H. Cai

发表

BACE1 is the major β-secretase for generation of Aβ peptides by neurons

H. Cai, Yanshu Wang, D. McCarthy, 2001, Nature Neuroscience.

Absence of DJ‐1 causes age‐related retinal abnormalities in association with increased oxidative stress

H. Cai, J. Hollyfield, B. Bell, 2017, Free radical biology & medicine.

Genetically engineered mouse models of neurodegenerative diseases

H. Cai, D. Borchelt, D. Price, 2002, Nature Neuroscience.

Low-level overexpression of wild type TDP-43 causes late-onset, progressive neurodegeneration and paralysis in mice

H. Cai, Jia Yu, Chunxing Yang, 2022, PloS one.

Low-level overexpression of wild type TDP-43 causes late-onset, progressive neurodegeneration and paralysis in mice

Robert H. Brown, H. Cai, Jia Yu, 2021, bioRxiv.

MicroRNA-205 regulates the expression of Parkinson's disease-related leucine-rich repeat kinase 2 protein.

Ping He, Veerle Baekelandt, Renée Vancraenenbroeck, 2013, Human molecular genetics.

Fine-Mapping, Gene Expression and Splicing Analysis of the Disease Associated LRRK2 Locus

D. Hernandez, M. Nalls, A. Singleton, 2013, PloS one.

Genetic ablation of dynactin p150Glued in postnatal neurons causes preferential degeneration of spinal motor neurons in aged mice

H. Cai, Lixin Sun, Jia Yu, 2018, Molecular Neurodegeneration.

BACE1 is the major beta-secretase for generation of Abeta peptides by neurons.

H. Cai, D. McCarthy, H. Wen, 2001, Nature neuroscience.

The G59S Mutation in p150glued Causes Dysfunction of Dynactin in Mice

H. Cai, Xian Lin, Chen Lai, 2007, The Journal of Neuroscience.

Regulation of endosomal motility and degradation by amyotrophic lateral sclerosis 2/alsin

H. Cai, B. Howell, Chengsong Xie, 2009, Molecular Brain.

Autophagy in neurodegenerative diseases: pathogenesis and therapy

H. Cai, W. Le, Fang Guo, 2018, Brain pathology.

Loss of leucine-rich repeat kinase 2 causes age-dependent bi-phasic alterations of the autophagy pathway

H. Cai, E. Giaime, J. Bonventre, 2012, Molecular Neurodegeneration.

Mutations in GBA2 cause autosomal-recessive cerebellar ataxia with spasticity.

Henry Houlden, Andrew B Singleton, D. Hernandez, 2013, American journal of human genetics.

Essential role for autophagy protein VMP1 in maintaining neuronal homeostasis and preventing axonal degeneration

H. Cai, Han-Ming Shen, W. Le, 2021, Cell death & disease.

Longitudinal Metabolomics Profiling of Parkinson’s Disease-Related α-Synuclein A53T Transgenic Mice

X. Chen, H. Cai, Lixin Sun, 2015, PloS one.

Fingerprint analysis of Huolingshengji Formula and its neuroprotective effects in SOD1G93A mouse model of amyotrophic lateral sclerosis

H. Cai, Y. Shao, Song Li, 2018, Scientific Reports.

Can BACE1 inhibition mitigate early axonal pathology in neurological diseases?

H. Cai, Chao Ma, W. Gai, 2013, Journal of Alzheimer's disease : JAD.

α-Synuclein Negatively Regulates Nurr1 Expression Through NF-κB-Related Mechanism

H. Cai, W. Le, Sheng Chen, 2020, Frontiers in Molecular Neuroscience.

α-Synuclein Mutation Inhibits Endocytosis at Mammalian Central Nerve Terminals

H. Cai, Lixin Sun, Jianhua Xu, 2016, The Journal of Neuroscience.

Experimental microembolism induces localized neuritic pathology in guinea pig cerebrum

H. Cai, P. Patrylo, Xue-gang Luo, 2015, Oncotarget.

BACE1 elevation is associated with aberrant limbic axonal sprouting in epileptic CD1 mice

H. Cai, G. Rose, P. Patrylo, 2012, Experimental Neurology.

Distinct Connectivity and Functionality of Aldehyde Dehydrogenase 1a1-Positive Nigrostriatal Dopaminergic Neurons in Motor Learning.

H. Cai, Lixin Sun, Jia Yu, 2019, Cell reports.

NEDD4-mediated HSF1 degradation underlies α-synucleinopathy

H. Cai, E. Masliah, P. Nelson, 2015, Human molecular genetics.

Striosomes constrain locomotor vigor with respect to an innate valence differential

H. Cai, Bo Liang, Da-Ting Lin, 2022, bioRxiv.

The essential role of transcription factor Pitx3 in preventing mesodiencephalic dopaminergic neurodegeneration and maintaining neuronal subtype identities during aging

H. Cai, Song Li, W. Le, 2021, Cell Death & Disease.

Oxidative stress regulation by DJ-1 in the retinal pigment epithelium.

H. Cai, Xiaoping Yang, V. Bonilha, 2014, Advances in experimental medicine and biology.

Low-level overexpression of wild type TDP-43 causes late-onset, progressive neurodegeneration and paralysis in mice

Robert H. Brown, H. Cai, Jia Yu, 2021, bioRxiv.

Deficiency in endocannabinoid synthase DAGLB contributes to early onset Parkinsonism and murine nigral dopaminergic neuron dysfunction

A. Singleton, Mary B Makarious, C. Blauwendraat, 2022, Nature Communications.

Parkinson’s disease-related Leucine-rich repeat kinase 2 modulates nuclear morphology and genomic stability in striatal projection neurons during aging

H. Cai, Lixin Sun, Shengdi Chen, 2020, Molecular Neurodegeneration.

LRRK2 modulates microglial activity through regulation of chemokine (C-X3-C) receptor 1 -mediated signalling pathways.

H. Cai, Lixin Sun, V. Koliatsos, 2016, Human molecular genetics.

Title : Leucine-rich Repeat Kinase 2 regulates Sec 16 A at ER exit sites to allow ER-Golgi export

H. Cai, Lixin Sun, Jia Yu, 2014 .

Parkin and PINK1 mitigate STING-induced inflammation

H. Cai, J. Burman, Jennifer Martinez, 2018, Nature.

Anti-oxidant polydatin (piceid) protects against substantia nigral motor degeneration in multiple rodent models of Parkinson’s disease

H. Cai, S. Gong, F. Liao, 2015, Molecular Neurodegeneration.

Quercetin targets the interaction of calcineurin with LxVP-type motifs in immunosuppression.

H. Cai, Q. Wei, Jing Li, 2016, Biochimie.

Amyloid plaque pathogenesis in 5XFAD mouse spinal cord: retrograde transneuronal modulation after peripheral nerve injury

H. Cai, P. Patrylo, Xue-gang Luo, 2012, Neurotoxicity Research.

Mice deficient in the ALS2 gene exhibit lymphopenia and abnormal hematopietic function

H. Cai, Jichun Chen, K. Keyvanfar, 2007, Journal of Neuroimmunology.

Amyotrophic lateral sclerosis-related VAPB P56S mutation differentially affects the function and survival of corticospinal and spinal motor neurons.

Michael J. O'Donovan, N. Chub, H. Cai, 2013, Human molecular genetics.

Deficiency in the ALS2 gene does not affect the motor neuron degeneration in SOD1G93A transgenic mice

H. Cai, Xian Lin, Hoon Shim, 2007, Neurobiology of Aging.

Toll-Like Receptors Promote Mitochondrial Translocation of Nuclear Transcription Factor Nuclear Factor of Activated T-Cells in Prolonged Microglial Activation

H. Cai, Lixin Sun, Jia Yu, 2015, The Journal of Neuroscience.

Nicastrin is required for assembly of presenilin/gamma-secretase complexes to mediate Notch signaling and for processing and trafficking of beta-amyloid precursor protein in mammals.

H. Cai, D. Price, P. Wong, 2003, The Journal of neuroscience : the official journal of the Society for Neuroscience.

Leucine‐rich repeat kinase 2 regulates Sec16A at ER exit sites to allow ER–Golgi export

X. Chen, H. Cai, Lixin Sun, 2014, The EMBO journal.

Amyloid β peptide load is correlated with increased β-secretase activity in sporadic Alzheimer's disease patients

H. Cai, D. Price, P. Wong, 2004 .

Evidence that γ-secretase mediates oxidative stress-induced β-secretase expression in Alzheimer's disease

M. Mattson, Sung-Chun Tang, H. Cai, 2010, Neurobiology of Aging.

BACE1, a Major Determinant of Selective Vulnerability of the Brain to Amyloid-β Amyloidogenesis, is Essential for Cognitive, Emotional, and Synaptic Functions

H. Cai, H. Wen, D. Borchelt, 2005, The Journal of Neuroscience.

BACE1 Elevation is Involved in Amyloid Plaque Development in the Triple Transgenic Model of Alzheimer’s Disease: Differential Aβ Antibody Labeling of Early-Onset Axon Terminal Pathology

H. Cai, F. LaFerla, R. Struble, 2011, Neurotoxicity Research.

Parkin and PINK1 mitigate STING-induced inflammation

X. Chen, H. Cai, J. Burman, 2018, Nature.

Animal Models of Parkinson's Disease

David S. Park, H. Cai, Y. Imai, 2011, Parkinson's disease.

Nicastrin Is Required for Assembly of Presenilin/γ-Secretase Complexes to Mediate Notch Signaling and for Processing and Trafficking of β-Amyloid Precursor Protein in Mammals

H. Cai, D. Price, P. Wong, 2003, The Journal of Neuroscience.

Genetically engineered models relevant to neurodegenerative disorders

H. Cai, D. Borchelt, D. Price, 2001, Journal of Molecular Neuroscience.

Astrocytic expression of Parkinson's disease-related A53T α-synuclein causes neurodegeneration in mice

H. Cai, Lixin Sun, Chengsong Xie, 2010, Molecular Brain.

Leucine-Rich Repeat Kinase 2 Regulates the Progression of Neuropathology Induced by Parkinson's-Disease-Related Mutant α-synuclein

H. Cai, Lixin Sun, J. Troncoso, 2009, Neuron.

Cloning and Characterization of Neuropilin-1-Interacting Protein: A PSD-95/Dlg/ZO-1 Domain-Containing Protein That Interacts with the Cytoplasmic Domain of Neuropilin-1

H. Cai, R. Reed, 1999, The Journal of Neuroscience.

AGE-induced neuronal cell death is enhanced in G2019S LRRK2 mutation with increased RAGE expression

H. Cai, Chengsong Xie, H. J. Cho, 2018, Translational Neurodegeneration.

Aldehyde Dehydrogenase 1 making molecular inroads into the differential vulnerability of nigrostriatal dopaminergic neuron subtypes in Parkinson’s disease

H. Cai, Lixin Sun, Jinhui Ding, 2014, Translational Neurodegeneration.

Aldehyde dehydrogenase 1 defines and protects a nigrostriatal dopaminergic neuron subpopulation.

H. Cai, Lixin Sun, Jia Yu, 2014, The Journal of clinical investigation.

Partial loss of TDP-43 function causes phenotypes of amyotrophic lateral sclerosis

Robert H. Brown, H. Cai, M. Moore, 2014, Proceedings of the National Academy of Sciences.

α-synuclein, LRRK2 and their interplay in Parkinson's disease.

H. Cai, Guoxiang Liu, L. Aliaga, 2012, Future neurology.

LRRK2 regulates synaptogenesis and dopamine receptor activation through modulation of PKA activity

Nicole A. Crowley, D. Lovinger, H. Cai, 2014, Nature Neuroscience.

A Direct Interaction between Leucine-rich Repeat Kinase 2 and Specific β-Tubulin Isoforms Regulates Tubulin Acetylation*

H. Cai, M. Cookson, V. Baekelandt, 2013, The Journal of Biological Chemistry.

The kinase LRRK2 is a regulator of the transcription factor NFAT that modulates the severity of inflammatory bowel disease

Wei Lu, H. Cai, M. Lenardo, 2011, Nature Immunology.

Phosphorylation of Ezrin/Radixin/Moesin Proteins by LRRK2 Promotes the Rearrangement of Actin Cytoskeleton in Neuronal Morphogenesis

H. Cai, Lixin Sun, V. Baekelandt, 2009, The Journal of Neuroscience.

RNA binding activity of the recessive parkinsonism protein DJ-1 supports involvement in multiple cellular pathways

Ming Zhan, Nancy M Bonini, Myriam Gorospe, 2008, Proceedings of the National Academy of Sciences.

Diverse midbrain dopaminergic neuron subtypes and implications for complex clinical symptoms of Parkinson’s disease

H. Cai, Lixin Sun, K. Carmichael, 2021, Ageing and neurodegenerative diseases.

Function and Regulation of ALDH1A1-Positive Nigrostriatal Dopaminergic Neurons in Motor Control and Parkinson’s Disease

H. Cai, Lixin Sun, Zayd M. Khaliq, 2021, Frontiers in Neural Circuits.

Connectivity and Functionality of the Globus Pallidus Externa Under Normal Conditions and Parkinson's Disease

H. Cai, Jun-bing Wu, W. Le, 2021, Frontiers in Neural Circuits.

Leucine-Rich Repeat Kinase 2 (Lrrk2) Deficiency Diminishes the Development of Experimental Autoimmune Uveitis (EAU) and the Adaptive Immune Response

Samuel J. Hinshaw, X. Chen, H. Cai, 2015, PloS one.

The Chaperone Activity of Heat Shock Protein 90 Is Critical for Maintaining the Stability of Leucine-Rich Repeat Kinase 2

H. Cai, Lixin Sun, G. Chiosis, 2008, The Journal of Neuroscience.

Activation of autophagy attenuates motor deficits and extends lifespan in a C. elegans model of ALS.

H. Cai, W. Le, Hui Xu, 2022, Free radical biology & medicine.

γ‐Secretase binding sites in aged and Alzheimer's disease human cerebrum: the choroid plexus as a putative origin of CSF Aβ

H. Cai, R. Struble, G. Rose, 2013, The European journal of neuroscience.

The IkappaB Kinase Family Phosphorylates the Parkinson’s Disease Kinase LRRK2 at Ser935 and Ser910 during Toll-Like Receptor Signaling

Patrick G. A. Pedrioli, P. Cohen, H. Cai, 2012, PloS one.

Regulation of Synaptic Amyloid-β Generation through BACE1 Retrograde Transport in a Mouse Model of Alzheimer's Disease

David J. Margolis, H. Cai, A. Kusnecov, 2017, The Journal of Neuroscience.

Mitochondrial respiratory inhibition and oxidative stress elevate β-secretase (BACE1) proteins and activity in vivo in the rat retina

H. Cai, R. Struble, K. Xiong, 2007, Experimental Brain Research.

Amyotrophic Lateral Sclerosis 2-Deficiency Leads to Neuronal Degeneration in Amyotrophic Lateral Sclerosis through Altered AMPA Receptor Trafficking

J. Zhu, R. Huganir, H. Cai, 2006, The Journal of Neuroscience.

Conditional Expression of Parkinson's Disease-Related Mutant α-Synuclein in the Midbrain Dopaminergic Neurons Causes Progressive Neurodegeneration and Degradation of Transcription Factor Nuclear Receptor Related 1

D. Lovinger, H. Cai, Jia Yu, 2012, The Journal of Neuroscience.

Opioid system in L-DOPA-induced dyskinesia

H. Cai, Jing Pan, 2017, Translational Neurodegeneration.

Activation of protein kinase C modulates BACE1-mediated β-secretase activity

H. Cai, Chengsong Xie, Hoon Shim, 2008, Neurobiology of Aging.

Activation of protein kinase C modulates BACE1-mediated beta-secretase activity.

H. Cai, Chengsong Xie, Hoon Shim, 2008, Neurobiology of aging.

Lipolysaccharide-Induced Neuroinflammation Is Associated with Alzheimer-Like Amyloidogenic Axonal Pathology and Dendritic Degeneration in Rats.

H. Cai, P. Patrylo, X. Deng, 2014, Advances in Alzheimer's disease.

Essential role for autophagy protein VMP1 in maintaining neuronal homeostasis and preventing axonal degeneration

H. Cai, W. Le, Xinyao Liu, 2021, Cell Death & Disease.

Amyloid beta peptide load is correlated with increased beta-secretase activity in sporadic Alzheimer's disease patients.

H. Cai, P. Wong, Rena Li, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Lack of human-like extracellular sortilin neuropathology in transgenic Alzheimer’s disease model mice and macaques

H. Cai, Y. Chu, P. Patrylo, 2018, Alzheimer's Research & Therapy.

Sortilin Fragments Deposit at Senile Plaques in Human Cerebrum

H. Cai, Y. Chu, B. Tang, 2017, Front. Neuroanat..

Chronic Temporal Lobe Epilepsy Is Associated with Enhanced Alzheimer-Like Neuropathology in 3×Tg-AD Mice

H. Cai, F. LaFerla, S. Oddo, 2012, PloS one.

BACE1 Elevation is Involved in Amyloid Plaque Development in the Triple Transgenic Model of Alzheimer’s Disease: Differential Aβ Antibody Labeling of Early-Onset Axon Terminal Pathology

H. Cai, F. LaFerla, R. Struble, 2012, Neurotoxicity Research.

In Vivo Olfactory Model of APP-Induced Neurodegeneration Reveals a Reversible Cell-Autonomous Function

Leonardo Belluscio, Ning Cheng, H. Cai, 2011, The Journal of Neuroscience.

β‐Secretase‐1 elevation in aged monkey and Alzheimer’s disease human cerebral cortex occurs around the vasculature in partnership with multisystem axon terminal pathogenesis and β‐amyloid accumulation

H. Cai, J. Kordower, Y. Chu, 2010, The European journal of neuroscience.

Functional deprivation promotes amyloid plaque pathogenesis in Tg2576 mouse olfactory bulb and piriform cortex

H. Cai, R. Struble, K. Xiong, 2010, The European journal of neuroscience.

β‐Secretase‐1 elevation in transgenic mouse models of Alzheimer’s disease is associated with synaptic/axonal pathology and amyloidogenesis: implications for neuritic plaque development

H. Cai, R. Struble, K. Xiong, 2009, The European journal of neuroscience.

Lack of human-like extracellular sortilin neuropathology in transgenic Alzheimer’s disease model mice and macaques

H. Cai, Y. Chu, P. Patrylo, 2018, Alzheimer's Research & Therapy.

A calcineurin- and NFAT-dependent pathway is involved in α-synuclein-induced degeneration of midbrain dopaminergic neurons.

H. Cai, Lixin Sun, Jia Yu, 2014, Human molecular genetics.

Peptides derived from transcription factor EB bind to calcineurin at a similar region as the NFAT-type motif.

H. Cai, Huan Yang, Q. Wei, 2017, Biochimie.

Acute Hypoxia Induced an Imbalanced M1/M2 Activation of Microglia through NF-κB Signaling in Alzheimer’s Disease Mice and Wild-Type Littermates

H. Cai, Song Li, W. Le, 2017, Front. Aging Neurosci..

Loss of DJ-1 elicits retinal abnormalities, visual dysfunction, and increased oxidative stress in mice.

H. Cai, Xiaoping Yang, J. Hollyfield, 2015, Experimental eye research.

Synaptic vesicle glycoprotein 2C (SV2C) modulates dopamine release and is disrupted in Parkinson disease

Alison I. Bernstein, H. Cai, G. Miller, 2017, Proceedings of the National Academy of Sciences.

DJ-1 is Essential for Long-Term Depression at Hippocampal CA1 Synapses

M. Mattson, H. Cai, Yue Wang, 2008, NeuroMolecular Medicine.

Genetic ablation of dynactin p150Glued in postnatal neurons causes preferential degeneration of spinal motor neurons in aged mice

H. Cai, Lixin Sun, Jia Yu, 2018, Molecular Neurodegeneration.

Nurr1Cd11bcre conditional knockout mice display inflammatory injury to nigrostriatal dopaminergic neurons.

H. Cai, W. Le, Xinyao Liu, 2020, Glia.

No apparent transmission of transgenic α–synuclein into nigrostriatal dopaminergic neurons in multiple mouse models

X. Chen, H. Cai, Lixin Sun, 2015, Translational Neurodegeneration.

Selective expression of Parkinson's disease-related Leucine-rich repeat kinase 2 G2019S missense mutation in midbrain dopaminergic neurons impairs dopamine release and dopaminergic gene expression.

D. Lovinger, H. Cai, Lixin Sun, 2015, Human molecular genetics.

Deficiency of Perry syndrome-associated p150Glued in midbrain dopaminergic neurons leads to progressive neurodegeneration and endoplasmic reticulum abnormalities

H. Cai, Jia Yu, C. Sgobio, 2023, npj Parkinson's Disease.

ALDH1A1 regulates postsynaptic μ–opioid receptor expression in dorsal striatal projection neurons and mitigates dyskinesia through transsynaptic retinoic acid signaling

H. Cai, Lixin Sun, Jia Yu, 2019, Scientific Reports.

Unbalanced calcium channel activity underlies selective vulnerability of nigrostriatal dopaminergic terminals in Parkinsonian mice

D. Lovinger, H. Cai, Lixin Sun, 2019, Scientific Reports.

Optogenetic Measurement of Presynaptic Calcium Transients Using Conditional Genetically Encoded Calcium Indicator Expression in Dopaminergic Neurons

D. Lovinger, H. Cai, Lixin Sun, 2014, PloS one.

Alsin and the Molecular Pathways of Amyotrophic Lateral Sclerosis

H. Cai, Jinhui Ding, J. Chandran, 2007, Molecular Neurobiology.

Loss of ALS2 Function Is Insufficient to Trigger Motor Neuron Degeneration in Knock-Out Mice But Predisposes Neurons to Oxidative Stress

Ahmet Hoke, H. Cai, H. Wen, 2005, The Journal of Neuroscience.

The Crucial Roles of Pitx3 in Midbrain Dopaminergic Neuron Development and Parkinson’s Disease-Associated Neurodegeneration

H. Cai, Guangdong Liu, Xi Chen, 2023, International journal of molecular sciences.

Delineating the role of glutathione peroxidase 4 in protecting cells against lipid hydroperoxide damage and in Alzheimer's disease.

H. Cai, V. Gladyshev, B. Carlson, 2010, Antioxidants & redox signaling.

ALS2/Alsin Knockout Mice and Motor Neuron Diseases

H. Cai, Chengsong Xie, Xian Lin, 2008, Neurodegenerative Diseases.

Progressive behavioral deficits in DJ-1-deficient mice are associated with normal nigrostriatal function

H. Cai, P. Wong, J. Crawley, 2008, Neurobiology of Disease.

AGE-induced neuronal cell death is enhanced in G2019S LRRK2 mutation with increased RAGE expression

H. Cai, Chengsong Xie, H. J. Cho, 2018, Translational Neurodegeneration.

Correction to: Parkinson’s disease-related Leucine-rich repeat kinase 2 modulates nuclear morphology and genomic stability in striatal projection neurons during aging

H. Cai, Lixin Sun, Shengdi Chen, 2020, Molecular Neurodegeneration.

LRRK2 function on actin and microtubule dynamics in Parkinson’s disease

H. Cai, L. Parisiadou, 2010, Communicative & integrative biology.

Amyloid plaque pathogenesis in 5XFAD mouse spinal cord: retrograde transneuronal modulation after peripheral nerve injury

H. Cai, P. Patrylo, Xue-gang Luo, 2013, Neurotoxicity Research.

Pathological characteristics of axons and proteome patterns in midbrain dopaminergic neurodegeneration induced by WDR45-deficiency

H. Cai, Han Yang, Song Li, 2023, Research square.

Non-neuronal and neuronal BACE1 elevation in association with angiopathic and leptomeningeal β-amyloid deposition in the human brain

H. Cai, Chao Ma, W. Gai, 2015, BMC Neurology.

Tau haploinsufficiency causes prenatal loss of dopaminergic neurons in the ventral tegmental area and reduction of transcription factor orthodenticle homeobox 2 expression

H. Cai, Xian Lin, Bin Jiang, 2017, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Synaptic vesicle glycoprotein 2C (SV2C) modulates dopamine release and is disrupted in Parkinson’s disease

Alison I. Bernstein, H. Cai, G. Miller, 2016, bioRxiv.

Aldehyde dehydrogenase 1–positive nigrostriatal dopaminergic fibers exhibit distinct projection pattern and dopamine release dynamics at mouse dorsal striatum

D. Lovinger, H. Cai, Margaret I Davis, 2017, Scientific Reports.

Opioid system in L-DOPA-induced dyskinesia

H. Cai, Jing Pan, 2017, Translational Neurodegeneration.

Tau knockout exacerbates degeneration of parvalbumin‐positive neurons in substantia nigra pars reticulata in Parkinson's disease‐related α‐synuclein A53T mice

H. Cai, Z. Li, Jinhui Ding, 2020, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Tau Deficiency Down-Regulated Transcription Factor Orthodenticle Homeobox 2 Expression in the Dopaminergic Neurons in Ventral Tegmental Area and Caused No Obvious Motor Deficits in Mice

H. Cai, P. Xu, Xian Lin, 2018, Neuroscience.

Deficiency in endocannabinoid synthase DAGLB contributes to Parkinson’s disease and dopaminergic neuron dysfunction

D. Lovinger, H. Cai, P. Chan, 2021, bioRxiv.

LRRK2 regulates synaptogenesis and dopamine receptor activation through modulation of PKA activity

Nicole A. Crowley, D. Lovinger, H. Cai, 2014, Nature Neuroscience.

ALDH1A1 regulates postsynaptic μ–opioid receptor expression in dorsal striatal projection neurons and mitigates dyskinesia through transsynaptic retinoic acid signaling

H. Cai, Lixin Sun, Jia Yu, 2019, Scientific Reports.

Synaptic vesicle glycoprotein 2C (SV2C) modulates dopamine release and is disrupted in Parkinson’s disease

Alison I. Bernstein, H. Cai, G. Miller, 2016, bioRxiv.

Unbalanced calcium channel activity underlies selective vulnerability of nigrostriatal dopaminergic terminals in Parkinsonian mice

D. Lovinger, H. Cai, Lixin Sun, 2019, Scientific Reports.

The Brain's Susceptibility to Amyloid Plaques

H. Cai, P. Wong, D. Price, 2001, Science.

Evidence that gamma-secretase mediates oxidative stress-induced beta-secretase expression in Alzheimer's disease.

M. Mattson, Sung-Chun Tang, H. Cai, 2010, Neurobiology of aging.

A Direct Interaction between Leucine-rich Repeat Kinase 2 and Specific-Tubulin Isoforms Regulates Tubulin Acetylation Journal Item

H. Cai, M. Cookson, V. Baekelandt, 2018 .

Aldehyde dehydrogenase 1 defines and protects a nigrostriatal dopaminergic neuron subpopulation.

H. Cai, Lixin Sun, Jia Yu, 2014, The Journal of clinical investigation.