S. Schaus

发表

Chemogenomic profiling on a genome-wide scale using reverse-engineered gene networks

J. Collins, D. Bernardo, M. Thompson, 2005, Nature Biotechnology.

Network-based prediction for sources of transcriptional dysregulation using latent pathway identification analysis

Lisa M. Christadore, E. Kolaczyk, S. Schaus, 2011, Proceedings of the National Academy of Sciences.

Organic Synthesis Toward Small-Molecule Probes and Drugs Special Feature: Discovery of new antimalarial chemotypes through chemical methodology and library development

Aaron B. Beeler, X. Su, S. Schaus, 2011 .

Synthesis of complex alkoxyamines using a polymer-supported N-hydroxyphthalimide

S. Schaus, J. Porco, Shun Su, 2004 .

A cycloisomerization/Friedel-Crafts alkylation strategy for the synthesis of pyrano[3,4-b]indoles.

S. Schaus, J. Porco, M. R. Medeiros, 2011, Organic letters.

Asymmetric allylboration of acyl imines catalyzed by chiral diols.

S. Schaus, Sha Lou, P. Moquist, 2007, Journal of the American Chemical Society.

Kinetic Resolution of Terminal Epoxides via Highly Regioselective and Enantioselective Ring Opening with TMSN3. An Efficient, Catalytic Route to 1,2-Amino Alcohols

S. Schaus, E. Jacobsen, J. Larrow, 1996 .

Highly selective hydrolytic kinetic resolution of terminal epoxides catalyzed by chiral (salen)Co(III) complexes. Practical synthesis of enantioenriched terminal epoxides and 1,2-diols.

Scott E Schaus, S. Schaus, A. Gould, 2002, Journal of the American Chemical Society.

The mechanism and an improved asymmetric allylboration of ketones catalyzed by chiral biphenols.

David S. Barnett, S. Schaus, P. Moquist, 2009, Angewandte Chemie.

Highly Selective Hydrolytic Kinetic Resolution of Terminal Epoxides Catalyzed by Chiral (Salen)CoIII Complexes. Practical Synthesis of Enantioenriched Terminal Epoxides and 1,2-Diols.

S. Schaus, A. Gould, M. Tokunaga, 2002 .

13. Brønsted Bases

S. Schaus, Amal Ting and, 2013 .

Highly diastereoselective asymmetric Mannich reactions of 1,3-dicarbonyls with acyl imines.

S. Schaus, Sha Lou, A. Ting, 2006, Organic letters.

Expansile Nanoparticles Encapsulate Factor Quinolinone Inhibitor 1 and Accumulate in Murine Liver upon Intravenous Administration.

S. Schaus, U. Hansen, M. Grinstaff, 2020, Biomacromolecules.

Pharmacological manipulation of LSF suppresses Wnt signaling and inhibits growth of allogeneic and syngeneic colon cancer xenografts.

S. Schaus, U. Hansen, Qing Zhao, 2022, The American journal of pathology.

Enantioselective addition of boronates to chromene acetals catalyzed by a chiral Brønsted acid/Lewis acid system.

S. Schaus, P. Moquist, T. Kodama, 2010, Angewandte Chemie.

Chiral Amino Alcohols via Catalytic Enantioselective Petasis Borono-Mannich Reactions

S. Schaus, Mathew J. Vetticatt, Victor Wambua, 2020 .

Factor quinolinone inhibitors disrupt spindles and multiple LSF (TFCP2)-protein interactions in mitosis, including with microtubule-associated proteins

A. Emili, S. Schaus, J. Shah, 2022, PloS one.

Brønsted base catalysts.

S. Schaus, A. Ting, Nolan T. Mcdougal, 2010, Topics in current chemistry.

Asymmetric Synthesis of Griffipavixanthone Employing a Chiral Phosphoric Acid-Catalyzed Cycloaddition.

S. Schaus, D. Coker, J. Porco, 2018, Journal of the American Chemical Society.

High-throughput Screening in Larval Zebrafish Identifies Novel Potent Sedative-hypnotics

S. Schaus, Wenqing Xu, Buwei Yu, 2018, Anesthesiology.

Enantioselective synthesis of 1,2-dihydronaphthalene-1-carbaldehydes by addition of boronates to isochromene acetals catalyzed by tartaric acid.

S. Schaus, Yi Luan, P. Moquist, 2015, Journal of the American Chemical Society.

Enantioselective addition of boronates to acyl imines catalyzed by chiral biphenols.

S. Schaus, Sha Lou, J. Bishop, 2009, Angewandte Chemie.

Identification of Small Molecules with Improved Potency against Orthopoxviruses from Vaccinia to Smallpox

Claire Marie Filone, S. Schaus, J. Connor, 2022, Antimicrobial agents and chemotherapy.

Catalytic diastereoselective petasis reactions.

S. Schreiber, S. Schaus, Giovanni Muncipinto, 2011, Angewandte Chemie.

Asymmetric Hetero-Diels−Alder Reactions Catalyzed by Chiral (Salen)Chromium(III) Complexes

S. Schaus, E. Jacobsen, J. Bran̊alt, 1998 .

Enantioselective Synthesis of Allenes by Catalytic Traceless Petasis Reactions.

R. J. Thomson, S. Schaus, Yao-Chen Jiang, 2017, Journal of the American Chemical Society.

The development of a novel HAuCl4@MOF catalyst and its catalytic application in the formation of dihydrochalcones.

S. Schaus, Jie Yu, Hongyi Gao, 2014, RSC advances.

Resveratrol attenuates L-DOPA-induced hydrogen peroxide toxicity in neuronal cells

S. Schaus, B. Yamamoto, A. Ho, 2012, Neuroreport.

Organocatalytic Asymmetric Mannich Reactions: New Methodology, Catalyst Design, and Synthetic Applications

S. Schaus, A. Ting, 2007 .

A cycloisomerization/Friedel-Crafts alkylation strategy for the synthesis of pyrano[3,4-b]indoles.

S. Schaus, J. Porco, M. R. Medeiros, 2011, Organic letters.

Asymmetric ring opening of meso epoxides with TMSCN catalyzed by (pybox)lanthanide complexes.

S. Schaus, E. Jacobsen, 2000, Organic letters.

Discovery of pyrazolopyrrolidinones as potent, broad-spectrum inhibitors of Leishmania infection

S. Schaus, Ignacio Cotillo, J. McKerrow, 2023, Frontiers in Tropical Diseases.

A general organic catalyst for asymmetric addition of stabilized nucleophiles to acyl imines

S. Schaus, A. Ting, C. Bode, 2006 .

Multicomponent Condensation Reactions via ortho-Quinone Methides.

S. Schaus, J. Panek, E. E. Allen, 2017, Organic letters.

Enantioselective Multicomponent Condensation Reactions of Phenols, Aldehydes, and Boronates Catalyzed by Chiral Biphenols.

S. Schaus, Y. Luan, J. Panek, 2015, Organic letters.

Enantioselective addition of boronates to o-quinone methides catalyzed by chiral biphenols.

S. Schaus, Y. Luan, 2012, Journal of the American Chemical Society.

Highly diastereoselective synthesis of bicyclo[3.2.1]octenones through phosphine-mediated condensations of 1,4-dien-3-ones.

S. Schaus, Nolan T. Mcdougal, 2006, Angewandte Chemie.

Asymmetric Petasis Borono-Mannich Allylation Reactions Catalyzed by Chiral Biphenols.

S. Schaus, Yao-Chen Jiang, 2017, Angewandte Chemie.

Asymmetric Mannich reactions of beta-keto esters with acyl imines catalyzed by cinchona alkaloids.

S. Schaus, Brandon M. Taoka, Sha Lou, 2005, Journal of the American Chemical Society.

Gold catalyzed cyclization of alkyne-tethered dihydropyrimidones.

S. Schaus, J. Porco, P. Dai, 2011, Organic letters.

Asymmetric allylboration of ketones catalyzed by chiral diols.

S. Schaus, Sha Lou, P. Moquist, 2006, Journal of the American Chemical Society.

Brønsted Acid/Lewis Acid Cooperatively Catalyzed Addition of Diazoester to 2H-chromene Acetals.

S. Schaus, Hongyi Gao, Y. Luan, 2014, European journal of organic chemistry.

The Development of the Asymmetric Morita—Baylis—Hillman Reaction Catalyzed by Chiral Brønsted Acids

S. Schaus, Nolan T. Mcdougal, Whitney L. Trevellini, 2004 .

Asymmetric Mannich Reactions of β-Keto Esters with Acyl Imines Catalyzed by Cinchona Alkaloids.

S. Schaus, Brandon M. Taoka, Sha Lou, 2005 .

An intramolecular inverse electron demand Diels–Alder approach to annulated α-carbolines

S. Schaus, Zhiyuan Ma, J. Snyder, 2012, Beilstein journal of organic chemistry.

Development of an enantioselective synthetic route to neocarzinostatin chromophore and its use for multiple radioisotopic incorporation.

S. Schaus, Yusheng Wu, A. Myers, 2002, Journal of the American Chemical Society.

Asymmetric petasis reactions catalyzed by chiral biphenols.

S. Schaus, Sha Lou, 2008, Journal of the American Chemical Society.

Morita–Baylis–Hillman, Vinylogous Morita–Baylis–Hillman, and Rauhut–Currier Reactions

S. Schaus, Nolan T. Mcdougal, Allison M. Wensley, 2016 .

Efficient construction of the clerodane decalin core by an asymmetric Morita-Baylis-Hillman reaction/Lewis acid promoted annulation strategy.

S. Schaus, S. A. Rodgen, 2006, Angewandte Chemie.

Diastereoselective Three-Component Synthesis of β-Amino Carbonyl Compounds Using Diazo Compounds, Boranes, and Acyl Imines under Catalyst-Free Conditions

S. Schaus, Y. Luan, Xiaowei Zhang, 2014, The Journal of organic chemistry.

Enantioselective synthesis of SNAP-7941: chiral dihydropyrimidone inhibitor of MCH1-R.

S. Schaus, J. M. Goss, 2008, The Journal of organic chemistry.

Asymmetric Mannich Reaction of Dicarbonyl Compounds with α‐Amido Sulfones Catalyzed by Cinchona Alkaloids and Synthesis of Chiral Dihydropyrimidones.

S. Schaus, P. Dai, Sha Lou, 2008 .

Asymmetric Mannich reaction of dicarbonyl compounds with alpha-amido sulfones catalyzed by cinchona alkaloids and synthesis of chiral dihydropyrimidones.

S. Schaus, P. Dai, Sha Lou, 2007, The Journal of organic chemistry.

Enantioselective Preparation of Dihydropyrimidones

S. Schaus, P. Dai, Sha Lou, 2009 .

Asymmetric Morita-Baylis-Hillman reactions catalyzed by chiral Brønsted acids.

S. Schaus, Nolan T. Mcdougal, 2003, Journal of the American Chemical Society.

Carbenoid insertions into the siliconhydrogen bond catalyzed by chiral copper (I) schiff base complexes

S. Schaus, L. Dakin, E. Jacobsen, 1998 .

Transcriptional response pathways in a yeast strain sensitive to saframycin a and a more potent analog: evidence for a common basis of activity.

S. Schaus, A. Plowright, A. Myers, 2002, Chemistry & biology.

Chemical library synthesis using convergent approaches.

Aaron B Beeler, Scott E Schaus, John A Porco, 2005, Current opinion in chemical biology.

Diene Synthesis by the Reductive Transposition of 1,2-Allenols

R. J. Thomson, S. Schaus, Abdallah B. Diagne, 2019, Synlett.

Enantioselective boronate additions to N-acyl quinoliniums catalyzed by tartaric acid.

S. Schaus, P. Moquist, T. Kodama, 2011, Organic letters.

Asymmetric propargylation of ketones using allenylboronates catalyzed by chiral biphenols.

David S. Barnett, S. Schaus, 2011, Organic letters.

Iron-catalyzed rearrangements and cycloaddition reactions of 2H-chromenes.

S. Schaus, Yi Luan, Huan Sun, 2011, Organic letters.

Metal-catalyzed cascade rearrangements of 3-alkynyl flavone ethers.

S. Schaus, J. Porco, Yuan Xiong, 2013, Organic letters.

Practical Access to Highly Enantioenriched C-3 Building Blocks via Hydrolytic Kinetic Resolution.

S. Schaus, E. Jacobsen, Michael E. Furrow, 1998, The Journal of organic chemistry.

Enantioselective synthesis of 3,4-chromanediones via asymmetric rearrangement of 3-allyloxyflavones.

S. Schaus, N. Berova, J. Porco, 2010, The Journal of organic chemistry.

Asymmetric Traceless Petasis Borono-Mannich Reactions of Enals: Reductive Transposition of Allylic Diazenes.

R. J. Thomson, S. Schaus, Yao-Chen Jiang, 2017, Angewandte Chemie.

Exploring skeletal diversity via ring contraction of glycal-derived scaffolds.

S. Schaus, J. Porco, G. Min, 2006, Organic letters.

[4 + 2]-Cycloaddition and 1,4-Addition of ortho-Quinone Methides by a Chiral Crotyl Silane.

S. Schaus, J. Panek, Christopher R Wong, 2019, Organic letters.

Skeletal diversity via cationic rearrangements of substituted dihydropyrans.

S. Schaus, J. Porco, M. R. Medeiros, 2010, Organic letters.

Practical Access to Highly Enantioenriched C-3 Building Blocks via Hydrolytic Kinetic Resolution.

S. Schaus, E. Jacobsen, Michael E. Furrow, 1998, The Journal of organic chemistry.

Dihydropyrimidine-Thiones and Clioquinol Synergize To Target β-Amyloid Cellular Pathologies through a Metal-Dependent Mechanism.

Daniel F Tardiff, S. Schaus, S. Lindquist, 2017, ACS chemical neuroscience.

Asymmetric Hetero-Diels—Alder Reactions Catalyzed by Chiral (Salen)Chromium(III) Complexes.

S. Schaus, E. Jacobsen, J. Braanalt, 1998 .

Multicomponent Mannich reactions with boron enolates derived from diazo esters and 9-BBN.

S. Schaus, Yi Luan, 2011, Organic letters.

Decarboxylative aldol reactions of allyl beta-keto esters via heterobimetallic catalysis.

S. Schaus, J. Westbrook, Sha Lou, 2004, Journal of the American Chemical Society.

Dynamic kinetic resolution of epichlorohydrin via enantioselective catalytic ring opening with TMSN3. Practical synthesis of aryl oxazolidinone antibacterial agents

S. Schaus, E. Jacobsen, 1996 .

Borrelidin induces the transcription of amino acid biosynthetic enzymes via a GCN4-dependent pathway.

Erin L Eastwood, S. Schaus, 2003, Bioorganic & medicinal chemistry letters.

Improvement of experimental testing and network training conditions with genome-wide microarrays for more accurate predictions of drug gene targets

Eric D. Kolaczyk, Lisa Pham, Lisa M. Christadore, 2014, BMC Systems Biology.

Transcription factor LSF-DNMT1 complex dissociation by FQI1 leads to aberrant DNA methylation and gene expression

S. Schaus, U. Hansen, S. Pradhan, 2016, Oncotarget.

Kinetic Resolution of Terminal Epoxides via Highly Regioselective and Enantioselective Ring Opening with TMSN3. An Efficient, Catalytic Route to 1,2‐Amino Alcohols.

S. Schaus, E. Jacobsen, J. Larrow, 1996 .

The transcription factor LSF: a novel oncogene for hepatocellular carcinoma.

Ulla Hansen, Dong Chen, Devanand Sarkar, 2012, American journal of cancer research.

Small molecule inhibitors of Late SV40 Factor (LSF) abrogate hepatocellular carcinoma (HCC): Evaluation using an endogenous HCC model

Lisa M. Christadore, S. Schaus, P. Fisher, 2015, Oncotarget.

Diversity-Oriented Synthesis Library Inhibitor of Orthopoxviruses from a Identification of a Pyridopyrimidinone

Claire Marie Filone, S. Schaus, K. Rubins, 2012 .

Identification of a Pyridopyrimidinone Inhibitor of Orthopoxviruses from a Diversity-Oriented Synthesis Library

Claire Marie Filone, S. Schaus, K. Rubins, 2011, Journal of Virology.

The microtubule-associated histone methyltransferase SET8, facilitated by transcription factor LSF, methylates α-tubulin

S. Schaus, U. Hansen, S. Pradhan, 2020, The Journal of Biological Chemistry.

Targeting the oncogene LSF with either the small molecule inhibitor FQI1 or siRNA causes mitotic delays with unaligned chromosomes, resulting in cell death or senescence

S. Schaus, J. Shah, C. Pedamallu, 2019, bioRxiv.

An in vitro comparison of shear bond strength of zirconia to enamel using different surface treatments.

S. Schaus, M. Finkelman, Roya Zandparsa, 2014, Journal of prosthodontics : official journal of the American College of Prosthodontists.

Two Naturally Occurring Mutations in the Type 1 Melanin-Concentrating Hormone Receptor Abolish Agonist-Induced Signaling

S. Schaus, J. Fortin, A. Kopin, 2010, Journal of Pharmacology and Experimental Therapeutics.

Factor quinolinone inhibitors alter cell morphology and motility by destabilizing interphase microtubules

S. Schaus, U. Hansen, Patrick Stoiber, 2021, Scientific Reports.

Perturbation Detection Through Modeling of Gene Expression on a Latent Biological Pathway Network: A Bayesian Hierarchical Approach

Eric D Kolaczyk, Lisa M Pham, Luis Carvalho, 2014, Journal of the American Statistical Association.

Convergent synthesis of a complex oxime library using chemical domain shuffling.

Aaron B. Beeler, Erin L Eastwood, S. Schaus, 2005, Organic letters.

Antiproliferative small-molecule inhibitors of transcription factor LSF reveal oncogene addiction to LSF in hepatocellular carcinoma

Lisa M. Christadore, S. Schaus, U. Hansen, 2012, Proceedings of the National Academy of Sciences.

Fluorescent Dendritic Micro-Hydrogels: Synthesis, Analysis and Use in Single-Cell Detection

Lisa M. Christadore, S. Schaus, M. Grinstaff, 2018, Molecules.

Transcription factor LSF facilitiates lysine methylation of α-tubulin by microtubule-associated SET8

S. Schaus, U. Hansen, S. Pradhan, 2019, bioRxiv.

LSF small molecule inhibitors phenocopy LSF-targeted siRNAs causing mitotic defects and senescence in cancer cells

S. Schaus, J. Shah, C. Pedamallu, 2019 .

Gene transcription analysis of Saccharomyces cerevisiae exposed to neocarzinostatin protein– chromophore complex reveals evidence of DNA damage, a potential mechanism of resistance, and consequences of prolonged exposure

S. Schaus, D. Cavalieri, A. Myers, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Practical Synthesis of Enantiopure Cyclic 1,2-Amino Alcohols via Catalytic Asymmetric Ring Opening of Meso Epoxides

S. Schaus, E. Jacobsen, J. Larrow, 1997 .