B. Frenkel

发表

Gillian H. Little, G. Coetzee, H. Noushmehr, 2011 .

Peripheral cannabinoid receptor, CB2, regulates bone mass.

B. Frenkel, A. Zimmer, R. Mechoulam, 2006, Proceedings of the National Academy of Sciences of the United States of America.

Expression of Cell Cycle Regulatory Factors in Differentiating Osteoblasts: Postproliferative Up-Regulation of Cyclins B and E

R. Schlegel, B. Frenkel, G. Stein, 1995 .

Dependence of Castration‐Resistant Prostate Cancer (CRPC) Stem Cells on CRPC‐Associated Fibroblasts

Chun-Peng Liao, P. Roy-Burman, B. Frenkel, 2014, Journal of cellular physiology.

A novel bone morphogenetic protein signaling in heterotypic cell interactions in prostate cancer.

Chun-Peng Liao, P. Roy-Burman, B. Frenkel, 2008, Cancer research.

Glucocorticoids Hijack Runx2 to Stimulate Wif1 for Suppression of Osteoblast Growth and Differentiation

B. Frenkel, Meng Li, N. Chimge, 2017, Journal of cellular physiology.

Cells Capable of Bone Production Engraft from Whole Bone Marrow Transplants in Nonablated Mice

B. Frenkel, G. Stein, J. Lian, 1999, The Journal of experimental medicine.

Glucocorticoids inhibit osteocalcin transcription in osteoblasts by suppressing Egr2/Krox20-binding enhancer.

B. Frenkel, Arvinder Khokhar, N. Leclerc, 2005, Arthritis and rheumatism.

Bone Morphogenetic Protein‐2 Restores Mineralization in Glucocorticoid‐Inhibited MC3T3‐E1 Osteoblast Cultures

B. Frenkel, C. Luppen, A. Boskey, 2003, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Roles of transactivating functions 1 and 2 of estrogen receptor-α in bone

B. Frenkel, P. Chambon, K. Sjögren, 2011, Proceedings of the National Academy of Sciences.

A Novel Regulatory Role for Stromal-derived Factor-1 Signaling in Bone Morphogenic Protein-2 Osteogenic Differentiation of Mesenchymal C2C12 Cells*

B. Frenkel, C. Blobel, O. Boachie-Adjei, 2007, Journal of Biological Chemistry.

Species-specific glucocorticoid and 1,25-dihydroxyvitamin D responsiveness in mouse MC3T3-E1 osteoblasts: dexamethasone inhibits osteoblast differentiation and vitamin D down-regulates osteocalcin gene expression.

B. Frenkel, G. Stein, J. Lian, 1997, Endocrinology.

Estrogens and selective estrogen receptor modulators differentially antagonize Runx2 in ST2 mesenchymal progenitor cells

Dustin E. Schones, B. Frenkel, J. Katzenellenbogen, 2018, The Journal of Steroid Biochemistry and Molecular Biology.

Gene expression profiling of glucocorticoid-inhibited osteoblasts.

B. Frenkel, J. Hacia, C. Luppen, 2004, Journal of molecular endocrinology.

Krox20/EGR2 deficiency accelerates cell growth and differentiation in the monocytic lineage and decreases bone mass.

S. K. Baniwal, B. Frenkel, Y. Gabet, 2010, Blood.

Glucocorticoids Antagonize RUNX2 During Osteoblast Differentiation in Cultures of ST2 Pluripotent Mesenchymal Cells

S. K. Baniwal, B. Frenkel, Anthony Martin, 2014, Journal of cellular biochemistry.

Brief Bone Morphogenetic Protein 2 Treatment of Glucocorticoid-inhibited MC3T3-E1 Osteoblasts Rescues Commitment-associated Cell Cycle and Mineralization without Alteration of Runx2*

B. Frenkel, A. Barski, C. Luppen, 2003, Journal of Biological Chemistry.

Arginine methylation of R81 in Smad6 confines BMP-induced Smad1 signaling

B. Frenkel, Jian Xu, Hong-Hui Sun, 2021, The Journal of biological chemistry.

Inhibition of AR‐mediated transcription by binding of Oct1 to a motif enriched in AR‐occupied regions

G. Coetzee, B. Frenkel, L. Jia, 2009, The Prostate.

Opposing effects of glucocorticoids and Wnt signaling on Krox20 and mineral deposition in osteoblast cultures

B. Frenkel, N. Leclerc, Dilan B Samarawickrama, 2008, Journal of cellular biochemistry.

Postproliferative Up-Regulation of Cyclins B and E1

R. Schlegel, B. Frenkel, G. Stein, 2006 .

Expression of Cell Cycle Regulatory Factors in Differentiating Osteoblasts : Postproliferative Up-Regulation of Cyclins B and E 1

R. Schlegel, B. Frenkel, G. Stein, 2006 .

Repression of Runx2 by androgen receptor (AR) in osteoblasts and prostate cancer cells: AR binds Runx2 and abrogates its recruitment to DNA.

G. Coetzee, S. K. Baniwal, B. Frenkel, 2009, Molecular endocrinology.

Chromatin hyperacetylation abrogates vitamin D-mediated transcriptional upregulation of the tissue-specific osteocalcin gene in vivo.

B. Frenkel, G. Stein, J. Lian, 1999, Biochemistry.

AP-1 and vitamin D receptor (VDR) signaling pathways converge at the rat osteocalcin VDR element: requirement for the internal activating protein-1 site for vitamin D-mediated trans-activation.

B. Frenkel, G. Stein, J. Lian, 1999, Endocrinology.

Functional role for Sp1 in the transcriptional amplification of a cell cycle regulated histone H4 gene.

B. Frenkel, K. Wright, A. V. van Wijnen, 1995, Biochemistry.

Biosynthesis of Osteogenic Growth Peptide via Alternative Translational Initiation at AUG85 of Histone H4 mRNA*

B. Frenkel, G. Stein, Yu-Chen Chen, 1999, The Journal of Biological Chemistry.

Transforming growth factor-beta 1 responsiveness of the rat osteocalcin gene is mediated by an activator protein-1 binding site.

B. Frenkel, G. Stein, J. Lian, 1996, Endocrinology.

Basal and vitamin D-responsive activity of the rat osteocalcin promoter in stably transfected osteosarcoma cells: requirement of upstream sequences for control by the proximal regulatory domain.

B. Frenkel, G. Stein, J. Lian, 1996, Endocrinology.

Position and orientation-selective silencer in protein-coding sequences of the rat osteocalcin gene.

B. Frenkel, G. Stein, J. Lian, 1993, Biochemistry.

High-Throughput Screen for Inhibitors of Androgen Receptor-RUNX2 Transcriptional Regulation in Prostate Cancer

Gillian H. Little, B. Frenkel, Jeremy O. Jones, 2016, The Journal of Pharmacology and Experimental Therapeutics.

Leucine-rich amelogenin peptide induces osteogenesis by activation of the Wnt pathway.

B. Frenkel, Y. Zhou, M. Snead, 2009, Biochemical and biophysical research communications.

Inhibitory effects of the quinolone antibiotics trovafloxacin, ciprofloxacin, and levofloxacin on osteoblastic cells in vitro

B. Frenkel, P. Holtom, M. Patzakis, 2000, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

Glucocorticoids Inhibit Developmental Stage-specific Osteoblast Cell Cycle

G. Coetzee, B. Frenkel, C. Logg, 2000, The Journal of Biological Chemistry.

Post‐proliferative cyclin E‐associated kinase activity in differentiated osteoblasts: Inhibition by proliferating osteoblasts and osteosarcoma cells

B. Frenkel, G. Stein, J. Lian, 1997, Journal of cellular biochemistry.

GATA-6 mediates transcriptional activation of aquaporin-5 through interactions with Sp1.

B. Frenkel, E. Morrisey, D. Ann, 2008, American journal of physiology. Cell physiology.

Identification of novel androgen receptor target genes in prostate cancer

W. Gerald, G. Coetzee, B. Frenkel, 2007, Molecular Cancer.

Chromatin Remodeling and Androgen Receptor-Mediated Transcription

G. Coetzee, B. Frenkel, L. Jia, 2009 .

Genomic Androgen Receptor-Occupied Regions with Different Functions, Defined by Histone Acetylation, Coregulators and Transcriptional Capacity

G. Coetzee, B. Berman, B. Frenkel, 2008, PloS one.

Androgen receptor‐mediated repression of novel target genes

G. Coetzee, B. Frenkel, A. Barski, 2007, The Prostate.

Functional Enhancers at the Gene-Poor 8q24 Cancer-Linked Locus

D. Reich, P. Kantoff, G. Coetzee, 2009, PLoS genetics.

Absence of Ligand in Prostate Cancer Cells Androgen Receptor Enhancers in the Dynamic Nucleosome-Depleted Regions at

Peter A. Jones, B. Berman, B. Frenkel, 2014 .

Dynamic Nucleosome-Depleted Regions at Androgen Receptor Enhancers in the Absence of Ligand in Prostate Cancer Cells

Peter A. Jones, G. Coetzee, B. Berman, 2011, Molecular and Cellular Biology.

Prolactin-Induced Protein (PIP) Regulates Proliferation of Luminal A Type Breast Cancer Cells in an Estrogen-Independent Manner

S. K. Baniwal, B. Frenkel, N. Chimge, 2013, PloS one.

The 8q24 cancer risk variant rs6983267 demonstrates long-range interaction with MYC in colorectal cancer

Christopher A. Haiman, Li Jia, Matthew L. Freedman, 2009, Nature Genetics.

Identification of novel Runx2 targets in osteoblasts: Cell type‐specific BMP‐dependent regulation of Tram2

Andrés J. García, B. Frenkel, A. Barski, 2007, Journal of cellular biochemistry.

ChIP Display: novel method for identification of genomic targets of transcription factors.

B. Frenkel, A. Barski, 2004, Nucleic acids research.

Contextual effect of repression of bone morphogenetic protein activity in prostate cancer.

Chun-Peng Liao, B. Frenkel, H. Adisetiyo, 2013, Endocrine-related cancer.

The RUNX family in breast cancer: relationships with estrogen signaling

B. Frenkel, N. Chimge, N-O Chimge, 2013, Oncogene.

CLDN18.1 attenuates malignancy and related signaling pathways of lung adenocarcinoma in vivo and in vitro

B. Frenkel, N. Chimge, A. Firth, 2018, International journal of cancer.

Autophagic UVRAG Promotes UV-Induced Photolesion Repair by Activation of the CRL4(DDB2) E3 Ligase.

B. Frenkel, B. Oh, G. Aldrovandi, 2016, Molecular cell.

Activity of the osteocalcin promoter in skeletal sites of transgenic mice and during osteoblast differentiation in bone marrow-derived stromal cell cultures: effects of age and sex.

B. Frenkel, G. Stein, J. Lian, 1997, Endocrinology.

RUNX1 prevents oestrogen-mediated AXIN1 suppression and β-catenin activation in ER-positive breast cancer

Gillian H. Little, Dustin E. Schones, M. Ellis, 2016, Nature Communications.

ERK1/2-activated de Novo Mapkapk2 Synthesis Is Essential for Osteogenic Growth Peptide Mitogenic Signaling in Osteoblastic Cells*

B. Frenkel, I. Bab, Tommy Noh, 2005, Journal of Biological Chemistry.

A systematic approach to understand the functional consequences of non-protein coding risk regions

G. Coetzee, B. Frenkel, A. Tanay, 2010, Cell cycle.

Lef1 Haploinsufficient Mice Display a Low Turnover and Low Bone Mass Phenotype in a Gender- and Age-Specific Manner

B. Frenkel, J. Woodgett, R. Müller, 2009, PloS one.

Glucocorticoids Inhibit the Transcriptional Activity of LEF/TCF in Differentiating Osteoblasts in a Glycogen Synthase Kinase-3β-dependent and -independent Manner*

B. Frenkel, Elisheva Smith, 2005, Journal of Biological Chemistry.

Foxp2 inhibits Nkx2.1-mediated transcription of SP-C via interactions with the Nkx2.1 homeodomain.

B. Frenkel, E. Morrisey, D. Ann, 2008, American journal of respiratory cell and molecular biology.

Relationship between RUNX1 and AXIN1 in ER-negative versus ER-positive Breast Cancer

B. Frenkel, N. Chimge, Sara Ahmed-Alnassar, 2017, Cell cycle.

Osteoblast-specific gene expression after transplantation of marrow cells: implications for skeletal gene therapy.

B. Frenkel, G. Stein, J. Lian, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Estrogens antagonize RUNX2-mediated osteoblast-driven osteoclastogenesis through regulating RANKL membrane association.

P. Kostenuik, B. Frenkel, N. Chimge, 2015, Bone.

Modulation of Runx2 activity by estrogen receptor-alpha: implications for osteoporosis and breast cancer.

G. Coetzee, S. K. Baniwal, B. Frenkel, 2008, Endocrinology.

A composite intragenic silencer domain exhibits negative and positive transcriptional control of the bone-specific osteocalcin gene: promoter and cell type requirements.

B. Frenkel, G. Stein, J. Lian, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Diverse biological effect and Smad signaling of bone morphogenetic protein 7 in prostate tumor cells.

B. Frenkel, C. Zhong, Shangxin Yang, 2005, Cancer research.

Runx2 promotes both osteoblastogenesis and novel osteoclastogenic signals in ST2 mesenchymal progenitor cells

Parantu K. Shah, S. K. Baniwal, B. Frenkel, 2012, Osteoporosis International.

Regulation of breast cancer metastasis by Runx2 and estrogen signaling: the role of SNAI2

Gillian H. Little, S. K. Baniwal, B. Frenkel, 2011, Breast Cancer Research.

Runx2 transcriptome of prostate cancer cells: insights into invasiveness and bone metastasis

G. Coetzee, S. K. Baniwal, B. Frenkel, 2010, Molecular Cancer.

Location, location, (ChIP‐)location! Mapping chromatin landscapes one immunoprecipitation at a time

G. Coetzee, B. Berman, B. Frenkel, 2009, Journal of cellular biochemistry.

Leaky ribosomal scanning in mammalian genomes: significance of histone H4 alternative translation in vivo

B. Frenkel, J. Hacia, Mazen W. Karaman, 2005, Nucleic acids research.

Identification of transcription factor target genes by ChIP display.

B. Frenkel, A. Barski, Steven K Pregizer, 2008, Methods in molecular biology.

Glucocorticoid-Induced Osteoporosis.

B. Frenkel, J. Tuckermann, Wendy White, 2015, Advances in experimental medicine and biology.

Stage-specific expression of Dlx-5 during osteoblast differentiation: involvement in regulation of osteocalcin gene expression.

B. Frenkel, G. Stein, J. Lian, 1997, Molecular endocrinology.

BMP-2 vs. BMP-4 expression and activity in glucocorticoid-arrested MC3T3-E1 osteoblasts: Smad signaling, not alkaline phosphatase activity, predicts rescue of mineralization

B. Frenkel, C. Luppen, D. Mortlock, 2008, Growth factors.

Alterations in Brca1 expression in mouse ovarian granulosa cells have short-term and long-term consequences on estrogen-responsive organs

M. Pike, B. Frenkel, Y. Liu, 2012, Laboratory Investigation.

POTENTIAL CONSEQUENCES OF THE BRCA1 MUTATION CARRIER STATE ON ESTROGEN RESPONSIVE ORGANS

M. Pike, B. Frenkel, Y. Liu, 2012, Laboratory investigation; a journal of technical methods and pathology.

Interaction between bone marrow stromal cells and neuroblastoma cells leads to a VEGFA‐mediated osteoblastogenesis

S. K. Baniwal, B. Frenkel, R. Sposto, 2015, International journal of cancer.

Progressive recruitment of Runx2 to genomic targets despite decreasing expression during osteoblast differentiation

S. K. Baniwal, B. Frenkel, Xiting Yan, 2008, Journal of cellular biochemistry.

Runx2 controls a feed‐forward loop between androgen and prolactin‐induced protein (PIP) in stimulating T47D cell proliferation

Gillian H. Little, S. K. Baniwal, B. Frenkel, 2012, Journal of cellular physiology.

Opposing Effects of Runx2 and Estradiol on Breast Cancer Cell Proliferation: In Vitro Identification of Reciprocally Regulated Gene Signature Related to Clinical Letrozole Responsiveness

Simon G. Coetzee, M. Ellis, S. K. Baniwal, 2011, Clinical Cancer Research.

Differential effects of RUNX2 on the androgen receptor in prostate cancer: synergistic stimulation of a gene set exemplified by SNAI2 and subsequent invasiveness.

Gillian H. Little, Dustin E. Schones, S. Groshen, 2014, Cancer Research.

CB2 Cannabinoid Receptor Targets Mitogenic Gi Protein–Cyclin D1 Axis in Osteoblasts

B. Frenkel, A. Zimmer, R. Mechoulam, 2010, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Runx1-mediated regulation of osteoclast differentiation and function.

Hicham Drissi, S. K. Baniwal, B. Frenkel, 2014, Molecular endocrinology.

An enhancer from the 8 q 24 prostate cancer risk region is sufficient to direct reporter gene expression to a subset of prostate stem-like epithelial cells in transgenic mice

Chun-Peng Liao, S. Groshen, G. Coetzee, 2019 .

An enhancer from the 8q24 prostate cancer risk region is sufficient to direct reporter gene expression to a subset of prostate stem-like epithelial cells in transgenic mice

Chun-Peng Liao, S. Groshen, G. Coetzee, 2012, Disease Models & Mechanisms.

Estrogens and androgens inhibit association of RANKL with the pre‐osteoblast membrane through post‐translational mechanisms

B. Katzenellenbogen, B. Frenkel, J. Katzenellenbogen, 2017, Journal of cellular physiology.

Initial Characterization of Osteoblast Differentiation and Loss of RUNX2 Stability in the Newly Established SK11 Human Embryonic Stem Cell‐Derived Cell Line

Gillian H. Little, B. Frenkel, M. West, 2015, Journal of cellular physiology.

Estrogen receptor-α is required for the osteogenic response to mechanical loading in a ligand-independent manner involving its activation function 1 but not 2

Claes Ohlsson, Pierre Chambon, L. Lanyon, 2013, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Regulation of adult bone turnover by sex steroids

Claes Ohlsson, Omar Khalid, G. Coetzee, 2010, Journal of cellular physiology.

YY1 regulates vitamin D receptor/retinoid X receptor mediated transactivation of the vitamin D responsive osteocalcin gene.

B. Frenkel, G. Stein, J. Lian, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Predictive Biomarkers and Personalized Medicine Opposing Effects of Runx 2 and Estradiol on Breast Cancer Cell Proliferation : In Vitro Identi fi cation of Reciprocally Regulated Gene Signature Related to Clinical Letrozole Responsiveness

Simon G. Coetzee, M. Ellis, S. K. Baniwal, 2012 .

B. Frenkel, G. Stein, J. Lian, 1997, Endocrinology.

Developmentally regulated inhibition of cell cycle progression by glucocorticoids through repression of cyclin a transcription in primary osteoblast cultures

B. Frenkel, Y. Gabet, Tommy Noh, 2011, Journal of cellular physiology.

Role of apoptosis in glucocorticoid-induced osteoporosis and osteonecrosis.

B. Frenkel, C. Zalavras, M. Birnbaum, 2003, Critical reviews in eukaryotic gene expression.

Recruitment of coregulator G9a by Runx2 for selective enhancement or suppression of transcription

Gillian H. Little, S. K. Baniwal, B. Frenkel, 2012, Journal of cellular biochemistry.

Glucocorticoids Inhibit Cell Cycle Progression in Differentiating Osteoblasts via Glycogen Synthase Kinase-3β*

G. Coetzee, B. Frenkel, Elisheva Smith, 2002, The Journal of Biological Chemistry.

Requirement of distal and proximal promoter sequences for chromatin organization of the osteocalcin gene in bone‐derived cells

B. Frenkel, G. Stein, J. Lian, 1996 .

Hormone‐Independent Sexual Dimorphism in the Regulation of Bone Resorption by Krox20

B. Frenkel, Y. Gabet, T. Liron, 2019, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Requirement of distal and proximal promoter sequences for chromatin organization of the osteocalcin gene in bone-derived cells.

B. Frenkel, G. Stein, J. Lian, 1996, Journal of cellular biochemistry.

Androgen receptor responsive enhancers are flanked by consistently-positioned H3-acetylated nucleosomes

G. Coetzee, B. Berman, B. Frenkel, 2010, Cell cycle.

Leucine-rich amelogenin peptide induces osteogenesis by activation of the Wnt pathway.

B. Frenkel, M. Snead, R. Warotayanont, 2009, Biochemical and biophysical research communications.

The 8q24 cancer risk variant rs6983267 demonstrates long-range interaction with MYC in colorectal cancer

G. Coetzee, B. Frenkel, C. Haiman, 2009, Nature Genetics.

Modulation of Runx2 activity by estrogen receptor-alpha: implications for osteoporosis and breast cancer.

G. Coetzee, S. K. Baniwal, B. Frenkel, 2008, Endocrinology.

Osteoblast progenitors engraft from whole bone marrow transplants in nonablated mice

B. Frenkel, J. Lian, S. Nilsson, 1997 .

Molecular Cancer Identification of Novel Androgen Receptor Target Genes in Prostate Cancer

W. Gerald, G. Coetzee, B. Frenkel, 2022 .