, 1994, The Journal of biological chemistry.

Three-dimensional structure of proteinase K at 0.15-nm resolution.

C. Betzel, W. Saenger, G. Pal, 1988, European journal of biochemistry.

X‐ray and model‐building studies on the specificity of the active site of proteinase K

C. Betzel, J. Bajorath, K. Wilson, 1988, Proteins.

Active‐site geometry of proteinase K

C. Betzel, W. Saenger, M. Struck, 1986, FEBS letters.

Topography of cyclodextrin inclusion complexes, part 20. Circular and flip-flop hydrogen bonding in .beta.-cyclodextrin undecahydrate: a neutron diffraction study

Christian Betzel, Wolfram Saenger, C. Betzel, 1984 .

(β-Cyclodextrin)2·KI7·9 H2O. Spatial fitting of a polyiodide chain to a given matrix

C. Betzel, B. Hingerty, J. Hamilton, 1983 .

An Amylose Antiparallel Double Helix at Atomic Resolution

C. Betzel, W. Saenger, W. Hinrichs, 1987, Science.

Neutron diffraction of alpha, beta and gamma cyclodextrins: hydrogen bonding patterns.

C. Betzel, B. Hingerty, W. Saenger, 1984, Journal of biomolecular structure & dynamics.

Crystal structure of the alkaline proteinase Savinase from Bacillus lentus at 1.4 A resolution.

K S Wilson, C. Betzel, S. Hastrup, 1992, Journal of molecular biology.

Molecular dynamics refinement of a thermitase-eglin-c complex at 1.98 A resolution and comparison of two crystal forms that differ in calcium content.

C. Betzel, W. Hol, Z. Dauter, 1989, Journal of molecular biology.

Effect of macromolecular mass transport in microgravity protein crystallization

M. Perbandt, L. DeLucas, C. Betzel, 2019, Gravitational and Space Research.

Crystallization of proteinase K complexed with substrate analogue peptides on US space missions STS-91 and STS-95

K. Moore, L. DeLucas, C. Betzel, 2000 .

Eruca sativa seed napin structural insights and thorough functional characterization

C. Betzel, S. Falke, Q. Ali, 2021, Scientific Reports.

Primary Structure and Molecular Modeling of Mistletoe Lectin I fromViscum album

C. Betzel, S. Eschenburg, W. Voelter, 1998 .

Primary structure and molecular modeling of mistletoe lectin I from Viscum album.

C. Betzel, S. Eschenburg, W. Voelter, 1998, Biochemical and Biophysical Research Communications - BBRC.

Complete structure determination of N‐acetyl‐D‐galactosamine‐binding mistletoe lectin‐3 from Viscum album L. album

C. Betzel, W. Voelter, R. Wacker, 2005, Journal of peptide science : an official publication of the European Peptide Society.

Mistletoe lectin I in complex with galactose and lactose reveals distinct sugar-binding properties.

C. Betzel, T. Singh, R. Arni, 2005, Acta crystallographica. Section F, Structural biology and crystallization communications.

Crystal structure of mistletoe lectin I from Viscum album.

M. Perbandt, C. Betzel, T. Maier, 1999, Biochemical and biophysical research communications.

cDNA cloning and characterization of a ribosome inactivating protein of a hemi-parasitic plant (Viscum album L.) from North-Western Himalaya (India)

C. Betzel, T. Singh, R. Sharma, 2005 .

Primary structure, isoforms, and molecular modeling of a chitin-binding mistletoe lectin.

C. Betzel, E. Guthöhrlein, W. Voelter, 2001, Archives of biochemistry and biophysics.

Pseudechis guttatus venom proteome: Insights into evolution and toxin clustering.

C. Betzel, H. Schlüter, P. Spencer, 2014, Journal of proteomics.

Production, Purification and Characterization of Recombinant, Full-Length Human Claudin-1

C. Betzel, J. McKeating, N. Bonander, 2013, PloS one.

First experimental evidence for the preferential stabilization of the natural D- over the nonnatural L-configuration in nucleic acids.

M. Perbandt, C. Betzel, S. Klußmann, 2007, RNA.

Conformational states of the Rapana thomasiana hemocyanin and its substructures studied by dynamic light scattering and time-resolved fluorescence spectroscopy.

C. Betzel, K. Dierks, D. Georgieva, 2005, Biophysical journal.

Contribution of Disulfide Bonds and Calcium to Molluscan Hemocyanin Stability

M. Perbandt, C. Betzel, D. Georgieva, 2004, Zeitschrift für Naturforschung C - A Journal of Biosciences.

Structural analysis and molecular modelling of the Cu/Zn-SOD from fungal strain Humicola lutea 103.

C. Betzel, B. Atanasov, M. Angelova, 2011, Spectrochimica Acta Part A - Molecular and Biomolecular Spectroscopy.

Molecular crowding and RNA synergize to promote phase separation, microtubule interaction, and seeding of Tau condensates

C. Betzel, E. Mandelkow, T. Mielke, 2022, The EMBO journal.

Biomolecular Tau condensation is linked to Tau accumulation at the nuclear envelope

C. Betzel, E. Mandelkow, T. Mielke, 2022, bioRxiv.

Structure of catalase-A from Saccharomyces cerevisiae.

C. Betzel, P. Alzari, M. Maté, 1999, Journal of molecular biology.

Crystal structure of catalase HPII from Escherichia coli.

C. Betzel, J. Bravo, J. Tormo, 1995, Structure.

Spectroscopic investigation of phenolic groups ionization in the vipoxin neurotoxic phospholipase A2: comparison with the X-ray structure in the region of the tyrosyl residues.

C. Betzel, K. Rajashankar, D. Georgieva, 1998, Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.

Bacillus licheniformis Variant DY Proteinase: Specificity in Relation to the Geometry of the Substrate Recognition Site

C. Betzel, D. Georgieva, N. Genov, 2005, Current Microbiology.

Fluorescence properties of Savinase®: the X-ray structure in the region of the tryptophyl residues

C. Betzel, D. Georgieva, P. Nikolov, 1999 .

Steady-state and time-resolved fluorescence of Esperase: comparison with the X-ray structure in the region of the two tryptophans.

C. Betzel, D. Georgieva, P. Nikolov, 1998, Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.

Fluorescence properties of native and photooxidised proteinase K: the X-ray model in the region of the two tryptophans.

C. Betzel, K. Wilson, N. Genov, 1992, Biochimica et biophysica acta.

Catalytic Efficiencies of Alkaline Proteinases from Microorganisms

C. Betzel, D. Georgieva, N. Genov, 2006, Zeitschrift fur Naturforschung. C, Journal of biosciences.

Oligomerization of the proteolytic products is an intrinsic property of prion proteins.

M. Perbandt, C. Betzel, L. Redecke, 2004, Biochemical and biophysical research communications.

Spectroscopic properties and stability of the neurotoxic complex. Vipoxin and its components.

C. Betzel, K. Rajashankar, N. Genov, 1998, Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.

Stability of subtilisins and related proteinases (subtilases).

C. Betzel, K. Wilson, N. Genov, 2009, International journal of peptide and protein research.

Reactivity and Function of Carboxyl Groups in Bacterial and Fungal Proteinases (Subtilases): Relation to X—Ray Models

C. Betzel, N. Genov, K. Idakieva, 1995 .

Fluorescence properties of subtilisins and related proteinases (subtilases): relation to X-ray models.

C. Betzel, K. Wilson, N. Genov, 1993, Journal of photochemistry and photobiology. B, Biology.

Actinomycins as proteinase inhibitors.

C. Betzel, N. Genov, P. Dolashka, 1993, Biochimica et biophysica acta.

Differences in the specificities of the highly alkalophilic proteinases Savinase and Esperase imposed by changes in the rigidity and geometry of the substrate binding sites.

C. Betzel, D. Georgieva, N. Genov, 2001, Archives of biochemistry and biophysics.

Complex between the subtilisin from a mesophilic bacterium and the leech inhibitor eglin-C.

K S Wilson, Z Dauter, C. Betzel, 1991, Acta crystallographica. Section B, Structural science.

Hydrazones and Thiosemicarbazones Targeting Protein-Protein-Interactions of SARS-CoV-2 Papain-like Protease

C. Betzel, W. Hinrichs, M. Garcia-Alai, 2022, Frontiers in Chemistry.

X-ray structural studies of the fungal laccase from Cerrena maxima

C. Betzel, G. Kachalova, V. Lamzin, 2006, JBIC Journal of Biological Inorganic Chemistry.

Frontiers in Natural Product Chemistry

C. Betzel, I. Fleming, M. Rajoka, 2009 .

In vivo protein crystallization in combination with highly brilliant radiation sources offers novel opportunities for the structural analysis of post-translationally modified eukaryotic proteins.

C. Betzel, D. Oberthuer, M. Duszenko, 2015, Acta crystallographica. Section F, Structural biology communications.

Crystal structure of the jacalin-T-antigen complex and a comparative study of lectin-T-antigen complexes.

S. Banumathi, C. Betzel, A. Surolia, 2002, Journal of molecular biology.

Immunosuppressive Yersinia Effector YopM Binds DEAD Box Helicase DDX3 to Control Ribosomal S6 Kinase in the Nucleus of Host Cells

M. Aepfelbacher, M. Perbandt, C. Betzel, 2016, PLoS pathogens.

Enzymatic toxins from snake venom: structural characterization and mechanism of catalysis

C. Betzel, Sujata Sharma, R. Kini, 2011, The FEBS journal.

Regulation of catalytic function by molecular association: structure of phospholipase A2 from Daboia russelli pulchella (DPLA2) at 1.9 A resolution.

C. Betzel, T. Singh, P. Kaur, 2001, Acta crystallographica. Section D, Biological crystallography.

Isolation, crystallization and preliminary X-ray diffraction analysis of L-amino-acid oxidase from Vipera ammodytes ammodytes venom.

M. Perbandt, C. Betzel, D. Georgieva, 2008, Acta crystallographica. Section F, Structural biology and crystallization communications.

Crystallization and Preliminary X-ray Analysis of a Low Density Lipoprotein from Human Plasma*

C. Betzel, M. Sára, R. Prassl, 1996, The Journal of Biological Chemistry.

The X-ray structure of Salmonella typhimurium uridine nucleoside phosphorylase complexed with 2,2'-anhydrouridine, phosphate and potassium ions at 1.86 A resolution.

C. Betzel, R. Efremov, A. Shtil, 2010, Acta crystallographica. Section D, Biological crystallography.

X-ray structure of Salmonella typhimurium uridine phosphorylase complexed with 5-fluorouracil and molecular modelling of the complex of 5-fluorouracil with uridine phosphorylase from Vibrio cholerae.

C. Betzel, A. Mironov, I. Agapov, 2012, Acta crystallographica. Section D, Biological crystallography.

Structural and Functional Analysis of Pyrimidine Nucleoside Phosphorylases of the NP-I and NP-II Families in Complexes with 6-Methyluracil

C. Betzel, A. Mironov, V. Balaev, 2018 .

Crystallization and preliminary X-ray study of Vibrio cholerae uridine phosphorylase in complex with 6-methyluracil.

C. Betzel, A. Mironov, A. Gabdulkhakov, 2014, Acta crystallographica. Section F, Structural biology communications.

Three-dimensional structures of unligated uridine phosphorylase from Yersinia pseudotuberculosis at 1.4 Å resolution and its complex with an antibacterial drug

C. Betzel, A. Mironov, V. Balaev, 2015 .

Protein Crystallization on the International Space Station ISS

Günter Ruyters, Christian Betzel, C. Betzel, 2017 .

Isolation, crystallization and preliminary crystallographic analysis of Salmonella typhimurium uridine phosphorylase crystallized with 2,2'-anhydrouridine.

C. Betzel, G. Kachalova, V. Timofeev, 2007, Acta crystallographica. Section F, Structural biology and crystallization communications.

Structural investigation of the thymidine phosphorylase from Salmonella typhimurium in the unliganded state and its complexes with thymidine and uridine.

C. Betzel, A. Mironov, V. Balaev, 2016, Acta crystallographica. Section F, Structural biology communications.

The first Jack bean urease (Canavalia ensiformis) complex obtained at 1.52 resolution

C. Betzel, M. Choudhary, A. Begum, 2012 .

Substrate specificity of pyrimidine nucleoside phosphorylases of NP-II family probed by X-ray crystallography and molecular modeling

C. Betzel, A. Mironov, V. Balaev, 2016 .

Purification, crystallization and preliminary X-ray crystallographic analysis of lactoperoxidase from buffalo milk.

C. Betzel, Z. Dauter, T. Singh, 1995, Acta crystallographica. Section D, Biological crystallography.

Protein phase separation and determinants of in cell crystallization

C. Betzel, S. Falke, H. Brognaro, 2019, Traffic.

Biperiden and mepazine effectively inhibit MALT1 activity and tumor growth in pancreatic cancer

C. Betzel, G. Sauter, J. Izbicki, 2020, International journal of cancer.

Serial crystallography on in vivo grown microcrystals using synchrotron radiation

Henry N. Chapman, Christian Betzel, Francesco Stellato, 2014, IUCrJ.

Tracing transport of protein aggregates in microgravity versus unit gravity crystallization

L. DeLucas, C. Betzel, S. Falke, 2022, npj Microgravity.

Exosomal cellular prion protein drives fibrillization of amyloid beta and counteracts amyloid beta‐mediated neurotoxicity

C. Betzel, M. Glatzel, C. Verderio, 2016, Journal of neurochemistry.

Proteome analysis of snake venom toxins: pharmacological insights

C. Betzel, R. Arni, D. Georgieva, 2008, Expert review of proteomics.

Structure of the bifunctional inhibitor of trypsin and alpha-amylase from ragi seeds at 2.2 A resolution.

C. Betzel, T. Singh, S. Gourinath, 2000, Acta crystallographica. Section D, Biological crystallography.

Crystal Structure of Himalayan Mistletoe Ribosome-inactivating Protein Reveals the Presence of a Natural Inhibitor and a New Functionally Active Sugar-binding Site*

C. Betzel, T. Singh, P. Kaur, 2005, Journal of Biological Chemistry.

Latest Insights and Methods in Analyzing Liquid Dense Clusters and Crystal Nucleation

C. Betzel, S. Falke, H. Brognaro, 2018, Encyclopedia of Analytical Chemistry.

First look at RNA in L-configuration.

M. Vallazza, M. Perbandt, C. Betzel, 2004, Acta crystallographica. Section D, Biological crystallography.

The crystal structure of a Thermus thermophilus tRNA(Gly) acceptor stem microhelix at 1.6 Å resolution.

C. Betzel, V. Erdmann, D. Oberthür, 2011, Biochemical and biophysical research communications.

Crystallization and preliminary X-ray diffraction data of an LNA 7-mer duplex derived from a ricin aptamer.

C. Betzel, V. Erdmann, D. Oberthuer, 2009, Acta crystallographica. Section F, Structural biology and crystallization communications.

The 1.2A crystal structure of an E. coli tRNASer)acceptor stem microhelix reveals two magnesium binding sites.

M. Perbandt, C. Betzel, V. Erdmann, 2009, Biochemical and biophysical research communications.

Escherichia coli tRNA(Arg) acceptor-stem isoacceptors: comparative crystallization and preliminary X-ray diffraction analysis.

M. Perbandt, C. Betzel, V. Erdmann, 2009, Acta crystallographica. Section F, Structural biology and crystallization communications.

X-ray diffraction analysis of a human tRNA(Gly) acceptor-stem microhelix isoacceptor at 1.18 A resolution.

M. Perbandt, C. Betzel, V. Erdmann, 2009, Acta crystallographica. Section F, Structural biology and crystallization communications.

Cocrystallizing natural RNA with its unnatural mirror image: biochemical and preliminary X-ray diffraction analysis of a 5S rRNA A-helix racemate.

M. Perbandt, C. Betzel, V. Erdmann, 2007, Acta crystallographica. Section F, Structural biology and crystallization communications.

Proteomic analysis of the rare Uracoan rattlesnake Crotalus vegrandis venom: Evidence of a broad arsenal of toxins.

C. Betzel, H. Schlüter, P. Spencer, 2015, Toxicon : official journal of the International Society on Toxinology.

Crystal Structure of a Complex Formed between a Snake Venom Phospholipase A2 and a Potent Peptide Inhibitor Phe-Leu-Ser-Tyr-Lys at 1.8 Å Resolution*

M. Perbandt, C. Betzel, T. Singh, 2002, The Journal of Biological Chemistry.

In cellulo crystallization of Trypanosoma brucei IMP dehydrogenase enables the identification of genuine co-factors

Garth J. Williams, H. Chapman, A. Barty, 2020, Nature Communications.

Structure of a serine protease proteinase K from Tritirachium album limber at 0.98 A resolution.

M. Perbandt, C. Betzel, T. Singh, 2001, Biochemistry.

Structure of the Major Cytosolic Glutathione S-Transferase from the Parasitic Nematode Onchocerca volvulus*

M. Perbandt, C. Betzel, E. Liebau, 2005, Journal of Biological Chemistry.

Crystal structures of the alkaline proteases savinase and esperase from Bacillus lentus.

C. Betzel, K. Wilson, S. Branner, 1996, Advances in experimental medicine and biology.

Crystal structure of a complex between thermitase from Thermoactinomyces vulgaris and the leech inhibitor eglin

C. Betzel, Z. Dauter, K. Wilson, 1988, FEBS letters.

Crystal structures of the complexes of a group IIA phospholipase A2 with two natural anti‐inflammatory agents, anisic acid, and atropine reveal a similar mode of binding

M. Perbandt, C. Betzel, Sujata Sharma, 2006, Proteins.

Crystal structure of an extracellular superoxide dismutase from Onchocerca volvulus and implications for parasite-specific drug development

M. Perbandt, C. Betzel, E. Liebau, 2022, Acta crystallographica. Section F, Structural biology communications.

Isolation, identification and functional profile of excretory-secretory peptides from Onchocerca ochengi.

M. Perbandt, C. Betzel, H. Schlüter, 2015, Acta tropica.

Structure of the extracellular glutathione S-transferase OvGST1 from the human pathogenic parasite Onchocerca volvulus.

M. Perbandt, C. Betzel, E. Liebau, 2008, Journal of molecular biology.

MRSA infections: from classical treatment to suicide drugs.

C. Betzel, C. Wrenger, C. Pereira, 2014, Current medicinal chemistry.

Venom peptide analysis of Vipera ammodytes meridionalis (Viperinae) and Bothrops jararacussu (Crotalinae) demonstrates subfamily-specificity of the peptidome in the family Viperidae.

C. Betzel, H. Schlüter, D. Georgieva, 2011, Molecular bioSystems.

Lysine as a Critical Amino Acid for IgE Binding in Phl p 5b C Terminus

C. Betzel, E. Hofmann, A. Bufe, 2006, International Archives of Allergy and Immunology.

High resolution structures of Plasmodium falciparum GST complexes provide novel insights into the dimer-tetramer transition and a novel ligand-binding site.

M. Perbandt, C. Betzel, E. Liebau, 2015, Journal of structural biology.

Structure of the Lassa Virus Nucleoprotein Revealed by X-ray Crystallography, Small-angle X-ray Scattering, and Electron Microscopy*

M. Perbandt, C. Betzel, H. Stark, 2011, The Journal of Biological Chemistry.

Rapid and efficient room-temperature serial synchrotron crystallography using the CFEL TapeDrive

M. Aepfelbacher, H. Chapman, M. Perbandt, 2022, IUCrJ.

Three-Dimensional Modelling of Honeybee Venom Allergenic Proteases: Relation to Allergenicity

C. Betzel, D. Georgieva, R. Arni, 2011, Zeitschrift fur Naturforschung. C, Journal of biosciences.

Three-dimensional model of the honeybee venom allergen Api m 7: structural and functional insights.

C. Betzel, D. Georgieva, Kerstin Greunke, 2010, Molecular bioSystems.

Room-temperature macromolecular serial crystallography using synchrotron radiation

Anton Barty, Mengning Liang, Henry N. Chapman, 2014, IUCrJ.

Megahertz serial crystallography

Steffen Hauf, Hans Fangohr, Marcin Sikorski, 2018, Nature Communications.

In vivo protein crystallization opens new routes in structural biology

Georg Weidenspointner, Heike Soltau, Anton Barty, 2012, Nature Methods.

Natively Inhibited Trypanosoma brucei Cathepsin B Structure Determined by Using an X-ray Laser

Anton Barty, Sébastien Boutet, Carl Caleman, 2013, Science.

The XBI BioLab for life science experiments at the European XFEL

Janos Hajdu, Petra Fromme, Poul Nissen, 2021, Journal of applied crystallography.

The first crystal structure of an RNA racemate.

M. Vallazza, M. Perbandt, L. DeLucas, 2006, Acta crystallographica. Section D, Biological crystallography.

Structural basis for branching‐enzyme activity of glycoside hydrolase family 57: Structure and stability studies of a novel branching enzyme from the hyperthermophilic archaeon Thermococcus Kodakaraensis KOD1

C. Betzel, T. Kanai, T. Imanaka, 2011, Proteins.

Structural insights into the catalytic mechanism of sphingomyelinases D and evolutionary relationship to glycerophosphodiester phosphodiesterases.

Christian Betzel, C. Betzel, R. Arni, 2006, Biochemical and biophysical research communications.

Atomic Structure and Biochemical Characterization of an RNA Endonuclease in the N Terminus of Andes Virus L Protein

C. Betzel, S. Günther, S. Cusack, 2016, PLoS pathogens.

Features of “All LNA” Duplexes Showing a New Type of Nucleic Acid Geometry

C. Betzel, A. Nitsche, D. Oberthür, 2012, Journal of nucleic acids.

The crystal structure of an ‘All Locked’ nucleic acid duplex

C. Betzel, V. Erdmann, J. Fürste, 2010, Nucleic acids research.

Comparative crystallization and preliminary X-ray diffraction studies of locked nucleic acid and RNA stems of a tenascin C-binding aptamer.

M. Perbandt, C. Betzel, V. Erdmann, 2006, Acta crystallographica. Section F, Structural biology and crystallization communications.

Structural changes of tRNA and 5S rRNA induced with magnesium and visualized with synchrotron mediated hydroxyl radical cleavage

J. Barciszewski, C. Betzel, V. Erdmann, 2004, Molecular Biology Reports.

Structure of an RNA duplex with an unusual G.C pair in wobble-like conformation at 1.6 A resolution.

M. Vallazza, M. Perbandt, C. Betzel, 2001, Acta crystallographica. Section D, Biological crystallography.

Structure of Free Thermus flavus 5 S rRNA at 1.3 nm Resolution from Synchrotron X-ray Solution Scattering*

M. Vallazza, M. Perbandt, C. Betzel, 2000, The Journal of Biological Chemistry.

Crystallization of engineered Thermus flavus 5S rRNA under earth and microgravity conditions.

M. Perbandt, K. Moore, L. DeLucas, 2000, Acta crystallographica. Section D, Biological crystallography.

Crystal structure of domain E of Thermus flavus 5S rRNA: a helical RNA structure including a hairpin loop

M. Perbandt, C. Betzel, V. Erdmann, 1998, FEBS letters.

Crystal structure of domain A of Thermus flavus 5S rRNA and the contribution of water molecules to its structure

C. Betzel, K. Wilson, R. Bald, 1994, FEBS letters.

Three-Dimensional Structures and Mechanisms of Snake Venom Serine Proteinases, Metalloproteinases, and Phospholipase A2s

C. Betzel, F. R. Moraes, M. Coronado, 2016 .

X-ray structure of lipoamide dehydrogenase from Azotobacter vinelandii determined by a combination of molecular and isomorphous replacement techniques.

G. Vriend, C. Betzel, R. Read, 1989, Journal of molecular biology.

The refined crystal structure of Pseudomonas putida lipoamide dehydrogenase complexed with NAD+ at 2.45 Å resolution

C. Betzel, W. Hol, G. Obmolova, 1992, Proteins.

Asp49 phospholipase A(2)-elaidoylamide complex: a new mode of inhibition.

C. Betzel, W. Rypniewski, D. Georgieva, 2004, Biochemical and biophysical research communications.

Structure of ThiM from Vitamin B1 biosynthetic pathway of Staphylococcus aureus – Insights into a novel pro-drug approach addressing MRSA infections

M. Perbandt, C. Betzel, D. Svergun, 2016, Scientific Reports.

SARS-CoV-2 papain-like protease PLpro in complex with natural compounds reveal allosteric sites for antiviral drug design

H. Chapman, M. Perbandt, C. Betzel, 2021, bioRxiv.

First structural evidence of a specific inhibition of phospholipase A2 by alpha-tocopherol (vitamin E) and its implications in inflammation: crystal structure of the complex formed between phospholipase A2 and alpha-tocopherol at 1.8 A resolution.

C. Betzel, T. Singh, P. Kaur, 2002, Journal of molecular biology.

A Giant Extracellular Matrix Binding Protein of Staphylococcus epidermidis Binds Surface-Immobilized Fibronectin via a Novel Mechanism

M. Christner, H. Rohde, M. Aepfelbacher, 2020, mBio.

Modeling of Oxidized PTH (oxPTH) and Non-oxidized PTH (n-oxPTH) Receptor Binding and Relationship of Oxidized to Non-Oxidized PTH in Children with Chronic Renal Failure, Adult Patients on Hemodialysis and Kidney Transplant Recipients

C. Betzel, T. Slowinski, A. Doyon, 2013, Kidney and Blood Pressure Research.

Elapid Snake Venom Analyses Show the Specificity of the Peptide Composition at the Level of Genera Naja and Notechis

C. Betzel, M. Kwiatkowski, H. Schlüter, 2014, Toxins.

Snake venomics of the Siamese Russell's viper (Daboia russelli siamensis) -- relation to pharmacological activities.

C. Betzel, N. Jehmlich, M. von Bergen, 2009, Journal of proteomics.

Peptide NMHRYPNQ of the cellular prion protein (PrP(C)) inhibits aggregation and is a potential key for understanding prion-prion interactions.

C. Betzel, B. Meyer, N. Jehmlich, 2009, Journal of Molecular Biology.

Comparative Analysis of the Human and Chicken Prion Protein Copper Binding Regions at pH 6.5*

M. Perbandt, C. Betzel, H. Kalbacher, 2005, Journal of Biological Chemistry.

A critical role of water in the specific cleavage of the anticodon loop of some eukaryotic methionine initiator tRNAs

J. Barciszewski, C. Betzel, V. Erdmann, 2003, Molecular Biology Reports.

Crystal structure of the peptidoglycan recognition protein at 1.8 A resolution reveals dual strategy to combat infection through two independent functional homodimers.

M. Perbandt, C. Betzel, Sujata Sharma, 2008, Journal of molecular biology.

Catalytic cleavage of HEAT and subsequent covalent binding of the tetralone moiety by the SARS-CoV-2 main protease

Diana C. F. Monteiro, H. Chapman, C. Betzel, 2020, bioRxiv.

Three‐dimensional structure of the Fab fragment of a neutralizing antibody to human rhinovirus serotype 2

C. Betzel, H. Auer, J. Tormo, 1992, Protein science : a publication of the Protein Society.

Crystallization of the major cytosolic glutathione S-transferase from Onchocerca volvulus.

M. Perbandt, C. Betzel, E. Liebau, 2004, Acta crystallographica. Section D, Biological crystallography.

Crystallization and preliminary X-ray diffraction studies of the glutathione S-transferase from Plasmodium falciparum.

M. Perbandt, C. Betzel, E. Liebau, 2003, Acta crystallographica. Section D, Biological crystallography.

Crystallographic studies of Savinase, a subtilisin-like proteinase, at pH 10.5.

C. Betzel, K. Wilson, G. Lange, 1994, European journal of biochemistry.

The structure of a native l-amino acid oxidase, the major component of the Vipera ammodytes ammodytes venomic, reveals dynamic active site and quaternary structure stabilization by divalent ions.

C. Betzel, M. Murakami, D. Georgieva, 2011, Molecular bioSystems.

Crystal structure of a novel myotoxic Arg49 phospholipase A2 homolog (zhaoermiatoxin) from Zhaoermia mangshanensis snake venom: insights into Arg49 coordination and the role of Lys122 in the polarization of the C-terminus.

C. Betzel, R. Arni, U. Kuch, 2008, Toxicon : official journal of the International Society on Toxinology.

Crystallization and preliminary X-ray diffraction studies of an alkaline protease from Bacillus lentus.

K S Wilson, Z Dauter, C. Betzel, 1988, Journal of molecular biology.

Detection of native peptides as potent inhibitors of enzymes

C. Betzel, Sujata Sharma, M. N. Gupta, 2005, The FEBS journal.

X-ray screening identifies active site and allosteric inhibitors of SARS-CoV-2 main protease

Diana C. F. Monteiro, H. Chapman, C. Betzel, 2021, Science.

Tracing transport of protein aggregates in microgravity versus unit gravity crystallization

L. DeLucas, C. Betzel, S. Falke, 2022, NPJ microgravity.

Insights into metal ion binding in phospholipases A2: ultra high-resolution crystal structures of an acidic phospholipase A2 in the Ca2+ free and bound states.

C. Betzel, M. Murakami, R. Arni, 2006, Biochimie.

Impact of methionine oxidation as an initial event on the pathway of human prion protein conversion

C. Betzel, L. Redecke, U. Borgmeyer, 2013, Prion.

Protein Crystallization in Space: Early Successes and Drawbacks in the German Space Life Sciences Program

Günter Ruyters, Christian Betzel, C. Betzel, 2017 .

Reliably distinguishing protein nanocrystals from amorphous precipitate by means of depolarized dynamic light scattering

M. Perbandt, C. Betzel, R. Reimer, 2015 .

The secreted form of the epidermal growth factor receptor. Characterization and crystallization of the receptor-ligand complex.

C. Betzel, N. Günther, W. Weber, 1990, The Journal of biological chemistry.

Crystal structure of a mirror-image L-RNA aptamer (Spiegelmer) in complex with the natural L-protein target CCL2

C. Betzel, S. Klußmann, S. Falke, 2015, Nature Communications.

Crystal Structure of human seminal lactoferrin at 3.4A resolution

C. Betzel, T. Singh, P. Kaur, 2003 .

Crystal structure of human seminal diferric lactoferrin at 3.4 Å resolution

C. Betzel, Sujata Sharma, T. Singh, 2003 .

Structure of mistletoe lectin I from Viscum album in complex with the phytohormone zeatin.

J. Barciszewski, C. Betzel, A. Meyer, 2008, Biochimica et biophysica acta.

Subtilisin enzymes : practical protein engineering

C. Betzel, R. Bott, 1996 .

Substrate Specificity of the Highly Alkalophilic Bacterial Proteinase Esperase: Relation to the X-Ray Structure

C. Betzel, D. Georgieva, N. Genov, 2001, Current Microbiology.

X-ray characterization of single crystals of the reaction center I of water splitting photosynthesis

C. Betzel, Z. Dauter, W. Saenger, 1988 .

Chapter 696 – Thermitase

C. Betzel, 2013 .

Enhancement of enzyme activity through three-phase partitioning: crystal structure of a modified serine proteinase at 1.5 A resolution.

C. Betzel, T. Singh, I. Roy, 2001, Protein engineering.

Solution Structures and Dynamic Assembly of the 24-Meric Plasmodial Pdx1–Pdx2 Complex

C. Betzel, C. Wrenger, H. Andaleeb, 2020, International journal of molecular sciences.

Cloning, Recombinant Expression and Characterization of Wild Type‐105‐Trp‐Calmodulin of the Green Alga Mougeotia scalaris

M. Perbandt, C. Betzel, C. Zörb, 1998 .

Systematic analysis of protein–detergent complexes applying dynamic light scattering to optimize solutions for crystallization trials

C. Betzel, H. Brognaro, K. Brillet, 2015, Acta crystallographica. Section F, Structural biology communications.

Sequence-induced trimerization of phospholipase A2: structure of a trimeric isoform of PLA2 from common krait (Bungarus caeruleus) at 2.5 A resolution.

C. Betzel, Sujata Sharma, T. Singh, 2005, Acta crystallographica. Section F, Structural biology and crystallization communications.

Crystal structure of a carbohydrate induced homodimer of phospholipase A2 from Bungarus caeruleus at 2.1A resolution.

C. Betzel, Sujata Sharma, T. Singh, 2004, Journal of structural biology.

Analysis of self-assembly of S-layer protein slp-B53 from Lysinibacillus sphaericus

C. Betzel, D. Svergun, Jun Liu, 2016, European Biophysics Journal.

Thermitase and proteinase K: a comparison of the refined three-dimensional structures of the native enzymes.

C. Betzel, K. Wilson, W. Saenger, 1990, Protein engineering.

Synchrotron X-ray data collection and restrained least-squares refinement of the crystal structure of proteinase K at 1.5 A resolution.

C. Betzel, W. Saenger, G. Pal, 1988, Acta Crystallographica Section B Structural Science.

Structure of a novel ribosome-inactivating protein from a hemi-parasitic plant inhabiting the northwestern Himalayas.

C. Betzel, A. S. Ethayathulla, T. Singh, 2004, Acta crystallographica. Section D, Biological crystallography.

Crystal structure of a sigma 28-regulated non-flagella virulence protein from campylobacter jejuni

E. Goldsmith, M. Perbandt, C. Betzel, 2008 .

Trypanosoma brucei ATG8: Structural insights into autophagic-like mechanisms in protozoa

M. Perbandt, C. Betzel, M. Duszenko, 2009, Autophagy.

Molecular characterization of a ghrelin-l-aptamer complex

M. Perbandt, C. Betzel, C. Schmidt, 2020 .

Spider's venom phospholipases D: A structural review.

C. Betzel, K. Ullah, A. Ullah, 2018, International journal of biological macromolecules.

A TIM barrel protein without enzymatic activity? Crystal‐structure of narbonin at 1.8 Å resolution

C. Betzel, Z. Dauter, M. Hennig, 1992, FEBS letters.

Structural basis of phospholipase A2 inhibition for the synthesis of prostaglandins by the plant alkaloid aristolochic acid from a 1.7 A crystal structure.

C. Betzel, T. Singh, P. Kaur, 2002, Biochemistry.

Crystallization of proteins under microgravity

C. Betzel, G. Schulz, C. Müller, 1989 .

Initiation and modulation of Tau protein phase separation by the drug suramin

C. Betzel, E. Mandelkow, H. Brognaro, 2023, Scientific Reports.

Structural studies on the cobra venom factor: isolation, purification, crystallization and preliminary crystallographic analysis.

C. Betzel, T. Singh, T. Jabeen, 2001, Acta crystallographica. Section D, Biological crystallography.

Heating Affects Structure, Enterocyte Adsorption and Signalling, As Well as Immunogenicity of the Peanut Allergen Ara h 2.

C. Betzel, H. Sampson, D. Oberthuer, 2011, The open allergy journal.

Polysaccharide binding sites in hyaluronate lyase – crystal structures of native phage–encoded hyaluronate lyase and its complexes with ascorbic acid and lactose

Christian Betzel, Punit Kaur, M. Perbandt, 2009, The FEBS journal.

Protein C Activators from Snake Venom

C. Betzel, R. Arni, M. Murakami, 2013 .

Structure of the functional domain of the major grass-pollen allergen Phlp 5b.

C. Betzel, B. Lindner, K. Rajashankar, 2002, Acta crystallographica. Section D, Biological crystallography.

Crystal structure of jacalin-T-antigen complex

S. Banumathi, C. Betzel, A. Surolia, 2002 .

Crystal structure of human seminal diferric lactoferrin at 3.4 Angstrom resolution.

C. Betzel, Sujata Sharma, T. Singh, 2003, Indian Journal of Biochemistry & Biophysics.

Crystal structure of a complex formed between proteolytically‐generated lactoferrin fragment and proteinase K

C. Betzel, Sujata Sharma, T. Singh, 1998, Proteins.

Structure of the neurotoxic complex vipoxin at 1.4 A resolution.

S. Banumathi, C. Betzel, T. Singh, 2001, Acta crystallographica. Section D, Biological crystallography.

A multi-channel in situ light scattering instrument utilized for monitoring protein aggregation and liquid dense cluster formation

C. Betzel, S. Falke, H. Brognaro, 2019, Heliyon.

Monitoring and Scoring Counter-Diffusion Protein Crystallization Experiments in Capillaries by in situ Dynamic Light Scattering

C. Betzel, D. Oberthuer, A. Meyer, 2012, PloS one.

.beta.-D-Cellotetraose Hemihydrate as a Structural Model for Cellulose II. An X-ray Diffraction Study

C. Betzel, W. Saenger, N. Krauß, 1995 .

Mercury induced modifications in the stereochemistry of the active site through Cys-73 in a serine protease--crystal structure of the complex of a partially modified proteinase K with mercury at 1.8 A resolution.

K. Moore, L. DeLucas, C. Betzel, 2001, Indian journal of biochemistry & biophysics.

Crystal structure of a dimeric Ser49- PLA₂-like myotoxic component of the Vipera ammodytes meridionalis venomics reveals determinants of myotoxicity and membrane damaging activity.

C. Betzel, M. Coronado, D. Oberthür, 2012, Molecular bioSystems.

Atomic structure of the Serratia marcescens endonuclease at 1.1 A resolution and the enzyme reaction mechanism.

M. Perbandt, C. Betzel, V. Levdikov, 2000, Acta crystallographica. Section D, Biological crystallography.

The sequence and X-ray structure of the trypsin from Fusarium oxysporum.

C. Betzel, Z. Dauter, S. Hastrup, 1993, Protein engineering.

Structure and dynamics of UBA5-UFM1 complex formation showing new insights in the UBA5 activation mechanism.

M. Perbandt, C. Betzel, E. Liebau, 2021, Journal of structural biology.

Structure of SARS-CoV-2 papain-like protease PLpro reveals a framework for antiviral inhibitor design

C. Betzel, A. Meents, S. Falke, 2021, Acta Crystallographica Section A Foundations and Advances.

Hydrogen bonding patterns and dynamics in the hydration of biological macromolecules

C. Betzel, B. Hingerty, W. Saenger, 1985, Journal of Biosciences.

Subtilisin BPN' at 1.6 A resolution: analysis for discrete disorder and comparison of crystal forms.

C. Betzel, G. Gilliland, R. Bott, 1995, Acta crystallographica. Section D, Biological crystallography.

Crystallization and X-ray diffraction data of Thermus flavus 5S rRNA helices

M. Perbandt, C. Betzel, V. Erdmann, 2001 .

High resolution structure of streptavidin in complex with a novel high affinity peptide tag mimicking the biotin binding motif

M. Vallazza, M. Perbandt, C. Betzel, 2007, Proteins.

Structural Features of a Full-Length Ubiquitin Ligase Responsible for the Formation of Patches at the Plasma Membrane

C. Betzel, S. Hoth, S. Falke, 2021, International journal of molecular sciences.

Structure of the proteinase inhibitor eglin c with hydrolysed reactive centre at 2.0 Å resolution

Christian Betzel, Zbigniew Dauter, Jorge Navaza, 1993, FEBS letters.

Structural characterization of beta-sheeted oligomers formed on the pathway of oxidative prion protein aggregation in vitro.

C. Betzel, E. Mandelkow, P. Konarev, 2007, Journal of structural biology.

Purification, crystallization and preliminary X-ray study of the fungal laccase from Cerrena maxima

C. Betzel, G. Kachalova, V. Lamzin, 2006, Acta crystallographica. Section F, Structural biology and crystallization communications.

Light Microscopy and Dynamic Light Scattering to Study Liquid-Liquid Phase Separation of Tau Proteins In Vitro.

C. Betzel, E. Mandelkow, Susanne Wegmann, 2023, Methods in molecular biology.

Wucherria bancrofti glutathione S-Transferase: Insights into the 2.3 Å resolution X-ray structure and function, a therapeutic target for human lymphatic filariasis.

M. Perbandt, C. Betzel, Sakthi D Moorthy, 2018, Biochemical and biophysical research communications.

Effects of forced solution flow on lysozyme crystal growth

C. Betzel, K. Dierks, D. Oberthür, 2010 .

Investigations on the synthesis and crystallization of hydroxyapatite at low temperature.

C. Betzel, S. Kalkura, M. Ashok, 2004, Bio-medical materials and engineering.

A Comparative Structure–Function Analysis and Molecular Mechanism of Action of Endonucleases from Serratia marcescens and Physarum polycephalum

M. Perbandt, C. Betzel, E. Blagova, 2004, Russian Journal of Bioorganic Chemistry.

Highlight: Of Systems and Structures

C. Betzel, M. Wilmanns, D. Heinz, 2010, Biological chemistry.

Latest methods of fluorescence-based protein crystal identification

C. Betzel, A. Meyer, M. Pusey, 2015, Acta crystallographica. Section F, Structural biology communications.

Structural and Functional Analysis of Pyrimidine Nucleoside Phosphorylases of the NP-I and NP-II Families in Complexes with 6-Methyluracil

C. Betzel, A. Mironov, V. Balaev, 2018, Crystallography reports (Print).

Sodium carbonate heptahydrate

C. Betzel, W. Saenger, D. Loewus, 1982 .

Crystal structure of pyrimidine-nucleoside phosphorylase from Bacillus subtilis in complex with imidazole and sulfate.

C. Betzel, V. Balaev, I. Prokofev, 2018, Acta crystallographica. Section F, Structural biology communications.

Enzymatic Activity and Inhibition of the Neurotoxic Complex Vipoxin from the Venom of Vipera ammodytes meridionalis

M. Perbandt, C. Betzel, K. Rajashankar, 2002, Zeitschrift fur Naturforschung. C, Journal of biosciences.

Optimization of protein crystallization: the OptiCryst project

C. Betzel, R. Hilgenfeld, N. Chayen, 2011 .

Structure of the heterodimeric neurotoxic complex viperotoxin F (RV-4/RV-7) from the venom of Vipera russelli formosensis at 1.9 A resolution.

I. Tsai, S. Banumathi, M. Perbandt, 2003, Acta crystallographica. Section D, Biological crystallography.

Purine activity of RNase T1RV is further improved by substitution of Trp59 by tyrosine.

M. Perbandt, C. Betzel, U. Hahn, 2005, Biochemical and biophysical research communications.

Three-dimensional Structure of a Kunitz-type Inhibitor in Complex with an Elastase-like Enzyme*

M. Perbandt, C. Betzel, U. Hahn, 2015, The Journal of Biological Chemistry.

Exploring Nucleation Pathways in Distinct Physicochemical Environments Unveiling Novel Options to Modulate and Optimize Protein Crystallization

C. Betzel, H. Brognaro, Mengying Wang, 2022, Crystals.

Crystallographic structure analysis of urease from Jack bean (Canavalia ensiformis) at 1.49 A Resolution

S. Banumathi, C. Betzel, M. Choudhary, 2012 .

Enzymatic toxins from snake venom: structural characterization and mechanism of catalysis

C. Betzel, Sujata Sharma, R. Kini, 2011, The FEBS journal.

Towards the 3D Structure of 5s rRNA

M. Perbandt, C. Betzel, V. Erdmann, 1999 .

Helmholtz-Zentrum Dresden-Rossendorf (HZDR) Analysis of self‐assembly of S‐layer protein slp‐B53 from Lysinibacillus sphaericus

C. Betzel, D. Svergun, Jun Liu, 2020 .

The Seryl-tRNA synthetase/tRNASer acceptor stem interface is mediated via a specific network of water molecules.

C. Betzel, V. Erdmann, D. Oberthuer, 2011, Biochemical and biophysical research communications.

tRNASer acceptor stem: conformation and hydration of a microhelix in a crystal structure at 1.8 A resolution.

C. Betzel, V. Erdmann, J. Fürste, 2007, Acta crystallographica. Section D, Biological crystallography.

Introduction to selected articles from the 15th ICCBM

C. Betzel, J. Mesters, H. Einspahr, 2015, Acta crystallographica. Section F, Structural biology communications.

CogiTx1: A novel subtilisin a inhibitor isolated from the sea anemone Condylactis gigantea belonging to the defensin 4 protein family.

C. Betzel, J. Lorenzo, L. Álvarez-Lajonchère, 2023, Biochimie.

Structure-function relationships in the neurotoxin Vipoxin from the venom of Vipera ammodytes meridionalis.

C. Betzel, K. Rajashankar, D. Georgieva, 2003, Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.

Structural Dynamics and Perspectives of Vitamin B6 Biosynthesis Enzymes in Plasmodium: Advances and Open Questions

C. Betzel, C. Wrenger, N. Ullah, 2021, Frontiers in Cellular and Infection Microbiology.

Multimodal multiphoton microscopy for protein crystal detection based on two-color ultrafast fiber laser source

C. Betzel, F. Kärtner, G. Chang, 2021, 2021 Conference on Lasers and Electro-Optics (CLEO).

The crystal structure of a Thermus thermophilus tRNA(Gly) acceptor stem microhelix at 1.6 Å resolution.

C. Betzel, J. Fürste, C. Förster, 2011, Biochemical and biophysical research communications.

Current Research in Photosynthesis

C. Betzel, Z. Dauter, W. Saenger, 1990, Springer Netherlands.

Calpeptin is a potent cathepsin inhibitor and drug candidate for SARS-CoV-2 infections

C. Betzel, C. Wrenger, A. Meents, 2023, Communications biology.

Isolation, identification and functional profile of excretory-secretory peptides from Onchocerca ochengi.

M. Perbandt, C. Betzel, H. Schlüter, 2015, Acta tropica.

Impact of methionine oxidation as an initial event on the pathway of human prion protein conversion

C. Betzel, L. Redecke, U. Borgmeyer, 2013, Prion.

Contributory presentations/posters

Diederichs, Bosco K. Ho, Hironori K. Nakamura, 1999, Journal of Biosciences.

Crystallisation under microgravity of mistletoe lectin I from Viscum album with adenine monophosphate and the crystal structure at 1.9 A resolution.

L. DeLucas, C. Betzel, L DeLucas, 2002, Acta crystallographica. Section D, Biological crystallography.

Two variants of the major serine protease inhibitor from the sea anemone Stichodactyla helianthus, expressed in Pichia pastoris.

C. Betzel, U. Hahn, R. García-Fernández, 2016, Protein expression and purification.

Sequence-induced trimerization of phospholipase A2: structure of a trimeric isoform of PLA2 from common krait (Bungarus caeruleus) at 2.5 A resolution.

C. Betzel, Sujata Sharma, T. Singh, 2005, Acta crystallographica. Section F, Structural biology and crystallization communications.