F. Holding

发表

An integrated approach utilizing artificial neural networks and SELDI mass spectrometry for the classification of human tumours and rapid identification of potential biomarkers

G. Li, Graham R. Ball, Ian O. Ellis, 2002, Bioinform..

Serine is a natural ligand and allosteric activator of pyruvate kinase M2

Eyal Gottlieb, Andris Jankevics, Karen H. Vousden, 2012, Nature.

In-gel activity-based protein profiling of a clickable covalent ERK1/2 inhibitor.

F. Holding, M. O’Reilly, T. Heightman, 2016, Molecular bioSystems.

Application of Native ESI-MS to Characterize Interactions between Compounds Derived from Fragment-Based Discovery Campaigns and Two Pharmaceutically Relevant Proteins

F. Holding, R. Zenobi, J. Coyle, 2018, SLAS discovery : advancing life sciences R & D.

Phase IIa safety and immunogenicity of a therapeutic vaccine, TA-GW, in persons with genital warts.

F. Holding, R. Fallon, J. S. Roberts, 1999, The Journal of infectious diseases.

Phase I safety and antigenicity of TA-GW: a recombinant HPV6 L2E7 vaccine for the treatment of genital warts.

F. Holding, R. Fallon, J. S. Roberts, 1999, Vaccine.

Native Mass Spectrometry Gives Insight into the Allosteric Binding Mechanism of M2 Pyruvate Kinase to Fructose-1,6-Bisphosphate.

F. Holding, R. Zenobi, D. Veprintsev, 2018, Biochemistry.

A prototype methodology combining surface‐enhanced laser desorption/ionization protein chip technology and artificial neural network algorithms to predict the chemoresponsiveness of breast cancer cell lines exposed to Paclitaxel and Doxorubicin under in vitro conditions

Graham Ball, Colin Creaser, Ian Ellis, 2003, Proteomics.

Enhanced immunogenicity of a recombinant genital warts vaccine adjuvanted with monophosphoryl lipid A.

F. Holding, M. Watts, G. Leesman, 1998, Vaccine.

Crystal structure of human CDK4 in complex with a D-type cyclin

Rajiv Chopra, Jeff Yon, Christoph Lengauer, 2009, Proceedings of the National Academy of Sciences.

Corrigendum: Serine is a natural ligand and allosteric activator of pyruvate kinase M2

F. Holding, A. Jankevics, E. Gottlieb, 2013, Nature.

Structure of the Epigenetic Oncogene MMSET and Inhibition by N-Alkyl Sinefungin Derivatives.

F. Holding, V. Berdini, M. Tortorici, 2016, ACS chemical biology.

Exploitation of a Novel Binding Pocket in Human Lipoprotein-Associated Phospholipase A2 (Lp-PLA2) Discovered through X-ray Fragment Screening.

C. Murray, F. Holding, V. Berdini, 2016, Journal of medicinal chemistry.

Fragment-Based Discovery of a Series of Allosteric-Binding Site Modulators of β-Glucocerebrosidase.

F. Holding, G. Chessari, R. Walser, 2024, Journal of medicinal chemistry.