C. Kappen

发表

Early evolutionary origin of major homeodomain sequence classes.

C. Kappen, K. Schughart, F. Ruddle, 1993, Genomics.

Promoter features related to tissue specificity as measured by Shannon entropy

M. Bucan, J. Schug, C. Kappen, 2005, Genome Biology.

Two steps in the evolution of Antennapedia-class vertebrate homeobox genes.

C Kappen, C. Kappen, K. Schughart, 1989, Proceedings of the National Academy of Sciences of the United States of America.

Altered Gene Expression in Diabetic Embryopathy: Multiple Pathways in Analysis and Interpretation

C. Kappen, J. Salbaum, C. Kruger, 2018 .

Analysis of Altered Gene Expression in Diabetic Embryopathy

C. Kappen, J. Salbaum, G. Pavlínková, 2010 .

Regulation of folate receptor 1 gene expression in the visceral endoderm.

C. Kappen, R. Finnell, J. Salbaum, 2009, Birth defects research. Part A, Clinical and molecular teratology.

Unbiased transcriptomic analysis of chondrocyte differentiation in a high-density cell culture model

C. Kappen, A. Limpach, C. Kruger, 2021, bioRxiv.

Sensitivity to Colon Carcinogenesis Folate Transport Gene Inactivation in Mice Increases Updated

C. Kappen, R. Finnell, J. Lupton, 2005 .

Vertebrate Hox Genes and Specializations in Mammals

C. Kappen, 2010 .

Traffic jam in the primitive streak: the role of defective mesoderm migration in birth defects.

C. Kappen, J. Salbaum, Nils J Herion, 2014, Birth defects research. Part A, Clinical and molecular teratology.

Papers from the 7th International Neural Tube Defects Conference.

C. Kappen, A. Molloy, 2012, Birth defects research. Part A, Clinical and molecular teratology.

Altered gene expression and spongiotrophoblast differentiation in placenta from a mouse model of diabetes in pregnancy

C. Kappen, J. Salbaum, G. Pavlínková, 2011, Diabetologia.

Transgenic Analyses Reveal Developmentally Regulated Neuron- and Muscle-specific Elements in the Murine Neurofilament Light Chain Gene Promoter*

C. Kappen, P. Yaworsky, D. Gardner, 1997, The Journal of Biological Chemistry.

Expression of Cartilage Developmental Genes in Hoxc8- and Hoxd4-Transgenic Mice

C. Kappen, C. Kruger, 2010, PloS one.

Modeling anterior development in mice: Diet as modulator of risk for neural tube defects

C. Kappen, 2013, American journal of medical genetics. Part C, Seminars in medical genetics.

Embryonic cell migratory capacity is impaired upon exposure to glucose in vivo and in vitro

C. Kappen, J. Salbaum, C. Kruger, 2018, Birth defects research.

Developmental characterization and chromosomal mapping of a LacZ transgene expressed in the mouse apical ectodermal ridge.

C. Kappen, D. Gardner, 2000, The Journal of experimental zoology.

Caudal dysgenesis in islet‐1 transgenic mice

C. Kappen, Y. L. Muller, P. Yaworsky, 2003, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Maternal diet modulates the risk for neural tube defects in a mouse model of diabetic pregnancy.

C. Kappen, J. Salbaum, C. Kruger, 2011, Reproductive toxicology.

Expression of folate pathway genes in the cartilage of Hoxd4 and Hoxc8 transgenic mice.

C. Kappen, C. Kruger, C. Talmadge, 2006, Birth defects research. Part A, Clinical and molecular teratology.

Gene expression in teratogenic exposures: a new approach to understanding individual risk.

C. Kappen, J. Salbaum, 2014, Reproductive toxicology.

Novel Mode of Defective Neural Tube Closure in the Non-Obese Diabetic (NOD) Mouse Strain

C. Kappen, J. Salbaum, C. Kruger, 2015, Scientific Reports.

Evolution of Hox genes.

F H Ruddle, J. W. Pendleton, C Kappen, 1994, Annual review of genetics.

Analysis of regulatory genes using the transgenic mouse system.

F H Ruddle, G W Byrne, C Kappen, 1991, Biotechnology.

Organization and Expression of Homeobox Genes in Mouse and Man a

C. Kappen, K. Schughart, F. Ruddle, 1989, Annals of the New York Academy of Sciences.

Folate supplementation in three genetic models: Implications for understanding folate‐dependent developmental pathways

C. Kappen, 2005, American journal of medical genetics. Part C, Seminars in medical genetics.

Normal proliferation and differentiation of Hoxc-8 transgenic chondrocytes in vitro

C. Kappen, S. Cormier, M. Mello, 2003, BMC Developmental Biology.

Maternal diet modulates placental nutrient transporter gene expression in a mouse model of diabetic pregnancy

C. Kappen, J. Salbaum, C. Kruger, 2019, PloS one.

Mammalian homeobox-containing genes: genome organization, structure, expression and evolution.

C. Kappen, K. Schughart, F. Ruddle, 1988, The British journal of cancer. Supplement.

In vivo generation and function of B cells in the presence of a monoclonal anti‐IgM antibody: implications for B cell tolerance

C. Kappen, K. Rajewsky, N. Yoshida, 1987, European journal of immunology.

Maternal Diet Modulates Placenta Growth and Gene Expression in a Mouse Model of Diabetic Pregnancy

C. Kappen, J. Salbaum, C. Kruger, 2012, PloS one.

Microarray Analysis of Defective Cartilage in Hoxc8- and Hoxd4-Transgenic Mice

C. Kappen, C. Kruger, 2010, Cartilage.

Morpholino-mediated knockdown in primary chondrocytes implicates Hoxc8 in regulation of cell cycle progression.

C. Kappen, J. Salbaum, C. Kruger, 2009, Bone.

Neural tube defect genes and maternal diabetes during pregnancy.

C. Kappen, J. Salbaum, 2010, Birth defects research. Part A, Clinical and molecular teratology.

Effect of maternal diabetes on the embryo, fetus, and children: congenital anomalies, genetic and epigenetic changes and developmental outcomes.

C. Kappen, E. Reece, E. A. Reece, 2015, Birth defects research. Part C, Embryo today : reviews.

Herpes simplex virus transcriptional activator VP16 is detrimental to preimplantation development in mice

C. Kappen, P. Yaworsky, Y. G. Yueh, 2000, Molecular reproduction and development.

Developmental consequences of in utero sodium arsenate exposure in mice with folate transport deficiencies.

C. Kappen, B. Wlodarczyk, R. Finnell, 2005, Toxicology and applied pharmacology.

Hox genes in the lung.

C. Kappen, 1996, American journal of respiratory cell and molecular biology.

Identification of regulatory elements in the Isl1 gene locus.

Claudia Kappen, C. Kappen, J. Salbaum, 2009, The International journal of developmental biology.

Maternal diabetes alters transcriptional programs in the developing embryo

C. Kappen, J. Salbaum, G. Pavlínková, 2009, BMC Genomics.

Molecular basis for skeletal variation: insights from developmental genetic studies in mice.

C. Kappen, R. Balling, R. Finnell, 2007, Birth defects research. Part B, Developmental and reproductive toxicology.

Developmental expression of the four plasma membrane calcium ATPase (Pmca) genes in the mouse.

C. Kappen, D. Zacharias, 1999, Biochimica et biophysica acta.

Wnt signaling in caudal dysgenesis and diabetic embryopathy.

C. Kappen, J. Salbaum, G. Pavlínková, 2008, Birth defects research. Part A, Clinical and molecular teratology.

Evidence for regulation of cartilage differentiation by the homeobox gene Hoxc-8.

C. Kappen, Y. G. Yueh, D. Gardner, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Disruption of the homeobox gene Hoxb‐6 in mice results in increased numbers of early erythrocyte progenitors

C. Kappen, 2000, American journal of hematology.

Developmental expression of the murine Prl-1 protein tyrosine phosphatase gene.

C. Kappen, C. Rundle, 1999, The Journal of experimental zoology.

Developmental Patterning as a Quantitative Trait: Genetic Modulation of the Hoxb6 Mutant Skeletal Phenotype

C. Kappen, 2016, PloS one.

Diabetic embryopathy: a role for the epigenome?

C. Kappen, J. Salbaum, 2011, Birth defects research. Part A, Clinical and molecular teratology.

Folate modulates Hox gene‐controlled skeletal phenotypes

C. Kappen, R. Finnell, J. Salbaum, 2004, Genesis.

09/15: Comparative genomics of a conserved chromosomal region associated with a complex human phenotype.

C. Kappen, J. Salbaum, 2001, Genomics.

Duplication of large genomic regions during the evolution of vertebrate homeobox genes.

C Kappen, C. Kappen, K. Schughart, 1989, Proceedings of the National Academy of Sciences of the United States of America.

The Homeodomain: An Ancient Evolutionary Motif in Animals and Plants

Claudia Kappen, C. Kappen, 2000, Comput. Chem..

Theoretical Approaches to the Analysis of Homeobox Gene Evolution

Claudia Kappen, C. Kappen, 1996, Comput. Chem..

Evolution of a regulatory gene family: HOM/HOX genes.

C. Kappen, F. Ruddle, 1993, Current opinion in genetics & development.

Evolutionary Analysis of Mammalian Homeobox Genes

C. Kappen, F. Ruddle, 1991 .

A map of VH genes located next to the DH region in the Igh locus of two congenic Igh‐recombinant mouse strains

C. Kappen, U. Krawinkel, C. Kolb, 1988, European journal of immunology.

Spatial and temporal regulation of alacZ reporter transgene in a binary transgenic mouse system

C. Kappen, F. Ruddle, G. Byrne, 2005, Transgenic Research.

Genetic and epigenomic footprints of folate.

C. Kappen, J. Salbaum, 2012, Progress in molecular biology and translational science.

High-Resolution Mapping of a Genetic Locus Regulating Preferential Carbohydrate Intake, Total Kilocalories, and Food Volume on Mouse Chromosome 17

C. Kappen, W. Johnson, J. Medrano, 2014, PloS one.

Homeobox gene repertoires: implications for the evolution of diversity

C. Kappen, 2005 .

Analysis of a complete homeobox gene repertoire: implications for the evolution of diversity.

C Kappen, C. Kappen, 2000, Proceedings of the National Academy of Sciences of the United States of America.

CSP-1/Dcpp salivary protein family gene locus, encoding a novel member of the Dcpp Identification of a human ortholog of the mouse

W. J. Brammar, C. Kappen, W. Johnson, 2015 .

Drastic change in idiotypic but not antigen-binding specificity of an antibody by a single amino-acid substitution

C. Kappen, K. Rajewsky, M. Brüggemann, 1985, Nature.

STRUCTURE OF MAMMALIAN HOMEOBOX GENES

C. Kappen, K. Schughart, F. Ruddle, 2006 .

Mutation at the folate receptor 4 locus modulates gene expression profiles in the mouse uterus in response to periconceptional folate supplementation.

C. Kappen, J. Salbaum, C. Kruger, 2013, Biochimica et biophysica acta.

Cloning and expression of nope, a new mouse gene of the immunoglobulin superfamily related to guidance receptors.

C. Kappen, J. Salbaum, 2000, Genomics.

Heterogeneity of neural progenitor cells revealed by enhancers in the nestin gene.

C. Kappen, P. Yaworsky, Claudia Kappen, 1999, Developmental biology.

Broad spectrum of CRISPR-induced edits in an embryonic lethal gene

C. Kappen, J. Salbaum, Kayla T B Fuselier, 2021, Scientific Reports.

Comparative genome annotation for mapping, prediction and discovery of genes

Claudia Kappen, J. Michael Salbaum, C. Kappen, 2003, 36th Annual Hawaii International Conference on System Sciences, 2003. Proceedings of the.

Responses of the embryonic epigenome to maternal diabetes.

C. Kappen, J. Salbaum, 2012, Birth defects research. Part A, Clinical and molecular teratology.

Gene expression in salivary glands: effects of diet and mouse chromosome 17 locus regulating macronutrient intake

C. Kappen, W. Johnson, Jacob Simon, 2015, Physiological reports.

Aberrant lipid accumulation in the mouse visceral yolk sac resulting from maternal diabetes and obesity

C. Kappen, J. Salbaum, Man Zhang, 2023, Frontiers in Cell and Developmental Biology.

Effects of Maternal Diabetes and Diet on Gene Expression in the Murine Placenta

C. Kappen, J. Salbaum, C. Kruger, 2022, Genes.

Nutrient Transporter Gene Expression in the Early Conceptus—Implications From Two Mouse Models of Diabetic Pregnancy

C. Kappen, J. Salbaum, S. Jones, 2022, Frontiers in Cell and Developmental Biology.

Transactivation of Hox gene expression in a VP16-dependent binary transgenic mouse system.

C. Kappen, C. Rundle, Y. G. Yueh, 1998, Biochimica et biophysica acta.

Mutation of a putative nuclear receptor binding site abolishes activity of the nestin midbrain enhancer.

Claudia Kappen, C. Kappen, Paul J Yaworsky, 2003, Biochimica et biophysica acta.

Content and Organization of the Immunoglobulin Heavy Chain Variable Gene Locus in the Mouse

C. Kappen, U. Krawinkel, T. Blankenstein, 1988 .

Transgenic studies on homeobox genes in nervous system development: spina bifida in Isl1 transgenic mice

C. Kappen, J. Salbaum, Y. L. Muller, 2013, Transgenic Research.

TCreERT2, a Transgenic Mouse Line for Temporal Control of Cre-Mediated Recombination in Lineages Emerging from the Primitive Streak or Tail Bud

Matthew J. Anderson, C. Kappen, M. Lewandoski, 2013, PloS one.

Identification of regulatory elements in the Isl1 gene locus.

C. Kappen, J. Salbaum, 2009, The International journal of developmental biology.

Regulation of folate receptor 1 gene expression in the visceral endoderm.

C. Kappen, R. Finnell, J. Salbaum, 2009, Birth defects research. Part A, Clinical and molecular teratology.

P261 Clinical outcomes of high-frequency repetitive transcranial magnetic stimulation (HF-rTMS) and electroconvulsive therapy (ECT) in the treatment of major depression. An overview of findings from meta-analyses

C. Kappen, C. Loo, K. Kedzior, 2017, Clinical Neurophysiology.

Differential responses to maternal diabetes in embryo and visceral yolk sac

C. Kappen, I. Sandovici, J. Salbaum, 2023, Frontiers in cell and developmental biology.

Papers from the 7th International Neural Tube Defects Conference.

C. Kappen, A. Molloy, 2012, Birth defects research. Part A, Clinical and molecular teratology.

Untargeted Pixel-by-Pixel Imaging of Metabolite Ratio Pairs as a Novel Tool for Biomedical Discovery in Mass Spectrometry Imaging

Weill Cornell Medicine, C. Kappen, J. Salbaum, 2024, bioRxiv.

Sensitivity to Colon Carcinogenesis Folate Transport Gene Inactivation in Mice Increases Updated

C. Kappen, R. Finnell, J. Lupton, 2005 .